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epigenetics,spermatogenesis

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https://www.readbyqxmd.com/read/21540125/epigenetics-spermatogenesis-and-male-infertility
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Singh Rajender, Kelsey Avery, Ashok Agarwal
Epigenetic modifications characterized by DNA methylation, histone modifications, and chromatin remodeling are important regulators in a number of biological processes, including spermatogenesis. Several genes in the testes are regulated through epigenetic mechanisms, indicating a direct influence of epigenetic mechanisms on the process of spermatogenesis. In the present article, we have provided a comprehensive review of the epigenetic processes in the testes, correlation of epigenetic aberrations with male infertility, impact of environmental factors on the epigenome and male fertility, and significance of epigenetic changes/aberrations in assisted reproduction...
May 2011: Mutation Research
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