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https://www.readbyqxmd.com/read/27836956/an-association-of-particulate-air-pollution-and-traffic-exposure-with-mortality-after-lung-transplantation-in-europe
#1
David Ruttens, Stijn E Verleden, Esmée M Bijnens, Ellen Winckelmans, Jens Gottlieb, Gregor Warnecke, Federica Meloni, Monica Morosini, Wim Van Der Bij, Erik A Verschuuren, Urte Sommerwerck, Gerhard Weinreich, Markus Kamler, Antonio Roman, Susana Gomez-Olles, Cristina Berastegui, Christian Benden, Are Martin Holm, Martin Iversen, Hans Henrik Schultz, Bart Luijk, Erik-Jan Oudijk, Johanna M Kwakkel-van Erp, Peter Jaksch, Walter Klepetko, Nikolaus Kneidinger, Claus Neurohr, Paul Corris, Andrew J Fisher, James Lordan, Gerard Meachery, Davide Piloni, Elly Vandermeulen, Hannelore Bellon, Barbara Hoffmann, Danielle Vienneau, Gerard Hoek, Kees de Hoogh, Benoit Nemery, Geert M Verleden, Robin Vos, Tim S Nawrot, Bart M Vanaudenaerde
Air pollution from road traffic is a serious health risk, especially for susceptible individuals. Single-centre studies showed an association with chronic lung allograft dysfunction (CLAD) and survival after lung transplantation, but there are no large studies.13 lung transplant centres in 10 European countries created a cohort of 5707 patients. For each patient, we quantified residential particulate matter with aerodynamic diameter ≤10 µm (PM10) by land use regression models, and the traffic exposure by quantifying total road length within buffer zones around the home addresses of patients and distance to a major road or freeway...
November 11, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/27726086/baseline-seasonal-investigation-of-nutrients-and-trace-metals-in-surface-waters-and-sediments-along-the-saigon-river-basin-impacted-by-the-megacity-of-ho-chi-minh-vietnam
#2
Emilie Strady, Vu Bich Hanh Dang, Julien Némery, Stéphane Guédron, Quoc Tuc Dinh, Hervé Denis, Phuoc Dan Nguyen
The Saigon River, Southern Vietnam, crosses one of the most dynamic developing Megacity in Southeast Asia: Ho Chi Minh City (HCMC). The increased economic, industrial, and domestic developments may affect the environmental quality of water and halieutic resources. In this study, we evaluated the seasonal (dry and wet seasons) biogeochemical state of the Saigon River during two snapshot campaigns conducted along the river basin upstream from HCMC; the Saigon River was characterized by slightly acidic (pH 5.7-7...
October 10, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27562651/assessment-of-personality-related-levels-of-functioning-a-pilot-study-of-clinical-assessment-of-the-dsm-5-level-of-personality-functioning-based-on-a-semi-structured-interview
#3
Birgitte Thylstrup, Sebastian Simonsen, Caroline Nemery, Erik Simonsen, Jane Fjernestad Noll, Mikkel Wanting Myatt, Morten Hesse
BACKGROUND: The personality disorder categories in the Diagnostic and Statistical Manual of Mental Disorders IV have been extensively criticized, and there is a growing consensus that personality pathology should be represented dimensionally rather than categorically. The aim of this pilot study was to test the Clinical Assessment of the Level of Personality Functioning Scale, a semi-structured clinical interview, designed to assess the Level of Personality Functioning Scale of the DSM-5 (Section III) by applying strategies similar to what characterizes assessments in clinical practice...
2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27550908/asbestos-bodies-in-bronchoalveolar-lavage-in-the-21st-century-a-time-trend-analysis-in-a-clinical-population
#4
Valerie Nuyts, Hadewijch Vanhooren, Sarah Begyn, Kristiaan Nackaerts, Benoit Nemery
OBJECTIVES: Asbestos bodies (AB) in bronchoalveolar lavage (BAL) can be detected by light microscopy and their concentration is indicative of past cumulative asbestos exposure. We assessed clinical and exposure characteristics, as well as possible time trends, among patients in whom AB had been quantified in BAL. METHODS: BAL samples obtained from 578 participants between January 1997 and December 2014 were available for analysis. The processing of samples and the microscopic analysis were performed by a single expert and 76% of samples came from a single tertiary care hospital, allowing clinical and exposure data to be extracted from patient files...
