keyword
MENU ▼
Read by QxMD icon Read
search

tumor board

keyword
https://www.readbyqxmd.com/read/28821205/cerebrospinal-fluid-circulating-tumor-cells-a-novel-tool-to-diagnose-leptomeningeal-metastases-from-epithelial-tumors
#1
Xuling Lin, Martin Fleisher, Marc Rosenblum, Oscar Lin, Adrienne Boire, Samuel Briggs, Yevgeniya Bensman, Brenda Hurtado, Larisa Shagabayeva, Lisa M DeAngelis, Katherine S Panageas, Antonio Omuro, Elena I Pentsova
Background: Diagnosis of leptomeningeal metastasis (LM) remains challenging due to low sensitivity of CSF cytology and infrequent unequivocal MRI findings. In a previous pilot study, we showed that rare cell capture technology (RCCT) could be used to detect circulating tumor cells (CTC) in the CSF of patients with LM from epithelial tumors. To establish the diagnostic accuracy of CSF-CTC in the diagnosis of LM, we applied this technique in a distinct, larger cohort of patients. Methods: In this institutional review board-approved prospective study, patients with epithelial tumors and clinical suspicion of LM underwent CSF-CTC evaluation and standard MRI and CSF cytology examination...
September 1, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28817159/treatment-of-unicameral-bone-cysts-of-the-proximal-femur-with-internal-fixation-lessens-the-risk-of-additional-surgery
#2
Benjamin Wilke, Matthew Houdek, Rameshwar R Rao, Michelle S Caird, A Noelle Larson, Todd Milbrandt
Little data exist to guide the treatment of unicameral bone cysts in the proximal femur. Methods of treatment include corticosteroid injections, curettage and bone grafting, and internal fixation. The authors completed a multi-institutional, retrospective review to evaluate their experience with proximal femoral unicameral bone cysts. They posed the following questions: (1) Does internal fixation reduce the risk of further procedures for the treatment of a unicameral bone cyst? (2) Is radiographic healing faster with internal fixation? Following institutional review board approval, the authors conducted a retrospective review of 36 patients treated for a unicameral bone cyst of the proximal femur at their institutions between 1974 and 2014...
August 17, 2017: Orthopedics
https://www.readbyqxmd.com/read/28816956/differential-diagnosis-of-posterior-fossa-brain-tumors-multiple-discriminant-analysis-of-tl-spect-and-fdg-pet
#3
Moritaka Yamauchi, Tomohisa Okada, Tsutomu Okada, Akira Yamamoto, Yasutaka Fushimi, Yoshiki Arakawa, Susumu Miyamoto, Kaori Togashi
This study investigated the combined capability of thallium-201 (Tl)-SPECT and fluorine-18-fluoro-deoxy-glucose (FDG)-PET for differential diagnosis of posterior fossa brain tumors using multiple discriminant analysis.This retrospective study was conducted under approval of the institutional review board. In the hospital information system, 27 patients with posterior fossa intra-axial tumor between January 2009 and June 2015 were enrolled and grouped as the following 7 entities: low grade glioma (LGG) 6, anaplastic astrocytoma (AA) 2, glioblastoma (GBM) 3, medulloblastoma (MB) 3, hemangioblastoma (HB) 6, metastatic tumor (Mets) 3, and malignant lymphoma (ML) 4...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28810954/the-use-of-apremilast-to-treat-psoriasis-during-deployment
#4
Alexandra Rosenberg, Jon Meyerle
Psoriasis is a chronic immune-mediated dermatologic disorder affecting approximately 2% of the general population. Under current U.S. Army regulation, the diagnosis of psoriasis is a bar to enlistment or appointment and, if poorly controlled, is grounds for referral to a Medical Evaluation Board and potential discharge from military service, according to Army Regulation 40-501. However, between 2008 and 2015, over 3,600 soldiers sought care for psoriasis while deployed to combat theaters, indicating that psoriasis remains a significant medical concern in the U...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28806263/18f-dcfbc-prostate-specific-membrane-antigen-targeted-pet-ct-imaging-in-localized-prostate-cancer-correlation-with-multiparametric-mri-and-histopathology
#5
Baris Turkbey, Esther Mena, Liza Lindenberg, Stephen Adler, Sandra Bednarova, Rose Berman, Anita T Ton, Yolanda McKinney, Philip Eclarinal, Craig Hill, George Afari, Sibaprasad Bhattacharyya, Ronnie C Mease, Maria J Merino, Paula M Jacobs, Bradford J Wood, Peter A Pinto, Martin G Pomper, Peter L Choyke
PURPOSE: To assess the ability of (N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-F-fluorobenzyl-L-cysteine) (F-DCFBC), a prostate-specific membrane antigen-targeted PET agent, to detect localized prostate cancer lesions in correlation with multiparametric MRI (mpMRI) and histopathology. METHODS: This Health Insurance Portability and Accountability Act of 1996-compliant, prospective, institutional review board-approved study included 13 evaluable patients with localized prostate cancer (median age, 62...
