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https://www.readbyqxmd.com/read/28423430/bioactivity-of-novel-botanical-insecticide-from-gnidia-kaussiana-thymeleaceae-against-callosobruchus-maculatus-coleoptera-chrysomelidae-in-stored-vigna-subterranea-fabaceae-grains
#1
D Kosini, E N Nukenine
Hexane, acetone, and methanol extracts from Gnidia kaussiana Meisn (Thymeleaceae), each at two dosages (0.2 and 1 ml/50 g grains corresponding, respectively to 1 and 5g/kg), and neem seed oil (NSO), used as standard insecticide were evaluated for repellence, toxicity to Callosobruchus maculatus (F.) (Coleoptera: Chrysomelidae) adults, F1 progeny inhibition, persistence and as grain protectant during storage. Experiments were laid out at complete randomized design with five replications for repellence test and four for others...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28419927/synthesis-and-evaluation-of-anti-plasmodial-and-cytotoxic-activities-of-epoxyazadiradione-derivatives
#2
P Ashok Yadav, Ch Pavan Kumar, Bandi Siva, K Suresh Babu, Aparna Devi Allanki, Puran Singh Sijwali, Nishant Jain, A Veerabhadra Rao
Epoxyazadiradione (1), a major compound derived from Neem oil, showed modest anti-plasmodial activity against CQ-resistant and CQ-sensitive strains of the most virulent human malaria parasite P. falciparum. A series of analogues were synthesized by modification of the key structural moieties of this high yield natural product. Out of the library of all compounds tested, compounds 3c and 3g have showed modest anti-plasmodial activity against CQ-sensitive (IC50 2.8 ± 0.29 μM and 1.5 ± 0.01 μM) and CQ-resistant strains (IC50 1...
April 13, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28414726/neem-leaf-glycoprotein-prevents-post-surgical-sarcoma-recurrence-in-swiss-mice-by-differentially-regulating-cytotoxic-t-and-myeloid-derived-suppressor-cells
#3
Madhurima Sarkar, Sarbari Ghosh, Avishek Bhuniya, Tithi Ghosh, Ipsita Guha, Subhasis Barik, Jaydip Biswas, Anamika Bose, Rathindranath Baral
Post-surgical tumor recurrence is a common problem in cancer treatment. In the present study, the role of neem leaf glycoprotein (NLGP), a novel immunomodulator, in prevention of post-surgical recurrence of solid sarcoma was examined. Data suggest that NLGP prevents tumor recurrence after surgical removal of sarcoma in Swiss mice and increases their tumor-free survival time. In NLGP-treated tumor-free mice, increased cytotoxic CD8+ T cells and a decreased population of suppressor cells, especially myeloid-derived suppressor cells (MDSCs) was observed...
2017: PloS One
https://www.readbyqxmd.com/read/28384103/emulsion-of-chloramphenicol-an-overwhelming-approach-for-ocular-delivery
#4
Kalpesh C Ashara, Ketan V Shah
BACKGROUND: Ophthalmic formulations of chloramphenicol have poor bioavailability of chloramphenicol in the ocular cavity. AIM: The present study aimed at exploring the impact of different oil mixtures in the form of emulsion on the permeability of chloramphenicol after ocular application. MATERIALS AND METHODS: Selection of oil mixture and ratio of the components was made by an equilibrium solubility method. An emulsifier was chosen according to its emulsification properties...
March 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28370810/the-effects-of-neem-oil-azadirachta-indica-a-juss-enriched-with-different-concentrations-of-azadirachtin-on-the-integument-of-semi-engorged-rhipicephalus-sanguineus-sensu-lato-acari-ixodidae-females
#5
José Ribamar Lima de Souza, Rafael Neodini Remedio, André Arnosti, Rusleyd Maria Magalhães de Abreu, Maria Izabel Camargo-Mathias
Several studies searching for methods to control Rhipicephalus sanguineus s.l., (dog tick) infestations have been developed aiming to minimize the damages caused by these ectoparasites to the hosts and the environment, which is harmed by the indiscriminate use of toxic acaricide products. In this scenario, neem oil has been used as a natural alternative against ticks, once this chemical has repellent properties and interferes in the growth regulation of these ectoparasites, inhibiting ecdysis. The present study evaluated the effects of azadirachtin-enriched neem oil on the integument of semi-engorged R...
