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Josef Finsterer, Ernst Sehnal
Recent data indicate that in patients with hereditary hemorrhagic teleangiectasia (HHT), low iron levels due to inadequate replacement after hemorrhagic iron losses are associated with elevated factor-VIII plasma levels and consecutively increased risk of venous thrombo-embolism. Here, we report a patient with HHT, low iron levels, elevated factor-VIII, and recurrent venous thrombo-embolism. A 64-year-old multimorbid Serbian gipsy was diagnosed with HHT at age 62 years. He had a history of recurrent epistaxis, teleangiectasias on the lips, renal and pulmonary arterio-venous malformations, and a family history positive for HHT...
July 2015: Journal of Neurosciences in Rural Practice
Justyna Przybyszewska, Ewa Żekanowska
INTRODUCTION AND OBJECTIVE: The clinical consequences of malnutrition are multi-directional and result in dysfunctions of the majority of internal organs and systems. The results of recent studies suggest that a significant role is played by malnutrition in pathophysiology of iron homeostasis disorders, but the underlying mechanism is unclear. The study describes the potential role of hepcidin and hemojuvelin in the pathogenesis of disorders of iron metabolism during malnutrition. STATE OF KNOWLEDGE: The participation of hepcidin in regulating iron homeostasis encompasses inhibiting the absorption of food iron from enterocytes and inhibiting the release of stored iron from the reticuloendothelial system cells...
2014: Annals of Agricultural and Environmental Medicine: AAEM
Zoran Leković, Nedeljko Radlović, Radivoj Brdar, Biljana Vuletić, Nenad Janić, Dragana Ristić, Zorica Stojsić, Vladimir Radlović, Dusica Simić, Dejan Nikolić
INTRODUCTION: Idiopathic ulcerative colitis (IUC) represents a rare disease of childhood. It usually occurs at age over 10 years, and below that exceptionally rarely. OBJECTIVE: The aim of the paper was to analyze the clinical signs, symptoms and therapeutic procedures in children with IUC. METHODS: The aims of the paper were based on a sample of 17 children (11 male and 6 female, mean age 11.90 +/- 3.50 years; range 3.8-17.5 years) with IUC...
March 2011: Srpski Arhiv za Celokupno Lekarstvo
Saleh M Abdullah
BACKGROUND: Regular blood donation can lead to iron deficiency. Screening donors' serum ferritin levels at the time of first donation and subsequently once every year is a very rational way to pick up iron deficiency in a voluntary blood donor population. The aim of this study was to determine the effect of blood donation and the prevalence of erythropoiesis with iron deficiency (sideropenia) in Saudi male blood donors. MATERIALS AND METHODS: The study was prospectively conducted, between December 2008 and March 2009, on 182 male native Saudi blood donors at King Fahd Central Hospital in Jazan region, Saudi Arabia...
April 2011: Blood Transfusion, Trasfusione del Sangue
Aldo Morrone, Lorenzo Nosotti, Laura Piombo, Paola Scardella, Raffaella Spada, Alessio Pitidis
BACKGROUND: Martial deficiency and sideropenic anaemia are the most diffused deficiency pathologies in the world. WHO recommends preventive screening of the new immigrant population. No epidemiological data exist on its prevalence among migrant population in Italy. METHODS: A transversal study was conducted at San Gallicano Hospital in Rome through laboratory screening on 821 migrant women and interviews on a sub-sample of 550 women (including socio-demographic, anamnestic and nutritional information)...
April 2012: European Journal of Public Health
Momcilo Pavlović, Nedeljko Radlović, Zoran Leković, Karolina Berenji, Zorica Stojsić, Vladimir Radlović
INTRODUCTION: Coeliac disease (CD) is a permanent intolerance of gluten, i.e., of gliadin and related proteins found in the endosperm of wheat, rye and barley. It is characterized by polygenic predisposition, autoimmune nature, predominantly asymptomatic or atypical clinical course, as well as by high prevalence in patients with Down's syndrome (DS) and some other diseases. OUTLINE OF CASES: We are presenting a girl and two boys, aged 6-7 (x = 6.33) years with DS and CD recognized under the feature of sideropenic anaemia resistant to oral therapy with iron...
January 2010: Srpski Arhiv za Celokupno Lekarstvo
B Palmieri, F Pollastri, M Scafati
This is a review of the most relevant articles on the vitamin C-based therapy with emphasis to high per os and parenteral doses that might be effective on calories utilization, energy production, mythocondrial red-ox function, gene expression and metabolism. Ascorbic acid treatment in tumor bearing patients is a puzzling issue whose rationale is based on low vitamin plasma concentration and cancer uptake and sequestration; furthermore high parenteral dosages should be required to achieve a putative oxidative damage on tumor DNA, by this antioxidant molecule; thus bioavailability and metabolism as well as clinical effectiveness are reviewed on the basis of the evidence based medicine: specific evidence of vitamin C efficacy is quite limited, but areas like diabetic vascular complications and sideropenia might benefit of the treatment; high parenteral doses might be useful, perspectively also in relapsing urinary tract infection, after conventional treatment failure, due to the high output of ascorbic acid and potential saturation of the target tissues...