August 22, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27346740/respiratory-medication-sales-and-urban-air-pollution-in-brussels-2005-to-2011
#5
Lidia Casas, Koen Simons, Tim S Nawrot, Olivier Brasseur, Priscilla Declerck, Ronald Buyl, Danny Coomans, Benoit Nemery, An Van Nieuwenhuyse
BACKGROUND: We investigated the associations between daily sales of respiratory medication and air pollutants in the Brussels-Capital Region between 2005 and 2011. METHODS: We used over-dispersed Poisson Generalized Linear Models to regress daily individual reimbursement data of prescribed asthma and COPD medication from the social security database against each subject's residential exposure to outdoor particulate matter (PM10) or NO2 estimated, by interpolation from monitoring stations...
September 2016: Environment International
https://www.readbyqxmd.com/read/27345299/nociceptive-and-sympathetic-innervations-in-the-abaxial-part-of-the-cranial-horn-of-the-equine-medial-meniscus-an-immunohistochemical-approach
#6
Elodie Nemery, Annick Gabriel, Joëlle Piret, Nadine Antoine
In athletic horses, diseases leading to lameness are of great importance due to the loss of performance and the resultant economic concerns. Although stifle lesions are frequent in the hindlimb, due to the large size and complexity of the joint, and although meniscal tears have been identified as the most common soft tissue injuries in this joint, little is known about the mechanism that causes the painful sensation and thus the lameness. The aim of our study was to highlight any peripheral fibres involved in meniscal nociception in five macroscopically sound cranial horns of the equine medial meniscus, which has been one of the most common sites reported for equine meniscal injuries...
December 2016: Journal of Anatomy
https://www.readbyqxmd.com/read/27167124/health-impact-assessment-of-a-predicted-air-quality-change-by-moving-traffic-from-an-urban-ring-road-into-a-tunnel-the-case-of-antwerp-belgium
#7
Daan Van Brusselen, Wouter Arrazola de Oñate, Bino Maiheu, Stijn Vranckx, Wouter Lefebvre, Stijn Janssen, Tim S Nawrot, Ben Nemery, Dirk Avonts
BACKGROUND: The Antwerp ring road has a traffic density of 300,000 vehicles per day and borders the city center. The 'Ringland project' aims to change the current 'open air ring road' into a 'filtered tunneled ring road', putting the entire urban ring road into a tunnel and thus filtering air pollution. We conducted a health impact assessment (HIA) to quantify the possible benefit of a 'filtered tunneled ring road', as compared to the 'open air ring road' scenario, on air quality and its long-term health effects...
2016: PloS One
https://www.readbyqxmd.com/read/27126687/neuro-immune-interactions-in-chemical-induced-airway-hyperreactivity
#8
Fien C Devos, Brett Boonen, Yeranddy A Alpizar, Tania Maes, Valérie Hox, Sven Seys, Lore Pollaris, Adrian Liston, Benoit Nemery, Karel Talavera, Peter H M Hoet, Jeroen A J Vanoirbeek
Asthma may be induced by chemical sensitisers, via mechanisms that are still poorly understood. This type of asthma is characterised by airway hyperreactivity (AHR) and little airway inflammation. Since potent chemical sensitisers, such as toluene-2,4-diisocyanate (TDI), are also sensory irritants, it is suggested that chemical-induced asthma relies on neuro-immune mechanisms.We investigated the involvement of transient receptor potential channels (TRP) A1 and V1, major chemosensors in the airways, and mast cells, known for their ability to communicate with sensory nerves, in chemical-induced AHR...
August 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/27088280/microtia-in-cornelia-de-lange-syndrome-a-case-from-democratic-republic-of-the-congo
#9
Tony Kayembe Kitenge, Toni Kasole Lubala, Sebastien Mbuyi-Musanzayi, Leon Kabamba Ngombe, Cyrille Katshiez Nawej, Paul Musa Obadia, Celestin Banza Lubaba Nkulu, Benoit Nemery, Koenraad Devriendt
No abstract text is available yet for this article.
October 2016: Clinical Dysmorphology
https://www.readbyqxmd.com/read/27085497/short-term-health-effects-in-the-general-population-following-a-major-train-accident-with-acrylonitrile-in-belgium
#10
K Simons, T De Smedt, C Stove, P De Paepe, M Bader, B Nemery, C Vleminckx, K De Cremer, I Van Overmeire, S Fierens, B Mertens, T Göen, T Schettgen, H Van Oyen, J Van Loco, A Van Nieuwenhuyse
BACKGROUND: Following a train derailment, several tons of acrylonitrile (ACN) exploded, inflamed and part of the ACN ended up in the sewage system of the village of Wetteren. More than 2000 residents living in the close vicinity of the accident and along the sewage system were evacuated. A human biomonitoring study of the adduct N-2-cyanoethylvaline (CEV) was carried out days 14-21 after the accident. OBJECTIVES: (1) To describe the short-term health effects that were reported by the evacuated residents following the train accident, and (2) to explore the association between the CEV concentrations, extrapolated at the time of the accident, and the self-reported short-term health effects...
