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splenectomy in gástric cancer

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https://www.readbyqxmd.com/read/28876422/gastric-cancer-with-lesion-extending-to-spleen-and-perforation-into-free-peritoneum
#1
Roberto Gonçalves, Roberto Saad, Carlos Alberto Malheiros, Paulo Kassab, Nathália Lins Pontes Vieira
Perforated gastric carcinoma is a rare condition that is hard to diagnose preoperatively. It is associated with advanced cancer stages and has a high mortality, particularly in cases presenting preoperative shock. Few studies have investigated the presentation and adequate management of these carcinomas. In addition, there are no reports in the literature on perforations extending to the spleen, as described in this case, making the management of these lesions challenging. Our article reports a case of gastric tumor perforation extending to the spleen, which presented as a perforated acute abdomen...
June 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28851346/metachronous-solitary-splenic-metastasis-arising-from-early-gastric-cancer-a-case-report-and-literature-review
#2
Tsutomu Namikawa, Yasuhiro Kawanishi, Kazune Fujisawa, Eri Munekage, Masaya Munekage, Takahito Sugase, Hiromichi Maeda, Hiroyuki Kitagawa, Tatsuya Kumon, Makoto Hiroi, Michiya Kobayashi, Kazuhiro Hanazaki
BACKGROUND: The metastasis of malignant tumors to the spleen is rare, and only a small percentage of cases can be treated surgically, as splenic metastases generally occur in the context of multivisceral metastatic cancer at a terminal stage. We report a rare case of metachronous solitary splenic metastasis arising from early gastric cancer. CASE PRESENTATION: A 75-year-old man was initially referred to our hospital for examination of gastric cancer, diagnosed at a medical check-up...
August 29, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28842726/laparoscopic-d2-total-gastrectomy-and-en-mass-splenectomy-and-distal-pancreatectomy-for-locally-advanced-proximal-gastric-cancer
#3
Bin Chet Toh, Jaideepraj Rao
BACKGROUND: Safety and efficacy of laparoscopy surgery in locally Advanced Gastric Cancers (AGC) have not been proven by randomized control trials. Therefore, standard of care for AGC is still open surgery. Here, we are presenting a 64-year-old female with proximal gastric adenocarcinoma (close to cardio-oesophageal junction) adherent to tail of pancreas, who underwent D2 total gastrectomy en-mass distal pancreatectomy and splenectomy. METHODS: Five ports are entered into the peritoneal cavity (Three 10-12 mm and two 5 mm ports)...
August 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28836248/-criminal-fold-priority-separating-reduces-splenic-injury-in-laparoscopic-radical-gastrectomy
#4
Wei Wang, Wenjun Xiong, Jin Li, Yansheng Zheng, Lijie Luo, Xiaoyan Hong, Shan'ao Ye, Yuying Wang, Jin Wan
OBJECTIVE: To explore the value of criminal fold priority separating (CFPS) in reduction of iatrogenic splenic injury in laparoscopic radical gastrectomy. METHODS: Complete videos of 270 patients undergoing laparoscopic radical gastrectomy in Guangdong Provincial Hospital of Chinese Medicine were reviewed. Anatomic features of criminal fold (CF) were summarized. The relationship between CFPS and iatrogenic splenic injury was examined. CF was defined as the ligament between omentum and spleen...
August 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28677888/laparoscopic-total-gastrectomy-for-advanced-gastric-cancer-in-a-patient-with-situs-inversus-totalis
#5
Kengo Shibata, Hideki Kawamura, Nobuki Ichikawa, Kazuaki Shibuya, Tadashi Yoshida, Yosuke Ohno, Shigenori Homma, Akinobu Taketomi
Situs inversus totalis (SIT) is a rare congenital anomaly. Generally, laparoscopic surgery is difficult to perform in patients with SIT because of both the potential challenges associated with unexpected vascular anomalies and the lack of standardized strategy for handling such cases. This is the first report of laparoscopic total gastrectomy with lymph node dissection for advanced gastric cancer in a patient with SIT. A 79-year-old man with SIT was diagnosed with advanced gastric cancer. We performed laparoscopic total gastrectomy with modified D2 lymph node dissection (D2 without splenectomy) and esophagojejunal anastomosis using an overlap method involving retrocolic Roux-en-Y reconstruction...
