keyword
MENU ▼
Read by QxMD icon Read
search

Rapid deployment

keyword
https://www.readbyqxmd.com/read/29142513/sedation-for-routine-gastrointestinal-endoscopic-procedures-a-review-on-efficacy-safety-efficiency-cost-and-satisfaction
#1
REVIEW
Otto S Lin
Most gastrointestinal endoscopic procedures are now performed with sedation. Moderate sedation using benzodiazepines and opioids continue to be widely used, but propofol sedation is becoming more popular because its unique pharmacokinetic properties make endoscopy almost painless, with a very predictable and rapid recovery process. There is controversy as to whether propofol should be administered only by anesthesia professionals (monitored anesthesia care) or whether properly trained non-anesthesia personnel can use propofol safely via the modalities of nurse-administered propofol sedation, computer-assisted propofol sedation or nurse-administered continuous propofol sedation...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29141595/eeg-dynamical-correlates-of-focal-and-diffuse-causes-of-coma
#2
MohammadMehdi Kafashan, Shoko Ryu, Mitchell J Hargis, Osvaldo Laurido-Soto, Debra E Roberts, Akshay Thontakudi, Lawrence Eisenman, Terrance T Kummer, ShiNung Ching
BACKGROUND: Rapidly determining the causes of a depressed level of consciousness (DLOC) including coma is a common clinical challenge. Quantitative analysis of the electroencephalogram (EEG) has the potential to improve DLOC assessment by providing readily deployable, temporally detailed characterization of brain activity in such patients. While used commonly for seizure detection, EEG-based assessment of DLOC etiology is less well-established. As a first step towards etiological diagnosis, we sought to distinguish focal and diffuse causes of DLOC through assessment of temporal dynamics within EEG signals...
November 15, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29138903/next-generation-sequencing-to-identify-candidate-genes-and-develop-diagnostic-markers-for-a-novel-phytophthora-resistance-gene-rpshc18-in-soybean
#3
Chao Zhong, Suli Sun, Yinping Li, Canxing Duan, Zhendong Zhu
A novel Phytophthora sojae resistance gene RpsHC18 was identified and finely mapped on soybean chromosome 3. Two NBS-LRR candidate genes were identified and two diagnostic markers of RpsHC18 were developed. Phytophthora root rot caused by Phytophthora sojae is a destructive disease of soybean. The most effective disease-control strategy is to deploy resistant cultivars carrying Phytophthora-resistant Rps genes. The soybean cultivar Huachun 18 has a broad and distinct resistance spectrum to 12 P. sojae isolates...
November 14, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29138016/the-challenges-of-detecting-and-responding-to-a-lassa-fever-outbreak-in-an-ebola-affected-setting
#4
E L Hamblion, P Raftery, A Wendland, E Dweh, G S Williams, R N C George, L Soro, V Katawera, P Clement, A N Gasasira, E Musa, T K Nagbe
OBJECTIVES: Lassa fever(LF), a priority emerging pathogen likely to cause major epidemics, is endemic in much of West Africa and difficult to distinguish from other viral haemorrhagic fevers including Ebola virus disease(EVD). Definitive diagnosis requires laboratory confirmation not widely available in affected settings. We report the public health action to contain a LF outbreak and challenges encountered in an EVD-affected setting. METHODS: In February 2016 a rapid response team was deployed in Liberia in response to a cluster of LF cases...
November 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29132703/rapid-deployment-aortic-valve-replacement-excellent-results-and-increased-effective-orifice-areas
#5
Parwis B Rahmanian, Süreyya Kaya, Kaveh Eghbalzadeh, Hruy Menghesha, Navid Madershahian, Thorsten Wahlers
BACKGROUND: The aim of this study was to evaluate the effects of rapid deployment aortic valve replacement (RDAVR) on surgical outcome and hemodynamics compared with standard aortic valve replacement (AVR). METHODS: One hundred sixty-three RDAVR patients (isolated, n = 67; combined with coronary artery bypass graft surgery [CABG], n = 96) were compared with a propensity matched control group (n = 163). Primary endpoints included association between valve type and procedure times, prosthesis size, transvalvular gradient, and indexed effective orifice area...
