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systemic lupus erithematosus and pregnancy

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https://www.readbyqxmd.com/read/21794784/-pathogenic-mechanisms-of-the-anti-phospholipid-antibodies
#1
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Carlos A Núñez-Álvarez, Javier Cabiedes
The antiphospolipid syndrome (APS) is an autoimmune disease characterized by recurrent fetal loss, thrombotic events (arterial or venous) and hemocytopenic disorders associated to high titers of circulating aPL. Two variants of the APS have been described. Primary APS is a clinical entity without evidence of any other autoimmune disease and secondary APS is a clinical disorder mainly associated with Systemic Lupus Erithematosus (SLE). aPL are a widely group of immunoglobulins directed against different components or proteins factors...
January 2011: Reumatología Clinica
https://www.readbyqxmd.com/read/19820672/-pregnancy-and-antiphospholipid-antibodies-in-systemic-lupus-erithematosus-patients-an-outcome-evaluation
#2
Alexandra Cordeiro, Rita Lermann, Paula Ambrósio, Isabel Nogueira, Fátima Serrano
BACKGROUND AND AIMS: Antiphospholipid antibodies (APLAs) have been associated with pregnancy loss and other obstetric complications, such as pre--eclampsia, fetal growth restriction and preterm delivery. Systemic lupus erythematosus (SLE) patients frequently present APLAs and secondary antiphospholipid syndrome. The purpose of this work is to evaluate pregnancy outcome in SLE patients with and without APLAs. MATERIAL AND METHODS: Retrospective analysis of 136 gestations in women with SLE diagnosis previous to pregnancy that underwent surveillance in our maternity from 1993 to 2007...
July 2009: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/16972729/-hyperhomocystinemia-as-a-thrombotic-risk-factor-in-patients-suffering-from-systemic-lupus-erithematosus-and-antiphospholipid-syndrome
#3
Laura Onetti, Susana Villafañe, Emilia Menso, Cristina Drenkard, Susana Gamron, Gloria Barberis, Carlos M Onetti
OBJECTIVES: to detect the prevalence of hyperhcy in SLE patients with and without antiphospholipid syndrom; to compare the Hcy levels between those patients and healthy controls and to determine the correlation between hyperhcy and antiphospholipid antibodies. PATIENTS AND METHODS: we studied 44 SLE patients: 17 had antiphospholipid syndrom and 27 didn't have it, and we compared them to 24 healthy controls. All of them where checked clinically and with laboratory tests like anticardiolypin antibodies, lupus anticoagulant and Hcy...
2005: Revista de la Facultad de Ciencias Médicas
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