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https://www.readbyqxmd.com/read/28077473/a-joint-ers-ats-policy-statement-what-constitutes-an-adverse-health-effect-of-air-pollution-an-analytical-framework
#1
George D Thurston, Howard Kipen, Isabella Annesi-Maesano, John Balmes, Robert D Brook, Kevin Cromar, Sara De Matteis, Francesco Forastiere, Bertil Forsberg, Mark W Frampton, Jonathan Grigg, Dick Heederik, Frank J Kelly, Nino Kuenzli, Robert Laumbach, Annette Peters, Sanjay T Rajagopalan, David Rich, Beate Ritz, Jonathan M Samet, Thomas Sandstrom, Torben Sigsgaard, Jordi Sunyer, Bert Brunekreef
The American Thoracic Society has previously published statements on what constitutes an adverse effect on health of air pollution in 1985 and 2000. We set out to update and broaden these past statements that focused primarily on effects on the respiratory system. Since then, many studies have documented effects of air pollution on other organ systems, such as on the cardiovascular and central nervous systems. In addition, many new biomarkers of effects have been developed and applied in air pollution studies...
January 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28070614/outgroup-alignment-and-modelling-improvements-indicate-that-two-tnfsf13-like-genes-existed-in-the-vertebrate-ancestor
#2
Anthony K Redmond, Rita Pettinello, Helen Dooley
The molecular machinery required for lymphocyte development and differentiation appears to have emerged concomitantly with distinct B- and T-like lymphocyte subsets in the ancestor of all vertebrates. The TNFSF superfamily (TNFSF) members BAFF (TNFSF13/Blys) and APRIL (TNFSF13) are key regulators of B cell development survival, and activation in mammals, but the temporal emergence of these molecules, and their precise relationship to the newly identified TNFSF gene BALM (BAFF and APRIL-like molecule), have not yet been elucidated...
January 9, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28063268/evaluation-of-the-quality-of-herbal-teas-by-dart-tof-ms
#3
Jana Prchalová, František Kovařík, Aleš Rajchl
The paper focuses on the optimization, settings and validation of direct analysis in real time (DART) coupled with time of flight detector (TOF) when used for the evaluation of the quality of selected herbal teas (fennel, chamomile, nettle, linden, peppermint, thyme, lemon balm, marigold, sage, rose hip, St. John's Wort). The ionization mode, the optimal ionization temperature and the type of solvent for sample extraction were optimized. The characteristic compounds of the analysed herbal teas (glycosides, flavonoids, phenolic and terpenic substances, such as chamazulene, anethole, menthol, thymol, salviol, hypericin etc...
January 7, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28034507/zno-films-formed-by-atomic-layer-deposition-as-an-optical-biosensor-platform-for-the-detection-of-grapevine-virus-a-type-proteins
#4
Alla Tereshchenko, Viktoriia Fedorenko, Valentyn Smyntyna, Igor Konup, Anastasiya Konup, Martin Eriksson, Rositsa Yakimova, Arunas Ramanavicius, Sebastien Balme, Mikhael Bechelany
Novel sensitive optical biosensor for determination of Grapevine virus A-type (GVA) proteins (GVA-antigens) has been designed. This biosensor was based on thin films of Zinc Oxide (ZnO) deposited by atomic layer deposition (ALD). The ZnO-based films have demonstrated favorable surface-structural properties for the direct immobilization of antibodies against GVA-antigens in order to form a biosensitive layer sensitive to GVA-antigens. The immobilization was confirmed by intensity changes in the main near band emission (NBE) peak of ZnO and by the formation of intense photoluminescence band, discovered in the visible range around 425nm, caused by the immobilized proteins...
