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https://www.readbyqxmd.com/read/28261848/impact-of-physical-activity-on-patient-self-reported-outcomes-of-lifelong-premature-ejaculation-patients-results-of-a-prospective-randomised-sham-controlled-trial
#1
M F Kilinc, Y Aydogmus, Y Yildiz, O G Doluoglu
Previous studies have investigated whether physical activity increases serotonin hormone levels. Serotonin receptor dysfunction is one of the frequently accused factors of premature ejaculation (PE). Nevertheless, no studies up to date have demonstrated that the association between physical activity and premature ejaculation. We aimed to investigate the relationship between physical activity and PE and determine whether moderate physical activity might delay ejaculation time or be an alternative treatment for PE...
March 6, 2017: Andrologia
https://www.readbyqxmd.com/read/28248021/-new-data-on-the-effectiveness-of-tadalafil-alone-and-in-combination-with-neyrodoz-in-treating-erectile-dysfunction-associated-with-secondary-premature-ejaculation
#2
N D Akhvlediani, I P Matyukhov
AIM: To compare the effectiveness of the phosphodiesterase type 5 inhibitor (PDE-5i) tadalafil alone and in combination with a biologically active dietary supplement (BADS) NeyroDoz, containing the precursors of serotonin in patients with erectile dysfunction (ED) associated with secondary premature ejaculation (SPE). MATERIAL AND METHODS: 105 patients (mean age 36.2+/-9.1 years) with concomitant ED and SPE were included in a prospective study and divided into 2 groups...
November 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247326/reconstructive-management-options-of-delayed-complications-following-bladder-outlet-surgery
#3
REVIEW
Nora Baker, Carmen Tong, Jay Simhan
PURPOSE OF REVIEW: Technological advancements in urologic endoscopy within the last decades have improved outcomes following bladder outlet reduction surgery while minimizing risks of short- and intermediate-term complications. This review aims to examine late complications of endoscopic reduction of the prostate and the various treatment options available. RECENT FINDINGS: Urinary incontinence, ejaculatory dysfunction, urethral strictures, bladder neck contractures, and fistula formations are the most common delayed complications following bladder outlet reduction surgery...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28228879/zinner-syndrome-diagnosed-by-magnetic-resonance-imaging-and-computed-tomography-role-of-imaging-to-identify-and-evaluate-the-uncommon-variation-in-development-of-the-male-genital-tract
#4
V Fiaschetti, L Greco, V Giuricin, D De Vivo, E Di Caprera, R Di Trapano, F Castellani, R Floris
Seminal vesicle cysts are a very rare condition and its often associated with ipsilateral renal agenesis. The diagnosis of seminal vesicle cysts may be delayed or missed because of the non-specific symptoms of this condition. This article reports a triad of right renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction (Zinner syndrome) in a 56 years old man.
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28224697/antioxidant-treatment-ameliorates-diabetes-induced-dysfunction-of-the-vas-deferens-in-a-rat-model
#5
P Tsounapi, M Honda, F Dimitriadis, S Shimizu, T Shiomi, K Hikita, M Saito, S Tomita, N Sofikitis, A Takenaka
Diabetes mellitus (DM) affects the male ejaculatory function. This study was designed to evaluate the role of oxidative stress in the development of diabetes-induced dysfunction of vas deferens (VD) in the rat. DM was induced by streptozotocin in 40 male Wistar rats. Subsequently, the diabetic animals were divided into three groups: DM group, DM + Eda group and DM + Tau group. These groups were administered saline, edaravone and taurine, respectively, daily for 4 weeks. Another group of ten rats served as a control group...
