keyword
MENU ▼
Read by QxMD icon Read
search

Progesterone in pregnancy

keyword
https://www.readbyqxmd.com/read/28431985/quercetin-interferes-with-the-fluid-volume-and-receptivity-development-of-the-uterus-in-rats-during-the-peri-implantation-period
#1
Huma Shahzad, Nelli Giribabu, Kamarulzaman Karim, Normadiah Kassim, Sekaran Muniandy, Kilari Eswar Kumar, Naguib Salleh
HYPOTHESIS: quercetin could induce changes to the fluid volume and receptivity development of the uterus during peri-implantation period. METHODS: Female rats were treated with quercetin (10, 25 and 50mg/kg/day) subcutaneously beginning from day-1 pregnancy. Uterus was harvested at day-4 (following three days quercetin treatment) for morphological, ultra-structural, protein and mRNA expressional changes and plasma sex-steroid levels analyses. In another cohort of rats, implantation rate was determined at day-6 (following five days quercetin treatment)...
April 18, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28431863/the-myometrial-contractility-during-late-pregnancy-in-dairy-cows-in-vitro
#2
L Górriz-Martín, S E Ulbrich, M Schmicke, G Hirsbrunner, C Keller, N Yücesoy, C Pfarrer, H Bollwein, M Heppelmann
This study aimed to investigate the in vitro contractility of the myometrium and its relationship to the blood concentrations of estradiol-17β (E2β), progesterone (P4), 15-keto-13,14-dihydro-PGF2α (PGFM) and ionised calcium (Ca(2+)) prior to tissue harvest in 12 healthy Holstein-Friesian cows in late pregnancy. Three circular (CM) and 3 longitudinal myometrial (LM) strips were dissected during a caesarean section and mounted in an organ bath containing modified Krebs solution (KS). The spontaneous contractility was recorded during five 30-min time periods (T1 to T5), after which the strips were exposed to increasing concentrations of oxytocin (OT; 10(-10)-10(-7)M), a natural PGF2α-analogue (PGF; 10(-7)-10(-4)M) and KS (Cont) for four 30-min time periods (T6 to T9)...
April 7, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28428343/mechanisms-of-autophagy-induction-by-sex-steroids-in-bovine-mammary-epithelial-cells
#3
Katarzyna Zielniok, Agnieszka Sobolewska, Malgorzata Gajewska
In dairy cattle mammary gland involution serves to remodel the secretory tissue, and occurs in a period of overlap between mammogenic stimulation caused by next developing pregnancy and tissue regression induced by milk stasis. At this time high concentrations of 17β-estradiol (E2) and progesterone (P4) support regeneration of the mammary tissue, as well as enhance autophagy, a cellular process induced in response to stressful conditions for energy generation and homeostasis maintenance. This study aimed to elucidate the mechanisms of autophagy induction by E2 and P4 using an in vitro model of involution based on 20-fold reduction of FBS content (from 10% to 0...
April 20, 2017: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/28423605/pregnancy-at-early-age-is-associated-with-a-reduction-of-progesterone-responsive-cells-and-epithelial-wnt-signaling-in-human-breast-tissue
#4
Simone Muenst, Robert Mechera, Silvio Däster, Salvatore Piscuoglio, Charlotte K Y Ng, Fabienne Meier-Abt, Walter P Weber, Savas D Soysal
BACKGROUND: Pregnancy at early age is the most significant modifiable factor which consistently decreases lifetime breast cancer risk. However, the underlying mechanisms haven't been conclusively identified. Studies in mice suggest a reduction in progesterone-receptor (PR) sensitive epithelial cells as well as a downregulation of the Wnt signaling pathway as being one of the main mechanisms for the protective effect of early pregnancy. The aim of our study was to validate these findings in humans...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28420820/high-insulin-impaired-ovarian-function-in-early-pregnant-mice-and-the-role-of-autophagy-in-this-process
#5
Yan Su, Juan Wu, Junlin He, Xueqing Liu, Xuemei Chen, Yubin Ding, Chen Zhang, Wenqi Chen, Yingxiong Wang, Rufei Gao
Metabolic disorders, such as PCOS (polycystic ovarian syndrome) and T2DM (type 2 diabetes mellitus), are associated with menstrual dysfunction, anovulation, infertility, and early pregnancy loss. Ovarian dysfunction is not only related to low pregnancy rates but also to the increased risk of miscarriage. Women with PCOS or T2DM, characterized by hyperinsulinemia, commonly experience ovarian dysfunction. In this study, we first explored whether high insulin levels directly affected ovarian functioning during embryo implantation...
