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https://www.readbyqxmd.com/read/28213930/antibiotic-administration-alleviates-the-aggravating-effect-of-orthodontic-force-on-ligature-induced-experimental-periodontitis-bone-loss-in-mice
#1
J Shi, Z Liu, T Kawai, Y Zhou, X Han
BACKGROUND AND OBJECTIVES: It is recognized that orthodontic force (OF) has an aggravating effect on the progression of destructive periodontitis if periodontitis have not been well controlled. However, the underlying mechanism is not completely clear. This study was to investigate the effect of antibiotic administration on OF-aggravated, ligature-induced experimental periodontitis in mice. MATERIAL AND METHODS: C57BL/6 mice (male, 8 wk old) were divided into three groups (n = 8)...
February 18, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28213764/presence-of-root-canal-treatment-has-no-influence-on-periodontal-bone-loss
#2
Fabiola-Regina Rodriguez, Nadine Paganoni, Peter Eickholz, Roland Weiger, Clemens Walter
AIM: The aim of this study was to compare the interproximal bone level at root canal-filled teeth and non-root canal-filled teeth. MATERIALS AND METHODS: The records of patients from the department were consecutively screened from January 2009 to October 2011. The distance between the coronal reference point to the alveolar bone crest (AC) was assessed at the mesial and distal aspects of root canal-filled teeth (RCF+) and their contralateral non-root canal-filled teeth (RCF-) on periapical radiographs...
February 17, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28212665/clinical-outcome-of-periodontal-regenerative-therapy-using-collagen-membrane-and-deproteinized-bovine-bone-mineral-a-2-5-year-follow-up-study
#3
Daisuke Irokawa, Takahiro Takeuchi, Katsuya Noda, Hiroaki Goto, Masahiro Egawa, Sachiyo Tomita, Hiroki Sugito, Masahiko Nikaido, Atsushi Saito
BACKGROUND: This study aimed to evaluate, longitudinally, the outcome of periodontal regenerative therapy using a deproteinized bovine bone mineral (DBBM) in combination with a collagen barrier (CB) for the treatment of intrabony defects. RESULTS: Patients with chronic periodontitis who have completed initial periodontal therapy participated in this study. They had at least one 2- or 3-wall intrabony periodontal defect of ≥3 mm in depth. During surgery, defects were filled with DBBM and covered with CB...
February 17, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28212615/molecular-pathways-underlying-inhibitory-effect-of-antimicrobial-peptide-nal-p-113-on-bacteria-biofilms-formation-of-porphyromonas-gingivalis-w83-by-dna-microarray
#4
Hong-Yan Wang, Li Lin, Li-Si Tan, Hui-Yuan Yu, Jya-Wei Cheng, Ya-Ping Pan
BACKGROUND: Wound-related infection remains a major challenge for health professionals. One disadvantage in conventional antibiotics is their inability to penetrate biofilms, the main protective strategy for bacteria to evade irradiation. Previously, we have shown that synthetic antimicrobial peptides could inhibit bacterial biofilms formation. RESULTS: In this study, we first delineated how Nal-P-113, a novel antimicrobial peptide, exerted its inhibitory effects on Porphyromonas gingivalis W83 biofilms formation at a low concentration...
February 17, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28212613/porphyromonas-gingivalis-can-invade-periodontal-ligament-stem-cells
#5
Chunling Pan, Junchao Liu, Hongyan Wang, Jia Song, Lisi Tan, Haijiao Zhao
BACKGROUND: Porphyromonas gingivalis is strongly associated with the development, progression, severity and recurrence of periodontitis. Periodontal ligament stem cells (PDLSCs) play an important role in the maintenance of periodontal tissue self-renewal and repair. The purpose of this study was to investigate the ability of P. gingivalis to infect PDLSCs using an in vitro monolayer model. METHODS: We separated and cultured primary PDLSCs using the tissue block with limiting dilution method...
