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Local anaesthetics

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https://www.readbyqxmd.com/read/29666908/intravenous-local-anaesthetic-compared-with-intraperitoneal-local-anaesthetic-in-abdominal-surgery-a-systematic-review
#1
REVIEW
Wiremu S MacFater, Weisi Xia, Ahmed Barazanchi, Bruce Su'a, Darren Svirskis, Andrew G Hill
INTRODUCTION: Modern perioperative care strategies aim to optimise perioperative care by reducing the body's stress response to surgery. A major facet of optimising an abdominal surgery analgesia programme is using a multimodal opioid sparing approach. Local anaesthetics have shown promise and there has been considerable research into the most effective route for their administration. This review aims to determine if there is a difference in analgesic efficacy between intraperitoneal local anaesthetic (IPLA) and intravenous local anaesthetic (IVLA)...
April 17, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29664158/spread-of-injectate-around-hip-articular-sensory-branches-of-the-femoral-nerve-in-cadavers
#2
N D Nielsen, M Greher, B Moriggl, R Hoermann, T D Nielsen, J Børglum, T F Bendtsen
BACKGROUND: Anatomical knowledge dictates that regional anaesthesia after total hip arthroplasty requires blockade of the hip articular branches of the femoral and obturator nerves. A direct femoral nerve block increases the risk of fall and impedes mobilisation. We propose a selective nerve block of the hip articular branches of the femoral nerve by an ultrasound-guided injection in the plane between the iliopsoas muscle and the iliofemoral ligament (the iliopsoas plane). The aim of this study was to assess whether dye injected in the iliopsoas plane spreads to all hip articular branches of the femoral nerve...
April 17, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29657082/horner-s-syndrome-following-obstetric-neuraxial-blockade-a-systematic-review-of-the-literature
#3
D J Chambers, K Bhatia
Horner's syndrome is a rarely reported complication of neuraxial blockade. In obstetric practice, the neurological signs of Horner's syndrome may cause anxiety amongst patients and healthcare staff, but more importantly may herald the onset of maternal hypotension. Medline, CINAHL, and EMBASE databases were searched to identify cases of Horner's syndrome following obstetric neuraxial blockade. Anaesthetic technique, clinical features, anaesthetic management of the Horner's syndrome and time to resolution were assessed...
March 17, 2018: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29652895/complications-after-transcatheter-aortic-valve-implantation-using-transfemoral-and-transapical-approach-in-general-anaesthesia
#4
Fabian Würschinger, Sigrid Wittmann, Sophia Goldfuß, Nina Zech, Kurt Debl, Michael Hilker, Bernhard M Graf, York A Zausig
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure used to treat degenerative heart valve disease. The implantation requires a highly specific and interdisciplinary management approach. Currently, TAVI is performed with the patient under local or general anaesthesia. METHODS: This study was a retrospective analysis of all TAVI procedures performed at the University Hospital of Regensburg between January 2009 and July 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29644990/distraction-technique-for-pain-reduction-in-peripheral-venous-catheterization-randomized-controlled-trial
#5
Ihor Balanyuk, Giuseppina Ledonne, Marco Provenzano, Roberto Bianco, Cristina Meroni, Paola Ferri, Loris Bonetti
BACKGROUND AND AIM OF THE WORK: Procedural pain during Peripheral Venous Catheterization (PVC) is a significant issue for patients. Reducing procedure-induced pain improves the quality of care and reduces patient discomfort. We aimed to compare a non-pharmacological technique (distraction) to anaesthetic cream (EMLA) for the reduction of procedural pain during PVC, in patients undergoing Computerized Tomography (CT) or Nuclear Magnetic Resonance (NMR) with contrast. METHODS: This is a Prospective, Randomized Controlled Trial...
February 21, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29628319/facial-nerve-palsy-and-laryngospasm-as-a-complication-of-local-anaesthesia-during-adenotonsillectomy
#6
Michał Lubszczyk, Anna Łuczyńska-Sopel, Dariusz Polaczkiewicz
Tonsil surgeries are the most frequently performed surgical procedures in ENT departments. We would like to present the case of a 5-year-old patient who suffered from unilateral peripheral facial nerve palsy and laryngeal spasm following adenotonsillectomy. Paresis was observed immediately after the transfer of the patient to the postoperative room. The activity of facial muscles was restored within 2 hours from the beginning of the surgery. We assume that this was the direct effect of an anaesthetic on the extracranial processes of the facial nerve...
April 5, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29627630/awake-intradural-spinal-tumour-resection
#7
Anan Shtaya, Chan Bao Luong, Erlick Pereira
BACKGROUND: Meningioma is a common slow growing spinal tumour with a predilection for intradural occurrence. Patients usually present with pain followed by ataxia and sensory and sphincter problems. The gold standard treatment in these cases is gross total microsurgical resection under general anaesthesia. However, there exist high anaesthetic risk patients unsuitable for general anaesthesia. Performing spinal surgeries under local anaesthesia and sedation has been reported albeit rarely for mostly minimally invasive procedures but not for open intradural pathologies...
