keyword
https://read.qxmd.com/read/38644459/detection-algorithms-for-gastrointestinal-perforation-cases-in-the-medical-information-database-network-mid-net-%C3%A2-in-japan
#21
JOURNAL ARTICLE
Masatoshi Tanigawa, Mei Kohama, Kaori Hirata, Rieko Izukura, Tadashi Kandabashi, Yoko Kataoka, Naoki Nakashima, Michio Kimura, Yoshiaki Uyama, Hideto Yokoi
BACKGROUND: The Medical Information Database Network (MID-NET® ) in Japan is a vast repository providing an essential pharmacovigilance tool. Gastrointestinal perforation (GIP) is a critical adverse drug event, yet no well-established GIP identification algorithm exists in MID-NET® . METHODS: This study evaluated 12 identification algorithms by combining ICD-10 codes with GIP therapeutic procedures. Two sites contributed 200 inpatients with GIP-suggestive ICD-10 codes (100 inpatients each), while a third site contributed 165 inpatients with GIP-suggestive ICD-10 codes and antimicrobial prescriptions...
April 21, 2024: Therapeutic Innovation & Regulatory Science
https://read.qxmd.com/read/38644423/gender-differences-in-spinal-mobility-during-postural-changes-a-detailed-analysis-using-upright-ct
#22
JOURNAL ARTICLE
Ryo Mizukoshi, Mitsuru Yagi, Yoshitake Yamada, Yoichi Yokoyama, Minoru Yamada, Kota Watanabe, Masaya Nakamura, Takeo Nagura, Masahiro Jinzaki
Lumbar spinal alignment is crucial for spine biomechanics and is linked to various spinal pathologies. However, limited research has explored gender-specific differences using CT scans. The objective was to evaluate and compare lumbar spinal alignment between standing and sitting CT in healthy individuals, focusing on gender differences. 24 young and 25 elderly males (M) and females (F) underwent standing and sitting CT scans to assess lumbar spinal alignment. Parameters measured and compared between genders included lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT), pelvic incidence (PI), lordotic angle (LA), foraminal height (FH), and bony boundary area (BBA)...
April 21, 2024: Scientific Reports
https://read.qxmd.com/read/38644314/-a-case-of-intestinal-obstruction-due-to-an-internal-hernia-in-the-mesenteric-defect-after-laparoscopic-resection-of-transverse-colon
#23
JOURNAL ARTICLE
Takuya Fujimoto
72-year-old man who was diagnosed with transverse colon cancer cT3N1aM0, Stage Ⅲb, and underwent laparoscopic- assisted resection of the transverse colon. Postoperatively, the patient was discharged from the hospital after 24 days due to complications such as paralytic ileus and intra-abdominal abscess caused by prolonged intestinal congestion. On postoperative day 91, the patient developed abdominal pain and vomiting at home, and was rushed to our hospital on the same day. Abdominal CT showed that an internal hernia had formed in the mesenteric defect after resection of the transverse colon, which was suspected to have caused obstruction of the small intestine...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38643835/functional-imaging-in-neuroendocrine-tumors-assessment-of-molecular-heterogeneity-using-68ga-ga-dota-toc-and-18%C3%A2-f-fdg-pet-ct
#24
JOURNAL ARTICLE
Z Nogareda Seoane, M C Mallón Araújo, A Calatayud Cubes, C Barberán Corral, Y Domínguez Novoa, A Cousillas Castiñeira, N Martínez Lago, J M de Matías Leralta, V Pubul Nuñez
OBJECTIVE: The aim of the study was evaluate the diagnostic performance of [68Ga]Ga-DOTA-TOC and [18 F]FDG PET/CT in patients with histologically proven neuroendocrine tumors (NETs), as well as the correlation of the visualized findings with the tumor grade. MATERIAL AND METHODS: We included 50 patients with NETs who underwent both [68Ga]Ga-DOTA-TOC and [18 F]FDG PET/TC. The pooled sensitivity of both scans was compared, as well as [68Ga]Ga-DOTA-TOC and [18 F]FDG for each tumor grade (grade 1/G1, grade 2/G2 and grade 3/G3)...
April 19, 2024: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/38642959/target-sign-in-covid-19-radiological-interpretation-and-diagnostic-contribution-of-digital-thoracic-tomosynthesis
#25
JOURNAL ARTICLE
J M Plasencia Martínez, I García Tuells, C Bravo Pérez, A Blanco Barrio
INTRODUCTION: Our objectives are: To describe the radiological semiology, clinical-analytical features and prognosis related to the target sign (TS) in COVID-19. To determine whether digital thoracic tomosynthesis (DTT) improves the diagnostic ability of radiography. MATERIAL AND METHODS: Retrospective, descriptive, single-centre, case series study, accepted by our ethical committee. Radiological, clinical, analytical and follow-up characteristics of patients with COVID-19 and TS on radiography and DTT between November 2020 and January 2021 were analysed...
