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https://www.readbyqxmd.com/read/28345508/use-of-a-novel-portable-led-based-capillary-refill-time-simulator-within-a-disaster-triage-context
#1
Todd P Chang, Genevieve Santillanes, Ilene Claudius, Phung K Pham, James Koved, John Cheyne, Marianne Gausche-Hill, Amy H Kaji, Saranya Srinivasan, J Joelle Donofrio, Cynthia Bir
Introduction A simple, portable capillary refill time (CRT) simulator is not commercially available. This device would be useful in mass-casualty simulations with multiple volunteers or mannequins depicting a variety of clinical findings and CRTs. The objective of this study was to develop and evaluate a prototype CRT simulator in a disaster simulation context. METHODS: A CRT prototype simulator was developed by embedding a pressure-sensitive piezo crystal, and a single red light-emitting diode (LED) light was embedded, within a flesh-toned resin...
March 27, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28297307/development-and-evaluation-of-a-clinical-model-for-lung-cancer-patients-using-stereotactic-body-radiotherapy-sbrt-within-a-knowledge-based-algorithm-for-treatment-planning
#2
Karen Chin Snyder, Jinkoo Kim, Anne Reding, Corey Fraser, James Gordon, Munther Ajlouni, Benjamin Movsas, Indrin J Chetty
The purpose of this study was to describe the development of a clinical model for lung cancer patients treated with stereotactic body radiotherapy (SBRT) within a knowledge-based algorithm for treatment planning, and to evaluate the model performance and applicability to different planning techniques, tumor locations, and beam arrangements. 105 SBRT plans for lung cancer patients previously treated at our institution were included in the development of the knowledge-based model (KBM). The KBM was trained with a combination of IMRT, VMAT, and 3D CRT techniques...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28290875/-clinical-and-economic-aspects-of-meldonium-as-part-of-physical-rehabilitation-programs-in-patients-with-coronary-heart-disease-after-percutaneous-coronary-interventions
#3
N P Lyamina, I B Razborov, E S Karpov
PURPOSE: to analyze clinical and economical effectiveness of meldonium as component of integrated program of cardio-rehabilitation in patients with ischemic heart disease (IHD) in the early period after percutaneous coronary intervention (PCI) with incomplete revascularization. MATERIAL AND METHODS: A program of controlled physical training (CPT) was carried out in patients with stable IHD and positive post PCI exercise test (n=48, age less or equal 65 years) starting 8-10 days after PCI...
August 2016: Kardiologiia
https://www.readbyqxmd.com/read/28282741/effects-of-acute-exercise-dehydration-and-rehydration-on-cognitive-function-in-well-trained-athletes
#4
Christopher Irwin, Nadia Campagnolo, Elizaveta Iudakhina, Gregory R Cox, Ben Desbrow
This study investigated the effects of aerobic exercise, fluid loss and rehydration on cognitive performance in well-trained athletes. Ten endurance-trained males (25 ± 5 years; 175 ± 5 cm; 70.35 ± 5.46 kg; VO2max, 62.95 ± 7.20 ml · kg.min(-1)) lost ~2.5 ± 0.6% body mass via continuous cycling exercise at ~65% peak sustainable power output (60 min duration) before consuming different beverages (Water = W1 and W2, Sustagen Sport = SS, Powerade = PD) and food ad libitum on four separate occasions...
March 2, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28228938/physical-activity-levels-in-locally-advanced-rectal-cancer-patients-following-neoadjuvant-chemoradiotherapy-and-an-exercise-training-programme-before-surgery-a-pilot-study
#5
Lisa Loughney, Malcolm A West, Borislav D Dimitrov, Graham J Kemp, Michael Pw Grocott, Sandy Jack
BACKGROUND: The aim of this pilot study was to measure changes in physical activity level (PAL) variables, as well as sleep duration and efficiency in people with locally advanced rectal cancer (1) before and after neoadjuvant chemoradiotherapy (CRT) and (2) after participating in a pre-operative 6-week in-hospital exercise training programme, following neoadjuvant CRT prior to major surgery, compared to a usual care control group. METHODS: We prospectively studied 39 consecutive participants (27 males)...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/28225475/stretching-exercises-improve-vascular-endothelial-dysfunction-through-attenuation-of-oxidative-stress-in-chronic-heart-failure-patients-with-an-implantable-cardioverter-defibrillator
#6
Michitaka Kato, Takashi Masuda, Michio Ogano, Kazuki Hotta, Hisato Takagi, Shinya Tanaka, Yumi Kamada, Ayako Akiyama, Daisuke Kamekawa, Ryosuke Shimizu, Minoru Tabata, Jun Tanabe, Takuya Umemoto
PURPOSE: Endurance training improves oxidative stress and vascular endothelial dysfunction in patients with chronic heart failure (CHF). However, patients with CHF and an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) often avoid endurance training for fear of ICD shock. Recent studies have reported that stretching exercises enhance antioxidant activity and improve vascular responses. Therefore, we aimed to assess the effects of 4 weeks of stretching exercises on oxidative stress and vascular endothelial function in patients with CHF with an ICD or CRT-D...
