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https://www.readbyqxmd.com/read/29719353/meta-analysis-of-the-efficacy-and-safety-of-adjunctive-rosuvastatin-for-dyslipidemia-in-patients-with-schizophrenia
#1
Wei Zheng, Wei Yang, Qing-E Zhang, Xin-Hu Yang, Dong-Bin Cai, Jin-Qing Hu, Gabor S Ungvari, Chee H Ng, Marc De Hert, Yu-Ping Ning, Yu-Tao Xiang
Background: Metabolic syndrome in patients with schizophrenia is a major health concern. The efficacy and safety of adjunctive rosuvastatin in treating dyslipidemia were controversial. Aims: To assess the efficacy and safety of adjunctive rosuvastatin for dyslipidemia in patients with schizophrenia. Methods: We systematically searched for relevant controlled clinical trials from the following databases: PubMed, PsycINFO, Cochrane Library, China Knowledge Network, WanFang Database and Chinese Biomedical Database up to September 28, 2017...
February 25, 2018: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29719344/meta-analysis-of-the-efficacy-and-safety-of-repetitive-transcranial-magnetic-stimulation-rtms-in-the-treatment-of-depression
#2
REVIEW
Yanyan Wei, Junjuan Zhu, Shengke Pan, Hui Su, Hui Li, Jijun Wang
Background: Repetitive transcranial magnetic stimulation (rTMS) is a new type of physiotherapy technology that has been widely used in the research of depression. Although many clinical trials have found that compared to the placebo interventions, rTMS has a significant effect on the improvement of depressive symptoms, the outcomes remain inconsistent due to differences in rTMS treatment frequency, parameter settings, and site for stimulation. Aims: This study systematically evaluated the safety and efficacy of rTMS combined with antidepressants for the treatment of depression in Chinese and English randomized, double-blind and sham controlled trials and explored the possible related factors affecting the efficacy and safety...
December 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29718436/non-pharmacotherapeutic-interventions-in-travellers-diarrhoea-td
#3
Derek P Evans
Background: This is a review of some of the non-pharmacotherapeutic interventions in travellers diarrhoea (TD) looking particularly at the role of pre and probiotics, the evidence behind water purification and the impact of advice given and its adherence by travellers. Method: A systematic review of the research completed under section using the listed key words and searched using the databases of Google Scholar, Journal of Travel Medicine, QxMD, ReadCube and The Knowledge Network...
May 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29691122/emr-based-medical-knowledge-representation-and-inference-via-markov-random-fields-and-distributed-representation-learning
#4
Chao Zhao, Jingchi Jiang, Yi Guan, Xitong Guo, Bin He
OBJECTIVE: Electronic medical records (EMRs) contain medical knowledge that can be used for clinical decision support (CDS). Our objective is to develop a general system that can extract and represent knowledge contained in EMRs to support three CDS tasks-test recommendation, initial diagnosis, and treatment plan recommendation-given the condition of a patient. METHODS: We extracted four kinds of medical entities from records and constructed an EMR-based medical knowledge network (EMKN), in which nodes are entities and edges reflect their co-occurrence in a record...
April 22, 2018: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/29682132/creating-a-foundation-for-implementing-an-electronic-health-records-ehr-integrated-social-knowledge-networking-skn-system-on-medication-reconciliation
#5
P Rangachari, K C Dellsperger, D Fallaw, I Davis, M Sumner, W Ray, S Fiedler, T Nguyen, R Rethemeyer
Background: In fall 2016, Augusta University received a two-year grant from AHRQ, to implement a Social Knowledge Networking (SKN) system for enabling its health system, AU-Health, to progress from "limited use" of EHR Medication Reconciliation (MedRec) Technology, to "meaningful use." Phase 1 sought to identify a comprehensive set of issues related to EHR MedRec encountered by practitioners at AU-Health. These efforts helped develop a Reporting Tool , which, along with a Discussion Tool , was incorporated into the AU-Health EHR, at the end of Phase 1...
April 2018: Journal of Hospital Administration
https://www.readbyqxmd.com/read/29628673/the-case-based-learning-conference-model-at-emindia2017-a-novel-implementation-of-problem-based-educational-paradigm
#6
Vivek Chauhan, Sagar Galwankar, Stanislaw P Stawicki, Naman Agrawal, S Vimal Krishnan, Sanjeev Bhoi, Tej Prakash Sinha, Praveen Aggarwal
INDUSEM was established as an INDO-US Satellite Knowledge Network in 2005. It brought together the academic leaders and innovators from India and the US with the goal of creating collaborative synergies and creative solutions to advance the knowledge and science of emergency medicine (EM) in India. Since 2005, the leadership of INDUSEM devoted substantial resources, effort, and expertise to ensure that newly implemented clinical institutes and training programs have the necessary resources and logistical support to effectively advance EM and Traumatology Sciences in India...