August 12, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28799842/midterm-safety-and-efficacy-of-irreversible-electroporation-of-malignant-liver-tumors-located-close-to-major-portal-or-hepatic-veins
#6
Martina Distelmaier, Alexandra Barabasch, Philipp Heil, Nils A Kraemer, Peter Isfort, Sebastian Keil, Christiane K Kuhl, Philipp Bruners
Purpose To investigate the efficacy and safety of irreversible electroporation (IRE) in the treatment of hepatic tumors not suitable for thermal ablation (radiofrequency ablation [RFA] or microwave ablation). Materials and Methods This was an institutional review board-approved prospective study in 29 patients (15 men, 14 women; mean age, 63 years ± 12 [standard deviation]) with 43 primary (n = 8) or secondary (n = 35) malignant liver tumors who underwent computed tomography (CT)-guided IRE. All target tumors were located immediately adjacent to major hepatic veins, portal veins, or both; thus, they were not considered suitable for RFA or microwave ablation...
August 11, 2017: Radiology
https://www.readbyqxmd.com/read/28774861/multidisciplinary-tumor-board-decision-making-for-postoperative-radiotherapy-in-thymic-epithelial-tumors-insights-from-the-rythmic-prospective-cohort
#7
Clémence Basse, Sébastien Thureau, Suzanna Bota, Eric Dansin, Pascal-Alexandre Thomas, Eric Pichon, Hervé Lena, Carole Massabeau, Christelle Clement-Duchene, Gilbert Massard, Virginie Westeel, Xavier Quantin, Youssef Oulkhouir, Serge Danhier, Delphine Lerouge, Ronan Tanguy, François Thillays, Cécile Le Pechoux, Bernard Dubray, Luc Thiberville, Benjamin Besse, Nicolas Girard
BACKGROUND: Thymic Epithelial Tumors (TET) are rare intrathoracic malignancies for which surgery represents the mainstay of the treatment. Current practice for postoperative radiotherapy (PORT) is highly variable and there is a lack of prospective, high level evidence. RYTHMIC is the nationwide network for TET in France established in 2012, which prospectively collects data for all TET patients, for whom management is discussed at a national multidisciplinary tumor board (MTB). We assessed whether postoperative radiotherapy (PORT) decisions at the MTB were in accordance with RYTHMIC guidelines, and ultimately implemented in patients...
