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Propofol and PONV

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https://www.readbyqxmd.com/read/27825646/the-risk-of-postoperative-nausea-and-vomiting-between-surgical-patients-received-propofol-and-sevoflurane-anesthesia-a-matched-study
#1
Hideki Matsuura, Satoki Inoue, Masahiko Kawaguchi
OBJECTIVES: The current consensus guidelines for managing postoperative nausea and vomiting (PONV) suggest that one of anesthetic risk factors is the use of volatile anesthetics. However, in clinical settings, it is rare to perceive propofol to be superior to volatile anesthetics for the prevention of PONV. To assess whether PONV is related to the type of anesthetic delivered, we compared the incidence and duration of PONV between propofol anesthesia and sevoflurane anesthesia. METHODS: We performed a retrospective review of an institutional registry containing 21606 general anesthesia cases conducted following ethics board approval...
November 4, 2016: Acta Anaesthesiologica Taiwanica: Official Journal of the Taiwan Society of Anesthesiologists
https://www.readbyqxmd.com/read/27745793/comparison-of-different-hypotensive-anaesthesia-techniques-in-orthognathic-surgery-with-regard-to-intraoperative-blood-loss-quality-of-the-surgical-field-and-postoperative-nausea-and-vomiting
#2
S Lin, C Chen, C-F Yao, Y-A Chen, Y-R Chen
Sixty-three consecutive patients undergoing bimaxillary surgery between June and August 2015 were included in this study. Twenty-one patients were included in each of three study groups. In group 1, sevoflurane was the sole maintenance anaesthesia agent used; in group 2, propofol was the predominant agent, in addition to a reduced amount of sevoflurane; in group 3, patients received sevoflurane until fixation was completed, at which point it was switched to propofol. The mean intraoperative blood loss (ml) was 707...
October 10, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27650295/a-randomized-double-blind-trial-evaluating-the-efficacy-of-palonosetron-with-total-intravenous-anesthesia-using-propofol-and-remifentanil-for-the-prevention-of-postoperative-nausea-and-vomiting-after-gynecologic-surgery
#3
Yun-Sic Bang, Young Uk Kim, Dawoon Oh, Eui Yong Shin, Soo Kyoung Park
PURPOSE: Palonosetron has potent and long-acting antiemetic effects for postoperative nausea and vomiting (PONV). The aim of this study was to prospectively evaluate the efficacy of palonosetron when used with total intravenous anesthesia (TIVA) using propofol and remifentanil for the prevention of PONV in patients undergoing laparoscopic gynecologic surgery. METHODS: This prospective double-blind study comprised 100 female American Society of Anesthesiologist physical status I and II patients who were undergoing laparoscopic gynecologic surgery under TIVA...
September 20, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27454663/total-intravenous-anaesthesia-versus-single-drug-pharmacological-antiemetic-prophylaxis-in-adults-a-systematic-review-and-meta-analysis
#4
Maximilian S Schaefer, Peter Kranke, Stephanie Weibel, Robert Kreysing, Peter Kienbaum
BACKGROUND: Postoperative nausea and vomiting (PONV) are among the most unfavourable anaesthetic outcomes attributed to the administration of inhaled anaesthetics. Accordingly, inhaled anaesthetics are frequently substituted by propofol when patients are at risk of PONV. As, on some occasions, inhalational anaesthesia may be favourable, the relative impact of propofol anaesthesia needs to be established based on robust data. OBJECTIVE: To compare the effectiveness of a single-drug pharmacological prophylaxis with total intravenous anaesthesia (TIVA) for prevention of PONV...
October 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27307217/intra-operative-dexmedetomidine-reduces-early-postoperative-nausea-but-not-vomiting-in-adult-patients-after-gynaecological-laparoscopic-surgery-a-randomised-controlled-trial
#5
Zhi-Yu Geng, Ya-Fei Liu, Shan-Shan Wang, Dong-Xin Wang
BACKGROUND: Few studies have investigated the use of dexmedetomidine in patients with a high risk of postoperative nausea and vomiting (PONV) following gynaecological laparoscopic surgery. OBJECTIVE: To investigate if the intra-operative use of dexmedetomidine could reduce the incidence of PONV in this patient population. DESIGN: A randomised, double-blind, placebo-controlled trial. SETTING: A tertiary hospital in Beijing, China...
