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https://www.readbyqxmd.com/read/27270883/validation-of-a-prediction-model-for-post-discharge-nausea-and-vomiting-after-general-anaesthesia-in-a-cohort-of-swedish-ambulatory-surgery-patients
#1
Jakob Walldén, Jesper Flodin, Magnus Hultin
BACKGROUND: In ambulatory surgery, post-discharge nausea and vomiting (PDNV) has been identified as a significant problem occurring in more than one-third of patients. OBJECTIVE: To validate a simplified PDNV score in a Swedish population. DESIGN: Prospective observational study. SETTING: Two county hospitals in Sweden: Sundsvall from June 2012 to May 2013 and Sunderbyn from January to October 2014. PATIENTS: Adult patients undergoing ambulatory surgery under general anaesthesia...
October 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26408510/ponv-pdnv-why-is-it-still-the-big%C3%A2-little%C3%A2-problem
#2
EDITORIAL
Vallire D Hooper
No abstract text is available yet for this article.
October 2015: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/25900234/postdischarge-nausea-and-vomiting-remains-frequent-after-le-fort-i-osteotomy-despite-implementation-of-a-multimodal-antiemetic-protocol-effective-in-reducing-postoperative-nausea-and-vomiting
#3
COMPARATIVE STUDY
Carolyn Dicus Brookes, Timothy A Turvey, Ceib Phillips, Vincent Kopp, Jay A Anderson
PURPOSE: To assess the prevalence of postdischarge nausea and vomiting (PDNV) after Le Fort I osteotomy with and without the use of a multimodal antiemetic protocol shown to decrease postoperative nausea and vomiting (PONV). MATERIALS AND METHODS: Consecutive patients undergoing Le Fort I osteotomy with or without additional procedures at a single academic institution formed the intervention cohort for an institutional review board-approved prospective clinical trial with a retrospective comparison group...
July 2015: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/25135275/-general-anesthesia-for-ambulatory-surgery-clinical-pharmacological-considerations-on-the-practical-approach
#4
REVIEW
S Löser, A Herminghaus, T Hüppe, W Wilhelm
Due to modern surgical and anesthesia techniques, many patients undergoing small or even medium surgical procedures will recover within minutes and can then be discharged after a few hours of monitoring. Aside from an optimized surgical technique, a precise and differentiated anesthesia concept is needed to guarantee rapid recovery and home readiness. Nowadays, remifentanil-propofol represents the standard regime in ambulatory anesthesia. The use of alfentanil, desfluran or sevofluran is also possible whereas other intravenous or inhaled anesthetics or other opioids are rarely used...
November 2014: Der Anaesthesist
https://www.readbyqxmd.com/read/25062571/postdischarge-nausea-and-vomiting-management-strategies-and-outcomes-over-7-days
#5
Jan Odom-Forren, Vallire Hooper, Debra K Moser, Lynne A Hall, Terry A Lennie, Joseph Holtman, Melissa Thomas, Zohn Centimole, Carrell Rush, Christian C Apfel
PURPOSE: The purpose of this study is to determine patient management strategies and outcomes for self-care of postdischarge nausea and vomiting (PDNV). DESIGN: Prospective, comparative, descriptive, and longitudinal study. METHODS: The sample consisted of 248 patients aged 18 years or older undergoing a procedure requiring general anesthesia. Patients recorded incidence and severity of nausea and vomiting, the impact of symptoms, and actions taken to alleviate symptoms for 7 days postdischarge...
August 2014: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/24882134/long-acting-serotonin-antagonist-palonosetron-and-the-nk-1-receptor-antagonists-does-extended-duration-of-action-improve-efficacy
#6
REVIEW
M Stephen Melton, Karen C Nielsen, Marcy Tucker, Stephen M Klein, Tong J Gan
In a growing outpatient surgical population, postdischarge nausea and vomiting (PDNV) is unfortunately a common and costly anesthetic complication. Identification of risk factors for both postoperative nausea and vomiting and PDNV is the hallmark of prevention and management. New pharmacologic interventions with extended duration of action, including palonosetron and aprepritant, may prove to be more efficacious.
