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https://www.readbyqxmd.com/read/29147841/radiotherapy-for-extramedullary-leukaemic-manifestation-chloroma
#1
Michael Oertel, Khaled Elsayad, Uwe Haverkamp, Matthias Stelljes, Hans Theodor Eich
PURPOSE: Extramedullary leukaemic disease (EMD, synonym chloroma) is a rare solid manifestation of myeloid leukaemia for which the value of radiotherapy (RT) as a treatment strategy remains controversial. The aim of this study is to analyse the effectiveness of various RT doses for EMD in the modern treatment era. MATERIALS AND METHODS: Between January 2000 and June 2016, 20 patients with total of 45 lesions underwent RT for EMD at our institution. RESULTS: With a median radiation dose of 26 Gy (range 4-42 Gy), local remission could be achieved in 91% of patients (complete remission rate: 71%)...
November 16, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29111840/ecg-beat-classification-using-empirical-mode-decomposition-and-mixture-of-features
#2
Santanu Sahoo, Monalisa Mohanty, Suresh Behera, Sukanta Kumar Sabut
Computer-aided analysis is useful in predicting arrhythmia conditions of the heart by analysing the recorded ECG signals. In this work, we proposed a method to detect, extract informative features to classify six types of heartbeat of ECG signals obtained from the MIT-BIH Arrhythmia database. The powerful discrete wavelet transform (DWT) is used to eliminate different sources of noises. Empirical mode decomposition (EMD) with adaptive thresholding has been used to detect precise R-peaks and QRS complex. The significant features consists of temporal, morphological and statistical were extracted from the processed ECG signals and combined to form a set of features...
November 7, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29104382/clinical-and-radiographic-evaluation-of-four-different-pulpotomy-agents-in-primary-molars-a-longitudinal-study
#3
B Sunitha, Ravindar Puppala, Balaji Kethineni, Manoj K Mallela, Ravigna Peddi, P Tarasingh
Background: The medicament formocresol (FC) used for pulpotomy in primary teeth has great concerns regarding its toxicity due to one of its constituent formaldehyde which acts by tissue fixation. Therefore, new medicaments were introduced which claimed preservation and regeneration of pulp. Aim: The present study is aimed to compare and evaluate the clinical and radiographic success of FC, pulpotec, mineral trioxide aggregate (MTA), and emdogain (EMD) as pulpotomy medicaments in human primary molars...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29098548/influence-of-lvad-function-on-mechanical-unloading-and-electromechanical-delay-a-simulation-study
#4
Aulia Khamas Heikhmakhtiar, Ah Jin Ryu, Eun Bo Shim, Kwang-Soup Song, Natalia A Trayanova, Ki Moo Lim
This study hypothesized that a left ventricular assist device (LVAD) shortens the electromechanical delay (EMD) by mechanical unloading. The goal of this study is to examine, by computational modeling, the influence of LVAD on EMD for four heart failure (HF) cases ranging from mild HF to severe HF. We constructed an integrated model of an LVAD-implanted cardiovascular system, then we altered the Ca(2+) transient magnitude, with scaling factors 1, 0.9, 0.8, and 0.7 representing HF1, HF2, HF3, and HF4, respectively, in order of increasing HF severity...
November 3, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29097859/quantifying-burnout-among-emergency-medicine-professionals
#5
William Wilson, Jeffrey Pradeep Raj, Girish Narayan, Murtuza Ghiya, Shakuntala Murty, Bobby Joseph
Background: Burnout is a syndrome explained as serious emotional depletion with poor adaptation at work due to prolonged occupational stress. It has three principal components namely emotional exhaustion(EE), depersonalization(DP) and diminished feelings of personal accomplishment(PA). Thus, we aimed at measuring the degree of burnout in doctors and nurses working in emergency medicine department (EMD) of 4 select tertiary care teaching hospitals in South India. Methods: A cross sectional survey was conducted among EMD professionals using a 30-item standardized pilot tested questionnaire as well as the Maslach burnout inventory...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29072488/t3-sub-classification-using-the-emd-mesorectum-ratio-predicts-neoadjuvant-chemoradiation-outcome-in-t3-rectal-cancer-patients
#6
Lijun Shen, Yiqun Sun, Hui Zhang, Jing Zhang, Weijuan Deng, Yaqi Wang, Ye Yao, Lifeng Yang, Ji Zhu, Tong Tong, Liping Liang, Zhen Zhang
PURPOSE: To evaluate the feasibility of the EMD (extramural depth)/mesorectum ratio as a marker for T3 rectal cancer and its ability to predict tumor response to neoadjuvant chemoradiation and survival. METHODS: From 2010 to 2016, 284 T3 rectal cancer patients who underwent high resolution MRI before neoadjuvant chemoradiation were enrolled. The EMD was defined as the distance from the outer edge of the muscularis propria to the outermost edge of the tumor. The measurement of the tumor EMD and mesorectum was in the same layer and their ratio was calculated...