January 2018: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29618941/implementing-a-social-knowledge-networking-skn-system-to-enable-meaningful-use-of-an-ehr-medication-reconciliation-system
#7
Pavani Rangachari
Background: Despite the regulatory impetus toward meaningful use of electronic health record (EHR) Medication Reconciliation (MedRec) to prevent medication errors during care transitions, hospital adherence has lagged for one chief reason: low physician engagement, stemming from lack of consensus about which physician is responsible for managing a patient's medication list. In October 2016, Augusta University received a 2-year grant from the Agency for Healthcare Research and Quality to implement a Social Knowledge Networking (SKN) system for enabling its health system (AU Health) to progress from "limited use" of EHR MedRec technology to "meaningful use...
2018: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/29610409/network-measures-of-collaborative-support-for-young-adults-with-autism
#8
Elizabeth McGhee Hassrick, Paul Shattuck, Kathleen Carley
OBJECTIVES: The treatment of autism requires complex, multimodal interventions, provided by parents and providers across settings. As young adults with autism spectrum disorder (ASD) transition into adulthood, new stakeholders are added to support planning for postsecondary employment. In this article, we investigate the use of dynamic social network measures that describe the resources of young adults throughout transition. METHODS: A longitudinal, dynamic social network survey (Social Dynamics of Intervention [SoDI]) was conceptualized, designed, and conducted as a feasibility test, measuring changes in collaboration among parents and school staff members who provided interventions for children with ASD in 2 urban public schools...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29544727/the-up-and-down-of-sleep-from-molecules-to-electrophysiology
#9
Irene Navarro-Lobato, Lisa Genzel
Alternations of up and down can be seen across many different levels during sleep. Neural firing-rates, synaptic markers, molecular pathways, and gene expression all show differential up and down regulation across brain areas and sleep stages. And also the hallmarks of sleep - sleep stage specific oscillations - are characterized themselves by up and down as seen within the slow oscillation or theta cycles. In this review, we summarize the up and down of sleep covering molecules to electrophysiology and present different theories how this up and down could be regulated by the up and down of sleep oscillations...
March 12, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29543667/improving-patient-safety-in-public-hospitals-developing-standard-measures-to-track-medical-errors-and-process-breakdowns
#10
Sara L Ackerman, Gato Gourley, Gem Le, Pamela Williams, Jinoos Yazdany, Urmimala Sarkar
OBJECTIVE: The aim of the study was to develop standards for tracking patient safety gaps in ambulatory care in safety net health systems. METHODS: Leaders from five California safety net health systems were invited to participate in a modified Delphi process sponsored by the Safety Promotion Action Research and Knowledge Network (SPARKNet) and the California Safety Net Institute in 2016. During each of the three Delphi rounds, the feasibility and validity of 13 proposed patient safety measures were discussed and prioritized...
March 14, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29536824/discriminate-the-response-of-acute-myeloid-leukemia-patients-to-treatment-by-using-proteomics-data-and-answer-set-programming
#11
Lokmane Chebouba, Bertrand Miannay, Dalila Boughaci, Carito Guziolowski
BACKGROUND: During the last years, several approaches were applied on biomedical data to detect disease specific proteins and genes in order to better target drugs. It was shown that statistical and machine learning based methods use mainly clinical data and improve later their results by adding omics data. This work proposes a new method to discriminate the response of Acute Myeloid Leukemia (AML) patients to treatment. The proposed approach uses proteomics data and prior regulatory knowledge in the form of networks to predict cancer treatment outcomes by finding out the different Boolean networks specific to each type of response to drugs...
March 8, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29530047/building-the-evidence-base-on-the-hiv-programme-in-india-an-integrated-approach-to-document-programmatic-learnings
#12
Deepika Ganju, Bidhubhusan Mahapatra, Rajatashuvra Adhikary, Sangram Kishor Patel, Niranjan Saggurti, Gina Dallabetta
BACKGROUND: The Knowledge Network project was launched in 2010 to build evidence on the HIV epidemic by using the data generated by HIV programme implementing organisations in India. This paper describes the implementation of the programme and the strategies adopted to enhance the capacity of individuals to document and publish HIV prevention programme learnings. Further, it discusses the outcomes of the initiative. METHODS: A multipronged approach was adopted, where a group of experts were brought together to collaborate with programme implementing organisations, review available data, develop research questions and guide peer-reviewed publications...
March 12, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29518242/exploring-anti-quorum-sensing-and-anti-virulence-based-strategies-to-fight-candida-albicans-infections-an-in-silico-approach
#13
Tânia Raquel Rodrigues Grainha, Paula Alexandra da Silva Jorge, Martín Pérez-Pérez, Gael Pérez Rodríguez, Maria Olívia Baptista Oliveira Pereira, Anália Maria Garcia Lourenço
The complex virulence attributes of Candida albicans are an attractive target to exploit in the development of new antifungals and anti-virulence strategies to combat C. albicans infections. Particularly, quorum sensing (QS) has been reported as critical for virulence regulation in C. albicans. This work presents two knowledge networks with up-to-date information about QS regulation and experimentally tested anti-QS and anti-virulence agents for C. albicans. A semi-automatic bioinformatics workflow that combines literature mining and expert curation was used to retrieve otherwise scattered information from the scientific literature...
