keyword
https://read.qxmd.com/read/38479252/non-pharmacological-and-pharmacological-treatments-for-bone-health-after-stroke-systematic-review-with-meta-analysis
#21
REVIEW
Huixi Ouyang, Tsun C Lee, Faye Yf Chan, Xun Li, King Y Lai, Wing Y Lam, Tsz Y Yung, Marco Y C Pang
BACKGROUND: Hemi-osteoporosis is a common secondary complication of stroke. No systematic reviews of pharmacological and non-pharmacological agents for post-stroke bone health have estimated the magnitude and precision of effect sizes to guide better clinical practice. OBJECTIVES: To examine the benefits and harms of pharmacological and non-pharmacological agents on bone health in post-stroke individuals. METHODS: Eight databases were searched (PubMed, Cochrane library, Scopus, CINAHL Complete, Embase, PEDro, Clinicaltrils...
March 12, 2024: Annals of Physical and Rehabilitation Medicine
https://read.qxmd.com/read/38477794/defining-the-key-clinician-skills-and-attributes-for-competency-in-managing-patients-with-osteoporosis-and-fragility-fractures
#22
JOURNAL ARTICLE
Lesley E Jackson, Kenneth G Saag, Sindhu R Johnson, Maria I Danila
Osteoporosis and fragility fractures are managed by clinicians across many medical specialties. The key competencies of clinicians delivering bone health care have not been systematically established. We aimed to develop a decision rule to define the threshold of adequate skills and attributes associated with clinical competency in bone health for a clinician serving as a referral source for bone health care. Using a modified-Delphi method, we invited clinicians with expertise in treating osteoporosis and representatives of patient advocacy groups focused on bone health to create a list of desirable characteristics of a clinician with bone health competency...
February 2, 2024: Journal of Bone and Mineral Research
https://read.qxmd.com/read/38466062/effectiveness-of-mobile-health-platform-based-continuity-of-care-in-osteoporosis-prevention-and-treatment
#23
JOURNAL ARTICLE
Wei-Ping Cheng, Li Sun, Dan Shen, Guan-Hua Xu, Jia-Wei Jiang, Hai-Yan Gu
OBJECTIVE: To assess the effectiveness of using mobile health platforms for continuous care in preventing and treating osteoporosis. METHODS: 114 patients with osteoporosis admitted to Nantong First People's Hospital from March 2021 to June 2022 were recruited and assigned equally via random number table method to receive either routine care (namely education on osteoporosis disease, dietary guidance, exercise guidance, activity guidance, medication supervision, fall prevention, psychological care, and secondary health education at the time of discharge) (routine group) or mobile health platform-based continuity of care (continuity group), with 57 patients in each group...
March 8, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38397722/enhancing-behavioural-changes-a-narrative-review-on-the-effectiveness-of-a-multifactorial-app-based-intervention-integrating-physical-activity
#24
REVIEW
Giulia Di Martino, Carlo Della Valle, Marco Centorbi, Andrea Buonsenso, Giovanni Fiorilli, Giuseppe Calcagno, Enzo Iuliano, Alessandra di Cagno
The rapid evolution of technologies is a key innovation in the organisation and management of physical activities (PA) and sports. The increase in benefits and opportunities related to the adoption of technologies for both the promotion of a healthy lifestyle and the management of chronic diseases is evident. In the field of telehealth, these devices provide personalised recommendations, workout monitoring and injury prevention. The study aimed to provide an overview of the landscape of technology application to PA organised to promote active lifestyles and improve chronic disease management...
February 16, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38396142/bone-health-in-women-with-premature-ovarian-insufficiency-early-menopause-a-23-year-longitudinal-analysis
#25
JOURNAL ARTICLE
A R Jones, J Enticott, P R Ebeling, G D Mishra, H T Teede, A J Vincent
STUDY QUESTION: What is the frequency of, and predictors for, osteoporosis, fractures, and osteoporosis management (investigation, treatment) in women with premature ovarian insufficiency (POI; menopause <40 years) and early menopause (EM; menopause 40-44years)? SUMMARY ANSWER: Over the 23-year follow-up duration, at a mean age of 68 years, women with POI/EM had higher osteoporosis/fracture risk and prevalence, higher osteoporosis screening and anti-osteoporosis medication use compared to women with usual age menopause; increasing age was predictive of increased risk of osteoporosis/fracture and menopause hormone therapy (MHT) prior to or at study entry (aged 45-50 years) was protective...