April 2024: Radiología
https://read.qxmd.com/read/38642956/prevalence-and-prognostic-meaning-of-interstitial-lung-abnormalities-in-remote-ct-scans-of-patients-with-interstitial-lung-disease-treated-with-antifibrotic-therapy
#26
JOURNAL ARTICLE
M M García Mullor, J J Arenas-Jiménez, A Ureña Vacas, I Gayá García-Manso, J L Pérez Pérez, N Serra Serra, R García Sevila
OBJECTIVES: To describe the prevalence and characteristics of interstitial lung abnormalities (ILA) in CT scans performed prior to the initiation of antifibrotics in a series of patients with interstitial lung disease (ILD), and to identify characteristics apparent on early CT scans that could help to predict outcomes. METHODS: We conducted a retrospective observational study. The original cohort consisted of 101 patients diagnosed with ILD and treated with antifibrotics in a tertiary hospital...
April 2024: Radiología
https://read.qxmd.com/read/38642488/novel-findings-in-a-swedish-primary-familial-brain-calcification-cohort
#27
JOURNAL ARTICLE
Stefan Sennfält, Peter Gustavsson, Helena Malmgren, Eric Gilland, Håkan Almqvist, Mikael Oscarson, Martin Engvall, Ingemar Björkhem, Daniel Nilsson, Kristina Lagerstedt-Robinson, Per Svenningsson, Martin Paucar
INTRODUCTION: Brain calcifications are frequent findings on imaging. In a small proportion of cases, these calcifications are associated with pathogenic gene variants, hence termed primary familial brain calcification (PFBC). The clinical penetrance is incomplete and phenotypic variability is substantial. This paper aims to characterize a Swedish PFBC cohort including 25 patients: 20 from seven families and five sporadic cases. METHODS: Longitudinal clinical assessment and CT imaging were conducted, abnormalities were assessed using the total calcification score (TCS)...
April 18, 2024: Journal of the Neurological Sciences
https://read.qxmd.com/read/38642294/intracranial-extra-axial-chondromas-clues-to-computed-tomography-and-magnetic-resonance-imaging-diagnosis
#28
JOURNAL ARTICLE
Mustafa Kemal Demir, Özlem Yapıcıer, Önder Ertem, Ozge Ecertastan, Deniz Kılıc, Aslan Güzel, Türker Kılıc
AIM: We aimed to describe the computed tomography (CT) and magnetic resonance (MR) imaging findings of intracranial extra-axial chondroma. MATERIAL AND METHODS: We retrospectively evaluated the imaging findings of CT and MR examinations of six patients (three men and three women, aged 21-66 years) with histopathological diagnoses of intracranial extra-axial chondroma. RESULTS: Four tumors were located in the frontal region and two in the cavernous sinus...
April 20, 2024: Acta Neurologica Belgica
https://read.qxmd.com/read/38642134/myd88-in-osteoclast-and-osteoblast-lineages-differentially-controls-bone-remodeling-in-homeostasis-and-malaria
#29
JOURNAL ARTICLE
Jalal Alshaweesh, Rashmi Dash, Michelle S J Lee, Pinar Kahyaoglu, Ece Erci, Mengling Xu, Julia Matsuo-Dapaah, Camila Del Rosario Zorrilla, Kubra Aykac, Suheyla Ekemen, Kouji Kobiyama, Ken J Ishii, Cevayir Coban
Chronic bone loss is an under-recognized complication of malaria, the underlying mechanism of which remains incompletely understood. We have previously shown that persistent accumulation of Plasmodium products in the bone marrow leads to chronic inflammation in osteoblast (OB) and osteoclast (OC) precursors causing bone loss through MyD88, an adaptor molecule for diverse inflammatory signals. However, the specific contribution of MyD88 signaling in OB or OC precursors in malaria-induced bone loss remains elusive...
April 20, 2024: International Immunology
https://read.qxmd.com/read/38641909/covid-19-associated-pulmonary-embolism-clinical-biochemical-and-ct-imaging-findings
#30
JOURNAL ARTICLE
Eduard Dumea, Mihai Lazar, Cristina Emilia Chitu-Tisu, Ecaterina Constanta Barbu, Daniela Adriana Ion
INTRODUCTION: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection represented a disruptive pathology that emerged in late 2019 with profound implications ranging from individual health to health systems and world economy. Our study aimed to evaluate clinical, biochemical and computerized tomography (CT) parameters values in determining the severity of pulmonary embolism (PE) associated with COVID-19. METHODS: We performed an observational cohort study evaluating demographic, clinical, biochemical, coagulation markers, as well as CT imaging parameters...
