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https://www.readbyqxmd.com/read/29161600/monitoring-wastewater-for-assessing-community-health-sewage-chemical-information-mining-scim
#1
Christian G Daughton
Timely assessment of the aggregate health of small-area human populations is essential for guiding the optimal investment of resources needed for preventing, avoiding, controlling, or mitigating human exposure risks, as well as for maintaining or promoting health. Seeking those interventions yielding the greatest benefit with respect to the allocation of resources is critical for making progress toward community sustainability, reducing health disparities, promoting social justice, and maintaining or improving collective health and well-being...
November 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29160858/hyperplanar-morphological-clustering-of-a-hippocampus-by-using-volumetric-computerized-tomography-in-early-alzheimer-s-disease
#2
Sarawut Suksuphew, Paramate Horkeaw
Background: On diagnosing Alzheimer's disease (AD), most existing imaging-based schemes have relied on analyzing the hippocampus and its peripheral structures. Recent studies have confirmed that volumetric variations are one of the primary indicators in differentiating symptomatic AD from healthy aging. In this study, we focused on deriving discriminative shape-based parameters that could effectively identify early AD from volumetric computerized tomography (VCT) delineation, which was previously almost intangible...
November 21, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29158832/clinical-translation-and-first-in-human-use-of-44-sc-sc-psma-617-for-pet-imaging-of-metastasized-castrate-resistant-prostate-cancer
#3
Elisabeth Eppard, Ana de la Fuente, Martina Benešová, Ambreen Khawar, Ralph A Bundschuh, Florian C Gärtner, Barbara Kreppel, Klaus Kopka, Markus Essler, Frank Rösch
BACKGROUND: Various trivalent radiometals are well suited for labeling of DOTA-conjugated variants of Glu-ureido-based prostate-specific membrane antigen (PSMA) inhibitors. The DOTA-conjugate PSMA-617 has proven high potential in PSMA radioligand therapy (PSMA-RLT) of prostate cancer as well as PET imaging when labeled with lutetium-177 and gallium-68 respectively. Considering the relatively short physical half-life of gallium-68 this positron emitter precludes prolonged acquisition periods, as required for pre-therapeutic dosimetry or intraoperative applications...
2017: Theranostics
https://www.readbyqxmd.com/read/29153729/ambient-air-pollution-and-the-risk-of%C3%A2-pregnancy-loss-a-prospective-cohort-study
#4
Sandie Ha, Rajeshwari Sundaram, Germaine M Buck Louis, Carrie Nobles, Indulaxmi Seeni, Seth Sherman, Pauline Mendola
OBJECTIVE: To estimate the association of pregnancy loss with common air pollutant exposure. Ambient air pollution exposure has been linked to adverse pregnancy outcomes, but few studies have investigated its relationship with pregnancy loss. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 343 singleton pregnancies in a multisite prospective cohort study with detailed protocols for ovulation and pregnancy testing...
November 14, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29152921/proximity-to-pediatric-cardiac-surgical-care-among-adolescents-with-congenital-heart-defects-in-11-new-york-counties
#5
Kristin M Sommerhalter, Tabassum Z Insaf, Tugba Akkaya-Hocagil, Claire E McGarry, Sherry L Farr, Karrie F Downing, George K Lui, Ali N Zaidi, Alissa R Van Zutphen
BACKGROUND: Many individuals with congenital heart defects (CHDs) discontinue cardiac care in adolescence, putting them at risk of adverse health outcomes. Because geographic barriers may contribute to cessation of care, we sought to characterize geographic access to comprehensive cardiac care among adolescents with CHDs. METHODS: Using a population-based, 11-county surveillance system of CHDs in New York, we characterized proximity to the nearest pediatric cardiac surgical care center among adolescents aged 11 to 19 years with CHDs...
