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https://www.readbyqxmd.com/read/27897305/-cervical-ischaemic-neuronopathy-and-cardioembolism-another-cause-of-man-in-the-barrel-syndrome
#1
H Gonzalez-Usigli, A Gandarilla, J J Garcia, J Serrato, N Estrada
INTRODUCTION: Spinal infarction accounts for 1% of all strokes. Cardioembolism is a rare cause. Common areas of ischemic spinal damage are watershed in the dorsal or lumbar regions; however cervical spinal cord infarction has been reported previously. CASE REPORT: We present a new case of a man-in-the-barrel syndrome produced by cardiac embolization associated with atrial fibrillation during an acute myocardial infarction, which caused cervical ischemic neuronopathy (infarction of the anterior horn)...
December 16, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27879570/bone-turnover-markers-as-a-new-predicting-factor-for-non-union-after-spinal-fusion-surgery
#2
Hiroyuki Inose, Tsuyoshi Yamada, Mieradili Mulati, Takashi Hirai, Shuta Ushio, Toshitaka Yoshii, Tsuyoshi Kato, Shigenori Kawabata, Atsushi Okawa
STUDY DESIGN: Retrospective observational study. OBJECTIVE: We investigated whether bone turnover markers could be a useful indicator for prediction of nonunion. SUMMARY OF BACKGROUND DATA: Nonunion is a major complication of lumbar spinal fusion surgery. However, the involvement of bone turnover in the process of bony union in spinal fusion surgery is poorly understood. METHODS: Of the 74 patients analyzed, 13 were diagnosed with nonunion...
November 22, 2016: Spine
https://www.readbyqxmd.com/read/27875927/what-is-being-trained-how-divergent-forms-of-plasticity-compete-to-shape-locomotor-recovery-after-spinal-cord-injury
#3
J Russell Huie, Kazuhito Morioka, Jenny Haefeli, Adam R Ferguson
Spinal cord injury (SCI) is a devastating syndrome that produces dysfunction in motor and sensory systems, manifesting as chronic paralysis, sensory changes, and pain disorders. The multifaceted and heterogeneous nature of SCI has made effective rehabilitative strategies challenging. Work over the last 40 years has aimed to overcome these obstacles by harnessing the intrinsic plasticity of the spinal cord to improve functional locomotor recovery. Intensive training after SCI facilitates lower extremity function and has shown promise as a tool for retraining the spinal cord by engaging innate locomotor circuitry in the lumbar cord...
November 22, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27862237/locally-applied-simvastatin-promotes-bone-formation-in-a-rat-model-of-spinal-fusion
#4
Toshinobu Ishihara, Masashi Miyazaki, Naoki Notani, Shozo Kanezaki, Masanori Kawano, Hiroshi Tsumura
Simvastatin, an inexpensive lipid-lowering drug widely used to prevent cardiovascular disorders, is known to increase osteoblastic activity, inhibit osteoclastic activity, and stimulate osteoblastic production of bone morphogenetic protein 2. Furthermore, local simvastatin application increased bone formation in animal models of fracture or bone defects. We investigated the effect of locally applied simvastatin in a rat model of spinal fusion. We performed posterolateral lumbar fusion surgery with iliac crest autograft in 36 rats divided into group I (n = 17; implanted with a gelatin scaffold) and group II (n = 19; implanted with a gelatin scaffold infused with 0...
November 11, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27858672/guide-wire-breakage-during-posterolateral-endoscopic-lumbar-discectomy-procedure-a-case-report
#5
Xiaofei Guan, Shan Zhao, Xin Gu, Hailong Zhang, Shisheng He
OBJECTIVE: To present a unique case of guide wire breakage as a rare complication during posterolateral endoscopic lumbar discectomy. BACKGROUND: Posterolateral endoscopic lumbar discectomy (PELD) has become a routinely performed minimally invasive spinal procedure. However, several complications of PELD have attracted our concerns, including the intraoperative injury to neural and vascular structures and failure of the surgery. We have countered a rare intraoperative complication of guidewire breakage during a PELD procedure, as far as we know, this has not been reported previously, and we wish to draw attention to this hazard...
