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https://www.readbyqxmd.com/read/28533614/the-effect-of-bridge-exercise-method-on-the-strength-of-rectus-abdominis-muscle-and-the-muscle-activity-of-paraspinal-muscles-while-doing-treadmill-walking-with-high-heels
#1
Taewook Kang, Jaeseok Lee, Junghoon Seo, Dongwook Han
[Purpose] The purpose of this research is to investigate the effect of the method of bridge exercise on the change of rectus abdominis muscle and the muscle activity of paraspinal muscles while doing treadmill walking with high heels. [Subjects and Methods] The subjects of this research are healthy female students consisting of 10 persons performing bridge exercises in a supine group, 10 persons performing bridge exercises in a prone group, and 10 persons in a control group while in S university in Busan. Bridge exercise in supine position is performed in hook lying position...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28531879/scaffold-requirements-for-periodontal-regeneration-with-enamel-matrix-derivative-proteins
#2
Alessandra Apicella, Peggy Heunemann, Laurent Dejace, Matteo Marascio, Christopher J G Plummer, Peter Fischer
Periodontitis affects the attachment of natural teeth, and infection or inflammation associated with periodontitis may affect peri-implant tissues. Enamel matrix derivative (EMD) proteins provide stimulation for self-regeneration of the damaged tissue when applied to wide intrabony defects as part of a mixture with bone graft material. As a first step of the process enhancing cell proliferation and ligament formation, we demonstrated that EMD protein precipitation depends strongly on the physical and chemical characteristics of the bone grafts used in the mixture...
May 9, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28530525/cost-effectiveness-of-nivolumab-ipilimumab-combination-therapy-compared-with-monotherapy-for-first-line-treatment-of-metastatic-melanoma-in-the-united-states
#3
Anna Oh, Dang M Tran, Leann C McDowell, Dor Keyvani, Jay Andrew Barcelon, Oscar Merino, Leslie Wilson
BACKGROUND: The approval of new immunotherapies has dramatically changed the treatment landscape of metastatic melanoma. These survival gains come with trade-offs in side effects and costs, as well as important considerations for third-party payer systems, physicians, and patients. OBJECTIVE: To develop a Markov model to determine the cost-effectiveness of nivolumab, ipilimumab, and nivolumab-ipilimumab combination as firstline therapy in metastatic melanoma, while accounting for differential effectiveness in programmed death-ligand 1 (PD-L1) positive and negative patients...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28529760/denoising-techniques-in-adaptive-multi-resolution-domains-with-applications-to-biomedical-images
#4
Salim Lahmiri
Variational mode decomposition (VMD) is a new adaptive multi-resolution technique suitable for signal denoising purpose. The main focus of this work has been to study the feasibility of several image denoising techniques in empirical mode decomposition (EMD) and VMD domains. A comparative study is made using 11 techniques widely used in the literature, including Wiener filter, first-order local statistics, fourth partial differential equation, nonlinear complex diffusion process, linear complex diffusion process (LCDP), probabilistic non-local means, non-local Euclidean medians, non-local means, non-local patch regression, discrete wavelet transform and wavelet packet transform...
February 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28529759/high-frequency-based-features-for-low-and-high-retina-haemorrhage-classification
#5
Salim Lahmiri
Haemorrhages (HAs) presence in fundus images is one of the most important indicators of diabetic retinopathy that causes blindness. In this regard, accurate grading of HAs in fundus images is crucial for appropriate medical treatment. The purpose of this Letter is to assess the relative performance of statistical features obtained with three different multi-resolution analysis (MRA) techniques and fed to support vector machine in grading retinal HAs. Considered MRA techniques are the common discrete wavelet transform (DWT), empirical mode decomposition (EMD), and variational mode decomposition (VMD)...
