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Churg Strauss Syndrome

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https://www.readbyqxmd.com/read/27910080/churg-strauss-syndrome-with-endocardial-injury-clot-formation-in-heart-s-chambers-and-neurological-complications
#1
Robert Bujak, Jan Błażejewski, Joanna Banach, Danuta Karasek, Władysław Sinkiewicz
No abstract text is available yet for this article.
2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27893661/acute-coronary-vasospasm-in-a-patient-with-eosinophilic-granulomatosis-with-polyangiitis-following-nsaid-administration-a-case-report
#2
Naïl Benallegue, Pierre Lozach, Cristina Belizna, Christian Lavigne, Geoffrey Urbanski
Eosinophilic with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome) is a rare systemic disease characterized by a small-vessel necrotizing vasculitis. Cardiac manifestations are broad-ranging and are associated with a poor prognosis. Coronary vasospasm is uncommon.Here, we report a case of an acute coronary vasospasm in a patient with EGPA after corticosteroids withdrawal and nonsteroidal antiinflammatory drug (NSAID) introduction. This patient was initially misdiagnosed as bradykinin-mediated angioedema...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27857032/eosinophilic-granulomatosis-with-polyangiitis-presenting-with-skin-rashes-eosinophilic-cholecystitis-and-retinal-vasculitis
#3
Mingbing Zeng, Xialin Liu, Yizhi Liu
BACKGROUND Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome (CSS), is a rare vasculitis of unknown etiology. Most of the patients have a long history of asthma and then develop autoimmune inflammation of small and medium-sized blood vessels, with consequent reduction of blood flow to various organs and tissues. EGPA can cause disorders in multiple systems; the most seriously affected organs are the retina, kidney, brain, cardiovascular system, and skin. CASE REPORT The patient was hospitalized for high fever and skin rashes and then developed right upper abdominal pain, decreased visual acuity, coma, and convulsions...
November 18, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27846662/-the-lymphoid-variant-of-hes-l-hes-as-differential-diagnose-of-severe-asthma-in-childhood
#4
T Leu, S Rauthe, C Wirth, H-U Simon, V Kunzmann, H Hebestreit, S Kunzmann
Based on a case report an overview on the differential diagnostic considerations with respect to blood hypereosinophilia (HE) and hypereosinophilic syndromes (HES) in childhood is given. A 13-year-old boy was admitted for the clarification of an asthma. In the blood count an increased HE with 3 500/µl (30%) was found along with elevated total serum IgE and IL-5 level (2 000 IU/ml and 17 pg/ml). Lung function showed an obstruction (FEV1 38%). Radiologically the picture of bronchiectasis and mucus pluggine appeared...
November 2016: Klinische Pädiatrie
https://www.readbyqxmd.com/read/27826352/native-t1-mapping-demonstrating-apical-thrombi-in-eosinophilic-myocarditis-associated-with-churg-strauss-syndrome
#5
Kyongmin Sarah Beck, Soh Yong Jeong, Kyo Young Lee, Kiyuk Chang, Jung Im Jung
Eosinophilic myocarditis is a disease characterized by eosinophilic infiltration of the myocardium, consisting of acute necrotic stage, thrombotic stage, and fibrotic stage. Although T1 mapping has been increasingly used in various cardiac pathologies, there has been no report of T1 mapping in eosinophilic myocarditis. We report a case of 75-year-old female with eosinophilic myocarditis, whose cardiac magnetic resonance imaging included native T1 mapping, in which apical thrombi were distinctly seen as areas with decreased T1 values, next to areas of inflammation seen as increased T1 value in subendocardium...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27825424/radiological-and-clinical-features-of-eosinophilic-granulomatosis-with-polyangiitis
#6
Xiao-Li Xu, Wei Song, Xin Sui, Lan Song, Qian-Ni DU, Xiao Wang
Eosinophilic granulomatosis with polyangiitis(EGPA),also known as Churg-Strauss syndrome,is a clinically rare small-vessel vasculitis associated with antineutrophil cytoplasmic antibodies (ANCAs) and the hypereosinophilic syndromes (HESs),characterized by asthma,disseminated necrotizing vasculitis,extravascular granulomas,peripheral eosinophilia,and tissue eosinophilia. This article reviews the pathology,imaging,and clinical features of EGPA.
