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https://www.readbyqxmd.com/read/29792376/somatic-ace-regulates-self-renewal-of-mouse-spermatogonial-stem-cells-via-the-mapk-signaling-pathway
#1
Tingting Gao, Xin Zhao, Chenchen Liu, Binbin Shao, Xi Zhang, Kai Li, Jinyang Cai, Su Wang, Xiaoyan Huang
Spermatogonial stem cell (SSC) self-renewal is an indispensable part of spermatogenesis. Angiotensin I-converting enzyme (ACE) is a zinc dipeptidyl carboxypeptidase that plays a critical role in regulation of the renin-angiotensin system. Here, we used RT-PCR and Western blot analysis to confirm that somatic ACE (sACE) but not testicular ACE (tACE) is highly expressed in mouse testis before postpartum day 7 and in cultured SSCs. Our results revealed that sACE is located on the membrane of SSCs. Treating cultured SSCs with the ACE competitive inhibitor captopril was found to inhibit sACE activity, and significantly reduced the proliferation rate of SSCs...
May 24, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29792129/exploring-intimate-partner-violence-before-during-and-after-pregnancy-in-bangladesh
#2
Md Jahirul Islam, Lisa Broidy, Paul Mazerolle, Kathleen Baird, Nurunnahar Mazumder
Intimate partner violence (IPV) against pregnant or postpartum women is known to have multiple detrimental effects on women and their children. Although results from past research suggest much continuity in trajectories of IPV, it is unclear whether pregnancy interrupts or augments these patterns. Little is known about how physical, sexual, and psychological IPV change and overlap throughout a woman's transition to parenthood. Relying on population-based data, this study examines the prevalence, co-occurring nature, and the changing patterns of physical, sexual, and psychological IPV before, during, and after pregnancy in Bangladesh...
May 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29791012/a-systematic-mixed-studies-review-of-women-s-experiences-of-perineal-trauma-sustained-during-childbirth
#3
REVIEW
Rebecca Crookall, Gillian Fowler, Caroline Wood, Pauline Slade
AIM: To explore the quantitative/qualitative literature on women's experiences of perineal trauma sustained during childbirth and the impact it may have on psychological/emotional wellbeing BACKGROUND: Obstetric complications during childbirth can be a risk factor for postpartum psychological distress. Perineal trauma is one of the most frequent obstetric complications and it is important to understand any impact on psychological/emotional wellbeing. DESIGN: A convergent qualitative design using a hybrid deductive-inductive thematic synthesis approach to data transformation was used...
May 23, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29790945/the-effects-of-protein-supplementation-of-fall-calving-beef-cows-on-pre-and-postpartum-plasma-insulin-glucose-and-igf-i-and-postnatal-growth-and-plasma-insulin-and-igf-i-of-calves
#4
Kyle J McLean, Brit H Boehmer, Leon J Spicer, Robert P Wettemann
Fall calving (September to October) cows (n = 189 calvings in 5 replications; body weight [BW] = 626 ± 6 kg, body condition score [BCS] = 4.76 ± 0.06) grazing native dormant range were used to determine the effects of protein supplementation on performance and endocrine function of cows and calves. Cows were individually fed either a control (CON; 1.82 kg/d of 38% crude protein [CP]) or restricted (RES; 0.2 kg/d of 8% CP) protein supplement from mid-November to mid-March for 6 consecutive years. During each year, cows were reassigned dietary treatments according to calving date and BCS, and half of the CON and half of the RES cows remained on the same diets as the previous year and the other halves were assigned to the other diet...
May 22, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29790850/-the-practical-considerations-of-antidepressant-use-during-pregnancy-and-breastfeeding
#5
Peter Dome, Gabor Faludi
Main indications of antidepressants (ADs) as major depressive disorder (MDD) and different kinds of anxiety disorders are quite prevalent during pregnancy and the postpartum period. Due to the possible hazards of in utero and breast milk exposition of ADs, both psychiatrists and mothers frequently have concerns about the use of ADs during the periods of pregnancy and breastfeeding. However, we should also bear in mind that affective disorders left untreated during these periods are also associated with health risks for the mother and the baby as well...