November 10, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29132318/bugmat-and-findneighbour-command-line-and-server-applications-for-investigating-bacterial-relatedness
#6
Oriol Mazariegos-Canellas, Trien Do, Tim Peto, David W Eyre, Anthony Underwood, Derrick Crook, David H Wyllie
BACKGROUND: Large scale bacterial sequencing has made the determination of genetic relationships within large sequence collections of bacterial genomes derived from the same microbial species an increasingly common task. Solutions to the problem have application to public health (for example, in the detection of possible disease transmission), and as part of divide-and-conquer strategies selecting groups of similar isolates for computationally intensive methods of phylogenetic inference using (for example) maximal likelihood methods...
November 13, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29131825/a-model-based-clustering-method-to-detect-infectious-disease-transmission-outbreaks-from-sequence-variation
#7
Rosemary M McCloskey, Art F Y Poon
Clustering infections by genetic similarity is a popular technique for identifying potential outbreaks of infectious disease, in part because sequences are now routinely collected for clinical management of many infections. A diverse number of nonparametric clustering methods have been developed for this purpose. These methods are generally intuitive, rapid to compute, and readily scale with large data sets. However, we have found that nonparametric clustering methods can be biased towards identifying clusters of diagnosis-where individuals are sampled sooner post-infection-rather than the clusters of rapid transmission that are meant to be potential foci for public health efforts...
November 13, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29130601/scaling-up-hiv-viral-load-lessons-from-the-large-scale-implementation-of-hiv-early-infant-diagnosis-and-cd4-testing
#8
Trevor Peter, Clement Zeh, Zachary Katz, Ali Elbireer, Bereket Alemayehu, Lara Vojnov, Alex Costa, Naoko Doi, Ilesh Jani
INTRODUCTION: The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong WHO guidance recommending routine testing to identify treatment failure. However, test implementation faces challenges related to the developing health systems in many low-resource countries. The purpose of this commentary is to review the challenges and solutions from the large-scale implementation of other diagnostic tests, namely nucleic-acid based early infant HIV diagnosis (EID) and CD4 testing, and identify key lessons to inform the scale-up of VL...
November 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29128981/what-to-eat-in-a-warming-world-do-increased-temperatures-necessitate-hazardous-duty-pay
#9
L Embere Hall, Anna D Chalfoun
Contemporary climate change affects nearly all biomes, causing shifts in animal distributions and resource availability. Changes in resource selection may allow individuals to offset climatic stress, thereby providing a mechanism for persistence amidst warming conditions. Whereas the role of predation risk in food choice has been studied broadly, the extent to which individuals respond to thermoregulatory risk by changing resource preferences is unclear. We addressed whether individuals compensated for temperature-related reductions in foraging time by altering forage preferences, using the American pika (Ochotona princeps) as a model species...
November 11, 2017: Oecologia
https://www.readbyqxmd.com/read/29128034/use-of-extracorporeal-membrane-oxygenation-and-surgical-embolectomy-for-massive-pulmonary-embolism-in-the-emergency-department
#10
De Ante Russ, Nicole Payne, Mark Bonnell, Viviane Kazan
BACKGROUND: Massive pulmonary embolism (PE) carries significant morbidity and mortality with current standard of care modalities. CASE REPORT: We present the case of a 63-year-old male status post abdominal surgery 2 weeks before presenting to the emergency department with a massive pulmonary embolism and subsequent acute cardiopulmonary failure. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Here we describe a case of extracorporeal membrane oxygenation (ECMO) deployed in the emergency department as a bridge to embolectomy to successfully treat massive pulmonary embolism...