February 23, 2024: Human Reproduction
https://read.qxmd.com/read/38386243/wnt-notch-signaling-and-exercise-what-are-their-functions
#26
REVIEW
Yijie Zhao, Guangjun Wang, Zhifeng Wei, Duo Li, Mohammadamin Morshedi
In the last decade, the study of Wnt and Notch signaling in cell biology has led to significant progress in understanding embryogenesis, bone development, muscle healing, neurogenesis, and tumorigenesis. It has been found that regular physical activity can counteract the decline of skeletal muscle caused by aging, which is linked to osteoporosis, regenerative neurogenesis, hippocampal function, cognitive ability, and the creation of neuromuscular junctions. Despite these discoveries, there is still uncertainty about how cell biology and exercise can impact the Wnt and Notch signaling pathways in the locomotor system...
February 22, 2024: Human Cell
https://read.qxmd.com/read/38375684/limited-improvement-with-minimally-invasive-lumbar-decompression-alone-for-degenerative-scoliosis-with-cobb-angle-over-20-degrees-the-impact-of-decompression-location
#27
JOURNAL ARTICLE
Tomoyuki Asada, Chad Z Simon, Nishtha Singh, Olivia Tuma, Tejas Subramanian, Kasra Araghi, Amy Z Lu, Eric Mai, Yeo Eun Kim, Myles R J Allen, Maximilian Korsun, Joshua Zhang, Cole Kwas, Sumedha Singh, James Dowdell, Evan D Sheha, Sheeraz A Qureshi, Sravisht Iyer
STUDY DESIGN: Retrospective review of a prospectively collected multi-surgeon registry. OBJECTIVE: To evaluate the outcomes of minimally invasive (MI) decompression in patients with severe degenerative scoliosis (DS) and identify factors associated with poorer outcomes. SUMMARY OF BACKGROUND CONTEXT: MI decompression has gained widespread acceptance as a treatment option for patients with lumbar canal stenosis and DS. However, there is a lack of research regarding the clinical outcomes and the impact of MI decompression location in patients with severe DS exhibiting a Cobb angle exceeding 20 degrees...
February 20, 2024: Spine
https://read.qxmd.com/read/38368307/twelve-month-resistance-and-impact-exercise-program-or-risedronate-provides-a-relative-benefit-to-hip-bone-structure-in-postmenopausal-women-results-from-a-randomized-controlled-trial
#28
JOURNAL ARTICLE
R Blay, L E Flores, K Kupzyk, N Waltman, J Lappe, L Mack, L Bilek
UNLABELLED: Bone strength estimates are important for fracture prevention. This study compared bone strength changes in postmenopausal women with low bone mass who were assigned to 12 months of exercise, a bone medication, or control. Exercise and bone medications benefited structure at the hip. Structure should be considered in fracture prevention research. PURPOSE: Exercise and bisphosphonates reduce fracture risk, but their impact on estimates of bone strength remains uncertain...
February 17, 2024: Osteoporosis International
https://read.qxmd.com/read/38358001/mechanical-strain-regulates-osteogenesis-via-antxr1-lncrna-h19-wnt-%C3%AE-catenin-axis
#29
JOURNAL ARTICLE
Lifei Liu, Jianmin Guo, Xiaoyang Tong, Miao Zhang, Xi Chen, Mei Huang, Chenyu Zhu, Samuel Bennett, Jiake Xu, Jun Zou
Alleviating bone loss is an essential way to prevent osteoporotic fractures. Proper exercise improves bone density without the side effects of long-term medications, but the mechanism is unclear. Our study explored the role of Antxr1/LncRNA H19/Wnt/β-catenin axis in the process of exercise-mediated alleviation of bone loss. Here we discovered that moderate-intensity treadmill exercise alleviates bone loss caused by ovariectomy and ameliorates bone strength accompanied by an increased lncRNA H19 expression...
February 15, 2024: Journal of Cellular Physiology
https://read.qxmd.com/read/38344943/development-of-an-exercise-therapy-referral-clinical-support-tool-for-patients-with-osteoporosis-at-risk-for-falls
#30
JOURNAL ARTICLE
Garrett S Bullock, Pamela Duncan, Alison M Chandler, Aylin A Aguilar, Nancy Latham, Tom Storer, Neil Alexander, Christine M McDonough
BACKGROUND: The purpose of this study was to develop a clinical support tool for osteoporosis clinic providers to support risk assessment and referrals for evidence-based exercise therapy programs. METHODS: A sequential Delphi method was used with a multidisciplinary group of national falls experts, to provide consensus on referral to exercise therapy for patients at risk for falls. The Delphi study included a primary research team, expert panel, and clinical partners to answer the questions: (1) "What patient characteristics are needed to develop a clinical support tool?"; (2) "What are the recommended exercise referrals for patients with osteoporosis at risk for falls?" The consensus process consisted of two rounds with 8 weeks between meetings...