October 10, 2016: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/27798419/novel-targets-of-omalizumab-in-asthma
#7
Caroline Sattler, Gilles Garcia, Marc Humbert
PURPOSE OF REVIEW: Omalizumab is a recombinant humanized anti-IgE monoclonal antibody approved in the US for moderate to severe persistent allergic asthma (severe persistent asthma in the European Union), uncontrolled despite treatment with inhaled corticosteroids and long-acting beta2 agonists. It reduces asthma exacerbations, symptoms, oral corticosteroid doses, and improves quality of life. RECENT FINDINGS: Omalizumab may have an antiviral effect when used as a preventive therapy for fall exacerbations in children and teenagers...
January 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27759482/dermatologic-uses-of-omalizumab
#8
Justin C Chia, P Régine Mydlarski
PURPOSE: Omalizumab is a recombinant humanized monoclonal antibody that inhibits the binding of immunoglobulin E (IgE) to the high-affinity IgE receptor (FceRI) on the surface of mast cells and basophils. Omalizumab has been approved for use in asthma, and new reports show promise in a variety of dermatologic diseases. Herein, we review the literature on omalizumab in dermatology and discuss the safety, efficacy and mechanisms of action for this emerging therapy. MATERIALS AND METHODS: PubMED, MEDLINE and Embase databases were searched for the period 1 January 1990 to 1 September 2016...
November 7, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27733943/updates-in-anca-associated-vasculitis
#9
Christian Pagnoux
Antineutrophil cytoplasm antibody (ANCA)-associated vasculitides are small-vessel vasculitides that include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). Renal-limited ANCA-associated vasculitides can be considered the fourth entity. Despite their rarity and still unknown cause(s), research pertaining to ANCA-associated vasculitides has been very active over the past decades. The pathogenic role of antimyeloperoxidase ANCA (MPO-ANCA) has been supported using several animal models, but that of antiproteinase 3 ANCA (PR3-ANCA) has not been as strongly demonstrated...
September 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27728665/churg-strauss-syndrome-formes-frustes-a-case-report
#10
A Singh, P Jain, A Sharma, M Ali, V Arya
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27725542/echocardiographic-changes-in-eosinophilic-endocarditis-induced-by-churg-strauss-syndrome
#11
Nobuyuki Masaki, Ami Issiki, Masato Kirimura, Tetsuo Kamiyama, Osamu Sasaki, Hiroyuki Ito, Yoshiaki Maruyama, Toshihiko Nishioka
Eosinophilic myocarditis may be accompanied by Churg-Strauss syndrome (CSS). We report a case of CSS that was accompanied by myocardial changes in the early stage. A 71-year-old woman complained of mild chest pain at rest, but routine echocardiography did not reveal any endocardial abnormalities. Four months later, the patient was hospitalized due to congestive heart failure with neuropathy of both upper extremities. A diagnosis of eosinophilic myocarditis was made based on the patient's laboratory results and the presence of mural thrombus...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27625985/think-twice-diagnostic-delay-in-a-patient-with-acute-chest-pain
#12
Cæcilie Larsen Bang, Celeste Michala Porsbjerg
Heart involvement is the most critical and potentially lethal systemic manifestation in eosinophilic granulomatosis with polyangiitis (EGPA). We present a case of acute chest pain in a 58-year-old male with severe asthma, which regressed after sublingual administration of nitroglycerine. At the time of hospital admission, there were non-specific ST-changes on the ecg, coronary enzymes were increased, and the patient was concluded to have a non-ST-elevation myocardial infarction, and treated as such. A subacute cardiac catheterization showed no signs of significant coronary stenosis...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27549670/a-diagnostic-algorithm-for-eosinophilic-granulomatosis-with-polyangiitis-initially-diagnosed-as-lumbar-disc-hernia-or-lumbar-spinal-stenosis-personal-experience-and-review-of-the-literature
#13
Kosei Nagata, Shinichi Yamamoto, Kota Miyoshi, Masaki Sato, Yusuke Arino, Yoji Mikami
Eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss syndrome) is a rare systemic vasculitis and is difficult to diagnose. EGPA has a number of symptoms including peripheral dysesthesia caused by mononeuropathy multiplex, which is similar to radiculopathy due to lumbar disc hernia or lumbar spinal stenosis. Therefore, EGPA patients with mononeuropathy multiplex often visit orthopedic clinics, but orthopedic doctors and spine neurosurgeons have limited experience in diagnosing EGPA because of its rarity...
