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Cupping therapy

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https://www.readbyqxmd.com/read/29203116/diagnosis-and-management-of-metastatic-neoplasms-with-unknown-primary
#1
REVIEW
Tilmann Bochtler, Harald Löffler, Alwin Krämer
In cancer of unknown primary (CUP), metastases are clinically and histologically confirmed, but the primary tumor site remains elusive after extensive work-up. CUPs make up for 2-3% of all epithelial malignancies. The two prevailing histologies are adenocarcinomas and undifferentiated carcinomas, whereas squamous cell carcinomas, neuroendocrine carcinomas and rare histologies account for the remaining 10%. The diagnostic work-up in CUP relies strongly on a detailed immunohistological (IHC) analysis in order to characterize the tumor type, nowadays aided by molecular techniques...
November 26, 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/29185802/effects-of-cupping-therapy-in-amateur-and-professional-athletes-systematic-review-of-randomized-controlled-trials
#2
Rhianna Bridgett, Petra Klose, Rob Duffield, Suni Mydock, Romy Lauche
OBJECTIVE: Despite the recent re-emergence of the process of cupping by athletes, supporting evidence for its efficacy and safety remains scarce. This systematic review aims to summarize the evidence of clinical trials on cupping for athletes. METHODS: SCOPUS, Cochrane Library, PubMed, AMED, and CNKI databases were searched from their inception to December 10, 2016. Randomized controlled trials on cupping therapy with no restriction regarding the technique, or cointerventions, were included, if they measured the effects of cupping compared with any other intervention on health and performance outcomes in professionals, semi-professionals, and leisure athletes...
November 29, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29165635/breast-development-in-transwomen-after-one-year-of-cross-sex-hormone-therapy-results-of-a-prospective-multicenter-study
#3
Christel Josefa Maria de Blok, Maartje Klaver, Chantal Maria Wiepjes, Nienke Marije Nota, Annemieke Corine Heijboer, Alessandra Daphne Fisher, Thomas Schreiner, Guy T'Sjoen, Martin den Heijer
Context: Breast development is a key feature of feminization and therefore important to transwomen (male-to-female transgender persons). However, it is not exactly known when breast development starts after initiating cross-sex hormone therapy (CHT) and how much growth may be expected of CHT alone. Objective: To investigate breast development in centimeters and bra cup-sizes in transwomen during their first year of CHT, and whether clinical or laboratory parameters predict the breast development...
November 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29127128/all-sorts-of-tests-only-one-question-an-unexpected-cause-of-hypertension
#4
Sarah Foster, Rachel Foster, Peter Jackson, Soon Song
A 48-year-old woman presented to the Accident and Emergency department with a 4 month history of headaches, nausea and dizziness. She was found to have severe hypertension and hypokalaemia. Extensive investigations did not find any secondary cause for hypertension. The patient was discharged with oral doxazosin therapy which controlled the blood pressure. Before the follow-up appointment at the hypertension clinic, the patient and her husband identified that her headaches coincided with liquorice tea consumption of up to three cups per day...