July 5, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28650587/the-value-of-n-staging-with-the-positive-lymph-node-ratio-and-splenectomy-for-remnant-gastric-cancer-a-multicenter-retrospective-study
#6
Sang-Yong Son, Seong-Ho Kong, Hye Seong Ahn, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Do Joong Park, Hyuk-Joon Lee, Hyung-Ho Kim, Han-Kwang Yang
BACKGROUND: Surgery for remnant gastric cancer (RGC) frequently fails to obtain the >15 lymph nodes necessary for tumor-node-metastasis (TNM) staging. We aimed to evaluate the utility of the recently developed tumor-ratio-metastasis (TRM) staging system. We also examined the pattern of lymph node metastasis and the role of prophylactic splenectomy in RGC. METHODS: Between May 2003 and December 2012, data from 170 patients who underwent surgery for RGC were retrospectively analyzed...
June 26, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28637437/curative-resection-by-splenectomy-for-solitary-splenic-metastasis-from-early-gastric-cancer-a-case-report-and-literature-review
#7
Junichi Yoshizawa, Naoki Kubo, Satoshi Ishizone, Fumitoshi Karasawa, Ataru Nakayama
BACKGROUND: Solitary metastasis of a malignancy to the spleen is rare, particularly for gastric cancer. Only a few case reports have documented isolated splenic metastasis from early gastric cancer. We describe a case of splenic metastasis from early gastric cancer. CASE PRESENTATION: A 60-year-old man underwent a distal gastrectomy for early gastric cancer. It infiltrated the submucosa with pathological nodal involvement (pT1bN2M0, stage IIB). One year after the gastrectomy, an abdominal computed tomography scan showed a low-density lesion, 17 mm in diameter, at the upper pole of the spleen...
June 20, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28577727/spleen-preserving-lymphadenectomy-versus-splenectomy-in-laparoscopic-total-gastrectomy-for-advanced-gastric-cancer
#8
Sang-Yong Son, Dong Joon Shin, Young Suk Park, Aung Myint Oo, Do-Hyun Jung, Chang Min Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
BACKGROUND: To investigate the optimal approach for laparoscopic splenic hilum lymph node dissection in proximal advanced gastric cancer, we compared the operative outcomes between laparoscopic spleen-preserving total gastrectomy (sp-LTG) and laparoscopic total gastrectomy with splenectomy (sr-LTG). METHODS: A retrospective case-cohort study was conducted between February 2006 and December 2012. The operative outcomes, the number of retrieved splenic hilum lymph node, complication, and patients' survivals were analyzed...
June 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28545537/efficacy-of-prophylactic-splenectomy-for-proximal-advanced-gastric-cancer-invading-greater-curvature
#9
Yu Ohkura, Shusuke Haruta, Junichi Shindoh, Tsuyoshi Tanaka, Masaki Ueno, Harushi Udagawa
BACKGROUND: For proximal gastric cancer invading the greater curvature, concomitant splenectomy is frequently performed to secure the clearance of lymph node metastases. However, prognostic impact of prophylactic splenectomy remains unclear. The aim of this study was to clarify the oncological significance of prophylactic splenectomy for advanced proximal gastric cancer invading the greater curvature. METHODS: Retrospective review of 108 patients who underwent total or subtotal gastrectomy for advanced proximal gastric cancer involving the greater curvature was performed...
May 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28365893/amylase-concentration-in-drainage-fluid-as-a-predictive-factor-for-severe-postoperative-pancreatic-fistula-in-patients-with-gastric-cancer
#10
Yoshiki Taniguchi, Yukinori Kurokawa, Jota Mikami, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Makoto Yamasaki, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
PURPOSE: Postoperative pancreatic fistula (PPF) sometimes occurs after gastrectomy. We examined the risk factors for severe PPF and evaluated the predictive value of amylase concentration in drainage fluid. METHODS: We retrospectively reviewed 591 patients who underwent curative gastrectomy for gastric cancer. A multivariate analysis was conducted to identify the risk factors for severe PPF. Receiver operating characteristic curves were used to identify the appropriate amylase cut-off value to predict severe PPF...