February 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28504702/pgbd5-promotes-site-specific-oncogenic-mutations-in-human-tumors
#6
Anton G Henssen, Richard Koche, Jiali Zhuang, Eileen Jiang, Casie Reed, Amy Eisenberg, Eric Still, Ian C MacArthur, Elias Rodríguez-Fos, Santiago Gonzalez, Montserrat Puiggròs, Andrew N Blackford, Christopher E Mason, Elisa de Stanchina, Mithat Gönen, Anne-Katrin Emde, Minita Shah, Kanika Arora, Catherine Reeves, Nicholas D Socci, Elizabeth Perlman, Cristina R Antonescu, Charles W M Roberts, Hanno Steen, Elizabeth Mullen, Stephen P Jackson, David Torrents, Zhiping Weng, Scott A Armstrong, Alex Kentsis
Genomic rearrangements are a hallmark of human cancers. Here, we identify the piggyBac transposable element derived 5 (PGBD5) gene as encoding an active DNA transposase expressed in the majority of childhood solid tumors, including lethal rhabdoid tumors. Using assembly-based whole-genome DNA sequencing, we found previously undefined genomic rearrangements in human rhabdoid tumors. These rearrangements involved PGBD5-specific signal (PSS) sequences at their breakpoints and recurrently inactivated tumor-suppressor genes...
May 15, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28499122/emd-dwt-based-transform-domain-feature-reduction-approach-for-quantitative-multi-class-classification-of-breast-lesions
#7
Sharmin R Ara, Syed Khairul Bashar, Farzana Alam, Md Kamrul Hasan
Using a large set of ultrasound features does not necessarily ensure improved quantitative classification of breast tumors; rather, it often degrades the performance of a classifier. In this paper, we propose an effective feature reduction approach in the transform domain for improved multi-class classification of breast tumors. Feature transformation methods, such as empirical mode decomposition (EMD) and discrete wavelet transform (DWT), followed by a filter- or wrapper-based subset selection scheme are used to extract a set of non-redundant and more potential transform domain features through decorrelation of an optimally ordered sequence of N ultrasonic bi-modal (i...
April 24, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28477366/addition-of-enamel-matrix-derivatives-to-bone-substitutes-for-the-treatment-of-intrabony-defects-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#8
REVIEW
Giuseppe Troiano, Luigi Laino, Khrystyna Zhurakivska, Marco Cicciù, Lorenzo Lo Muzio, Lucio Lo Russo
AIM: In order to enhance clinical improvement of intrabony defects, the addition of enamel matrix derivatives (EMD) to a bone substitues (BS) has been investigated. The aim of this systematic review is to figure out whether or not such a combination, in comparison to the treatment with a BS alone has beneficial effects on the following outcomes: clinical attachment level (CAL) gain, probing depth (PD) reduction and recession (REC). METHODS: Electronic databases (PUBMED, SCOPUS, EBSCO Host Research Databases and Web Of Knowledge) were searched for randomized controlled trials in humans addressing the use of a combination of BS and EMD versus a control group with BS alone for the treatment of intrabony defects, with a minimum of six months; meta-analysis and trial sequential analysis were then performed...
May 6, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28474322/%C3%AE-tcp-ha-with-or-without-enamel-matrix-proteins-for-maxillary-sinus-floor-augmentation-a-histomorphometric-analysis-of-human-biopsies
#9
James Carlos Nery, Luís Antônio Violin Dias Pereira, George Furtado Guimarães, Cassio Rocha Scardueli, Fabiana Mantovani Gomes França, Rubens Spin-Neto, Andreas Stavropoulos
BACKGROUND: It is still unclear whether enamel matrix proteins (EMD) as adjunct to bone grafting enhance bone healing. This study compared histomorphometrically maxillary sinus floor augmentation (MSFA) with β-TCP/HA in combination with or without EMD in humans. METHODS: In ten systemically healthy patients needing bilateral MSFA, one side was randomly treated using β-TCP/HA mixed with EMD (BC + EMD) and the other side using only β-TCP/HA (BC). After 6 months, biopsies were harvested from grafted areas during implant installation, being histologically and histomorphometrically analyzed...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28470386/human-gingival-fibroblast-response-to-enamel-matrix-derivative-porcine-recombinant-21-3-kda-amelogenin-and-5-3-kda-tyrosine-rich-amelogenin-peptide
#10
Marzena Wyganowska-Swiatkowska, Paulina Urbaniak, Daniel Lipinski, Marlena Szalata, Malgorzata Kotwicka
Enamel matrix derivative (EMD) containing a variety of protein fractions has been used for periodontal tissue regeneration. It is suggested that the proteins contained in EMD positively influence gingival fibroblasts migration and proliferation. Effects of EMD as well as of porcine recombinated 21.3-kDa amelogenin (prAMEL) and 5.3-kDa tyrosine-rich amelogenin peptide (prTRAP) on human gingival fibroblast (HGF-1, ATCC; USA) cell line were investigated. Real-time cell analysis (xCELLigence system; Roche Applied Science) was performed to determine the effects of EMD, prAMEL and prTRAP (12...
