keyword
https://read.qxmd.com/read/38643958/persistent-or-new-cytopenias-predict-relapse-better-than-routine-bone-marrow-aspirate-evaluations-after-hematopoietic-cell-transplantation-for-acute-leukemia-or-myelodysplastic-syndrome-in-children-and-young-adult-patients
#1
JOURNAL ARTICLE
Nancy A Kernan, Elizabeth Klein, Audrey Mauguen, Joanne Torok-Castanza, Susan E Prockop, Andromachi Scaradavou, Kevin Curran, Barbara Spitzer, Maria Cancio, Julie Ruggiero, Jennifer Allen, Andrew Harris, Joseph Oved, Richard J O'Reilly, Jaap Jan Boelens
BACKGROUND: The clinical value of serial routine bone marrow aspirates (rBMAs) in the first year after allogeneic hematopoietic cell transplantation (alloHCT) to detect or predict relapse of acute leukemia (AL) and myelodysplastic syndrome (MDS) in pediatric and young adult patients is unclear. OBJECTIVE: The purpose of this analysis was to determine if assessment of minimal residual disease (MRD) by multiparameter flow cytometry (MFC, MFC-MRD) or donor chimerism (DC) in rBMAs or serial CBCs done in the year after alloHCT predicted relapse of AL or MDS in pediatric and young adult patients...
April 20, 2024: Transplantation and cellular therapy
https://read.qxmd.com/read/38642806/a-single-joint-multi-task-motor-imagery-eeg-signal-recognition-method-based-on-empirical-wavelet-and-multi-kernel-extreme-learning-machine
#2
JOURNAL ARTICLE
Shan Guan, Longkun Cong, Fuwang Wang, Tingrui Dong
BACKGROUND: In the pursuit of finer Brain-Computer Interface commands, research focus has shifted towards classifying EEG signals for multiple tasks. While single-joint multitasking motor imagery provides support, distinguishing between EEG signals from the same joint remains challenging due to their similar brain spatial distribution. NEW METHOD: We designed experiments involving three motor imagery tasks-wrist extension, wrist flexion, and wrist abduction-with six participants...
April 18, 2024: Journal of Neuroscience Methods
https://read.qxmd.com/read/38638076/unveiling-a-novel-decomposition-pathway-in-propylene-carbonate-based-supercapacitors-insights-from-a-jelly-roll-configuration-study
#3
JOURNAL ARTICLE
Phatsawit Wuamprakhon, Jiraporn Phojaroen, Thitiphum Sangsanit, Kanruthai Santiyuk, Kan Homlamai, Worapol Tejangkura, Montree Sawangphruk
This research elucidates novel insights into the electrochemical properties and degradation phenomena of propylene carbonate (PC)-based supercapacitors at a large-scale 18650 cylindrical jelly-roll cell level. Central to our findings is the identification of 2-ethyl-4-methyl-1,3-dioxolane (EMD) as a hitherto undocumented decomposition by-product, highlighting the nuanced complexity of PC electrolyte stability. We further demonstrate that elevated operational voltages precipitate accelerated electrolyte degradation, underscoring the criticality of defining the operational voltage window for maximizing device longevity...
April 18, 2024: ChemSusChem
https://read.qxmd.com/read/38619549/improved-empirical-mode-decomposition-method-based-on-amplitude-frequency-characteristic-of-vortex-signals
#4
JOURNAL ARTICLE
Jie Chen, Fu-Rong Tian, Bin Li, Wei Zhang, Shu-Xu Wan, Xue-Qing Hou
The vortex flowmeter occupies a vital position in flow measurement with its unique advantages. It is essentially a fluid vibration instrument, and its measurement process is susceptible to interference, which seriously affects measurement accuracy. In particular, at low flow rates, it is an urgent problem to extract vortex signals from the complex noise. Among many signal processing methods, Empirical Mode Decomposition (EMD) is a time-frequency analysis method suitable for nonlinear, non-stationary signals...