November 4, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27843677/commentary-on-laminectomy-plus-fusion-versus-laminectomy-alone-for-lumbar-spondylolisthesis-by-ghogawala-z-dziura-j-butler-we-dai-f-terrin-n-magge-sn-et-al-nejm-2016-374-15-1424-34
#6
Nancy E Epstein
BACKGROUND: How does an article involving only 66 patients randomized into two spinal surgical groups get into the New England Journal of Medicine? Nevertheless, this one did. The article by Ghogawala et al. entitled Laminectomy plus fusion versus laminectomy alone for lumbar spondylolisthesis, compared the efficacy/outcomes of pedicle/screw/rod instrumented posterolateral lumbar fusions vs. decompressions alone for treating lumbar stenosis with grade I degenerative spondylolisthesis (DS)...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27843676/commentary-on-a-randomized-controlled-trial-of-fusion-surgery-for-lumbar-spinal-stenosis-forsth-p-%C3%A3-lafsson-g-carlsson-t-frost-a-borgstr%C3%A3-m-f-fritzell-p-et-al-n-eng-j-med-2016-374-1414-23
#7
Nancy E Epstein
BACKGROUND: This article by Forsth et al. published in the New England Journal of Medicine entitled A randomized controlled trial of fusion surgery for lumbar spinal stenosis determined that decompressions alone vs. decompressions/fusions were equally effective in treating 1-2 level spinal stensois with/without degenerative spondylolisthesis (DS). Additionally, decompression alone reduced the perioperative morbidity, while reducuing the length of hospital stay (LOS), operative time, and surgical costs...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27829938/midline-lumbar-fusion-using-cortical-bone-trajectory-screws-preliminary-report
#8
Mateusz Bielecki, Przemysław Kunert, Marek Prokopienko, Arkadiusz Nowak, Tomasz Czernicki, Andrzej Marchel
INTRODUCTION: Midline lumbar fusion (MIDLF) using cortical bone trajectory is an alternative method of transpedicular spinal fusion for degenerative disease. The new entry points' location and screwdriving direction allow the approach-related morbidity to be reduced. AIM: To present our preliminary experience with the MIDLF technique on the first 5 patients with lumbar degenerative disease and with follow-up of at least 6 months. MATERIAL AND METHODS: Retrospective analysis was performed on the first 5 patients with foraminal (4) or central (1) stenosis operated on between December 2014 and February 2015...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/27801521/surgical-options-for-lumbar-spinal-stenosis
#9
REVIEW
Gustavo C Machado, Paulo H Ferreira, Rafael Ij Yoo, Ian A Harris, Marina B Pinheiro, Bart W Koes, Maurits W van Tulder, Magdalena Rzewuska, Christopher G Maher, Manuela L Ferreira
BACKGROUND: Hospital charges for lumbar spinal stenosis have increased significantly worldwide in recent times, with great variation in the costs and rates of different surgical procedures. There have also been significant increases in the rate of complex fusion and the use of spinal spacer implants compared to that of traditional decompression surgery, even though the former is known to incur costs up to three times higher. Moreover, the superiority of these new surgical procedures over traditional decompression surgery is still unclear...
November 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27793759/objective-measurement-of-free-living-physical-activity-performance-in-lumbar-spinal-stenosis-are-physical-activity-guidelines-being-met
#10
Justin Norden, Aman Sinha, Matthew Smuck, Christy Tomkins-Lane, Richard Hu
BACKGROUND: Research suggests that people with lumbar spinal stenosis (LSS) would benefit from increased physical activity. Yet, to date we do not have disease specific activity guidelines for LSS, and the nature of free-living physical activity (performance) in LSS remains unknown. LSS care providers could endorse the 2008 United States Physical Activity Guidelines, however, we do not know if this is realistic. The goal of this study was to determine the proportion of individuals with LSS meeting the 2008 Guidelines...
