keyword
MENU ▼
Read by QxMD icon Read
search

Astaxanthin

keyword
https://www.readbyqxmd.com/read/28781026/comparison-of-low-dose-statin-versus-low-dose-statin%C3%A2-%C3%A2-armolipid-plus-in-high-intensity-statin-intolerant-patients-with-a-previous-coronary-event-and-percutaneous-coronary-intervention-adherence-trial
#1
Giuseppe Marazzi, Giuseppe Campolongo, Francesco Pelliccia, Silvia Quattrino, Cristiana Vitale, Luca Cacciotti, Rosalba Massaro, Maurizio Volterrani, Giuseppe Rosano
Low-density lipoprotein cholesterol (LDL-C) reduction is associated with a significant decrease in mortality, and statins represent the most effective drugs to achieve this. However, side effects of statins are very common and may lead to treatment discontinuation. Nutraceuticals are a combination of natural components that have shown efficacy in lowering LDL-C concentration when used alone or in association with other agents in patients who are intolerant to high-dose statins. Our aim was to compare the efficacy and tolerability of low-dose statin (LDS) therapy versus combined therapy of LDS plus a nutraceutical combination containing red yeast rice, policosanol, berberine, folic acid, coenzyme Q10 and astaxanthin (Armolipid Plus) in high-risk patients...
June 28, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28770048/environmental-stress-linked-to-consumption-of-maternally-derived-carotenoids-in-brown-trout-embryos-salmo-trutta
#2
Laetitia G E Wilkins, Lucas Marques da Cunha, Gaëtan Glauser, Armelle Vallat, Claus Wedekind
The yellow, orange, or red colors of salmonid eggs are due to maternally derived carotenoids whose functions are not sufficiently understood yet. Here, we studied the significance of naturally acquired carotenoids as maternal environmental effects during embryo development in brown trout (Salmo trutta). We collected eggs from wild females, quantified their egg carotenoid content, fertilized them in vitro in full-factorial breeding blocks to separate maternal from paternal effects, and raised 3,278 embryos singly at various stress conditions until hatching...
July 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28765773/astaxanthin-induces-migration-in-human-skin-keratinocytes-via-rac1-activation-and-rhoa-inhibition
#3
Dakanda Ritto, Supita Tanasawet, Sawana Singkhorn, Wanwimol Klaypradit, Pilaiwanwadee Hutamekalin, Varomyalin Tipmanee, Wanida Sukketsiri
BACKGROUND/OBJECTIVES: Re-epithelialization has an important role in skin wound healing. Astaxanthin (ASX), a carotenoid found in crustaceans including shrimp, crab, and salmon, has been widely used for skin protection. Therefore, we investigated the effects of ASX on proliferation and migration of human skin keratinocyte cells and explored the mechanism associated with that migration. MATERIAL/METHOD: HaCaT keratinocyte cells were exposed to 0.25-1 µg/mL of ASX...
August 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28763972/next-generation-nutraceutical-from-shrimp-waste-the-convergence-of-applications-with-extraction-methods
#4
REVIEW
Kandra Prameela, Kuncham Venkatesh, Sarat Babu Immandi, Ashok Phani Kiran Kasturi, Ch Rama Krishna, Ch Murali Mohan
In recent years considerable progress in health therapy makes a significant improvement in natural nutraceuticals. Shrimp is a valuable natural sea food and is processed by removing head, tail and carapace as waste. The large amounts of waste produced by sea food industries capitulate, recoverable nutraceutical compound astaxanthin. This review emphasizes the chemistry and role of astaxanthin in pigmentation. The study highlights progress in applications and describes the current extraction methods starting with chemical to the best eco-friendly microbial processes...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28761364/effect-of-astaxanthin-on-cutaneous-wound-healing
#5
Jitlada Meephansan, Atiya Rungjang, Werayut Yingmema, Raksawan Deenonpoe, Saranyoo Ponnikorn
Wound healing consists of a complex series of convoluted processes which involve renewal of the skin after injury. ROS are involved in all phases of wound healing. A balance between oxidative and antioxidative forces is necessary for a favorable healing outcome. Astaxanthin, a member of the xanthophyll group, is considered a powerful antioxidant. In this study, we investigated the effect of topical astaxanthin on cutaneous wound healing. Full-thickness dermal wounds were created in 36 healthy female mice, which were divided into a control group and a group receiving 78...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28753934/rapid-estimation-of-astaxanthin-and-the-carotenoid-to-chlorophyll-ratio-in-the-green-microalga-chromochloris-zofingiensis-using-flow-cytometry
#6
Junhui Chen, Dong Wei, Georg Pohnert
The green microalga Chromochloris zofingiensis can accumulate significant amounts of valuable carotenoids, mainly natural astaxanthin, a product with applications in functional food, cosmetics, nutraceuticals, and with potential therapeutic value in cardiovascular and neurological diseases. To optimize the production of astaxanthin, it is essential to monitor the content of astaxanthin in algal cells during cultivation. The widely used HPLC (high-performance liquid chromatography) method for quantitative astaxanthin determination is time-consuming and laborious...
