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https://www.readbyqxmd.com/read/27688592/release-of-experimental-retinal-vein-occlusions-by-direct-intraluminal-injection-of-ocriplasmin
#1
Marc D de Smet, Jean Marie Stassen, Thijs C M Meenink, Tom Janssens, Valérie Vanheukelom, Gerrit J L Naus, Maarten J Beelen, Bart Jonckx
PURPOSE: Retinal vein occlusions (RVO) are a major cause of vision loss in people aged 50 years and older. Current therapeutic options limit the consequences of RVO but do not eliminate the cause. Cannulation of the involved vessel and removal of the clot may provide a more permanent solution with a less demanding follow-up. However, cannulation of smaller retinal veins remains challenging. This paper explores the use of ocriplasmin (recombinant plasmin without its kringles) to clear RVO, using a robotic micromanipulator...
September 28, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27676261/robotic-assisted-cannulation-of-occluded-retinal-veins
#2
Marc D de Smet, Thijs C M Meenink, Tom Janssens, Valerie Vanheukelom, Gerrit J L Naus, Maarten J Beelen, Caroline Meers, Bart Jonckx, Jean-Marie Stassen
PURPOSE: To develop a methodology for cannulating porcine retinal venules using a robotic assistive arm after inducing a retinal vein occlusion using the photosensitizer rose bengal. METHODOLOGY: Retinal vein occlusions proximal to the first vascular branch point were induced following intravenous injection of rose bengal by exposure to 532nm laser light delivered by slit-lamp or endolaser probe. Retinal veins were cannulated by positioning a glass catheter tip using a robotically controlled micromanipulator above venules with an outer diameter of 80μm or more and performing a preset piercing maneuver, controlled robotically...
2016: PloS One
https://www.readbyqxmd.com/read/27664228/management-of-postvitrectomy-retinal-detachment-due-to-multiple-laser-induced-retinal-holes
#3
Vinod Kumar, Shreyans Jain, Parijat Chandra, Atul Kumar
A 25-year-old man presented with retinal detachment in his right eye 20 days after pars plana vitrectomy, epiretinal membrane peeling and endolaser assisted panretinal photocoagulation performed for non-resolving vitreous haemorrhage secondary to Eales disease. Inferior retina of the right eye showed multiple (around 120) retinal holes in relation to the previous photocoagulation marks. The patient was managed with repeat vitrectomy, endolaser and silicone oil infusion. The aetiology of multiple holes, precautions to prevent them and their management are described...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27614461/the-results-of-25-gauge-vitreoretinal-surgery-for-optic-disc-pit-associated-maculopathy-a-report-of-three-cases-and-mini-review-of-the-literature
#4
Alper Mete, Peykan Türkçüoğlu, Sabit Kimyon, Kıvanç Güngör
PURPOSE: We report the outcomes of three consecutive patients with optic disc pit-associated maculopathy who were treated with 25-gauge pars plana vitrectomy, internal limiting membrane (ILM) peeling, fluid-air exchange, barrage endolaser, and sulfur hexafluoride (SF6) gas tamponade. CASE REPORT: Patients with optic disc pit-associated maculopathy were treated with 25-gauge pars plana vitrectomy followed by ILM peeling, fluid-air exchange, barrage endolaser, and gas tamponade with 20 % SF6...
September 10, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27533771/vitreoretinal-surgery-for-patients-with-severe-exudative-and-proliferative-manifestations-of-retinal-capillary-hemangioblastoma-because-of-von-hippel-lindau-disease
#5
Remzi Avci, Sami Yilmaz, Umit Ubeyt Inan, Berkant Kaderli, Sadik Gorkem Cevik
PURPOSE: The evaluation of long-term results of vitreoretinal surgery and retinal capillary hemangioblastoma (RCH) resection in patients with complicated retinal detachment (RD) secondary to RCHs. METHODS: Twelve eyes of 12 patients were operated on with vitreoretinal surgery, including occlusion of afferent and efferent feeder vessels with endodiathermy and endolaser photocoagulation, and subsequent resection of RCHs. The long-term anatomical and visual outcomes were retrospectively evaluated...
August 16, 2016: Retina
https://www.readbyqxmd.com/read/27492730/incidence-and-risk-factors-associated-with-retinal-redetachment-after-silicone-oil-removal-in-the-african-population
#6
Kazim Dhalla, Imani Kapesa, Capucine Odouard
The purpose of this study was to investigate the incidence and risk factors associated with retinal redetachment after silicone oil (SO) removal in the African population. A retrospective cohort study was performed on patients undergoing SO removal over a period of 4 years. The risk factors assessed were (1) characteristics of the retinal detachments including type of retinal detachment, type, number and location of the retinal tears, and proliferative vitreoretinopathy (PVR) score, and (2) surgical factors including type of silicone oil used, use of laser prior to SO removal, and location of the laser (360° or around the tear only)...
August 4, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27462264/bilateral-simultaneous-rhegmatogenous-retinal-detachment-following-laser-in-situ-keratomileusis
#7
Erhan Yumusak, Kemal Ornek, Fatma Ozkal
A 21-year-old woman developed simultaneous rhegmatogenous retinal detachment after laser in situ keratomileusis (LASIK) in both eyes. She underwent pars plana vitrectomy surgery combined with endolaser photocoagulation and silicone oil tamponade in the right eye. A week later, pneumatic retinopexy was done in the left eye. As the retinal tear did not seal, 360° scleral buckling surgery was performed and retina was attached. Bilateral simultaneous rhegmatogenous retinal detachment after LASIK for correction of myopia can be a serious complication...