September 23, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27951689/solid-liquid-interface-structure-of-muscovite-mica-in-cscl-and-rbbr-solutions
#5
Stelian Pintea, Wester de Poel, Aryan E F de Jong, Vedran Vonk, Pim van der Asdonk, Jakub Drnec, Olivier Balmes, Helena Isern, Thomas Dufrane, Roberto Felici, Elias Vlieg
The solid-liquid interface formed by single terminated muscovite mica in contact with two different ionic solutions is analyzed using surface X-ray diffraction. Specular and nonspecular crystal truncation rods of freshly cleaved mica immersed in CsCl or RbBr aqueous solution were measured. The half monolayer of the surface potassium ions present after the cleavage is completely replaced by the positive ions (Cs(+) or Rb(+)) from the solution. These ions are located in the ditrigonal surface cavities with small outward relaxations with respect to the bulk potassium position...
December 13, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27939058/a-cleaner-burning-biomass-fuelled-cookstove-intervention-to-prevent-pneumonia-in-children-under-5-years-old-in-rural-malawi-the-cooking-and-pneumonia-study-a-cluster-randomised-controlled-trial
#6
Kevin Mortimer, Chifundo B Ndamala, Andrew W Naunje, Jullita Malava, Cynthia Katundu, William Weston, Deborah Havens, Daniel Pope, Nigel G Bruce, Moffat Nyirenda, Duolao Wang, Amelia Crampin, Jonathan Grigg, John Balmes, Stephen B Gordon
BACKGROUND: WHO estimates exposure to air pollution from cooking with solid fuels is associated with over 4 million premature deaths worldwide every year including half a million children under the age of 5 years from pneumonia. We hypothesised that replacing open fires with cleaner burning biomass-fuelled cookstoves would reduce pneumonia incidence in young children. METHODS: We did a community-level open cluster randomised controlled trial to compare the effects of a cleaner burning biomass-fuelled cookstove intervention to continuation of open fire cooking on pneumonia in children living in two rural districts, Chikhwawa and Karonga, of Malawi...
January 14, 2017: Lancet
https://www.readbyqxmd.com/read/27928571/diffusion-dynamics-of-latex-nanoparticles-coated-with-ssdna-across-a-single-nanopore
#7
Sébastien Balme, Mathilde Lepoitevin, Ludovic F Dumée, Mikhael Bechelany, Jean-Marc Janot
The fundamental understanding of the transport mechanisms of objects across a single nanopore is one key point to develop Coulter counters at the nanoscale for macromolecule or nanoparticle detection. In this area, nanoparticles have been less investigated than biomacromolecules such as DNA or proteins due to their self-aggregation in the presence of salts. In this work, the transport of modified latex nanoparticles across solid-state nanopores was investigated. To prevent their aggregation, their surface was modified with a low molecular weight single strand DNA coating...
December 8, 2016: Soft Matter
https://www.readbyqxmd.com/read/27916478/development-and-external-validation-of-a-model-predicting-death-after-surgery-in-patients-with-a-ruptured-abdominal-aortic-aneurysm-the-dutch-aneurysm-score
#8
G C I von Meijenfeldt, S C van Beek, F Bastos Gonçalves, H J M Verhagen, C J Zeebregts, A C Vahl, W Wisselink, M J van der Laan, R Balm
OBJECTIVE: The decision whether or not to proceed with surgical intervention of a patient with a ruptured abdominal aortic aneurysm (rAAA) is very difficult in daily practice. The primary objective of the present study was to develop and to externally validate a new prediction model: the Dutch Aneurysm Score (DAS). METHODS: With a prospective cohort of 10 hospitals (n = 508) the DAS was developed using a multivariate logistic regression model. Two retrospective cohorts with rAAA patients from two hospitals (n = 373) were used for external validation...
December 1, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27904398/stability-of-rosmarinic-acid-in-aqueous-extracts-from-different-lamiaceae-species-after-in-vitro-digestion-with-human-gastrointestinal-enzymes
#9
Zoran Zorić, Joško Markić, Sandra Pedisić, Viljemka Bučević-Popović, Ivana Generalić-Mekinić, Katarina Grebenar, Tea Kulišić-Bilušić
The present study compares the gastrointestinal stability of rosmarinic acid in aqueous extracts of thyme, winter savory and lemon balm with the stability of pure rosmarinic acid. The stability of rosmarinic acid was detected after two-phase in vitro digestion process (gastric and duodenal) with human gastrointestinal enzymes. The concentration of rosmarinic acid in undigested and digested samples was detected using HPLC-DAD. Results showed that gastrointestinal stability of pure rosmarinic acid was significantly higher than that of rosmarinic acid from plant extracts after both gastric and intestinal phases of digestion...