March 2018: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29789964/caring-for-women-with-multiple-sclerosis-across-the-lifespan
#6
REVIEW
Kelsey Rankin, Riley Bove
PURPOSE OF REVIEW: Caring for women with multiple sclerosis (MS), whose first symptoms typically begin during the childbearing years, requires a comprehensive approach to management across a range of reproductive exposures, and beyond through menopause. RECENT FINDINGS: This article summarizes what is known about the disease course in women with MS, how it differs from men, and the current state of knowledge regarding effects of reproductive exposures (menarche, childbearing, menopause) on MS-related inflammation and neurodegeneration...
May 23, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29788970/an-autopsy-case-of-peripheral-t-cell-lymphoma-occurring-in-a-postpartum-woman-a-unique-case-suggesting-changes-in-the-immunocharacteristics-of-lymphoma-cells-before-and-after-delivery
#7
Kenichi Mizutani, Sohsuke Yamada, Xin Guo, Chizuru Futatsuya, Motona Kumagai, Akihiro Shioya, Akane Aikawa, Satoko Nakada, Nozomu Kurose, Hiroshi Minato, Takayuki Nojima
BACKGROUND: The occurrence of malignant lymphoma after delivery is an extremely rare event. Although several cases of Hodgkin lymphoma and B cell lymphoma and a few cases of peripheral T cell lymphoma (PTCL) after delivery have been reported, there are no report of autopsy cases of PTCL in the puerperal period. CASE PRESENTATION: A 32-year-old Japanese woman with a past medical history of atopic dermatitis and bronchial asthma presented with generalized eruptions four days after the delivery of her first child; generalized skin induration and lymphadenopathy subsequently emerged...
May 22, 2018: Diagnostic Pathology
https://www.readbyqxmd.com/read/29788769/audit-of-intrapartum-care-based-on-the-national-guideline-for-midwifery-and-birth-services
#8
Sonia Minooee, Masoumeh Simbar, Zohreh Sheikhan, Hamid Alavi Majd
Providing high-quality maternity care is a worldwide health concern that necessitates regular assessment of intrapartum practice. In an observational study, we aimed to audit intrapartum care based on the National Guideline for Midwifery and Birth Services. Using quota sampling, a total of 200 pregnant women, admitted for normal vaginal delivery, were recruited from four educational hospitals in Tehran, Iran. An observational checklist was developed based on the national guideline to assess the quality of provided care...
January 1, 2018: Evaluation & the Health Professions
https://www.readbyqxmd.com/read/29788426/progression-of-low-grade-glioma-during-pregnancy-with-subsequent-regression-postpartum-without-treatment-a-case-report
#9
Amar S Shah, Lisa K Nicoletti, Elvisa Kurtovic, Christina I Tsien, Tammie L S Benzinger, Michael R Chicoine
BACKGROUND AND IMPORTANCE: This report illustrates a case of a low-grade glioma that showed significant disease progression during pregnancy, and then subsequent regression spontaneously in the postpartum period without treatment. This is a rare case of spontaneous glioma regression in the postpartum period, and may suggest underlying mechanisms of hormonal influences upon glioma progression. CLINICAL PRESENTATION: The patient is a 27-yr-old female who underwent placement of a right-sided ventriculoperitoneal shunt for aqueductal stenosis at 8 wk of age...