April 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29622413/use-of-genitofemoral-and-ilioinguinal-and-iliohypogastric-nerve-block-during-orchiectomy-in-a-post-lung-transplant-patient-a-case-report
#8
B A Rivas Rivero, A Mira Puerto, J Cuenca
The case is presented of a post-lung transplant patient, ASA III, proposed for orchiectomy due to testicular cancer. A combination of iliohypogastric (ILH), ilioinguinal (ILI) and genitofemoral (GF) nerve block together with sedation was used as anaesthetic technique. The inguinal area received sensory innervation mainly from ILI, ILH and GF nerves. The genital branch of the GF nerve supplies innervation to skin of the anterosuperior portion of the scrotum. When performing the echo-guided block of GF nerve, it is necessary to identify the spermatic cord, and administer the local anaesthetic on the inside and periphery of the cord...
April 2, 2018: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/29618887/comparison-of-ropivacaine-0-75-and-lignocaine-2-with-1-200-000-adrenaline-in-dental-extractions-single-blind-clinical-trial
#9
Vishal Bansal, Deval Kumar, Apoorva Mowar, Avi Bansal
Introduction: The aim of this study was to evaluate the efficacy, safety and clinical acceptability of the local anaesthetic agent ropivacaine 0.75 % in comparison with lignocaine 2 % with adrenaline 1:200,000 in minor oral surgical procedures. Methods: Forty-seven patients, who required bilateral extractions in a single arch, were included in this study. One hundred and sixty-six extractions were performed and all the patients were administered nerve blocks/infiltration...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29618778/dynamic-interaction-of-local-and-transhemispheric-networks-is-necessary-for-progressive-intensification-of-hippocampal-seizures
#10
Fredrik Berglind, My Andersson, Merab Kokaia
The detailed mechanisms of progressive intensification of seizures often occurring in epilepsy are not well understood. Animal models of kindling, with progressive intensification of stimulation-induced seizures, have been previously used to investigate alterations in neuronal networks, but has been obscured by limited recording capabilities during electrical stimulations. Remote networks in kindling have been studied by physical deletions of the connected structures or pathways, inevitably leading to structural reorganisations and related adverse effects...
April 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29611788/c-mac-%C3%A2-videolaryngoscopy-the-anaesthetic-assistant-s-view
#11
Lydia Jones, Kathleen Mulcahy, Jeremy Fox, Tim M Cook, Fiona E Kelly
Although videolaryngoscopy plays a major role in the 2015 Difficult Airway Society guidelines, the impact on anaesthetic assistant working practices and training has not previously been reported. We surveyed anaesthetic assistants in our hospital to document their experience with using the C-MAC© videolaryngoscope (48 practitioners, 100% response rate). Improvements in the following were reported: patient safety 100%; ability to see whether laryngoscopy is difficult 98%; ability to anticipate the 'next step' 98%; team-working and human factors 96%; ability to call a senior anaesthetist more quickly 94%; assessment or adjustment of cricoid force application 92%, understanding of laryngeal anatomy 92%; training in intubation 98%; training in cricoid force application 87%...
April 2018: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29601421/economic-evaluation-of-bilateral-sternal-local-anaesthetic-infusions-via-multi-hole-catheters-after-cardiac-surgery
#12
Charline Mourgues, Arnaud Themista, Vedat Eljezi
No abstract text is available yet for this article.
May 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29582351/comparing-human-peritoneal-fluid-and-phosphate-buffered-saline-for-drug-delivery-do-we-need-bio-relevant-media
#13
Prabhat Bhusal, Jamie Lee Rahiri, Bruce Sua, Jessica E McDonald, Mahima Bansal, Sara Hanning, Manisha Sharma, Kaushik Chandramouli, Jeff Harrison, Georgina Procter, Gavin Andrews, David S Jones, Andrew G Hill, Darren Svirskis
An understanding of biological fluids at the site of administration is important to predict the fate of drug delivery systems in vivo. Little is known about peritoneal fluid; therefore, we have investigated this biological fluid and compared it to phosphate-buffered saline, a synthetic media commonly used for in vitro evaluation of intraperitoneal drug delivery systems. Human peritoneal fluid samples were analysed for electrolyte, protein and lipid levels. In addition, physicochemical properties were measured alongside rheological parameters...
March 26, 2018: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29576125/single-shot-pectoral-plane-pecs-i-and-pecs-ii-blocks-versus-continuous-local-anaesthetic-infusion-analgesia-or-both-after-non-ambulatory-breast-cancer-surgery-a-prospective-randomised-double-blind-trial
#14
P O'Scanaill, S Keane, V Wall, G Flood, D J Buggy
BACKGROUND: Pectoral plane blocks (PECs) are increasingly used in analgesia for patients undergoing breast surgery, and were recently found to be at least equivalent to single-shot paravertebral anaesthesia. However, there are no data comparing PECs with the popular practice of continuous local anaesthetic wound infusion (LA infusion) analgesia for breast surgery. Therefore, we compared the efficacy and safety of PECs blocks with LA infusion, or a combination of both in patients undergoing non-ambulatory breast-cancer surgery...