March 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28194306/a-randomized-exploratory-phase-2-study-in-patients-with-chemotherapy-related-peripheral-neuropathy-evaluating-whole-body-vibration-training-as-adjunct-to-an-integrated-program-including-massage-passive-mobilization-and-physical-exercises
#7
Stefan S Schönsteiner, Heidi Bauder Mißbach, Axel Benner, Silja Mack, Thomas Hamel, Michael Orth, Bernhard Landwehrmeyer, Sigurd D Süßmuth, Carolin Geitner, Regine Mayer-Steinacker, Anneliese Riester, Andrea Prokein, Elfriede Erhardt, Jelena Kunecki, Anna M Eisenschink, Rainer Rawer, Hartmut Döhner, Elisabeth Kirchner, Richard F Schlenk
BACKGROUND: Chemotherapy-induced polyneuropathy (CIPN) is a common toxicity after chemotherapy, immunomodulatory drugs or proteasome inhibitors, which is difficult to treat and may also have impact on quality of life. The objective of the study was to evaluate whole-body vibration (WBV) on the background of an integrated program (IP) including massage, passive mobilization and physical exercises on CIPN. PATIENTS AND METHODS: In an exploratory phase-2 study patients with CIPN (NCI CTC grade 2/3) were randomized for WBV plus IP (experimental) to IP alone (standard)...
2017: Experimental Hematology & Oncology
https://www.readbyqxmd.com/read/28127637/-motor-skills-and-safety-of-patients-with-bi-or-trimalleolar-ankle-injury-comparison-with-healthy-active-age-matched-control-subjects
#8
Dana Loudovici-Krug, Monique Benkenstein, Steffen Derlien, Norman Best
OBJECTIVE: Do patients with bi- or trimalleolar ankle injury show differences in motor skills and safety in comparison with healthy, active, age-matched control subjects? STUDY DESIGN: Prospective controlled cross-sectional study. METHODS: Inclusion of 17 patients with bi- or trimalleolar ankle injury (mean 1.5 years postsurgery) and 23 healthy, active subjects of comparable age (fitness studio). Measurement instruments: motor test procedures and questionnaires...
January 26, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28122073/use-of-cardiac-resynchronization-therapy-among-eligible-patients-receiving-an-implantable-cardioverter-defibrillator-insights-from-the-national-cardiovascular-data-registry-implantable-cardioverter-defibrillator-registry
#9
Lucas N Marzec, Pamela N Peterson, Haikun Bao, Jeptha P Curtis, Frederick A Masoudi, Paul D Varosy, Steven M Bradley
Importance: Cardiac resynchronization therapy (CRT) reduces the risk for mortality and heart failure-related events in select patients. Little is known about the use of CRT in combination with an implantable cardioverter defibrillator (ICD) in patients who are eligible for this therapy in clinical practice. Objective: To (1) identify patient, clinician, and hospital characteristics associated with CRT defibrillator (CRT-D) use and (2) determine the extent of hospital-level variation in the use of CRT-D among guideline-eligible patients undergoing ICD placement...