June 2014: Anesthesiology Clinics
https://www.readbyqxmd.com/read/24578078/association-between-serotonin-transport-polymorphisms-and-postdischarge-nausea-and-vomiting-in-women-following-breast-cancer-surgery
#7
Susan W Wesmiller, Catherine M Bender, Susan M Sereika, Gretchen Ahrendt, Marguerite Bonaventura, Dana H Bovbjerg, Yvette Conley
PURPOSE/OBJECTIVES: To examine the association of the serotonin transport gene and postdischarge nausea and vomiting (PDNV) in women following breast cancer surgery. DESIGN: A cross-sectional study. SETTING: A comprehensive cancer center in Pittsburgh, PA. SAMPLE: 80 post-menopausal women treated surgically for early-stage breast cancer. METHODS: Data were collected using standardized instruments after surgery but before the initiation of chemotherapy...
March 1, 2014: Oncology Nursing Forum
https://www.readbyqxmd.com/read/24495419/pathophysiological-and-neurochemical-mechanisms-of-postoperative-nausea-and-vomiting
#8
REVIEW
Charles C Horn, William J Wallisch, Gregg E Homanics, John P Williams
Clinical research shows that postoperative nausea and vomiting (PONV) is caused primarily by the use of inhalational anesthesia and opioid analgesics. PONV is also increased by several risk predictors, including a young age, female sex, lack of smoking, and a history of motion sickness. Genetic studies are beginning to shed light on the variability in patient experiences of PONV by assessing polymorphisms of gene targets known to play roles in emesis (serotonin type 3, 5-HT3; opioid; muscarinic; and dopamine type 2, D2, receptors) and the metabolism of antiemetic drugs (e...
January 5, 2014: European Journal of Pharmacology
https://www.readbyqxmd.com/read/23988801/incidence-and-predictors-of-postdischarge-nausea-and-vomiting-in-a-7-day-population
#9
MULTICENTER STUDY
Jan Odom-Forren, Leena Jalota, Debra K Moser, Terry A Lennie, Lynne A Hall, Joseph Holtman, Vallire Hooper, Christian C Apfel
STUDY OBJECTIVE: 1) To quantify the incidence and severity of postdischarge nausea and vomiting (PDNV) for 7 days in adults undergoing outpatient surgeries with general anesthesia; 2) to evaluate whether a risk model previously developed for the first two postoperative days may be used to predict the patient's risk of PDNV for 7 days; and 3) to verify whether the same risk factors are applicable in the 3 to 7 day period. DESIGN: Prospective study. SETTING: Two university-affiliated centers...
November 2013: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/23313231/review-and-recommendations-for-the-prevention-management-and-treatment-of-postoperative-and-postdischarge-nausea-and-vomiting
#10
REVIEW
Danielle Cruthirds, Pamela J Sims, Patrick J Louis
Patients have rated severe nausea to be worse than postoperative pain. The overall incidence of postoperative nausea and vomiting (PONV) is 25%-30% and can lead to delayed discharge and unanticipated hospital admission. After outpatient surgery, the overall incidence of postdischarge nausea has been reported to be 17% and of vomiting 8%, higher than nausea and vomiting reported during the procedure or recovery. Patients who experienced postdischarge nausea and vomiting (PDNV) were unable to resume normal daily activities as quickly...
May 2013: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/23075768/nausea-and-vomiting-after-surgery-it-is-not-just-postoperative
#11
REVIEW
J Lance Lichtor
PURPOSE OF REVIEW: The purpose of this review is to highlight postoperative nausea and vomiting (PONV), to discuss why it occurs, how it might be prevented and then how it can be treated. RECENT FINDINGS: PONV/postdischarge nausea and vomiting (PDNV) is a problem that patients identify as one of the worst, if not the worst problem that can occur after surgery. Therapy is not perfect, yet there are anaesthesia techniques that can help minimize the problem and drugs that can be used both to prevent and also treat the problem once it occurs...