April 1, 2017: Surgery Today
https://www.readbyqxmd.com/read/28359594/improvement-in-postoperative-mortality-in-elective-gastrectomy-for-gastric-cancer-analysis-of-predictive-factors-in-1066-patients-from-a-single-centre
#11
E Norero, E A Vega, C Diaz, G Cavada, M Ceroni, C Martínez, E Briceño, F Araos, P Gonzalez, S Baez, E Vinuela, M Caracci, A Diaz
BACKGROUND: Gastrectomy represents the main treatment for gastric adenocarcinoma. This procedure is associated with substantial morbidity and mortality. The aim of this study was to evaluate the postoperative mortality changes across the study period and to identify predictive factors of 30-day mortality after elective gastrectomy for gastric cancer. METHODS: This was a retrospective cohort study of a prospective database from a single centre. Patients treated with an elective gastrectomy from 1996 to 2014 for gastric adenocarcinoma were included...
July 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28357085/long-term-survival-and-prognosis-associated-with-conversion-surgery-in-patients-with-metastatic-gastric-cancer
#12
Takahiro Einama, Hironori Abe, Shunsuke Shichi, Hiroki Matsui, Ryo Kanazawa, Kazuaki Shibuya, Takashi Suzuki, Fumihiko Matsuzawa, Taku Hashimoto, Nakachi Kohei, Shigenori Homma, Hideki Kawamura, Akinobu Taketomi
In gastric cancer, primary systemic chemotherapy is the standard approach for the management of patients with initially unresectable metastasis, and it occasionally leads to a reduction in the size of the lesion, which facilitates surgical resection. The aim of this study was to examine the prognosis of patients who were able to undergo complete resection following chemotherapy. A total of 10 patients who underwent radical surgery for stage IV primary gastric cancer after chemotherapy between 2009 and 2015 at the Department of Surgery of Hokkaido Social Work Association Obihiro Hospital (Obihiro, Japan) were retrospectively investigated...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28251018/changing-trends-in-gastric-cancer-surgery
#13
REVIEW
İlter Özer, Erdal Birol Bostancı, Murat Ulaş, Yusuf Özoğul, Musa Akoğlu
Gastric cancer is one of the most common causes of cancer-related death. It requires multimodal treatment and surgery is the most effective treatment modality. Radical surgery includes total or subtotal gastrectomy with lymph node dissection. The extent of lymphadenectomy still remains controversial. Eastern surgeons have performed D2 or more extended lymphadenectomy while their Western colleagues have performed more limited lymph node dissection. However, the trend has been changing in favour of D2 lymph node dissection in both hemispheres...
January 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28210017/influence-of-prognostic-factors-for-recurrence-of-adenocarcinoma-of-the-stomach
#14
Indira Mehmedagic, Sefik Hasukic, Mirha Agic, Nedzad Kadric, Ismar Hasukic
INTRODUCTION: Gastric cancer is the second most important neoplasm in the world. Surgical resection is the treatment of choice for gastric cancer, and recognized by the International Union against Cancer (International Union Against Cancer - UICC) TNM classification of the parameters of the tumor and lymph node. Prognostic factors related to characteristics of the tumor by histopathologic findings have an impact on the planning of the operation. According to the results of most studies it is possible to predict survival and recurrence based on histological type and TNM classification of tumors on the one hand and the surgical procedure on the other...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28133264/-resection-of-pancreatic-metastasis-from-renal-cell-carcinoma-21-years-after-nephrectomy
#15
REVIEW
Tomiyuki Miura, Noriaki Nakamura, Kousuke Ogawa, Yuichiro Watanabe, Kouji Yonekura, Takahiro Sanada, Hiroshi Kuwabara, Narihide Goseki
We report a case where resection was performed for pancreatic metastasis from renal cell carcinoma 21 years after nephrectomy. A 72-year-old man had undergone total gastrectomy with distal pancreatomy and splenectomy for gastric cancer, and right nephrectomy for primary renal cell carcinoma in 1993. Incidentally, a CT scan performed in 2014 revealed a tumor in the head of the pancreas. Enhanced MRI suggested that the tumor contained some fat tissue. The tumor in the pancreatic body had sharp margins; therefore, we performed subtotal pancreatectomy...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133185/-surgical-resection-for-advanced-gastric-cancer-with-portal-vein-tumor-embolus-two-cases
#16