April 1, 2024: Review of Scientific Instruments
https://read.qxmd.com/read/38616361/characteristics-and-treatment-of-acute-myeloid-neoplasms-with-cutaneous-involvement-in-infants-up-to-6%C3%A2-months-of-age-a-retrospective-study
#5
JOURNAL ARTICLE
Juliette Renaud, Bianca F Goemans, Franco Locatelli, Martina Pigazzi, Shelagh Redmond, Claudia E Kuehni, Alice Destaillats, Todd A Alonzo, Robert B Gerbing, Alan Gamis, Richard Aplenc, Raffaele Renella, Todd Cooper, Francesco Ceppi
BACKGROUND: Myeloid neoplasms account for 50% of cases of pediatric leukemias in infants. Approximately 25%-50% of patients with newborn leukemia have cutaneous extramedullary disease (EMD). In less than 10% of patients, aleukemic leukemia cutis or isolated extramedullary disease with cutaneous involvement (cEMD) occurs when skin lesions appear prior to bone marrow involvement and systemic symptoms. Interestingly, in acute myeloid leukemia with cutaneous EMD (AML-cEMD) and cEMD, spontaneous remissions have been reported...
April 14, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38610553/global-navigation-satellite-system-receiver-positioning-in-harsh-environments-via-clock-bias-prediction-by-empirical-mode-decomposition-and-back-propagation-neural-network-method
#6
JOURNAL ARTICLE
Libin Du, Hao Chen, Yibo Yuan, Longjiang Song, Xiangqian Meng
This paper proposes a novel method to improve the clock bias short-term prediction accuracy of navigation receivers then solve the problem of low positioning accuracy when the satellite signal quality deteriorates. Considering that the clock bias of a navigation receiver is equivalent to a virtual satellite, the predicted value of clock bias is used to assist navigation receivers in positioning. Consequently, a combined prediction method for navigation receiver clock bias based on Empirical Mode Decomposition (EMD) and Back Propagation Neural Network (BPNN) analysis theory is demonstrated...
April 7, 2024: Sensors
https://read.qxmd.com/read/38609970/left-ventricular-free-wall-rupture-caused-by-myocardial-ischemia-without-treatable-atherosclerotic-coronary-disease-a-case-series
#7
JOURNAL ARTICLE
Terézia B Andrási, Nunijiati Abudureheman, Alannah C Glück, Kai Dielmann, Gerhard Dinges
BACKGROUND: The clinical presentation of left ventricular free wall rupture (LVFWR) varies ranging from uneventful condition to congestive heart failure. Here we report two cases of LVFWR with different clinical presentation and notable outcome. A 53-year-old male presenting emergently with signs of myocardial infarction received immediate coronary angiography and thoracic CT-scan showing occlusion of the first marginal coronary branch without possibility of revascularization and minimal pericardial extravasation...
April 12, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38609788/emergency-medical-dispatch-technologies-addressing-communication-challenges-and-coordinating-emergency-response-in-low-and-middle-income-countries
#8
JOURNAL ARTICLE
Jason Friesen, Ramu Kharel, Peter G Delaney
A majority of emergency response in low and middle-income countries (LMICs) without formal emergency medical services (EMS) rely on uncoordinated layperson first responders (LFRs) to respond to emergencies using readily available mobile phones and private transport. Although formally trained LFRs are an important foundation for nascent emergency medical services (EMS) development, without coordination by standardized emergency medical dispatch (EMD) systems, LFR response is limited to witnessed emergencies, which provides significant but incomplete coverage...
April 11, 2024: Surgery
https://read.qxmd.com/read/38599183/exploring-the-potential-of-pretrained-cnns-and-time-frequency-methods-for-accurate-epileptic-eeg-classification-a-comparative-study
#9
JOURNAL ARTICLE
Mudasir Jamil, Muhammad Zulkifal Aziz, Xiaojun Yu
Prompt diagnosis of epilepsy relies on accurate classification of automated electroencephalogram (EEG) signals. Several approaches have been developed to characterize epileptic EEG data; however, none of them have exploited time-frequency data to evaluate the effect of tweaking parameters in pretrained frameworks for EEG data classification. This study compares the performance of several pretrained convolutional neural networks (CNNs) namely, AlexNet, GoogLeNet, MobileNetV2, ResNet-18 and SqueezeNet for the localization of epilepsy EEG data using various time-frequency data representation algorithms...