December 2012: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/22846680/who-is-at-risk-for-postdischarge-nausea-and-vomiting-after-ambulatory-surgery
#12
Christian C Apfel, Beverly K Philip, Ozlem S Cakmakkaya, Ashley Shilling, Yun-Ying Shi, John B Leslie, Martin Allard, Alparslan Turan, Pamela Windle, Jan Odom-Forren, Vallire D Hooper, Oliver C Radke, Joseph Ruiz, Anthony Kovac
BACKGROUND: About one in four patients suffers from postoperative nausea and vomiting. Fortunately, risk scores have been developed to better manage this outcome in hospitalized patients, but there is currently no risk score for postdischarge nausea and vomiting (PDNV) in ambulatory surgical patients. METHODS: We conducted a prospective multicenter study of 2,170 adults undergoing general anesthesia at ambulatory surgery centers in the United States from 2007 to 2008...
September 2012: Anesthesiology
https://www.readbyqxmd.com/read/22223185/a-time-motion-economic-analysis-of-postoperative-nausea-and-vomiting-in-ambulatory-surgery
#13
Ivan Parra-Sanchez, Rania Abdallah, Jing You, Alex Z Fu, Martin Grady, Kenneth Cummings, Christian Apfel, Daniel I Sessler
BACKGROUND: One-third of surgical outpatients experience postoperative nausea and vomiting (PONV) during their hospital stay or post-discharge nausea and vomiting (PDNV) after hospitalization. We determined the incremental costs of PONV/PDNV in ambulatory patients with this time-and-motion study. METHODS: In 100 ambulatory surgery patients, we evaluated the incidence of PONV, time staff spent with patients, use of PONV-related supplies, recovery duration, PONV rescue treatments, and quality-of-life through to the third postoperative morning...
April 2012: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/21934496/management-of-postdischarge-nausea-and-vomiting-after-ambulatory-surgery
#14
REVIEW
M Stephen Melton, Stephen M Klein, Tong J Gan
PURPOSE OF REVIEW: Although there are extensive studies of postoperative and postdischarge nausea and vomiting (PONV/PDNV) up to 24  h, few investigate 'delayed PDNV'. With an increasing outpatient surgical population, specific 'delayed PDNV' risk identification and management is necessary for improving outcomes and helping patients after discharge. This review will discuss possible PDNV specific risk factors, successful prevention and management of PDNV following ambulatory anesthesia and the principles and pharmacology of these interventions...
December 2011: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/21519222/a-randomized-double-blind-study-to-evaluate-efficacy-of-palonosetron-with-dexamethasone-versus-palonosetron-alone-for-prevention-of-postoperative-and-postdischarge-nausea-and-vomiting-in-subjects-undergoing-laparoscopic-surgeries-with-high-emetogenic-risk
#15
RANDOMIZED CONTROLLED TRIAL
Jeanna D Blitz, Michael Haile, Richard Kline, Lola Franco, Sorosch Didehvar, H Leon Pachter, Elliot Newman, Alex Bekker
Postoperative nausea and vomiting (PONV) and postdischarge nausea and vomiting (PDNV) are common occurrences (50%-80%) after laparoscopic surgery. Palonosetron (Pal), the newest 5-HT3 antagonist, is an effective antiemetic that has advantages in treating PDNV due to its prolonged duration of action. We hypothesized that a combination of Pal and dexamethazone (Dex) could further improve the efficacy of the treatment in comparison to Pal alone in patients at high risk for PONV. Patients scheduled to undergo laparoscopic surgeries under general anesthesia were randomized to receive 8-mg dexamethasone + 0...
