keyword
MENU ▼
Read by QxMD icon Read
search

Astaxanthin

keyword
https://www.readbyqxmd.com/read/29468878/identification-of-a-novel-esterase-from-marine-environmental-genomic-dna-libraries-and-its-application-in-production-of-free-all-trans-astaxanthin
#1
Ping Lu, Xinwei Gao, Hao Dong, Zhen Liu, Francesco Secundo, Changhu Xue, Xiangzhao Mao
Astaxanthin is a pigment with various functions. Free astaxanthin is obtained mainly through saponification methods, which could result in many by-products. Enzymatic methods using lipases have been used in few cases, while there are no reports on the use of esterases for the production of free astaxanthin. Herein we present the screening and identification of a novel esterase (Est3-14) from a marine mud metagenomic library. Est3-14 is pH-sensitive and keeps good stability in akaline buffers (residual activity 94%, pH 8...
February 22, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29413919/investigations-in-ultrasound-induced-enhancement-of-astaxanthin-production-by-wild-strain-phaffia-rhodozyma-mtcc-7536
#2
Amit H Batghare, Neha Singh, Vijayanand S Moholkar
This work reports ultrasound-induced enhancement of astaxanthin production in batch fermentation using wild strain of P. rhodozyma MTCC 7536. The methodology adopted in this study comprises of statistical optimization of the medium and fermentation parameters, followed by application of sonication at optimized conditions. P. rhodozyma fermentation at conditions of 20 g/L glucose, pH 4.4, temperature 21 °C, 4% v/v inoculum, shaking at 205 rpm with nitrogen sources of (NH4)2SO4 and yeast extract yielded 6...
January 26, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29412454/antioxidant-properties-of-astaxanthin-in-oil-in-water-emulsions-with-differently-charged-emulsifiers-under-chlorophyll-photosensitization
#3
BoRa Yi, Mi-Ja Kim, JaeHwan Lee
The antioxidative or prooxidative properties of astaxanthin at the concentrations of 0, 10, and 100 μM were determined in oil-in-water (O/W) emulsions containing neutral, anionic, and cationic emulsifiers, which was Tween 20, sodium dodecyl sulfate, cetyltrimethylammonium bromide (CTAB), respectively, under chlorophyll photosensitization. The oxidative parameters and headspace volatiles were analyzed in O/W emulsions. In the 24 h period of visible light irradiation, 100 μM of astaxanthin acted as an antioxidant in O/W emulsions containing neutral and anionic emulsifiers...
February 7, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29384321/astaxanthin-improves-glucose-metabolism-and-reduces-blood-pressure-in-patients-with-type-2-diabetes-mellitus
#4
Nafiseh Sokri Mashhadi, Mehrnoosh Zakerkish, Javad Mohammadiasl, Mehdi Zarei, Majid Mohammadshahi, Mohammad Hossein Haghighizadeh
BACKGROUND AND OBJECTIVES: This randomized, placebo-controlled trial was performed for 8 weeks to investigate the potential effects of astaxanthin (AST) supplementation on the adiponectin concentration, lipid peroxidation, glycemic control, insulin sensitivity, and anthropometric indices in participants with type 2 diabetes mellitus. METHODS AND STUDY DESIGN: We enrolled 44 participants with type 2 diabetes who met our inclusion criteria. Eight milligrams of AST supplementation or a placebo were randomly administered once daily for 8 weeks to these participants...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29381356/astaxanthin-induces-the-nrf2-ho-1-antioxidant-pathway-in-human-umbilical-vein-endothelial-cells-by-generating-trace-amounts-of-ros
#5
Tingting Niu, Rongrong Xuan, Ligang Jiang, Wei Wu, Zhanghe Zhen, Yuling Song, Lili Hong, Kaiqin Zheng, Jiaxing Zhang, Qingshan Xu, Yinghong Tan, Xiaojun Yan, Haimin Chen
Astaxanthin is a powerful antioxidant that possesses potent protective effects against various human diseases and physiological disorders. However, the mechanisms underlying its antioxidant functions in cells are not fully understood. In the present study, the effects of astaxanthin on reactive oxygen species (ROS) production and antioxidant enzyme activity, as well as mitogen-activated protein kinases (MAPKs), phosphatidylinositol 3-kinase (PI3K)/Akt, and the nuclear factor erythroid 2-related factor 2 (Nrf-2)/heme oxygenase-1 (HO-1) pathways in human umbilical vein endothelial cells (HUVECs) were examined...
