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https://www.readbyqxmd.com/read/28097620/seminal-tract-amyloidosis-synchronous-amyloidosis-of-the-seminal-vesicles-deferent-ducts-and-ejaculatory-ducts
#1
Lea Rath-Wolfson, Golan Bubis, Shmuel Shtrasburg, Asaf Shvero, Rumelia Koren
Senile Seminal Vesicle Amyloidosis (SSVA) increases with age. Involvement of the whole seminal tract, i.e. the seminal vesicles, ejaculatory and deferent ducts was first reported by us in the International Symposium on Amyloidosis 1998. Since then we encountered four more cases of SSVA. In all these cases the ejaculatory and deferent ducts were also involved by amyloid. The amyloid was located mostly sub-epithelially, stained positively with Congo red, gave green birefringence under polarized light and was permanganate sensitive, slightly positive for lactoferrin immunostaining and negative for all known amyloid types...
January 17, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28089730/chronic-prostate-inflammation-predicts-symptom-progression-in-chronic-prostatitis-chronic-pelvic-pain-cp-cpps-patients
#2
J Curtis Nickel, Stephen J Freedland, Ramiro Castro-Santamaria, Daniel M Moreira
OBJECTIVE: This report examines the 4-year longitudinal association between histological prostate inflammation and CP/CPPS, development of new and progression of existing CP/CPPS, in the men randomized to placebo in the REDUCE population. METHODS: Uni- and multivariable analyses at multiple time points over 4 years were performed between acute and chronic inflammation detected on baseline biopsies and incidence of CPPS-like symptoms (defined as a positive response to CPSI question 1a [perineal pain] and/or question 2b [ejaculatory pain], and a total pain subscore of at least 4) and progression of CP/CPPS (defined as an increase ≥ 4 points from baseline total CPSI score in patients with a baseline categorization of CP/CPPS)...
January 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28088261/parquetina-nigrescens-leaves-chemical-profile-and-influence-on-the-physical-and-biochemical-indices-of-sexual-activity-of-male-wistar-rats
#3
Omowumi Titilola Kayode, Musa Toyin Yakubu
OBJECTIVE: The leaves of Parquetina nigrescens have been claimed in folk medicine to be useful for managing sexual dysfunction, but there is inadequate scientific evidence for this claim. This investigation was conducted to assess the effects of aqueous leaf extract of Parquetina nigrescens (AEPN) in rats induced with sexual dysfunction. METHODS: Male rats were allocated into various groups after being induced into sexual dysfunction with paroxetine hydrochloride...
January 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28087922/urogenital-tuberculosis
#4
André A Figueiredo, Antônio M Lucon, Miguel Srougi
Urogenital tuberculosis is the second most frequent form of extrapulmonary tuberculosis. Starting with a pulmonary focus, 2 to 20% of patients develop urogenital tuberculosis through hematogenous spread to the kidneys, prostate, and epididymis; through the descending collecting system to the ureters, bladder, and urethra; and through the ejaculatory ducts to the genital organs. Urogenital tuberculosis occurs at all age ranges, but it is predominant in males in their fourth and fifth decades. It is a serious, insidious disease, generally developing symptoms only at a late stage, which leads to a diagnostic delay with consequent urogenital organ destruction; there are reports of patients with renal failure as their initial clinical presentation...
January 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28065363/relationship-between-amyloid-precursor-protein-in-seminal-plasma-and-abnormal-penile-sympathetic-skin-response-in-lifelong-premature-ejaculation
#5
Zhiwei Hong, Yuming Feng, Hualong Ding, Xuechun Hu, Jin-Chun Lu, Xie Ge, Yifeng Ge, Bing Yao
INTRODUCTION: Hyperactivity of the sympathetic nervous system can play an important role in lifelong premature ejaculation (PE). Our previous study found that amyloid precursor protein (APP) levels in seminal plasma of patients with PE were clearly increased. Amyloid-β (Aβ) is derived from APP. Excessive Aβ, especially Aβ42, can cause neuronal dysfunction. AIM: To determine whether APP and Aβ42 are associated with an abnormal penile sympathetic skin response (PSSR)...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28060836/diagnosis-of-partial-retrograde-ejaculation-in-non-azoospermic-infertile-men-with-low-semen-volume
#6
Roger Mieusset, Marie Walschaerts, François Isus, Thierry Almont, Myriam Daudin, Safouane M Hamdi
In non-azoospermic patients with low semen volume (LSV), looking for partial retrograde ejaculation (PRE) by searching sperm in the postejaculatory urine (PEU) is required. The use of a retro-ejaculatory index (R-ratio) was suggested to define PRE, but none of the studies indicated a specific threshold above which PRE must be considered. Our objective was to propose a threshold value for the R-ratio as indicative of PRE in patients with LSV selected to be devoid of any known causes or risk factors for retrograde ejaculation or LSV...