March 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27825980/expression-and-purification-of-native-and-functional-influenza-a-virus-matrix-2-proton-selective-ion-channel
#10
Elodie Desuzinges Mandon, Aurélien Traversier, Anne Champagne, Lorraine Benier, Stéphane Audebert, Sébastien Balme, Emmanuel Dejean, Manuel Rosa Calatrava, Anass Jawhari
Influenza A virus displays one of the highest infection rates of all human viruses and therefore represents a severe human health threat associated with an important economical challenge. Influenza matrix protein 2 (M2) is a membrane protein of the viral envelope that forms a proton selective ion channel. Here we report the expression and native isolation of full length active M2 without mutations or fusions. The ability of the influenza virus to efficiently infect MDCK cells was used to express native M2 protein...
November 5, 2016: Protein Expression and Purification
https://www.readbyqxmd.com/read/27766304/remission-of-a-long-lasting-sarcoidosis-after-allogeneic-hematopoietic-stem-cell-transplantation-for-acute-myeloid-leukemia
#11
Emmanuelle Ginoux, Diane Kottler, Bruno Anglaret, Brigitte Balme, Claude-Eric Bulabois, François Skowron
No abstract text is available yet for this article.
September 2016: JAAD Case Reports
https://www.readbyqxmd.com/read/27726439/survey-of-international-members-of-the-american-thoracic-society-on-climate-change-and-health
#12
Mona Sarfaty, Jennifer Kreslake, Gary Ewart, Tee L Guidotti, George D Thurston, John R Balmes, Edward W Maibach
The American Thoracic Society (ATS), in collaboration with George Mason University, surveyed international members of the society to assess perceptions, clinical experiences, and preferred policy responses related to global climate change. A recruitment email was sent by the ATS President in October 2015 to 5,013 international members. Subsequently, four reminder emails were sent to nonrespondents. Responses were received from 489 members in 68 countries; the response rate was 9.8%. Half of respondents reported working in countries in Asia (25%) or Europe (25%), with the remainder in South America (18%), North America (Canada and Mexico) (18%), Australia or New Zealand (9%), and Africa (6%)...
October 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27725189/high-risks-of-lung-disease-associated-with-early-life-and-moderate-lifetime-arsenic-exposure-in-northern-chile
#13
Craig Steinmaus, Catterina Ferreccio, Johanna Acevedo, John R Balmes, Jane Liaw, Patricia Troncoso, David C Dauphiné, Anthony Nardone, Allan H Smith
BACKGROUND: Arsenic in drinking water has been associated with increases in lung disease, but information on the long-term impacts of early-life exposure or moderate exposure levels are limited. METHODS: We investigated pulmonary disease and lung function in 795 subjects from three socio-demographically similar areas in northern Chile: Antofagasta, which had a well-described period of high arsenic water concentrations (860μg/L) from 1958 to 1970; Iquique, which had long-term arsenic water concentrations near 60μg/L; and Arica, with long-term water concentrations ≤10μg/L...