January 30, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29378496/nutraceuticals-to-promote-neuronal-plasticity-in-response-to-corticosterone-induced-stress-in-human-neuroblastoma-cells
#6
Snehal Gite, R Paul Ross, Dara Kirke, Freddy Guihéneuf, Justine Aussant, Dagmar B Stengel, Timothy G Dinan, John F Cryan, Catherine Stanton
OBJECTIVES: To search for novel compounds that will protect neuronal cells under stressed conditions that may help to restore neuronal plasticity. METHODS: A model of corticosterone (CORT)-induced stress in human neuroblastoma cells (SH-SY5Y) was used to compare the efficacy of 6 crude extracts and 10 pure compounds (6 polyphenols, 2 carotenoids, 1 amino acid analogue, and 1 known antidepressant drug) to increase neuronal plasticity and to decrease cytotoxicity...
January 29, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29371561/biosynthesis-of-astaxanthin-as-a-main-carotenoid-in-the-heterobasidiomycetous-yeast-xanthophyllomyces-dendrorhous
#7
REVIEW
Jose L Barredo, Carlos García-Estrada, Katarina Kosalkova, Carlos Barreiro
Carotenoids are organic lipophilic yellow to orange and reddish pigments of terpenoid nature that are usually composed of eight isoprene units. This group of secondary metabolites includes carotenes and xanthophylls, which can be naturally obtained from photosynthetic organisms, some fungi, and bacteria. One of the microorganisms able to synthesise carotenoids is the heterobasidiomycetous yeast Xanthophyllomyces dendrorhous, which represents the teleomorphic state of Phaffia rhodozyma, and is mainly used for the production of the xanthophyll astaxanthin...
July 30, 2017: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29368247/astaxanthin-attenuates-contrast-agent-induced-acute-kidney-injury-in-vitro-and-in-vivo-via-the-regulation-of-sirt1-foxo3a-expression
#8
Nana Liu, Jing Chen, Dongmei Gao, Wenhua Li, Di Zheng
PURPOSE: The study was processed to investigate the effect of astaxanthin (AST; 3,3-dihydroxybeta, beta-carotene-4,4-dione) on the acute kidney injury induced by iohexol and the relationship with SIRT1/FOXO3a signal pathway. METHODS: Thirty male Sprague Dawley rats were randomly divided into five groups as follows: control group (CON; olive oil only), contrast media group, astaxanthin control group (100 mg/kg), low astaxanthin dose group (LAG, 50 mg/kg) and high astaxanthin dose group (HAG, 100 mg/kg)...
January 24, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29362867/the-stem-cell-factor-stimulated-melanogenesis-in-human-melanocytes-can-be-abrogated-by-interrupting-the-phosphorylation-of-msk1-evidence-for-involvement-of-the-p38-msk1-creb-mitf-axis
#9
Takao Niwano, Shuko Terazawa, Hiroaki Nakajima, Genji Imokawa
We recently found that treatment of normal human melanocytes (NHMs) with the antioxidant astaxanthin (AX) suppresses the stem cell factor (SCF)-stimulated protein expression levels of microphthalmia-associated transcription factor (MITF) at 1.5 h and of tyrosinase and endothelin B receptor at 96 h post-treatment. Analysis of the signaling cascade(s) involved revealed that although the major SCF-activated signaling cascade that leads to CREB activation (the c-KIT/Shc/Raf-1/ERK/RSK/CREB axis) is not interrupted, the increased phosphorylation of CREB is significantly abrogated by AX...
January 23, 2018: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29346532/what-color-should-glacier-algae-be
#10
Roman J Dial, Gerard Q Ganey, S McKenzie Skiles
Red-colored secondary pigments in glacier algae play an adaptive role in melting snow and ice. We advance this hypothesis using a model of color-based absorption of irradiance, an experiment with colored particles in snow, and the natural history of glacier algae. Carotenoids and phenols-astaxanthin in snow-algae and purpurogallin in ice-algae-shield photosynthetic apparatus by absorbing over-abundant visible wavelengths, then dissipating the excess radiant energy as heat. This heat melts proximal ice crystals, providing liquid-water in a 0°C environment and freeing-up nutrients bound in frozen water...
