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Shasha Yuan, Weidong Zhou, Junhui Li, Qi Wu
Epilepsy is a serious chronic neurological disorder, which affects more than 50 million people worldwide, and automatic seizure detection on EEG recordings is extremely required in the diagnosis and monitoring of epilepsy. This paper presents a novel seizure detection method using sparse representation-based Earth Mover's Distance (SR-EMD). In the proposed algorithm, wavelet decomposition is executed on the original EEG recordings with five scales, and the scales 3, 4 and 5 are selected to structure the distributions of EEG signals...
October 20, 2016: Medical & Biological Engineering & Computing
Eirin N Ellensen, Torben Wisborg, Steinar Hunskaar, Erik Zakariassen
BACKGROUND: The Emergency Medical Communication Centre (EMCC) operators in Norway report using the Norwegian Index for Medical Emergency Assistance (Index), a criteria-based dispatch guideline, in about 75 % of medical emergency calls. The main purpose of a dispatch guideline is to assist the operator in securing a correct response as quickly as possible. The effect of using the guideline on EMCC response interval is as yet unknown. We wanted to ascertain an objective measure of guideline adherence, and explore a possible effect on emergency medical dispatch (EMD) response interval...
October 13, 2016: BMC Emergency Medicine
Stephen Barnett, Joan Henderson, Adam Hodgkins, Christopher Harrison, Abhijeet Ghosh, Bridget Dijkmans-Hadley, Helena Britt, Andrew Bonney
BACKGROUND: Electronic medical data (EMD) from electronic health records of general practice computer systems have enormous research potential, yet many variables are unreliable. OBJECTIVE: The aim of this study was to compare selected data variables from general practice EMD with a reliable, representative national dataset (Bettering the Evaluation and Care of Health (BEACH)) in order to validate their use for primary care research. METHOD: EMD variables were compared with encounter data from the nationally representative BEACH program using χ (2) tests and robust 95% confidence intervals to test their validity (measure what they reportedly measure)...
October 12, 2016: HIM Journal
Emilio Salazar-Gatzimas, Juyue Chen, Matthew S Creamer, Omer Mano, Holly B Mandel, Catherine A Matulis, Joseph Pottackal, Damon A Clark
Animals estimate visual motion by integrating light intensity information over time and space. The integration requires nonlinear processing, which makes motion estimation circuitry sensitive to specific spatiotemporal correlations that signify visual motion. Classical models of motion estimation weight these correlations to produce direction-selective signals. However, the correlational algorithms they describe have not been directly measured in elementary motion-detecting neurons (EMDs). Here, we employed stimuli to directly measure responses to pairwise correlations in Drosophila's EMD neurons, T4 and T5...
October 5, 2016: Neuron
R I M Dunbar, Ben Teasdale, Jackie Thompson, Felix Budelmann, Sophie Duncan, Evert van Emde Boas, Laurie Maguire
Fiction, whether in the form of storytelling or plays, has a particular attraction for us: we repeatedly return to it and are willing to invest money and time in doing so. Why this is so is an evolutionary enigma that has been surprisingly underexplored. We hypothesize that emotionally arousing drama, in particular, triggers the same neurobiological mechanism (the endorphin system, reflected in increased pain thresholds) that underpins anthropoid primate and human social bonding. We show that, compared to subjects who watch an emotionally neutral film, subjects who watch an emotionally arousing film have increased pain thresholds and an increased sense of group bonding...
September 2016: Royal Society Open Science
Todd Chassee, Diann Reischmann, Michael Mancera, John D Hoyle
BACKGROUND: Prehospital pediatric drug dosing errors affect 56,000 U.S. children annually. An accurate weight is the first step in accurate dosing. To date, the accuracy of Emergency Medical Dispatcher (EMD) obtained weights has not been evaluated. We hypothesized that EMD could obtain accurate pediatric weights. METHODS: We used a convenience sample of patients 12 years and younger that were transported by EMS to one children's hospital. EMD obtained patient weight (DW) from the 9-1-1 caller...