February 12, 2024: Journal of the American Geriatrics Society
https://read.qxmd.com/read/38342790/the-relationship-among-probable-sarcopenia-osteoporosis-and-supraspinatus-tendon-tears-in-postmenopausal-women-the-sarcosp-study
#31
JOURNAL ARTICLE
Murat Kara, Özgür Kara, Mahmut Esad Durmuş, Pelin Analay, Fatıma Edibe Şener, Beyza Nur Çıtır, Gizem Olgu Korkmaz, Zeliha Ünlü, Tülay Tiftik, Eda Gürçay, Cevriye Mülkoğlu, Berkay Yalçınkaya, Fatih Bağcıer, Mahmud Fazıl Aksakal, Kübra Erdoğan, Ahmet Sertçelik, Banu Çakır, Bayram Kaymak, Levent Özçakar
We aimed to investigate the relationship among probable sarcopenia, osteoporosis (OP) and supraspinatus tendon (SSP) tears in postmenopausal women. Postmenopausal women screened/followed for OP were recruited. Demographic data, comorbidities, exercise/smoking status, and handgrip strength values were recorded. Probable sarcopenia was diagnosed as handgrip strength values < 20 kg. Achilles and SSP thicknesses were measured using ultrasound. Among 1443 postmenopausal women, 268 (18.6%) subjects had SSP tears...
February 12, 2024: Calcified Tissue International
https://read.qxmd.com/read/38318334/assessment-of-osteoporosis-knowledge-and-its-determinants-among-tuberculosis-patients-in-tertiary-care-hospital-malaysia-a-prospective-study
#32
JOURNAL ARTICLE
Zohra Bhatti, Madeeha Laghari, Amer Hayat Khan, Bandeh Ali Talpur, Syed Azhar Syed Sulaiman
OBJECTIVE: Osteoporosis self-care knowledge is essential to encourage the patient's contribution towards controlling the disease. Osteoporosis incidence with various infectious diseases prompts us to conduct a study on osteoporosis knowledge among Tuberculosis (TB) patients. This study aimed to assess osteoporosis-related knowledge and its influencing factors among TB patients. METHODS: A prospective cross-sectional study was conducted in the TB clinic of Hospital Pulau Pinang, Malaysia, and an osteoporosis knowledge test (OKT), a structured questionnaire, was used to collect data...
February 2024: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
https://read.qxmd.com/read/38306807/cafeteria-diet-can-affect-bone-microarchitecture-in-sedentary-and-trained-male-rats
#33
JOURNAL ARTICLE
Marcio Koiti Saito, Beatriz Kawano de Oliveira, Ana Paula Macedo, Caio Sorrentino Dos Santos, Ricardo Tadeu Lopes, Jéssica Suzuki Yamanaka, Antonio Carlos Shimano
INTRODUCTION: Poor eating habits and a sedentary lifestyle can impair health. Regular physical activity improves the quality of life and is essential for bone health. Therefore, the present study aimed to evaluate the effects of the cafeteria diet on bone quality of sedentary and exercised rats. METHODS: Sixty young male Wistar rats were divided into six groups (n=10) according to diet composition and activity level, being: SD+CON, standard diet and control; SD+SED, standard diet and sedentary; SD+EX, standard diet and exercised; CD+CON, cafeteria diet and control; CD+SED, cafeteria diet and sedentary; CD+EX, cafeteria diet and exercised...
January 24, 2024: Journal of Clinical Densitometry
https://read.qxmd.com/read/38305399/narrative-review-of-traditional-chinese-medicine-in-the-treatment-of-postmenopausal-osteoporosis
#34
JOURNAL ARTICLE
Li Qi, Wang Wei-Guo, Huang Xu-Dong, Zhao Xiu-Mei, X U Xiao-Dong, Zhang Cheng-Ming
An increasing percentage of people in China are suffering from osteoporosis, particularly postmenopausal osteoporosis (PMOP), as the country rapidly evolves into an aging culture. Patients with osteoporosis are inclined to endure fractures, as well as deformities and impairments, which drastically decrease people's quality of life. The benefits of traditional Chinese medicine (TCM) treatment have continued to become increasingly apparent as reports of adverse responses to Western medications increased. The main advantage of traditional Chinese medicine treatment is that pharmacological interactions may be employed to lessen adverse effects while increasing therapeutic efficacy...
January 17, 2024: Combinatorial Chemistry & High Throughput Screening
https://read.qxmd.com/read/38287664/association-between-osteoporosis-and-skeletal-muscle-mass-in-men
#35
JOURNAL ARTICLE
Masaya Mizutani, Yawara Eguchi, Toru Toyoguchi, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Satoshi Maki, Junichi Nakamura, Shigeo Hagiwara, Yasuchika Aoki, Masahiro Inoue, Masao Koda, Hiroshi Takahashi, Tsutomu Akazawa, Seiji Ohtori
STUDY DESIGN: Cross-sectional study. PURPOSE: This cross-sectional study aimed to investigate the risk factors for osteoporosis in men by assessing bone mineral density (BMD), skeletal muscle mass, body fat mass, grip strength, and advanced glycation end products (AGEs). OVERVIEW OF LITERATURE: Fewer studies have reported the correlation between BMD and skeletal muscle mass in women. Moreover, a few studies have examined the relationship between osteoporosis and skeletal muscle mass...