February 17, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28212454/clinical-comparison-of-screw-retained-and-screwless-morse-taper-implant-abutment-connections-one-year-postloading-results
#6
Esma Geckili, Onur Geckili, Hakan Bilhan, Omer Kutay, Tayfun Bilgin
PURPOSE: The purpose of this study was to clinically evaluate the screwless Morse taper implant-abutment connection type, in which the retention screw is totally eliminated, in terms of stability, success, periodontal parameters, and marginal bone levels after 1 year of function by comparing it with a passive fit internal implant-abutment connection, wherein a space exists between the matching components. MATERIALS AND METHODS: Each edentulous subject received an implant with a screwless Morse taper connection (MT) in the left canine area of the mandible and an implant with a screw-retained implant-abutment connection (SR) in the right canine area of the mandible...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28211083/the-association-between-periodontitis-and-sleep-duration
#7
Mario Romandini, Gioele Gioco, Giorgio Perfetti, Giorgio Deli, Edoardo Staderini, Andreina Laforì
AIM: Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis. The aim of this cross-sectional study was to evaluate if there was in 2012 an association between periodontitis and sleep duration in a representative sample of the South Korean population. MATERIALS AND METHODS: A total of 5,812 subjects representative of 39.4 million of adults were examined...
February 17, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28210435/role-of-thr399ile-and-asp299gly-polymorphisms-of-toll-like-receptor-4-gene-in-acute-dental-abscess
#8
Ebrahim Miri-Moghaddam, Narges Farhad-Mollashahi, Elnaz Baghaee, Ali Bazi, Yasaman Garme
BACKGROUND: Apical Periodontitis (AP) is an inflammatory disease that affects the tissues surrounding the root end of a tooth. The disease which is caused by endodontic infections presents in different clinical ways including development of an acute abscess. Recent studies have provided information suggesting role of a multitude of factors in pathogenesis of acute apical abscess (AAA). In this case-control study, our goal was to evaluate the frequency and potential role of two common polymorphisms of toll like receptor-4 (TLR-4) gene; Thr399Ile (1196 C>T) and Asp299Gly (+896 A>G), in 50 patients with AAA as cases and 50 patients with asymptomatic apical periodontitis (AAP) as controls...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210431/vertical-root-fracture-resistance-of-simulated-immature-permanent-teeth-filled-with-mta-using-different-vehicles
#9
Hacer Aksel, Sevinc Askerbeyli-Örs, Derya Deniz-Sungur
BACKGROUND: The aim of the study is to evaluate the resistance vertical root fracture (VRF) of mineral trioxide aggregate (MTA) filled-immature permanent roots by using three different vehicles. MATERIAL AND METHODS: Forty-extracted human single-rooted mandibular premolars were selected and the root length was standardized to the length of 9 mm. For simulation of immature tooth apices, peeso reamers were introduced into the root canals and the prepared roots were assigned into three experimental groups according the used vehicle (distilled water-DW, prophylene glycol-PG, chlorhexidine-CHX) and control group (n=10)...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28209360/levels-of-high-mobility-group-box-1-in-gingival-crevicular-fluid-in-nonsmokers-and-smokers-with-chronic-periodontitis
#10
Yi-Chun Lin, Ching-Yi Wu, Lien-Yu Chang, Ching-Chu Chen, Hsuan-Hung Chen, Yu-Lin Lai, Shan-Ling Hung
BACKGROUND/PURPOSE: High-mobility group box-1 (HMGB1), a proinflammatory cytokine, plays a role in inflammatory disorders. Smoking is a well-established risk factor for periodontal disease. The aim of this study was to compare the levels of HMGB1 in the gingival crevicular fluid from periodontally healthy nonsmokers, chronic periodontitis nonsmokers, and chronic periodontitis smokers. Furthermore, the relationship between levels of HMGB1 and periodontal parameters was examined. METHODS: Periodontal parameters of 17 nonsmokers with chronic periodontitis, nine smokers with chronic periodontitis, and nine periodontally healthy nonsmokers were examined...