October 26, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29063955/novel-agent-based-salvage-autologous-stem-cell-transplantation-for-relapsed-multiple-myeloma
#7
Beatrice Anna Zannetti, Paola Tacchetti, Lucia Pantani, Barbara Gamberi, Patrizia Tosi, Serena Rocchi, Claudia Cellini, Sonia Ronconi, Annalisa Pezzi, Katia Mancuso, Ilaria Rizzello, Isola Caratozzolo, Marina Martello, Luca Dozza, Michele Cavo, Elena Zamagni
High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is a standard frontline therapy for multiple myeloma (MM). Therapeutic options for patients with relapsed MM after ASCT include novel agents in different combos, salvage ASCT (sASCT), and allogeneic transplant, with no unique standard of care. We retrospectively analyzed 66 MM patients who relapsed after up-front single or double ASCT(s) and received novel agent-based sASCT at five Italian centers. Median event-free survival from up-front ASCT(s) to first relapse (EFS1) was 44 months...
October 24, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29060984/-epidemiologic-and-spatio-temporal-characteristics-of-hepatitis-e-in-china-2004-2014
#8
Z Q Liu, J L Zuo, Q Yan, Q W Fang, T J Zhang
Objective: To describe and analyze the epidemiologic and spatio-temporal characteristics of hepatitis E in China from 2004 to 2014. Methods: Data on the incidence of hepatitis E in 31 provinces (municipality and autonomous region) from 2004 to 2014, were collected. Empirical Mode Decomposition (EMD) was applied to decompose the time-series data to accurately describe the trend of hepatitis E incidence. Mathematic model was used to estimate the annual change of incidence in each age group and the whole province...
October 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29060768/smooth-bandpass-empirical-mode-decomposition-with-rolling-ball-sifting-for-extracting-carotid-bruits-and-heart-sounds
#9
Adam Huang, Min-Yin Liu, Chung-Wei Lee, Hon-Man Liu
Carotid bruits are systolic sounds associated with turbulent blood flow through atherosclerotic stenosis in the neck. They are audible intermittent high-frequency sounds mixed with low-frequency heart sounds that wax and wane periodically. It is a nontrivial problem to extract both bruits and heart sounds with high fidelity for further computer-aided analysis. In this paper we propose a smooth bandpass empirical mode decomposition (EMD) method to tackle the problem in the time domain. First, bandpass EMD is achieved by using a rolling ball algorithm to sift the local extrema of chosen time-scales...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060641/performance-evaluation-of-noise-assisted-multivariate-empirical-mode-decomposition-and-its-application-to-multichannel-emg-signals
#10
Yi Zhang, Steven Su, Peng Xu, Dezhong Yao
The use of the Empirical Mode Decomposition (EMD) for nonlinear signal processing has been popularized in the recent years. However, its utility for the processing of multichannel Electromyography (EMG) signals is still limited. This paper investigates the decomposition performance of multichannel EMGs by using the EMD-based approaches, Ensemble EMD (EEMD), Multivariate EMD (MEMD), and Noise-Assisted MEMD (NA-MEMD). In the experiment, 11 male subjects undergo three exercise programs, leg extension from a sitting position, flexion of the leg up, and gait, while electrodes are placed on the muscle groups, biceps femoris, vastus medialis, rectus femoris, and semitendinosus...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060518/significance-of-modified-empirical-mode-decomposition-for-ecg-denoising
#11
Pratik Singh, S Shahnawazuddin, Gayadhar Pradhan
The primary objective of the presented work is to exploit the power of modified empirical mode decomposition (M-EMD) for the denoising of ECG signals. It is well known that the ECG signals get corrupted by a number of noises during the recording process. Especially, during wireless ECG recording and ambulatory patient monitoring, the signal gets corrupted by additive white Gaussian noise (AWGN). Over the years, several techniques have been proposed for ECG denoising. Among those, empirical mode decomposition (EMD) and nonlocal means (NLM) algorithm are noted to be quite effective...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060512/analysis-of-dynamic-antral-scintigraphy-using-empirical-mode-decomposition