September 30, 2016: Prehospital Emergency Care
L Shen, Y Sun, T Tong, H Zhang, L Liang, W Deng, G Li, J Zhu, Z Zhang
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Yong Zhang, Xiaomin Ji, Suhua Zhang
EEG signal has been widely used in emotion recognition. However, too many channels and extracted features are used in the current EEG-based emotion recognition methods, which lead to the complexity of these methods This paper studies on feature extraction on EEG-based emotion recognition model to overcome those disadvantages, and proposes an emotion recognition method based on empirical mode decomposition (EMD) and sample entropy. The proposed method first employs EMD strategy to decompose EEG signals only containing two channels into a series of intrinsic mode functions (IMFs)...
October 28, 2016: Neuroscience Letters
Nicole Y Engel, Victor U Weiss, Martina Marchetti-Deschmann, Günter Allmaier
In order to better understand biological events, lectin-glycoprotein interactions are of interest. The possibility to gather more information than the mere positive or negative response for interactions brought mass spectrometry into the center of many research fields. The presented work shows the potential of a nano-electrospray gas-phase electrophoretic mobility molecular analyzer (nES GEMMA) to detect weak, noncovalent, biospecific interactions besides still unbound glycoproteins and unreacted lectins without prior liquid phase separation...
September 19, 2016: Journal of the American Society for Mass Spectrometry
Raffy Dotan, Glenn Jenkins, Thomas D O'Brien, Steve Hansen, Bareket Falk
BACKGROUND: Compared with visual torque-onset-detection (TOD), threshold-based TOD produces onset bias, which increases with lower torques or rates of torque development (RTD). PURPOSE: To compare the effects of differential TOD-bias on common contractile parameters in two torque-disparate groups. METHODS: Fifteen boys and 12 men performed maximal, explosive, isometric knee-extensions. Torque and EMG were recorded for each contraction. Best contractions were selected by peak torque (MVC) and peak RTD...
September 1, 2016: Journal of Electromyography and Kinesiology
Jee Young Kim, Soo Ah Im, Ju Hyun Lee, Jae Wook Lee, Nak Gyun Chung, Bin Cho
BACKGROUND: Extramedullary relapse (EMR) is a recurrence of leukemia in sites other than the bone marrow, and it exhibits a relatively rare presentation of relapse of acute leukemia. However, EMR is an important cause of treatment failure among patients with acute leukemia. Therefore, early detection of these relapses may improve the prognosis. OBJECTIVES: To describe the disease-related demographic and clinical features and radiologic findings for children diagnosed with EMR in acute leukemia...
June 2016: Iranian Journal of Pediatrics
Taufiq K Ahmad Khairuddin, William R B Lionheart
Weakly electric fish generate electric current and use hundreds of voltage sensors on the surface of their body to navigate and locate food. Experiments (von der Emde and Fetz 2007 J. Exp. Biol. 210 3082-95) show that they can discriminate between differently shaped conducting or insulating objects by using electrosensing. One approach to electrically identify and characterize the object with a lower computational cost rather than full shape reconstruction is to use the first order polarization tensor (PT) of the object...
2016: Bioinspiration & Biomimetics
Robert N Emde
No abstract text is available yet for this article.
September 2016: Infant Mental Health Journal
Jeremy R Townsend, Jeffrey R Stout, Adam R Jajtner, David D Church, Kyle S Beyer, Leonardo P Oliveira, Michael B La Monica, Joshua J Riffe, Tyler W D Muddle, Kayla M Baker, David H Fukuda, Michael D Roberts, Jay R Hoffman
PURPOSE: The NF-κB signaling pathway regulates multiple cellular processes following exercise stress. This study aims to examine the effects of an acute lower-body resistance exercise protocol and subsequent recovery on intramuscular NF-κB signaling. METHODS: Twenty-eight untrained males were assigned to either a control (CON; n = 11) or exercise group (EX; n = 17) and completed a lower-body resistance exercise protocol consisting of the back squat, leg press, and leg extension exercises...