July 19, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28751807/protective-effects-of-astaxanthin-on-skin-deterioration
#7
Kumi Tominaga, Nobuko Hongo, Mayuko Fujishita, Yu Takahashi, Yuki Adachi
Astaxanthin is a carotenoid with potent antioxidant and anti-inflammatory activity. To evaluate the anti-inflammatory effect of astaxanthin on skin deterioration, we confirmed its role in epidermal-dermal interactions in vitro. Astaxanthin treatment suppressed ultraviolet B (UVB)-induced inflammatory cytokine secretion in keratinocytes, and matrix metalloproteinase-1 secretion by fibroblasts cultured in UVB-irradiated keratinocyte medium. To verify these findings, we conducted a 16-week clinical study with 65 healthy female participants...
July 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/28751805/astaxanthin-ameliorates-ferric-nitrilotriacetate-induced-renal-oxidative-injury-in-rats
#8
Yasumasa Okazaki, Shigeru Okada, Shinya Toyokuni
Daily intake of vegetables can reduce the risk of cancer and lifestyle-related diseases. However, supplementary intake of β-carotene alone has been reported to increase the risk of lung cancer in male cigarette smokers and people who were exposed to asbestos. The mechanism of the antioxidative properties of carotenoids in vivo, especially under oxidative stress conditions, still remains unclear. To investigate the antioxidant properties of dietary compounds, we examined the effects of chemically modified astaxanthin (Ax-C-8) using a rat model of ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative injury...
July 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/28738843/astaxanthin-mitigates-cobalt-cytotoxicity-in-the-mg-63-cells-by-modulating-the-oxidative-stress
#9
Dahe Li, Wenwen Tong, Denghui Liu, Yuming Zou, Chen Zhang, Weidong Xu
BACKGROUND: With the re-popularity of metal-on-metal (MoM) bearing in recent years, the cobalt toxicity has been a cause for concern in the total hip replacement surgery by both physicians and patients. METHODS: MG-63 cell line was cultured in vitro and incubated with cobalt (II) chloride (CoCl2) and/or with astaxanthin (ASX) for 24 h. MTT assay was conducted to evaluate the cell viability after cobalt exposure and ASX treatment. Fluorescence-activated cell sorting (FACS) analysis was performed to examine the reactive oxygen species (ROS) level...
July 24, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28738208/plastid-transformation-and-its-application-in-metabolic-engineering
#10
REVIEW
Paulina Fuentes, Tegan Armarego-Marriott, Ralph Bock
Metabolic pathway engineering by transgene expression from the plastid (chloroplast) genome offers significant attractions, including straightforward multigene engineering by pathway expression from operons, high transgene expression levels, and increased transgene containment due to maternal inheritance of plastids in most crops. In addition, it provides direct access to the large and diverse metabolite pools in chloroplasts and non-green plastid types. Here, we review recent progress with extending the toolbox for plastid engineering and highlight selected applications in the area of metabolic engineering, including the combined engineering of nuclear and plastid genomes for the production of artemisinic acid, the direct harness of chloroplast reducing power for the synthesis of dhurrin and the use of an edible host for the production of astaxanthin...
