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https://www.readbyqxmd.com/read/27914866/co-signaling-molecules-in-maternal-fetal-immunity
#1
REVIEW
Yuan-Yuan Xu, Song-Cun Wang, Da-Jin Li, Mei-Rong Du
Physiologically, a successful pregnancy requires the maternal immune system to recognize and tolerate the semiallogeneic fetus, and allow for normal invasion of trophoblasts. Thus, pregnancy complications are considered to be associated with dysfunctional maternal-fetal crosstalk. Co-signaling molecules are a group of cell surface molecules that positively or negatively modulate the immune response. Well studied in the fields of oncology and transplantation, they are also suggested to be involved in maternal-fetal crosstalk...
November 30, 2016: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/27912953/evaluating-the-effect-of-matricaria-recutita-and-mentha-piperita-herbal-mouthwash-on-management-of-oral-mucositis-in-patients-undergoing-hematopoietic-stem-cell-transplantation-a-randomized-double-blind-placebo-controlled-clinical-trial
#2
Maria Tavakoli Ardakani, Sara Ghassemi, Mahshid Mehdizadeh, Faraz Mojab, Jamshid Salamzadeh, Samaneh Ghassemi, Abbas Hajifathali
OBJECTIVES: To investigate the effects of Matricaria recutita and Mentha piperita on oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT). DESIGN: Randomized double blind placebo controlled clinical trial. SETTING: Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, and Bone Marrow Transplantation Center at Taleghani Teaching Hospital, Tehran, Iran. PARTICIPANTS: Sixty patients undergoing HSCT were randomly assigned to two groups: placebo (n=33), and herbal mouthwash group (n=27)...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27909363/evidence-of-reliability-validity-and-practicality-for-the-canadian-physiotherapy-assessment-of-clinical-performance
#3
Brenda Mori, Kathleen E Norman, Dina Brooks, Jodi Herold, Dorcas E Beaton
Purpose: To investigate the internal consistency, construct validity, and practicality of the Canadian Physiotherapy Assessment of Clinical Performance (ACP), a descriptive measure used by physiotherapy students and their clinical instructors (CIs) at the mid- and endpoints of an internship to describe the students' behaviours as observed in the clinical education setting relative to what might be expected of an entry-level physiotherapist. Methods: This multi-centre study piloted the ACP in 10 university physiotherapy (PT) programmes...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27909165/psilocybin-produces-substantial-and-sustained-decreases-in-depression-and-anxiety-in-patients-with-life-threatening-cancer-a-randomized-double-blind-trial
#4
Roland R Griffiths, Matthew W Johnson, Michael A Carducci, Annie Umbricht, William A Richards, Brian D Richards, Mary P Cosimano, Margaret A Klinedinst
: Cancer patients often develop chronic, clinically significant symptoms of depression and anxiety. Previous studies suggest that psilocybin may decrease depression and anxiety in cancer patients. The effects of psilocybin were studied in 51 cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety. This randomized, double-blind, cross-over trial investigated the effects of a very low (placebo-like) dose (1 or 3 mg/70 kg) vs. a high dose (22 or 30 mg/70 kg) of psilocybin administered in counterbalanced sequence with 5 weeks between sessions and a 6-month follow-up...
December 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27909084/sustained-benefits-of-exercise-based-motivational-interviewing-but-only-among-nonusers-of-opioids-in-patients-with-fibromyalgia
#5
Sunghye Kim, James E Slaven, Dennis C Ang
OBJECTIVE: Given the known side effects of opioids and their potential effects on cognition, we sought to evaluate the benefits of motivational interviewing (MI) to promote physical activity on 2 subsets of participants with fibromyalgia (FM): nonusers and users of opioids. METHODS: This was a secondary data analysis of a 36-week randomized controlled trial to assess the efficacy of MI to promote physical activity among participants with FM. Participants were randomized to 1 of 2 treatment arms: 6 phone-based MI sessions (n = 107) or 6 sessions of FM self-management instructions [attention control (AC), n = 109]...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27905957/factors-associated-with-no-shows-and-rescheduling-mri-appointments
#6
Majeed O AlRowaili, Anwar E Ahmed, Hasan A Areabi
BACKGROUND: One of the major challenges facing global radiology services comes from delays connected to long waiting lists for magnetic resonance imaging (MRI) procedures. Such delays in diagnostic procedures could lead to poorer patient care outcomes. This study intended to estimate the rate of "No-Shows" or "Reschedule" MRI appointments. We also investigated the factors correlating No-Shows and Reschedule MRI appointments. METHODS: A cross-sectional study was conducted in Saudi Arabia using data obtained via MRI schedule reviews and self-administrated questionnaires...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27905641/-factors-associated-with-success-of-a-smoking-cessation-program
#7
Pedro Peña, Mónica Zagolin, Mónica Acuña, Sandra Navarrete, Pilar Bustamante, Andrea Canals
BACKGROUND: Smoking cessation therapies include counseling, psychological management and pharmacological therapy. Varenicline is the most effective and safe medication available. AIM: To study risk factors for the failure of pharmacological smoking cessation therapy with varenicline. PATIENTS AND METHODS: Retrospective analysis of 281 patients aged 45 ± 11 years (65% males) with a mean consumption of 31 ± 22 packs/year. They completed a smoking cessation program comprising psychological support and use of varenicline in a private clinic...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27904986/a-qualitative-study-of-clinicians-experience-with-rating-of-the-global-assessment-of-functioning-gaf-scale
#8
I H Monrad Aas, Ove Sonesson, Steffen Torp
The severity of illness in psychiatry is rated using the Global Assessment of Functioning (GAF) scale. The GAF scale is often used in both research settings and in the clinic. The scale ranges from 1 to 100 and is subdivided into ten 10-point intervals, each with verbal rating instructions called anchor points and examples. GAF is an instrument that needs improvement. Studying clinicians' experiences with this rating system may be important for developing improvements. The aim of this study was to collect information from clinicians about their experiences with the GAF instrument, and to collect their ideas on how the GAF scale can be improved, particularly in the area of verbal instructions (i...