August 31, 2016: European Journal of Applied Physiology
Chezi Ganzel, Judith Manola, Dan Douer, Jacob M Rowe, Hugo F Fernandez, Elisabeth M Paietta, Mark R Litzow, Ju-Whei Lee, Selina M Luger, Hillard M Lazarus, Larry D Cripe, Martin S Tallman
PURPOSE: Extramedullary disease (EMD) at diagnosis in patients with acute myeloid leukemia (AML) has been recognized for decades. Reported herein are results from a large study of patients with AML who were treated in consecutive ECOG-ACRIN Cancer Research Group frontline clinical trials in an attempt to define the incidence and clinical implications of EMD. METHODS: Patients with newly diagnosed AML, age 15 years and older, who were treated in 11 clinical trials, were studied to identify EMD, as defined by physical examination, laboratory findings, and imaging results...
August 29, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Lina Abou-Abbas, Chakib Tadj, Christian Gargour, Leila Montazeri
This paper addresses the problem of automatic cry signal segmentation for the purposes of infant cry analysis. The main goal is to automatically detect expiratory and inspiratory phases from recorded cry signals. The approach used in this paper is made up of three stages: signal decomposition, features extraction, and classification. In the first stage, short-time Fourier transform, empirical mode decomposition (EMD), and wavelet packet transform have been considered. In the second stage, various set of features have been extracted, and in the third stage, two supervised learning methods, Gaussian mixture models and hidden Markov models, with four and five states, have been discussed as well...
August 24, 2016: Journal of Voice: Official Journal of the Voice Foundation
Eylem Ayhan Alkan, Gülay Tüter, Ateş Parlar, Ayşegül Yücel, Bülent Kurtiş
OBJECTIVES: This study compares peri-implant crevicular fluid (PICF) prostaglandin E2 (PGE2) levels, clinical parameters and implant stability quotient (ISQ) values around implants placed in augmented extraction sockets. MATERIALS AND METHODS: The sockets (24 in total) were randomly augmented using either EMD or Bio-Oss Collagen. Implant placements were performed after three months of healing. ISQ readings were evaluated at three points: at the time of surgery, at the first month and at the third month...
October 2016: Acta Odontologica Scandinavica
Zdena Malá, Petr Gebauer, Petr Boček
This article describes for the first time the combination of electrophoretic focusing on inverse electromigration dispersion (EMD) gradient, a new separation principle described in 2010, with electrospray-ionization (ESI) mass spectrometric detection. The separation of analytes along the electromigrating EMD profile proceeds so that each analyte is focused and concentrated within the profile at a particular position given by its pKa and ionic mobility. The proposed methodology combines this principle with the transport of the focused zones to the capillary end by superimposed electromigration, electroosmotic flow and ESI suction, and their detection by the MS detector...
September 7, 2016: Analytica Chimica Acta
Abdul Qadir Javaid, Hazar Ashouri, Alexis Dorier, Mozziyar Etemadi, J Alex Heller, Shuvo Roy, Omer T Inan
GOAL: Our objective is to provide a framework for extracting signals of interest from the wearable seismocardiogram (SCG) measured during walking at normal (subject's preferred pace) and moderately-fast (1.34 - 1.45 m/s) speeds. METHODS: We demonstrate, using empirical mode decomposition (EMD) and feature tracking algorithms, that the pre-ejection period (PEP) can be accurately estimated from a wearable patch that simultaneously measures electrocardiogram (ECG) and sternal acceleration signals...
August 16, 2016: IEEE Transactions on Bio-medical Engineering
Michael Schmitt, Angela G Hückelhoven, Michael Hundemer, Anita Schmitt, Susanne Lipp, Martina Emde, Hans Salwender, Mathias Hänel, Katja Weisel, Uta Bertsch, Jan Dürig, Anthony D Ho, Igor Wolfgang Blau, Hartmut Goldschmidt, Anja Seckinger, Dirk Hose
BACKGROUND: Raising T-cell response against antigens either expressed on normal and malignant plasma cells (e.g. HM1.24) or aberrantly on myeloma cells only (e.g. cancer testis antigens, CTA) by vaccination is a potential treatment approach for multiple myeloma. RESULTS: Expression by GEP is found for HM1.24 in all, HMMR in 318/458 (69.4%), MAGE-A3 in 209/458 (45.6%), NY-ESO-1/2 in 40/458 (8.7%), and WT-1 in 4/458 (0.8%) of samples with the pattern being confirmed by RNA-sequencing...
August 11, 2016: Oncotarget
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