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https://www.readbyqxmd.com/read/29116538/environmentally-benign-nanometric-neem-laced-urea-emulsion-for-controlling-mosquito-population-in-environment
#1
Prabhakar Mishra, Merlyn Keziah Samuel, Ruchishya Reddy, Brij Kishore Tyagi, Amitava Mukherjee, Natarajan Chandrasekaran
The increasing risk of vector-borne diseases and the environmental pollution in the day-to-day life due to the usage of the conventional pesticides makes the role of nanotechnology to come into the action. The current study deals with one of the applications of nanotechnology through the formulation of neem urea nanoemulsion (NUNE). NUNE was formulated using neem oil, Tween 20, and urea using the microfluidization method. Prior to the development of nanoemulsion, the ratio of oil/surfactant/urea was optimized using the response surface modeling method...
November 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29104390/an-in-vitro-comparative-evaluation-of-efficacy-of-disinfecting-ability-of-garlic-oil-neem-oil-clove-oil-and-tulsi-oil-with-autoclaving-on-endodontic-k-files-tested-against-enterococcus-faecalis
#2
Shivayogi Hugar, Punit M Patel, Jyoti Nagmoti, Chaitanya Uppin, Laresh Mistry, Neha Dhariwal
Aim: To comparatively evaluate the efficacy of disinfecting ability of garlic oil, neem oil, clove oil, and tulsi oil with autoclaving on endodontic K files tested against Enterococcus faecalis. Materials and methods: Fifty endodontic K files were exposed to the test micro-organism and checked for its disinfecting ability using three different methods. Result: Garlic oil, clove oil, tulsi oil and autoclave showed considerable effectiveness against E...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29074140/airborne-allergic-contact-dermatitis-caused-by-neem-oil
#3
A Sánchez-Gilo, A Nuño González, M Gutiérrez Pascual, F J Vicente Martín
No abstract text is available yet for this article.
October 23, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29059091/contact-allergy-to-neem-oil
#4
Anton de Groot, Berend A Jagtman, Marjolijn Woutersen
A case of allergic contact dermatitis from neem oil is presented. Neem oil (synonyms: Melia azadirachta seed oil [INCI name], nim oil, margosa oil) is a vegetable (fixed) oil obtained from the seed of the neem tree Azadirachta indica by cold pressing. Contact allergy to neem oil has been described previously in only 3 patients. The allergen(s) is/are unknown.
November 2017: Dermatitis
https://www.readbyqxmd.com/read/29044755/epoxyazadiradione-purified-from-the-azadirachta-indica-seed-induced-mitochondrial-apoptosis-and-inhibition-of-nf%C3%AE%C2%BAb-nuclear-translocation-in-human-cervical-cancer-cells
#5
G Shilpa, J Renjitha, R Saranga, Francis K Sajin, Mangalam S Nair, Beena Joy, B S Sasidhar, S Priya
Epoxyazadiradione (EAD) is an important limonoid present in Neem (Azadirachta indica) plant. In the present study, we have purified EAD from Neem seed and studied its anticancer potential in human cervical cancer (HeLa) cells. Cell proliferation inhibition studies indicated that the GI50 value of EAD is 7.5 ± 0.0092 μM in HeLa cells, whereas up to 50 μM concentrations EAD did not affect the growth of normal H9C2 cells. The control drug cisplatin inhibited the growth of both HeLa and H9C2 cells with a GI50 value of 2...
October 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29039495/protective-effects-of-neem-azadirachta-indica-a-juss-leaf-extract-against-cigarette-smoke-and-lipopolysaccharide-induced-pulmonary-inflammation
#6
Jae-Won Lee, Hyung Won Ryu, So-Yeon Park, Hyun Ah Park, Ok-Kyoung Kwon, Heung Joo Yuk, Krishna K Shrestha, Minwoo Park, Jung Hee Kim, Sangwoo Lee, Sei-Ryang Oh, Kyung-Seop Ahn
Neem (Azadirachta indica A. Juss.) leaf has been reported to exert anti-inflammatory, antibacterial and antioxidant effects. The purpose of this study was to investigate the protective effects of neem leaf extract (NLE) against cigarette smoke (CS)- and lipopolysaccharide (LPS)-induced pulmonary inflammation. Treatment with NLE significantly attenuated the infiltration of inflammatory cells, such as neutrophils and macrophages in bronchoalveolar lavage fluid (BALF). NLE also reduced the production of reactive oxygen species and the activity of neutrophil elastase in BALF...