February 13, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28209019/efficacy-of-specific-plant-products-on-microorganisms-causing-dental-caries
#11
M Rajini Kanth, A Ravi Prakash, G Sreenath, Vikram Simha Reddy, S Huldah
INTRODUCTION: Dental caries and periodontal diseases are the most common oral diseases seen globally, both in developed and developing countries. Oral microorganisms that is gram positive and gram negative bacteria are known to be involved in causation of these diseases. Nowadays commercially available dentrifices and mouth rinses are known to contain ingredients that can alter the oral microbial flora and have undesirable side effects such as vomiting, diarrhoea, disarrangement of oral, intestinal flora and tooth staining...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28209007/cognitive-ability-as-a-determinant-of-socioeconomic-and-oral-health-status-among-adolescent-college-students-of-bengaluru-india
#12
Rekha Rao Karnam, Naganandini Samapth Kumar, Shruthi Eshwar, Shravani Deolia
INTRODUCTION: Levels of oral health and economic status are unequally distributed throughout the population. Inequality has multiple causes and that the effect of Socio Economic Status (SES) and demographic factors, on oral health is mediated through several factors. Association between cognitive ability and oral health had been demonstrated in older age groups but adolescents and younger adults have received relatively little attention in this field. AIM: To establish the role of cognitive ability as a determinant of SES and oral health status among adolescent college students of Benagluru, Karnataka, India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28209006/a-comparative-evaluation-of-serum-magnesium-in-diabetes-mellitus-type-2-patients-with-and-without-periodontitis-a-clinico-biochemical-study
#13
Akshatha Shetty, Rahul Bhandary, Biju Thomas, Amitha Ramesh
INTRODUCTION: Magnesium is an essential cation playing a crucial role in many physiological functions and its imbalance is associated with greater number of pathological situations. Oxidative stress is usually increased due to decreased essential nutrients. Hence, any imbalance of essential nutrients like serum magnesium can significantly play a role in the pathobiology of periodontitis in the presence of diabetes, as diabetes and chronic periodontitis are two chronic diseases that have been biologically linked...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208999/experience-from-classroom-teaching-to-clinical-practice-regarding-shortened-dental-arch-sda-concept-among-dentists-a-questionnaire-study
#14
Ritu Gupta, Ravneet Malhi, Basavaraj Patthi, Ashish Singla, Chandrasheker Janakiram, Venisha Pandita, Monika Prasad, Jishnu Krishna Kumar
INTRODUCTION: Periodontal disease and dental caries are the common oral conditions which cause loss of teeth, mostly molars. This further leads to Shortening of Dental Arch and Shortened Dental Arch (SDA) concept provides the overall requirements of functional dentition at reduced cost without compromising the health. AIM: The aim of the present study was to assess the Knowledge, Attitude and Practices (KAP) towards SDA concept among dentists of Ghaziabad city (Uttar Pradesh, India)...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208578/role-of-cortico-cancellous-heterologous-bone-in-human-periodontal-ligament-stem-cell-xeno-free-culture-studied-by-synchrotron-radiation-phase-contrast-microtomography
#15
Serena Mazzoni, Sara Mohammadi, Giuliana Tromba, Francesca Diomede, Adriano Piattelli, Oriana Trubiani, Alessandra Giuliani
This study was designed to quantitatively demonstrate via three-dimensional (3D) images, through the Synchrotron Radiation Phase-Contrast Microtomography (SR-PhC-MicroCT), the osteoinductive properties of a cortico-cancellous scaffold (Osteobiol Dual Block-DB) cultured with human Periodontal Ligament Stem Cells (hPDLSCs) in xeno-free media. In vitro cultures of hPDLSCs, obtained from alveolar crest and horizontal fibers of the periodontal ligament, were seeded onto DB scaffolds and cultured in xeno-free media for three weeks...