November 1, 2017: Birth defects research
https://www.readbyqxmd.com/read/29151443/fasciola-hepatica-infection-in-water-buffalo-bubalus-bubalis-in-three-provinces-of-the-nile-delta-egypt-a-cross-sectional-study
#6
Abdelgawad Salah El-Tahawy, Nigel Kwan, Katsuaki Sugiura
A cross-sectional study was conducted to estimate the prevalence of Fasciola hepatica (F. hepatica) infection in water buffalo (Bubalus bubalis) in Alexandria, Beheira, and Kafr el-Sheikh governorates (provinces) of the Nile Delta in Egypt and to identify the underlying risk factors associated with the infection. A total of 29 farms (10 in Alexandria, 10 in Beheira, and 9 in Kafr el-Sheikh) were randomly selected and all the buffaloes that resided on these farms from 21 February 2015 to 20 February 2016 were included in the study...
November 20, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29150933/design-of-a-novel-continuous-flow-reactor-for-low-ph-viral-inactivation
#7
Stephanie A Parker, Linus Amarikwa, Kevin Vehar, Raquel Orozco, Scott Godfrey, Jon Coffman, Parviz Shamlou, Cameron L Bardliving
Insufficient mixing in laminar flow reactors due to diffusion-dominated flow limits their use in applications where narrow residence time distribution (RTD) is required. The aim of this study was to design and characterize a laminar flow (Re 187.7-375.5) tubular reactor for low pH viral inactivation with enhanced radial mixing via the incorporation of curvature and flow inversions. Towards this aim, the reactor described here, Jig in a Box (JIB), was designed with a flow path consisting of alternating 270° degree turns...
November 18, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29149651/anthropometric-measurements-in-iranian-men
#8
Jaber Gharehdaghi, Maryam Baazm, Masoud Ghadipasha, Sadra Solhi, Farhoud Toutounchian
There is inevitable need for data regarding anthropometric measurements of each community's population. These anthropometric data have various applications, including health assessment, industrial designing, plastic & orthopedic surgery, nutritional studies, anatomical studies and forensic medicine investigations. Anthropometric parameters vary from race to race throughout the world, hence providing an anthropometric profile model of residents of different geographic regions seems to be necessary. To our knowledge, there is no report of bone parameters of the Iranian population...
November 14, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29147467/problematic-communications-during-2016-fellowship-recruitment-in-internal-medicine
#9
Patricia A Cornett, Chris Williams, Richard L Alweis, John McConville, Michael Frank, Bhavin Dalal, Richard I Kopelman, Vera P Luther, Alec B O'connor, Elaine A Muchmore
Some internal medicine residency program directors have expressed concerns that their third-year residents may have been subjected to inappropriate communication during the 2016 fellowship recruitment season. The authors sought to study applicants' interpersonal communication experiences with fellowship programs. Many respondents indicated that they had been asked questions that would constitute violations of the National Residency Matching Program (NRMP) Communications Code of Conduct agreement, including how they plan to rank specific programs...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29146016/evaluating-the-performance-of-the-minute-feedback-system-a%C3%A2-web-based-feedback-tool-for-medical-students
#10
Patrick E Georgoff, Gabrielle Shaughness, Lisa Leininger, Vahagn C Nikolian, Gurjit Sandhu, Rishindra Reddy, David T Hughes
BACKGROUND: Medical students often report dissatisfaction with the feedback they receive on their clerkships. This study evaluates the performance of the Minute Feedback System (MFS), a web-based tool designed to facilitate medical student acquisition of same day written feedback from surgery residents and faculty. METHODS: System-generated data, targeted surveys, and end of clerkship questionnaires were used to evaluate MFS performance over a one-year period. RESULTS: 170 students made 3190 feedback requests and received 1978 responses (62% response rate)...