July 2016: Environmental Research
https://www.readbyqxmd.com/read/27044488/preeclampsia-and-toxic-metals-a-case-control-study-in-kinshasa-dr-congo
#11
Jean-Pierre Elongi Moyene, Hans Scheers, Barthélémy Tandu-Umba, Vincent Haufroid, Baudouin Buassa-Bu-Tsumbu, Fons Verdonck, Bernard Spitz, Benoit Nemery
BACKGROUND: Preeclampsia is frequent in Kinshasa (Democratic Republic of Congo), especially during the dry season. We tested whether preeclampsia was associated with exposure to environmental metals. METHODS: Using a case-control design, 88 women hospitalized with preeclampsia (cases) and 88 healthy pregnant women from the antenatal clinic (controls) were included in the study; 67 and 109 women were enrolled during the rainy and dry season, respectively. The concentrations of 24 elements were quantified by inductively coupled plasma mass spectrometry (ICP-MS) in 24-h urine collections...
2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/26803678/a-cross-sectional-study-with-an-improved-methodology-to-assess-occupational-air-pollution-exposure-and-respiratory-health-in-motorcycle-taxi-driving
#12
Herve Lawin, Gildas Agodokpessi, Paul Ayelo, Jacqueline Kagima, Rodrigue Sonoukon, Bertrand H Mbatchou Ngahane, Olayemi Awopeju, William M Vollmer, Benoit Nemery, Peter Burney, Benjamin Fayomi
INTRODUCTION: Motorcycle taxi driving is common in many African cities. This study tested whether this occupation is associated with more respiratory disorders in a context of widespread urban air pollution with an improved methodology. METHODS: In a cross sectional study we compared 85 male motorcycle taxi drivers in the capital city of the Republic of Benin (Cotonou) with an age and neighborhood matched control group. All participants carried a portable carbon monoxide data logger for 8 hours per day to assess exposure to air pollution...
April 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/26725468/sleep-disturbances-and-neurotoxicity-in-workers-exposed-to-hydrocarbons-an-observational-study-from-algeria
#13
Samira Sekkal, Lidia Casas, Nahida Haddam, Linda Bouhacina, Hans Scheers, Abdesselam Taleb, Benoit Nemery
BACKGROUND: Occupational exposure to solvents may lead to neurotoxicity and sleep disturbances. We aimed to investigate the association of occupational exposure to petroleum-derived hydrocarbons with neurotoxicity and sleep disturbance symptoms. METHODS: We included male workers handling/distributing petroleum products (exposed, n = 250) and electricians (non-exposed, n = 250) from two companies in Tlemcen (Algeria). Neurotoxicity was evaluated with the Q-16 questionnaire, and sleep disturbances with the Epworth and the Berlin questionnaires...
February 2016: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/26468151/toluene-diisocyanate-and-methylene-diphenyl-diisocyanate-asthmatic-response-and-cross-reactivity-in-a-mouse-model
#14
Lore Pollaris, Fien Devos, Vanessa De Vooght, Sven Seys, Benoit Nemery, Peter H M Hoet, Jeroen A J Vanoirbeek
Both 2,4-toluene diisocyanate (TDI) and 4,4-methylene diphenyl diisocyanate (MDI) can cause occupational asthma. In this study, we optimized our mouse model of chemical-induced asthma in the C57Bl/6 mice strain using the model agent TDI. Furthermore, we validated MDI in this mouse model and investigated whether cross-reactivity between TDI and MDI is present. On days 1 and 8, C57Bl/6 mice were dermally treated (20 µl/ear) with 3 % MDI, 2 % TDI or the vehicle acetone olive oil (AOO) (3:2). On day 15, they received a single oropharyngeal challenge with 0...
