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https://www.readbyqxmd.com/read/29915500/evaluation-of-wet-cupping-therapy-on-the-arterial-and-venous-blood-parameters-in-healthy-arabian-horses
#1
Turke Shawaf, Wael El-Deeb, Jamal Hussen, Mahmoud Hendi, Shahab Al-Bulushi
Aim: Recently, the complementary therapies such as cupping and acupuncture are being used in veterinary medicine. This research was carried out to determine the effects of wet cupping therapy (Hijama) on the hematological and the biochemical parameters in the healthy Arabian horses for the first time. Materials and Methods: In this study, seven clinically healthy Arabian horses were randomly selected. Four points on the animal body were selected to perform the cupping therapy...
May 2018: Veterinary World
https://www.readbyqxmd.com/read/29785195/combined-therapies-of-modified-taiyi-miraculous-moxa-roll-and-cupping-for-patients-with-lumbar-intervertebral-disc-herniation
#2
Chunyue Cai, Yuefeng Gong, Dayong Dong, Jinbiao Xue, Xiaoting Zheng, Zhangfeng Zhong, Jialong Shao, Daguo Mi
Lumbar intervertebral disc herniation is a kind of syndrome caused by stimulation or pressure of nerve root and cauda equina due to intervertebral disc disorder, fibrous ring rupture, and pulpiform nucleus protrusion. Application of traditional Chinese medicine (TCM) including acupuncture therapy and cupping therapy is unique and effective treatment for lumbar intervertebral disc herniation in China. Hence, we try to investigate the combined clinical efficacy of modified Taiyi miraculous moxa roll and cupping therapy on patients with lumbar intervertebral disc herniation...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29751335/the-current-evidence-for-a-biomarker-based-approach-in-cancer-of-unknown-primary
#3
REVIEW
Elie El Rassy, Nicholas Pavlidis
Cancer of unknown primary (CUP) accounts for the seventh to eighth most frequently diagnosed cancer yet its prognosis remains poor with conventional chemotherapy. The spectrum of therapeutic management includes both locoregional and systemic therapy and should intend to offer optimal benefit to favorable CUP patients and palliative care to unfavorable cases. The recent molecular advances have revolutionized the armamentarium of cancer treatments though a biomarker-based approach. Unfortunately, solid data in CUP is lacking in the absence of a CUP-specific driver molecular signature...
June 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29732332/case-report-of-a-pustular-dermatitis-outbreak-in-sheep-clinical-and-food-safety-considerations
#4
Mariana Roccaro, Silvia Piva, Alessandra Scagliarini, Federica Giacometti, Andrea Serraino, Giuseppe Merialdi, Matteo Frasnelli, Angelo Romano, Alberto Bellio, Lucia Decastelli, Angelo Peli
The objective of this report is to describe an outbreak of pustular dermatitis in a flock of about 200 sheep, its clinical evolution and food safety implications. The onset of the symptoms was sudden and the lesions spread very quickly from ewe to ewe, so that in about 3 days almost all of the lactating sheep were stricken. Pustules from 5 different animals, six milk samples, two cheese samples, teat cup samples from the milking machine and farmer's hands were analysed. A pure culture of Staphylococcus aureus , producing staphylococcal enterotoxin (SE) C, was isolated from pustules...
March 31, 2018: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/29713497/patient-derived-orthotopic-xenograft-models-for-cancer-of-unknown-primary-precisely-distinguish-chemotherapy-and-tumor-targeting-s-typhimurium-a1-r-is-superior-to-first-line-chemotherapy
#5
Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Kei Kawaguchi, Sang Nam Yoon, Zhiying Zhang, Kentaro Igarashi, Sahar Razmjooei, Sintawat Wangsiricharoen, Takashi Murakami, Yunfeng Li, Scott D Nelson, Tara A Russell, Arun S Singh, Yukihiko Hiroshima, Masashi Momiyama, Ryusei Matsuyama, Takashi Chishima, Shree Ram Singh, Itaru Endo, Fritz C Eilber, Robert M Hoffman
Cancer of unknown primary (CUP) is a recalcitrant disease with poor prognosis because it lacks standard first-line therapy. CUP consists of diverse malignancy groups, making personalized precision therapy essential. The present study aimed to identify an effective therapy for a CUP patient using a patient-derived orthotopic xenograft (PDOX) model. This paper reports the usefulness of the PDOX model to precisely identify effective and ineffective chemotherapy and to compare the efficacy of S. typhimurium A1-R with first-line chemotherapy using the CUP PDOX model...