October 10, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28976900/nuts-and-bolts-of-oil-and-temperature-in-topical-preparations-of-salicylic-acid
#7
Kalpesh C Ashara, Ketan V Shah
BACKGROUND: Traditional formulations of salicylic acid in ointment bases have disadvantages of being greasy and irritant due to free crystals. AIM: To explore the method for selection of oils and their ratio for topical preparation on the basis of equilibrium solubility study of salicylic acid and to evaluate temperature effect. MATERIALS AND METHODS: Scanning and calibration curve of salicylic acid in methanol were developed. Among available oils, those that had no interference of absorbance of salicylic acid were short-listed for screening purpose...
September 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28965841/corrigendum-to-topical-application-of-neem-leaves-prevents-wrinkles-formation-in-uvb-exposed-hairless-mice-j-photochem-photobiol-b-biol-169-april-2017-161-170
#8
Hien T T Ngo, Eunson Hwang, Seul-A Seo, Bom Park, Zheng-Wang Sun, Mengyang Zhang, Yu-Kyong Shin, Tae-Hoo Yi
No abstract text is available yet for this article.
September 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28965424/neem-oil-nanoemulsions-characterisation-and-antioxidant-activity
#9
Federica Rinaldi, Patrizia Nadia Hanieh, Catia Longhi, Simone Carradori, Daniela Secci, Gokhan Zengin, Maria Grazia Ammendolia, Elena Mattia, Elena Del Favero, Carlotta Marianecci, Maria Carafa
The aim of the present work is to develop nanoemulsions (NEs), nanosized emulsions, manufactured for improving the delivery of active pharmaceutical ingredients. In particular, nanoemulsions composed of Neem seed oil, contain rich bioactive components, and Tween 20 as nonionic surfactant were prepared. A mean droplet size ranging from 10 to 100 nm was obtained by modulating the oil/surfactant ratio. Physicochemical characterisation was carried out evaluating size, ζ-potential, microviscosity, polarity and turbidity of the external shell and morphology, along with stability in simulated cerebrospinal fluid (CSF), activity of Neem oil alone and in NEs, HEp-2 cell interaction and cytotoxicity studies...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28960316/genome-wide-association-study-and-meta-analysis-in-northern-european-populations-replicate-multiple-colorectal-cancer-risk-loci
#10
Tomas Tanskanen, Linda van den Berg, Niko Välimäki, Mervi Aavikko, Eivind Ness-Jensen, Kristian Hveem, Yvonne Wettergren, Elinor Bexe Lindskog, Neeme Tõnisson, Andres Metspalu, Kaisa Silander, Giulia Orlando, Philip J Law, Sari Tuupanen, Alexandra E Gylfe, Ulrika A Hänninen, Tatiana Cajuso, Johanna Kondelin, Antti-Pekka Sarin, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, Heikki Järvinen, Laura Renkonen-Sinisalo, Anna Lepistö, Jan Böhm, Jukka-Pekka Mecklin, Nada A Al-Tassan, Claire Palles, Lynn Martin, Ella Barclay, Albert Tenesa, Susan M Farrington, Maria N Timofeeva, Brian F Meyer, Salma M Wakil, Harry Campbell, Christopher G Smith, Shelley Idziaszczyk, Tim S Maughan, Richard Kaplan, Rachel Kerr, David Kerr, Daniel D Buchanan, Aung K Win, John Hopper, Mark A Jenkins, Polly A Newcomb, Steve Gallinger, David Conti, Fredrick R Schumacher, Graham Casey, Jeremy P Cheadle, Malcolm G Dunlop, Ian P Tomlinson, Richard S Houlston, Kimmo Palin, Lauri A Aaltonen
Genome-wide association studies have been successful in elucidating the genetic basis of colorectal cancer (CRC), but there remains unexplained variability in genetic risk. To identify new risk variants and to confirm reported associations, we conducted a genome-wide association study in 1,701 CRC cases and 14,082 cancer-free controls from the Finnish population. A total of 9,068,015 genetic variants were imputed and tested, and 30 promising variants were studied in additional 11,647 cases and 12,356 controls of European ancestry...