April 10, 2024: Biomedical Physics & Engineering Express
https://read.qxmd.com/read/38585902/space-swift-phenotypic-analysis-of-cells-an-open-source-single-cell-analysis-of-cell-painting-data
#10
Fabio Stossi, Pankaj K Singh, Michela Marini, Kazem Safari, Adam T Szafran, Alejandra Rivera Tostado, Christopher D Candler, Maureen G Mancini, Elina A Mosa, Michael J Bolt, Demetrio Labate, Michael A Mancini
Phenotypic profiling by high throughput microscopy has become one of the leading tools for screening large sets of perturbations in cellular models. Of the numerous methods used over the years, the flexible and economical Cell Painting (CP) assay has been central in the field, allowing for large screening campaigns leading to a vast number of data-rich images. Currently, to analyze data of this scale, available open-source software ( i.e. , CellProfiler) requires computational resources that are not available to most laboratories worldwide...
March 26, 2024: bioRxiv
https://read.qxmd.com/read/38570942/hypercolorization-propagating-spatially-sparse-noisy-spectral-clues-for-reconstructing-hyperspectral-images
#11
JOURNAL ARTICLE
M Kerem Aydin, Qi Guo, Emma Alexander
Hyperspectral cameras face challenging spatial-spectral resolution trade-offs and are more affected by shot noise than RGB photos taken over the same total exposure time. Here, we present a colorization algorithm to reconstruct hyperspectral images from a grayscale guide image and spatially sparse spectral clues. We demonstrate that our algorithm generalizes to varying spectral dimensions for hyperspectral images, and show that colorizing in a low-rank space reduces compute time and the impact of shot noise...
March 25, 2024: Optics Express
https://read.qxmd.com/read/38560116/improved-empirical-mode-decomposition-bagging-rcsp-combined-with-fisher-discriminant-method-for-eeg-feature-extraction-and-classification
#12
JOURNAL ARTICLE
Dongyi Chen
BACKGROUND: Traditional Common Spatial Pattern (CSP) algorithms for Electroencephalogram (EEG) signal classification are sensitive to noise and can produce low accuracy in small sample datasets. NEW METHOD: To solve the problem, an improved Empirical Mode Decomposition (EMD) Bagging Regularized CSP (RCSP) algorithm is proposed. It filters EEG signals through improved EMD, inhibits high-frequency noise, retains effective information in the characteristic frequency band, and uses Bagging algorithm for data reconstruction...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38555253/relation-of-plasma-neuropeptide-y-with-myocardial-function-and-infarct-severity-in-acute-st-elevation-myocardial-infarction
#13
JOURNAL ARTICLE
Christina Tiller, Martin Reindl, Magdalena Holzknecht, Ivan Lechner, Felix Troger, Fritz Oberhollenzer, Sebastian von der Emde, Thomas Kremser, Agnes Mayr, Axel Bauer, Bernhard Metzler, Sebastian J Reinstadler
BACKGROUND: Acute myocardial infarction is associated with the release of the co-transmitter neuropeptide-Y (NPY). NPY acts as a potent vasoconstrictor and is associated with microvascular dysfunction after ST-elevation myocardial infarction (STEMI). This study comprehensively evaluated the association of plasma NPY with myocardial function and infarct severity, visualized by cardiac magnetic resonance (CMR) imaging, in STEMI patients revascularized by primary percutaneous coronary intervention (PCI)...
March 29, 2024: European Journal of Internal Medicine
https://read.qxmd.com/read/38543989/estimating-rotational-acceleration-in-shoulder-and-elbow-joints-using-a-transformer-algorithm-and-a-fusion-of-biosignals
#14
JOURNAL ARTICLE
Yu Bai, Xiaorong Guan, Long He, Zheng Wang, Zhong Li, Meng Zhu
In the present study, we used a transformer model and a fusion of biosignals to estimate rotational acceleration in elbow and shoulder joints. To achieve our study objectives, we proposed a mechanomyography (MMG) signal isolation technique based on a variational mode decomposition (VMD) algorithm. Our results show that the VMD algorithm delivered excellent performance in MMG signal extraction compared to the commonly used technique of empirical mode decomposition (EMD). In addition, we found that transformer models delivered estimates of joint acceleration that were more precise than those produced by mainstream time series forecasting models...
March 7, 2024: Sensors
https://read.qxmd.com/read/38541178/regeneration-of-rabbit-calvarial-defects-with-combination-of-stem-cells-and-enamel-matrix-derivative-a-microcomputed-tomography-and-histological-evaluation-comparing-two-and-three-dimensional-cell-constructs
#15
JOURNAL ARTICLE
Kyung-Hwan Na, Hyun-Jin Lee, Ji-Eun Lee, Jun-Beom Park
Background and Objectives : This study addresses the challenge of bone regeneration in calvarial defects, exploring the efficacy of stem cell-based therapies and enamel matrix derivative (EMD) in tissue engineering. It assesses the regenerative potential of two- and three-dimensional cell constructs combined with mesenchymal stem cells (MSCs) and EMD in rabbit calvarial defects. Materials and Methods : This research involved the use of bone-marrow-derived MSCs cultured in silicon elastomer-based concave microwells to form spheroids...