April 19, 2024: Romanian Journal of Internal Medicine
https://read.qxmd.com/read/38641426/changes-in-chlamydia-trachomatis-risk-before-and-after-union-formation-and-separation-among-women-of-reproductive-age
#31
JOURNAL ARTICLE
Niina S Metsä-Simola, Elina K Einiö, Pekka T Martikainen
BACKGROUND: Not having an established relationship is associated with an elevated risk of Chlamydia trachomatis (CT) infection, but this might reflect selection into and out of unions. Although union formation and union separation are common events in reproductive age, little is known about changes in CT risk before and after these transitions. METHODS: We linked Finnish Population Register data to the National Register of Infectious Diseases and used fixed-effects linear probability models that account for all time-invariant confounders to examine changes in women's 6-month CT risk 3 years before and 3 years after entry into first cohabitation (n = 293 554), non-marital separation (n = 201 647) or marital separation (n = 92 232) during 2005-14...
April 19, 2024: European Journal of Public Health
https://read.qxmd.com/read/38641181/retinal-and-choroidal-changes-after-anti-vegf-therapy-in-neovascular-amd-patients-a-systematic-review-and-meta-analysis-of-sd-oct-studies
#32
REVIEW
Mohammad Amin Salehi, Negin Frounchi, Seyed Sina Zakavi, Soheil Mohammadi, Hamid Harandi, Shayan Shojaei, Mahdi Gouravani, J Fernando Arevalo
BACKGROUND: In recent years, the progress made in the field of optical coherence tomography (OCT) has helped to understand the changes in eye layers in patients with exudative age-related macular degeneration (AMD). Early diagnosis of AMD as a leading cause of irreversible vision impairment is helpful. Therefore, we aim to perform a meta-analysis on OCT measurement alterations before and after anti-VEGF therapy in patients with AMD and controls. METHOD: We systematically searched Scopus, PubMed, Cochrane, and Web of Science to find articles that measured choroidal and retinal layer changes after anti-VEGF therapy in AMD Patients...
April 17, 2024: Survey of Ophthalmology
https://read.qxmd.com/read/38640873/musket-ball-injuries-to-the-head-experimental-ct-study
#33
Juho-Antti Junno, Jaakko Niinimäki, Markku Niskanen, Alina Junno, Heli Maijanen, Petteri Oura
A smoothbore musket firing a round ball was the primary weapon of the infantry from the 16th to mid 19th century. Musket ball injuries are thus relatively common when archaeological remains of battlefield victims from that period are studied. Several experimental studies have focused on terminal ballistics of a musket ball. In addition, there is a good supply of historical records directly from the battlefield and military hospitals. Studies and historical records have both concluded that head injuries are among the most lethal types of musket ball damage...
April 16, 2024: Legal Medicine
https://read.qxmd.com/read/38640725/association-of-early-seizures-after-ischemic-stroke-with-diffusion-weighted-imaging-alberta-stroke-program-early-ct-score-dwi-aspects-and-neutrophil-to-lymphocyte-ratio
#34
JOURNAL ARTICLE
Maryam Ebrahimian, Mohamad Hosein Mohamadi, Mahshid Mahyad, Fariborz Rezaeitalab
BACKGROUND: Post-stroke seizure (PSS) is a common considerable complication of acute ischemic stroke (AIS). Early risk assessment can clinical practitioners to plan effective prevention and management. We aimed to determine whether assessing Diffusion-Weighted Imaging-Alberta Stroke Program Early CT Score (DWI-ASPECTS), and neutrophil indices allows for identifying patients at risk of PSS. METHODS: This prospective study included AIS patients with cortical involvement admitted to a single academic center between January 2020 to October 2023...
April 18, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38640562/dissolved-organic-matter-isolates-obtained-by-solid-phase-extraction-exhibit-higher-absorption-and-lower-photo-reactivity-effect-of-components
#35
JOURNAL ARTICLE
Roujia Du, Jiaqi Wen, Jun Huang, Qianxin Zhang, Xiaoyu Shi, Bin Wang, Shubo Deng, Gang Yu
Notable differences in photo-physical and chemical properties were found between bulk water and solid phase extraction (SPE) isolates for dissolved organic matter (DOM). The moieties extracted using modified styrene divinylbenzene cartridges, which predominantly consist of conjugated aromatic molecules like humic acids, contribute mainly to light absorption but exhibit lower quantum yields of fluorescence and photo-produced reactive intermediates (PPRIs). Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) revealed lignin as the moieties displaying most significant variance in abundance...