October 25, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27792113/surgical-strategy-for-spinal-dumbbell-tumors-a-new-classification-and-surgical-outcomes
#11
Tong Liu, Hui Liu, Jian-Ning Zhang, Tao Zhu
STUDY DESIGN: One hundred and twenty-four patients with spinal dumbbell tumors were analyzed retrospectively using a new classification. OBJECTIVES: To recommend a novel classification of spinal dumbbell tumors based on the characteristics of surgical approach. SUMMARY OF BACKGROUND DATA: Current classifications of cervical dumbbell tumor are excessively convoluted with an impractical number of variables or lack of quantitative indicators for the choice of surgical approach, and there are few classifications described in literature which related to thoracic or lumbar dumbbell tumors...
October 25, 2016: Spine
https://www.readbyqxmd.com/read/27785474/idiopathic-and-normal-lateral-lumbar-curves-muscle-effects-interpreted-by-12th-rib-length-asymmetry-with-pathomechanic-implications-for-lumbar-idiopathic-scoliosis
#12
Theodoros B Grivas, R Geoffrey Burwell, Vasileios Kechagias, Christina Mazioti, Apostolos Fountas, Dimitra Kolovou, Evangelos Christodoulou
BACKGROUND: The historical view of scoliosis as a primary rotation deformity led to debate about the pathomechanic role of paravertebral muscles; particularly multifidus, thought by some to be scoliogenic, counteracting, uncertain, or unimportant. Here, we address lateral lumbar curves (LLC) and suggest a pathomechanic role for quadrates lumborum, (QL) in the light of a new finding, namely of 12th rib bilateral length asymmetry associated with idiopathic and small non-scoliosis LLC. METHODS: Group 1: The postero-anterior spinal radiographs of 14 children (girls 9, boys 5) aged 9-18, median age 13 years, with right lumbar idiopathic scoliosis (IS) and right LLC less that 10°, were studied...
2016: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/27775931/sublaminar-decompression-a-new-technique-for-spinal-canal-decompression-in-the-treatment-of-stenosis-in-degenerative-spinal-conditions
#13
Khaled M Kebaish, Benjamin D Elder, Sheng-Fu L Lo, Timothy F Witham
STUDY DESIGN: Technical report and case illustration. OBJECTIVE: To review the rationale and steps for a sublaminar decompression in the setting of adult deformity surgery and in degenerative spondylosis. SUMMARY OF BACKGROUND DATA: Several variations of lumbar laminotomy and posterior decompressions have been reported, although these are primarily in the setting of isolated lumbar stenosis, and often focus on treatment of central stenosis...
October 21, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27765708/slump-sitting-x-ray-of-the-lumbar-spine-is-superior-to-the-conventional-flexion-view-in-assessing-lumbar-spine-instability
#14
Hwee Weng Dennis Hey, Eugene Tze-Chun Lau, Joel-Louis Lim, Denise Ai-Wen Choong, Chuen-Seng Tan, Gabriel Ka-Po Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Flexion radiographs have been used to identify cases of spinal instability. However, current methods are not standardized and are not sufficiently sensitive or specific to identify instability. PURPOSE: This study aimed to introduce a new slump sitting method for performing lumbar spine flexion radiographs and comparison of the angular range of motions (ROMs) and displacements between the conventional method and this new method. STUDY DESIGN: This study used is a prospective study on radiological evaluation of the lumbar spine flexion ROMs and displacements using dynamic radiographs...
October 17, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27716965/normalizing-gdnf-expression-in-the-spinal-cord-alleviates-cutaneous-hyperalgesia-but-not-ongoing-pain-in-a-rat-model-of-bone-cancer-pain
#15
Zhuofeng Ding, Wei Xu, Jie Zhang, Wangyuan Zou, Qulian Guo, Changsheng Huang, Chang Liu, Tao Zhong, Jun-Ming Zhang, Zongbin Song
Bone cancer pain (BCP) is the most common complication in patients with bone cancer. Glial cell line-derived neurotrophic factor (GDNF) is believed to be involved in chronic pain conditions. In this article, the expression and roles of GDNF were studied in a rat model of BCP induced by tibia injection of Walker 256 rat mammary gland carcinoma cells. Significant mechanical and thermal hyperalgesia and ongoing pain were observed beginning as early as day 5 post injection. The expression level of GDNF protein examined on day 16 after tibia injection was decreased in the L3 dorsal root ganglion (DRG) and lumbar spinal cord, but not in other spinal levels or the anterior cingulate cortex...