March 29, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28361965/transcriptomics-and-proteomic-studies-reveal-acaricidal-mechanism-of-octadecanoic-acid-3-4-tetrahydrofuran-diester-against-sarcoptes-scabiei-var-cuniculi
#6
Xu Song, Zhenzhen Chen, Renyong Jia, Mei Cao, Yuanfeng Zou, Lixia Li, Xiaoxia Liang, Lizi Yin, Changliang He, Guizhou Yue, Zhongqiong Yin
In our previous study, a new compound, octadecanoic acid-3, 4-tetrahydrofuran diester, possessing potent acaricidal activity was obtained from neem oil. This study performed RNA-seq transcriptomics and iTRAQ proteomics to uncover the acaricidal mechanism of the compound against Sarcoptes scabiei var. cuniculi. The results of transcriptomics indicated that after treatment with octadecanoic acid-3, 4-tetrahydrofuran diester, genes related to "Energy metabolism" were significantly up-/down-regulated, including citrate cycle, oxidative phosphorylation pathway and fatty acid metabolism...
March 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28347172/ultrastructural-changes-in-raillietina-platyhelminthes-cestoda-exposed-to-sulfonoquinovosyldiacylglyceride-sqdg-isolated-from-neem-azadirachta-indica
#7
Anirban Ash, Yogesh P Bharitkar, Sanatan Murmu, Abhijit Hazra, V Ravichandiran, Pradip Kumar Kar, Nirup Bikash Mondal
Neem (Azadirachta indica), has been known to be a curative for various ailments and diseases in the traditional Indian medicinal system from times immemorial. A glycolipid sulfonoquinovosyldiacylglyceride (SQDG) isolated from the leaves of neem has been found to be a proactive antibacterial and antiviral agent in previous studies. The current communication pertains to the anthelmintic activity of SQDG in vitro against a model cestode Raillietina spp. The results of efficacy tests showed a paralysis time of 1...
March 28, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28330106/enhanced-production-of-pectinase-by-aspergillus-terreus-ncft-4269-10-using-banana-peels-as-substrate
#8
Bijay Kumar Sethi, Prativa Kumari Nanda, Santilata Sahoo
Aspergillus terreus NCFT4269.10 was implemented in solid-state (SSF) and liquid static surface fermentation (LSSF) for biosynthesis of pectinase. Amongst various substrates, like, mustard oil cake, neem oil cake, groundnut oil cake, black gram peels, green gram peels, chickling vetch peels/grass pea peels wheat bran, pearl millet residues, finger millet waste, broken rice, banana peels (BP), apple pomace (AP) and orange peels, banana peel (Musa paradisiaca L.; Family: Musaceae) was most suitable for pectinase biosynthesis (LSSF: 400 ± 21...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28319870/topical-application-of-neem-leaves-prevents-wrinkles-formation-in-uvb-exposed-hairless-mice
#9
Hien T T Ngo, Eunson Hwang, Seul-A Seo, Bom Park, Zheng-Wang Sun, Mengyang Zhang, Yu-Kyong Shin, Tae-Hoo Yi
No abstract text is available yet for this article.
March 14, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28296187/lethal-and-sublethal-effects-of-pesticides-in-the-management-of-polyphagotarsonemus-latus-banks-acari-tarsonemidae-on-capsicum-annuum-l
#10
Mariana O Breda, José V Oliveira, Alberto B Esteves Filho, Douglas R S Barbosa, Andrezo A Santos
BACKGROUND: The evaluation of lethal and sublethal effects are of great importance for a complete assessment of the total impact of chemical compounds upon pest populations and the development of management strategies. At this study, the lethal and sublethal effects of different synthetic and botanical products were evaluated upon the broad mite, Polyphagotarsonemus latus (Banks), a major pest of Capsicum annuum L and other crops. RESULTS: Abamectin presented the highest lethal effect to P...