April 18, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28416377/comparison-between-two-estradiol-progesterone-based-protocols-for-timed-artificial-insemination-in-blocks-in-lactating-nelore-cows
#6
L F M Pfeifer, N A Castro, P M A Neves, J P Cestaro, A Schneider
The aim of this study was to compare the use of artificial insemination in time blocks (Artificial Insemination Blocks, AIB) using an 8 and 9 d estradiol-progesterone based protocol. In this experiment, lactating Nelore cows (n=253) were subjected to two estradiol-progesterone based TAI protocols. On the morning of Day 10 (8d group, n=124) or Day 11 (9d group, n=129), cows were examined by ultrasonography to evaluate the diameter of the preovulatory follicle and were inseminated once at one of the following time points, according to the diameter of the pre-ovulatory follicle (POF): Block 0 (POF≥15mm, TAI 0h after conventional TAI), Block 1 (POF 13...
April 4, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28414589/progesterone-decreases-in-vitro-indoleamine-2-3-dioxygenase-expression-in-dendritic-and-cd4-cells-from-maternal-fetal-interface-of-rats
#7
Pedro Kastein Faria da Cunha Bianchi, Rafael Magdanelo Leandro, Aline Nayara Poscai, Tulio Yoshinaga, Patrícia Orlandini Gonçalez, José Roberto Kfoury Junior
PROBLEM: Several mechanisms contribute to the tolerogenic state observed during pregnancy, such as the activity of the enzyme indoleamine 2, 3-dioxygenase (IDO). This initializes the catabolism of tryptophan, inducing T cells to apoptosis due to its deprivation and by the action of its catabolites in the placental microenvironment. Progesterone plays an important part on immunological tolerance mechanisms during pregnancy; however, there is no evidence it is related to IDO activity. Thus, this study aimed to investigate progesterone influence on the maternal-fetal interface of pregnant Wistar rats, by identifying IDO positive cells by immunophenotyping and flow cytometry under exogenous progesterone supplementation...
April 17, 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28412388/prolactin-modulates-luteal-activity-in-the-short-nosed-fruit-bat-cynopterus-sphinx-during-delayed-embryonic-development
#8
Anuradha, Amitabh Krishna
The aim of this study was to evaluate the role of prolactin as a modulator of luteal steroidogenesis during the period of delayed embryonic development in Cynopterus sphinx. A marked decline in circulating prolactin levels was noted during the months of November through December coinciding with the period of decreased serum progesterone and delayed embryonic development. The seasonal changes in serum prolactin levels correlated positively with circulating progesterone (P) level, but inversely with circulating melatonin level during first pregnancy showing delayed development in Cynopterus sphinx...
April 12, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28407856/relationship-between-circulating-progesterone-at-timed-ai-and-fertility-in-dairy-cows-subjected-to-gnrh-based-protocols
#9
M G Colazo, I López Helguera, A Behrouzi, D J Ambrose, R J Mapletoft
The objectives of this retrospective study were: 1) to investigate the effect of plasma progesterone (P4) concentrations at the time of timed-AI (TAI) on fertility, and 2) to examine risk factors associated with plasma P4 concentrations that impair fertility in lactating dairy cows subjected to GnRH-based protocols. Data from 872 lactating Holstein cows that had, or had not been presynchronized prior to a 7-day GnRH-based TAI protocol were examined. However, data from only those cows (n = 697; 79.9%) that ovulated after second GnRH were analyzed...
May 2017: Theriogenology
https://www.readbyqxmd.com/read/28407852/establishment-and-characterization-of-a-telomerase-immortalized-porcine-luteal-cells
#10
Liang Zhang, Yong Huang, Zhenyu Wang, Xiaomao Luo, Hongling Zhang, Qian Du, Lingling Chang, Xiaomin Zhao, Dewen Tong
Luteal cells play a crucial role in pregnancy through secreting progesterone to maintain pregnancy and support of fetus. However, low cellular yields and inability to passage primary porcine luteal cells (PLCs) in vitro limit the luteal cell study. Therefore, developing an immortalized porcine luteal cell line is necessary for studying luteal cells activity and function in different diseases. In this study, primary PLCs were obtained from gilts at day 30 to day 50 of gestation and immortalized by human telomerase reverse transcriptase (hTERT)...
