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splenectomy in gástric cancer

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https://www.readbyqxmd.com/read/29130233/-clinical-features-and-prognosis-analysis-of-21-gastric-cancer-patients-with-pathological-complete-response-after-neoadjuvant-chemotherapy
#1
Liangqun Peng, Wei Yang, Zhandong Zhang, Hongxing Liu, Yawei Hua
OBJECTIVE: To evaluate the clinical features and prognosis of gastric cancer patients with pathological complete response (pCR) after neoadjuvant chemotherapy (NAC). METHODS: Clinical data of 159 gastric cancer patients who received NAC followed by surgical resection between January 2012 and December 2014 at the Affiliated Tumor Hospital of Zhengzhou University were collected and clinical features of those with pCR were analyzed retrospectively. Kaplan-Meier method was used to estimate 3-year overall survival (OS) rate and recurrence-free survival (RFS) rate...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29123584/analysis-of-postoperative-morbidity-and-mortality-following-surgery-for-gastric-cancer-surgeon-volume-as-the-most-significant-prognostic-factor
#2
Maciej Ciesielski, Wiesław J Kruszewski, Jakub Walczak, Mariusz Szajewski, Jarosław Szefel, Jacek Wydra, Tomasz Buczek, Maksymilian Czerepko
Introduction: Surgical resection is the only potentially curative modality for gastric cancer and it is associated with substantial morbidity and mortality. Aim: To determine risk factors for postoperative morbidity and mortality following major surgery for gastric cancer. Material and methods: Between 1.08.2006 and 30.11.2014 in the Department of Oncological Surgery of Gdynia Oncology Centre 162 patients underwent gastric resection for adenocarcinoma...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29119277/priority-of-lymph-node-dissection-for-proximal-gastric-cancer-invading-the-greater-curvature
#3
Yukio Maezawa, Toru Aoyama, Takanobu Yamada, Kazuki Kano, Tsutomu Hayashi, Tsutomu Sato, Takashi Oshima, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Haruhiko Cho, Takaki Yoshikawa
BACKGROUND: The therapeutic efficacy of dissection of the splenic hilar lymph nodes (#10) has not been fully evaluated in locally advanced proximal gastric cancer (LAGC) invading the greater curvature of the stomach. METHODS: Patients with LAGC invading the greater curvature who underwent D2 total gastrectomy with splenectomy between January 2000 and May 2015 were retrospectively examined. The therapeutic value index was calculated by multiplying the metastatic rate of a station and the 5-year survival of patients with metastasis to that station; the metastatic rate and the index of each lymph node station were then compared...
November 8, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29102948/five-year-survival-after-surgical-removal-and-gamma-knife-stereotactic-radiosurgery-for-a-cerebellar-metastasis-from-an-esophagogastric-junction-cancer-a-case-report-and-literature-review
#4
Yoshikazu Kanazawa, Itsuo Fujita, Daisuke Kakinuma, Yuto Aoki, Hitoshi Kanno, Hiroki Arai, Kunihiko Matsuno, Tomohiro Shimoda, Takeshi Matsutani, Nobutoshi Hagiwara, Tsutomu Nomura, Takeshi Yamada, Shunji Kato, Zenya Naito, Hideaki Takasaki, Eiji Uchida
Brain metastases originating from esophageal or gastric cancer are rare, accounting for 2.1-3.3% of all brain tumors registered in Japan. There are no established therapeutic measures for brain metastases, which accordingly have a poor prognosis. We present here a patient who survived for 5 years after surgery and gamma knife treatment of a cerebellar metastasis from esophagogastric adenocarcinoma. The primary gastric cancer was treated by laparotomy with total gastrectomy, splenectomy, and D2 lymphadenectomy...
November 2017: In Vivo
https://www.readbyqxmd.com/read/28970735/arterioportal-shunt-incidental-to-treatment-with-oxaliplatin-that-mimics-recurrent-gastric-cancer
#5
Hong-Beum Kim, Sang-Gon Park
Arterioportal shunt (APS) is an organic communication between the hepatic arterial system and the portal venous system. The APS is one of the major causes of transient hepatic attenuation differences on dynamic computed tomography (CT) or magnetic resonance imaging (MRI). This condition is usually associated with trauma, liver cirrhosis, and malignancies of the liver. However, there has been no report about oxaliplatin-induced APS. A 41-year-old male was diagnosed with Stage IIIB gastric cancer. The patient initially underwent neoadjuvant chemotherapy with capecitabine and oxaliplatin After 3 cycles of therapy, the mass had markedly decreased, and a total gastrectomy with splenectomy was performed...