April 11, 2024: Water Research
https://read.qxmd.com/read/38640323/radiofrequency-regulation-of-the-sphenopalatine-ganglion-in-managing-herpes-zoster-ophthalmicus-neuralgia-a-case-series
#36
JOURNAL ARTICLE
Min Cui, Na Zhang, Dong Wang, Lei Han
INTRODUCTION: Trigeminal herpes zoster, which comprises 10% to 20% of cases of herpes zoster, often leads to severe pain in the ophthalmic branches. Current treatments, including drug therapy and minimally invasive interventions, have limitations; accordingly, there is a need to explore alternative approaches. This study aimed to evaluate the efficacy and safety of computerized tomography (CT)-guided pulsed radiofrequency of the sphenopalatine ganglion in patients with intractable trigeminal herpetic pain...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38639385/diagnostic-performance-of-18f-fdg-positron-emission-tomography-computed-tomography-and-blood-test-parameters-for-pulmonary-inflammatory-pseudotumor
#37
JOURNAL ARTICLE
Bo Pan, Yanming Wang, Zehua Zhu, Xingxing Zhu
PURPOSE: Pulmonary inflammatory pseudotumor (PIP) is an inflammatory proliferative tumor-like lesion that frequently exhibits hypermetabolism on 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography imaging (PET/CT) and is readily misdiagnosed as a malignant tumor. The purpose of this study was to identify PIP by combining PET/computed tomography metabolic and blood test characteristics with machine learning. PATIENTS AND METHODS: We recruited 27 patients with PIP and 28 patients with lung cancer (LC)...
April 18, 2024: Journal of Thoracic Imaging
https://read.qxmd.com/read/38639349/long-term-clinical-implications-of-high-risk-cardiac-computed-tomography-findings-in-patients-with-acute-ischemic-stroke
#38
JOURNAL ARTICLE
Leon A Rinkel, Olivia N Cramer, Z Beyda Özata, Chiel F P Beemsterboer, Valeria Guglielmi, Shan Sui Nio, Berto J Bouma, S Matthijs Boekholdt, Nick H J Lobé, Ludo F M Beenen, Henk A Marquering, Charles B L M Majoie, Yvo B W E M Roos, Adrienne van Randen, R Nils Planken, Jonathan M Coutinho
BACKGROUND: Cardiac computed tomography (CT) acquired during the initial acute stroke imaging protocol (acute cardiac CT) is increasingly used to screen for cardioembolism, but information on the long-term clinical implications of its findings is lacking. METHODS AND RESULTS: We performed a prospective, single-center cohort study in which consecutive patients with ischemic stroke underwent ECG-gated acute cardiac CT and were followed up for 2 years. The primary outcome was functional outcome assessed using the modified Rankin Scale...
April 19, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38639283/imaging-findings-of-calcifying-nested-stromal-epithelial-tumour-of-the-liver-a-case-report-and-literature-review
#39
Ermin Cai, Yiheng Zheng, Mingliang Wang, Mengsu Zeng
BACKGROUND: A calcifying nested stromal-epithelial tumour (CNSET) is an erratic primary liver malignant tumour frequently discovered in young girls and females. Neither its pathogenesis nor its nosogenesis is clearly known. While principally indolent, infrequent tumours with aggressive clinical progression have been defined. This paper describes a CNSET case with rare clinical and imaging features. CASE PRESENTATION: A 17-year-old girl initially presented with enlarged lymph nodes near the main portal vein of the liver and a large liver tumour...
April 18, 2024: Current medical imaging
https://read.qxmd.com/read/38638552/inguinal-hernia-leading-to-omental-torsion-role-of-ct-in-differentiating-from-other-clinical-mimics-a-case-report-and-literature-review
#40
Ali Mansoor, Rabia Shaukat
Omental torsion is a very rare cause of acute abdomen. Clinically, it mimics other common pathologies such as acute appendicitis, acute diverticulitis and acute cholecystitis. It is therefore no surprise, that it was rarely diagnosed pre operatively before the advent and easy availability of modern imaging techniques. CT scan, in particular, can diagnose omental torsion with confidence pre operatively. This can make conservative treatment possible in cases of primary omental torsion and guide regarding the appropriate treatment in cases of secondary torsion...
November 2023: Journal of Radiology Case Reports
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