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vestibule schwannoma

Avi Shupak, Yehuda Holdstein, Margalit Kaminer, Itzhak Braverman
Intralabyrinthine schwannomas (ILSs) are uncommon benign tumors that originate in the Schwann cell sheath of the intralabyrinthine distal branches of the vestibulocochlear nerve. They have no initial involvement in the internal auditory canal, although that might develop later. These lesions can arise inside the cochlea, originate in the vestibule or, in rare cases, develop in the semicircular canals. From these sites, spread might take place via the anatomic connections between the perilymphatic spaces in the scala vestibuli and the anterior vestibule...
December 2016: Ear, Nose, & Throat Journal
Brian S Chen, Daniel S Roberts, Gregory P Lekovic
Background Rates of hearing preservation following surgery via middle fossa craniotomy in patients harboring tumors with unfavorable characteristics are significantly lower than for those patients with "favorable" tumors. Objectives We will present two cases both with unfavorable conditions, which underwent endoscopic-assisted middle fossa craniotomy (MFC) resection of intracanalicular vestibular schwannomas with preserved postoperative hearing. Methods Chart reviews were conducted on both patients. Their presentation, intraoperative details, and techniques, pre- and postoperative audiograms, and facial nerve outcomes are presented...
March 2016: Journal of Neurological Surgery Reports
Syed F Ahsan, Dennis Bojrab, Robert Standring
Objectives To describe a unique case report of a patient who had partial hearing preservation after translabyrinthine (TL) removal of a vestibular schwannoma (VS). Study Design Case report. Methods The patient's chart was reviewed for hearing levels before and after surgery. Preoperative magnetic resonance imaging (MRI) was compared with postoperative MRI for determination of completeness of tumor removal. The literature on hearing preservation after TL resection is reviewed. Results A 42-year-old woman underwent a TL removal of a VS...
November 2015: Journal of Neurological Surgery Reports
Martin Nue Møller, Søren Hansen, Per Caye-Thomasen
INTRODUCTION: Dizziness is a common symptom in patients with vestibulo-cochlear schwannoma (VS), and several recent studies have identified this symptom as the single most important concerning the quality of life. Clinical and histological observations regarding hearing loss have suggested that this may be caused by both cochlear and retrocochlear mechanisms. Multiple mechanisms may also be at play in the case of dizziness, which may broaden perspectives of therapeutic approach. This study presents a systematic and detailed assessment of vestibular histopathology in temporal bones from patients with VS...
September 2015: Otology & Neurotology
Ranjan Agrawal, Ashok Chauhan, Parbodh Kumar
AIM: The present study was undertaken to study the spectrum and pattern of various oral cavity lesions in a tertiary care hospital in Rohilkhand region of Uttar Pradesh, India. BACKGROUND: Oral cavity is one of the most common sites for tumour and tumour like lesions especially in males. It has been observed that benign lesions are more common than malignant ones. MATERIALS AND METHODS: A retrospective study was carried out in a tertiary care hospital during the period of two years from June 2012 to May 2014...
June 2015: Journal of Clinical and Diagnostic Research: JCDR
Andrea P Sponghini, Francesca Platini, David Rondonotti, Riccardo Soffietti
PURPOSE: Neurofibromatosis type 2 (NF2) is a dominantly inherited genetic condition that clinically manifests through the appearance of multiple meningiomas, ependymomas and bilateral vestibular schwannomas (acoustic neuromas) which lead to progressive hearing loss. Neovascularization is necessary for tumor growth and is driven by tumor-produced angiogenic factors such as vascular endothelial growth factor (VEGF). Bevacizumab is a humanized monoclonal antibody that neutralizes the activity of VEGF...
November 14, 2015: Tumori
Aline Gomes Bittencourt, Ricardo Dourado Alves, Liliane Satomi Ikari, Patrick Rademaker Burke, Eloisa Maria Santiago Gebrim, Ricardo Ferreira Bento
Introduction Schwannomas of the eighth cranial nerve are benign tumors that usually occur in the internal auditory canal or the cerebellopontine angle cistern. Rarely, these tumors may originate from the neural elements within the vestibule, cochlea, or semicircular canals and are called intralabyrinthine schwannomas. Intracochlear schwannomas (ICSs) represent a small percentage of these tumors, and their diagnosis is based on high-resolution magnetic resonance imaging (MRI). Objectives To report the clinical and radiologic features and audiometric testing results of an ICS in a 48-year-old man after a 22-month follow-up period...