November 4, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29145313/the-importance-of-family-caregiving-to-achieving-palliative-care-at-home-a-case-report-of-end-of-life-breast-cancer-in-an-area-struck-by-the-2011-fukushima-nuclear-crisis-a-case-report
#11
Akihiko Ozaki, Masaharu Tsubokura, Claire Leppold, Toyoaki Sawano, Manabu Tsukada, Tsuyoshi Nemoto, Kazuhiro Kosugi, Yoshitaka Nishikawa, Shigeaki Kato, Hiromichi Ohira
RATIONALE: The primary setting of palliative care has shifted from inpatient care to patients' residences. Family caregiving is essential for patients with life-limiting illnesses to receive palliative care at home, however little information is available regarding potential interventions to achieve palliative homecare for those without sufficient support from family members in various settings, including disasters. PATIENT CONCERNS: In March 2011, Fukushima, Japan experienced an earthquake, tsunami and nuclear disaster...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144735/removal-of-pb-ii-ion-using-pamam-dendrimer-grafted-graphene-and-graphene-oxide-surfaces-a-molecular-dynamics-study
#12
Anitha Kommu, Vasumathi Velachi, M Natalia Dias Soeiro Cordeiro, Jayant Kumar Singh
The dendrimer polyamidoamine (PAMAM) has been widely applied in environmental applications as adsorbents for wastewater treatment. In this work, molecular dynamics simulations are conducted to understand the effect of dendrimer grafted graphene and graphene oxide on the structural and dynamical properties of Pb2+ ion. The adsorption capacity of the metal ion is improved significantly, over 60%, using carboxyl terminal groups of dendrimer molecule grafted on graphene oxide surface. We examine the self-diffusion coefficient and residence time of Pb2+ ion near graphene and graphene oxide surfaces grafted with PAMAM dendrimers using terminal groups, -COO- and -OH...
November 16, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29143997/epidermal-neural-crest-stem-cell-derived-glia-enhance-neurotrophic-elements-in-an-ex-vivo-model-of-spinal-cord-injury
#13
Sareh Pandamooz, Mohammad Saied Salehi, Mohammad Ismail Zibaii, Abolhassan Ahmadiani, Mohammad Nabiuni, Leila Dargahi
Growing evidence that cell-based therapies can improve recovery outcome in spinal cord injury (SCI) models substantiates their application for treatment of human with SCI. To address the effectiveness of these stem cells, potential candidates should be evaluated in proper SCI platform that allows direct real-time monitoring. In this study, the role of epidermal neural crest stem cells (EPI-NCSCs) was elucidated in an ex vivo model of SCI and valproic acid (VPA) was administered to ameliorate the inhospitable context of injury for grafted EPI-NCSCs...
November 16, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29143900/an-innovative-mobile-health-system-to-improve-and-standardize-antenatal-care-among-underserved-communities-a-feasibility-study-in-an-italian-hosting-center-for-asylum-seekers
#14
Lucia Borsari, Giovanna Stancanelli, Laura Guarenti, Teresa Grandi, Serena Leotta, Lucia Barcellini, Paola Borella, Anne Caroline Benski
Innovative migrant-friendly tools are needed to assist health personnel manage the high number of pregnancies within reception centers. This study tests functionality and acceptability of a new mHealth system in providing antenatal care amongst migrants. The study, carried out between 2014 and 2016, involved 150 pregnant women residing in the largest European migrant reception center in Sicily. A ticket tracking system assessed the system's functionality and a questionnaire assessed women's acceptability. The system facilitated the collection of clinical data, enabling the creation of electronic patient records and identifying 10% of pregnancies as high-risk...
November 16, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29140816/the-role-of-small-incision-suture-less-cataract-surgery-in-the-developed-world
#15
Sanduk Ruit, Reeta Gurung, Shyam Vyas
PURPOSE OF REVIEW: Manual small incision cataract surgery (MSICS) has recently gone through much refinement and fine tuning. It is often taken as an alternate option for phacoemulsification, especially in developing country. This review will present some insight on its applications especially for developed nations. The role of MSCIS in tackling complex cataracts with stony hard nucleus is fairly established. The role of training residents with MSCIS has certain advantages though debatable...