February 22, 2017: Andrologia
https://www.readbyqxmd.com/read/28218041/guibourtia-tessmannii-induced-fictive-ejaculation-in-spinal-male-rat-involvement-of-d1-d2-like-receptors
#6
Patrick Brice Deeh Defo, Elvis Asongu, Modeste Nya Wankeu, Esther Ngadjui, Georges Romeo Bonsou Fazin, François Xavier Kemka, Miguel Carro-Juarez, Albert Kamanyi, Pierre Kamtchouing, Pierre Watcho
CONTEXT: Guibourtia tessmannii (Caesalpiniaceae) is a plant traditionally used as aphrodisiac. We previously reported the pro-ejaculatory effects of the aqueous and methanol extracts of G. tesmannii in spinal male rat. However, the mechanism underlying such effects has not been elucidated. OBJECTIVE: This study characterizes the dopaminergic sub-type receptors involved in G. tesmannii-induced ejaculation in male Wistar rat. MATERIALS AND METHODS: Urethane-anesthetized spinal male rats were intravenously treated with saline solution (1 mL/kg, control); dopamine (0...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28217932/the-relationship-between-the-second-to-fourth-digit-ratios-and-lifelong-premature-ejaculation-a-prospective-comparative-study
#7
D Bolat, G U Kocabas, T Kose, T Degirmenci, M E Aydin, C Dincel
To investigate the relationship between the fetal androgen exposure and lifelong premature ejaculation by using the ratio of the second (index)-to-fourth (ring) digits (2D : 4D) which is the marker for higher prenatal androgen exposure. Totally 65 patients with lifelong premature ejaculation and 65 control cases without any ejaculatory complaints were enrolled in the study. A detailed medical history was obtained and self-estimated intravaginal ejaculatory latency times were recorded. Ejaculation function was evaluated by Premature Ejaculation Diagnostic Tool...
February 19, 2017: Andrology
https://www.readbyqxmd.com/read/28179637/the-relationship-between-acquired-premature-ejaculation-and-metabolic-syndrome-a-prospective-comparative-study
#8
D Bolat, G U Kocabas, B Gunlusoy, O Aydogdu, M E Aydin
The aim of this study was to investigate the relationship between metabolic syndrome (MetS) and acquired premature ejaculation (PE). A total of 100 patients with acquired PE and 100 control cases were enrolled in the study. After obtaining a detailed medical history, anthropometric (weight, height and waist circumference) and blood pressure measurements were performed. Ejaculation and erection functions were evaluated by Premature Ejaculation Diagnostic Tool (PEDT) and International Index of Erectile Function-5 (IIEF-5), respectively...
February 9, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28167337/profiles-of-brain-central-nervous-system-gene-expression-associated-with-ejaculation-behavior-in-male-rats
#9
Xijun Qin, Xiaojun Ma, Jianhui Liang, Dongping Tu, Zuliang Luo, Jie Huang, Changming Mo
The male rat has been used extensively as a model for evaluating the neurophysiology of sexual behavior. However, gene expression in the brain throughout the process of sexual intercourse has yet to be elucidated. In the present study, we created a transcriptomic BodyMap by performing mRNA-Seq on brain samples from pre-copulatory control (CK), fourth intromission (CR4), ejaculation (EJ) and post-ejaculatory interval 1-min (PEI1) Sprague Dawley rats (n=40, all male, each 10). The resulting analysis generated an average of approximately 47 million sequence reads, indicating changes in roughly 21,255 genes for each sample...
May 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28161008/genito-urinary-sequelae-after-carcinological-rectal-resection-what-to-tell-patients-in-2017
#10
A Abdelli, X Tillou, A Alves, B Menahem
Although we have seen revolutionary changes with multi-disciplinary management of patients with rectal cancer, the evaluation of genito-urinary sequelae remains of great concern. Precise pre-operative evaluation with validated scores allows detection of urinary disorders in 16 to 23% of patients, and sexual disorders in nearly 35% of men and 50% of women. Regardless of the surgical approach, it is fundamental to respect the autonomic innervation during total mesorectal excision in order to prevent these sequelae...