September 2012: American Journal of Therapeutics
https://www.readbyqxmd.com/read/20871394/neurokinin-1-and-novel-serotonin-antagonists-for-postoperative-and-postdischarge-nausea-and-vomiting
#16
REVIEW
Elizabeth George, Cyrill Hornuss, Christian C Apfel
PURPOSE OF REVIEW: This review will address novel options for the prevention and treatment of postoperative and postdischarge nausea and vomiting (PONV and PDNV) after ambulatory anesthesia. In particular, this paper will review the characteristics of neurokinin-1 receptor antagonists (NK1-RAs) and the new serotonin receptor antagonist (5HT3-RA) palonosetron. Finally, we will discuss strategies for prophylaxis and treatment of PONV and PDNV that address the unique concerns in ambulatory surgery patients...
December 2010: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/20488392/update-on-the-management-of-postoperative-nausea-and-vomiting-and-postdischarge-nausea-and-vomiting-in-ambulatory-surgery
#17
REVIEW
Tina P Le, Tong Joo Gan
Postoperative nausea and vomiting (PONV) continues to be one of the most common complaints following surgery, occurring in more than 30% of surgeries, or as high as 70% to 80% in certain high-risk populations without prophylaxis. The 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonists continue to be the mainstay of antiemetic therapy, but newer approaches, such as neurokinin-1 antagonists, a longer-acting serotonin receptor antagonist, multimodal management, and novel techniques for managing high-risk patients are gaining prominence...
June 2010: Anesthesiology Clinics
https://www.readbyqxmd.com/read/19730966/double-blind-comparison-of-granisetron-promethazine-or-a-combination-of-both-for-the-prevention-of-postoperative-nausea-and-vomiting-in-females-undergoing-outpatient-laparoscopies
#18
RANDOMIZED CONTROLLED TRIAL
Tong J Gan, Keith A Candiotti, Stephen M Klein, Yiliam Rodriguez, Karen C Nielsen, William D White, Ashraf S Habib
PURPOSE: Postoperative nausea and vomiting (PONV) and postdischarge nausea and vomiting (PDNV) are common problems after surgery. Prophylactic combination antiemetic therapy is recommended for patients at high risk for developing PONV and PDNV. Granisetron, a serotonin antagonist, is an effective antiemetic that is devoid of sedative side effect. Although promethazine is effective, commonly used doses are associated with sedation. This study investigates the combination of low doses of granisetron and promethazine for the prevention of PONV...
November 2009: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/19512914/nausea-and-vomiting-after-office-based-anesthesia
#19
REVIEW
Kerstin Kolodzie, Christian C Apfel
PURPOSE OF THE REVIEW: Safety, quality, and patient satisfaction are not only defined by the incidences of serious adverse events but also include postoperative outcomes such as postdischarge nausea and vomiting (PDNV). PDNV has a high impact on patient recovery and may influence the cost-effectiveness of office-based surgical procedures. This article reviews the incidences and risk factors for PDNV as well as medications and concepts for prophylaxis and treatment. RECENT FINDINGS: Patients with PDNV require a longer recovery time to resume normal activities...
August 2009: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/19412558/aprepitant-in-a-multimodal-approach-for-prevention-of-postoperative-nausea-and-vomiting-in-high-risk-patients-is-there-such-a-thing-as-too-many-modalities
#20
John J Hache, Manuel C Vallejo, Jonathan H Waters, Brian A Williams
Postoperative and postdischarge nausea and vomiting (PONV and PDNV, respectively) add morbidity to perioperative outcomes. Combining some antiemetic agents of different mechanisms is more effective than using single agents, although this concept has not yet been tested extensively with aprepitant. Consecutive high-risk patients for PONV (n = 100) were given preoperative aprepitant 40 mg before surgery and were followed perioperatively. Female patients receiving general anesthesia (n = 81) were selected for data analysis...
2009: TheScientificWorldJournal
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