July 2014: International Archives of Otorhinolaryngology
Justin R Mascitelli, Ian T McNeill, J Mocco, Alejandro Berenstein, Joseph DeMattia, Johanna T Fifi
Distal anterior inferior cerebellar artery (AICA) pseudoaneurysms are very rare lesions. Although cases have been previously reported, only a few have been reported as a result of vestibular schwannoma (VS) radiation, none have been reported as a result of VS resection, and only one has been reported as treated with parent vessel occlusion (PVO) with n-butyl cyanoacrylate (nBCA). We report a case of a 65-year-old man with a history of right-sided VS surgery and radiation who presented years later with a ruptured pseudoaneurysm of the distal right AICA and was treated with endovascular PVO using nBCA...
May 6, 2015: BMJ Case Reports
Hans Thomeer, Damien Bonnard, Valérie Franco-Vidal, Florence Porez, Patricia Darrouzet, Dominique Liguoro, Vincent Darrouzet
OBJECTIVES: To evaluate short- and mid-term level of imbalance after vestibular schwannoma (VS) microsurgery by the transpetrosal approach, to search for factors predictive of vestibular compensation, and to determine which patient categories need a postoperative vestibular rehabilitation program. STUDY DESIGN: Prospective cohort study at a tertiary referral center. METHODS: Between 2010 and 2011, patients aged 18 to 75 operated on for VS by transpetrosal approaches were included...
June 2015: Otology & Neurotology
Huizeng You, Xiaoying Li, Wuqing Wang
Vestibular schwannoma is a rare tumor, which is easily misdiagnosed. The authors presented a case of vestibular schwannoma in a 36-year-old woman. The clinical manifestations were recurrent vertigo, hearing loss of the left ear, and tinnitus. The pure tone audiometry threshold of the left ear was 45dBHL with air conduction, and 33 dBHL with bone conduction. A CT scan of the temporal bone region didn't show any abnormal finding. A MRI scan of the head showed nodule abnormal signal in the internal of left vestibular and the narrow of perilymphaticum gap in T2W1 + T2Flair...
November 2014: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Leopoldo Casentini, Umberto Fornezza, Zeno Perini, Egle Perissinotto, Federico Colombo
OBJECT: Microsurgery is not the only option for larger vestibular schwannomas (VSs); recent reviews have confirmed the feasibility and efficacy of radiosurgery for larger VSs. This study illustrates the outcomes of a series of large VSs after multisession stereotactic radiosurgery (SRS). METHODS: A series of 33 VSs larger than 8 cm(3) (range 8-24 cm(3), mean 11 cm(3), median 9.4 cm(3)) were treated using the CyberKnife from 2003 to 2011 with the multisession SRS technique in 2-5 fractions (14-19...
April 2015: Journal of Neurosurgery
Tamara Mijovic, Jerôme Carriot, Anthony Zeitouni, Kathleen E Cullen
OBJECTIVES: (1) To determine if head movements in patients with vestibular deficiency differ from those in normal subjects during daily life activities. (2) To assess if these differences can be correlated with patients' perception of dizziness-induced handicap. STUDY DESIGN: Prospective matched-pairs study SETTING: Tertiary referral center PATIENTS: Thirty-one vestibular schwannoma patients with documented postoperative unilateral vestibular loss and their age-, gender-, and physical activity level-matched controls with symmetric vestibulo-ocular reflexes...
December 2014: Otology & Neurotology
Laurence Ribeyre, Julien Frère, Gérome Gauchard, Alexis Lion, Philippe Perrin, Elisabeth Spitz, Cécile Parietti-Winkler
OBJECTIVE: The influence of tumor size on postural control of patients with vestibular schwannoma (VS) remains to be determined. This study aimed to compare the postural performances of VS patients, according to the size of the tumor, with healthy subjects. METHODS: The six conditions (C1-C6) of the sensory organization test (SOT) were carried out in 87 patients, split into four groups according to the Koos classification (stage I-IV), and in 72 aged-matched controls to evaluate postural control...