September 28, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28953894/comparative-role-of-neem-seed-extract-moringa-leaf-extract-and-imidacloprid-in-the-management-of-wheat-aphids-in-relation-to-yield-losses-in-pakistan
#11
COMPARATIVE STUDY
Farhan Mahmood Shah, Muhammad Razaq, Abid Ali, Peng Han, Julian Chen
Wheat being staple food of Pakistan is constantly attacked by major wheat aphid species, Schizaphis graminum (R.), Rhopalosiphum padi (L.) and Sitobion avenae (F.). Due to concern on synthetic chemical use in wheat, it is imperative to search for alternative environment- and human- friendly control measures such as botanical pesticides. In the present study, we evaluated the comparative role of neem seed extract (NSE), moringa leaf extract (MLE) and imidacloprid (I) in the management of the aphid as well as the yield losses parameters in late planted wheat fields...
2017: PloS One
https://www.readbyqxmd.com/read/28899496/neem-azadirachta-indica-an-indian-traditional-panacea-with-modern-molecular-basis
#12
REVIEW
Subash Chandra Gupta, Sahdeo Prasad, Amit K Tyagi, Ajaikumar B Kunnumakkara, Bharat B Aggarwal
BACKGROUND: For centuries, agents derived from natural sources (mother nature), especially plants have been the primary source of medicine. Neem, also referred to as Azadirachta indica is one such plant that has been so named because it provides freedom from all diseases, and used for thousands of years in Indian and African continents. Different parts of the plant including flowers, leaves, seeds and bark have been used to treat both acute and chronic human diseases; and used as insecticide; antimicrobial, larvicidal, antimalarial, antibacterial, antiviral, and spermicidal...
October 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28860055/novel-and-environmental-friendly-approach-impact-of-neem-azadirachta-indica-gum-nano-formulation-ngnf-on-helicoverpa-armigera-hub-and-spodoptera-litura-fab
#13
Chinnaperumal Kamaraj, Pachiyappan Rajiv Gandhi, Gandhi Elango, Sengodan Karthi, Ill-Min Chung, Govindsamy Rajakumar
The future of this study was to prepare a natural pesticide which will not harm the environment and yet control pests. Neem gum nano formulation (NGNF), a novel biopesticide prepared from the Neem gum extract (Azadirachta indica) (NGE) was evaluated for its antifeedant, larvicidal and pupicidal activities against Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.) at 100ppm. The NGNF showed significant (100%) antifeedant, larvicidal and pupicidal activities against H. armigera and S. litura. The LC50 values of 10...
August 28, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28843234/neem-seed-oil-induces-apoptosis-in-mcf-7-and-mda-mb-231-human-breast-cancer-cells
#14
Ramesh Sharma, Shweta Kaushik, Hari Shyam, Satish Agarwal, Anil Kumar Balapure
Background: In traditional Indian medicine, azadirachta indica (neem) is known for its wide range of medicinal properties. Various parts of neem tree including its fruit, seed, bark, leaves, and root have been shown to possess antiseptic, antiviral, antipyretic, anti-inflammatory, antiulcer, antimalarial, antifungal and anticancer activity. Materials and Methods: MCF-7 and MDA MB-231 cells were exposed to various concentrations of 2% ethanolic solution of NSO (1-30 μl/ml) and further processed for cell viability, cell cycle and apoptosis analysis...
August 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28797303/combined-antioxidant-effects-of-neem-extract-bacteria-red-blood-cells-and-lysozyme-possible-relation-to-periodontal-disease
#15
Leali Heyman, Yael Houri-Haddad, Samuel N Heyman, Isaac Ginsburg, Yossi Gleitman, Osnat Feuerstein
BACKGROUND: The common usage of chewing sticks prepared from Neem tree (Azadirachta indica) in India suggests its potential efficacy in periodontal diseases. The objective of this study is to explore the antibacterial effects of Neem leaf extract on the periodontophatic bacteria Porphyromonas gingivalis and Fusobacterium nucleatum, and its antioxidant capacities alone and in combination with bacteria and polycationic peptides that may be at the site of inflammation. METHODS: Neem leaf extract was prepared by ethanol extraction...