October 2006: Minerva Medica
Halina Kempa, Jadwiga Sadlak-Nowicka, Anna Kedzia, Paweł Staroń
UNLABELLED: Frequency of occurrence of mycotic infections of the oral mucosa is higher in later years. It is connected with common use of antibiotics, intensive cancer treatment (cytostatics, radiation therapy) as well as immunosuppressant drugs and antibiotics, which have an influence on mikroflora disorders of the oral cavity. Candidiasis of oral mucosa occurs in old patients, in people suffering from diabetes mellitus, hypothyreosis, sideropenia, hypovitaminosis and xerostomia, which is often caused by hypofunction of salivary glands during autoimmune diseases and/or drug and systemic treatment...
2006: Przegla̧d Lekarski
Tamás Zágoni, Ferenc Sipos, Zsolt Tarján, Zoltán Péter
Systemic disease can produce changes in the nails. Perhaps the best known example of this is koilonychia as a sequale of iron deficiency anemia. "Half and half nail" is a type of pseudoleuconychia that can be caused by chronic renal disease, Kawasaki's disease, cirrhosis, and zinc deficiency. It has not been described in patients with Crohn's disease yet. Four male patients with Crohn's disease were observed. None of them had extraintestinal manifestations of Crohn's disease. The average duration of the disease was 5...
July 2006: Diseases of the Colon and Rectum
Fikret Demirci, M Cemil Savaş, Necip Kepkep, Vahap Okan, Mehmet Yilmaz, Mehmet Büyükberber, M Taner Gülşen
Plummer-Vinson syndrome is known as the association of postcricoid dysphagia, upper esophageal web, and iron deficiency anemia. Although correction of iron deficiency may result in resolution of dysphagia and sometimes disappearance of the webs, dilation therapy is usually necessary to remove webs and relieve dysphagia. We report two cases of Plummer-Vinson syndrome. Both patients presented with significant and longstanding dysphagia, sideropenia, glossitis and koilonychia. Our two patients had occasional choking and aspiration episodes at eating and endoscope did not pass through at the level of the upper esophagus...
December 2005: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
P Vicinanza, L Catalano, G Pollio, M Vicinanza, P Di Chiara, M Buonanno, A De Renzo, B Rotoli
Reticulocyte hemoglobin content (CHr) is considered an index of iron status, helpful in the differential diagnosis of microcytoses. Its potential can be enhanced by comparing CHr dynamic reference values (CHr-e: expected CHr), which are proportional to the MCVr variations occurring in micro- or macrocytosis, with measured CHr values. We demonstrate that the difference between measured CHr and CHr-e (DeltaCHr) is helpful to differentiate the anemic syndromes and, in particular, beta-thalassemia vs. presumable sideropenia...
August 2005: Clinical and Laboratory Haematology
Chaim Hershko, Amnon Lahad, Dan Kereth
There has been an increasing awareness recently of subtle, non-bleeding gastrointestinal conditions that may result in abnormal iron absorption leading to iron-deficiency anaemia (IDA) in the absence of gastrointestinal symptoms. Thus, the importance of coeliac disease as a possible cause of IDA refractory to oral iron treatment, without other manifestations of malabsorption syndrome, is increasingly being recognized. In addition, Helicobacter pylori has been implicated in several recent studies as a cause of IDA refractory to oral iron treatment, and the anaemia responds favourably to H...
June 2005: Best Practice & Research. Clinical Haematology
Alicja Hubalewska-Hoła, Anna Sowa-Staszczak, Tomasz Szczerbiński, Grzegorz Lis, Bohdan Huszno, Zbigniew Szybiński
Protein losing enteropathy (PLE) is a gastrointestinal disorder that is associated with excessive loss of plasma protein into the gut resulting from abnormal mucosal permeability. The disease is usually caused by inflammation. The loss of protein in PLE is a nonselective process affecting albumin, globulin and transferrin. Abdominal scintigraphy with human serum albumin marked by Tc99m seems to be an easy and sensitive method for diagnosing PLE. An 4-year-old girl was presented to an outside Pediatric Department due to hypoproteinemia and recurrent pneumonia which had caused several prior hospitalizations...
2003: Przegla̧d Lekarski
No abstract text is available yet for this article.
October 1954: Il Lattante
No abstract text is available yet for this article.
June 25, 1964: Nordisk Medicin
No abstract text is available yet for this article.
March 1964: American Journal of Tropical Medicine and Hygiene
No abstract text is available yet for this article.
1962: Le Poumon et le Coeur
No abstract text is available yet for this article.
February 1962: Revue Française D'études Cliniques et Biologiques
No abstract text is available yet for this article.
February 9, 1962: Münchener Medizinische Wochenschrift
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