#12
Panasun Ngamsirijit, Pisit Jarumaneeroj, Tawatchai Chaiwatanarat, Yothin Rakvongthai
In this work, we proposed to use the empirical mode decomposition (EMD) to analyze signals from dynamic antral scintigraphy (DAS) for antral contraction rate estimation. The proposed EMD-Fourier method analyzes a DAS time-activity curve (TAC) which is called a DAS signal by estimating the frequency from the Fourier transform of each intrinsic mode function (IMF), thus yielding multiple frequency values for each TAC as opposed to one frequency value obtained from the conventional Fourier method. Twenty-three TACs extracted from DAS data acquired on twenty-three healthy volunteers were analyzed using both the EMD-Fourier method and the Fourier method...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29047974/mean-estimation-empirical-mode-decomposition-method-for-terahertz-time-domain-spectroscopy-de-noising
#13
Xiaoli Qiao, Xinming Zhang, Jiaojiao Ren, Dandan Zhang, Guohua Cao, Lijuan Li
The wavelet-domain de-noising technique has many applications in terahertz time-domain spectroscopy (THz-TDS). However, it requires a complex procedure for the selection of the optimal wavelet basis and threshold, which varies for different materials. Inappropriate selections can lead to de-noising failure. Here, we propose the Mean Estimation Empirical Mode Decomposition (ME-EMD) de-noising method for THz-TDS. First, the THz-TDS signal and the collected reference noise are decomposed into the intrinsic mode functions (IMFs); second, the maximum and mean absolute values of the noise IMF amplitudes are calculated and defined as the adaptive threshold and adaptive estimated noise value, respectively; finally, these thresholds and estimated noise values are utilized to filter the noise from the signal IMFs and reconstruct the THz-TDS signal...
September 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29047886/thermal-conductivity-of-gaas-alas-distributed-bragg-reflectors-in-semiconductor-disk-laser-comparison-of-molecular-dynamics-simulation-and-analytic-methods
#14
Peng Zhang, Maohua Jiang, Renjiang Zhue, Dingke Zhang, Yanrong Song
GaAs/AlAs distributed Bragg reflectors (DBRs) are widely used in the gain chips of 1 μm wave band semiconductor disk lasers (SDLs) as an end/folded cavity mirror. Because the generated redundant heat in the active region of a gain chip mainly dissipates through the DBR, thermal conductivities of DBRs are crucial for the output performance of SDLs. For the purpose of more reasonable semiconductor wafer design, to improve the thermal management of SDLs, accurate thermal conductivities of DBRs with various layer thicknesses are under considerable requirement...
May 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/29044527/effect-of-the-combined-use-of-enamel-matrix-derivative-and-atelocollagen-sponge-scaffold-on-osteoblastic-differentiation-of-mouse-induced-pluripotent-stem-cells-in-vitro
#15
Y Hisanaga, E Suzuki, H Aoki, M Sato, A Saito, A Saito, T Azuma
BACKGROUND AND OBJECTIVE: Induced pluripotent stem cells (iPSCs) are a candidate cell source in periodontal regenerative therapy. Enamel matrix derivative (EMD) has been shown to regenerate periodontal tissues, and atelocollagen sponge (ACS) is considered a suitable scaffold or carrier for growth factors. This study aimed to investigate the effect of combined use of EMD and an ACS scaffold on cell behaviors and differentiation of mouse iPSCs (miPSCs) in vitro. MATERIAL AND METHODS: Following embryonic body formation from miPSCs, dissociated cells (miPS-EB-derived cells) were seeded onto ACS with or without EMD, and cultured in osteoblast differentiation medium...