2017: PloS One
https://www.readbyqxmd.com/read/28041925/complementary-and-alternative-medicine-for-management-of-premature-ejaculation-a-systematic-review
#7
REVIEW
Katy Cooper, Marrissa Martyn-St James, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Shijie Ren, Kevan Wylie, Leila Frodsham, Catherine Hood
INTRODUCTION: Premature ejaculation (PE) is defined as ejaculation within 1 minute (lifelong PE) or 3 minutes (acquired PE), inability to delay ejaculation, and negative personal consequences. Management includes behavioral and pharmacologic approaches. AIM: To systematically review effectiveness, safety, and robustness of evidence for complementary and alternative medicine in managing PE. METHODS: Nine databases including Medline were searched through September 2015...
December 29, 2016: Sexual Medicine
https://www.readbyqxmd.com/read/28041923/prevalence-and-associated-factors-of-premature-ejaculation-in-the-anhui-male-population-in-china-evidence-based-unified-definition-of-lifelong-and-acquired-premature-ejaculation
#8
Jingjing Gao, Dangwei Peng, Xiansheng Zhang, Zongyao Hao, Jun Zhou, Song Fan, Yao Zhang, Jun Mao, Xianming Dou, Chaozhao Liang
INTRODUCTION: In 2014, new evidence-based definitions of lifelong premature ejaculation (LPE) and acquired premature ejaculation (APE) were proposed by the International Society for Sexual Medicine. Based on the new PE definitions, the prevalence of and factors associated with LPE and APE have not been investigated in China. AIM: To evaluate the prevalence of and factors associated with LPE and APE in men with the complaint of PE in China. METHODS: From December 2011 to December 2015, a cross-sectional field survey was conducted in five cities in the Anhui province of China...
December 29, 2016: Sexual Medicine
https://www.readbyqxmd.com/read/28003018/prostatic-urethra-malformation-associated-with-retrograde-ejaculation-a-case-report
#9
Kai Zhao, Jianzhong Zhang, Aiming Xu, Cheng Zhang, Zengjun Wang
BACKGROUND: Retrograde ejaculation can have anatomical, neurogenic, or pharmacological causes. Among these factors, malformation of the prostatic urethra is an uncommon cause. CASE PRESENTATION: We describe a 29-year-old Han Chinese man with absence of his verumontanum combined with ejaculatory duct cysts, and no other cause for ejaculatory dysfunction. His verumontanum was replaced by a deep groove adjacent to his bladder neck, which could significantly influence bladder neck contraction...
December 21, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28002640/activation-of-galanin-and-cholecystokinin-receptors-in-the-lumbosacral-spinal-cord-is-required-for-ejaculation-in-male-rats
#10
Natalie Kozyrev, Lique M Coolen
The spinal ejaculation generator is comprised of lumbar spinothalamic (LSt) cells and their axonal projections to autonomic and motor neurons in the lumbosacral spinal cord. LSt cells regulate ejaculatory reflexes by release of neuropeptides that are co-expressed in their axons, as previously demonstrated for gastrin releasing peptide and enkephalin. Here, the role of two other neuropeptides co-expressed in LSt cells for ejaculatory reflexes are demonstrated: galanin and cholecystokinin (CCK). Adult male rats were anesthetized, spinalized, and received intrathecal infusions of galanin receptor antagonist Galantide (1 or 10 nmol) or CCK receptor antagonist proglumide (71 or 714 nmol)...