February 2024: Asian Spine Journal
https://read.qxmd.com/read/38229012/effects-of-resistance-training-and-nutritional-support-on-osteosarcopenia-in-older-community-dwelling-postmenopausal-korean-females-erto-k-study-a-study-protocol
#36
JOURNAL ARTICLE
Byung Chan Lee, Kyung Il Kim, Kang Hee Cho, Chang-Won Moon
BACKGROUND: Osteosarcopenia is geriatric syndrome defined as the concomitant occurrence of osteopenia/osteoporosis, and sarcopenia. Osteosarcopenia is a relatively new concept in geriatric medicine; however, it may increase the risk of fragility fractures, several morbidities and mortalities, and socioeconomic costs. Although resistance exercises and nutritional support-including protein, calcium, and vitamin D-are potential non-pharmacological management procedures, evidence is still lacking...
January 17, 2024: BMC Geriatrics
https://read.qxmd.com/read/38218331/the-role-of-irisin-in-kidney-diseases
#37
REVIEW
Xiejia Li, Bengt Lindholm
Irisin is a hormone that is produced mainly by skeletal muscles in response to exercise. It has been found to have a close correlation with obesity and diabetes mellitus for its energy expenditure and metabolic properties. Recent research has revealed that irisin also possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, which make it associated with major chronic diseases, such as chronic kidney disease (CKD), liver diseases, osteoporosis, atherosclerosis and Alzheimer s disease. The identification of irisin has not only opened up new possibilities for monitoring metabolic and non-metabolic diseases but also presents a promising therapeutic target due to its multiple biological functions...
January 11, 2024: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://read.qxmd.com/read/38218016/a-path-analysis-investigation-into-menopausal-osteoporosis-sarcopenia-risk-and-their-impact-on-sleep-quality-depressive-symptoms-and-quality-of-life
#38
JOURNAL ARTICLE
Hui-Ling Lai, Chun-I Chen, Yu-Ching Lin, Liu-Chun Lu, Chiung-Yu Huang
PURPOSE: The objective was to investigate the relationships among disease characteristics, sarcopenia risk, bone function, sleep quality, depressive symptoms, and health-related quality of life in menopausal women. Additionally, we also examined the potential mediating role of coping in the relationship between these factors and health outcomes for individuals with osteoporosis. METHODS: In a cross-sectional approach, 201 participants were referred by a physician from the Family Medicine Department during their outpatient visits at a general hospital in Southern Taiwan...
December 27, 2023: International Journal of Orthopaedic and Trauma Nursing
https://read.qxmd.com/read/38214906/cerebrovascular-adaptations-to-habitual-resistance-exercise-with-aging
#39
REVIEW
Elric Y Allison, Baraa K Al-Khazraji
Resistance training (RT) is associated with improved metabolism, bone density, muscular strength, and lower risk of osteoporosis, sarcopenia, and cardiovascular disease. Although RT imparts many physiological benefits, cerebrovascular adaptations to chronic RT are not well defined. Participation in RT is associated with greater resting peripheral arterial diameters, improved endothelial function, and general cardiovascular health, whereas simultaneously linked to reductions in central arterial compliance. Rapid blood pressure fluctuations during resistance exercise, combined with reduced arterial compliance, could lead to cerebral microvasculature damage and subsequent cerebral hypoperfusion...
March 1, 2024: American Journal of Physiology. Heart and Circulatory Physiology
https://read.qxmd.com/read/38202104/effect-of-a-multicomponent-intervention-with-tele-rehabilitation-and-the-vivifrail%C3%A2-exercise-programme-on-functional-capacity-after-hip-fracture-study-protocol-for-the-activefls-randomized-controlled-trial
#40
JOURNAL ARTICLE
Bernardo Abel Cedeno-Veloz, Irache Casadamon-Munarriz, Alba Rodríguez-García, Lucia Lozano-Vicario, Fabricio Zambom-Ferraresi, María Gonzalo-Lázaro, Ángel María Hidalgo-Ovejero, Mikel Izquierdo, Nicolás Martínez-Velilla
INTRODUCTION: Hip fractures are the most common fracture leading to hospitalization and are associated with high costs, mortality rates and functional decline. Although several guidelines exist for preventing new fractures and promoting functional recovery, they tend to focus on osteoporosis treatment and do not take into account the complexity of frailty in older adults and geriatric syndromes, which are important factors in individuals at risk of suffering from frailty fractures. Moreover, most health systems are fragmented and are incapable of providing appropriate management for frail and vulnerable individuals who are at risk of experiencing fragility fractures...
December 23, 2023: Journal of Clinical Medicine
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