2018: Signal Transduction and Targeted Therapy
https://www.readbyqxmd.com/read/29682150/positive-effect-of-acupuncture-and-cupping-in-infertility-treatment
#6
Jun-Xiang Wang, Yang Yang, Yue Song, Liang-Xiao Ma
Background: Infertility is clinically defined as the failure to conceive after 12 months of unprotected sexual intercourse. Organic disorders and lifestyle factors are highly associated with infertility. Generally, acupuncture and its related methods can be applied for treating infertility, according to the theory of Traditional Chinese Medicine. Successful cases of acupuncture-treated infertility without concomitant use of any medication are rare. This article presents a case of an infertile woman having a favorable response to acupuncture treatment...
April 1, 2018: Medical Acupuncture
https://www.readbyqxmd.com/read/29670363/long-term-survival-with-transarterial-chemoembolization-and-radioembolization-in-a-patient-with-cancers-of-unknown-primary
#7
Gokmen Aktas, Tulay Kus, Taylan Metin, Selim Kervancioglu, Umut Elboga
Cancers of unknown primary (CUP) are histologically proven metastatic malignant tumors without an identified primary site before treatment. The common characteristics are early dissemination, lower response to chemotherapy and poor prognosis with short life expectancy. Treatment was directed according to the presence of localized or disseminated disease. The most frequent site of metastasis is the liver, which is a suitable target organ for arterial-directed therapies. We report a case of 53-year-old woman who was diagnosed with CUP and suspected with intracellular cholangiocellular carcinoma (ICC), presented with a very large, unresectable, chemotherapy-refractory hepatic mass and treated with transarterial chemoembolization and transarterial radioembolization and surprisingly followed for 48 months with minimally progressive and stable disease...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29657501/evaluation-of-bloodletting-cupping-therapy-in-the-management-of-hypertension
#8
Moawia M Al-Tabakha, Farah Tariq Sameer, Mai Hafiz Saeed, Rahaf Montaser Batran, Nada Tarek Abouhegazy, Alaa A Farajallah
Background: Bloodletting cupping therapy (Hijama) is a traditional alternative medicine practiced in different cultures. Claims about the therapeutic efficacy of Hijama in hypertension are contradictory. The aim of this project was to determine if Hijama therapy is beneficial in the treatment of patients with hypertension. Materials and Methods: In this retrospective study, 60 files for patients treated for hypertension, aged 40-60 years and whose systolic blood pressure (SBP) is at least 140mm Hg, were used...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29656965/total-hip-arthroplasty-for-periacetabular-metastatic-disease-an-original-technique-of-reconstruction-according-to-the-harrington-classification
#9
Julien Wegrzyn, Matthieu Malatray, Turki Al-Qahtani, Vincent Pibarot, Cyrille Confavreux, Gilles Freyer
BACKGROUND: Periacetabular metastatic disease requires complex acetabular reconstruction. The complication rate for these frail patients is high. Various cement-rebar reinforced techniques allowing cemented total hip arthroplasty (THA) have been described. The optimal procedure has not yet been identified. METHODS: A continuous series of 131 THAs performed in 126 patients with periacetabular metastatic disease was prospectively included in this study. After bone metastasis curettage and cementation, an original technique of acetabular reconstruction was performed using a dual mobility cup cemented into an acetabular reinforcement device (ie, Kerboull cross-plate or Burch-Schneider antiprotrusio cage) according to the Harrington classification...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29651651/interactions-of-coffee-consumption-and-postmenopausal-hormone-use-in-relation-to-breast-cancer-risk-in-uk-biobank
#10
Lusine Yaghjyan, Shannan Rich, Liang Mao, Volker Mai, Kathleen M Egan
PURPOSE: We investigated the association of coffee consumption with postmenopausal breast cancer risk, overall and by the status of postmenopausal hormone therapy (PMH). METHODS: This study included 126,182 postmenopausal women (2,636 with breast cancer and 123,546 without) from UK Biobank. Cancer diagnoses were ascertained through the linkage to the UK National Health Service Central Registers. Information on breast cancer risk factors and coffee consumption was collected at baseline and updated during follow-up...