January 15, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29345928/physicochemical-properties-of-whey-protein-stabilized-astaxanthin-nanodispersion-and-its-transport-via-caco-2-monolayer
#11
Xue Shen, Changhui Zhao, Jing Lu, Mingruo Guo
Astaxanthin nanodispersion was prepared using whey protein isolate (WPI) and polymerized whey protein (PWP) through an emulsification-evaporation technique. The physicochemical properties of the astaxanthin nanodispersion were evaluated and the transport of astaxanthin was assessed using a Caco-2 cell monolayer model. The astaxanthin nanodispersions stabilized by WPI and PWP (2.5%, w/w) had a small particle size (121 ± 4.9 and 80.4 ± 5.9 nm), negative zeta potential (-19.3 ± 1.5 and -35.0 ± 2.2 mV), and high encapsulation efficiency (92...
January 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29333626/effect-of-astaxanthin-on-the-quality-of-boar-sperm-stored-at-17%C3%A2-c-incubated-at-37%C3%A2-c-or-under-in-vitro-conditions
#12
A Basioura, C M Boscos, I Parrilla, G Tsousis, I A Tsakmakidis
The aim of the study was to investigate the effect of the antioxidant astaxanthin on boar semen. Twenty ejaculates from 10 boars (two ejaculates/boar) were extended and split in three groups: semen control (SC), solvent control (C; semen with dimethyl sulfoxide, the diluent of astaxanthin) and semen with astaxanthin (A) in concentration 0.5 μmol/L. Sperm quality parameters (motility and kinetics, morphology, viability, functional integrity of sperm plasma membrane by Hypo-Osmotic Swelling Test [HOST] and DNA integrity) were assessed at 0, 24 and 48 hr of storage at 17°C (experiment I), before (0 hr) and after (1 hr) of sperm thermal resistance assay at 37°C (experiment II) and finally before (0 hr) and after (1 hr) sperm in vitro incubation (38...
January 14, 2018: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/29333048/astaxanthin-ameliorates-hepatic-damage-and-oxidative-stress-in-carbon-tetrachloride-administered-rats
#13
Md Ariful Islam, Md Abdullah Al Mamun, Md Faruk, Md Tauhid Ul Islam, Md Mizanur Rahman, Mohammad Nazmul Alam, A F M Towheedur Rahman, Hasan Mahmud Reza, Md Ashraful Alam
Background: Astaxanthin is of carotenoids group which possess strong antioxidant properties. The present study was conducted to evaluate the hepatoprotective effects of astaxanthin in carbon tetrachloride (CCl4)-treated rats. Materials and Methods: Female Long-Evans rats were administered with CCl4 orally (1 ml/kg) twice a week for 2 weeks and were treated with astaxanthin (10 mg/kg) every day for 2 weeks. Blood plasma samples were isolated from each group and were analyzed for alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase activities...
December 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/29329855/production-of-three-types-of-krill-oils-from-krill-meal-by-a-three-step-solvent-extraction-procedure
#14
Dan Xie, Hongyan Mu, Tianpei Tang, Xiaosan Wang, Wei Wei, Jun Jin, Xingguo Wang, Qingzhe Jin
In this study, a three-step extraction method (separately use acetone, hexane, and ethanol as extraction solvent in each step) was conducted to selectively extract three types of krill oils with different compositions. The lipid yields were 5.08% in step 1, 4.80% in step 2, and 9.11% in step 3, with a total of 18.99%. The krill oil extracted with acetone in step 1 (A-KO) contained the lowest contents of phospholipids (PL) (2.32%) and n-3 polyunsaturated fatty acids (PUFA) (16.63%), but the highest levels of minor components (505...
May 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29328945/astaxanthin-ameliorates-cerulein-induced-acute-pancreatitis-in-mice
#15
Hui Zhang, Wenjuan Yang, Yueyue Li, Liangkai Hu, Ying Dai, Jianqing Chen, Shuqi Xu, Xuanfu Xu, Haiqiong Jiang
BACKGROUND: A various of pharmacological effects of astaxanthin has been confirmed. However, the mechanism underlying protective effect of astaxanthin on acute pancreatitis (AP) induced by cerulein still unclear. The present study is to investigate the mechanism underlying the effect of astaxanthin on autophagy and apoptosis via the JAK/STAT3 pathway. METHODS: Intraperitoneal injection of cerulein at hourly intervals followed by lipopolysaccharide injection were used in Balb/C mice...
