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https://www.readbyqxmd.com/read/28430975/behavioral-response-of-the-brown-marmorated-stink-bug-hemiptera-pentatomidae-to-semiochemicals-deployed-inside-and-outside-anthropogenic-structures-during-the-overwintering-period
#1
William R Morrison, Angelita Acebes-Doria, Emily Ogburn, Thomas P Kuhar, James F Walgenbach, J Christopher Bergh, Louis Nottingham, Anthony Dimeglio, Patricia Hipkins, Tracy C Leskey
The brown marmorated stink bug, Halyomorpha halys (Stål), is an invasive species from Asia capable of causing severe agricultural damage. It can also be a nuisance pest when it enters and exits anthropogenic overwintering sites. In recent years, pheromone lures and traps for H. halys have been developed and used to monitor populations in field studies. To date, no study has investigated the applicability of these monitoring tools for use indoors by building residents during the overwintering period. Herein, we 1) assessed when in late winter (diapause) and spring (postdiapause) H...
April 20, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28430591/poly-adenosine-diphosphate-ribose-polymerase-as-therapeutic-target-lessons-learned-from-its-inhibitors
#2
REVIEW
Anna Mária Cseh, Zsolt Fábián, Balázs Sümegi, Luca Scorrano
Poly(ADP-ribose) polymerases are a family of DNA-dependent nuclear enzymes catalyzing the transfer of ADP-ribose moieties from cellular nicotinamide-adenine-dinucleotide to a variety of target proteins. Although they have been considered as resident nuclear elements of the DNA repair machinery, recent works revealed a more intricate physiologic role of poly(ADP-ribose) polymerases with numerous extranuclear activities. Indeed, poly(ADP-ribose) polymerases participate in fundamental cellular processes like chromatin remodelling, transcription or regulation of the cell-cycle...
April 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28429902/validity-and-practicability-of-smartphone-based-photographic-food-records-for-estimating-energy-and-nutrient-intake
#3
Kaimeng Kong, Lulu Zhang, Lisu Huang, Yexuan Tao
BACKGROUND AND OBJECTIVES: Image-assisted dietary assessment methods are frequently used to record individual eating habits. This study tested the validity of a smartphone-based photographic food recording approach by comparing the results obtained with those of a weighed food record. We also assessed the practicality of the method by using it to measure the energy and nutrient intake of college students. METHODS AND STUDY DESIGN: The experiment was implemented in two phases, each lasting 2 weeks...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28426222/structural-and-dynamical-properties-of-tetra-alkyl-ammonium-bromide-aqueous-solutions-a-molecular-dynamics-simulation-study-using-a-polarizable-force-field
#4
Dengpan Dong, Justin B Hooper, Dmitry Bedrov
Understanding the behavior of aqueous solutions containing tetra-alkyl ammonium (TAA) cations is of great significance in a number of applications, including polymer membranes for fuel cells. In this work, a polarizable force field has been used to preform atomistic molecular dynamics (MD) simulations of aqueous solutions containing tetra-methyl ammonium (TMA) or tetra-butyl ammonium (TBA) cations and Br counterions. Extensive MD simulations of TMA-Br/water and TBA-Br/water systems were conducted as a function of solution composition (ion pair : water molar ratios of 1:10, 1:20, 1:30, 1:63, 1:500) at atmospheric pressure and 298K...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28421875/three-dimensional-printing-and-its-applications-in-otorhinolaryngology-head-and-neck-surgery
#5
Trevor D Crafts, Susan E Ellsperman, Todd J Wannemuehler, Travis D Bellicchi, Taha Z Shipchandler, Avinash V Mantravadi
Objective Three-dimensional (3D)-printing technology is being employed in a variety of medical and surgical specialties to improve patient care and advance resident physician training. As the costs of implementing 3D printing have declined, the use of this technology has expanded, especially within surgical specialties. This article explores the types of 3D printing available, highlights the benefits and drawbacks of each methodology, provides examples of how 3D printing has been applied within the field of otolaryngology-head and neck surgery, discusses future innovations, and explores the financial impact of these advances...
November 1, 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28418775/research-101-an-initiative-to-encourage-and-facilitate-quality-resident-research-in-a-military-setting
#6
Kathryn E Marshall, Tanisha L Hammill
Objective Describe and evaluate a structured research program initiated at a tertiary Department of Defense (DOD) Medical Training Facility (MTF) to encourage and facilitate the conduct of research investigations, specifically among residents and junior or inexperienced investigators, but applicable for all DOD otolaryngology (ENT) and audiology providers. Methods A new comprehensive program was deployed in the ENT clinic at Madigan Army Medical Center (MAMC) to help improve the research program. Identified gaps in research methods and regulatory training were incorporated into the existing graduate medical education program along with structured mentorship between residents and senior staff...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28418661/systematic-dissociation-pathway-searches-guided-by-principal-component-modes
#7
Zhiye Tang, Chia-En A Chang
We introduce a novel method, Pathway Search guided by Internal Motions (PSIM), that efficiently finds molecular dissociation pathways of a ligand-receptor system with guidance from principal component (PC) modes obtained from molecular dynamics (MD) simulations. Modeling ligand-receptor dissociation pathways can provide insights into molecular recognition and has practical applications, including understanding kinetic mechanisms and barriers to binding/unbinding as well as design of drugs with desired kinetic properties...