May 21, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29787690/breastfeeding-practices-among-hispanic-and-non-hispanic-women-at-the-postpartum-visit
#10
Cameryn C Garrett, Michelle Azimov, Khozema Campwala, Maria Sarmiento, Kristen Faye Linton
BACKGROUND: Breastfeeding is an active area in public health advocacy. Despite documented benefits for infants and mothers, exclusive breastfeeding is not universal. Ethnicity, among other variables, has been shown to influence breastfeeding practice. Research aim: Our study aimed to determine which variables are associated with infant feeding patterns at the postpartum visit; compare the sociodemographic variables associated with infant feeding patterns between Hispanic and non-Hispanic mothers; and determine the odds of exclusive breastfeeding, mixed feeding, and exclusive formula feeding associated with sociodemographic characteristics...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29787686/social-support-for-breastfeeding-in-the-era-of-mhealth-a-content-analysis
#11
Jennifer M Schindler-Ruwisch, Amira Roess, Rebecca C Robert, Melissa A Napolitano, Shawn Chiang
BACKGROUND: Several barriers to successful breastfeeding exist, including a lack of support from peers or professionals. With the emergence of mobile health (mHealth) tools to provide additional breastfeeding support, a more thorough review of social support resources was needed. Research Aim: The aim of this study was to determine mHealth breastfeeding support resources and characterize the type of social support they provide. METHODS: A content analysis of mHealth programs ( n = 65), including text messaging ( n = 12) and mobile applications ( n = 53), was conducted on the basis of searches of the iTunes and Google Play stores ( n = 50) and PubMed, the Cumulative Index of Nursing and Allied Health, and American Business Information/INFORM Complete Plus ( n = 15)...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29787682/maternal-perception-of-adequacy-of-mother-s-milk-among-mothers-giving-birth-at-a-teaching-hospital-in-sri-lanka
#12
Ranmali Rodrigo, Asiri Rodrigo, Nisansala Liyanage, Wathsala Hatahagoda, Uthpala Hewavitharana
BACKGROUND: Sri Lanka boasts high rates of early and exclusive breastfeeding. Perceived inadequacy of milk, a global problem, is the main cause for early cessation of breastfeeding. Research Aims: The aims of this study are to (a) determine the prevalence, (b) identify the risk factors, and (c) ascertain the association that maternal psychological distress has with perceived inadequacy of milk (PIM), among mothers during the early postpartum period. Identifying and addressing modifiable risk factors for PIM may improve mothers' satisfaction with breastfeeding...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29787638/incidence-trends-and-severity-of-primary-postpartum-haemorrhage-in-australia-a-population-based-study-using-victorian-perinatal-data-collection-data-for-764-244-births
#13
Margaret Flood, Susan J McDonald, Wendy Pollock, Fiona Cullinane, Mary-Ann Davey
BACKGROUND: Increasing incidence and severity of postpartum haemorrhage, together with postpartum haemorrhage-associated morbidities, have been reported in many high-resource countries. In-depth analysis of such factors in Victorian births since 2002 was lacking. AIMS: Our aim was to determine the incidence and trends for primary postpartum haemorrhage (World Health Organization and International Classification of Diseases 10th revision, Australian Modification definitions) for all confinements in Victoria, Australia, for the years 2003-2013 and the incidence and trends for severe postpartum haemorrhage (≥1500 mL) for 2009-2013...
May 22, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29787622/mother-to-child-transmission-of-hiv-in-australia-and-other-high-income-countries-trends-in-perinatal-exposure-demography-and-uptake-of-prevention-strategies
#14
REVIEW
Kelly O'Donovan, Theophilus I Emeto
Virtual elimination of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) is a global target. A review of the literature was conducted using medical databases and health department websites to examine the current trends related to perinatal HIV exposure and MTCT in Australia in comparison with other high-income countries (HICs). The review discusses the uptake of prevention strategies and barriers that impede MTCT prevention. The literature suggests an increase in the numbers of HIV-exposed deliveries, but a marked decline in the rates of MTCT within HICs...
May 22, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29787407/identifying-barriers-to-implementation-of-the-national-partnership-for-maternal-safety-obstetric-hemorrhage-bundle-at-a-tertiary-center-utilization-of-the-delphi-method
#15
Annemaria De Tina, Anthony Chau, Daniela A Carusi, Julian N Robinson, Lawrence C Tsen, Michaela K Farber
BACKGROUND: In 2015, the National Partnership for Maternal Safety (NPMS) developed an obstetric hemorrhage consensus bundle to provide birthing facilities in the United States with consistent, validated practice guidelines for postpartum hemorrhage management. The process of implementing each bundle element at a large tertiary labor and delivery unit has not been described; we sought to identify practice deficiencies and perceived barriers to bundle implementation among multidisciplinary providers...
