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https://www.readbyqxmd.com/read/27734303/brain-injury-after-moderate-drowning-subtle-alterations-detected-by-functional-magnetic-resonance-imaging
#1
Mariana P Nucci, Katerina Lukasova, João R Sato, Edson Amaro
To describe cerebral (structural and functional MRI) and neuropsychological long term changes in moderate drowning victim's compared to healthy volunteers in working memory and motor domains. We studied 15 adult drowning victim's in chronic stage (DV - out of 157 eligible cases of sea water rescues with moderate drowning classification) paired to 18 healthy controls (HC). All participants were investigated using intelligence, memory, and attention neuropsychological standard tests and underwent functional (motor and working memory tasks) and structural magnetic resonance imaging (MRI) in a 3 T system...
October 12, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/25701410/pelvic-magnetic-resonance-imaging-angioanatomy-of-the-arterial-blood-supply-to-the-penis-in-suspected-prostate-cancer-patients
#2
Cao Tan Thai, Ibrahim Michel Karam, Phi Linh Nguyen-Thi, Frédéric Lefèvre, Jacques Hubert, Jacques Felblinger, Pascal Eschwège
PURPOSE: To describe the internal pudendal artery (IPA) and accessory pudendal artery (APA) detected by magnetic resonance (MR) angiography to help surgeons to find and preserve them during radical prostatectomy (RP). MATERIALS AND METHODS: Constrast-enhanced MR 3.0 T angiography of the pelvis were performed in 111 male patients suspected diagnosis of prostate cancer (PCa), and describe the penile arterial blood supply. RESULTS: There are three patterns of the arterial blood supply to the penis (IPA and/or APA) accounting for 51...
May 2015: European Journal of Radiology
https://www.readbyqxmd.com/read/25469941/value-of-cine-phase-contrast-magnetic-resonance-imaging-to-predict-obstructive-hydrocephalus
#3
M R Weinzierl, T Krings, C Ocklenburg, M C Korinth
BACKGROUND: This is a prospective study to evaluate the role of CINE MRI to predict obstructive hydrocephalus in the preoperative work-up. PATIENTS/MATERIAL AND METHODS: A total of 16 patients with aqueductal obstruction demonstrated by CINE MRI who were undergoing ETV were included. MRI was performed preoperatively, at 3 months, at 12 months and at 24 months after surgery. Prior to the fenestration of the third ventricular floor aqueductal patency was evaluated using intraoperative ventriculography...
January 2012: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/22272217/targeting-strategies-for-multifunctional-nanoparticles-in-cancer-imaging-and-therapy
#4
Mi Kyung Yu, Jinho Park, Sangyong Jon
Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have shown potential as multifunctional nanoparticles for clinical translation because they have been used asmagnetic resonance imaging (MRI) constrast agents in clinic and their features could be easily tailored by including targeting moieties, fluorescence dyes, or therapeutic agents...
2012: Theranostics
https://www.readbyqxmd.com/read/21924038/-analysis-of-prognostic-factors-in-nsclc-patients-with-brain-metastases-%C3%A2-diagnosed-by-constrast-enhanced-mri-after-whole-brain-radiotherapy
#5
Hui Liu, Qiongya Wu, Xiaomei Gong, Xiaodong He, Hongyu Wu, Zhaoying Sheng, Dao'an Zhou
BACKGROUND AND OBJECTIVE: Brain metastases are a common complication of lung cancer, occurring in 20%-40% of patients. The aim of this study is to explore prognostic factors in non-small cell lung cancer (NSCLC) in patients with brain metastases diagnosed by constrast-enhanced MRI after whole brain radiotherapy. METHODS: TA retrospective review of clinical data from 241 NSCLC patients with brain metastases received whole brain radiotherapy from April 2007 to October 2008 was performed...
September 2011: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/21520891/water-exchange-of-a-prohance-mri-contrast-agent-isomer-dependent-free-energy-landscapes-and-mechanisms
#6
Rodolphe Pollet, Nisanth N Nair, Dominik Marx
The water-exchange reaction in two diastereoisomers of the clinical magnetic resonance imaging contrast agent [Gd(HP-DO3A)(H(2)O)] (also known as ProHance) has been studied using ab initio simulations. On the basis of the molecular-level details of the mechanism derived from these simulations in aqueous solution, we unravel the underlying difference in the free energies and mechanisms of water exchange in the two diastereoisomers. These findings reveal the crucial role played by hydrogen-bonding dynamics and thus suggest their appropriate control in tailoring improved gadolinium-based constrast agents...
June 6, 2011: Inorganic Chemistry
https://www.readbyqxmd.com/read/18939814/solution-structure-of-the-supramolecular-adduct-between-a-liver-cytosolic-bile-acid-binding-protein-and-a-bile-acid-based-gadolinium-iii-chelate-a-potential-hepatospecific-magnetic-resonance-imaging-contrast-agent
#7
Simona Tomaselli, Serena Zanzoni, Laura Ragona, Eliana Gianolio, Silvio Aime, Michael Assfalg, Henriette Molinari
Bile acid-conjugated gadolinium chelates were shown to display promising features for the development of hepatospecific constrast agents for magnetic resonance imaging (MRI). The study of the pharmacokinetics of these compounds should address their possible interaction with the bile acid protein transporters. We have previously shown that a 5beta-cholanoic acid-based contrast agent is efficiently internalized in hepatocytes and is able to bind to a liver bile acid binding protein (BABP) in vitro. Here we report the solution structure of the adduct between a BABP and a gadolinium chelate/bile acid conjugate...
November 13, 2008: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/17249196/characteristic-magnetic-resonance-enhancement-pattern-in-cerebral-schistosomiasis
#8
Han-Qiu Liu, Xiao-Yuan Feng, Zhen-Wei Yao, Hua-Ping Sun
OBJECTIVE: To describe the characteristic magnetic resonance imaging (MRI) appearance of cerebral schistosomiasis. METHODS: Twenty-five patients whose diagnosis of central nervous system (CNS) schistosomiasis had been pathologically (n = 8) and clinically (n = 17) confirmed were randomly selected. MRI was performed on a Signal 1. 5T MRI scanner before and after the intravenous administration of gadopentetate dimeglumine constrast medium. We reviewed the MRI studies obtained at the time of initial presentation, as well as follow-up studies obtained during and after medical treatment...
December 2006: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/7674846/partially-saturated-fluid-attenuated-inversion-recovery-flair-sequences-in-multiple-sclerosis-comparison-with-fully-relaxed-flair-and-conventional-spin-echo
#9
COMPARATIVE STUDY
C Baratti, F Barkhof, F Hoogenraad, J Valk
Fluid attenuated inversion recovery (FLAIR) sequences produce selective cerebrospinal fluid (CSF) suppression by employing a very long inversion time (TI). We used the FLAIR sequence to study patients with multiple sclerosis (MS) at 0.6 T. So far, a very long TR (and long acquisition time) has been used in a fully relaxed (FR-FLAIR) system. To speed up the FLAIR sequences, we used a shorter TR, and demonstrated that complete CSF suppression can be maintained with partial saturation (PS-FLAIR) by reducing TI at the same time...
1995: Magnetic Resonance Imaging
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