January 9, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29319312/induced-high-yield-production-of-zeaxanthin-lutein-and-%C3%AE-carotene-by-a-mutant-of-chlorella-zofingiensis
#16
Weiping Huang, Yan Lin, Mingxia He, Yuhao Gong, Junchao Huang
Natural resources of zeaxanthin are extremely limited. A Chlorella zofingiensis mutant (CZ-bkt1), which could accumulate high amounts of zeaxanthin, was generated and characterized. CZ-bkt1 was achieved by treating the algal cells with a chemical mutagen followed by a colour-based colony screening approach. CZ-bkt1 was found to consist of a dysfunctional carotenoid ketolase, leading to the accumulation of zeaxanthin rather than its downstream ketocarotenoid astaxanthin. Light irradiation, glucose, NaCl, and nitrogen deficiency all induced CZ-bkt1 to accumulate zeaxanthin...
January 10, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29316673/transcriptome-analysis-in-haematococcus-pluvialis-astaxanthin-induction-by-high-light-with-acetate-and-fe2
#17
Bangxiang He, Lulu Hou, Manman Dong, Jiawei Shi, Xiaoyun Huang, Yating Ding, Xiaomei Cong, Feng Zhang, Xuecheng Zhang, Xiaonan Zang
Haematococcus pluvialis is a commercial microalga, that produces abundant levels of astaxanthin under stress conditions. Acetate and Fe2+ are reported to be important for astaxanthin accumulation in H. pluvialis. In order to study the synergistic effects of high light stress and these two factors, we obtained transcriptomes for four groups: high light irradiation (HL), addition of 25 mM acetate under high light (HA), addition of 20 μM Fe2+ under high light (HF) and normal green growing cells (HG). Among the total clean reads of the four groups, 156,992 unigenes were found, of which 48...
January 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29287452/changes-in-the-gaba-and-polyphenols-contents-of-foxtail-millet-on-germination-and-their-relationship-with-in-vitro-antioxidant-activity
#18
Seema Sharma, Dharmesh C Saxena, Charanjit S Riar
Germination along with ultrasonic assisted extraction induced a significant beneficial effect on the characteristics of polyphenolic components profile, GABA contents and in vitro antioxidant capacity of the foxtail millet flour extracts. The total antioxidant activity (29.0-45.23 mgAAE/g) and reducing power (0.53-0.76 µg/ml) increase during germination were due to quantitative increase in phthalicacid; hex-3yl-ester; hexadecanoicacid methylester etc. whereas, increase in DPPH (48.32-59.62%) and hydrogen peroxide scavenging activities (35...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29286507/study-the-impact-of-astaxanthin-on-developing-of-genomic-instability-in-human-peripheral-blood-lymphocytes-irradiated-in-vitro-on-g2-phase-of-cell-cycle
#19
D A Кurinnyi, S R Rushkovsky, O M Demchenko, M A Pilinska
OBJECTIVE: To identify the possibility of modification by astaxanthin the level of genome damages induced by gamma quanta in the culture of human peripheral blood lymphocytes exposed in vitro on postsynthetic (G2) phase of the first mitotic cycle. MATERIALS AND METHODS: Peripheral blood lymphocytes from four apparently healthy volunteers 35-51 years old were cultivated using modified micromethod. To obtain genomic damages in G2 phase of the first mitotic cycle the part of cultures was irradiated by γ quanta in dose 1...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29278377/media-screening-for-obtaining-haematococcus-pluvialis-red-motile-macrozooids-rich-in-astaxanthin-and-fatty-acids
#20
Thomas O Butler, Gordon J McDougall, Raymond Campbell, Michele S Stanley, John G Day
Astaxanthin from Haematococcus pluvialis is commercially produced in a two-stage process, involving green vegetative (macrozooid) and red aplanospore stages. This approach has been scaled up to an industrial process but constraints limit its commercial success and profitability, including: contamination issues, high pigment extraction costs, requirements for high light levels and photo-bleaching in the red stage. However, in addition to the aplanospore stage, this alga can produce astaxanthin in vegetative palmelloid and motile macrozooid cells...
December 26, 2017: Biology
keyword
keyword
11320
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"