August 2016: Acta Medica Okayama
https://www.readbyqxmd.com/read/27480561/-misdiagnosed-as-hemorrhagic-infarction-in-anti-neutrophil-cytoplasmic-antibodies-negative-churg-strauss-syndrome-with-reactive-vasculitis-a-case-report
#14
X F Wang, D Y Xia, X Huang
No abstract text is available yet for this article.
August 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/27431867/not-all-coughs-are-asthma-or-allergies-churg-strauss-syndrome
#15
Ani A Bodoutchian, Hitender Jain, Tania Velez
BACKGROUND: Cardiomyopathy in patients with Churg-Strauss syndrome (CSS) carries a poor prognosis, with a high 5-year mortality rate, and requires treatment with immunosuppressive therapy. There is no single pathognomonic test or clinical finding for diagnosing CSS; instead, it is based upon meeting four of six criteria. CASE REPORT: A 47-year-old woman with a 6-month medical history of "asthma" presented to our hospital with a 1-month history or dyspnea on exertion...
September 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27381148/churg-strauss-syndrome-in-a-pediatric-patient-presenting-with-recurrent-hemorrhagic-stroke-and-mitral-regurgitation-due-to-a-prolapsed-mitral-valve
#16
Shri Ram Sharma, Hibu Habung, Masaraf Hussain
No abstract text is available yet for this article.
July 2016: Neurology India
https://www.readbyqxmd.com/read/27239934/-current-approaches-to-diagnosing-and-treating-eosinophilic-granulomatosis-with-polyangiitis-the-2015-international-guidelines
#17
REVIEW
T V Beketova, M Yu Volkov, E L Nasonov
The 2015 international guidelines for the diagnosis and treatment of eosinophilic granulomatosis with polyangiitis, formerly known as the Churg-Strauss syndrome, are detailed and an attempt is made to expand an evidence base, by attracting more recent available publications. The new guidelines should not be regarded as final standards; these are primarily to extend the possibilities of choosing a personified management strategy for patients with eosinophilic granulomatosis with polyangiitis and to serve as the starting point for further in-depth investigations...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27228637/churg-strauss-syndrome-singulair-or-silicone-or-both
#18
Paula R David, Amir Dagan, Maartje Colaris, Mintsje de Boer, Jan W Cohen Tervaert, Yehuda Shoenfeld
No abstract text is available yet for this article.
March 2016: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/27191665/optimal-therapy-and-prospects-for-new-medicines-in-eosinophilic-granulomatosis-with-polyangiitis-churg-strauss-syndrome
#19
Christian Pagnoux, Matthieu Groh
INTRODUCTION: The prevalence of eosinophilic granulomatosis with polyangiitis (EGPA; previously known as Churg-Strauss syndrome) is lower than that of other antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV's), and only a few randomized controlled trials have been conducted for this rare disease. However, recent international efforts have helped delineate the best treatment approach. AREAS COVERED: At present, EGPA conventional therapy is by default similar to that of other AAVs...
October 2016: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/27116493/acute-lid-swelling-a-series-of-unusual-cases-treatment-and-follow-up
#20
G Shojaati, K Chaloupka
BACKGROUND: There are many different aetiologies for acute lid swelling, including infection, inflammation, degeneration, tumours and trauma. We present five uncommon cases of acute lid swelling and give an overview of differential diagnoses for rapidly evolving eyelid swelling. HISTORY AND SIGNS: We reviewed the charts of five patients with initial presentation of acute lid swelling. For the five patients, there were diagnoses of Churg Strauss syndrome, an allergic reaction to hyaluronic acid, lymphangioma, a ruptured dermoid cyst and a co-infected pre-existing orbital lesion that was only evident in the follow-up...
April 2016: Klinische Monatsblätter Für Augenheilkunde
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