May 3, 2017: Human Cell
https://www.readbyqxmd.com/read/28469733/thermal-conductivity-engineering-of-bulk-and-one-dimensional-si-ge-nanoarchitectures
#11
Ali Kandemir, Ayberk Ozden, Tahir Cagin, Cem Sevik
Various theoretical and experimental methods are utilized to investigate the thermal conductivity of nanostructured materials; this is a critical parameter to increase performance of thermoelectric devices. Among these methods, equilibrium molecular dynamics (EMD) is an accurate technique to predict lattice thermal conductivity. In this study, by means of systematic EMD simulations, thermal conductivity of bulk Si-Ge structures (pristine, alloy and superlattice) and their nanostructured one dimensional forms with square and circular cross-section geometries (asymmetric and symmetric) are calculated for different crystallographic directions...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28468250/analysis-of-gamma-band-activity-from-human-eeg-using-empirical-mode-decomposition
#12
Carlos Amo, Luis de Santiago, Rafael Barea, Almudena López-Dorado, Luciano Boquete
The purpose of this paper is to determine whether gamma-band activity detection is improved when a filter, based on empirical mode decomposition (EMD), is added to the pre-processing block of single-channel electroencephalography (EEG) signals. EMD decomposes the original signal into a finite number of intrinsic mode functions (IMFs). EEGs from 25 control subjects were registered in basal and motor activity (hand movements) using only one EEG channel. Over the basic signal, IMF signals are computed. Gamma-band activity is computed using power spectrum density in the 30-60 Hz range...
April 29, 2017: Sensors
https://www.readbyqxmd.com/read/28463278/extracting-and-compensating-for-fog-vibration-error-based-on-improved-empirical-mode-decomposition-with-masking-signal
#13
Xiyuan Chen, Wei Wang
Vibration is an important error source in fiber-optic gyroscopes (FOGs), and the extraction and compensation of vibration signals are important ways to eliminate the error and improve the accuracy of FOG. To decompose the vibration signal better, a new algorithm based on empirical mode decomposition (EMD) with masking signal is proposed in this paper. The masking signal is a kind of sinusoidal signal, and the frequency and amplitude of the masking signal are selected using improved particle swarm optimization...
May 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/28458786/large-plasmacytoma-occupying-the-upper-limb-in-a-myeloma-patient
#14
Junichiro Takano, Kensuke Ohikata, Daisuke Nagase, Toru Igari, Kazuhiko Natori, Shotaro Hagiwara
Extramedullary disease (EMD) is an issue for patients with multiple myeloma (MM), since extramedullary spread of MM is associated with an aggressive course and a poor prognosis. Moreover, the mechanism of EMD development is uncertain. Here, we present extensive extramedullary plasmacytoma occupying the left upper limb of a 66-year-old female patient with MM with an extremely aggressive course and multiple visceral organ involvement without bone marrow infiltration or plasma cell leukemia. EMD of this large size is extremely rare and this case may provide a clue for better understanding of clinical features of EMD in MM...
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28456944/avelumab-first-global-approval
#15
Esther S Kim
Avelumab (Bavencio(®)) is an intravenously administered programmed cell death ligand-1-blocking human antibody initially developed by EMD Serono Inc. (the biopharmaceutical division of Merck KGaA, Darmstadt, Germany) [now jointly developed and commercialized by EMD Serono Inc. and Pfizer] for the treatment of various tumours. It has received accelerated approval in the USA for the treatment of metastatic Merkel cell carcinoma (mMCC) in adults and paediatric patients aged ≥12 years. The marketing authorization application for avelumab in the treatment of mMCC is undergoing regulatory review in the EU, the biologics license application for avelumab in the treatment of urothelial carcinoma is undergoing priority review by the FDA, and avelumab is in various stages of development internationally for a variety of cancers...