May 21, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29787355/effect-of-lavender-cream-with-or-without-footbath-on-sleep-quality-and-fatigue-in-pregnancy-and-postpartum-a-randomized-controlled-trial
#16
Fatemeh Effati-Daryani, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirghafourvand, Mohsen Taghizadeh, Reza Bekhradi, Somayeh Zarei
BACKGROUND: Sleep disturbance and fatigue are frequent complaints during pregnancy and postpartum. We assessed the effectiveness of Lavender cream and footbath on sleep quality and fatigue in pregnancy and postpartum. METHODS: In this trial, 141 women with sleep disturbance at 25-28 weeks gestation were recruited from public health centers in Tabriz, Iran, from May 2013 until January 2014 and randomized into one of three groups receiving: Lavender and footbath, Lavender alone, or placebo cream...
May 22, 2018: Women & Health
https://www.readbyqxmd.com/read/29786116/is-childbirth-induced-ptsd-associated-with-low-maternal-attachment
#17
Sharon Dekel, Freya Thiel, Gabriella Dishy, Alyssa L Ashenfarb
Few studies examined maternal attachment in childbirth-related postpartum posttraumatic stress disorder (PP-PTSD). We studied 685 postpartum women, assessing for PP-PTSD, non-childbirth PTSD, maternal attachment, pre-birth, birth, and post-birth factors. Attachment was lower in PP-PTSD than in non-childbirth PTSD and no PP-PTSD. Hierarchical regression showed that PP-PTSD predicted less maternal attachment above and beyond pre-birth psychiatric conditions, acute distress in birth, and lack of breastfeeding...
May 21, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29785905/hepatic-sirt3-expression-declines-postpartum-in-dairy-goats
#18
Lei Liu, Li Yao, Tao Peng, Lixin Wen, Wenjie Cai, Xinglin Jia, Jianhua He
The experiments reported in this research communication aimed to plot the expression pattern of Sirt3, a master regulator of energy metabolism and antioxidation defence, in the liver of dairy goats during perinatal period. Ten healthy dairy goats in late pregnancy were chosen, and needle biopsy was applied to collect liver samples at 1-week intervals. Protein levels of hepatic Sirt3 were analysed by western-blotting. Serum enzyme activities of manganese superoxide dismutase (Mn-SOD) and non-esterified fatty acids (NEFA) levels were measured, and their correlation with Sirt3 mRNA levels was also estimated...
May 2018: Journal of Dairy Research
https://www.readbyqxmd.com/read/29785890/family-networks-and-healthy-behaviour-evidence-from-nepal
#19
Jolene Skordis, Noemi Pace, Marcos Vera-Hernandez, Imran Rasul, Emla Fitzsimons, David Osrin, Dharma Manandhar, Anthony Costello
Models of household decision-making commonly focus on nuclear family members as primary decision-makers. If extended families shape the objectives and constraints of households, then neglecting the role of this network may lead to an incomplete understanding of health-seeking behaviour. Understanding the decision-making processes behind care-seeking may improve behaviour change interventions, better intervention targeting and support health-related development goals. This paper uses data from a cluster randomised trial of a participatory learning and action cycle (PLA) through women's groups, to assess the role of extended family networks as a determinant of gains in health knowledge and health practice...
May 22, 2018: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/29785548/operative-vaginal-delivery-in-case-of-persistent-occiput-posterior-position-after-manual-rotation-failure-a-6-month-follow-up-on-pelvic-floor-function
#20
Paul Guerby, Olivier Parant, Elodie Chantalat, Christophe Vayssiere, Fabien Vidal
PURPOSE: To compare the short- and long-term perineal consequences (at 6 months postpartum) and short-term neonatal consequences of instrumental rotation (IR) to those induced by assisted delivery (AD) in the occiput posterior (OP) position, in case of manual rotation failure. METHODS: A prospective observational cohort study; tertiary referral hospital including all women presenting with persistent OP position who delivered vaginally after manual rotation failure with attempted IR or AD in OP position from September 2015 to October 2016...
May 21, 2018: Archives of Gynecology and Obstetrics
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