May 2017: Theriogenology
https://www.readbyqxmd.com/read/28407850/association-between-subclinical-hypocalcemia-in-the-first-3-days-of-lactation-and-reproductive-performance-of-dairy-cows
#11
L S Caixeta, P A Ospina, M B Capel, D V Nydam
The objective of this study was to determine the effects of subclinical hypocalcemia on reproductive performance in dairy cows. In a prospective cohort study, 97 cows on 2 dairy farms with automatic milking systems were monitored for subclinical hypocalcemia. Animals were enrolled 7 ± 3 days prior to estimated calving date and three parity groups were defined based on the lactation that the animals were going to start: lactation = 1, lactation = 2, and lactation ≥3. Serum calcium concentration (Ca) was measured in all animals in the first 3 DIM and subclinical hypocalcemia (SCH) was defined as Ca ≤ 8...
May 2017: Theriogenology
https://www.readbyqxmd.com/read/28405121/gnrh-agonist-treatment-improves-implantation-and-pregnancy-rates-of-frozen-thawed-embryos-transfer
#12
S A Hebisha, H M Adel
OBJECTIVE: To study the effect of GnRh agonist administration prior to estrogen-progesterone preparation of the endometrium on the implantation rate in frozen-thawed embryo transfer (FET) cycles in infertile patients treated with IVF/ICSI. DESIGN: Prospective controlled study. SETTING: Private center in Alexandria, Egypt. PATIENTS: Patients undergoing frozen-thawed embryo transfer FET. INTERVENTIONS: Patients were divided into two groups, A and B...
April 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28396044/predictive-factors-influencing-pregnancy-rates-after-intrauterine-insemination-with-frozen-donor-semen-a-prospective-cohort-study
#13
Annelies Thijssen, An Creemers, Wim Van der Elst, Eva Creemers, Eva Vandormael, Nathalie Dhont, Willem Ombelet
The extent to which certain parameters can influence pregnancy rates after intrauterine insemination with frozen donor semen was examined prospectively. Between July 2011 and September 2015, 402 women received 1264 IUI cycles with frozen donor semen in a tertiary referral infertility centre. A case report form was used to collect data prospectively. The primary outcome measure was clinical pregnancy rate (CPR), confirmed by detection of a gestational sac and fetal heartbeat using ultrasonography at 7-8 weeks of gestation...
March 23, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28395330/contributions-to-the-dynamics-of-cervix-remodeling-prior-to-term-and-preterm-birth%C3%A2
#14
Steven M Yellon
Major clinical challenges for obstetricians and neonatologists result from early cervix remodeling and preterm birth. Complications related to cervix remodeling or delivery account for significant morbidity in newborns and peripartum mothers. Understanding morphology and structure of the cervix in pregnant women is limited mostly to the period soon before and after birth. However, evidence in rodent models supports a working hypothesis that a convergence of factors promotes a physiological inflammatory process that degrades the extracellular collagen matrix and enhances biomechanical distensibility of the cervix well before the uterus develops the contractile capabilities for labor...
January 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28390723/manipulation-of-reproductive-seasonality-using-melatonin-implantation-in-anglo-nubian-does-treated-with-controlled-internal-drug-release-and-equine-chorionic-gonadotropin-during-the-nonbreeding-season
#15
M Y El-Mokadem, A N M Nour El-Din, T A Ramadan, A M A Rashad, T A Taha, M A Samak
The objective of this study was to compare the efficiency of hormonal treatments on ovarian activity and reproductive performance in anestrous Anglo-Nubian does during the nonbreeding season (February to May). A total of 48 multiparous does were divided into 2 groups (24 lactating does and 24 dry does). In each group, animals were allocated randomly into 2 equal subgroups (12 does each). In the first subgroup, does received a single 18-mg melatonin implant for 42 d followed by a controlled internal drug release (CIDR) device for 19 d in conjunction with 500 IU of equine chorionic gonadotropin (eCG) i...