Hiroshi Noro, Yoshikazu Morimoto, Shohei Takaichi, Chihyon Son, Kazuya Iwamoto, Emiko Kono, Keigo Yasumasa, Takafumi Hirao, Hitoshi Mizuno, Nobutaka Hatanaka, Yoshio Yamasaki
Gastric cancer with portal tumor embolus is rare and there is no definite strategy for its surgical resection. We report 2 cases ofgastric cancer with portal vein tumor embolus treated using gastrectomy and thrombectomy. Case 1: The patient was a 56- year-old man. We performed total gastrectomy, distal pancreatectomy, splenectomy, and thrombectomy. The patient was treated with 4 courses ofS -1 plus CDDP chemotherapy followed by S-1 administration. Eight months after surgery, CT revealed metastasis in the left adrenal gland and he died 2 years after surgery...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133172/-a-case-of-stage-iv-gastric-cancer-successfully-treated-using-salvage-surgery-after-s-1-cddp-therapy
#17
Yuko Shimada, Tsutomu Hayashi, Keisuke Minamizawa, Taisuke Shibuya, Daiji Nemoto, Hideto Yokoi, Tomoko Wada, Takuo Watanabe, Ryo Takagawa, Hitoshi Murakami, Seiji Hasegawa, Tadao Fukushima, Hideyuki Ike, Yasushi Rino, Munetaka Masuda
A 75-year-old man admitted for left lateral abdominal pain was found to have advanced poorly differentiated gastric adenocarcinoma with abdominal para-aortic and Virchow's lymph node metastases, which was diagnosed to be clinical Stage IV (T3N3H0M1[LYM]). As curative surgery was not deemed possible, we started chemotherapy administration using S-1 (120mg/day)administered orally for 3 weeks and cisplatin(CDDP 100mg/body)administered intravenously on day 8. After 6 courses of chemotherapy, a CT scan showed that all lymph nodes metastases had disappeared, resulting in downstaging to clinical Stage II (T3[SE]N0H0P0M0)...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27928796/-current-status-of-surgical-treatment-of-gastric-gastrointestinal-tumors-a-national-multi-center-retrospective-study
#18
Xingyu Feng, Renjie Li, Peng Zhang, Tao Chen, Haibo Qiu, Yongjian Zhou, Chunyan Du, Xiaonan Yin, Fang Pan, Guoliang Zheng, Xiaowei Sun, Jiang Yu, Zhijing Chen, Yan Zhao, Xiufeng Liu, Jian Li, Bo Zhang, Ye Zhou, Changming Huang, Zhiwei Zhou, Guoxin Li, Kaixiong Tao, Yong Li
OBJECTIVE: To retrospectively analyze the clinicopathology of patients with gastric gastrointestinal stromal tumor(gGIST) who underwent radical excision within 18 years in 10 domestic medical centers in order to understand the status of domestic surgical treatment of gGIST. METHODS: Clinicopathological data of gGIST patients undergoing radical excision in 10 medical centers from January 1998 to January 2016 were collected, and their operational conditions, postoperative adjuvant therapy, gene detection and survival were analyzed retrospectively...
November 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27846844/a-rare-case-with-synchronous-gastric-gastrointestinal-stromal-tumor-pancreatic-neuroendocrine-tumor-and-uterine-leiomyoma
#19
Elena Arabadzhieva, Atanas Yonkov, Sasho Bonev, Dimitar Bulanov, Ivanka Taneva, Alexandrina Vlahova, Tihomir Dikov, Violeta Dimitrova
BACKGROUND: Although gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, they comprise less than 1% of all gastrointestinal tumors. Neuroendocrine tumors (NET) of the gastro-enteropancreatic system are also rare, representing about 2% of all gastrointestinal neoplasms. Pancreatic localization of NET is extremely uncommon-these tumors are only 1-5% of all pancreatic cancers. CASE PRESENTATION: We describe an unusual case with triple tumor localization-a gastric tumor, a formation in the pancreas, which involves the retroperitoneal space, and a uterine leiomyoma...
November 15, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27816984/effect-of-splenectomy-combined-with-resection-for-gastric-carcinoma-on-patient-prognosis
#20
Dun Pan, Hui Chen, Liang-Qing Li, Zong-Fang Li
BACKGROUND For patients with stage IV gastric cancer, it is unclear whether splenectomy combined with palliative surgery is needed to reduce tumor load and relieve symptoms. The objective of the present study was to investigate the effect of splenectomy combined with palliative resection for stage IV gastric carcinoma on immunological dysfunction and patient prognosis. MATERIAL AND METHODS We retrospectively analyzed medical records of 106 stage IV gastric cancer patients who underwent palliative surgery; of these, 49 patients were treated with palliative resection for gastric carcinoma combined with splenectomy, while the other 57 patients retained their spleens...
November 6, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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