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interval colorectal cancer

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https://www.readbyqxmd.com/read/28323443/impact-of-abdominal-adipose-depots-and-race-on-risk-for-colorectal-cancer-a-case-control-study
#1
Sandra L Gomez-Perez, Vivek Chaudhry, Winnie Mar, Bimal Patel, Giamila Fantuzzi, Sally Freels, Carol A Braunschweig
Visceral adipose tissue (VAT) but not subcutaneous adipose tissue (SAT) is associated with obesity-related diseases including colorectal cancer (CRC). Superficial SAT (SSAT) and deep SAT (DSAT), components of SAT, also appear to independently influence disease risk. These abdominal adipose tissues (AATs) are not extensively studied in connection with CRC and have not been explored in the United States despite known racial variations in body composition. We conducted a case-control study that compared associations between AAT with CRC risk and race of African-American (AA) and non-Hispanic white (NHW) men with incident CRC matched by age, body mass index, and race (N = 158, 79/group)...
March 21, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28323437/potato-consumption-and-risk-of-colorectal-cancer-in-the-norwegian-women-and-cancer-cohort
#2
Lene A Åsli, Anja Olsen, Tonje Braaten, Eiliv Lund, Guri Skeie
Potatoes are the fourth most plentiful food crop in the world, yet the scientific literature on the health effects of potato consumption is scarce. This study aimed to investigate the association between potato consumption and the risk of colorectal cancer (CRC) among 79,778 women aged 41-70, in the Norwegian Women and Cancer study. Information on diet, lifestyle, and health was collected by questionnaire. CRC cases (n  =  912) were identified through registry linkage. Adjusted Cox proportional hazard models were used to estimate the association between potato consumption and the risk of CRC...
March 21, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28320200/clinical-and-biological-features-of-interval-colorectal-cancer
#3
Yu Mi Lee, Kyu Chan Huh
Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs...
March 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28317592/long-term-prognostic-value-of-preoperative-anemia-in-patients-with-colorectal-cancer-a-systematic-review-and-meta-analysis
#4
REVIEW
M J Wilson, M van Haaren, J J Harlaar, Hee Chul Park, H J Bonjer, J Jeekel, J J Zwaginga, M Schipperus
OBJECTIVE: To evaluate the long-term prognostic factor of preoperative anemia in colorectal cancer patients. BACKGROUND: Anemia is frequently observed in colorectal cancer patients, with a case incidence of 30 to 67 percent. Besides an indicator of tumor-induced blood loss and inflammation, anemia in cancer is also suggested to be a cause of inferior outcome, possibly via worsening of tumor hypoxia. As surgery is likely to enhance anemia, the long-term prognostic value of preoperative anemia seems most interesting...
March 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28316155/-reevaluation-of-the-methodological-quality-in-meta-analyses-of-accelerated-rehabilitation-on-recovery-after-surgery-for-colorectal-cancer
#5
S N Ding, H Y Pan, J G Zhang
Objective: To evaluate the methodological quality and impacts on outcomes for systematic reviews (SRs) of accelerated rehabilitation versus traditional control for colorectal surgery. Methods: We comprehensively searched six databases and additional websites to collect SRs, or meta-analysis from inception to July 2016. The Overview Quality Assessment Questionnaire (OQAQ) was applied for quality assessment of the included studies, the tools recommended by the Cochrane Collaboration was applied for quality assessment for RCT and CCT and the Newcastle-Ottawa Scale (NOS) was applied to assess observational study...
March 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28315607/correcting-bias-due-to-missing-stage-data-in-the-non-parametric-estimation-of-stage-specific-net-survival-for-colorectal-cancer-using-multiple-imputation
#6
Milena Falcaro, James R Carpenter
BACKGROUND: Population-based net survival by tumour stage at diagnosis is a key measure in cancer surveillance. Unfortunately, data on tumour stage are often missing for a non-negligible proportion of patients and the mechanism giving rise to the missingness is usually anything but completely at random. In this setting, restricting analysis to the subset of complete records gives typically biased results. Multiple imputation is a promising practical approach to the issues raised by the missing data, but its use in conjunction with the Pohar-Perme method for estimating net survival has not been formally evaluated...
