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https://www.readbyqxmd.com/read/28817898/re-short-form-charlson-comorbidity-index-for-assessment-of-perioperative-mortality-after-radical-cystectomy
#1
David F Penson
No abstract text is available yet for this article.
September 2017: Journal of Urology
https://www.readbyqxmd.com/read/28817654/investigating-spousal-concordance-of-diabetes-through-statistical-analysis-and-data-mining
#2
Jong-Yi Wang, Chiu-Shong Liu, Chi-Hsuan Lung, Ya-Tun Yang, Ming-Hung Lin
OBJECTIVE: Spousal clustering of diabetes merits attention. Whether old-age vulnerability or a shared family environment determines the concordance of diabetes is also uncertain. This study investigated the spousal concordance of diabetes and compared the risk of diabetes concordance between couples and noncouples by using nationally representative data. METHODS: A total of 22,572 individuals identified from the 2002-2013 National Health Insurance Research Database of Taiwan constituted 5,643 couples and 5,643 noncouples through 1:1 dual propensity score matching (PSM)...
2017: PloS One
https://www.readbyqxmd.com/read/28817502/stroke-related-disease-comorbidity-and-secondary-stroke-prevention-practices-among-young-stroke-survivors
#3
Gayenell S Magwood, Brandi M White, Charles Ellis
BACKGROUND: Although ischemic stroke incidence has been in decline over the past 60 years, the same has not been observed among individuals younger than 55 years. Recent reports have shown a substantial increase in young stroke incidence, yet little is known about young stroke survivors. OBJECTIVE: The aim of this study was to examine the disease comorbidity profile and secondary prevention practices in stroke survivors younger than 50 years. METHODS: This study used a retrospective data analysis of secondary stroke prevention practices among young stroke survivors using data from the 2015 National Health Interview Survey...
August 16, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28817407/nonoperative-management-of-labral-tears-of-the-hip-in-adolescent-athletes-description-of-sports-participation-interventions-comorbidity-and-outcomes
#4
Andrea Cianci, Dai Sugimoto, Andrea Stracciolini, Yi-Meng Yen, Mininder S Kocher, Pierre A dʼHemecourt
CONTEXT: Hip injury among young athletes is increasing, especially hip labral tears. Some tears may require surgical intervention, especially if they are associated with boney pathology such as femoroacetabular impingement (FAI). A protocol for nonoperative treatment of the hip labral tears is not well established. OBJECTIVE: To identify current nonoperative treatment options, comorbidities, sports participation, and outcomes of adolescent athletes who were diagnosed with hip labral tears...
August 16, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28817367/nutrition-implications-for-long-term-survivors-of-pancreatic-cancer-surgery
#5
Maria Q B Petzel, Leah Hoffman
With slowly increasing survival rates in pancreatic cancer and international consensus guidelines recommending surgical resection of premalignant lesions, survival post-pancreatic resection is increasing. With longer survival time, the significant comorbidities of such major surgery have far-reaching effects on the nutrition status of the survivor of pancreatic cancer. This review describes the many nutrition-related side effects of pancreatic surgery, including the development of pancreatic enzyme insufficiency, micronutrient deficiencies, diabetes, fatty liver, and metabolic bone disease...
August 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28817303/chrna7-deletions-are-enriched-in-risperidone-treated-children-and-adolescents
#6
Madelyn A Gillentine, Janson J White, Christopher M Grochowski, James R Lupski, Christian P Schaaf, Chadi A Calarge
OBJECTIVE: Aggression is among the most common indications for referral to child and adolescent mental health services and is often challenging to treat. Understanding the biological underpinnings of aggression could help optimize treatment efficacy. Neuronal nicotinic acetylcholine receptors (nAChRs), specifically the α7 nAChR, encoded by the gene CHRNA7, have been implicated in aggressive behaviors in animal models as well as humans. Copy number variants (CNVs) of CHRNA7 are found in individuals with neuropsychiatric disorders, often with comorbid aggression...