July 31, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28767674/versatile-ion-s5xl-sequencer-for-targeted-next-generation-sequencing-of-solid-tumors-in-a-clinical-laboratory
#8
Meenakshi Mehrotra, Dzifa Yawa Duose, Rajesh R Singh, Bedia A Barkoh, Jawad Manekia, Michael A Harmon, Keyur P Patel, Mark J Routbort, L Jeffrey Medeiros, Ignacio I Wistuba, Rajyalakshmi Luthra
BACKGROUND: Next generation sequencing based tumor tissue genotyping involves complex workflow and a relatively longer turnaround time. Semiconductor based next generation platforms varied from low throughput Ion PGM to high throughput Ion Proton and Ion S5XL sequencer. In this study, we compared Ion PGM and Ion Proton, with a new Ion S5XL NGS system for workflow scalability, analytical sensitivity and specificity, turnaround time and sequencing performance in a clinical laboratory. METHODS: Eighteen solid tumor samples positive for various mutations as detected previously by Ion PGM and Ion Proton were selected for study...
2017: PloS One
https://www.readbyqxmd.com/read/28765978/imaging-features-of-hepatocellular-carcinoma-compared-to-intrahepatic-cholangiocarcinoma-and-combined-tumor-on-mri-using-liver-imaging-and-data-system-li-rads-version-2014
#9
Natally Horvat, Ines Nikolovski, Niamh Long, Scott Gerst, Jian Zheng, Linda Ma Pak, Amber Simpson, Junting Zheng, Marinela Capanu, William R Jarnagin, Lorenzo Mannelli, Richard Kinh Gian Do
PURPOSE: To evaluate the prevalence of major and ancillary imaging features from liver imaging reporting and data systems (LI-RADS) version 2014 and their interreader agreement when comparing hepatocellular carcinoma (HCC) to intrahepatic cholangiocarcinoma (ICC) and combined tumor (cHCC-CC). METHODS: The Institutional Review Board approved this HIPAA-compliant retrospective study and waived the requirement for patients' informed consent. Patients with resected HCC (n = 51), ICC (n = 40), and cHCC-CC (n = 11) and available pre-operative contrast-enhanced MRI were included from 2000 to 2015...
August 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28763434/comparison-of-3-hypertonic-saline-and-20-mannitol-for-reducing-intracranial-pressure-in-patients-undergoing-supratentorial-brain-tumor-surgery-a-randomized-double-blind-clinical-trial
#10
Achmet Ali, Aylin Tetik, Pulat A Sabanci, Demet Altun, Nukhet Sivrikoz, Taner Abdullah, Aydin Aydoseli, Altay Sencer, Ibrahim O Akinci
BACKGROUND: In the present study, we hypothesized that 3% hypertonic saline (HS) is more effective than 20% mannitol to reduce intracranial pressure (ICP) and to modify brain bulk in patients undergoing an elective supratentorial craniotomy. MATERIALS AND METHODS: After institutional review board approval, patients scheduled to undergo supratentorial craniotomy were enrolled into this prospective, randomized, double-blind study. The patients were monitored for routine hemodynamic parameters, depth of anesthesia, and ICP...
July 31, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28761742/implementing-precision-cancer-medicine-in-the-public-health-services-of-norway-the-diagnostic-infrastructure-and-a-cost-estimate
#11
Anne Hansen Ree, Hege G Russnes, Daniel Heinrich, Svein Dueland, Kjetil Boye, Vigdis Nygaard, Laxmi Silwal-Pandit, Olga Østrup, Eivind Hovig, Vegard Nygaard, Einar A Rødland, Sigve Nakken, Janne T Øien, Christin Johansen, Inger R Bergheim, Veronica Skarpeteig, Menaka Sathermugathevan, Torill Sauer, Marius Lund-Iversen, Klaus Beiske, Salah Nasser, Lars Julsrud, Claudius H Reisse, Espen A Ruud, Vivi Ann Flørenes, Kirsten T Hagene, Eline Aas, Hilde Lurås, Siv Johnsen-Soriano, Gry A Geitvik, Ole Christian Lingjærde, Anne-Lise Børresen-Dale, Gunhild M Mælandsmo, Kjersti Flatmark
OBJECTIVE: Through the conduct of an individual-based intervention study, the main purpose of this project was to build and evaluate the required infrastructure that may enable routine practice of precision cancer medicine in the public health services of Norway, including modelling of costs. METHODS: An eligible patient had end-stage metastatic disease from a solid tumour. Metastatic tissue was analysed by DNA sequencing, using a 50-gene panel and a study-generated pipeline for analysis of sequence data, supplemented with fluorescence in situ hybridisation to cover relevant biomarkers...
