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CRT training

Ana Abreu, Helena Santa Clara
Cardiac resynchronization therapy (CRT) is an established treatment for patients with moderate-to-severe chronic heart failure (CHF) and intraventricular conduction delay, which is identified by a QRS interval of 120msec or more on a 12-lead electrocardiogram (ECG). CRT improved functional capacity, reduced hospitalizations for worsening CHF and increased survival. However, about 30-40% of patients who underwent CRT were non-responders with no clinical or echocardiographic improvement. Imaging parameters for prediction of CRT response have been reviewed...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Marie Christine Iliou, Jean Christophe Blanchard, Aurélia Lamar-Tanguy, Pascal Cristofini, François Ledru
Large subsets of patients admitted in cardiac rehabilitation centers are having a pacemaker, cardiac resynchronization (CRT) or implantable cardiac defibrillator (ICD). Cardiac rehabilitation for patients, mostly with heart failure, with implanted electronic devices as pacemakers or ICD is a unique opportunity not only to optimize the medical treatment, to increase their exercise capacity and improves their clinical condition but also to supervise the correct functioning of the device. CRT reduces clinical symptoms and increases slightly the exercise capacity...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Mehmet Mihmanlı, Esin Kabul Gürbulak, İsmail Ethem Akgün, Mustafa Fevzi Celayir, Pınar Yazıcı, Deniz Tunçel, Tuba Tülin Bek, Ayhan Öz, Sinan Ömeroğlu
AIM: To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy (CRT) and surgery in locally advanced rectal cancer. METHODS: We evaluated 87 patients with locally advanced mid- or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at Şişli Hamidiye Etfal Training and Research Hospital, Istanbul between January 2009 and January 2014. Patients were divided into two groups according to the interval before surgery: < 8 wk (group I) and ≥ 8 wk (group II)...
September 15, 2016: World Journal of Gastrointestinal Oncology
Barbara Couden Hernandez, Lana Kim, Adrian Lavery, T Kent Denmark
Replies to comments by DeCaporale-Ryan, Dadiz, and Peyre (see record ) on the original article by Kim, Hernandez, Lavery, and Denmark (see record ). The current authors thank DeCaporale-Ryan, Dadiz, and Peyre for presenting a rich theoretical counterpoint to their article and respond to issues they raised regarding their collaborative reflecting team (CRT) model. (PsycINFO Database Record
September 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Tim Vanbellingen, Manuela Wapp, Katharina Stegmayer, Manuel Bertschi, Eugenio Abela, Stefanie Kübel, Thomas Nyffeler, René Müri, Sebastian Walther, Tobias Nef, Mark Hallett, Stephan Bohlhalter
Dorsal pre-motor cortex (PMd) is thought to play a role in fine motor control. The aim of the present study was to investigate whether inhibitory or excitatory stimulation of PMd would have an impact on manual dexterity in Parkinson's disease (PD). Fifteen patients with PD participated in this study. High resolution structural MRI was used for neuro-navigated TBS. Participants were targeted with one train of TBS in three experimental sessions: sham stimulation over vertex, continuous TBS (cTBS) over PMd and intermittent TBS (iTBS) over PMd, respectively...
September 12, 2016: Journal of Neural Transmission
Thais S Nobre, Ligia M Antunes-Correa, Raphaela V Groehs, Maria-Janieire N N Alves, Adriana O Sarmento, Aline Villa Nova Bacurau, Ursula Urias, Guilherme Barreto Alves, Maria Urbana P B Rondon, Patricia C Brum, Martino Martinelli, Holly R Middlekauff, Carlos E Negrao
Heart failure(HF) is characterized by decreased exercise capacity, attributable to neurocirculatory and skeletal muscle factors. Cardiac resynchronization therapy(CRT) and exercise training have each been shown to decrease muscle sympathetic nerve activity(MSNA) and increase exercise capacity in patients with HF. We hypothesized that exercise training in the setting of CRT would further reduce MSNA and vasoconstriction and would increase Ca(2+) handling gene expression in skeletal muscle in chronic systolic HF patients...
September 2, 2016: American Journal of Physiology. Heart and Circulatory Physiology
Jing Yu, Ning Li, Xin Wang, Hua Ren, Weihu Wang, Shulian Wang, Yongwen Song, Yueping Liu, Yexiong Li, Xuantong Zhou, Aiping Luo, Zhihua Liu, Jing Jin
Preoperative chemoradiotherapy (pre-CRT) has been represented as the standard treatment for locally advanced rectal cancer (LARC), but large variations of tumor radiation response to CRT have been reported in the clinic. To explore the function of microRNAs as potential therapeutic predictors of pre-CRT pathological response in LARC, we analyzed global miRNA expression in CRT-sensitive and CRT-resistant groups before treatment. MiR-345 was significantly elevated in the CRT-resistant group. Therefore, miR-345 was selected as a candidate for further analysis...