October 17, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29044359/management-della-retinopatia-diabetica-e-dell-edema-maculare-diabetico-linee-guida-euretina-2017
#16
P Turchetti, A Librando, F Angelucci, S C Carlesimo, R Migliorini
Si prevede che la malattia diabetica con tutte le sue complicanze avrà un forte aumento di incidenza con un grosso impatto socioeconomico nei prossimi decenni in tutto il mondo. Pertanto ben si comprende l'importanza di individuare attraverso una fine diagnostica quanto più precocemente la comparsa dei sintomi diabetici, migliorare lo stile di vita ed impostare cure efficienti. Riportiamo la serie di raccomandazioni EURETINA 2017, dei maggiori esperti in Europa per la gestione della malattia diabetica e delle complicanze della retina...
September 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29041375/automatic-fringe-enhancement-with-novel-bidimensional-sinusoids-assisted-empirical-mode-decomposition
#17
Chenxing Wang, Qian Kemao, Feipeng Da
Fringe-based optical measurement techniques require reliable fringe analysis methods, where empirical mode decomposition (EMD) is an outstanding one due to its ability of analyzing complex signals and the merit of being data-driven. However, two challenging issues hinder the application of EMD in practical measurement. One is the tricky mode mixing problem (MMP), making the decomposed intrinsic mode functions (IMFs) have equivocal physical meaning; the other is the automatic and accurate extraction of the sinusoidal fringe from the IMFs when unpredictable and unavoidable background and noise exist in real measurements...
October 2, 2017: Optics Express
https://www.readbyqxmd.com/read/29032286/difference-or-delay-a-comparison-of-bayley-iii-cognition-item-scores-of-young-children-with-and-without-developmental-disabilities
#18
Linda Visser, Carla Vlaskamp, Cornelius Emde, Selma A J Ruiter, Marieke E Timmerman
The "difference or delay paradigm" focuses on the question of whether children with developmental disabilities (DD) develop in a way that is only delayed, compared to typically developing children, or also qualitatively different. The current study aimed to examine whether qualitative differences exist in cognitive development of young children with and without DD on the basis of item scores on the Dutch Bayley-III Cognition scale. Differential item functioning was identified for 15 of the 91 items. The presence of DD was related to a higher number of Guttman errors, hinting at more deviation in the order of skill development...
October 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29016882/intra-atrial-re-entrant-tachycardia-in-patients-with-congenital-heart-disease-factors-associated-with-disease-severity
#19
Ivo Roca-Luque, Nuria Rivas Gándara, Laura Dos Subirà, Jaume Francisco Pascual, Jordi Pérez-Rodon, Antònia Pijuan Domenech, Ma Teresa Subirana, Berta Miranda, Alba Santos Ortega, Jaume Casaldàliga Ferrer, David García-Dorado García, Angel Moya Mitjans
Aim: Intra-atrial re-entrant tachycardia (IART) is a common complication in patients with congenital heart disease (CHD) and is related to increased morbidity and mortality. Few reports have been published about factors associated to IART severity. The aim of this study is to analyse factors associated to severe clinical presentation of IART. Methods and Results: Observational study of all consecutive CHD patients who underwent a first IART ablation from January 2009 to December 2015 (94 patients, 39...
July 28, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28965367/healing-of-2-wall-intrabony-defects-treated-with-a-novel-emd-liquid-a-preclinical-study-in-monkeys
#20
Yoshinori Shirakata, Richard J Miron, Yukiya Shinohara, Toshiaki Nakamura, Kotaro Sena, Naoto Horai, Dieter D Bosshardt, Kazuyuki Noguchi, Anton Sculean
AIM: To investigate the effect of a novel enamel matrix derivative formulation (EMD-liquid or Osteogain) combined with an absorbable collagen sponge (ACS) on periodontal wound healing in intrabony defects in monkeys. MATERIALS AND METHODS: Chronic 2-wall intrabony defects were created at the distal aspect of 8 teeth in 3 monkeys (Macaca fascicularis). The 24 defects were randomly assigned to one of the following treatments: (1) Open flap debridement (OFD) + ACS alone, (2) OFD + Emdogain + ACS (Emdogain/ACS), (3) OFD + Osteogain + ACS (Osteogain/ACS), or (4) OFD alone...
October 1, 2017: Journal of Clinical Periodontology
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