March 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28314318/systemic-inflammatory-response-after-preoperative-chemoradiotherapy-can-affect-oncologic-outcomes-in-locally-advanced-rectal-cancer
#7
In Hee Lee, Soyoon Hwang, Soo Jung Lee, Byung Woog Kang, Dongwon Baek, Hye Jin Kim, Su Yeon Park, Jun Seok Park, Gyu Seog Choi, Jae Chul Kim, Seung Hyun Cho, Jong Gwang Kim
AIM: Systemic inflammatory response (SIR) has been reported to be an important determinant of disease progression and survival in patients with colorectal cancer. This study investigated the prognostic relevance of changes in the platelet count on survival and the predictive value of changes in platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) on the pathological tumor response to preoperative chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (LARC)...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28314294/mismatch-repair-protein-deficiency-is-a-risk-factor-for-aberrant-expression-of-hla-class-i-molecules-a-putative-adaptive-immune-escape-phenomenon
#8
Terufumi Kubo, Yoshihiko Hirohashi, Kazuhiko Matsuo, Tomoko Sonoda, Hiroki Sakamoto, Kiyoshi Furumura, Tomohide Tsukahara, Takayuki Kanaseki, Munehide Nakatsugawa, Hiroshi Hirano, Tomohisa Furuhata, Ichiro Takemasa, Tadashi Hasegawa, Toshihiko Torigoe
Accumulating evidence indicates that immune checkpoint inhibition-mediated cancer immunotherapies greatly improve the prognosis of certain types of cancer. This approach is now becoming a standard therapy, joining surgery, radiotherapy, and chemotherapy. Because the costs of antibody drugs are now a socioeconomic burden in many countries, an urgent need in cancer immunotherapy is the identification of relevant biomarkers that can predict therapy efficacy. Recent studies have reported that colorectal adenocarcinoma with hereditary or sporadic deficiency in mismatch repair (MMR) proteins has high antigenicity and that detection of these proteins could be a promising way to estimate clinical response...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28298476/a-meta-analysis-between-dietary-carbohydrate-intake-and-colorectal-cancer-risk-evidence-from-17-observational-studies
#9
Jian Huang, Guoqing Pan, Hongchao Jiang, Wenliang Li, Jian Dong, Hongbin Zhang, Xiang Ji, Zhu Zhu
   The association between dietary carbohydrate intake and colorectal cancer risk remains controversial. We therefore conducted this meta-analysis to assess the relationship between them. A literature search from the databases of Pubmed, Embase, Web of science and Medline databases were performed for available articles published in English (up to Sep 2016). Pooled relative risk (RR) with 95% confidence interval (CI) was calculated to evaluate the association between dietary carbohydrate intake and colorectal cancer risk...
March 15, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28296927/harms-benefits-and-costs-of-fecal-immunochemical-testing-versus-guaiac-fecal-occult-blood-testing-for-colorectal-cancer-screening
#10
S Lucas Goede, Linda Rabeneck, Marjolein van Ballegooijen, Ann G Zauber, Lawrence F Paszat, Jeffrey S Hoch, Jean H E Yong, Sonja Kroep, Jill Tinmouth, Iris Lansdorp-Vogelaar
BACKGROUND: The ColonCancerCheck screening program for colorectal cancer (CRC) in Ontario, Canada, is considering switching from biennial guaiac fecal occult blood test (gFOBT) screening between age 50-74 years to the more sensitive, but also less specific fecal immunochemical test (FIT). The aim of this study is to estimate whether the additional benefits of FIT screening compared to gFOBT outweigh the additional costs and harms. METHODS: We used microsimulation modeling to estimate quality adjusted life years (QALYs) gained and costs of gFOBT and FIT, compared to no screening, in a cohort of screening participants...