June 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29623630/the-potential-clinical-and-economic-value-of-primary-tumour-identification-in-metastatic-cancer-of-unknown-primary-tumour-a-population-based-retrospective-matched-cohort-study
#11
Malek B Hannouf, Eric Winquist, Salaheddin M Mahmud, Muriel Brackstone, Sisira Sarma, George Rodrigues, Peter K Rogan, Jeffrey S Hoch, Gregory S Zaric
PURPOSE: Several genomic tests have recently been developed to identify the primary tumour in cancer of unknown primary tumour (CUP). However, the value of identifying the primary tumour in clinical practice for CUP patients remains questionable and difficult to prove in randomized trials. OBJECTIVE: We aimed to assess the clinical and economic value of primary tumour identification in CUP using a retrospective matched cohort study. METHODS: We used the Manitoba Cancer Registry to identify all patients initially diagnosed with metastatic cancer between 2002 and 2011...
September 6, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29621151/immunohistochemistry-for-diagnosis-of-metastatic-carcinomas-of-unknown-primary-site
#12
REVIEW
Janick Selves, Elodie Long-Mira, Marie-Christine Mathieu, Philippe Rochaix, Marius Ilié
Immunohistochemistry has become an essential ancillary examination for the identification and classification of carcinomas of unknown primary site (CUPs). Over the last decade, the diagnostic accuracy of organ- or tumour-specific immunomarkers and the clinical validation of effective immunohistochemical panels has improved significantly. When dealing with small sample sizes, diagnostic accuracy is crucial, particularly in the current era of targeted molecular and immune-based therapies. Effective systematic use of appropriate immunohistochemical panels enables accurate classification of most of the undifferentiated carcinomas as well as careful preservation of tissues for potential molecular or other ancillary tests...
April 5, 2018: Cancers
https://www.readbyqxmd.com/read/29587959/cup-syndrome-metastatic-malignancy-with-unknown-primary-tumor
#13
Gregor Zaun, Martin Schuler, Ken Herrmann, Andrea Tannapfel
BACKGROUND: 2-4% of newly diagnosed cases of malignant disease involve cancer of unknown primary (CUP). This mixed entity is one of the 6 most common types of malignant disease in Germany. Highly refined treatment strategies can now be offered to patients with CUP. METHODS: This review is based on pertinent publications retrieved by a selective search in PubMed with an emphasis on articles from the past decade. The current guidelines and recommendations of specialty societies were also considered in the evaluation...
March 9, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29581792/inhaled-immunotherapy-administration-for-lung-cancer-efficient-certainly-possible
#14
Konstantinos Sapalidis, Paul Zarogoulidis, Haidong Huang, Chong Bai, Yuting Wen, Li Wang, Konstantina Boniou, Ilias Karapantzos, Chrysanthi Karapantzou, Michael Karanikas, Vasilis Thomaidis, Christoforos Kosmidis, Chrysanthi Sardeli, Naim Benhassen, Yan-Gao Man, Maria C Florou, Stylianos Mantalovas, Stella Laskou, Dimitris Giannakidis, Charilaos Koulouris, Aikaterini Amaniti, Isaak Kesisoglou, Wolfgang Hohenforst-Schmidt
Lung cancer is still diagnosed at a late stage in most lung cancer patients. Regarding Non-small Cell lung cancer there are novel therapies such as; tyrosine kinase inhibitors and immunotherapy. Currently we have two immunotherapies that can be used either as first-line treatment or second line treatment; pembrolizumab and nivolumab. A third one is being investigated as a combination of immunotherapy; ipilimumab. Aerosol treatment has been investigated for many diseases not only for the lung, but also for systematic diseases...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29571084/comprehensive-analysis-of-cancers-of-unknown-primary-for-the-biomarkers-of-response-to-immune-checkpoint-blockade-therapy
#15
Zoran Gatalica, Joanne Xiu, Jeff Swensen, Semir Vranic
BACKGROUND: Cancer of unknown primary (CUP) accounts for approximately 3% of all malignancies. Avoiding immune destruction is a major cancer characteristic and therapies aimed at immune checkpoint blockade are in use for several specific cancer types. A comprehensive survey of predictive biomarkers to immune checkpoint blockade in CUP were explored in this study. METHODS: About 389 cases of CUP were analysed for mutations in 592 genes and 52 gene fusions using a massively parallel DNA sequencing platform (next-generation sequencing [NGS])...
