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splenectomy in gástric cancer

Y H M Claassen, H H Hartgrink, J L Dikken, W O de Steur, J W van Sandick, N C T van Grieken, A Cats, A K Trip, E P M Jansen, W M Meershoek-Klein Kranenbarg, J P B M Braak, H Putter, M I van Berge Henegouwen, M Verheij, C J H van de Velde
BACKGROUND: In order to determine the optimal combination of perioperative chemotherapy and chemoradiotherapy for Western patients with advanced resectable gastric cancer, the international multicentre CRITICS trial (ChemoRadiotherapy after Induction chemotherapy In Cancer of the Stomach) was initiated. In this trial, patients with resectable gastric cancer were randomised before start of treatment between adjuvant chemotherapy or adjuvant chemoradiotherapy following neoadjuvant chemotherapy plus gastric cancer resection...
February 9, 2018: European Journal of Surgical Oncology
Jinjie Zhang, Jie Wang, Wenqing Hu
In recent years, the incidence of gastric cancer has shown a decreasing trend. However, the incidence of advanced upper gastric cancer in China is steadily increasing. Nowadays, surgery is the only way to cure advanced gastric cancer, and lymph node dissection is the key of operation. Since lymph node metastasis is the main metastatic route of gastric cancer, it is critical for surgeons to be aware of this when performing lymph node dissection during operation. At present, the only possible cure for advanced gastric cancer is surgery...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Ruizeng Dong, Zewei Zhang, Yiming Zhou, Yonghong Hua, Jianmin Guo
OBJECTIVE: To explore the surgical treatment and prognosis of Borrmann type IIII( gastric cancer involving the whole stomach. METHODS: Clinicopathological characteristics and survival data of 223 patients with Borrmann type IIII( gastric cancer involving the whole stomach (defined as the tumor infiltrating 3 regions of the stomach) receiving surgical treatment at the Department of Abdominal Surgery of Zhejiang Cancer Hospital between January 2002 and December 2015 were analyzed retrospectively...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Fenglin Liu, Xinyu Qin
Many retrospective and cohort studies have shown that laparoscopic total gastrectomy(LTG) has advantages of less trauma, quicker recovery and better incision than open total gastrectomy, and is not inferior to laparotomy in safety and the short- and long-term outcomes, so it has been widely applied. However there is still a lack of high level evidence-based basis. At present, several prospective multicenter clinical studies are being carried out in China, Japan and South Korea which have high incidence of gastric cancer to demonstrate the safety and feasibility of LTG and evaluate its long-term outcomes as well...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Kenta Iguchi, Chikara Kunisaki, Sho Sato, Yusaku Tanaka, Hiroshi Miyamoto, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo, Yasushi Rino, Munetaka Masuda
BACKGROUND/AIM: The purpose of this study was to reveal the optimal lymph node (LN) dissection in remnant gastric cancer (RGC) patients. PATIENTS AND METHODS: We retrospectively analyzed 46 RGC patients divided into two groups: patients who underwent initial gastrectomy for benign (group B) and malignant (group M) diseases. RESULTS: Metastasis was more frequently observed at the left (nos. 2, 4sa, 4sb, 10, and 11p/d) and right (nos. 1, 3, 4d, 7, 8a, and 12a) side LNs of RGC in groups M and B...
March 2018: Anticancer Research
Duarte Rego, Paulo Almeida, Paulo Soares, Rui Almeida
INTRODUCTION: Celiac artery (CA) occlusions/stenosis are infrequently associated with liver ischemia due to its unique vascularization where portal vein provides about 75% of liver's perfusion. Collateral flow from gastroduodenal artery also provides, in most cases, enough blood supply to prevent ischemic hepatitis. In cases where these collateral pathways are compromised severe liver ischemia can occur. METHODS: We present a case of acute mesenteric ischemia following gastric surgery that was treated with a hybrid retrograde CA stenting...
February 15, 2018: Annals of Vascular Surgery
Kei Hosoda, Keishi Yamashita, Harukazu Tsuruta, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Marie Washio, Masahiko Watanabe
Globally, the incidence of esophago-gastric junction (EGJ) cancer is rapidly increasing. However, the proposed strategies for the treatment of these types of cancer are so diverse that there is no established consensus on the optimal treatment. The aim of the present study was to identify independent prognostic factors to delineate the optimal strategies for the treatment of EGJ cancer. The medical records of 150 patients with EGJ cancer who underwent curative surgery at the Kitasato University were retrospectively reviewed...
January 2018: Oncology Letters
Riki Asakura, Kentaro Kawasaki, Taisuke Okawa, Hiroki Sakamoto, Takahisa Akashi, Yu Asakura, Yoshiyuki Owada, Seiji Haze, Tetsuya Ienaga, Yoshihiro Ikura, Yasuhiro Iwai
A man in his 60s was admitted to our hospital with anemia. An endoscopic examination revealed advanced gastric cancer. CT revealed peri-gastric and para-aortic lymphadenopathy, and a nodular shadow(20mm)in the lower lobe of the right lung. PET-CT revealed abnormal uptake in the para-aortic lymph node and stomach wall and the nodular shadow in the right lung. A bronchoscopy revealed pulmonary adenocarcinoma. From the above, he was diagnosed with gastric cancer(cT4a, cN2, cM1, cStage IV )and lung cancer(cT2a, cN0, cM0, cStage I B)...