February 1, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/28160849/aphrodisiac-activity-of-phlegmariurus-saururus-in-copulating-and-noncopulating-male-rats
#11
Marcela Birri, Mariana Vallejo, Miguel Carro-Juárez, A Mariel Agnese
BACKGROUND: Phlegmariurus saururus is popularly known in Argentina as aphrodisiac. For this reason, it was previously investigated and determined that the decoction of this plant elicits pro-ejaculatory activity and increases the ejaculatory potency in the Fictive Ejaculation Model. HYPOTHESIS/PURPOSE: the decoction of P. saururus facilitates sexual behavior in sexually experienced male rat and induces copulatory behavior in non-copulating male rats. METHODS: The extraction method (decoction) was validated through Selectivity, Accuracy and Precision, by identification of the majority alkaloids, expressed as sauroxine...
January 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28097620/seminal-tract-amyloidosis-synchronous-amyloidosis-of-the-seminal-vesicles-deferent-ducts-and-ejaculatory-ducts
#12
Lea Rath-Wolfson, Golan Bubis, Shmuel Shtrasburg, Asaf Shvero, Rumelia Koren
Senile Seminal Vesicle Amyloidosis (SSVA) increases with age. Involvement of the whole seminal tract, i.e. the seminal vesicles, ejaculatory and deferent ducts was first reported by us in the International Symposium on Amyloidosis 1998. Since then we encountered four more cases of SSVA. In all these cases the ejaculatory and deferent ducts were also involved by amyloid. The amyloid was located mostly sub-epithelially, stained positively with Congo red, gave green birefringence under polarized light and was permanganate sensitive, slightly positive for lactoferrin immunostaining and negative for all known amyloid types...
January 17, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28089730/chronic-prostate-inflammation-predicts-symptom-progression-in-chronic-prostatitis-chronic-pelvic-pain-cp-cpps-patients
#13
J Curtis Nickel, Stephen J Freedland, Ramiro Castro-Santamaria, Daniel M Moreira
OBJECTIVE: This report examines the 4-year longitudinal association between histological prostate inflammation and CP/CPPS, development of new and progression of existing CP/CPPS, in the men randomized to placebo in the REDUCE population. METHODS: Uni- and multivariable analyses at multiple time points over 4 years were performed between acute and chronic inflammation detected on baseline biopsies and incidence of CPPS-like symptoms (defined as a positive response to CPSI question 1a [perineal pain] and/or question 2b [ejaculatory pain], and a total pain subscore of at least 4) and progression of CP/CPPS (defined as an increase ≥ 4 points from baseline total CPSI score in patients with a baseline categorization of CP/CPPS)...
January 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28088261/parquetina-nigrescens-leaves-chemical-profile-and-influence-on-the-physical-and-biochemical-indices-of-sexual-activity-of-male-wistar-rats
#14
Omowumi Titilola Kayode, Musa Toyin Yakubu
OBJECTIVE: The leaves of Parquetina nigrescens have been claimed in folk medicine to be useful for managing sexual dysfunction, but there is inadequate scientific evidence for this claim. This investigation was conducted to assess the effects of aqueous leaf extract of Parquetina nigrescens (AEPN) in rats induced with sexual dysfunction. METHODS: Male rats were allocated into various groups after being induced into sexual dysfunction with paroxetine hydrochloride...
January 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28087922/urogenital-tuberculosis
#15
André A Figueiredo, Antônio M Lucon, Miguel Srougi
Urogenital tuberculosis is the second most frequent form of extrapulmonary tuberculosis. Starting with a pulmonary focus, 2 to 20% of patients develop urogenital tuberculosis through hematogenous spread to the kidneys, prostate, and epididymis; through the descending collecting system to the ureters, bladder, and urethra; and through the ejaculatory ducts to the genital organs. Urogenital tuberculosis occurs at all age ranges, but it is predominant in males in their fourth and fifth decades. It is a serious, insidious disease, generally developing symptoms only at a late stage, which leads to a diagnostic delay with consequent urogenital organ destruction; there are reports of patients with renal failure as their initial clinical presentation...