November 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29124905/rapid-and-simple-detection-of-foot-and-mouth-disease-virus-evaluation-of-a-cartridge-based-molecular-detection-system-for-use-in-basic-laboratories
#11
K V Goller, V Dill, M Madi, P Martin, Y Van der Stede, V Vandenberge, B Haas, S Van Borm, F Koenen, C J Kasanga, N Ndusilo, M Beer, L Liu, V Mioulet, B Armson, D P King, V L Fowler
Highly contagious transboundary animal diseases such as foot-and-mouth disease (FMD) are major threats to the productivity of farm animals. To limit the impact of outbreaks and to take efficient steps towards a timely control and eradication of the disease, rapid and reliable diagnostic systems are of utmost importance. Confirmatory diagnostic assays are typically performed by experienced operators in specialized laboratories, and access to this capability is often limited in the developing countries with the highest disease burden...
November 9, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29121559/a-screen-printed-paper-microbial-fuel-cell-biosensor-for-detection-of-toxic-compounds-in-water
#12
Jon Chouler, Álvaro Cruz-Izquierdo, Saravanan Rengaraj, Janet L Scott, Mirella Di Lorenzo
Access to safe drinking water is a human right, crucial to combat inequalities, reduce poverty and allow sustainable development. In many areas of the world, however, this right is not guaranteed, in part because of the lack of easily deployable diagnostic tools. Low-cost and simple methods to test water supplies onsite can protect vulnerable communities from the impact of contaminants in drinking water. Ideally such devices would also be easy to dispose of so as to leave no trace, or have a detrimental effect on the environment...
November 6, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29119993/a-study-of-the-reactivity-of-s-vi-f-containing-warheads-with-nucleophilic-amino-acid-side-chains-under-physiological-conditions
#13
H Mukherjee, J Debreczeni, J Breed, S Tentarelli, B Aquila, J E Dowling, A Whitty, N P Grimster
Sulfonyl fluorides (SFs) have recently emerged as a promising warhead for the targeted covalent modification of proteins. Despite numerous examples of the successful deployment of SFs as covalent probe compounds, a detailed exploration of the factors influencing the stability and reactivity of SFs has not yet appeared. In this work we present an extensive study on the influence of steric and electronic factors on the reactivity and stability of the SF and related S(VI)-F groups. While SFs react rapidly with N-acetylcysteine, the resulting adducts were found to be unstable, rendering SFs inappropriate for the durable covalent inhibition of cysteine residues...
November 9, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29118062/wearables-for-promoting-physical-activity
#14
REVIEW
Scott J Strath, Taylor W Rowley
BACKGROUND: The rapid expansion and popularity of consumer-wearable physical activity monitors (WPAMs) has enabled the integration of technology into physical activity (PA) intervention, deployment, and evaluation. This brief review reports on the accuracy of consumer-WPAMs, considers the intervention effects of using consumer-WPAMs, and offers future considerations as the proliferation of this area of product development and consumer use continues to escalate. CONTENT: The studies reviewed document the utility for consumer-WPAMs to objectively assess PA, with output metrics similar to research-grade activity monitors...
November 8, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29117637/secondary-ion-mass-spectrometry-imaging-and-multivariate-data-analysis-reveal-co-aggregation-patterns-of-populus-trichocarpa-leaf-surface-compounds-on-a-micrometer-scale
#15
Purva Kulkarni, Mina Dost, Özgül Demir Bulut, Alexander Welle, Sebastian Böcker, Wilhelm Boland, Aleš Svatoš
Spatially resolved analysis of a multitude of compound classes has become feasible with the rapid advancement in mass spectrometry imaging strategies. In this study, we present a protocol that combines high lateral resolution TOF-SIMS imaging with a multivariate data analysis (MVA) approach to probe the complex leaf surface chemistry of Populus trichocarpa. Here, epicuticular waxes (EWs) found on the adaxial leaf surface of Populus trichocarpa were blotted on silicon wafers and imaged using time-of-flight secondary ion mass spectrometry (TOF-SIMS) at 10 μm and 1 μm lateral resolution...