August 27, 2016: Oncotarget
Xiaojuan Xia, Anne-Christine Ruwald, Martin H Ruwald, Nene Ugoeke, Barbara Szepietowska, Valentina Kutyifa, Mehmet K Aktas, Poul Erik B Thomsen, Wojciech Zareba, Arthur J Moss, Jean-Philippe Couderc
AIMS: Strict left bundle branch block (LBBB) criteria were recently proposed to identify LBBB patients to benefit most from cardiac resynchronization therapy (CRT). The aim of our study was to automate identification of strict LBBB in order to facilitate its broader application. METHODS: We developed a series of algorithms to automatically detect and measure parameters required for strict LBBB criteria and proposed a definition of QRS notch detection. The algorithms were developed using training (n = 20) and validation (n = 592) sets consisting of signal-averaged 12-lead ECGs (1,000 Hz sampling) recorded from 612 LBBB patients from Multicenter Automatic Defibrillator Implantation Trial-CRT...
August 30, 2016: Annals of Noninvasive Electrocardiology
Audrey Benoit, Philippe-Olivier Harvey, Louis Bherer, Martin Lepage
Cognitive remediation therapy (CRT) has emerged as a viable treatment option for people diagnosed with schizophrenia presenting disabling cognitive deficits. However, it is important to determine which variables can influence response to CRT in order to provide cost-effective treatment. This study's aim was to explore cognitive insight as a potential predictor of cognitive improvement after CRT. Twenty patients with schizophrenia completed a 24-session CRT program involving 18 hours of computer exercises and 6 hours of group discussion to encourage generalization of cognitive training to everyday activities...
2016: Schizophrenia Research and Treatment
Razvan O Mada, Peter Lysyansky, Jürgen Duchenne, Ruxandra Beyer, Cristina Mada, Lucian Muresan, Horia Rosianu, Adela Serban, Stefan Winter, Wolfgang Fehske, Ivan Stankovic, Jens-Uwe Voigt
BACKGROUND: New echocardiographic parameters (apical rocking [AR], septal flash [SF]) are intended to detect patterns specific to responders to cardiac resynchronization therapy (CRT). The patterns are visually recognized and qualitatively described, requiring experience and training. Speckle-tracking echocardiography can reflect SF and AR by using newly developed, dedicated parameters, such as start systolic index (SSI) and peak longitudinal displacement (PLD). The aim of this study was to investigate whether SSI and PLD can identify potential CRT responders...
October 2016: Journal of the American Society of Echocardiography
Xiao-Jie Wang, Pan Chi, Hui-Ming Lin, Xing-Rong Lu, Ying Huang, Zong-Bin Xu, Sheng-Hui Huang, Yan-Wu Sun, Dao-Xiong Ye, Qian Yu
Local excision is an alternative to radical surgery that is indicated in patients with locally advanced rectal cancer (LARC) who have a good response to chemoradiotherapy (CRT). Regional lymph node status is a major uncertainty during local excision of LARC following CRT. We retrospectively reviewed clinicopathologic variables for 244 patients with LARC who were treated at our institute between December 2000 and December 2013 in order to identify independent predictors of regional lymph node metastasis. Multivariate analysis of the training sample demonstrated that histopathologic type, tumor size, and the presence of lymphovascular invasion were significant predictors of regional nodal metastasis...
July 30, 2016: Oncotarget
Fabiano C Ferreira, Danilo R Bertucci, Marina R Barbosa, Joao E Nunes, Joao P Botero, Maria F Rodrigues, Gilberto E Shiguemoto, Valdir Santoro, Ana C Verzola, Rodrigo O Nonaka, Roberto M Verzola, Vilmar Baldissera, Sergio Perez
BACKGROUND: Normal weight obesity (NWO) syndrome has been characterised in subjects with normal BMI and high body fat mass percentage (BF% >30 for women) being a risk factor for cardiometabolic dysregulation and cardiovascular mortality. This study evaluated whether circuit resistance training (CRT) improves body composition, heart size and function, cardiometabolic parameters, and cardiorespiratory, cardiovascular and skeletal muscle fitness in women with NWO. METHODS: Data are means [95% Confidence Interval]...
July 6, 2016: Journal of Sports Medicine and Physical Fitness
Mary Stapleton
BACKGROUND: Animal Assisted Therapy (AAT) has been widely used as a complementary therapy in mental health treatment especially to remediate social skill deficits. The goal of AAT is to improve social, emotional, and cognitive functioning. OBJECTIVE: The purpose of this article is to draw upon the literature on AAT and explore specific applications to cognitive rehabilitation therapy (CRT) and social skills training. METHODS: This study provides a systematic review of most of the available literature on ATT and assesses that potential uses of ATT for brain injury rehabilitation...