August 10, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28794932/screening-of-neem-extracts-for-microbial-anti-chaperone-activity-by-employing-in-vitro-enzyme-refolding-assay
#16
Jyoti M Patki, Priyanka Shah
Microbial heat shock proteins (Hsps) play an important role in pathogenesis and development of resistance to existing drugs. New compounds that target microbial molecular chaperones have the potential of combating the challenge of anti-microbial resistance. The present study was aimed at assessing the employment of in vitro enzyme refolding assay to detect anti-chaperone activity of Neem (Azadirachta indica) extracts. Protein extracts of thermotolerant Escherichia coli cells were used as a source of Hsps or chaperones...
October 2017: 3 Biotech
https://www.readbyqxmd.com/read/28755695/preimaginal-exposure-to-azadirachtin-affects-food-selection-and-digestive-enzymes-in-adults-of-drosophila-melanogaster-diptera-drosophilidae
#17
Samira Kilani-Morakchi, Radia Bezzar-Bendjazia, Maroua Ferdenache, Nadia Aribi
Among the plant derived product, azadirachtin, a neem-based insecticide, is exceptional in having a broad range of bioactivity including toxicity, growth, development and reproduction effects, repellency and antifeedancy. If considerable progress on the physiological and biological activities and agricultural application of azadirachtin has been achieved, its exact mechanism of action remains uncertain. In this study, we aimed at assessing the lethal and sublethal behavioral and physiological effects of azadirachtin on Drosophila melanogaster Meigen, 1830 (Diptera: Drosophilidae) as biological model...
August 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28746375/reduced-dosage-of-the-chromosome-axis-factor-red1-selectively-disrupts-the-meiotic-recombination-checkpoint-in-saccharomyces-cerevisiae
#18
Tovah E Markowitz, Daniel Suarez, Hannah G Blitzblau, Neem J Patel, Andrew L Markhard, Amy J MacQueen, Andreas Hochwagen
Meiotic chromosomes assemble characteristic "axial element" structures that are essential for fertility and provide the chromosomal context for meiotic recombination, synapsis and checkpoint signaling. Whether these meiotic processes are equally dependent on axial element integrity has remained unclear. Here, we investigated this question in S. cerevisiae using the putative condensin allele ycs4S. We show that the severe axial element assembly defects of this allele are explained by a linked mutation in the promoter of the major axial element gene RED1 that reduces Red1 protein levels to 20-25% of wild type...
July 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28736861/azadirachtin-effects-on-mating-success-gametic-abnormalities-and-progeny-survival-in-drosophila-melanogaster-diptera
#19
Chemseddine M Oulhaci, Béatrice Denis, Samira Kilani-Morakchi, Jean-Christophe Sandoz, Laure Kaiser, Dominique Joly, Nadia Aribi
BACKGROUND: Azadirachtin is a prominent natural pesticide and represents an alternative to conventional insecticides. It has been successfully used against insect pests. However, its effects on reproduction require further analysis. Here we investigated lethal and sublethal effects of azadirachtin, on treated adults in a model insect, Drosophila melanogaster (Meigen). Dose-mortality relationships as well as several parameters of reproduction (mating, spermatogenesis, oogenesis and fertility) were examined...
July 24, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28729800/dentition-status-and-treatment-needs-of-human-immunodeficiency-virus-positive-patients-on-anti-retro-viral-therapy-in-raichur-taluk-karnataka-india-a-cross-sectional-study
#20
Shrikanth Muralidharan, Arunkumar Acharya, Shanthi Margabandhu
OBJECTIVE: The aim of the study was to assess the dentition status and the treatment needs of the HIV-positive patients on ART for more than a year in Raichur, Karnataka. MATERIALS AND METHODS: Convenience sampling was followed. The sample size was 170. The dentition status and treatment needs of the patients were recorded as per the WHO guidelines. RESULTS: The overall prevalence of dental caries was 79.4%. Males had higher percentage of dental caries than the females, and this was found to be statistically significant...
April 2017: European Journal of Dentistry
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