May 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29485257/pediatric-melanoma-update
#16
Lindsay McCORMACK, Elena B Hawryluk
Pediatric melanoma is a rare disease that affects approximately 6 out of every one million children and accounts for 1-4 percent of all melanomas. This article reviews the epidemiology, etiology, diagnosis, treatment and prognosis of pediatric melanoma - with particular attention to recent updates in the literature. While awareness of melanoma increases among the general population, recent data suggest stable and even declining incidence rates among certain pediatric populations. Studies have examined clinical features and presentations of melanoma among the pediatric population and the conventional ABCDE criteria used to diagnosis adult melanoma may not be entirely appropriate for pediatric melanoma; as such, additional pediatric-ABCD and CUP criteria have been proposed...
February 26, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29473359/-comparison-of-the-effects-of-the-intervention-with-electric-thermal-bian-stone-and-air-suction-cup-on-blood-perfusion-at-meridian-points
#17
Pengna Zhao, Yanping Wang, Feifei Gu, Chaozheng Li, Yulong Wei, Guangjun Wang, Weibo Zhang
OBJECTIVE: To observe the impacts of the intervention with electric thermal bian stone and air suction cup on blood perfusion (BP) at meridian points and explore the approach of accurate measurement and regulation of meridian qi and blood balance in "precise acupuncture". METHODS: The laser Doppler line scanner (LDLS) was used to measure BP at bilateral yua n-primary points at the pericardium meridian, the triple energizer meridian, the gallbladder meridian and the liver meridian (small cycle of jueyin to shaoyang meridians) at 31 healthy receptors...
February 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29461690/numerical-research-on-the-biomechanical-behaviour-of-braided-stents-with-different-end-shapes-and-stent-oesophagus-interaction
#18
Xiao-Yu Ni, Yan-Hong Zhang, Hai-Xia Zhao, Chang-Wang Pan
Quasi-static and dynamic numerical analyses are carried out by referring to computational models of commercial self-expandable braided stents with 3 commonly used end shapes, to evaluate the influence of different end shapes of stent on the biomechanical interaction between stent and oesophagus. The end shape has no influence on the equivalent stress, but has a great influence on the contact stress in the narrowest zone of the oesophagus-neoplasm system. However, the end shapes have significant effect on the equivalent stress and the contact stress in the healthy area of the oesophagus in contact with the stent ends...
February 20, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29458925/is-cupping-blister-harmful-a-proteomical-analysis-of-blister-fluid-induced-by-cupping-therapy-and-scald
#19
Zhidan Liu, Chunlan Chen, Xiaoyan Li, Chuang Zhao, Zunyuan Li, Wei Liang, Yufang Lin
OBJECTIVE: Cupping therapy has a long history in traditional medicine especially in Asian countries. It was controversial whether cupping induced blisters are beneficial to healing effects, and the formation and content in the blisters remain unexplored. We aimed to identify and compare the molecular components of the blister fluid from the cupping therapy and the scalds to explore the necessary of inducing cupping induced blisters. METHODS: Fluid sample of blisters from fifteen patients receiving cupping therapy (Cupping group) and scald burns (Scald group) were collected in this study...
February 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29456893/the-effect-of-supragingival-glycine-air-polishing-on-periodontitis-during-maintenance-therapy-a-randomized-controlled-trial
#20
Hongye Lu, Lu He, Yibing Zhao, Huanxin Meng
Background: Glycine air polishing has been proved to be safe, comfortable and time-saving. Whether it could substitute ultrasonic scaling to remove dental plaque biofilm during periodontal maintenance remains unclear. The purposes of this study were to evaluate the effect of supragingival glycine air polishing (SGAP) on the subgingival periodontal pathogens during maintenance therapy and to check the association of periodontal pathogens and clinical parameters. Methods: Twenty-three chronic periodontitis patients during their maintenance therapy were enrolled in the 12-week study...
2018: PeerJ
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