November 30, 2016: Community Mental Health Journal
https://www.readbyqxmd.com/read/27904273/efficacy-and-safety-of-cream-containing-climbazole-piroctone-olamine-for-facial-seborrheic-dermatitis-a-single-center-open-label-split-face-clinical-study
#9
Hae Jeong Youn, Soo Young Kim, Minji Park, Won Hee Jung, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn
BACKGROUND: Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. OBJECTIVE: We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms. METHODS: We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27900995/smartphone-application-wechat-for-clinical-follow-up-of-discharged-patients-with-head-and-neck-tumors-a-randomized-controlled-trial
#10
Ke-Xing Lyu, Jing Zhao, Bin Wang, Guan-Xia Xiong, Wei-Qiang Yang, Qi-Hong Liu, Xiao-Lin Zhu, Wei Sun, Ai-Yun Jiang, Wei-Ping Wen, Wen-Bin Lei
BACKGROUND: Nowadays, social media tools such as short message service, Twitter, video, and web-based systems are more and more used in clinical follow-up, making clinical follow-up much more time- and cost-effective than ever before. However, as the most popular social media in China, little is known about the utility of smartphone WeChat application in follow-up. In this study, we aimed to investigate the feasibility and superiority of WeChat application in clinical follow-up. METHODS: A total of 108 patients diagnosed with head and neck tumor were randomized to WeChat follow-up (WFU) group or telephone follow-up (TFU) group for 6-month follow-up...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27900615/good-manufacturing-practice-requirements-for-the-production-of-tissue-vitrification-and-warming-and-recovery-kits-for-clinical-research
#11
Monica M Laronda, Kelly E McKinnon, Alison Y Ting, Ann V Le Fever, Mary B Zelinski, Teresa K Woodruff
Products that are manufactured for use in a clinical trial, with the intent of gaining US Food and Drug Administration (FDA) approval for clinical use, must be produced under an FDA approved investigational new drug (IND) application. We describe work done toward generating reliable methodology and materials for preserving ovarian cortical tissue through a vitrification kit and reviving this tissue through a warming and recovery kit. We have described the critical steps, procedures, and environments for manufacturing products with the intent of submitting an IND...
November 30, 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27900185/benefits-of-a-novel-concept-of-home-based-exercise-with-the-aim-of-preventing-aspiration-pneumonia-and-falls-in-frail-older-women-a-pragmatic-controlled-trial
#12
Katsuhiko Takatori, Daisuke Matsumoto, Munenori Nishida, Shinnichiro Matsushita, Tatsuya Noda, Tomoaki Imamura
AIM: To investigate whether home-based exercise with the aim of preventing aspiration pneumonia and accidental falls improves swallowing-related and physical functions in community-dwelling frail older women. METHODS: Participants were 266 community-dwelling frail older women in a long-term care prevention class (mean (SD): age 75 (5) years). Participants were allocated to either an intervention group or a control group. In the intervention group, participants were asked to perform, at least three times a week for 6 months, a home-based exercise programme that was specifically developed to prevent aspiration pneumonia and accidental falls...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27898165/sinus-augmentation-and-simultaneous-implant-placement-success-pilot-study-2008-2011
#13
Melissa Tormos, Jose Morales, Natalia Guevara, Augusto R Elías, Lydia López, Omar García
OBJECTIVE: 1) To describe implant success in the posterior maxillary when a sinus augmentation procedure was performed simultaneously with implant placement and then compare differences in success when sinus augmentation was delayed in patients attending the maxillofacial surgery clinic of the University of Puerto Rico, 2008 through 2011. 2) To determine sociodemographic characteristics, ASA classification, graft material, and final restoration and, using a questionnaire, determine as well patient satisfaction...
December 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27896914/an-innovative-textbook-design-and-implementation
#14
Rafael Ortega, Vafa Akhtar-Khavari, Paul Barash, Sam Sharar, M Christine Stock
BACKGROUND: The 'flipped classroom' instructional strategy has gained much momentum in educational discourse, yet no single educational offering exists in postgraduate medical education (PME) to systematically replace the lecture element of didactic sessions. This article describes the design and implementation of Clinical Anesthesia Fundamentals, the first known textbook in PME addressing this gap in resources through the integration of full-length interactive multimedia-enhanced video lectures...