April 2015: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Xavier Dubernard, Thomas Somers, Konstantinos Veros, Christophe Vincent, Valérie Franco-Vidal, Olivier Deguine, Philippe Bordure, Thomas Linder, Emmanuel Lescanne, Denis Ayache, Michel Mondain, Sébastien Schmerber, Myriam Dahmani-Causse, Eric Truy, Vincent Darrouzet
OBJECTIVE: To describe the presentation of intralabyrinthine schwannomas (ILSs). STUDY DESIGN AND SETTING: Retrospective multicenter study involving 12 European skull base surgery tertiary referral centers. PATIENTS: One hundred ten patients with the diagnosis of ILS, either labyrinth confined or extending into the internal auditory meatus for less than 50% of their volume. MAIN OUTCOME MEASURES: Data collected were age, sex, nature and timing of presenting symptoms, hearing (according to the AAO-HNS grading system), results of vestibular tests (caloric tests and cervical vestibular-evoked myogenic potentials [c-VEMPs]), and tumor localization...
October 2014: Otology & Neurotology
Ismail Fadzilah, Husain Salina, Baharudin Khairuzzana, Omar Rahmat, S H Primuharsa Putra
Schwannomas of the nasal cavity and paranasal sinuses are quite rare, especially in the nasal vestibule. We report the case of a 61-year-old woman who presented with a 2-month history of progressively worsening right-sided epistaxis and nasal blockage. Rigid nasoendoscopy showed a mobile, smooth, globular mass occupying the right nasal vestibule. The mass arose from the lateral nasal wall and impinged on the anterior part of the middle turbinate posteriorly. Computed tomography of the paranasal sinuses showed a 3...
June 2014: Ear, Nose, & Throat Journal
Mark J Stavas, Matthew L Carlson, Albert Attia, Gary P Jacobson, Alejandro Rivas, Manuel Morales-Paliza, George B Wanna
OBJECTIVE: To date, the majority of the vestibular schwannoma (VS) literature has focused on tumor control rates, facial nerve function and hearing preservation. Other factors that have been shown to significantly affect quality-of-life (QOL), such as dizziness, remain understudied. The primary objective of the current study is to investigate the association between radiation dose to the vestibule and post-treatment changes in vestibular function and patient reported dizziness handicap...
September 2014: American Journal of Otolaryngology
Alex D Sweeney, Matthew L Carlson, Alejandro Rivas, Marc L Bennett, David S Haynes, George B Wanna
OBJECTIVE: To demonstrate the added value of magnetic resonance imaging (MRI) over computed tomography (CT) during adult cochlear implant evaluation. PATIENTS: Two adult patients are discussed in whom MRI studies diagnosed bilateral vestibular schwannomas during cochlear implant candidacy evaluation. INTERVENTIONS: Temporal bone CT and MRI. MAIN OUTCOME MEASURE: Diagnosis of NF2. RESULTS: Two adult patients, ages 67 and 68 years, were evaluated for cochlear implant candidacy...
May 2014: American Journal of Otolaryngology
Swee Tin Aw, Michael John Todd, Nadine Lehnen, Grace Elizabeth Aw, Konrad Peter Weber, Thomas Eggert, Gabor Michael Halmagyi
BACKGROUND: Vestibular reflexes, evoked by human electrical (galvanic) vestibular stimulation (EVS), are utilized to assess vestibular function and investigate its pathways. Our study aimed to investigate the electrically-evoked vestibulo-ocular reflex (eVOR) output after bilateral and unilateral vestibular deafferentations to determine the characteristics for interpreting unilateral lesions such as vestibular schwannomas. METHODS: EVOR was recorded with dual-search coils as binocular three-dimensional eye movements evoked by bipolar 100 ms-step at EVS intensities of [0...
2013: PloS One
Christopher A Schutt, John F Kveton
Intralabyrinthine schwannomas are rare tumors of the distal ends of the cochlear and vestibular nerve. Their presence can be debilitating secondary to symptoms of hearing loss, vertigo, tinnitus, and imbalance. Currently, treatment to restore hearing in those who have become profoundly deaf is not attempted. Additionally, resection in patients with functioning hearing is rare, as the surgery assures deafness. We report the first case demonstrating the feasibility of resection of an intralabyrinthine schwannoma with immediate cochlear implantation...
March 2014: American Journal of Otolaryngology
Georgios Mantokoudis, Michael C Schubert, Ali S Saber Tehrani, Aaron L Wong, Yuri Agrawal
OBJECTIVE: To describe vestibulo-ocular function in the immediate postoperative period after unilateral vestibular deafferentation from vestibular schwannoma resection. STUDY DESIGN: Prospective longitudinal study. SETTING: Tertiary medical center. PATIENTS: Five patients who underwent vestibular schwannoma resection via retrosigmoid approach. INTERVENTIONS: Bedside video-oculography and video head impulse testing (HIT)...
January 2014: Otology & Neurotology
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