August 17, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28817237/dysregulation-of-wound-healing-mechanisms-in-diabetes-and-the-importance-of-negative-pressure-wound-therapy-npwt
#7
Mogher Khamaisi, Sarit Balanson
Diabetes is a serious disease with severe side effects and comorbidities. Diabetic foot with its chronic non-healing ulcers, or diabetic food ulcers (DFU) as they are commonly called, can be devastating, even leading to amputation. Many therapies exist to assist and improve wound healing. One exciting discovery is the use of negative pressure wound therapy (NPWT) as an adjunct to standard treatment. Few studies have substantively explored the molecular mechanisms of NPWT and why we see improved wound healing, a concept that demands more research...
August 17, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28816989/disease-duration-of-rheumatoid-arthritis-is-a-predictor-of-vascular-stiffness-a-cross-sectional-study-in-patients-without-known-cardiovascular-comorbidities-a-strobe-compliant-article
#8
Mónica Vázquez-Del Mercado, Eduardo Gomez-Bañuelos, Efrain Chavarria-Avila, Ernesto Cardona-Muñoz, Carlos Ramos-Becerra, Adrián Alanis-Sanchez, David Cardona-Muller, Fernando Grover-Paez, Felipe de J Perez-Vazquez, Rosa-Elena Navarro-Hernandez, Jorge M Valadez-Soto, Adan A Saldaña-Millan, Lorena Gonzalez-Rosas, Gabriel Ramos-Lopez, Marcelo H Petri, Magnus Bäck
The aim of this study was to analyze the impact of disease duration on carotid to femoral pulse wave velocity (cfPWV) in rheumatoid arthritis (RA) patients without either known traditional cardiovascular risk factors or previous comorbidities.Patients with RA diagnosis attending the rheumatology outpatient clinic of Hospital Civil Juan I. Menchaca, Guadalajara, Mexico, were analyzed. A total of 106 RA patients without known traditional cardiovascular risk factors were selected. All subjects were evaluated for RA disease duration, RA disease activity score on 28 joints (DAS28), serum lipids, rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816983/characteristics-of-turkish-patients-with-elderly-onset-psoriatic-arthritis-a-retrospective-cohort-study
#9
Senol Kobak, Fidan Yildiz, Ahmet Karaarslan, Huseyin Semiz, Mehmet Orman
Psoriatic arthritis (PsA) is a chronic inflamatory disease characterized with axial and peripheral joints involvement. It rarely affects patients older than 65 years old.The purpose of this study is to compare and evaluate the demographic, clinical and laboratory features of elderly-onset psoriatic arthritis (EOPsA) and young-onset (YOPsA) patients.A total of 180 patients diagnosed with PsA according to CASPAR criteria and followed-up in single center were included in this study. The patients with initial symptoms started after age 65 were accepted as EOPsA...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816975/incidence-and-risk-factors-of-posterior-cage-migration-following-decompression-and-instrumented-fusion-for-degenerative-lumbar-disorders
#10
Hua Li, Hui Wang, Yanbo Zhu, Wenyuan Ding, Qian Wang
The aim of this study was to explore the incidence and risk factors for posterior cage migration (PCM) following decompression and instrumented fusion for degenerative lumbar disorders, and hope to provide references in decision making and surgical planning for spine surgeons.By retrieving the medical records from January 2011 to December 2015, 286 patients were retrospectively reviewed. According to the occurrence of PCM, patients were divided into 2 groups: PCM group and non-PCM (N-PCM). To investigate risk values for PCM, 3 categorized factors were analyzed statistically: patient characteristics: age, sex, body mass index, bone mineral density, duration of disease, diagnosis, comorbidity, smoke; surgical variables: surgery time, blood loss, surgical strategy, cage morphology, cage size, surgical segment, fusion number, source of bone graft, surgeon experience; radiographic parameters: preoperative lumbar lordosis, correction of lumbar lordosis, preoperative lumbar mobility, preoperative intervertebral height, change of intervertebral height, Modic changes, paraspinal muscle degeneration...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816917/factors-associated-with-developmental-behavioral-pediatricians-prescribing-psychotropic-medication-to-children-with-autism-spectrum-disorder-a-study-of-three-dbpnet-sites
#11
Carissa Jackel, Justine Shults, Susan Wiley, Jareen Meinzen-Derr, Marilyn Augustyn, Nathan Blum
OBJECTIVE: Psychotropic medications are frequently prescribed to children with autism spectrum disorder (ASD), but little is known about the prescribing practices of developmental-behavioral pediatricians (DBPs). Our objective was to determine whether clinical site, age, insurance, or comorbidities influenced DBPs prescribing psychotropic medication for children with ASD. METHODS: A retrospective analysis was performed using electronic health record data of all patients with ASD seen at 3 academic developmental-behavioral pediatrics (DBP) clinical programs from January 2010 to December 2011...