September 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28963709/predictors-and-prognostic-implications-of-perioperative-chemotherapy-completion-in-gastric-cancer
#6
Georgios Karagkounis, Malcolm Hart Squires, Marcovalerio Melis, George A Poultsides, David Worhunsky, Linda X Jin, Ryan C Fields, Gaya Spolverato, Timothy M Pawlik, Konstantinos I Votanopoulos, Edward A Levine, Carl Schmidt, Mark Bloomston, Clifford S Cho, Sharon Weber, Antonio Masi, Russell Berman, H Leon Pachter, Charles A Staley, Elliot Newman, Shishir K Maithel, Ioannis Hatzaras
BACKGROUND: Perioperative chemotherapy in gastric cancer is increasingly used since the "MAGIC" trial, while clinical practice data outside of trials remain limited. We sought to evaluate the predictors and prognostic implications of perioperative chemotherapy completion in patients undergoing curative-intent gastrectomy across multiple US institutions. METHODS: Patients who underwent curative-intent resection of gastric adenocarcinoma between 2000 and 2012 in eight institutions of the US Gastric Cancer Collaborative were identified...
September 29, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28953134/national-trends-in-extended-procedures-for-ovarian-cancer-debulking-surgery
#7
Nathaniel L Jones, Ling Chen, Sudeshna Chatterjee, Ana I Tergas, William M Burke, June Y Hou, Cande V Ananth, Alfred I Neugut, Dawn L Hershman, Jason D Wright
OBJECTIVE: Primary cytoreduction for ovarian cancer often requires extended radical procedures and is associated with significant morbidity. In 2010, neoadjuvant chemotherapy was shown to have similar survival to primary cytoreduction but with less need for radical surgery. We hypothesized that the increased use of neoadjuvant chemotherapy would decrease the use of radical cytoreductive procedures and thus examined trends in the performance of radical cytoreductive procedures. METHODS: We used the Nationwide Inpatient Sample to determine the annual number of extended procedures (colon, small intestine, liver, diaphragm, spleen, and gastric resection, ileostomy, colostomy) performed in women undergoing surgery for ovarian cancer from 1998 to 2013...
September 22, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28876422/gastric-cancer-with-lesion-extending-to-spleen-and-perforation-into-free-peritoneum
#8
Roberto Gonçalves, Roberto Saad, Carlos Alberto Malheiros, Paulo Kassab, Nathália Lins Pontes Vieira
Perforated gastric carcinoma is a rare condition that is hard to diagnose preoperatively. It is associated with advanced cancer stages and has a high mortality, particularly in cases presenting preoperative shock. Few studies have investigated the presentation and adequate management of these carcinomas. In addition, there are no reports in the literature on perforations extending to the spleen, as described in this case, making the management of these lesions challenging. Our article reports a case of gastric tumor perforation extending to the spleen, which presented as a perforated acute abdomen...
June 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28851346/metachronous-solitary-splenic-metastasis-arising-from-early-gastric-cancer-a-case-report-and-literature-review
#9
Tsutomu Namikawa, Yasuhiro Kawanishi, Kazune Fujisawa, Eri Munekage, Masaya Munekage, Takahito Sugase, Hiromichi Maeda, Hiroyuki Kitagawa, Tatsuya Kumon, Makoto Hiroi, Michiya Kobayashi, Kazuhiro Hanazaki
BACKGROUND: The metastasis of malignant tumors to the spleen is rare, and only a small percentage of cases can be treated surgically, as splenic metastases generally occur in the context of multivisceral metastatic cancer at a terminal stage. We report a rare case of metachronous solitary splenic metastasis arising from early gastric cancer. CASE PRESENTATION: A 75-year-old man was initially referred to our hospital for examination of gastric cancer, diagnosed at a medical check-up...
August 29, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28842726/laparoscopic-d2-total-gastrectomy-and-en-mass-splenectomy-and-distal-pancreatectomy-for-locally-advanced-proximal-gastric-cancer
#10
Bin Chet Toh, Jaideepraj Rao
BACKGROUND: Safety and efficacy of laparoscopy surgery in locally Advanced Gastric Cancers (AGC) have not been proven by randomized control trials. Therefore, standard of care for AGC is still open surgery. Here, we are presenting a 64-year-old female with proximal gastric adenocarcinoma (close to cardio-oesophageal junction) adherent to tail of pancreas, who underwent D2 total gastrectomy en-mass distal pancreatectomy and splenectomy. METHODS: Five ports are entered into the peritoneal cavity (Three 10-12 mm and two 5 mm ports)...