April 18, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28418270/usmle-and-otolaryngology-predicting-board-performance
#8
Liana Puscas, David Chang, Hui-Jie Lee, Rodney Diaz, Robert Miller
Objective To ascertain what relationship exists between the United States Medical Licensing Examination (USMLE) and the American Board of Otolaryngology Written Qualifying Examination (WQE). Study Design Retrospective, longitudinal study. Setting De-identified database. Subjects Residents entering otolaryngology-head and neck surgery (OHNS) residency between 2007 and 2009 and taking the WQE for the first time between 2012 and 2014. Methods Regression models were used to determine if the USMLE score predicts passage of the WQE on the first attempt, which step score was a better predictor, and whether an increase in the Step 2 score increased the chances of WQE passage...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28418112/photoresponsive-passive-micromixers-based-on-spiropyran-size-tunable-hydrogels
#9
Jeroen Ter Schiphorst, Giuseppe G Melpignano, Hossein Eslami Amirabadi, Menno H J M Houben, Sterre Bakker, Jaap M J den Toonder, Albertus P H J Schenning
Microfluidic devices allow the manipulation of fluids down to the micrometer scale and are receiving a lot of attention for applications where low volumes and high throughputs are required. In these micro channels, laminar flow usually dominates, which requires long residence times of the fluids, limiting the flow speed and throughput. Here a switchable passive mixer has been developed to control mixing and to easily clean microchannels. The mixer is based on a photoresponsive spiropyran based hydrogel of which the dimensions can be tuned by changing the intensity of the light...
April 18, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28414563/leveraging-stem-cell-homing-for-therapeutic-regeneration
#10
Y Yin, X Li, X T He, R X Wu, H H Sun, F M Chen
Resident stem cell pools in many tissues/organs are responsible not only for tissue maintenance during physiologic turnover but also for the process of wound repair following injury. With inspiration from stem cell trafficking within the body under physiologic and pathologic conditions, recent advances have been made toward inducing stem cell mobilization and directing patients' own cells to sites of interest for treating a broad spectrum of diseases. An evolving body of work corroborates that delivering guidance cues can mobilize stem cells from the bone marrow and drive these cells toward a specific region...
April 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28414045/viscosities-encountered-during-the-cryopreservation-of-dimethyl-sulphoxide-systems
#11
P Kilbride, G J Morris
This study determined the viscous conditions experienced by cells in the unfrozen freeze concentrated channels between ice crystals in slow cooling protocols. This was examined for both the binary Me2SO-water and the ternary Me2SO-NaCl-water systems. Viscosity increases from 6.9 ± 0.1 mPa s at -14.4 ± 0.3 °C to 958 ± 27 mPa s at -64.3 ± 0.4 °C in the binary system, and up to 55387 ± 1068 mPa s at -75 ± 0.5 °C in the ternary (10% Me2SO, 0.9% NaCl by weight) solution were seen. This increase in viscosity limits molecular diffusion, reducing adsorption onto the crystal plane...
April 14, 2017: Cryobiology
https://www.readbyqxmd.com/read/28413946/kinetics-of-ligand-binding-through-advanced-computational-approaches-a-review
#12
Alex Dickson, Pratyush Tiwary, Harish Vashisth
Ligand residence times and binding rates have been found to be useful quantities to consider during drug design. The underlying structural and dynamic determinants of these kinetic quantities are difficult to discern. Driven by developments in computational hardware and simulation methodologies, molecular dynamics (MD) studies of full binding and unbinding pathways have emerged recently, showing these structural and dynamic determinants in atomic detail. However, the long timescales related to drug binding and release are still prohibitive to conventional MD simulation...
April 14, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/28412786/-oral-and-maxillofacial-surgery-residency-training-in-the-united-states-what-can-we-learn
#13
Y F Ren
China is currently in the process of establishing formal residency training programs in oral and maxillofacial surgery and other medical and dental specialties. Regulatory agencies, and educational and academic institutions in China are exploring mechanisms, goals and standards of residency training that meet the needs of the Chinese healthcare system. This article provides an introduction of residency training in oral and maxillofacial surgery in the United States, with emphasis on the accreditation standard by the Commission on Dental Accreditation...
April 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28412566/removal-mechanisms-of-benzotriazoles-in-duckweed-lemna-minor-wastewater-treatment-systems
#14
Georgia Gatidou, Maria Oursouzidou, Aimilia Stefanatou, Athanasios S Stasinakis
The fate of five benzotriazoles (1H-benzotriazole, BTR; 4-methyl-1H-benzotriazole, 4TTR; 5-methyl-1H-benzotriazole, 5TTR; xylytriazole, XTR and 5-chlorobenzotriazole, CBTR) was studied in batch and continuous-flow Lemna minor systems and the role of different mechanisms on their removal was evaluated. Single and joint toxicity experiments were initially conducted using the Organization for Economic Co-operation and Development (OECD) protocol 221 and no inhibition on specific growth rate of Lemna minor was observed for concentrations up to 200μgL(-1)...