July 21, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28737395/kinetic-study-of-the-aroxyl-radical-scavenging-activity-of-five-fatty-acid-esters-and-six-carotenoids-in-toluene-solution-structure-activity-relationship-for-the-hydrogen-abstraction-reaction
#11
Kazuo Mukai, Maya Yoshimoto, Masaharu Ishikura, Shin-Ichi Nagaoka
A kinetic study of the reaction between an aroxyl radical (ArO(•)) and fatty acid esters (LHs 1-5, ethyl stearate 1, ethyl oleate 2, ethyl linoleate 3, ethyl linolenate 4, and ethyl arachidonate 5) has been undertaken. The second-order rate constants (ks) for the reaction of ArO(•) with LHs 1-5 in toluene at 25.0 °C have been determined spectrophotometrically. The ks values obtained increased in the order of LH 1 < 2 < 3 < 4 < 5, that is, with increasing the number of double bonds included in LHs 1-5...
August 8, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28724407/characterization-of-the-cytochrome-p450-monooxygenase-genes-p450ome-from-the-carotenogenic-yeast-xanthophyllomyces-dendrorhous
#12
Pamela Córdova, Ana-María Gonzalez, David R Nelson, María-Soledad Gutiérrez, Marcelo Baeza, Víctor Cifuentes, Jennifer Alcaíno
BACKGROUND: The cytochromes P450 (P450s) are a large superfamily of heme-containing monooxygenases involved in the oxidative metabolism of an enormous diversity of substrates. These enzymes require electrons for their activity, and the electrons are supplied by NAD(P)H through a P450 electron donor system, which is generally a cytochrome P450 reductase (CPR). The yeast Xanthophyllomyces dendrorhous has evolved an exclusive P450-CPR system that specializes in the synthesis of astaxanthin, a carotenoid with commercial potential...
July 19, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28720940/recovery-of-protein-hydrolysate-and-chitosan-from-black-tiger-shrimp-penaeus-monodon-heads-approaching-a-zero-waste-process
#13
Pham Thi Dan Phuong, Nguyen Cong Minh, Hoang Ngoc Cuong, Nguyen Van Minh, Nguyen The Han, Nguyen Van Hoa, Ha Thi Hai Yen, Trang Si Trung
Shrimp heads are considered as a potential source for the recovery of many valuable components such as chitin, protein and carotenoids. In the present study, both protein hydrolysate and chitin/chitosan were recovered using combination of physical, biological and chemical treatments. Shrimp heads were separated from liquid phase by a facile and efficient physical pretreatment. The liquid fraction was then hydrolyzed using formic acid and vacuum concentrated to obtain an astaxanthin-rich protein hydrolysate...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28698858/astaxanthin-and-%C3%AE-carotene-in-helicobacter-pylori-induced-gastric-inflammation-a-mini-review-on-action-mechanisms
#14
REVIEW
Hyunju Kang, Hyeyoung Kim
Helicobacter pylori is a dominant bacterium living in the human gastric tissues. In H. pylori-infected tissues, the infiltrated inflammatory cells produce reactive oxygen species (ROS), leading to gastric inflammation with production of various mediators. According to numerous epidemiological studies, dietary carotenoids may prevent gastric inflammation due to their antioxidant properties. Recent studies showed that antioxidant and anti-inflammatory effects of astaxanthin and β-carotene may contribute to inhibition of H...
June 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28694655/antioxidant-dietary-approach-in-treatment-of-fatty-liver-new-insights-and-updates
#15
REVIEW
Alessandra Ferramosca, Mariangela Di Giacomo, Vincenzo Zara
Non-alcoholic fatty liver disease (NAFLD) is a common clinicopathological condition, encompassing a range of conditions caused by lipid deposition within liver cells. To date, no approved drugs are available for the treatment of NAFLD, despite the fact that it represents a serious and growing clinical problem in the Western world. Identification of the molecular mechanisms leading to NAFLD-related fat accumulation, mitochondrial dysfunction and oxidative balance impairment facilitates the development of specific interventions aimed at preventing the progression of hepatic steatosis...