April 5, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28381564/the-relationship-between-weight-gain-during-pregnancy-and-allopregnanolone-levels-a-longitudinal-study
#16
Anette Lundqvist, Herbert Sandström, Torbjörn Bäckström
OBJECTIVE: Excessive weight gain during pregnancy poses a risk for negative complications for mother and fetus. Hunger and satiety are regulated in the hypothalamus, where the gamma-amino-butyric acid system (GABA) plays an important role. Allopregnanolone, a progesterone metabolite, increases during pregnancy and is a potent GABA-A receptor modulating steroid. Allopregnanolone has been shown to induce overeating in rodents. The aim of this study was to investigate whether there is a relationship between weight gain and allopregnanolone concentrations during pregnancy in humans...
April 5, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28380577/the-effect-of-follicular-wave-on-fertility-characteristics-in-beef-cattle
#17
A M Muth-Spurlock, J A Dix, M P T Coleson, C G Hart, C O Lemley, T M Schulmeister, G C Lamb, J E Larson
The objectives of this experiment were to determine the effects of follicular wave (first or second) on diameter of the dominant follicle, concentrations of progesterone and estradiol and the hepatic enzymes that inactivate them, thickness of the endometrium, and pregnancy rates to AI. Beef heifers ( = 101) and cows ( = 106) were randomly assigned to 1 of 2 treatments: insemination to the first follicular wave (FFW) or insemination to the second follicular wave (SFW). Estrous cycles of females were synchronized to ensure appropriate timing for the treatments...
February 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28377131/bovine-herpesvirus-1-modified-live-virus-vaccines-for-cattle-reproduction-balancing-protection-with-undesired-effects
#18
Christopher C L Chase, Robert W Fulton, Donal O'Toole, Benjamin Gillette, Russell F Daly, George Perry, Travis Clement
Bovine herpesvirus 1 (BoHV-1) has long been associated with reproductive failure in cattle following infection of the ovary and/or fetus. Vaccination prior to breeding has been an effective approach to lessen the impact of BoHV-1 on reproduction. Prior studies in the 1980s and 1990s established the susceptibility of the ovary and particularly the corpus luteum (CL) to BoHV-1 infection. A series of studies at breeding time established that: (1) in naïve animals, the CL was the major target of BoHV-1 pathology; (2) CL lesions occurred within 4-9 days after estrus; (3) similar lesions was seen with BoHV-1 MLV vaccines; (4) ovarian lesions varied by the vaccine strain used; (5) progesterone decreased with or without CL lesions; and (6) following reactivation of BoHV-1 latent infection, ovaries could become reinfected in the face of BoHV-1 immunity...
March 23, 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28374065/prenatal-exposure-to-progesterone-affects-sexual-orientation-in-humans
#19
June M Reinisch, Erik Lykke Mortensen, Stephanie A Sanders
Prenatal sex hormone levels affect physical and behavioral sexual differentiation in animals and humans. Although prenatal hormones are theorized to influence sexual orientation in humans, evidence is sparse. Sexual orientation variables for 34 prenatally progesterone-exposed subjects (17 males and 17 females) were compared to matched controls (M age = 23.2 years). A case-control double-blind design was used drawing on existing data from the US/Denmark Prenatal Development Project. Index cases were exposed to lutocyclin (bioidentical progesterone = C21H30O2; M W : 314...
April 3, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28373728/pregnancy-per-ai-in-holstein-heifers-inseminated-with-sex-selected-or-conventional-semen-after-estrus-detection-or-timed-ai
#20
Marcos G Colazo, Reuben J Mapletoft
This study compared pregnancy per AI (P/AI) of heifers inseminated with sex-selected or conventional semen after estrus detection (ED) or timed-AI (TAI). Heifers in the ED group received 2 treatments with prostaglandin F2α 14 d apart and those in the TAI group received a modified 5-day Co-synch protocol plus an intravaginal progesterone releasing insert device (PRID) and were inseminated 72 h after PRID removal. Overall P/AI were 69.2% (74/107) and 64.1% (75/117) for conventional and sex-selected semen (P > 0...
April 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
keyword
keyword
113274
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"