December 21, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27938992/sexual-sensation-seeking-sexual-compulsivity-and-gender-identity-and-its-relationship-with-sexual-functioning-in-a-population-sample-of-men-and-women
#11
Andrea Burri
INTRODUCTION: Despite awareness of the importance of psycho-affective factors in the development of sexual problems, there is a lack of studies exploring the relation of sexual sensation seeking (SSS) and sexual compulsivity (SC) to sexual functioning. Because sex differences in SSS and SC have been reported, gender identity (GI; an individual's own experience of his or her gender that is unrelated to the actual biological sex) might act as a moderator in this relation. AIM: To understand the role of SSS and SC for men and women's sexual functioning and to explore whether these potential associations are moderated by GI...
December 6, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27929243/epididymitis-an-overview
#12
John R McConaghy, Bethany Panchal
Inflammation of the epididymis, or epididymitis, is commonly seen in the outpatient setting. Etiology and treatment are based on patient age and the likely causative organisms. Epididymitis presents as the gradual onset of posterior scrotal pain that may be accompanied by urinary symptoms such as dysuria and urinary frequency. Physical findings include a swollen and tender epididymis with the testis in an anatomically normal position. Although the etiology is largely unknown, reflux of urine into the ejaculatory ducts is considered the most common cause of epididymitis in children younger than 14 years...
November 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27920851/zinner-syndrome-a-rare-developmental-anomaly-of-the-mesonephric-duct-diagnosed-on-magnetic-resonance-imaging
#13
Shibani Mehra, Rajeev Ranjan, Umesh Chandra Garga
Developmental anomalies of the urogenital tract are rare but often encountered. Zinner's syndrome is a rare congenital abnormality of mesonephric (Wolffian) duct consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction due to developmental arrest in early embryogenesis affecting the caudal end of Mullerian duct and only approximately a 100 cases have been reported so far. Radiologic modalities such as intravenous pyelography, ultrasonography, vasovesiculography, contrast enhanced computed tomography, and magnetic resonance imaging are all helpful in diagnosis of this unusual entity...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27920841/wolffian-origin-of-vagina-unfolds-the-embryopathogenesis-of-ohvira-obstructed-hemivagina-and-ipsilateral-renal-anomaly-syndrome-and-places-ohvira-as-a-female-counterpart-of-zinner-syndrome-in-males
#14
Yashant Aswani, Ravi Varma, Pradeep Choudhary, Reeta B Gupta
BACKGROUND: The classical theory of Müllerian origin of upper vagina fails to explain complex urogenital malformations like OHVIRA syndrome; the Acien's hypothesis, however, unravels the hidden embryopathogenesis. As per Acien, Wolffian (mesonephric) ducts instead of Müllerian ducts and sinovaginal bulbs, give rise to the vagina. The new hypothesis, however, retains the concept of origin of the ureters (with ureters inducing renal development) by the former and the uterus by Müllerian ducts...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27917533/human-spinal-ejaculation-generator
#15
Clément Chéhensse, Patricia Facchinetti, Stéphane Bahrami, Philippe Andrey, Jean-Marc Soler, Fabrice Chrétien, Jacques Bernabé, Pierre Clément, Pierre Denys, François Giuliano
OBJECTIVE: A spinal ejaculation generator (SEG) has been identified in the rat with lumbar galaninergic interneurons playing a pivotal role (Science 2002;297:1566-1569). The aim was to evidence a SEG in humans. METHODS: Spatial distribution of galaninergic neurons was studied in postmortem spinal cord segments of 6 men and compared with that of 6 women for evidencing sexual dimorphism. Based on the identified segmental distribution of galaninergic neurons, the ability for penile vibratory stimulation (PVS) to elicit ejaculation when the concerned spinal segments were injured was studied in 384 patients with clinically complete spinal cord injury (SCI) and consequent anejaculation...