January 25, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28113292/non-invasive-personalisation-of-a-cardiac-electrophysiology-model-from-body-surface-potential-mapping
#10
Sophie Giffard-Roisin, Thomas Jackson, Lauren Fovargue, Jack Lee, Herve Delingette, Reza Razavi, Nicholas Ayache, Maxime Sermesant
Modelling cardiac electrophysiology (EP) can help understand pathologies and predict the response to therapies. Moreover, estimating patient-specific parameters of the EP model is crucial to obtain personalised information. The novelty of this paper is to use non-invasive data (body surface potential mapping, BSPM) in order to personalise the main parameters of a cardiac EP model for predicting different pacing conditions. First, an efficient forward model is proposed, coupling the Mitchell- Schaeffer transmembrane potential model with a current dipole formulation...
November 16, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28046776/su-f-j-207-non-small-cell-lung-cancer-patient-survival-prediction-with-quantitative-tumor-textures-analysis-in-baseline-ct
#11
Y Wu, J Zou, P Murillo, J Nosher, J Amorosa, M Bramwit, N Yue, S Jabbour, D Foran
PURPOSE: Chemo-radiation therapy (CRT) is widely used in treating patients with locally advanced non-small cell lung cancer (NSCLC). Determination of the likelihood of patient response to treatment and optimization of treatment regime is of clinical significance. Up to date, no imaging biomarker has reliably correlated to NSCLC patient survival rate. This pilot study is to extract CT texture information from tumor regions for patient survival prediction. METHODS: Thirteen patients with stage II-III NSCLC were treated using CRT with a median dose of 6210 cGy...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28029405/distributed-learning-developing-a-predictive-model-based-on-data-from-multiple-hospitals-without-data-leaving-the-hospital-a-real-life-proof-of-concept
#12
Arthur Jochems, Timo M Deist, Johan van Soest, Michael Eble, Paul Bulens, Philippe Coucke, Wim Dries, Philippe Lambin, Andre Dekker
PURPOSE: One of the major hurdles in enabling personalized medicine is obtaining sufficient patient data to feed into predictive models. Combining data originating from multiple hospitals is difficult because of ethical, legal, political, and administrative barriers associated with data sharing. In order to avoid these issues, a distributed learning approach can be used. Distributed learning is defined as learning from data without the data leaving the hospital. PATIENTS AND METHODS: Clinical data from 287 lung cancer patients, treated with curative intent with chemoradiation (CRT) or radiotherapy (RT) alone were collected from and stored in 5 different medical institutes (123 patients at MAASTRO (Netherlands, Dutch), 24 at Jessa (Belgium, Dutch), 34 at Liege (Belgium, Dutch and French), 48 at Aachen (Germany, German) and 58 at Eindhoven (Netherlands, Dutch))...
December 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27929499/development-and-evaluation-of-a-clinical-model-for-lung-cancer-patients-using-stereotactic-body-radiotherapy-sbrt-within-a-knowledge-based-algorithm-for-treatment-planning
#13
Karen Chin Snyder, Jinkoo Kim, Anne Reding, Corey Fraser, James Gordon, Munther Ajlouni, Benjamin Movsas, Indrin J Chetty
The purpose of this study was to describe the development of a clinical model for lung cancer patients treated with stereotactic body radiotherapy (SBRT) within a knowledge-based algorithm for treatment planning, and to evaluate the model performance and applicability to different planning techniques, tumor locations, and beam arrangements. 105 SBRT plans for lung cancer patients previously treated at our institution were included in the development of the knowledge-based model (KBM). The KBM was trained with a combination of IMRT, VMAT, and 3D CRT techniques...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27905909/development-of-a-measure-of-model-fidelity-for-mental-health-crisis-resolution-teams
#14
Brynmor Lloyd-Evans, Gary R Bond, Torleif Ruud, Ada Ivanecka, Richard Gray, David Osborn, Fiona Nolan, Claire Henderson, Oliver Mason, Nicky Goater, Kathleen Kelly, Gareth Ambler, Nicola Morant, Steve Onyett, Danielle Lamb, Sarah Fahmy, Ellie Brown, Beth Paterson, Angela Sweeney, David Hindle, Kate Fullarton, Johanna Frerichs, Sonia Johnson
BACKGROUND: Crisis Resolution Teams (CRTs) provide short-term intensive home treatment to people experiencing mental health crisis. Trial evidence suggests CRTs can be effective at reducing hospital admissions and increasing satisfaction with acute care. When scaled up to national level however, CRT implementation and outcomes have been variable. We aimed to develop and test a fidelity scale to assess adherence to a model of best practice for CRTs, based on best available evidence. METHODS: A concept mapping process was used to develop a CRT fidelity scale...