March 8, 2024: Medicina
https://read.qxmd.com/read/38530855/synergistic-difference-in-the-effect-of-stretching-on-electromechanical-delay-components
#16
JOURNAL ARTICLE
Nicholas Toninelli, Giuseppe Coratella, Stefano Longo, Giulia M Romani, Christian Doria, Susanna Rampichini, Eloisa Limonta, Fabio Esposito, Emiliano Cè
This study investigated the synergistic difference in the effect of stretching on electromechanical delay (EMD) and its components, using a simultaneous recording of electromyographic, mechanomyographic, and force signals. Twenty-six healthy men underwent plantar flexors passive stretching. Before and after stretching, the electrochemical and mechanical components of the EMD and the relaxation EMD (R-EMD) were calculated in gastrocnemius medialis (GM), lateralis (GL) and soleus (SOL) during a supramaximal motor point stimulation...
2024: PloS One
https://read.qxmd.com/read/38529002/superior-oblique-muscle-extramedullary-plasmacytoma-in-a-patient-with-multiple-myeloma-and-a-review-of-literature
#17
Amirreza Veisi, Kimia Daneshvar, Sadid Hooshmandi, Maryam Najafi, Peyman Mohammadi Torbati, Kiana Hassanpour
INTRODUCTION: Multiple myeloma (MM), a plasma cell malignancy, is a systemic disease affecting various body organs. Plasmacytoma of bone and extramedullary disease (EMD) are presentations of MM. EMD is usually the sign of a more aggressive form of the disease. Herein, we report a patient with refractory MM presenting with extramedullary plasmacytoma in the superior oblique (SO) muscle. CASE PRESENTATION: A 51-year-old female presented complaining of gradual protrusion of the left eye and ocular pain from 20 days prior...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38525882/artificial-intelligence-to-advance-acute-and-intensive-care-medicine
#18
JOURNAL ARTICLE
Laurens A Biesheuvel, Dave A Dongelmans, Paul W G Elbers
PURPOSE OF REVIEW: This review explores recent key advancements in artificial intelligence for acute and intensive care medicine. As artificial intelligence rapidly evolves, this review aims to elucidate its current applications, future possibilities, and the vital challenges that are associated with its integration into emergency medical dispatch, triage, medical consultation and ICUs. RECENT FINDINGS: The integration of artificial intelligence in emergency medical dispatch (EMD) facilitates swift and accurate assessment...
March 14, 2024: Current Opinion in Critical Care
https://read.qxmd.com/read/38515784/mormyrid-fish-as-models-for-investigating-sensory-motor-integration-a-behavioural-perspective
#19
REVIEW
S Skeels, G von der Emde, T Burt de Perera
Animals possess senses which gather information from their environment. They can tune into important aspects of this information and decide on the most appropriate response, requiring coordination of their sensory and motor systems. This interaction is bidirectional. Animals can actively shape their perception with self-driven motion, altering sensory flow to maximise the environmental information they are able to extract. Mormyrid fish are excellent candidates for studying sensory-motor interactions, because they possess a unique sensory system (the active electric sense) and exhibit notable behaviours that seem to be associated with electrosensing...
April 2023: Journal of Zoology: Proceedings of the Zoological Society of London
https://read.qxmd.com/read/38509989/retina-images-classification-based-on-2d-empirical-mode-decomposition-and-multifractal-analysis
#20
JOURNAL ARTICLE
Lei Yang, Minxuan Zhang, Jing Cheng, Tiegang Zhang, Feng Lu
Diabetic retinopathy is an ocular disease caused by long-term damage to the retina due to high blood sugar levels. Elevated blood sugar can impair the microvasculature in the retina, leading to vascular abnormalities and the formation of abnormal new blood vessels. These changes can manifest in the retina as hemorrhages, leaks, vessel dilation, retinal edema, and retinal detachment. The retinas of individuals with diabetes exhibit different morphologies compared to those without the condition. Most histological images cannot be accurately described using traditional geometric shapes or methods...
March 30, 2024: Heliyon
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