October 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27004303/target-controlled-infusion-versus-sevoflurane-desflurane-anesthesia-for-laparoscopic-cholecystectomy-comparison-postoperative-nausea-vomiting-and-extubation-time
#6
RANDOMIZED CONTROLLED TRIAL
Sumidtra Prathep, Sasithorn Mahattanaporn, Wirat Wasinwong
BACKGROUND: Target-controlled infusion (TCI) systems have been developed from manually controlled infusion systems and have rapidly increased in popularity, especially in laparoscopic surgery. Propofol is claimed to decrease nausea and vomiting. OBJECTIVE: To compare anesthetic techniques, propofol-TCI, desflurane, and sevoflurane, for better results in terms of postoperative nausea and vomiting (PONV) and extubation times. MATERIAL AND METHOD: The present study was prospective with informed consent from 75 patients, ASA 1-3 scheduled for laparoscopic cholecystectomy, and classified by anesthetic technique into three groups...
December 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/26866433/impact-of-prophylactic-combination-of-dexamethasone-ondansetron-on-postoperative-nausea-and-vomiting-in-obese-adult-patients-undergoing-laparoscopic-sleeve-gastrectomy-during-closed-loop-propofol-remifentanil-anaesthesia-a-randomised-double-blind-placebo-study
#7
Aurélien Bataille, Jacques-Florian Letourneulx, Alain Charmeau, Pascale Lemedioni, Philippe Léger, Thierry Chazot, Morgan Le Guen, Pierre Diemunsch, Marc Fischler, Ngai Liu
BACKGROUND: In obese patients, the incidence of postoperative nausea and vomiting (PONV) following sleeve gastrectomy under titration of total intravenous anaesthesia (TIVA) and the relevance of risk factors to indicate prophylaxis is unknown. OBJECTIVES: The hypothesis was that after automated TIVA, prophylaxis reduces PONV following laparoscopic sleeve gastrectomy. Our objective was to determine the incidence of PONV and evaluate the efficacy of dexamethasone and ondansetron as prophylaxis when automated intravenous anaesthesia is employed...
February 10, 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26658268/effect-of-total-intravenous-anaesthesia-and-prophylactic-ramosetron-on-postoperative-nausea-and-vomiting-after-thyroidectomy-a-prospective-randomized-controlled-study
#8
RANDOMIZED CONTROLLED TRIAL
Han Bum Joe, Sook Young Lee, Jin-Soo Kim, Hyuk Soo Chang, Yunyong Jeong, Haewon Jeong, Sung Yong Park
OBJECTIVE: To investigate the effect of combined prophylactic ramosetron and total intravenous anaesthesia (TIVA) on postoperative nausea and vomiting (PONV), compared with sevoflurane anaesthesia without prophylactic antiemetics, in female patients undergoing thyroidectomy. METHODS: Female patients were randomized between the sevoflurane group (anaesthesia maintained with sevoflurane) or TIVA + ramosetron group (TIVAR; 0.3 mg ramosetron just before anaesthesia induction, remifentanil and propofol anaesthesia)...
February 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/26550123/efficacy-of-dexmedetomidine-on-postoperative-nausea-and-vomiting-a-meta-analysis-of-randomized-controlled-trials
#9
Xiao Liang, Miao Zhou, Jiao-Jiao Feng, Liang Wu, Shang-Ping Fang, Xin-Yu Ge, Hai-Jing Sun, Peng-Cheng Ren, Xin Lv
PURPOSE: Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of the current meta-analysis was to assess the efficacy of dexmedetomidine on PONV. METHODS: Two researchers independently searched PubMed, Embase and Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs). The meta-analysis was performed with Review Manager. RESULTS: Eighty-two trials with 6,480 patients were included in this meta-analysis...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26446479/effects-of-dexmedetomidine-on-smooth-emergence-from-anaesthesia-in-elderly-patients-undergoing-orthopaedic-surgery
#10
RANDOMIZED CONTROLLED TRIAL
Dong Jun Kim, Sang Hun Kim, Keum Young So, Ki Tae Jung
BACKGROUND: Intraoperative dexmedetomidine may decrease postoperative emergence agitation in elderly patients due to its sedative effect. In this study, we evaluated the effect of adjuvant dexmedetomidine on smooth emergence from anaesthesia after orthopaedic surgery in elderly patients. METHODS: A total 115 patients (ASA I-II, aged over 65 years) were randomly allocated into four groups. Anaesthesia was maintained with either sevoflurane or total intravenous anaesthesia (TIVA) comprising propofol and remifentanil...