December 1, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27893478/loads-and-movement-speeds-dictate-differences-in-power-output-during-circuit-training
#15
Kirk B Roberson, Sean Chowdhari, Morgan White, Joseph F Signorile
Power training has become a common exercise intervention for improving muscle strength, power, and physical function, while reducing injury risk. Few studies, however, have evaluated acute load changes on power output during traditional resistance-training protocols. Therefore, the aim of this study was to quantify the effects of different loading patterns on power output during a single session of circuit resistance training (CRT). Nine males (age=19.4±0.9 y) and eleven females (age=20.6±1.6 y) completed three CRT protocols during separate testing sessions using seven pneumatic exercises...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27875131/non-invasive-personalisation-of-a-cardiac-electrophysiology-model-from-body-surface-potential-mapping
#16
Sophie Giffard-Roisin, Thomas Jackson, Lauren Fovargue, Jack Lee, Herve Delingette, Reza Razavi, Nicholas Ayache, Maxime Sermesant
Modelling cardiac electrophysiology (EP) can help understand pathologies and predict the response to therapies. Moreover, estimating patient-specific parameters of the EP model is crucial to obtain personalised information. The novelty of this paper is to use non-invasive data (body surface potential mapping, BSPM) in order to personalise the main parameters of a cardiac EP model for predicting different pacing conditions. First, an efficient forward model is proposed, coupling the Mitchell- Schaeffer transmembrane potential model with a current dipole formulation...
November 16, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27748469/imaging-predictive-factors-and-exercise-training-in-crt-patients
#17
Ana Abreu, Helena Santa Clara
Cardiac resynchronization therapy (CRT) is an established treatment for patients with moderate-to-severe chronic heart failure (CHF) and intraventricular conduction delay, which is identified by a QRS interval of 120msec or more on a 12-lead electrocardiogram (ECG). CRT improved functional capacity, reduced hospitalizations for worsening CHF and increased survival. However, about 30-40% of patients who underwent CRT were non-responders with no clinical or echocardiographic improvement. Imaging parameters for prediction of CRT response have been reviewed...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27748467/cardiac-rehabilitation-in-patients-with-pacemakers-and-implantable-cardioverter-defibrillators
#18
Marie Christine Iliou, Jean Christophe Blanchard, Aurélia Lamar-Tanguy, Pascal Cristofini, François Ledru
Large subsets of patients admitted in cardiac rehabilitation centers are having a pacemaker, cardiac resynchronization (CRT) or implantable cardiac defibrillator (ICD). Cardiac rehabilitation for patients, mostly with heart failure, with implanted electronic devices as pacemakers or ICD is a unique opportunity not only to optimize the medical treatment, to increase their exercise capacity and improves their clinical condition but also to supervise the correct functioning of the device. CRT reduces clinical symptoms and increases slightly the exercise capacity...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27672428/delaying-surgery-after-neoadjuvant-chemoradiotherapy-improves-prognosis-of-rectal-cancer
#19
Mehmet Mihmanlı, Esin Kabul Gürbulak, İsmail Ethem Akgün, Mustafa Fevzi Celayir, Pınar Yazıcı, Deniz Tunçel, Tuba Tülin Bek, Ayhan Öz, Sinan Ömeroğlu
AIM: To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy (CRT) and surgery in locally advanced rectal cancer. METHODS: We evaluated 87 patients with locally advanced mid- or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at Şişli Hamidiye Etfal Training and Research Hospital, Istanbul between January 2009 and January 2014. Patients were divided into two groups according to the interval before surgery: < 8 wk (group I) and ≥ 8 wk (group II)...
September 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27632546/fostering-self-awareness-in-collaborative-reflective-training-commentary-response
#20
Barbara Couden Hernandez, Lana Kim, Adrian Lavery, T Kent Denmark
Replies to comments by DeCaporale-Ryan, Dadiz, and Peyre (see record 2016-27364-002) on the original article by Kim, Hernandez, Lavery, and Denmark (see record 2016-18380-001). The current authors thank DeCaporale-Ryan, Dadiz, and Peyre for presenting a rich theoretical counterpoint to their article and respond to issues they raised regarding their collaborative reflecting team (CRT) model.
September 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
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