November 14, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29138622/antimicrobial-efficacy-of-penicillium-amestolkiae-elv609-extract-treated-cotton-fabric-for-diabetic-wound-care
#16
Nur Amiera Syuhada Binti Rozman, Nurhanis Syafiqah Binti Mohd Nor Hamin, Leong Chean Ring, Tan Wen Nee, Mahfuzah Binti Mustapha, Tong Woei Yenn
Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration and wound infection are major forms of disabilities arising from diabetic diseases. This study was aimed to develop a natural antimicrobial finishing on medical grade textile that meets American Association of Textiles Chemists and Colorists (AATCC) standard. The textile samples were finished with the ethanolic extract of Penicillium amestolkiae elv609, an endophytic fungus isolated from Orthosiphon stamineus Benth (common name: cat's whiskers)...
September 2017: Mycobiology
https://www.readbyqxmd.com/read/29137728/a-computational-model-for-false-lumen-thrombosis-in-type-b-aortic-dissection-following-thoracic-endovascular-repair
#17
Claudia Menichini, Zhuo Cheng, Richard G J Gibbs, Xiao Yun Xu
Thoracic endovascular repair (TEVAR) has recently been established as the preferred treatment option for complicated type B dissection. This procedure involves covering the primary entry tear to stimulate aortic remodelling and promote false lumen thrombosis thereby restoring true lumen flow. However, complications associated with incomplete false lumen thrombosis, such as aortic dilatation and stent graft induced new entry tears, can arise after TEVAR. This study presents the application and validation of a recently developed mathematical model for patient-specific prediction of thrombus formation and growth under physiologically realistic flow conditions...
November 11, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29136644/developmentally-regulated-internal-transcription-initiation-during-meiosis-in-budding-yeast
#18
Sai Zhou, Rolf Sternglanz, Aaron M Neiman
Sporulation of budding yeast is a developmental process in which cells undergo meiosis to generate stress-resistant progeny. The dynamic nature of the budding yeast meiotic transcriptome has been well established by a number of genome-wide studies. Here we develop an analysis pipeline to systematically identify novel transcription start sites that reside internal to a gene. Application of this pipeline to data from a synchronized meiotic time course reveals over 40 genes that display specific internal initiations in mid-sporulation...
2017: PloS One
https://www.readbyqxmd.com/read/29135781/defining-rurality-in-medicare-administrative-data
#19
John E Snyder, Matthew Jensen, Nguyen X Nguyen, Clara E Filice, Karen E Joynt
Rural beneficiaries make up nearly one quarter of the Medicare population, yet rural providers and patients face specific challenges with health and health care delivery that remain inadequately understood. Health disparities between rural and urban residents are widespread, barriers to health care in rural communities persist, and the rural health care workforce is limited. To better understand and track the relationship between rurality and performance under Medicare's payment programs, researchers must be able to identify rural beneficiaries, providers, and hospitals...
December 2017: Medical Care
https://www.readbyqxmd.com/read/29135675/novel-strategies-to-improve-resident-selection-by-improving-cultural-fit-aoa-critical-issues
#20
Scott E Porter, Afshin E Razi, T Bennett Ramsey
Residency selection is a perennial multifactorial process that differs considerably from the recruitment processes that other professional occupations enjoy. The 2016 meeting of the American Orthopaedic Association's Council of Orthopaedic Residency Directors highlighted a series of symposia that sought to present a novel manner of resident selection. Specifically, the presenters for each symposium were asked to do the following: present some general recruitment best practices in industries outside of medicine, present how branding of a program may translate into a better interview season, investigate evidence that the applicant pool to orthopaedic surgery may have changed and that residency program brands may have to reflect this, and assess our current evaluation techniques for talent identification and resident selection with respect to a specific department's appearance or brand...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
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