May 2017: Drugs
https://www.readbyqxmd.com/read/28433870/automated-detection-of-premature-delivery-using-empirical-mode-and-wavelet-packet-decomposition-techniques-with-uterine-electromyogram-signals
#16
U Rajendra Acharya, Vidya K Sudarshan, Soon Qing Rong, Zechariah Tan, Choo Min Lim, Joel Ew Koh, Sujatha Nayak, Sulatha V Bhandary
An accurate detection of preterm labor and the risk of preterm delivery before 37 weeks of gestational age is crucial to increase the chance of survival rate for both mother and the infant. Thus, the uterine contractions measured using uterine electromyogram (EMG) or electro hysterogram (EHG) need to have high sensitivity in the detection of true preterm labor signs. However, visual observation and manual interpretation of EHG signals at the time of emergency situation may lead to errors. Therefore, the employment of computer-based approaches can assist in fast and accurate detection during the emergency situation...
April 18, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28432030/effects-of-mixed-proximal-and-distal-topogenic-signals-on-the-topological-sensitivity-of-a-membrane-protein-to-the-lipid-environment
#17
Heidi Vitrac, William Dowhan, Mikhail Bogdanov
The final topology of membrane proteins is thought to be dictated primarily by the encoding sequence. However, according to the Charge Balance Rule the topogenic signals within nascent membrane proteins are interpreted in agreement with the Positive Inside Rule as influenced by the protein phospholipid environment. The role of long-range protein-lipid interactions in establishing a final uniform or dual topology is unknown. In order to address this role, we determined the positional dependence of the potency of charged residues as topological signals within Escherichia coli sucrose permease (CscB) in cells in which the zwitterionic phospholipid phosphatidylethanolamine (PE), acting as topological determinant, was either eliminated or tightly titrated...
July 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28409655/9-1-1-triage-of-non-traumatic-chest-pain-association-with-hospital-diagnosis
#18
Greg Scott, Jeff J Clawson, Isabel Gardett, Meghan Broadbent, Nathan Williams, Conrad Fivaz, Gigi Marshall, Tracey Barron, Christopher Olola
OBJECTIVE: Chest pain is one of the most common reasons people seek emergency care-and one of the most critical. In the United States, chest pain is the second most common reason for emergency department (ED) visits. A patient's primary complaint of "chest pain" may reflect a broad range of underlying causes; therefore, it is important that emergency medical service (EMS) agencies gain a thorough understanding of these cases, beginning with the initial management of chest pain in the 9-1-1 center...
April 14, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28396887/comparison-of-enamel-matrix-derivative-emdogain-and-subepithelial-connective-tissue-graft-for-root-coverage-in-patients-with-multiple-gingival-recession-defects-a-randomized-controlled-clinical-study
#19
Angeliki Alexiou, Ioannis Vouros, Georgios Menexes, Antonis Konstantinidis
OBJECTIVE: The purpose of the present study was to compare the clinical efficiency of enamel matrix derivative (EMD) placed under a coronally advanced flap (CAF; test group), to a connective tissue graft (CTG) placed under a CAF (control group), in patients with multiple recession defects. METHOD AND MATERIALS: Twelve patients with multiple Miller's Class I or II gingival recessions in contralateral quadrants of the maxilla were selected. The primary outcome variable was the change in depth of the buccal recession (REC), at 6 months (T6) after surgery...
2017: Quintessence International
https://www.readbyqxmd.com/read/28387703/the-identification-of-the-deformation-stage-of-a-metal-specimen-based-on-acoustic-emission-data-analysis
#20
Shenao Zou, Fengying Yan, Guoan Yang, Wei Sun
The acoustic emission (AE) signals of metal materials have been widely used to identify the deformation stage of a pressure vessel. In this work, Q235 steel samples with different propagation distances and geometrical structures are stretched to get the corresponding acoustic emission signals. Then the obtained acoustic emission signals are de-noised by empirical mode decomposition (EMD), and then decomposed into two different frequency ranges, i.e., one mainly corresponding to metal deformation and the other mainly corresponding to friction signals...
April 7, 2017: Sensors
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