November 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29122256/cupping-therapy-an-analysis-of-the-effects-of-suction-on-skin-and-the-possible-influence-on-human-health
#5
REVIEW
Duane T Lowe
BACKGROUND: Cupping therapy is a traditional therapy that has been employed worldwide for thousands of years. Despite a lack of quality clinical studies evaluating the efficacy of cupping therapy, its long history and widespread use throughout the world suggests the commonly claimed health benefits should not be completely discounted as without merit. PURPOSE: The goal of this paper is to present the research detailing what is known concerning the effects of suction on skin and underlying tissue, and the reaction of the body to that stimulus...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29049738/a-genome-wide-scan-for-microrna-related-genetic-variants-associated-with-primary-open-angle-glaucoma
#6
Mohsen Ghanbari, Adriana I Iglesias, Henriët Springelkamp, Cornelia M van Duijn, M Arfan Ikram, Abbas Dehghan, Stefan J Erkeland, Caroline C W Klaver, Magda A Meester-Smoor
Purpose: To identify microRNAs (miRNAs) involved in primary open-angle glaucoma (POAG), using genetic data. MiRNAs are small noncoding RNAs that posttranscriptionally regulate gene expression. Genetic variants in miRNAs or miRNA-binding sites within gene 3'-untranslated regions (3'UTRs) are expected to affect miRNA function and contribute to disease risk. Methods: Data from the recent genome-wide association studies on intraocular pressure, vertical cup-to-disc ratio (VCDR), cupa area and disc area were used to investigate the association of miRNAs with POAG endophenotypes...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29045506/clinical-and-molecular-characterization-of-patients-with-cancers-of-unknown-primary-in-the-modern-era
#7
A M Varghese, A Arora, M Capanu, N Camacho, H H Won, A Zehir, J Gao, D Chakravarty, N Schultz, D S Klimstra, M Ladanyi, D M Hyman, D B Solit, M F Berger, L B Saltz
Background: On the basis of historical data, patients with cancers of unknown primary (CUP) are generally assumed to have a dismal prognosis with overall survival of less than one year. Treatment is typically cytotoxic chemotherapy guided by histologic features and the pattern of metastatic spread. The purpose of this study was to provide a clinical and pathologic description of patients with CUP in the modern era, to define the frequency of clinically actionable molecular alterations in this population, to determine how molecular testing can alter therapeutic decisions, and to investigate novel uses of next generation sequencing in the evaluation and treatment of patients with CUP...
September 26, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29044062/changing-epidemiology-of-neovascular-glaucoma-from-2002-to-2012-at-king-khaled-eye-specialist-hospital-saudi-arabia
#8
Abdullah Al-Bahlal, Rajiv Khandekar, Khalid Al Rubaie, Tariq Alzahim, Deepak P Edward, Igor Kozak
PURPOSE: The aim is to present the incidence and determinants of neovascular glaucoma (NVG) in Saudi Arabia. METHODS: A retrospective review of NVG cases (2002-2012) was included to estimate the incidence. The determinants included gender, age, comorbidities, lens status, type of NVG, and visual acuity on presentation. The impact of antiangiogenic therapy on NVG incidence was studied. RESULTS: We studied 597 eyes with NVG. The incidence was 6...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28977975/prognostic-clinicopathologic-factors-in-carcinoma-of-unknown-primary-origin-a-study-of-106-consecutive-cases
#9
Junjeong Choi, Ji Hae Nahm, Sang Kyum Kim
A heterogeneous group of cancers for which the site of origin remains occult after detailed investigations is defined as carcinomas of unknown primary origin (CUPs). Because patients with CUP have a dismal prognosis, we have analyzed CUPs to highlight the implication of clinicopathologic factors related with patient survival. A total of 106 consecutive cases of CUP were collected. A two-step strategy of immunohistochemistry to assess CUPs according NCCN Guidelines is used to separate carcinomatous tumors and subtype carcinomas...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28946531/the-effect-of-cupping-therapy-for-low-back-pain-a-meta-analysis-based-on-existing-randomized-controlled-trials
#10
Yun-Ting Wang, Yong Qi, Fu-Yong Tang, Fei-Meng Li, Qi-Huo Li, Chang-Peng Xu, Guo-Ping Xie, Hong-Tao Sun
BACKGROUND: LBP is one of the most common symptoms with high prevalence throughout the world. Conflicting conclusions exist in RCTs on cupping for LBP. OBJECTIVE: To assess the effects and safety of cupping for the patients with LBP. METHODS: Pubmed, Cochrane Library databases, and Embase database were electronically researched. RCTs reporting the cupping for the patients with LBP were included. The meta-analysis was conducted using Review Manager software (version 5...