March 15, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28278641/a-new-azadirachta-from-the-crude-extracts-of-neem-azadirachta-indica-a-juss-seeds
#11
Quan Gao, Jia Sun, Hang Xun, Xi Yao, Jin Wang, Feng Tang
One new compound, 2H, 3H-cyclopent[b] furo [2',3':4,5] naphtho [2,4-d] heptlactone-[3,7] furan-6aceticacid, 3-(acetyloxy)-8-(3-furyl)-2a, 4a, 4b, 4c,5,5a, 6, 6a, 8, 9,9a, 10a,10b-13 hydrogen-2a,5a,6a,5-tetramethyl-3-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]-methyl ester, named azadirachta R (1), along with 10 known ones, Azadirachta A, AZ-B, AZ-D, AZ-H, AZ-I, nimbin, deacetylnimbin, salannin, deacetylsalannin and azadiradione were isolated from the crude extracts of neem (Azadirachta indica A. Juss) seeds, which were determined by UV, IR, HR-ESI-MS and NMR data analyses...
February 24, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28246003/in-vitro-evaluation-of-acaricidal-activity-of-novel-green-silver-nanoparticles-against-deltamethrin-resistance-rhipicephalus-boophilus-microplus
#12
B Avinash, R Venu, M Alpha Raj, K Srinivasa Rao, Ch Srilatha, T N V K V Prasad
An investigation was undertaken to study, for the first time, in vitro acaricidal activity of green silver nanoparticles on deltamethrin resistance Rhipicephalus (Boophilus) microplus. The compounds tested were neem coated silver nanoparticles (N-Ag NPs), deltamethrin neem coated silver nanoparticles (DN-Ag NPs), 2, 3 dehydrosalannol (2,3 DHS), 2, 3 DHS coated silver nanoparticles (2, 3-DHS-Ag NPs), Quercetin dihydrate (QDH) and QDH coated silver nanoparticles (QDH-Ag NPs). Also included in this study, for the purpose of comparison, were neem leaf extract (NLE), silver nitrate (AgNO3) and deltamethrin (D)...
February 21, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28242332/synthesis-of-chitosan-incorporated-neem-seed-extract-azadirachta-indica-for-medical-textiles
#13
T Revathi, S Thambidurai
In present study, eco-friendly biosynthesis of Chitosan-Neem seed (CS-NS) composite was prepared by co-precipitation method using aqueous neem seed extract. Cotton fabrics were treated with two different crosslinking agents (Glutaraldehyde and Citric acid) then the synthesized composite coated on cotton fabric by chemical linkage between the composite and the cellulose structure. As synthesized composite materials and treated cotton fabrics were characterized by Fourier transform infrared spectroscopy for functional groups confirmation, X-ray diffraction for crystalline behavior determination, UV-vis spectroscopy analysis for optical property and High resolution scanning electron microscopy for Surface morphological properties...
February 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28221960/mycotoxin-contamination-in-stored-maize-and-groundnuts-based-on-storage-practices-and-conditions-in-subhumid-tropical-africa-the-case-of-kilosa-district-tanzania
#14
K S Magembe, M W Mwatawala, D P Mamiro
Experiments were conducted to assess the influence of storage practices on mycotoxin incidences in stored maize and groundnuts in Kilosa District, Eastern Central Tanzania. Factorial experiments were used to test the effects of processing, storage conditions, and protectants at 3-month intervals for 12 weeks. Temperature and relative humidity data were recorded by using data loggers. The differences among the treatment means were compared using Tukey's honestly significant difference test at 5% probability level...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28209019/efficacy-of-specific-plant-products-on-microorganisms-causing-dental-caries
#15
M Rajini Kanth, A Ravi Prakash, G Sreenath, Vikram Simha Reddy, S Huldah
INTRODUCTION: Dental caries and periodontal diseases are the most common oral diseases seen globally, both in developed and developing countries. Oral microorganisms that is gram positive and gram negative bacteria are known to be involved in causation of these diseases. Nowadays commercially available dentrifices and mouth rinses are known to contain ingredients that can alter the oral microbial flora and have undesirable side effects such as vomiting, diarrhoea, disarrangement of oral, intestinal flora and tooth staining...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28157393/oral-systemic-botanical-agents-for-the-treatment-of-psoriasis-a-review
#16
Benjamin Farahnik, Divya Sharma, Joseph Alban, Raja Sivamani
INTRODUCTION: Patients with psoriasis often use botanical therapies as part of their treatment. It is important for clinicians to be aware of the current evidence regarding these agents as they treat patients. METHODS: A systematic literature search was conducted using the PubMed, MEDLINE, and EMBASE database for randomized clinical trials assessing the use of botanical therapeutics for psoriasis. The search included the following keywords: "psoriasis" and "plant" or "herbal" or "botanical...