2017: PloS One
https://www.readbyqxmd.com/read/28296776/totally-laparoscopic-associating-liver-tourniquet-and-portal-vein-occlusion-for-staged-hepatectomy-combined-with-simultaneous-left-hemicolectomy-for-bilateral-liver-metastases-of-the-primary-colon-cancer-a-case-report
#11
Hong-Wei Xu, Hong-Yu Li, Fei Liu, Yong-Gang Wei, Bo Li
BACKGROUND: Resection of the liver is often limited to the insufficient future liver remnant (FLR). To address this problem, the modification surgical technique "associating liver tourniquet and portal vein occlusion for staged hepatectomy" (ALTPS) was developed and led to quick hypertrophy in a short interval. In some colorectal cancer patients with multiple and bilobar metastases, the resection of the primary is often protracted immensely to the unpredictable postoperative complications for whom is to be treated with a liver-first approach...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28295697/diagnostic-capability-of-colon-capsule-endoscopy-for-advanced-colorectal-cancer-a-pilot-study
#12
Yumiko Ota, Atsuo Yamada, Yuka Kobayashi, Ryota Niikura, Takayuki Shimpoh, Akiko Narita, Shuntaro Yoshida, Nobumi Suzuki, Hirotsugu Watabe, Yoshihiro Hirata, Soichiro Ishihara, Eiji Sunami, Toshiaki Watanabe, Kazuhiko Koike
OBJECTIVES: Colon capsule endoscopy (CCE) is a safe and effective method for detecting lesions in the colon. However, the sensitivity of CCE in detecting advanced colorectal cancer (CRC) has not been sufficiently evaluated. Therefore, the aim of this study was to assess the sensitivity of CCE in detecting advanced CRC. METHODS: Patients previously diagnosed with advanced CRC by conventional colonoscopy underwent CCE. The primary outcome measure was the sensitivity of CCE in detecting advanced CRC per patient and per lesion...
March 10, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28295283/novel-colon-cancer-susceptibility-variants-identified-from-a-genome-wide-association-study-in-african-americans
#13
Hansong Wang, Stephanie L Schmit, Christopher A Haiman, Temitope O Keku, Ikuko Kato, Julie R Palmer, David van den Berg, Lynne R Wilkens, Terrilea Burnett, David V Conti, Fredrick R Schumacher, Lisa B Signorello, William J Blot, Krista A Zanetti, Curtis Harris, Mala Pande, Sonja I Berndt, Polly A Newcomb, Dee W West, Robert Haile, Daniel O Stram, Jane C Figueiredo, Loïc Le Marchand
Genome-wide association studies (GWAS) in ethnic/racial minority populations can help to fine-map previously identified risk regions or discover new risk loci because of the genetic diversity in these populations. We conducted a GWAS of colorectal cancer (CRC) in 6,597 African Americans (1,894 cases and 4,703 controls) (Stage 1) and followed up the most promising markers in a replication set of 2,041 participants of African descent (891 cases and 1,150 controls) (Stage 2). We identified a novel variant, rs56848936 in the gene SYMPK at 19q13...
March 13, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28288057/mesorectal-excision-with-or-without-lateral-lymph-node-dissection-for-clinical-stage-ii-iii-lower-rectal-cancer-jcog0212-a-multicenter-randomized-controlled-noninferiority-trial
#14
Shin Fujita, Junki Mizusawa, Yukihide Kanemitsu, Masaaki Ito, Yusuke Kinugasa, Koji Komori, Masayuki Ohue, Mitsuyoshi Ota, Yoshihiro Akazai, Manabu Shiozawa, Takashi Yamaguchi, Hiroyuki Bandou, Kenji Katsumata, Kohei Murata, Yoshihito Akagi, Nobuhiro Takiguchi, Yoshihisa Saida, Kenichi Nakamura, Haruhiko Fukuda, Takayuki Akasu, Yoshihiro Moriya
OBJECTIVE: The aim of the study was to confirm the noninferiority of mesorectal excision (ME) alone to ME with lateral lymph node dissection (LLND) in terms of efficacy. BACKGROUND: Lateral pelvic lymph node metastasis is occasionally found in clinical stage II or III lower rectal cancer, and ME with LLND is the standard procedure in Japan. ME alone, however, is the international standard surgical procedure for rectal cancer. METHODS: Eligibility criteria included histologically proven rectal cancer at clinical stage II/III; main lesion located in the rectum, with the lower margin below the peritoneal reflection; no lateral pelvic lymph node enlargement; Peformance Status of 0 or 1; and age 20 to 75 years...
March 10, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28288025/coffee-and-cancer-risk-a-summary-overview
#15
Gianfranco Alicandro, Alessandra Tavani, Carlo La Vecchia
We reviewed available evidence on coffee drinking and the risk of all cancers and selected cancers updated to May 2016. Coffee consumption is not associated with overall cancer risk. A meta-analysis reported a pooled relative risk (RR) for an increment of 1 cup of coffee/day of 1.00 [95% confidence interval (CI): 0.99-1.01] for all cancers. Coffee drinking is associated with a reduced risk of liver cancer. A meta-analysis of cohort studies found an RR for an increment of consumption of 1 cup/day of 0.85 (95% CI: 0...