June 2, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28915876/changes-in-trust-and-the-use-of-korean-medicine-in-south-korea-a-comparison-of-surveys-in-2011-and-2014
#11
COMPARATIVE STUDY
Soohyun Kwon, Shinhee Heo, Dongjun Kim, Seunghyun Kang, Jong-Min Woo
BACKGROUND: Korean medicine (KM) has been widely used in Korea. This study aimed to assess the general perceptions of KM, to investigate the patterns of its usage in 2014, and to compare the results with those of an earlier survey from 2011. METHODS: A cross-sectional study was conducted with 1000 Korean people. The questionnaire included items regarding trust in KM, reasons for distrust of KM, and visit frequency to KM clinics. This study used methods consistent with those of a 2011 survey to examine changes in attitudes over 3 years...
September 16, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28817383/combined-influence-of-ct-random-noise-and-hu-rsp-calibration-curve-nonlinearities-on-proton-range-systematic-errors
#12
S Brousmiche, K Souris, J Orban de Xivry, J A Lee, B Macq, J Seco
Proton range random and systematic uncertainties are the major factors undermining the advantages of proton therapy, namely, a sharp dose falloff and a better dose conformality for lower doses in normal tissues. The influence of CT artifacts such as beam hardening or scatter can easily be understood and estimated due to their large-scale effects on the CT image, like cupping and streaks. In comparison, the effects of weakly-correlated stochastic noise are more insidious and less attention is drawn on them partly due to the common belief that they only contribute to proton range uncertainties and not to systematic errors thanks to some averaging effects...
October 12, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28779923/cupping-therapy-for-treating-knee-osteoarthritis-the-evidence-from-systematic-review-and-meta-analysis
#13
REVIEW
Jin-Quan Li, Wen Guo, Ze-Gan Sun, Qing-Song Huang, En Yeong Lee, Ying Wang, Xiao-Dong Yao
OBJECTIVE: Cupping therapy is widely used in East Asia, the Middle East, or Central and North Europe to manage the symptom of knee osteoarthritis (KOA). The purpose of this systematic review was to evaluate the available evidence from randomized controlled trials (RCTs) of cupping therapy for treating patients with KOA. METHODS: The following databases were searched from their inception until January 2017: PubMed, Embase, the Cochrane Central Register of Controlled Trials and four Chinese databases [WanFang Med Database, Chinese BioMedical Database, Chinese WeiPu Database, and China National Knowledge Infrastructure (CNKI)]...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28779915/cupping-regulates-local-immunomodulation-to-activate-neural-endocrine-immune-worknet
#14
Yang Guo, Bo Chen, Dong-Qiang Wang, Ming-Yue Li, Calista Hui-Min Lim, Yi Guo, Zelin Chen
Research on cupping therapy is lacking at home and abroad. However, cupping and acupuncture therapy are both surface stimulation therapies. This paper suggests the mechanism of cupping therapy and proposes that the same mechanism underlies both cupping and acupuncture therapy. The microenvironment is changed when stimulating the surface of the skin, and physical signals transform into biological signals, which also interact with each other in the body. These signalling cascades activate the neuroendocrine-immune system, which produces the therapeutic effect...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28770000/cupping-therapy-versus-acupuncture-for-pain-related-conditions-a-systematic-review-of-randomized-controlled-trials-and-trial-sequential-analysis
#15
REVIEW
Ya-Jing Zhang, Hui-Juan Cao, Xin-Lin Li, Xiao-Ying Yang, Bao-Yong Lai, Guo-Yang Yang, Jian-Ping Liu
BACKGROUND: Both cupping therapy and acupuncture have been used in China for a long time, and their target indications are pain-related conditions. There is no systematic review comparing the effectiveness of these two therapies. OBJECTIVES: To compare the beneficial effectiveness and safety between cupping therapy and acupuncture for pain-related conditions to provide evidence for clinical practice. METHODS: Protocol of this review was registered in PROSPERO (CRD42016050986)...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28761205/pain-relief-with-wet-cupping-therapy-in-rats-is-mediated-by-heat-shock-protein-70-and-%C3%A3-endorphin
#16
Imam Subadi, Boya Nugraha, Hening Laswati, Harjanto Josomuljono
BACKGROUND: Wet cupping therapy is a complementary therapy in pain management. The mechanism of this therapy, however, needs further elucidation. Cells injured by wet cupping therapy seem to stimulate the expression of heat shock protein 70 (HSP70). Its benefit in pain reduction could be mediated by the expression of ß-endorphin. This study aimed at determining the correlation between HSP70 and ß-endorphin after wet cupping therapy. METHODS: Sixteen male Wistar rats were divided into control (CG; n=8) and treatment (TG; n=8) groups...