January 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Takeomi Hamada, Atsushi Nanashima, Masahide Hiyoshi, Makoto Ikenoue, Naoya Imamura, Koichi Yano, Yoshiro Fujii, Yoshimasa Kubota, Tesshin Ban, Hiroshi Kawakami, Yuichiro Sato
INTRODUCTION: This is a case report on the advances in preoperative endoscopic-guided fine-needle-aspiration (FNA) diagnosis for pancreatic carcinoma to achieve a curative operation even in patients who have a history of total gastrectomy. CASE PRESENTATION: A 65-year-old man, who underwent total gastrectomy for gastric cancer 13 years ago, had discomfort in the left lateral abdomen. A 3-cm hypovascular mass accompanying a large distal pseudocyst in the pancreatic tail was observed on computed tomography...
January 8, 2018: International Journal of Surgery Case Reports
Ioannis T Konstantinidis, Zeljka Jutric, Oliver S Eng, Susanne G Warner, Laleh G Melstrom, Yuman Fong, Byrne Lee, Gagandeep Singh
BACKGROUND: Robotic total pancreatectomy (TP) represents a minimally invasive approach to a major intra-abdominal operation. Its utility, technique, and outcomes are evolving. METHODS: In this video, we describe a systematic approach to a robotic total pancreatectomy performed for multifocal intraductal papillary mucinous neoplasm (IPMN). Additionally, we reviewed the National Cancer Database (NCDB) to examine the outcomes of robotic TP compared to laparoscopic and open TP between 2010 and 2014...
December 22, 2017: Surgical Endoscopy
Kenichiro Furukawa, Yutaka Tanizawa, Kimihide Kusafuka, Noriyuki Nishiwaki, Keiichi Fujiya, Hayato Omori, Sanae Kaji, Makoto Hikage, Rie Makuuchi, Tomoyuki Irino, Masanori Tokunaga, Etsuro Bando, Taiichi Kawamura, Masanori Terashima
BACKGROUND: Amputation neuromas (ANs) are reactive hyperplasia of nerve tissues that occur after a trauma or surgery involving the peripheral nerves. Only two previous reports of ANs occurring around the stomach and post gastrectomy have been reported. We report the case of a patient with AN near the remnant stomach who underwent distal gastrectomy for gastric cancer. CASE PRESENTATION: A 76-year-old man underwent distal gastrectomy, D1+ lymphadenectomy, and Billroth-I reconstruction for early gastric cancer in another hospital at 63 years of age...
December 12, 2017: Surgical Case Reports
Shimpei Maruoka, Toshiyasu Ojima, Mikihito Nakamori, Masaki Nakamura, Keiji Hayata, Masahiro Katsuda, Toshiaki Tsuji, Hiroki Yamaue
Safe preservation of the remnant stomach during distal gastrectomy in patients who have undergone distal pancreatectomy is important. During distal pancreatectomy, the splenic artery that supplies arterial blood to the cardiac part of stomach is resected. Previous reports suggested that blood flow to the remnant stomach may be insufficient when supplied by only the left inferior phrenic artery. In the present case, a 79-year-old woman who underwent distal pancreatectomy with splenectomy 20 years before she was diagnosed with gastric cancer and referred to our hospital...
December 6, 2017: Asian Journal of Endoscopic Surgery
Liangqun Peng, Wei Yang, Zhandong Zhang, Hongxing Liu, Yawei Hua
OBJECTIVE: To evaluate the clinical features and prognosis of gastric cancer patients with pathological complete response (pCR) after neoadjuvant chemotherapy (NAC). METHODS: Clinical data of 159 gastric cancer patients who received NAC followed by surgical resection between January 2012 and December 2014 at the Affiliated Tumor Hospital of Zhengzhou University were collected and clinical features of those with pCR were analyzed retrospectively. Kaplan-Meier method was used to estimate 3-year overall survival (OS) rate and recurrence-free survival (RFS) rate...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Maciej Ciesielski, Wiesław J Kruszewski, Jakub Walczak, Mariusz Szajewski, Jarosław Szefel, Jacek Wydra, Tomasz Buczek, Maksymilian Czerepko
Introduction: Surgical resection is the only potentially curative modality for gastric cancer and it is associated with substantial morbidity and mortality. Aim: To determine risk factors for postoperative morbidity and mortality following major surgery for gastric cancer. Material and methods: Between 1.08.2006 and 30.11.2014 in the Department of Oncological Surgery of Gdynia Oncology Centre 162 patients underwent gastric resection for adenocarcinoma...