November 8, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29104340/rapid-on-site-radionuclide-screening-of-aqueous-waste-streams-using-dip-stick-technologies-and-liquid-scintillation-counting
#16
Phillip E Warwick, Ian W Croudace
This paper describes an early-stage evaluation of a purpose-designed extraction/detection system that can be deployed by non-specialists either on-site or as part of a mobile laboratory. The system comprises three main components; (1) an optimised compact extraction system for recovery of radionuclides from the waste form; (2) an extraction test strip designed to recover the radionuclides from the waste digest; (3) a scintillation-based detection system capable of quantification of alpha, low energy beta and high energy beta emitting radionuclides...
2017: Journal of Radioanalytical and Nuclear Chemistry
https://www.readbyqxmd.com/read/29103865/human-endothelial-cell-collection-from-the-middle-cerebral-artery-in-acute-ischemic-stroke
#17
Sunil A Sheth, Abhishek Verma, Konark Malhotra, Xiannan Tang, Satoshi Tateshima, Reza Jahan, Jason D Hinman
BACKGROUND: Endovascular treatment for large-vessel acute ischemic stroke (AIS) has rapidly emerged. However, the understanding of the complex biology involving endothelial cells (ECs) remains scarce. METHODS: Using stent retrievers during endovascular thrombectomy (ET) in patients with AIS, ECs were segregated, centrifuged in a dissociation buffer, and suspended in endothelial specific antibody solution. Subsequently, fluorescence-activated cell sorting (FACS) and microscopic analyses were performed...
November 2, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29096576/endovascular-treatment-of-aortic-arch-lesions-using-scalloped-endografts
#18
Leopoldo Fernández-Alonso, Sebastián Fernández Alonso, Esther Martínez Aguilar, Estéfana Santamarta Fariña, Jordi Alegret Solé, Marina López San Martín, Margarita Atienza Pascual, Leopoldo Fernández-Domper, Roberto Centeno Vallepuga
OBJECTIVE: To present our early and midterm results using thoracic endovascular aortic repair (TEVAR) with a custom-made proximal scalloped stent graft to accommodate left common carotid artery (LCCA) and innominate artery (IA) in treating aortic lesions involving the arch. MATERIALS AND METHODS: Between February 2014 and April 2017, select patients presenting with aortic arch lesions and short proximal landing zone were treated by proximal scalloped Relay Plus stent grafts...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29081242/assessing-the-special-need-for-protection-of-vulnerable-refugees-testing-the-applicability-of-a-screening-method-rhs-15-to-detect-traumatic-disorders-in-a-refugee-sample-in-germany
#19
Markus Stingl, Michael Knipper, Björge Hetzger, Jessica Richards, Bülent Yazgan, Bernd Gallhofer, Bernd Hanewald
OBJECTIVES: Although EU member states are obligated to take special account of the situation of particularly vulnerable refugees, appropriate and specific measures to detect affected asylum seekers are not yet available. This study tries to pave the way for the implementation of an adequate instrument which at the same time assesses these needs of suffering people whilst responding to the need for mental health assessments specifically designed for refugees. This was done by testing the implementation of a screening method (Refugee Health Screener RHS-15) for trauma related mental health problems in refugees...
October 29, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29079947/the-cost-and-cost-utility-of-three-public-health-hiv-case-finding-strategies-evidence-from-rhode-island-2012-2014
#20
Xinqi C Li, Lillian Kusi, Theodore Marak, Thomas Bertrand, Philip A Chan, Omar Galárraga
To evaluate three testing strategies to identify new HIV diagnoses in Rhode Island (RI). RI deployed three testing strategies, by using rapid HIV tests at clinical settings, community-based organization (CBO) settings, and the Partner Notification Services (PNS) program from 2012 to 2014. We reviewed the rapid HIV test results and confirmatory test results to identify new diagnoses, and conducted a cost-utility analysis. The average cost per new diagnosis was $33,015 at CBO settings, $5446 at clinical settings, and $33,818 at the PNS program...
October 27, 2017: AIDS and Behavior
keyword
keyword
113399
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"