August 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28836248/-criminal-fold-priority-separating-reduces-splenic-injury-in-laparoscopic-radical-gastrectomy
#11
Wei Wang, Wenjun Xiong, Jin Li, Yansheng Zheng, Lijie Luo, Xiaoyan Hong, Shan'ao Ye, Yuying Wang, Jin Wan
OBJECTIVE: To explore the value of criminal fold priority separating (CFPS) in reduction of iatrogenic splenic injury in laparoscopic radical gastrectomy. METHODS: Complete videos of 270 patients undergoing laparoscopic radical gastrectomy in Guangdong Provincial Hospital of Chinese Medicine were reviewed. Anatomic features of criminal fold (CF) were summarized. The relationship between CFPS and iatrogenic splenic injury was examined. CF was defined as the ligament between omentum and spleen...
August 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28677888/laparoscopic-total-gastrectomy-for-advanced-gastric-cancer-in-a-patient-with-situs-inversus-totalis
#12
Kengo Shibata, Hideki Kawamura, Nobuki Ichikawa, Kazuaki Shibuya, Tadashi Yoshida, Yosuke Ohno, Shigenori Homma, Akinobu Taketomi
Situs inversus totalis (SIT) is a rare congenital anomaly. Generally, laparoscopic surgery is difficult to perform in patients with SIT because of both the potential challenges associated with unexpected vascular anomalies and the lack of standardized strategy for handling such cases. This is the first report of laparoscopic total gastrectomy with lymph node dissection for advanced gastric cancer in a patient with SIT. A 79-year-old man with SIT was diagnosed with advanced gastric cancer. We performed laparoscopic total gastrectomy with modified D2 lymph node dissection (D2 without splenectomy) and esophagojejunal anastomosis using an overlap method involving retrocolic Roux-en-Y reconstruction...
July 5, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28650587/the-value-of-n-staging-with-the-positive-lymph-node-ratio-and-splenectomy-for-remnant-gastric-cancer-a-multicenter-retrospective-study
#13
Sang-Yong Son, Seong-Ho Kong, Hye Seong Ahn, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Do Joong Park, Hyuk-Joon Lee, Hyung-Ho Kim, Han-Kwang Yang
BACKGROUND: Surgery for remnant gastric cancer (RGC) frequently fails to obtain the >15 lymph nodes necessary for tumor-node-metastasis (TNM) staging. We aimed to evaluate the utility of the recently developed tumor-ratio-metastasis (TRM) staging system. We also examined the pattern of lymph node metastasis and the role of prophylactic splenectomy in RGC. METHODS: Between May 2003 and December 2012, data from 170 patients who underwent surgery for RGC were retrospectively analyzed...
June 26, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28637437/curative-resection-by-splenectomy-for-solitary-splenic-metastasis-from-early-gastric-cancer-a-case-report-and-literature-review
#14
Junichi Yoshizawa, Naoki Kubo, Satoshi Ishizone, Fumitoshi Karasawa, Ataru Nakayama
BACKGROUND: Solitary metastasis of a malignancy to the spleen is rare, particularly for gastric cancer. Only a few case reports have documented isolated splenic metastasis from early gastric cancer. We describe a case of splenic metastasis from early gastric cancer. CASE PRESENTATION: A 60-year-old man underwent a distal gastrectomy for early gastric cancer. It infiltrated the submucosa with pathological nodal involvement (pT1bN2M0, stage IIB). One year after the gastrectomy, an abdominal computed tomography scan showed a low-density lesion, 17 mm in diameter, at the upper pole of the spleen...
June 20, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28577727/spleen-preserving-lymphadenectomy-versus-splenectomy-in-laparoscopic-total-gastrectomy-for-advanced-gastric-cancer
#15
Sang-Yong Son, Dong Joon Shin, Young Suk Park, Aung Myint Oo, Do-Hyun Jung, Chang Min Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
BACKGROUND: To investigate the optimal approach for laparoscopic splenic hilum lymph node dissection in proximal advanced gastric cancer, we compared the operative outcomes between laparoscopic spleen-preserving total gastrectomy (sp-LTG) and laparoscopic total gastrectomy with splenectomy (sr-LTG). METHODS: A retrospective case-cohort study was conducted between February 2006 and December 2012. The operative outcomes, the number of retrieved splenic hilum lymph node, complication, and patients' survivals were analyzed...