August 10, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816896/factors-associated-with-adverse-events-in-inpatient-elective-spine-knee-and-hip-orthopaedic-surgery
#12
Dov B Millstone, Anthony V Perruccio, Elizabeth M Badley, Y Raja Rampersaud
BACKGROUND: Orthopaedic procedures for degenerative musculoskeletal conditions (predominantly osteoarthritis and spinal stenosis) represent an increasing burden on the health-care system. These procedures are also associated with adverse event rates and related cost. The objective of this study was to identify risk factors for adverse events associated with orthopaedic surgeries as captured within a common clinical point-of-care system for documenting adverse events (Orthopaedic Surgical AdVerse Events Severity [OrthoSAVES] system)...
August 16, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28816877/fractures-in-spinal-ankylosing-disorders-a-narrative-review-of-disease-and-injury-types-treatment-techniques-and-outcomes
#13
Tarush Rustagi, Doniel Drazin, Cumhur Oner, Jonathan York, Gregory D Schroeder, Alexander R Vaccaro, Rod J Oskouian, Jens R Chapman
INTRODUCTION: Spinal ankylosing disorders encompass ankylosing spondylitis (AS), disseminated hyperostosis of the spine, and end-stage spondylosis. All these result in a stiffened and frequently deformed spinal column. This makes the spinal column highly susceptible to severe injuries that are commonly associated with unfavorable outcomes. Improved understanding of the underlying disease processes and clinical comorbidities may alter the poor injury related morbidity and mortality outcomes...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816875/controversies-in-the-management-of-geriatric-odontoid-fractures
#14
Scott C Wagner, Gregory D Schroeder, Christopher K Kepler, Alexander J Schupper, Frank Kandziora, Emiliano N Vialle, Cumhur Oner, Michael G Fehlings, Alexander R Vaccaro
Fractures of the odontoid process of C2 have become increasingly prevalent in the aging population and are typically associated with a high incidence of morbidity. Dens fractures comprise the majority of all cervical fractures in patients older than 80 years and remain the most common cervical fracture pattern in all geriatric patients. Type II odontoid fractures have been associated with limited healing potential, and both nonoperative and operative management are associated with high mortality rates. Historically, there has been some debate in the literature with regards to optimal management strategies to maximize outcomes in geriatric patients...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816835/acute-worsening-of-tics-on-varenicline
#15
Shivam Om Mittal, Bryan T Klassen, Anhar Hassan, James H Bower, Elizabeth A Coon
OBJECTIVE: The aim of this study was to report worsening of Tourette syndrome (TS) in 2 patients treated with varenicline. BACKGROUND: Abnormal dopaminergic signaling is likely involved in the pathophysiology of TS. Varenicline is a partial α4β2 nicotinic acetylcholine agonist that enhances dopamine release. Therefore, the use of varenicline may influence tics in patients with TS. METHOD: We analyzed and described 2 case studies on patients with significant worsening of tics after treatment with varenicline...
