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https://www.readbyqxmd.com/read/28222727/developing-global-maps-of-insecticide-resistance-risk-to-improve-vector-control
#1
Michael Coleman, Janet Hemingway, Katherine Ann Gleave, Antoinette Wiebe, Peter W Gething, Catherine L Moyes
BACKGROUND: Significant reductions in malaria transmission have been achieved over the last 15 years with elimination occurring in a small number of countries, however, increasing drug and insecticide resistance threatens these gains. Insecticide resistance has decreased the observed mortality to the most commonly used insecticide class, the pyrethroids, and the number of alternative classes approved for use in public health is limited. Disease prevention and elimination relies on operational control of Anopheles malaria vectors, which requires the deployment of effective insecticides...
February 21, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28221970/genomic-tools-for-customized-recovery-and-detection-of-foodborne-shiga-toxigenic-escherichia-coli
#2
Michael Knowles, Sara Stinson, Dominic Lambert, Catherine Carrillo, Adam Koziol, Martine Gauthier, Burton Blais
Genomic antimicrobial resistance (AMR) prediction tools have the potential to support foodborne illness outbreak investigations through their application in the analysis of bacterial genomes from causative strains. The AMR marker profile of a strain of interest, initially identified in outbreak-associated clinical samples, may serve as the basis for customization of selective enrichment media, facilitating its recovery from samples in a food safety investigation. Different possibilities for AMR analyses include the use of comprehensive AMR gene databases such as the Comprehensive Antibiotic Resistance Database, which can be mined with in-house bioinformatics alignment tools (e...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28219552/unusual-gastrointestinal-bleeding-after-sutureless-aortic-valve-replacement-a-word-of-caution
#3
Jules Iquille, Joseph Nader, Eric Colpart, Thierry Caus
We report the clinical case of a male patient who presented, after an aortic valve replacement with a rapid deployment bioprosthesis, a Heyde-like syndrome, secondary to a moderate aortic paravalvular leakage. All the digestive and hematologic investigations confirmed the diagnosis. A redo surgery to fill the paravalvular gap was accomplished and the postoperative course was uneventful, with a normalization of the biological parameters. To our knowledge, this is the first described case of such a complication with the new generation of sutureless bioprosthesis...
March 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28214576/amplified-induced-neural-oscillatory-activity-predicts-musicians-benefits-in-categorical-speech-perception
#4
Gavin M Bidelman
Event-related brain potentials (ERPs) reveal musical experience refines neural encoding and confers stronger categorical perception (CP) and neural organization for speech sounds. In addition to evoked brain activity, the human EEG can be decomposed into induced (non-phase-locked) response whose various frequency bands reflect different mechanisms of perceptual-cognitive processing. Here, we aimed to clarify which spectral properties of these neural oscillations are most prone to music-related neuroplasticity and which are linked to behavioral benefits in the categorization of speech...
February 15, 2017: Neuroscience
https://www.readbyqxmd.com/read/28213666/patterns-of-abnormal-gastric-pacemaking-after-sleeve-gastrectomy-defined-by-laparoscopic-high-resolution-electrical-mapping
#5
Rachel Berry, Leo K Cheng, Peng Du, Niranchan Paskaranandavadivel, Timothy R Angeli, Terence Mayne, Grant Beban, Gregory O'Grady
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is increasingly being applied to treat obesity. LSG includes excision of the normal gastric pacemaker, which could induce electrical dysrhythmias impacting on post-operative symptoms and recovery, but these implications have not been adequately investigated. This study aimed to define the effects of LSG on gastric slow-wave pacemaking using laparoscopic high-resolution (HR) electrical mapping. METHODS: Laparoscopic HR mapping was performed before and after LSG using flexible printed circuit arrays (64-96 electrodes; 8-12 cm(2); n = 8 patients) deployed through a 12 mm trocar and positioned on the gastric serosa...
February 17, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28213216/graphene-quantum-dots-decorated-with-maleimide-and-zinc-tetramaleimido-phthalocyanine-application-in-the-design-of-off-on-fluorescence-sensors-for-biothiols
#6
Ojodomo J Achadu, Tebello Nyokong
The fabrication of maleimide-derivatized graphene quantum dots (M-GQDs) and zinc phthalocyanine (2) as novel sensor probes for the selective detection of biothiols (cysteine, homocysteine or glutathione) through the rapid and specific Michael addition reaction between biothiols and the maleimide-derivatized probes is presented in this study. GQDs directly functionalized with maleimide units (M-GQDs) were synthesized and deployed for biothiols recognition following the principle of Michael addition. M-GQDs probe was found to be highly sensitive and selective towards biothiols detection in the nanomolar range in aqueous solution and at physiological pH (7...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28208735/probabilistic-neighborhood-based-data-collection-algorithms-for-3d-underwater-acoustic-sensor-networks
#7
Guangjie Han, Shanshan Li, Chunsheng Zhu, Jinfang Jiang, Wenbo Zhang
Marine environmental monitoring provides crucial information and support for the exploitation, utilization, and protection of marine resources. With the rapid development of information technology, the development of three-dimensional underwater acoustic sensor networks (3D UASNs) provides a novel strategy to acquire marine environment information conveniently, efficiently and accurately. However, the specific propagation effects of acoustic communication channel lead to decreased successful information delivery probability with increased distance...