November 29, 2016: Clinical Teacher
https://www.readbyqxmd.com/read/27896210/comparison-of-the-bonding-strengths-of-second-and-third-generation-light-emitting-diode-light-curing-units
#15
Hee-Min Lee, Sang-Cheol Kim, Kyung-Hwa Kang, Na-Young Chang
OBJECTIVE: With the introduction of third-generation light-emitting diodes (LEDs) in dental practice, it is necessary to compare their bracket-bonding effects, safety, and efficacy with those of the second-generation units. METHODS: In this study, 80 extracted human premolars were randomly divided into eight groups of 10 samples each. Metal or polycrystalline ceramic brackets were bonded on the teeth using second- or third-generation LED light-curing units (LCUs), according to the manufacturers' instructions...
November 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27891570/pragmatic-approach-to-manage-new-oral-anticoagulants-in-patients-undergoing-dental-extractions-a-prospective-case-control-study
#16
Isabel Miclotte, Maarten Vanhaverbeke, Jimoh Olubanwo Agbaje, Paul Legrand, Thomas Vanassche, Peter Verhamme, Constantinus Politis
OBJECTIVES: The aim of this study was to validate a standardized pragmatic approach to manage new oral anticoagulants (NOACs) in patients who undergo dental extractions. MATERIALS AND METHODS: This prospective case-control study in patients undergoing dental extraction included 26 patients (mean age 76 years, 57% male) treated with dabigatran, rivaroxaban, or apixaban and 26 matched controls. Regardless of timing of extraction, drug regimen, or renal function, patients were instructed to skip only the dose on the morning of the procedure...
November 28, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27891454/efficacy-and-safety-of-intralesional-xantinol-nicotinate-in-the-treatment-of-various-stages-of-oral-submucous-fibrosis
#17
Udita Singh
INTRODUCTION: Oral Submucous Fibrosis (OSMF) is one of the most prevalent potentially malignant disorders seen in South east population since ages. Despite the extensive amount of research held in this field, its treatment still remains a challenge. In this study, we present our experience in successfully managing OSMF with intralesional injections of a peripheral vasodilator namely xantinol nicotinate. AIM: To determine the efficacy and safety of intralesional xantinol nicotinate in the treatment of various stages of OSMF...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890870/improving-the-quality-of-postgraduate-education-in-traditional-japanese-kampo-medicine-for-junior-residents-an-exploratory-survey-conducted-in-five-institutions-in-the-tohoku-area
#18
Shin Takayama, Seiichi Kobayashi, Soichiro Kaneko, Masao Tabata, Shinya Sato, Keiichi Ishikawa, Saya Suzuki, Ryutaro Arita, Natsumi Saito, Tetsuharu Kamiya, Hitoshi Nishikawa, Yuka Ikeno, Junichi Tanaka, Minoru Ohsawa, Akiko Kikuchi, Takehiro Numata, Hitoshi Kuroda, Michiaki Abe, Satoru Ishibashi, Nobuo Yaegashi, Tadashi Ishii
Traditional Japanese (Kampo) medicine has been widely applied in general medicine in Japan. In 2001, the model core curriculum for Japanese medical education was revised to include Kampo medicine. Since 2007, all 80 Japanese medical schools have incorporated it within their programs. However, postgraduate training or instruction of Kampo medicine has not been recognized as a goal for the clinical training of junior residents by Japan's Ministry of Health, Labour and Welfare; little is known about postgraduate Kampo medicine education...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27888946/difficult-doctors-difficult-patients-building-empathy
#19
Patricia F Anderson, Elise Wescom, Ruth C Carlos
Effective doctor-patient communication facilitates the therapeutic relationship, promotes patient physical and mental health, and improves physician satisfaction. Methods of teaching effective communication use a range of techniques, typically combining didactic instruction with simulated communication encounters and reflective discussion. Rarely are patients and physicians exposed to these instructions as colearners. The evidence for the utility of graphic stories, comics, and cartoons to improve patient comprehension and self-regulation is small but encouraging...
December 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27888749/young-people-with-higher-social-anxiety-are-less-likely-to-adopt-the-perspective-of-another-data-from-the-director-task
#20
Victoria Pile, Simone P W Haller, Chii Fen Hiu, Jennifer Y F Lau
BACKGROUND AND OBJECTIVES: Young people with social anxiety display poor social functioning but it is unclear whether this is underscored by difficulties in key social cognitive abilities, such as perspective taking. Here, we examined whether increased social anxiety is associated with reduced accuracy on a perspective taking task and whether this relationship is stronger at particular periods within adolescence. METHODS: Fifty-nine adolescents aged 11-19 years completed the computerised Director Task (DT) and the Social Anxiety Scale for Adolescence...
November 5, 2016: Journal of Behavior Therapy and Experimental Psychiatry
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