August 14, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28816806/autologous-blood-transfusion-for-postpartum-hemorrhage
#16
Julia A Greenawalt, Denise Zernell
Postpartum hemorrhage (PPH) is a leading contributor to maternal morbidity and mortality in the United States and globally. Although the rate of PPH is generally decreasing nationally, severity of PPH appears to be increasing, potentially related to the various comorbidities associated with women of childbearing age. There is increasing evidence of risks associated with allogeneic blood transfusion, which has historically been the classic therapeutic approach for treatment to PPH. Pregnant women are particularly susceptible to the implications of sensitization to red cell antigens, a common sequela to allogenic blood transfusion...
September 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28816725/effect-of-citalopram-for-the-treatment-of-neurocardiogenic-syncope
#17
Amer N Kadri, Leen Nusairat, Samah Kadri, Ammar Alqaid, Adrian V Hernandez, Nazih N Kadri
BACKGROUND: Neurocardiogenic syncope (NCS) is a common form of syncope. Although selective serotonin reuptake inhibitors and other medications have been used to treat NCS with variable success, there is no consensus regarding a first-line therapy. STUDY QUESTION: To assess the effects of citalopram in NCS and to examine the effect of diagnostic use of the head-up tilt table (HUTT) versus empirical diagnosis on patient outcome. STUDY DESIGN: A retrospective case series of 1000 consecutive patients who were diagnosed with NCS and treated with citalopram...
August 16, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28816711/multiple-drug-intolerant-hypertension
#18
Andrea E Neculau, Liliana M Rogozea, Oana Andreescu, Loredana Jinga, Eleonora A Dinu, Diana Tint
CLINICAL FEATURES: The term multiple drug intolerance (MDI) is attributed to patients who experience adverse drug reactions to more than 3 different classes of medication without a known immunological mechanism. A special attention should be given to multiple drug-intolerant hypertension (MDI-HTN) that is a cause of drop out from treatment and consequent poor blood pressure control. Patients with MDIs account for 2%-5% of all population. The patient we present is a 63-year-old man with third-degree hypertension identified with intolerance to drugs from 4 major classes of antihypertensive medication...
May 26, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28816565/dacryocystectomy-as-a-treatment-of-chronic-dacryocystitis-in-the-elderly
#19
Mariana N Meireles, Magda Mh Viveiros, Roberta Lfs Meneghin, Alicia Galindo-Ferreiro, Mariângela Ea Marques, Silvana A Schellini
To evaluate the dacryocystectomy (DCT) outcomes for chronic dacryocystitis in an elderly population over 70 years old. A retrospective chart review was performed for patients over 70 years old who were diagnosed with chronic dacryocystitis and underwent DCT at the Botucatu School of Medicine, UNESP, Brazil, from 2007 to July 2014. Data were collected about patient demographics, age, gender, previous nasal, or ophthalmic diseases, symptoms related to the lacrimal drainage system preoperatively and postoperatively, signs of enlargement of the lacrimal sac (regurgitation of secretion), and histopathologic evaluation...
August 17, 2017: Orbit
https://www.readbyqxmd.com/read/28816539/non-operative-management-of-differentiated-thyroid-cancer-in-california-a-population-level-analysis-of-29-978-patients
#20
Eric J Kuo, James X Wu, Ning Li, Kyle A Zanocco, Michael W Yeh, Masha J Livhits
OBJECTIVE: There has been increasing interest in active surveillance of papillary thyroid microcarcinoma (mPTC). The objective of this study was to characterize the incidence and outcomes of non-operatively managed differentiated thyroid cancers (DTCs) in California. METHODS: Biopsy-proven DTCs from the California Cancer Registry (CCR) were linked to data from the California Office of Statewide Health Planning and Development (2004-2012). Low-risk tumors were defined as localized disease measuring < 4 cm without extrathyroidal extension, nodal involvement, or distant metastasis...
August 17, 2017: Endocrine Practice
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