October 7, 2015: BMC Anesthesiology
https://www.readbyqxmd.com/read/26309498/efficacy-of-dexmedetomidine-on-postoperative-nausea-and-vomiting-a-meta-analysis-of-randomized-controlled-trials
#11
Xiao Liang, Miao Zhou, Jiao-Jiao Feng, Liang Wu, Shang-Ping Fang, Xin-Yu Ge, Hai-Jing Sun, Peng-Cheng Ren, Xin Lv
PURPOSE: Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of the current meta-analysis was to assess the efficacy of dexmedetomidine on PONV. METHODS: Two researchers independently searched PubMed, Embase and Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs). The meta-analysis was performed with Review Manager. RESULTS: Eighty-two trials with 6,480 patients were included in this meta-analysis...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26284410/-influence-of-dexamethasone-on-the-incidence-of-postoperative-nausea-and-vomiting-in-breast-cancer-patients-with-neoadjuvant-chemotherapy
#12
RANDOMIZED CONTROLLED TRIAL
Zhi-hong Li, Dan Liu, Zi-jing He, Zhi-yi Fan
OBJECTIVE: To evaluate the influence of dexamethasone on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing modified radical mastectomy with neoadjuvant chemotherapy. METHODS: In a prospective trial, 280 female (18-60 years) breast cancer patients undergoing modified radical mastectomy with neoadjuvent chemotherapy were randomized to two groups: one with dexamethasone (Group D) and one without dexamethasone (Group C, n=140). In each group, anesthesia was maintained with volatile anesthesia or total intravenous anesthesia (TIVA): TIVA (propofol) without dexamethasone (Subgroup CP); volatile anesthesia (sevoflurane) without dexamethasone (Subgroup CS); TIVA with 10 mg dexamethasone intravenously before anesthetic induction (Subgroup DP); volatile anesthesia with 10 mg dexamethasone intravenously before anesthetic induction (Subgroup DS)...
August 18, 2015: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/26273750/xenon-anesthesia-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
REVIEW
Lawrence Siu-Chun Law, Elaine Ah-Gi Lo, Tong Joo Gan
BACKGROUND: Xenon anesthesia has been studied for decades. However, no meta-analysis of randomized controlled trials (RCTs) on xenon anesthesia has been conducted. The aim of this study was to systematically review all available evidence from RCTs comparing xenon and other inhaled and IV anesthetics on anesthetic outcomes. Our meta-analysis attempted to quantify the effects of xenon anesthesia on clinical outcomes in relation to other anesthetics. METHODS: We found 43 RCTs from PubMed, MEDLINE, CENTRAL, EMBASE, and CINAHL (until January 2015)...
March 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/26079533/intra-and-postoperative-low-dose-ketamine-for-adolescent-idiopathic-scoliosis-surgery-a-randomized-controlled-trial
#14
R Minoshima, S Kosugi, D Nishimura, N Ihara, H Seki, T Yamada, K Watanabe, N Katori, S Hashiguchi, H Morisaki
BACKGROUND: In this randomized controlled trial, we examined whether intra- and postoperative infusion of low-dose ketamine decreased postoperative morphine requirement and morphine-related adverse effects as nausea and vomiting after scoliosis surgery. METHODS: After IRB approval and informed consent, 36 patients, aged 10-19 years, undergoing posterior correction surgery for adolescent idiopathic scoliosis, were randomly allocated into two groups: intra- and postoperative ketamine infusion at a rate of 2 μg/kg/min until 48 h after surgery (ketamine group, n = 17) or infusion of an equal volume of saline (placebo group, n = 19)...
November 2015: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/26001751/postoperative-recovery-after-anesthesia-in-morbidly-obese-patients-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Feng-Lin Liu, Yih-Giun Cherng, Shin-Yan Chen, Yen-Hao Su, Shih-Yu Huang, Po-Han Lo, Yen-Ying Lee, Ka-Wai Tam
PURPOSE: Obese patients present a challenge to safe general anesthesia because of impaired cardiopulmonary physiology and increased risks of aspiration and acute upper airway obstruction. Since studies are lacking regarding the postoperative effects on recovery from general anesthesia in morbidly obese patients, we conducted a systematic review and meta-analysis of recovery outcomes in morbidly obese patients who had undergone general anesthesia. SOURCE: We systematically searched the PubMed, EMBASE™, Cochrane, and Scopus™ databases for randomized controlled trials that evaluated the outcome of anesthesia with desflurane, sevoflurane, isoflurane, or propofol in morbidly obese patients...