2017: ESMO Open
https://www.readbyqxmd.com/read/28757884/the-fuzzy-world-of-precision-medicine-deliberations-of-a-precision-medicine-tumor-board
#12
Sarah A McGraw, Judy Garber, Pasi A Jänne, Neal Lindeman, Nelly Oliver, Lynette M Sholl, Eliezer M Van Allen, Nikhil Wagle, Levi A Garraway, Steven Joffe, Stacy W Gray
AIM: To understand how a cancer precision medicine tumor board (CPM-TB) made choices about return of results. MATERIALS & METHODS: Observed CPM-TB deliberations and completed in-depth interviews with committee members. RESULTS: Responding to complex evidence of ambiguous significance, deliberations of the CPM-TB were predicated on analytic validity and clinical utility. Members had concerns both about potential harms due to returning results based on weak evidence and about withholding potentially meaningful results...
January 2017: Personalized Medicine
https://www.readbyqxmd.com/read/28756056/healthcare-costs-related-to-treatment-of-hepatocellular-carcinoma-among-veterans-with-cirrhosis-in-the-united-states
#13
David E Kaplan, Michael K Chapko, Rajni Mehta, Feng Dai, Melissa Skanderson, Ayse Aytaman, Michelle Baytarian, Kathryn D'Addeo, Rena Fox, Kristel Hunt, Christine Pocha, Adriana Valderrama, Tamar H Taddei
BACKGROUND & AIMS: It is important to quantify medical costs associated with hepatocellular carcinoma (HCC), the incidence of which is rapidly increasing incidence in the United States, for development of rational healthcare policies related to liver cancer surveillance and treatment of chronic liver disease. We aimed to comprehensively quantify healthcare costs for HCC among patients with cirrhosis in an integrated health system and develop a model for predicting costs based on clinically relevant variables...
July 26, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28755703/through-the-glass-brightly-pathology-review-in-the-multidisciplinary-setting
#14
REVIEW
Margaret Brandwein-Weber
Hospital-centered academic surgical pathologists are essential members of multidisciplinary head and neck tumor boards. A working, multidisciplinary head and neck tumor board is composed of many dedicated professionals who contribute their individual pieces of patient data. This weekly congregation of head and neck specialists results in a special, concerted, and dynamic process of data integration into a holistic matrix view of the patients. Despite all the technological advances in communication, the fundamentals of human interactions still apply: there is no better substitute for a regular, working, multidisciplinary head and neck tumor board...
August 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28753807/diagnostic-needle-biopsies-in-renal-masses-patient-and-physician-perspectives
#15
Shay Golan, Paz Lotan, Shlomi Tapiero, Jack Baniel, Andrei Nadu, Ofer Yossepowitch
BACKGROUND: The utility of renal mass biopsies (RMB) in the diagnosis of kidney tumors remains debatable. OBJECTIVE: To assess patient and urologist preferences regarding the utilization of RMB. DESIGN, SETTING, AND PARTICIPANTS: Seventy-three patients diagnosed with renal tumors and 59 board-certified urologists were asked to participate in an interview-based study. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Using the standard gamble method we determined the minimal accepted accuracy at which RMB would be favored as part of the diagnostic process...