February 3, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28143560/insecticidal-effects-of-deltamethrin-in-laboratory-and-field-populations-of-culicoides-species-how-effective-are-host-contact-reduction-methods-in-india
#17
Rien De Keyser, Clare Cassidy, Swathi Laban, Prakash Gopal, John A Pickett, Yarabolu K Reddy, Minakshi Prasad, Gaya Prasad, Sreekumar Chirukandoth, Kandasamy Senthilven, Simon Carpenter, James G Logan
BACKGROUND: Bluetongue virus (BTV) is transmitted by Culicoides biting midges and causes bluetongue (BT), a clinical disease observed primarily in sheep. BT has a detrimental effect on subsistence farmers in India, where hyperendemic outbreaks impact on smallholdings in the southern states of the country. In this study, we establish a reliable method for testing the toxic effects of deltamethrin on Culicoides and then compare deltamethrin with traditional control methods used by farmers in India...
January 31, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28107536/correction-methylation-markers-of-early-stage-non-small-cell-lung-cancer
#18
Kaie Lokk, Tõnu Vooder, Raivo Kolde, Kristjan Välk, Urmo Võsa, Retlav Roosipuu, Lili Milani, Krista Fischer, Marina Koltsina, Egon Urgard, Tarmo Annilo, Andres Metspalu, Neeme Tõnisson
[This corrects the article DOI: 10.1371/journal.pone.0039813.].
2017: PloS One
https://www.readbyqxmd.com/read/28101834/management-of-acute-skin-toxicity-with-hypericum-perforatum-and-neem-oil-during-platinum-based-concurrent-chemo-radiation-in-head-and-neck-cancer-patients
#19
Pierfrancesco Franco, Monica Rampino, Oliviero Ostellino, Marina Schena, Giancarlo Pecorari, Paolo Garzino Demo, Massimo Fasolis, Francesca Arcadipane, Stefania Martini, Chiara Cavallin, Mario Airoldi, Umberto Ricardi
Acute skin toxicity is a frequent finding during combined radiotherapy and chemotherapy in head and neck cancer patients. Its timely and appropriate management is crucial for both oncological results and patient's global quality of life. We herein report clinical data on the use of Hypericum perforatum and neem oil in the treatment of acute skin toxicity during concurrent chemo-radiation for head and neck cancer. A consecutive series of 50 head and neck cancer patients undergoing concomitant radio-chemotherapy with weekly cisplatin was analyzed...
February 2017: Medical Oncology
https://www.readbyqxmd.com/read/28100884/stabilization-of-neem-oil-biodiesel-with-corn-silk-extract-during-long-term-storage
#20
Rehab Farouk M Ali, Ayman M El-Anany
The current study aimed to evaluate the antioxidant efficiency of different extracts of corn silk. In addition, the impact of corn silk extract on oxidative stability of neem biodiesel during storage was studied. The highest phenolics, DPPH radical scavenging and reducing power activities were recorded for methanol-water extract. The longest oxidation stability (10 h) was observed for biodiesel samples blended with 1000 ppm of corn silk extract (CSE). At the end of storage period the induction time of biodiesel samples mixed with 1000 ppm of CSE or butylated hydroxytoluene (BHT) were about 6...
February 1, 2017: Journal of Oleo Science
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