January 15, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27688311/predictors-of-persistent-disability-and-back-pain-in-older-adults-with-a-new-episode-of-care-for-back-pain
#16
Sean D Rundell, Karen J Sherman, Patrick J Heagerty, Charles N Mock, Nathan J Dettori, Bryan A Comstock, Andrew L Avins, Srdjan S Nedeljkovic, David R Nerenz, Jeffrey G Jarvik
OBJECTIVE:  To identify predictors of persistent disability and back pain in older adults. DESIGN:  Prospective cohort study. SETTING:  Back pain outcomes using longitudinal data registry. SUBJECTS:  Five thousand two hundred twenty adults age 65 years and older with a new primary care visit for back pain. METHODS:  Baseline measurements included: demographics, health, and back pain characteristics...
September 28, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27687289/progression-of-motor-neuron-disease-is-accelerated-and-the-ability-to-recover-is-compromised-with-advanced-age-in-rnls8-mice
#17
Krista J Spiller, Clark R Restrepo, Tahiyana Khan, Anna M Stieber, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee
In order to treat progressive paralysis in ALS patients, it is critical to develop a mouse that closely models human ALS in both pathology and also in the timing of these events. We have recently generated new TDP-43 bigenic mice (called rNLS8) with doxycycline (Dox)-suppressible expression of human TDP-43 (hTDP-43) harboring a defective nuclear localization signal (hTDP-43∆NLS) under the control of the NEFH promoter. Our previous studies characterized the pathology and disease course in young rNLS8 mice following induction of neuronal hTDP-43ΔNLS...
September 29, 2016: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/27677036/biomechanical-strategies-of-spine-pelvis-and-lower-limbs-to-achieve-the-stand-to-sit-task-a-kinematic-study-with-tridimensional-motion-analysis
#18
Emmanuelle Chaleat-Valayer, Agnès Troncy, Marion Montané, Soline Bellaiche, Eric Berthonnaud
OBJECTIVE: The goal of this preliminary study is to analyze the biomechanical strategies of spine, pelvis and lower limbs (LL) with tridimensional motion analysis during stand-to-sit task, an understudied movement in the literature, however, source of questioning in clinical practice. OBSERVATIONS: One female and one male, healthy participants, (respectively 28 and 48 years old) were included without history of pathology and with normal pelvic incidences. Participants performed stand-to-sit movements on a stool without using their hands...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27677031/three-dimensional-reconstructions-of-lenke-1a-curves
#19
Jean-Claude Bernard, Eric Berthonnaud, Nuria Rodriguez-Martinez, Julie Deceuninck, Emmanuelle Chaleat-Valayer
OBJECTIVE: Three-dimensional imaging was performed to identify if Lenke 1A curves could be reclassified in subgroups to improved orthopedic or surgical treatment of adolescent idiopathic scoliosis. It seems that multitude of 3D reconstructions can exist in Lenke 1A curves. With his classification Lenke introduces new parameters in radiographic analysis of idiopathic scoliosis like frontal lumbar and thoracic sagittal modifiers. Scoliosis is defined as a three dimensional deformity in frontal, sagittal and horizontal plane...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676973/sustainable-reduction-in-the-occurrence-of-falls-in-a-parkinson-s-patient-who-followed-an-intensive-and-specific-rehabilitation-program-to-recalibrate-verticality-perception
#20
Laure Mathevon, Nicolas Leroux, Céline Piscicelli, Emmanuelle Clarac, Shenhao Dai, Patrice Davoine, Paul Krack, Dominic Perennou
OBJECTIVE: To take care of postural disorders is a major issue in Parkinson's disease (PD). We present a documented observation suggesting the existence of a biased representation of verticality in PD, resulting in a severe retropulsion and recurrent falls. A rehabilitation program aimed to modulate verticality perception dramatically improved the postural perception of the vertical, trunk posture and balance abilities, and reduced retropulsion as well as lastingly fall frequency. OBSERVATIONS: A 68 year-old patient with Parkinson's disease fall backward 3 times a day...
September 2016: Annals of Physical and Rehabilitation Medicine
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