2017: Przegla̜d Gastroenterologiczny
Yukio Maezawa, Toru Aoyama, Takanobu Yamada, Kazuki Kano, Tsutomu Hayashi, Tsutomu Sato, Takashi Oshima, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Haruhiko Cho, Takaki Yoshikawa
BACKGROUND: The therapeutic efficacy of dissection of the splenic hilar lymph nodes (#10) has not been fully evaluated in locally advanced proximal gastric cancer (LAGC) invading the greater curvature of the stomach. METHODS: Patients with LAGC invading the greater curvature who underwent D2 total gastrectomy with splenectomy between January 2000 and May 2015 were retrospectively examined. The therapeutic value index was calculated by multiplying the metastatic rate of a station and the 5-year survival of patients with metastasis to that station; the metastatic rate and the index of each lymph node station were then compared...
November 8, 2017: Gastric Cancer
Yoshikazu Kanazawa, Itsuo Fujita, Daisuke Kakinuma, Yuto Aoki, Hitoshi Kanno, Hiroki Arai, Kunihiko Matsuno, Tomohiro Shimoda, Takeshi Matsutani, Nobutoshi Hagiwara, Tsutomu Nomura, Takeshi Yamada, Shunji Kato, Zenya Naito, Hideaki Takasaki, Eiji Uchida
Brain metastases originating from esophageal or gastric cancer are rare, accounting for 2.1-3.3% of all brain tumors registered in Japan. There are no established therapeutic measures for brain metastases, which accordingly have a poor prognosis. We present here a patient who survived for 5 years after surgery and gamma knife treatment of a cerebellar metastasis from esophagogastric adenocarcinoma. The primary gastric cancer was treated by laparotomy with total gastrectomy, splenectomy, and D2 lymphadenectomy...
November 2017: In Vivo
Hong-Beum Kim, Sang-Gon Park
Arterioportal shunt (APS) is an organic communication between the hepatic arterial system and the portal venous system. The APS is one of the major causes of transient hepatic attenuation differences on dynamic computed tomography (CT) or magnetic resonance imaging (MRI). This condition is usually associated with trauma, liver cirrhosis, and malignancies of the liver. However, there has been no report about oxaliplatin-induced APS. A 41-year-old male was diagnosed with Stage IIIB gastric cancer. The patient initially underwent neoadjuvant chemotherapy with capecitabine and oxaliplatin After 3 cycles of therapy, the mass had markedly decreased, and a total gastrectomy with splenectomy was performed...
September 7, 2017: World Journal of Gastroenterology: WJG
Georgios Karagkounis, Malcolm Hart Squires, Marcovalerio Melis, George A Poultsides, David Worhunsky, Linda X Jin, Ryan C Fields, Gaya Spolverato, Timothy M Pawlik, Konstantinos I Votanopoulos, Edward A Levine, Carl Schmidt, Mark Bloomston, Clifford S Cho, Sharon Weber, Antonio Masi, Russell Berman, H Leon Pachter, Charles A Staley, Elliot Newman, Shishir K Maithel, Ioannis Hatzaras
BACKGROUND: Perioperative chemotherapy in gastric cancer is increasingly used since the "MAGIC" trial, while clinical practice data outside of trials remain limited. We sought to evaluate the predictors and prognostic implications of perioperative chemotherapy completion in patients undergoing curative-intent gastrectomy across multiple US institutions. METHODS: Patients who underwent curative-intent resection of gastric adenocarcinoma between 2000 and 2012 in eight institutions of the US Gastric Cancer Collaborative were identified...
December 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Nathaniel L Jones, Ling Chen, Sudeshna Chatterjee, Ana I Tergas, William M Burke, June Y Hou, Cande V Ananth, Alfred I Neugut, Dawn L Hershman, Jason D Wright
OBJECTIVE: Primary cytoreduction for ovarian cancer often requires extended radical procedures and is associated with significant morbidity. In 2010, neoadjuvant chemotherapy was shown to have similar survival to primary cytoreduction but with less need for radical surgery. We hypothesized that the increased use of neoadjuvant chemotherapy would decrease the use of radical cytoreductive procedures and thus examined trends in the performance of radical cytoreductive procedures. METHODS: We used the Nationwide Inpatient Sample to determine the annual number of extended procedures (colon, small intestine, liver, diaphragm, spleen, and gastric resection, ileostomy, colostomy) performed in women undergoing surgery for ovarian cancer from 1998 to 2013...
September 22, 2017: International Journal of Gynecological Cancer
Roberto Gonçalves, Roberto Saad, Carlos Alberto Malheiros, Paulo Kassab, Nathália Lins Pontes Vieira
Perforated gastric carcinoma is a rare condition that is hard to diagnose preoperatively. It is associated with advanced cancer stages and has a high mortality, particularly in cases presenting preoperative shock. Few studies have investigated the presentation and adequate management of these carcinomas. In addition, there are no reports in the literature on perforations extending to the spleen, as described in this case, making the management of these lesions challenging. Our article reports a case of gastric tumor perforation extending to the spleen, which presented as a perforated acute abdomen...
June 2017: Revista da Associação Médica Brasileira
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