June 18, 2016: NeuroRehabilitation
J Hogeveen, J Grafman, M Aboseria, A David, M Bikson, K K Hauner
BACKGROUND: Response inhibition is a critical executive function, enabling the adaptive control of behavior in a changing environment. The inferior frontal cortex (IFC) is considered to be critical for response inhibition, leading researchers to develop transcranial direct current stimulation (tDCS) montages attempting to target the IFC and improve inhibitory performance. However, conventional tDCS montages produce diffuse current through the brain, making it difficult to establish causality between stimulation of any one given brain region and resulting behavioral changes...
September 2016: Brain Stimulation
Nidhal Zarrouk, Omar Hammouda, Imed Latiri, Hela Adala, Ezzedine Bouhlel, Haithem Rebai, Mohamed Dogui
BACKGROUND: The present study aimed to investigate the concomitant effects of Ramadan intermittent fast (RIF) and muscle fatigue on neuromuscular performances and reaction times in young trained athletes. METHODS: Eight karate players (17.2 ± 0.5 years) were tested on three sessions: during a control period (S1: one week before Ramadan), and during the first (S2) and the fourth week of RIF (S3). Dietary intake and anthropometric measurements were assessed before each session...
2016: Journal of the International Society of Sports Nutrition
Lana Kim, Barbara Couden Hernandez, Adrian Lavery, T Kent Denmark
Medical simulation has long been used as a way to immerse trainees in realistic practice scenarios to help them consolidate their formal medical knowledge and develop teamwork, communication, and technical skills. Debriefing is regarded as a critical aspect of simulation training. With a skilled debriefing facilitator, trainees are able to go beyond a rote review of the skills and steps taken to explore their internal process and self-reflect on how their experience during the simulation shaped their decision making and behavior...
June 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Antonio Curcio, Salvatore DE Rosa, Jolanda Sabatino, Simona DE Luca, Angela Bochicchio, Alberto Polimeni, Giuseppe Santarpia, Pietrantonio Ricci, Ciro Indolfi
BACKGROUND: Appropriate selection of implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT) device can be challenging in patients with left ventricular (LV) dysfunction. In this setting, limited information exists about the role of medical applications in helping physicians to choose the most useful device. METHODS: We developed a medical application that provides guidelines-based algorithms for helping doctors in decision process using the Apache Cordova application programming interface...
July 2016: Pacing and Clinical Electrophysiology: PACE
Michael Pittaro, William Deforge, Mark W Kroll
BACKGROUND: Determination of an adequate defibrillation safety margin or defibrillation threshold can be a challenge in patients with implantable defibrillators (ICDs). The upper limit of vulnerability (ULV) has been shown to be highly correlated with measured defibrillation thresholds. The peak of the latest peaking monophasic T wave measured from the pacing spike of the induction train of S1 via the surface electrocardiogram (ECG) is generally accepted to approximate the vulnerable period of the cardiac cycle...
July 2016: Pacing and Clinical Electrophysiology: PACE
Adem Yildirim, Gülseren Dost Sürücü, Ayşe Karamercan, Dilay Eken Gedik, Nermin Atci, Deniz Dülgeroǧlu, Neşe Özgirgin
BACKGROUND AND OBJECTIVES: A number of exercises to strengthen the upper extremities are recommended to increase functional independence and quality of life (QoL) in patients with paraplegia. Circuit resistance training (CRT) is a type of progressive resistive exercise performed repeatedly at fixed mechanical exercise stations. The aim of this study was to investigate the potential benefits of CRT for upper extremity muscle strength, functional independence, and QoL in patients with paraplegia...
March 18, 2016: Journal of Back and Musculoskeletal Rehabilitation
Lisa Loughney, Malcolm A West, Graham J Kemp, Harry B Rossiter, Shaunna M Burke, Trevor Cox, Christopher P Barben, Michael G Mythen, Peter Calverley, Daniel H Palmer, Michael P W Grocott, Sandy Jack
BACKGROUND: The standard treatment pathway for locally advanced rectal cancer is neoadjuvant chemoradiotherapy (CRT) followed by surgery. Neoadjuvant CRT has been shown to decrease physical fitness, and this decrease is associated with increased post-operative morbidity. Exercise training can stimulate skeletal muscle adaptations such as increased mitochondrial content and improved oxygen uptake capacity, both of which are contributors to physical fitness. The aims of the EMPOWER trial are to assess the effects of neoadjuvant CRT and an in-hospital exercise training programme on physical fitness, health-related quality of life (HRQoL), and physical activity levels, as well as post-operative morbidity and cancer staging...
2016: Trials
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