February 8, 2017: Sensors
https://www.readbyqxmd.com/read/28199446/translational-control-in-plant-antiviral-immunity
#8
João Paulo B Machado, Iara P Calil, Anésia A Santos, Elizabeth P B Fontes
Due to the limited coding capacity of viral genomes, plant viruses depend extensively on the host cell machinery to support the viral life cycle and, thereby, interact with a large number of host proteins during infection. Within this context, as plant viruses do not harbor translation-required components, they have developed several strategies to subvert the host protein synthesis machinery to produce rapidly and efficiently the viral proteins. As a countermeasure against infection, plants have evolved defense mechanisms that impair viral infections...
February 13, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28198045/composite-graft-using-an-edwards-intuity-elite-rapid-deployment-bioprosthesis-for-aortic-root-replacement
#9
Marco Gennari, Marco Agrifoglio, Gianluca Polvani
We describe a technique using an Edwards Intuity Elite rapid deployment bioprosthesis to construct a composite graft for an aortic root replacement.
February 15, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28197620/measuring-practicing-clinicians-information-literacy-an-exploratory-analysis-in-the-context-of-panel-management
#10
Brian E Dixon, Katherine Barboza, Ashley E Jensen, Katelyn J Bennett, Scott E Sherman, Mark D Schwartz
BACKGROUND: As healthcare moves towards technology-driven population health management, clinicians must adopt complex digital platforms to access health information and document care. OBJECTIVES: This study explored information literacy, a set of skills required to effectively navigate population health information systems, among primary care providers in one Veterans' Affairs (VA) medical center. METHODS: Information literacy was assessed during an 8-month randomized trial that tested a population health (panel) management intervention...
February 15, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28194831/comparing-two-processing-pipelines-to-measure-subcortical-and-cortical-volumes-in-patients-with-and-without-mild-traumatic-brain-injury
#11
Matthew W Reid, Nathan P Hannemann, Gerald E York, John L Ritter, Jonathan A Kini, Jeffrey D Lewis, Paul M Sherman, Carmen S Velez, Ann Marie Drennon, Jacob D Bolzenius, David F Tate
PURPOSE: To compare volumetric results from NeuroQuant® and FreeSurfer in a service member setting. Since the advent of medical imaging, quantification of brain anatomy has been a major research and clinical effort. Rapid advancement of methods to automate quantification and to deploy this information into clinical practice has surfaced in recent years. NeuroQuant® is one such tool that has recently been used in clinical settings. Accurate volumetric data are useful in many clinical indications; therefore, it is important to assess the intermethod reliability and concurrent validity of similar volume quantifying tools...
February 14, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28186400/formulation-of-aminosilica-adsorbents-into-3d-printed-monoliths-and-evaluation-of-their-co2-capture-performance
#12
Harshul Thakkar, Stephen Eastman, Ahmed Al-Mamoori, Amit Hajari, Ali A Rownaghi, Fateme Rezaei
Amine-based materials have represented themselves as a promising class of CO2 adsorbents; however, their large-scale implementation requires their formulation into suitable structures. In this study, we report formulation of aminosilica adsorbents into monolithic structures through a three-dimensional (3D) printing technique. In particular, 3D-printed monoliths were fabricated using presynthesized silica-supported tetraethylenepentamine (TEPA) and poly(ethylenimine) (PEI) adsorbents using three different approaches...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28182479/the-first-letter-position-effect-in-visual-word-recognition-the-role-of-spatial-attention
#13
Andrew J Aschenbrenner, David A Balota, Alexandra J Weigand, Michele Scaltritti, Derek Besner
A prominent question in visual word recognition is whether letters within a word are processed in parallel or in a left to right sequence. Although most contemporary models posit parallel processing, this notion seems at odds with well-established serial position effects in word identification that indicate preferential processing for the initial letter. The present study reports 4 experiments designed to further probe the locus of the first position processing advantage. The paradigm involved masked target words presented for short durations and required participants to subsequently select from 2 alternatives, 1 which was identical to the target and 1 that differed by a single letter...
February 9, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28181489/chip-based-quantum-key-distribution
#14
P Sibson, C Erven, M Godfrey, S Miki, T Yamashita, M Fujiwara, M Sasaki, H Terai, M G Tanner, C M Natarajan, R H Hadfield, J L O'Brien, M G Thompson
Improvement in secure transmission of information is an urgent need for governments, corporations and individuals. Quantum key distribution (QKD) promises security based on the laws of physics and has rapidly grown from proof-of-concept to robust demonstrations and deployment of commercial systems. Despite these advances, QKD has not been widely adopted, and large-scale deployment will likely require chip-based devices for improved performance, miniaturization and enhanced functionality. Here we report low error rate, GHz clocked QKD operation of an indium phosphide transmitter chip and a silicon oxynitride receiver chip-monolithically integrated devices using components and manufacturing processes from the telecommunications industry...