February 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28208234/the-influence-of-traumatic-occlusion-on-the-repair-process-for-teeth-following-subluxation
#16
Marina Fuzette Amaral, Caio Vinicius Lourenço Debortoli, Wilson Roberto Poi, Sônia Regina Panzarini, Daniela Atili Brandini
BACKGROUND/AIM: Traumatic occlusion can cause morphofunctional alterations that interfere in the homeostasis of the periodontium The aim of this study was to assess the influence of traumatic occlusion (TO) on the periodontal repair process for teeth following subluxation. MATERIALS AND METHODS: Ninety Wistar rats aged 12 weeks were divided into three groups: control (C), subluxation (S) and subluxation with traumatic occlusion (S+TO). Subluxation was created with an impact force of 900 cN applied by a tensiometer and TO was created with a direct composite resin filling...
February 16, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28208029/l1-peptide-conjugated-fibrin-hydrogels-promote-salivary-gland-regeneration
#17
K Nam, C-S Wang, C L M Maruyama, P Lei, S T Andreadis, O J Baker
Hyposalivation contributes to dental caries, periodontitis, and microbial infections. Additionally, it impairs activities of daily living (e.g., speaking, chewing, and swallowing). Treatments for hyposalivation are currently limited to medications (e.g., the muscarinic receptor agonists pilocarpine and cevimeline) that induce saliva secretion from residual acinar cells and the use of saliva substitutes. However, given that these therapies provide only temporary relief, the development of alternative treatments to restore gland function is essential...
February 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28207944/relationship-between-renal-function-and-periodontal-disease-in-community-dwelling-elderly-women-with-different-genotypes
#18
Akihiro Yoshihara, Noriko Sugita, Masanori Iwasaki, Yanming Wang, Hideo Miyazaki, Hiromasa Yoshie, Kazutoshi Nakamura
OBJECTIVES: The aim of this study was to examine the association between periodontal disease and renal function in elderly women with different genotypes. MATERIAL AND METHODS: A total of 332 postmenopausal never-smoking women were analyzed. Poor renal function was defined as serum cystatin C >0.91 mg/L. Periodontal disease markers such as periodontal inflamed surface area (PISA) were evaluated. Selected variables, including PISA quartile, body mass index (BMI), HbA1C and age in Arg allele carriers and non-carriers based on the beta-3 adrenergic receptor, or between Ala allele carriers and non-carriers based on peroxisome proliferator-activated receptor gamma, were analyzed using multiple logistic regression analysis...
February 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28207941/mfg-e8-inhibits-periodontitis-in-non-human-primates-and-its-gingival-crevicular-fluid-levels-can-differentiate-periodontal-health-from-disease-in-humans
#19
Tetsuhiro Kajikawa, Fatimah Meshikhes, Tomoki Maekawa, Evlambia Hajishengallis, Kavita B Hosur, Toshiharu Abe, Kevin Moss, Triantafyllos Chavakis, George Hajishengallis
AIM: We have previously shown that the secreted glycoprotein MFG-E8 has anti-inflammatory and anti-osteoclastogenic properties. Our objective was to investigate the potential of MFG-E8 as a diagnostic or therapeutic agent in periodontitis. MATERIALS AND METHODS: Periodontitis was induced in non-human primates (NHPs) by placing ligatures around posterior teeth on both halves of the mandible for a split-mouth design: one side was treated with MFG-E8-Fc and the other with Fc control...
February 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28207939/chemokine-in-inflamed-periodontal-tissues-activates-healthy-periodontal-ligament-stem-cell-migration
#20
Jung-Seok Lee, Jong-Bin Lee, Jae-Kook Cha, Eun-Young Choi, So-Yon Park, Kyoo-Sung Cho, Chang-Sung Kim
AIM: The present study aimed to characterize the expression pattern of chemokines obtained from inflamed periodontal defects and to determine the characteristics of human periodontal-ligament stem cells (hPDLSCs) migrated by each specific chemokine. MATERIALS AND METHODS: Both inflamed and healthy periodontal tissues were obtained from periodontitis patients (n=11), and the chemokine expression levels were analyzed. The periodontal-tissue-specific chemokines were applied to healthy hPDLSCs from extracted teeth (n=3), with FGF-2 acting as a positive control...
February 16, 2017: Journal of Clinical Periodontology
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