June 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28692413/effects-of-astaxanthin-on-liver-and-leukocyte-parameters-in-healthy-climacteric-women-preliminary-data
#16
Jui-Tung Chen, Kazuhiko Kotani
No abstract text is available yet for this article.
July 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28689962/astaxanthin-analogs-adonixanthin-and-lycopene-activate-nrf2-to-prevent-light-induced-photoreceptor-degeneration
#17
Yuki Inoue, Masamitsu Shimazawa, Ryota Nagano, Yoshiki Kuse, Kei Takahashi, Kazuhiro Tsuruma, Masahiro Hayashi, Takashi Ishibashi, Takashi Maoka, Hideaki Hara
Carotenoids, in particular astaxanthin, possess potent antioxidant capabilities. Astaxanthin also induces NF-E2-related factor 2 (Nrf2), which plays a major regulatory role in the antioxidative response. However, little is known whether the carotenoid, by-products of astaxanthin, activate Nrf2. Toward this end, we screened eight astaxanthin analogs for Nrf2 activation in murine photoreceptor cell line, 661 W, by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). In addition, we monitored cell death in 661 W cells pretreated with astaxanthin analogs or only pretreated for 6 h with astaxanthin analogs and then exposed to light...
June 21, 2017: Journal of Pharmacological Sciences
https://www.readbyqxmd.com/read/28665548/effect-of-astaxanthin-and-aluminum-chloride-on-erythrocyte-g6pd-and-6pgd-enzyme-activities-in-vivo-and-on-erythrocyte-g6pd-in-vitro-in-rats
#18
Yusuf Temel, Aydın Şükrü Bengü, Hurrem Turan Akkoyun, Mahire Akkoyun, Mehmet Ciftci
In this study, we investigated the effect of astaxanthin (Ast) and aluminum (Al) on the erythrocyte glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD) enzymes activities in vivo and on G6PD enzyme in vitro in rats. For in vitro studies, G6PD enzyme was purified from rat erythrocyte by using 2',5'-ADP-Sepharose 4B affinity gel. The effects of Ast and Al(3+) ion were investigated on the purified enzyme. It was determined that Ast increased the enzyme activity, whereas Al(3+) inhibited the enzyme activity noncompetitively (IC50 values; 0...
June 30, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28647321/development-of-large-scale-and-economic-ph-control-system-for-outdoor-cultivation-of-microalgae-haematococcus-pluvialis-using-industrial-flue-gas
#19
Yoon Young Choi, Jae Min Joun, Jeewon Lee, Min Eui Hong, Hoang-Minh Pham, Won Seok Chang, Sang Jun Sim
The aim of this study was to develop the economic and effective buffer system for microalgae mass cultivation using industrial flue gas. Due to the continuous flue gas supplement, culture media acidified, therefore cell growth inhibited. Although buffering agent was added, this result increase in cost for overall culture process. Therefore combined buffer system of bicarbonate and phosphate (BP) for large-scale use was investigated. The bicarbonate buffer system generated from CO2 dissolution, additionally phosphate buffer system improves the buffer performance under the continuous CO2 supplementation from flue gas...
May 26, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28636682/excited-state-characterization-of-carbonyl-containing-carotenoids-a-comparison-between-single-and-multireference-descriptions
#20
Riccardo Spezia, Stefan Knecht, Benedetta Mennucci
Carotenoids can play multiple roles in biological photoreceptors thanks to their rich photophysics. In the present work, we have investigated six of the most common carbonyl containing carotenoids: echinenone, canthaxanthin, astaxanthin, fucoxanthin, capsanthin and capsorubin. Their excitation properties are investigated by means of a hybrid density functional theory (DFT) and multireference configuration interaction (MRCI) approach to elucidate the role of the carbonyl group: the bright transition is of ππ* character, as expected, but the presence of a C[double bond, length as m-dash]O moiety reduces the energy of nπ* transitions which may become closer to the ππ* transition, in particular as the conjugation chain decreases...
June 21, 2017: Physical Chemistry Chemical Physics: PCCP
keyword
keyword
11320
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"