April 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29569459/a-video-eyeglasses-earphones-system-as-distracting-method-during-dental-treatment-in-children-a-crossover-randomised-and-controlled-clinical-trial
#15
A Garrocho-Rangel, E Ibarra-Gutiérrez, M Rosales-Bérber, R Esquivel-Hernández, V Esparza-Villalpando, A Pozos-Guillén
AIM To evaluate the effectiveness of a Video Eyeglasses/Earphones System (VEES) as distracting device in reducing anxiety in children during dental procedures carried out under local anaesthesia. MATERIALS AND METHODS: In this crossover clinical trial, 36 Frankl scale II and III children aged 5-8 years received different dental procedures in two sessions, with and without the VEES system. In the control visit, they were not exposed to this distraction stimulus, but traditional non-aversive behaviour management was applied...
March 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29569455/laser-labial-frenectomy-a-simplified-and-predictable-technique-retrospective-clinical-study
#16
M Olivi, M D Genovese, G Olivi
AIM: Anomalous maxillary median labial frenum may be associated with undesired effects such as persistence of diastema between anterior teeth or traction of marginal gingiva. The aim of this study was to propose a surgical frenum repositioning technique that is minimally invasive, safe, easy, reproducible, and predictable. Another objective of the study was to identify clinical scenarios that could have indication for labial frenectomy associated with early orthodontic therapy, so as to justify early frenum repositioning in children...
March 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29569452/single-tooth-anaesthesia-a-new-approach-to-the-paediatric-patient-a-clinical-experimental-study
#17
L Giannetti, E Forabosco, E Spinas, D Re, A Murri Dello Diago
AIM: The objective of this study is to assess the efficacy of the STA Wand System with respect to pain and fear reduction in paediatric patients and by using the Single Tooth Anaesthesia (STA) technique. MATERIALS AND METHODS: Patients included children and teenagers between 6 and 17 years of age, who required the administration of local anaesthesia prior to expected treatments. Local anaesthesia was performed by means of the electronic STA Wand System (Milestone scientific...
March 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29567597/a-randomised-field-study-evaluating-the-effectiveness-of-buccal-meloxicam-and-topical-local-anaesthetic-formulations-administered-singly-or-in-combination-at-improving-welfare-of-female-merino-lambs-undergoing-surgical-mulesing-and-hot-knife-tail-docking
#18
Alison Holdhus Small, Danila Marini, Tim Dyall, David Paull, Caroline Lee
This study was a field-based behavioural assessment of the pain responses to surgical mulesing modulated by a buccal formulation of meloxicam (Buccalgesic) and a topical local anaesthetic wound dressing (Tri-Solfen). 20 lambs were randomly allocated to each of: 1) Placebo and sham handled (Sham); 2) Placebo and mulesing (Mules); 3) Buccalgesic and mulesing (Mules+B); 4) Tri-Solfen and mulesing (Mules+T); 5) Placebo, Tri-Solfen and mulesing (Mules+T+P); 6) Buccalgesic, Tri-Solfen and mulesing (Mules+T+B). Lamb behaviour was observed by scan sampling every 15 min for 6 h post mulesing then for 1...
March 8, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29543062/benefits-of-pre-emptive-analgesia-by-local-infiltration-at-day-case-general-anaesthetic-open-inguinal-hernioplasty
#19
R W Radwan, A Gardner, H Jayamanne, B M Stephenson
Introduction The open prosthetic repair of inguinal hernias under local anaesthesia (LA) is well established, with the concept of intraoperative 'pre-emptive analgesia' evolving so that patients are as comfortable as possible. We used a peri-incisional LA solution in patients undergoing day-case inguinal hernioplasty under general anaesthesia (GA) and recorded use of analgesia in the immediate postoperative period. Methods In this observational cohort study, 100 consecutive unselected men underwent open inguinal hernia repair as a day case...
March 15, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29539592/a-field-study-evaluation-of-buccal-meloxicam-and-topical-anaesthetic-at-improving-welfare-of-lambs-undergoing-surgical-mulesing-and-hot-knife-tail-docking
#20
Alison Holdhus Small, Danila Marini, Maxime le Floch, David Paull, Caroline Lee
Mulesing is a painful husbandry procedure commonly used to reduce the risk of breech strike in sheep. This study assessed the behavioural (over 6 h), cortisol, haptoglobin and haematology responses to surgical mulesing plus tail hot knife docking (mulesing); modulated by a buccal meloxicam formulation (Buccalgesic), a topical local anaesthetic wound dressing (Tri-Solfen) or both agents. 24 lambs were allocated to each of: 1) Placebo and sham handled (Sham); 2) Placebo and mulesing (Mules); 3) Buccalgesic and mulesing (Mules + B); 4) Tri-Solfen and mulesing (Mules + T); 5) Placebo, Tri-Solfen and mulesing (Mules + T + P); 6) Buccalgesic, Tri-Solfen and mulesing (Mules + T + B)...
February 28, 2018: Research in Veterinary Science
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