January 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28065363/relationship-between-amyloid-precursor-protein-in-seminal-plasma-and-abnormal-penile-sympathetic-skin-response-in-lifelong-premature-ejaculation
#16
Zhiwei Hong, Yuming Feng, Hualong Ding, Xuechun Hu, Jin-Chun Lu, Xie Ge, Yifeng Ge, Bing Yao
INTRODUCTION: Hyperactivity of the sympathetic nervous system can play an important role in lifelong premature ejaculation (PE). Our previous study found that amyloid precursor protein (APP) levels in seminal plasma of patients with PE were clearly increased. Amyloid-β (Aβ) is derived from APP. Excessive Aβ, especially Aβ42, can cause neuronal dysfunction. AIM: To determine whether APP and Aβ42 are associated with an abnormal penile sympathetic skin response (PSSR)...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28060836/diagnosis-of-partial-retrograde-ejaculation-in-non-azoospermic-infertile-men-with-low-semen-volume
#17
Roger Mieusset, Marie Walschaerts, François Isus, Thierry Almont, Myriam Daudin, Safouane M Hamdi
In non-azoospermic patients with low semen volume (LSV), looking for partial retrograde ejaculation (PRE) by searching sperm in the postejaculatory urine (PEU) is required. The use of a retro-ejaculatory index (R-ratio) was suggested to define PRE, but none of the studies indicated a specific threshold above which PRE must be considered. Our objective was to propose a threshold value for the R-ratio as indicative of PRE in patients with LSV selected to be devoid of any known causes or risk factors for retrograde ejaculation or LSV...
2017: PloS One
https://www.readbyqxmd.com/read/28041925/complementary-and-alternative-medicine-for-management-of-premature-ejaculation-a-systematic-review
#18
REVIEW
Katy Cooper, Marrissa Martyn-St James, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Shijie Ren, Kevan Wylie, Leila Frodsham, Catherine Hood
INTRODUCTION: Premature ejaculation (PE) is defined as ejaculation within 1 minute (lifelong PE) or 3 minutes (acquired PE), inability to delay ejaculation, and negative personal consequences. Management includes behavioral and pharmacologic approaches. AIM: To systematically review effectiveness, safety, and robustness of evidence for complementary and alternative medicine in managing PE. METHODS: Nine databases including Medline were searched through September 2015...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28041923/prevalence-and-associated-factors-of-premature-ejaculation-in-the-anhui-male-population-in-china-evidence-based-unified-definition-of-lifelong-and-acquired-premature-ejaculation
#19
Jingjing Gao, Dangwei Peng, Xiansheng Zhang, Zongyao Hao, Jun Zhou, Song Fan, Yao Zhang, Jun Mao, Xianming Dou, Chaozhao Liang
INTRODUCTION: In 2014, new evidence-based definitions of lifelong premature ejaculation (LPE) and acquired premature ejaculation (APE) were proposed by the International Society for Sexual Medicine. Based on the new PE definitions, the prevalence of and factors associated with LPE and APE have not been investigated in China. AIM: To evaluate the prevalence of and factors associated with LPE and APE in men with the complaint of PE in China. METHODS: From December 2011 to December 2015, a cross-sectional field survey was conducted in five cities in the Anhui province of China...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28003018/prostatic-urethra-malformation-associated-with-retrograde-ejaculation-a-case-report
#20
Kai Zhao, Jianzhong Zhang, Aiming Xu, Cheng Zhang, Zengjun Wang
BACKGROUND: Retrograde ejaculation can have anatomical, neurogenic, or pharmacological causes. Among these factors, malformation of the prostatic urethra is an uncommon cause. CASE PRESENTATION: We describe a 29-year-old Han Chinese man with absence of his verumontanum combined with ejaculatory duct cysts, and no other cause for ejaculatory dysfunction. His verumontanum was replaced by a deep groove adjacent to his bladder neck, which could significantly influence bladder neck contraction...
December 21, 2016: Journal of Medical Case Reports
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