February 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28176766/a-fast-and-accurate-method-for-detection-of-ibd-shared-haplotypes-in-genome-wide-snp-data
#15
Douglas W Bjelland, Uday Lingala, Piyush S Patel, Matt Jones, Matthew C Keller
Identical by descent (IBD) segments are used to understand a number of fundamental issues in genetics. IBD segments are typically detected using long stretches of identical alleles between haplotypes in phased, whole-genome SNP data. Phase or SNP call errors in genomic data can degrade accuracy of IBD detection and lead to false-positive/negative calls and to under/overextension of true IBD segments. Furthermore, the number of comparisons increases quadratically with sample size, requiring high computational efficiency...
February 8, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28166743/molecular-point-of-care-testing-for-respiratory-viruses-versus-routine-clinical-care-in-adults-with-acute-respiratory-illness-presenting-to-secondary-care-a-pragmatic-randomised-controlled-trial-protocol-respoc
#16
Nathan J Brendish, Ahalya K Malachira, Tristan W Clark
BACKGROUND: Respiratory viruses are associated with a huge socio-economic burden and are responsible for a large proportion of acute respiratory illness in hospitalised adults. Laboratory PCR is accurate but takes at least 24 h to generate a result to clinicians and antigen-based point-of-care tests (POCT) lack sensitivity. Rapid molecular platforms, such as the FilmArray Respiratory Panel, have equivalent diagnostic accuracy to laboratory PCR and can generate a result in 1 h making them deployable as POCT...
February 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28163882/bioinspired-morphing-wings-for-extended-flight-envelope-and-roll-control-of-small-drones
#17
M Di Luca, S Mintchev, G Heitz, F Noca, D Floreano
Small-winged drones can face highly varied aerodynamic requirements, such as high manoeuvrability for flight among obstacles and high wind resistance for constant ground speed against strong headwinds that cannot all be optimally addressed by a single aerodynamic profile. Several bird species solve this problem by changing the shape of their wings to adapt to the different aerodynamic requirements. Here, we describe a novel morphing wing design composed of artificial feathers that can rapidly modify its geometry to fulfil different aerodynamic requirements...
February 6, 2017: Interface Focus
https://www.readbyqxmd.com/read/28161300/development-and-delivery-of-a-pharmacist-training-program-to-increase-naloxone-access-in-kentucky
#18
Emma Palmer, Steve Hart, Patricia R Freeman
OBJECTIVE: To describe the development and delivery of a comprehensive training program for Kentucky pharmacists to enable dispensation of naloxone per protocol. PRACTICE DESCRIPTION: In May 2015, the Kentucky Board of Pharmacy (KBP) promulgated regulations outlining the requirements for pharmacists to initiate the dispensing of naloxone under a physician-approved protocol. The Advancing Pharmacy Practice in Kentucky Coalition, a partnership between Kentucky's Colleges of Pharmacy, KBP, and state and local pharmacists associations, developed and offered educational programming to fulfill this regulation...
February 1, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28159916/impact-of-deploying-multiple-point-of-care-tests-with-a-sample-first-approach-on-a-sexual-health-clinical-care-pathway-a-service-evaluation
#19
Emma M Harding-Esch, Achyuta V Nori, Aseel Hegazi, Marcus J Pond, Olanike Okolo, Anthony Nardone, Catherine M Lowndes, Phillip Hay, S Tariq Sadiq
OBJECTIVES: To assess clinical service value of STI point-of-care test (POCT) use in a 'sample first' clinical pathway (patients providing samples on arrival at clinic, before clinician consultation). Specific outcomes were: patient acceptability; whether a rapid nucleic acid amplification test (NAAT) for Chlamydia trachomatis/Neisseria gonorrhoeae (CT/NG) could be used as a POCT in practice; feasibility of non-NAAT POCT implementation for Trichomonas vaginalis (TV) and bacterial vaginosis (BV); impact on patient diagnosis and treatment...
February 3, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28152972/using-a-collaborative-approach-for-rapid-deployment-of-advance-care-planning-in-the-outpatient-oncology-setting
#20
Jeffrey B Smerage, Jamie Lindsay, Laura Petersen, Keith Mark Swetz, Arif Kamal
: 255 Background: The Michigan Oncology Quality Consortium (MOQC) is a quality collaborative supported by Blue Cross Blue Shield of Michigan with the goal of improving cancer care in Michigan by using data gathered as part of the national Quality Oncology Practice Initiative (QOPI) program. In spring 2014, MOQC launched a statewide collaborative focused on advance care planning (ACP) with the following aim: to provide training and resources on how to engage patients in a discussion of goals, preferences, and priorities for care...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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