August 2015: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/25931799/effects-of-%C3%A2%C2%B5-opioid-receptor-gene-polymorphism-on-postoperative-nausea-and-vomiting-in-patients-undergoing-general-anesthesia-with-remifentanil-double-blinded-randomized-trial
#16
RANDOMIZED CONTROLLED TRIAL
Seung-Hyun Lee, Joo-Dong Kim, Sol-Ah Park, Chung-Sik Oh, Seong-Hyop Kim
Association between postoperative nausea and vomiting (PONV) and µ-opioid receptor A118G single nucleotide polymorphism (SNP) is undefined and might underlie inconsistent results of studies on PONV occurrence in patients undergoing general anesthesia with the opioid, remifentanil. Four hundred and sixteen Korean women undergoing breast surgery with general anesthesia were randomized to receive remifentanil 10 ng/mL (plasma-site, Minto model) using a target-controlled infusion device and either propofol for total intravenous anesthesia (T group) or sevoflurane for inhalation anesthesia (I group) with bispectral index values maintained between 40 and 60...
May 2015: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/25892931/sevoflurane-versus-propofol-sedation-during-periocular-anesthetic-injections-in-oculoplastic-procedures-an-open-label-randomized-comparison
#17
Hatem A Tawfik, Mohsen Mostafa
PURPOSE: The purpose of the current investigation was to make an objective controlled comparison of pain tolerance, patient satisfaction and potential complications during the injection of local anesthesia in oculoplastic procedures under short-term sedation using inhalational versus parenteral sedatives. METHODS: This was an open-label, randomized clinical trial where patients were randomized to 3 groups. Group I: Sedation with intravenous propofol. Group II: Sedation with inhaled sevoflurane...
April 2015: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/25885989/comparison-of-recovery-profile-for-propofol-and-sevoflurane-anesthesia-in-cases-of-open-cholecystectomy
#18
Shiv Kumar Singh, Amit Kumar, Reena Mahajan, Surabhi Katyal, Sfurti Mann
OBJECTIVE: Sevoflurane and propofol are considered to be the agents of choice in surgeries of short duration due to their better recovery profile and few post-operative complications. This study was designed to compare the early recovery profile of sevoflurane and propofol anesthesia in patients undergoing open cholecystectomy. MATERIALS AND METHODS: A total of 60 patients of either sex with American Society of Anesthesiologists grade 1 and 2 scheduled for elective cholecystectomy were prospectively randomized into two groups...
September 2013: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/25885496/a-randomized-study-to-compare-the-efficacy-of-two-intravenous-fluid-regimens-of-normal-saline-on-the-incidence-of-postoperative-nausea-and-vomiting
#19
Ishwar Bhukal, N Srinivas, Sohan Lal Solanki, L N Yaddanapudi, Amit Jain
BACKGROUND: The purpose of this study was to evaluate the effect of two different volume of crystalloid given intraoperatively on postoperative nausea and vomiting (PONV). MATERIALS AND METHODS: Eighty adult patients of either sex belonging to ASA I and II class undergoing elective surgeries under general anesthesia for 1-2 h were studied in this prospective, randomized double blinded study. First group (group L) (n=40) received normal saline 4 mL/kg and second group (group H) (n=40) received 10 mL/kg of normal saline...
January 2012: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/25789261/prevention-of-postoperative-nausea-and-vomiting-with-a-subhypnotic-dose-of-propofol-in-patients-undergoing-lower-abdominal-surgery-a-prospective-randomized-double-blind-study
#20
Khosrou Naghibi, Parviz Kashefi, Hamed Azarnoush, Parisa Zabihi
BACKGROUND: Postoperative nausea and vomiting (PONV) is a common complication after general anesthesia in patients undergoing elective lower abdominal surgery. We aimed to compare the effect of a sub hypnotic dose of Propofol in the prevention of PONV after lower abdominal surgery with that of the conventional antiemetic drug Metoclopramide. MATERIALS AND METHODS: In this prospective, randomized, double-blind, placebo-controlled study, 104 patients with American Society of Anesthesiologists (ASA) class I or II status, aged 18-65 years, and undergoing elective lower abdominal surgery were randomized to one of four groups (n = 26 each)...
2015: Advanced Biomedical Research
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