July 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28737431/the-analysis-of-pneumatic-atomization-of-newtonian-and-non-newtonian-fluids-for-different-medical-nebulizers
#17
Marek Ochowiak, Magdalena Matuszak, Sylwia Włodarczak
OBJECTIVE: The article contains results of the experimental studies on atomization process of inhaled drugs and aqueous solutions of glycerol with aqueous solutions of glycerol polyacrylamide (Rokrysol WF1) in pneumatic nebulizers. In experiments, the different concentration of aqueous solutions of glycerol polyacrylamide have been tested. In addition, the effect of nebulizer design on atomization process has been determined. The one of the main elements of medical pneumatic nebulizer is nebulizer cup...
December 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28695912/targeted-therapy-ctdna-identified-in-patients-with-cup
#18
Peter Sidaway
No abstract text is available yet for this article.
September 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/28687563/axitinib-treatment-in-advanced-rai-resistant-differentiated-thyroid-cancer-dtc-and-refractory-medullary-thyroid-cancer-mtc
#19
Jaume Capdevila, José Manuel Trigo, Javier Aller, José Luís Manzano, Silvia García Adrián, Carles Zafón Llopis, Òscar Reig, Uriel Bohn, Teresa Ramón Y Cajal, Manuel Duran-Poveda, Beatriz González Astorga, Ana López-Alfonso, Javier Medina Martínez, Ignacio Porras, Juan Jose Reina, Nuria Palacios, Enrique Grande, Elena Cillán, Ignacio Matos, Juan Jose Grau
BACKGROUND: Axitinib, an antiangiogenic multikinase inhibitor (MKI), was evaluated in the compassionate use programme (CUP) in Spain (October 2012-November 2014). SUBJECTS AND METHODS: 47 patients with advanced radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC, n = 34) or medullary thyroid cancer (MTC, n = 13) with documented disease progression were treated with axitinib 5 mg b.i.d. The primary efficacy endpoint was objective response rate (ORR) by Response Evaluation Criteria In Solid Tumors (RECIST) v1...
October 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28680840/clinical-outcomes-in-patients-with-cancer-of-unknown-primary-site-treated-by-gastrointestinal-oncologists
#20
Sakiko Yamane, Chikatoshi Katada, Satoshi Tanabe, Mizutomo Azuma, Kenji Ishido, Takafumi Yano, Takuya Wada, Akinori Watanabe, Natsuko Kawanishi, Yasuaki Furue, Yuki Kondo, Shouko Komori, Hiromichi Ishiyama, Kazushige Hayakawa, Wasaburo Koizumi
OBJECTIVE: To evaluate the clinical outcomes in patients with cancer of an unknown primary site (CUP), who were treated by gastrointestinal oncologists. METHODS: We retrospectively studied 29 patients with CUP who were presented at the Department of Gastroenterology, Kitasato University Hospital from October 2005 to October 2013, and were treated by the gastrointestinal oncologists. The patients were divided into two groups, namely chemotherapy group and symptomatic therapy group, and the clinical characteristics and survival times were compared...
March 2017: Journal of Translational Internal Medicine
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