December 15, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/27688825/rosmarinic-acid-and-melissa-officinalis-extracts-differently-affect-glioblastoma-cells
#14
Kristina Ramanauskiene, Raimondas Raudonis, Daiva Majiene
Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has cytotoxic effect on glioblastoma cells (LC50 290.5 μM after the incubation of 24 h and LC50 171.3 μM after 48 h)...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/27668911/niehs-50-years-of-advancing-science-improving-lung-health
#15
Veena B Antony, Carrie A Redlich, Kent E Pinkerton, John Balmes, Jack R Harkema
The American Thoracic Society (ATS) celebrates the 50th anniversary of The National institute of Environmental Sciences (NIEHS). The NIEHS has had enormous impact through its focus on research, training and translational science on lung health. It has been an advocate for clean air both in the US and across the world. The cutting edge science funded by the NIEHS has lead to major discoveries that have broadened our understanding of the pathogenesis and treatment for lung disease. Importantly the NIEHS has developed and fostered mechanisms that require cross cutting science across the spectrum of areas of inquiry, bringing together environmental and social scientists with clinicians to bring their expertise on specific areas of investigation...
September 26, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27644983/the-significance-of-petroleum-bitumen-in-ancient-egyptian-mummies
#16
K A Clark, S Ikram, R P Evershed
Mummification was practised in ancient Egypt for more than 3000 years, emerging from initial observations of buried bodies preserved by natural desiccation. The use of organic balms (and other funerary practices) was a later introduction necessitated by more humid burial environments, especially tombs. The dark colour of many mummies led to the assumption that petroleum bitumen (or natural asphalt) was ubiquitous in mummification; however, this has been questioned for more than 100 years. We test this by investigating 91 materials comprising balms, tissues and textiles from 39 mummies dating from ca 3200 BC to AD 395...
October 28, 2016: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/27639568/a-critical-evaluation-of-lymph-node-ratio-in-head-and-neck-cancer
#17
M de Ridder, C C M Marres, L E Smeele, M W M van den Brekel, M Hauptmann, A J M Balm, M L F van Velthuysen
In head and neck squamous cell carcinoma (HNSCC), the search for better prognostic factors beyond TNM-stage is ongoing. Lymph node ratio (LNR) (positive lymph nodes/total lymph nodes) is gaining interest in view of its potential prognostic significance. All HNSCC patients at the Netherlands Cancer Institute undergoing neck dissection for lymph node metastases in the neck region between 2002 and 2012 (n = 176) were included. Based on a protocol change in specimen processing, the cohort was subdivided in two distinct consecutive periods (pre and post 2007)...
December 2016: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/27620926/melissa-officinalis-l-a-review-study-with-an-antioxidant-prospective
#18
Sepide Miraj, Rafieian-Kopaei, Sara Kiani
Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail...
September 11, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27576581/liquid-and-vapour-phase-antifungal-activities-of-essential-oils-against-candida-albicans-and-non-albicans-candida
#19
Narcisa Mandras, Antonia Nostro, Janira Roana, Daniela Scalas, Giuliana Banche, Valeria Ghisetti, Simonetta Del Re, Giacomo Fucale, Anna Maria Cuffini, Vivian Tullio
BACKGROUND: The management of Candida infections faces many problems, such as a limited number of antifungal drugs, toxicity, resistance of Candida to commonly antifungal drugs, relapse of Candida infections, and the high cost of antifungal drugs. Though azole antifungal agents and derivatives continue to dominate as drugs of choice against Candida infections, there are many available data referring to the anticandidal activity of essential oils. Since we have previous observed a good antimicrobial activity of some essential oils against filamentous fungi, the aim of this study was to extend the research to evaluate the activity of the same oils on Candida albicans, C...
August 30, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27558090/biomechanical-imaging-markers-as-predictors-of-abdominal-aortic-aneurysm-growth-or-rupture-a-systematic-review
#20
REVIEW
R Indrakusuma, H Jalalzadeh, R N Planken, H A Marquering, D A Legemate, M J W Koelemay, R Balm
OBJECTIVES: Biomechanical characteristics, such as wall stress, are important in the pathogenesis of abdominal aortic aneurysms (AAA) and can be visualised and quantified using imaging techniques. This systematic review aims to present an overview of all biomechanical imaging markers that have been studied in relation to AAA growth and rupture. METHODS: This systematic review followed the PRISMA guidelines. A search in Medline, Embase, and the Cochrane Library identified 1503 potentially relevant articles...
October 2016: European Journal of Vascular and Endovascular Surgery
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