May 1, 2018: FEMS Yeast Research
https://www.readbyqxmd.com/read/29486631/social-medicine-feminism-and-the-politics-of-population-from-transnational-knowledge-networks-to-national-social-movements-in-brazil-and-mexico
#14
Rafael de la Dehesa
This article examines the role of national actors articulated with an explicitly counter-hegemonic transnational knowledge network (TKN) mobilising around social medicine in policy debates on population control and family planning. It focuses primarily on Brazil, using Mexico as a shadow case to highlight salient points of contrast. In doing so, it makes two contributions to larger debates about TKNs. First, it highlights the plural and contested nature of the knowledge production they enact, underscoring contestation around a global reproductive regime that consolidated around family planning...
February 28, 2018: Global Public Health
https://www.readbyqxmd.com/read/29431577/what-does-diversity-mean-for-public-engagement-in-science-a-new-metric-for-innovation-ecosystem-diversity
#15
Vural Özdemir, Simon Springer
Diversity is increasingly at stake in early 21st century. Diversity is often conceptualized across ethnicity, gender, socioeconomic status, sexual preference, and professional credentials, among other categories of difference. These are important and relevant considerations and yet, they are incomplete. Diversity also rests in the way we frame questions long before answers are sought. Such diversity in the framing (epistemology) of scientific and societal questions is important for they influence the types of data, results, and impacts produced by research...
March 2018: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29428070/max-margin-weight-learning-for-medical-knowledge-network
#16
Jingchi Jiang, Jing Xie, Chao Zhao, Jia Su, Yi Guan, Qiubin Yu
BACKGROUND AND OBJECTIVE: The application of medical knowledge strongly affects the performance of intelligent diagnosis, and method of learning the weights of medical knowledge plays a substantial role in probabilistic graphical models (PGMs). The purpose of this study is to investigate a discriminative weight-learning method based on a medical knowledge network (MKN). METHODS: We propose a training model called the maximum margin medical knowledge network (M3 KN), which is strictly derived for calculating the weight of medical knowledge...
March 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29346908/mechanisms-of-self-organized-criticality-in-social-processes-of-knowledge-creation
#17
Bosiljka Tadić, Marija Mitrović Dankulov, Roderick Melnik
In online social dynamics, a robust scale invariance appears as a key feature of collaborative efforts that lead to new social value. The underlying empirical data thus offers a unique opportunity to study the origin of self-organized criticality (SOC) in social systems. In contrast to physical systems in the laboratory, various human attributes of the actors play an essential role in the process along with the contents (cognitive, emotional) of the communicated artifacts. As a prototypical example, we consider the social endeavor of knowledge creation via Questions and Answers (Q&A)...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29343412/implementing-genome-driven-personalized-cardiology-in-clinical-practice
#18
REVIEW
Ares Pasipoularides
Genomics designates the coordinated investigation of a large number of genes in the context of a biological process or disease. It may be long before we attain comprehensive understanding of the genomics of common complex cardiovascular diseases (CVDs) such as inherited cardiomyopathies, valvular diseases, primary arrhythmogenic conditions, congenital heart syndromes, hypercholesterolemia and atherosclerotic heart disease, hypertensive syndromes, and heart failure with preserved/reduced ejection fraction. Nonetheless, as genomics is evolving rapidly, it is constructive to survey now pertinent concepts and breakthroughs...
January 16, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29279656/prevalence-and-major-causes-of-visual-impairment-in-iranian-adults-a-systematic-review
#19
REVIEW
Seyed-Farzad Mohammadi, Ghasem Saeedi-Anari, Elham Ashrafi, Seyed-Mehrdad Mohammadi, Farshad Farzadfar, Alireza Lashay, Hassan Hashemi
PURPOSE: The purpose of this study is to provide a pooled estimate of moderate-to-severe visual impairment (MSVI) and blindness in Iran for people 50 years and over and to identify the major causes through systematic review. MATERIALS AND METHODS: International (PubMed, ISI Web of Science, and Scopus) and national databases (Scientific Information Database, Barakat Knowledge Network System, Iran Databank of Ophthalmology Research, and Magiran) databases were searched...
July 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29189491/project-echo-a-telementoring-network-model-for-continuing-professional-development
#20
Sanjeev Arora, Summers G Kalishman, Karla A Thornton, Miriam S Komaromy, Joanna G Katzman, Bruce B Struminger, William F Rayburn
INTRODUCTION: A major challenge with current systems of CME is the inability to translate the explosive growth in health care knowledge into daily practice. Project ECHO (Extension for Community Healthcare Outcomes) is a telementoring network designed for continuing professional development (CPD) and improving patient outcomes. The purpose of this article was to describe how the model has complied with recommendations from several authoritative reports about redesigning and enhancing CPD...
October 2017: Journal of Continuing Education in the Health Professions
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