June 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28545537/efficacy-of-prophylactic-splenectomy-for-proximal-advanced-gastric-cancer-invading-greater-curvature
#16
Yu Ohkura, Shusuke Haruta, Junichi Shindoh, Tsuyoshi Tanaka, Masaki Ueno, Harushi Udagawa
BACKGROUND: For proximal gastric cancer invading the greater curvature, concomitant splenectomy is frequently performed to secure the clearance of lymph node metastases. However, prognostic impact of prophylactic splenectomy remains unclear. The aim of this study was to clarify the oncological significance of prophylactic splenectomy for advanced proximal gastric cancer invading the greater curvature. METHODS: Retrospective review of 108 patients who underwent total or subtotal gastrectomy for advanced proximal gastric cancer involving the greater curvature was performed...
May 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28365893/amylase-concentration-in-drainage-fluid-as-a-predictive-factor-for-severe-postoperative-pancreatic-fistula-in-patients-with-gastric-cancer
#17
Yoshiki Taniguchi, Yukinori Kurokawa, Jota Mikami, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Makoto Yamasaki, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
PURPOSE: Postoperative pancreatic fistula (PPF) sometimes occurs after gastrectomy. We examined the risk factors for severe PPF and evaluated the predictive value of amylase concentration in drainage fluid. METHODS: We retrospectively reviewed 591 patients who underwent curative gastrectomy for gastric cancer. A multivariate analysis was conducted to identify the risk factors for severe PPF. Receiver operating characteristic curves were used to identify the appropriate amylase cut-off value to predict severe PPF...
April 1, 2017: Surgery Today
https://www.readbyqxmd.com/read/28359594/improvement-in-postoperative-mortality-in-elective-gastrectomy-for-gastric-cancer-analysis-of-predictive-factors-in-1066-patients-from-a-single-centre
#18
E Norero, E A Vega, C Diaz, G Cavada, M Ceroni, C Martínez, E Briceño, F Araos, P Gonzalez, S Baez, E Vinuela, M Caracci, A Diaz
BACKGROUND: Gastrectomy represents the main treatment for gastric adenocarcinoma. This procedure is associated with substantial morbidity and mortality. The aim of this study was to evaluate the postoperative mortality changes across the study period and to identify predictive factors of 30-day mortality after elective gastrectomy for gastric cancer. METHODS: This was a retrospective cohort study of a prospective database from a single centre. Patients treated with an elective gastrectomy from 1996 to 2014 for gastric adenocarcinoma were included...
July 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28357085/long-term-survival-and-prognosis-associated-with-conversion-surgery-in-patients-with-metastatic-gastric-cancer
#19
Takahiro Einama, Hironori Abe, Shunsuke Shichi, Hiroki Matsui, Ryo Kanazawa, Kazuaki Shibuya, Takashi Suzuki, Fumihiko Matsuzawa, Taku Hashimoto, Nakachi Kohei, Shigenori Homma, Hideki Kawamura, Akinobu Taketomi
In gastric cancer, primary systemic chemotherapy is the standard approach for the management of patients with initially unresectable metastasis, and it occasionally leads to a reduction in the size of the lesion, which facilitates surgical resection. The aim of this study was to examine the prognosis of patients who were able to undergo complete resection following chemotherapy. A total of 10 patients who underwent radical surgery for stage IV primary gastric cancer after chemotherapy between 2009 and 2015 at the Department of Surgery of Hokkaido Social Work Association Obihiro Hospital (Obihiro, Japan) were retrospectively investigated...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28251018/changing-trends-in-gastric-cancer-surgery
#20
REVIEW
İlter Özer, Erdal Birol Bostancı, Murat Ulaş, Yusuf Özoğul, Musa Akoğlu
Gastric cancer is one of the most common causes of cancer-related death. It requires multimodal treatment and surgery is the most effective treatment modality. Radical surgery includes total or subtotal gastrectomy with lymph node dissection. The extent of lymphadenectomy still remains controversial. Eastern surgeons have performed D2 or more extended lymphadenectomy while their Western colleagues have performed more limited lymph node dissection. However, the trend has been changing in favour of D2 lymph node dissection in both hemispheres...
January 2017: Balkan Medical Journal
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