July 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/26463695/long-term-exposure-to-particulate-matter-air-pollution-is-a-risk-factor-for-stroke-meta-analytical-evidence
#15
Hans Scheers, Lotte Jacobs, Lidia Casas, Benoit Nemery, Tim S Nawrot
BACKGROUND AND PURPOSE: Epidemiological studies suggest an association between stroke incidence and stroke mortality and long-term exposure to particulate matter (PM) air pollution. However, the magnitude of the association is still unclear. METHODS: We searched the Pubmed citation database for epidemiological studies and reviews on stroke and PM exposure. Then, we carried out a meta-analysis to quantify the pooled association between stroke incidence and mortality and long-term exposure to PM...
November 2015: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/26398101/proteomic-alterations-in-b-lymphocytes-of-sensitized-mice-in-a-model-of-chemical-induced-asthma
#16
Steven Haenen, Jeroen A J Vanoirbeek, Vanessa De Vooght, Liliane Schoofs, Benoit Nemery, Elke Clynen, Peter H M Hoet
INTRODUCTION AND AIM: The role of B-lymphocytes in chemical-induced asthma is largely unknown. Recent work demonstrated that transferring B lymphocytes from toluene diisocyanate (TDI)-sensitized mice into naïve mice, B cell KO mice and SCID mice, triggered an asthma-like response in these mice after a subsequent TDI-challenge. We applied two-dimensional difference gel electrophoresis (2D-DIGE) to describe the "sensitized signature" of B lymphocytes comparing TDI-sensitized mice with control mice...
2015: PloS One
https://www.readbyqxmd.com/read/26056995/fetal-growth-and-maternal-exposure-to-particulate-air-pollution-more-marked-effects-at-lower-exposure-and-modification-by-gestational-duration
#17
Ellen Winckelmans, Bianca Cox, Evelyne Martens, Frans Fierens, Benoit Nemery, Tim S Nawrot
While there is growing evidence that air pollution reduces fetal growth, results are inconclusive with respect to the gestational window of effect. We investigated maternal exposure to particulate matter (PM10) in association with birth weight and fetus growth with a focus on the shape of the association and gestational age at birth as a potential effect modifier. The study population consisted of 525,635 singleton live births in Flanders (Belgium) between 1999 and 2009. PM10 exposure at maternal residence was averaged over various time windows...
July 2015: Environmental Research
https://www.readbyqxmd.com/read/25940953/proximity-to-blue-spaces-and-risk-of-infection-with-pseudomonas-aeruginosa-in-cystic-fibrosis-a-case-control-analysis
#18
Pieter C Goeminne, Tim S Nawrot, Kris De Boeck, Ben Nemery, Lieven J Dupont
BACKGROUND: The acquisition of Pseudomonas aeruginosa in cystic fibrosis (CF) is associated with lower survival, decreased lung function, worse radiological scores, increased exacerbations and reduced nutritional status. Open water is a known reservoir and a potential source of exposure to P. aeruginosa. METHODS: Twenty eight adult CF patients who had no history of P. aeruginosa and had negative P. aeruginosa IgG antibody levels, were matched by age and sex with 28 CF patients with chronic P...
November 2015: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/25907379/methylisothiazolinone-dermal-and-respiratory-immune-responses-in-mice
#19
Fien C Devos, Lore Pollaris, Sofie Van Den Broucke, Sven Seys, An Goossens, Benoit Nemery, Peter H M Hoet, Jeroen A J Vanoirbeek
Methylisothiazolinone (MI), a widely used chemical preservative in industrial and household products, and cosmetics, has been associated with allergic contact dermatitis. However, the asthmogenic capacity of MI is currently unknown. In this study, we investigated the capacity of MI to elicit asthma-like responses in a validated mouse model. On days 1 and 8, mice (C57Bl/6 and BALB/c) were dermally treated with MI or vehicle on each ear. On day 15, mice received a single intranasal challenge with MI or vehicle...
June 15, 2015: Toxicology Letters
https://www.readbyqxmd.com/read/25904399/mechanoreceptors-in-the-anterior-horn-of-the-equine-medial-meniscus-an-immunohistochemical-approach
#20
E Nemery, A Gabriel, S Grulke, J Piret, V Toppets, N Antoine
Lameness due to stifle and especially meniscal lesions is frequent in equine species. In humans, mechanoreceptors involved in proprioceptive function are well studied. Given the high incidence of meniscal injuries in horses, and the lack of information concerning them in equine menisci, our objective was to study these corpuscles in six healthy anterior horns of the equine medial meniscus, which is the most common localisation reported for equine meniscal injuries. Immunohistochemical stainings were performed using antibodies against high molecular weight neurofilaments and glial fibrillary acidic proteins...
April 2016: Anatomia, Histologia, Embryologia
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