December 5, 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27914562/standards-for-clinical-trials-in-male-and-female-sexual-dysfunction-ii-patient-reported-outcome-measures
#16
William A Fisher, Ilan Gruenwald, Emmanuele A Jannini, Ahinoam Lev-Sagie, Lior Lowenstein, Robert E Pyke, Yakov Reisman, Dennis A Revicki, Eusebio Rubio-Aurioles
The second article in this series, Standards for Clinical Trials in Male and Female Sexual Dysfunction, focuses on measurement of patient-reported outcomes (PROs). Together with the design of appropriate phase I to phase IV clinical trials, the development, validation, choice, and implementation of valid PRO measurements-the focus of the present article-form the foundation of research on treatments for male and female sexual dysfunctions. PRO measurements are assessments of any aspect of a patient's health status that come directly from the patient (ie, without the interpretation of the patient's responses by a physician or anyone else)...
December 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27900222/surgical-outcomes-and-complications-of-tube%C3%A2-promedon-malleable-penile-prostheses-in-diabetic-versus-non-diabetic-patients-with-erectile-dysfunction
#17
Elnisr Rashed Mohamed, Ahmed Rashed Hammady, Mohamed Zaki Eldahshoury, Ahmed Mamdouh Elsharkawi, Ahmed Mahmoud Riad, Hazem Mohamed Elmogazy, Mohamed Mostafa Hussien, Wael Mohamed Gamal
OBJECTIVE: To evaluate surgical outcome, complications, and patients satisfaction with the Tube® (Promedon, Cordoba, Argentina) malleable penile prosthesis in diabetic and non-diabetic patients with refractory erectile dysfunction (ED). PATIENTS AND METHODS: The records of 128 eligible patients who received Tube malleable penile prostheses at our institute between September 2008 and October 2015 were reviewed. RESULTS: Of the 128 patients, who received Tube penile prostheses at our institute, 53 were diabetics and 75 were non-diabetics...
December 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27887927/effects-of-in-vitro-acute-and-chronic-treatment-with-fluoxetine-on-the-sympathetic-neurotransmission-of-rat-vas-deferens
#18
Shaista Poppe Pedroso, Bruno Palmieri de Souza, Aron Jurkiewicz, Neide H Juriewicz, Edilson Dantas da Silva Junior
It is described that fluoxetine treatment is able to induce ejaculatory disorders. However, the exact mechanism is still not fully understood. Therefore, this study was carried out to further evaluate the anti-ejaculatory effects of fluoxetine, using different approaches (in vitro or in vivo treatments), on the sympathetic neurotransmission of the rat vas deferens. Vas deferens from male Wistar rats were used to check the in vitro effects of fluoxetine 10(-6)M, 3.10(-6)M or 10(-5)M. Animals were also acutely (20mg/kg, i...
November 20, 2016: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/27882592/ureterorenoscopy-with-stenting-and-its-effect-on-male-sexual-function-a-controlled-randomised-prospective-study
#19
M S Bolat, E Akdeniz, R Asci, F Erdemir, O Cinar, L Tomak
Seventy-two male patients, who were included in this study, underwent ureteroscopic stone surgery (study group). Forty-two healthy males were enrolled as control group. Changes in sexual function were evaluated using International Index of Erectile Function questionnaire in pre-operative, first and third postoperative terms. Overall satisfaction in relation to the age, operation time, presence of stents, body mass index, educational status, previous operations, International Index of Erectile Function score, International Prostate Symptom Score, Quality of Life, income status, Male Sexual Health Questionnaire, stone-free rates and Beck's depression scale were evaluated...
November 23, 2016: Andrologia
https://www.readbyqxmd.com/read/27875946/the-role-of-sexual-dysfunction-and-infertility-on-reproductive-health-in-diabetics-pathogenesis-evaluation-and-management
#20
Jason Gandhi, Gautam Dagur, Kelly Warren, Noel Smith, Sardar Ali Khan
BACKGROUND: Uncontrolled or long-term diabetes mellitus is conducive to vascular and oxidative stress disturbances that impede several physiological systems, which may in turn elicit psychological symptoms. OBJECTIVE: We assess the sexual and hormonal complications of diabetes mellitus that impair reproductive function in males and females. METHOD: A comprehensive MEDLINE® search was guided using key words relevant to diabetes mellitus and reproductive health...
November 22, 2016: Current Diabetes Reviews
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