March 10, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28284575/mfolfox6-plus-panitumumab-versus-5-fu-lv-plus-panitumumab-after-six-cycles-of-frontline-mfolfox6-plus-panitumumab-a-randomized-phase-ii-study-of-patients-with-unresectable-or-advanced-recurrent-ras-wild-type-colorectal-carcinoma-sapphire-study-design-and%C3%A2-rationale
#16
Naoki Nagata, Hideyuki Mishima, Shuichi Kurosawa, Koji Oba, Junichi Sakamoto
BACKGROUND: In Japan, oxaliplatin (OXA)/5-fluorouracil (5-FU)/leucovorin (LV)-the mFOLFOX6 regimen-is the most frequently used first-line chemotherapy backbone for metastatic colorectal cancer. However, peripheral nerve disorders caused by OXA during mFOLFOX6 therapy can decrease patients' quality of life. OXA can be safely discontinued from a FOLFOX regimen after 6 cycles during first-line therapy. Also, for patients who discontinue OXA without having experienced peripheral nerve disorders, reintroducing OXA in the later stages of treatment could remain an option...
March 1, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28282021/utilization-of-clinical-preventive-services-for-cancer-and-heart-disease-among-insured-adults-united-states-2015
#17
Anjel Vahratian, Stephen J Blumberg
Data from the National Health Interview Survey •Two-thirds of insured adults aged 50-75 were screened for colorectal cancer within the recommended intervals. •Insured women aged 30-39 (90.5%) were more likely than their older peers to be screened for cervical cancer within the recommended intervals. •Seventy-three percent of insured women aged 50-74 had a mammogram in the past 2 years. •The percentage of insured adults who had a cardiovascular risk screening (blood pressure, blood sugar) within the recommended intervals significantly increased with advancing age for both men and women...
March 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28281559/oral-bisphosphonates-and-colorectal-cancer
#18
Emily Vogtmann, Douglas A Corley, Lucy M Almers, Chris R Cardwell, Liam J Murray, Christian C Abnet
Use of oral bisphosphonates has been associated with a decreased risk of colorectal cancer (CRC), but the association may be related to residual confounding by healthy lifestyle or body mass index (BMI). Therefore, we conducted a prospective nested case-control study within the Kaiser Permanente, Northern California health system cohort. In total, 12,505 CRC cases were individually matched to 599,534 controls. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using conditional logistic regression models with adjustment for important covariates extracted from the database...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28281245/medicare-modernization-and-diffusion-of-endoscopy-in-ffs-medicare
#19
Lee R Mobley, Pedro Amaral, Tzy-Mey Kuo, Mei Zhou, Srimoyee Bose
OBJECTIVE: To examine how FFS Medicare utilization of endoscopy procedures for colorectal cancer (CRC) screening changed after implementation of the Medicare Prescription Drug, Improvement, and Modernization Act (MMA) in 2006, which provided subsidized drug coverage and expanded the geographic availability of Medicare managed care plans across the US. DATA SOURCES/STUDY SETTING: Using secondary data from 100% FFS Medicare enrollees, we analyzed endoscopy utilization during two intervals, 2001-2005 and 2006-2009...
December 2017: Health Economics Review
https://www.readbyqxmd.com/read/28280603/family-history-of-colorectal-cancer-and-its-impact-on-survival-in-patients-with-resected-stage-iii-colon-cancer-results-from-ncctg-trial-n0147-alliance
#20
Claire L Jansson-Knodell, Nathan R Foster, Daniel J Sargent, Paul J Limburg, Stephen N Thibodeau, Thomas C Smyrk, Frank A Sinicrope, Balkrishna Jahagirdar, Richard M Goldberg, Steven R Alberts
BACKGROUND: Family history of colon cancer often portends increased risk of disease development; however, the prognostic significance of family history related to disease and survival outcomes is unclear. METHODS: To investigate the relationship between family history of colorectal cancer and survival outcomes in stage III colon cancer patients, a prospective cohort of 1,935 patients with resected stage III colon cancer enrolled in a randomized controlled trial (N0147), comparing the standard of care FOLFOX to FOLFOX with cetuximab, was studied...
February 2017: Journal of Gastrointestinal Oncology
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