November 23, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28752518/the-color-of-cancer-margin-guidance-for-oral-cancer-resection-using-elastic-scattering-spectroscopy
#16
Gregory A Grillone, Zimmern Wang, Gintas P Krisciunas, Angela C Tsai, Vishnu R Kannabiran, Robert W Pistey, Qing Zhao, Eladio Rodriguez-Diaz, Ousama M A'Amar, Irving J Bigio
OBJECTIVES/HYPOTHESIS: To evaluate the usefulness of elastic scattering spectroscopy (ESS) as a diagnostic adjunct to frozen section analysis in patients with diagnosed squamous cell carcinoma of the oral cavity. STUDY DESIGN: Prospective analytic study. METHODS: Subjects for this single institution, institutional review board-approved study were recruited from among patients undergoing surgical resection for squamous cell cancer of the oral cavity...
July 28, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28751166/clinical-and-demographic-characteristics-among-patients-with-urothelial-carcinomas-of-the-upper-urinary-tract-and-bladder-in-taiwan
#17
Cheng-Huang Shen, Hung-Yi Chiou, Min-Che Tung, Chia-Chang Wu, Wei-Tang Kao, Yuan-Hung Wang, Guang-Dar Juang
BACKGROUND: Urothelial carcinoma (UC) is derived from the urothelium of the urinary tract, and includes cancers of the bladder, renal pelvis and ureter. The aim of this study was to investigate the clinical and demographic features among patients with bladder cancer and urothelial carcinoma of the upper urinary tract (UTUC) in Taiwan. METHODS: The present study recruited a total of 736 histopathologically confirmed UC cases, which consisted of 470 bladder cancer and 266 UTUC between September 1998 and December 2009...
July 24, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28742975/tumor-imaging-instruction-and-assessment-at-chiropractic-colleges-in-north-america-a-pilot-study-with-implications-for-national-board-of-chiropractic-examiners-content
#18
Kathleen L Linaker, Sarah A Arpin, Charles P Fischer, Michael Sackett, Lesley Georger
OBJECTIVE: This pilot study tested a survey instrument pertaining to the instruction and assessment of tumor imaging in chiropractic training programs. The secondary purpose was to gather data regarding credentials of lead instructors, textbook and resource use, and tumors taught and assessed. METHODS: An electronic survey was distributed to lead tumor imaging instructors at all chiropractic colleges in the United States and Canada. A focus group of tumor imaging instructors was conducted to clarify ambiguous data...
July 25, 2017: Journal of Chiropractic Education
https://www.readbyqxmd.com/read/28740920/pathologic-response-after-neoadjuvant-chemotherapy-predicts-locoregional-control-in-patients-with-triple-negative-breast-cancer
#19
Victor E Chen, Erin F Gillespie, Kaveh Zakeri, James D Murphy, Catheryn M Yashar, Sharon Lu, John P Einck
PURPOSE: Our goal was to determine the impact of pathologic response after neoadjuvant chemotherapy in triple negative breast cancer (TNBC) on the subsequent risk of locoregional recurrence (LRR) and disease-free survival (DFS) in the setting of adjuvant radiation therapy. METHODS AND MATERIALS: This was an institutional review board-approved retrospective chart review of patients with clinical stage I-III breast cancer treated with neoadjuvant chemotherapy, local surgery (breast conservation or mastectomy), and adjuvant radiation therapy between 1997 and 2015...
April 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740912/effect-of-variations-in-atelectasis-on-tumor-displacement-during-radiation-therapy-for-locally-advanced-lung-cancer
#20
Nathan Tennyson, Elisabeth Weiss, William Sleeman, Mihaela Rosu, Nuzhat Jan, Geoffrey D Hugo
PURPOSE: Atelectasis (AT), or collapsed lung, is frequently associated with central lung tumors. We investigated the variation of atelectasis volumes during radiation therapy and analyzed the effect of AT volume changes on the reproducibility of the primary tumor (PT) position. METHODS AND MATERIALS: Twelve patients with lung cancer who had AT and 10 patients without AT underwent repeated 4-dimensional fan beam computed tomography (CT) scans during radiation therapy per protocols that were approved by the institutional review board...
January 2017: Advances in Radiation Oncology
keyword
keyword
113416
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"