April 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28412446/development-and-characterization-of-mucoadhesive-buccal-gels-containing-lipid-nanoparticles-of-ibuprofen
#15
Ana Camila Marques, Ana Isabel Rocha, Paula Leal, Marilene Estanqueiro, José Manuel Sousa Lobo
The lipid nanoparticles, namely Nanostructured Lipid Carriers (NLC), as drug delivery systems have been investigated for several years. One of the delivery routes for which these carriers can be applied is buccal administration. However, the liquid dispersions of lipid nanoparticles can be rapidly removed from oral cavity by saliva. Thus, the development of a system that allows increased retention time on the mucosa is necessary. For this reason, the development of mucoadhesive preparations for buccal administration of lipid nanoparticles becomes important...
April 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28412167/mortality-in-nursing-homes-following-emergency-evacuation-a%C3%A2-systematic-review
#16
REVIEW
Melissa Willoughby, Chebiwot Kipsaina, Noha Ferrah, Soren Blau, Lyndal Bugeja, David Ranson, Joseph Elias Ibrahim
OBJECTIVES: To determine the risk associated with mortality among nursing home residents within 6 months following an evacuation because of man-made or natural disasters. DESIGN: A systematic review conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) Statement. SETTING: All peer-reviewed studies published in English, French, German, or Spanish between January 1, 2000 and December 31, 2015, examining mortality within 6 months of disaster evacuation from a nursing home...
April 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28412166/palliative-care-development-in-european-care-homes-and-nursing-homes-application-of-a-typology-of-implementation
#17
Katherine Froggatt, Sheila Payne, Hazel Morbey, Michaela Edwards, Harriet Finne-Soveri, Giovanni Gambassi, H Roeline Pasman, Katarzyna Szczerbińska, Lieve Van den Block
BACKGROUND: The provision of institutional long-term care for older people varies across Europe reflecting different models of health care delivery. Care for dying residents requires integration of palliative care into current care work, but little is known internationally of the different ways in which palliative care is being implemented in the care home setting. OBJECTIVES: To identify and classify, using a new typology, the variety of different strategic, operational, and organizational activities related to palliative care implementation in care homes across Europe...
April 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28411426/thoron-mitigation-system-based-on-charcoal-bed-for-applications-in-thorium-fuel-cycle-facilities-part-2-development-characterization-and-performance-evaluation
#18
K Sudeep Kumara, B K Sahoo, J J Gaware, B K Sapra, Y S Mayya, N Karunakara
Exposure due to thoron ((220)Rn) gas and its decay products in a thorium fuel cycle facility handling thorium or (232)U/(233)U mixture compounds is an important issue of radiological concern requiring control and mitigation. Adsorption in a flow-through charcoal bed offers an excellent method of alleviating the release of (220)Rn into occupational and public domain. In this paper, we present the design, development, and characterization of a Thoron Mitigation System (TMS) for industrial application. Systematic experiments were conducted in the TMS for examining the (220)Rn mitigation characteristics with respect to a host of parameters such as flow rate, pressure drop, charcoal grain size, charcoal mass and bed depth, water content, and heat of the carrier gas...
April 12, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28411332/evaluation-of-rosin-gum-and-eudragit%C3%A2-rs-po-as-a-functional-film-coating-material
#19
Suélen Plaza Pomin, Isabela Angeli de Lima, Rogério Ribeiro Pezarini, Osvaldo Albuquerque Cavalcanti
Polymers are essential tools in the research and development of new therapeutic devices. The diversity and flexibility of these materials have generated high expectations in the composition of new materials with extraordinary abilities, especially in the design of new systems for the modified release of pharmaceutically active ingredients. The natural polymer rosin features moisture protection and pH-dependent behavior (i.e., it is sensitive to pH > 7.0), suggesting its possible use in pharmaceutical systems...
April 14, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28410135/custom-built-tools-for-the-study-of-deer-antler-biology
#20
Wenhui Chu, Haiping Zhao, Junde Li, Chunyi Li
Deer antlers can be developed into multiple novel models to study growth and development of tissues for biomedical research. To facilitate this process, we have invented and further refined five custom-built tools through three decades of antler research. These are: 1. Pedicle growth detector to pinpoint the timing when pedicle growth is initiated, thus stimuli for pedicle and first antler formation can be investigated and identified. 2. Thin periosteum slice cutter to thinly slice (0.2mm or 0.7 mm thick) a whole piece of antlerogenic periosteum (AP) or pedicle periosteum (PP), which facilitates gene delivery into cells resident in these tissues, thus making transgenic antlers possible...
June 1, 2017: Frontiers in Bioscience (Landmark Edition)
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