May 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27334604/comparison-of-pain-experience-during-23-g-vitreoretinal-surgery-under-topical-and-retrobulbar-anesthesia
#8
Alper Mete, Oguzhan Saygılı, Sabit Kimyon, Can Pamukcu, Seda Çeri, Kıvanç Güngör, Mithat Temizer
The objective of this study is to compare pain and discomfort scores of patients during 23-G vitreoretinal surgery under topical and retrobulbar anesthesia without using sedation. A total of 157 patients with various vitreoretinal disorders were included in this study. Patients were randomly divided into two groups: topical (group 1, n = 76) and retrobulbar anesthesia (group 2, n = 81). Patients underwent 23-G vitreoretinal surgery without using sedation. All patients rated the level of experienced pain during the surgical procedure using a visual analogue pain scale...
June 22, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27327294/retinal-detachment-after-subretinal-stem-cell-transplantation
#9
Ella H Leung, Harry W Flynn, Thomas A Albini, Carlos A Medina
A 60-year-old man with Stargardt's macular dystrophy and visual acuity of 20/400 in the right eye and 20/60 in the left eye underwent a subretinal injection of autologous bone marrow-derived stem cells in the right eye. The patient developed a retinal detachment in the right eye 2 months later that was initially treated with a scleral buckle, but the patient subsequently developed a recurrent retinal detachment with proliferative vitreoretinopathy. A pars plana vitrectomy, membrane peel, fluid-air exchange, endolaser, and silicone oil injection were then performed...
June 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27277708/akreos-adapt-ao-intraocular-lens-opacification-after-vitrectomy-in-a-diabetic-patient-a-case-report-and-review-of-the-literature
#10
Dan Cao, Hongyang Zhang, Cheng Yang, Liang Zhang
BACKGROUND: Postoperative optic opacification of hydrophilic acrylic intraocular lenses (IOLs) is an uncommon complication leading to IOL explantation. In the past decade, several studies reported that the granular deposits responsible for the opacification were probably calcium and phosphate salts; however, the exact mechanism causing calcification of IOLs is unknown. The aim of this study is to describe clinical and laboratory findings of a case of late postoperative opacification of an aspheric hydrophilic acrylic IOL (Akreos Adapt AO) after vitrectomy...
2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27239578/perfluorocarbon-liquid-migration-into-the-subarachnoid-space-in-a-patient-with-morning-glory-syndrome
#11
Masood Naseripour, Adel Ghasempour, Khalil Ghasemi Falavarjani, Mostafa Sultan Sanjari, Maryam Yousefi
PURPOSE: To report a case of perfluorocarbon liquid (PFCL) migration into the subarachnoid space at the time of vitreoretinal surgery in a patient with morning glory syndrome associated retinal detachment. CASE REPORT: A 9-year-old girl underwent pars plana vitrectomy and silicone oil injection for retinal detachment associated with morning glory syndrome. PFCL was used for retinal stabilization before endolaser photocoagulation. The retina detached, and repeated vitrectomy and silicone oil injection was performed...
March 2015: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27065372/25-gauge-vitrectomy-and-incomplete-drainage-of-subretinal-fluid-for-the-treatment-of-primary-rhegmatogenous-retinal-detachment
#12
Stratos Gotzaridis, Efstathios Liazos, Petros Petrou, Ilias Georgalas
BACKGROUND AND OBJECTIVE: To evaluate the anatomical and functional results of 25-gauge (G) vitrectomy with incomplete drainage of subretinal fluid for the treatment of primary rhegmatogenous retinal detachment. PATIENTS AND METHODS: A retrospective, noncomparative interventional case series including 100 consecutive patients who underwent 25-G vitrectomy, incomplete drainage of subretinal fluid, cryolaser or endolaser, and SF6 gas tamponade for the treatment of primary rhegmatogenous retinal detachment was performed...
April 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/26929884/the-effect-of-temperature-changes-in-vitreoretinal-surgery
#13
Mario R Romano, Vito Romano, Alessandro Mauro, Martina Angi, Ciro Costagliola, Luigi Ambrosone
PURPOSE: Recent studies on temperature control in biology and medicine have found the temperature as a new instrument in healthcare. In this manuscript, we reviewed the effects of temperature and its potential role in pars plana vitrectomy. We also examined the relationship between intraocular pressure, viscosity, and temperature in order to determine the best balance to manipulate the tamponades during the surgery. METHODS: A literature review was performed to identify potentially relevant studies on intraocular temperature...
February 2016: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/26872607/coat-s-like-vasculopathy-in-leber-congenital-amaurosis-secondary-to-homozygous-mutations-in-crb1-a-case-report-and-discussion-of-the-management-options
#14
Somar M Hasan, Arwa Azmeh, Osama Mostafa, Andre Megarbane
BACKGROUND: Mutations in the CRB1 gene are associated with variable phenotypes of severe retinal dystrophies, and retinal dystrophies resulting from CRB1 mutations may be accompanied by specific fundus features such as coat's like vasculopathy in retinitis pigmentosa patients. This is the first report of the occurrence of coat's like vasculopathy in a patient diagnosed with Leber congenital amaurosis caused by a CRB1 mutation. CASE PRESENTATION: An 18-year old Syrian female patient presented with bilateral gradual loss of vision since early childhood, with recent deterioration in her left eye...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/26731207/a-comparison-of-immediate-and-delayed-vitrectomy-for-the-management-of-vitreous-hemorrhage-due-to-proliferative-diabetic-retinopathy
#15
COMPARATIVE STUDY
Janelle M Fassbender, Ahmet Ozkok, Hannah Canter, Shlomit Schaal
BACKGROUND AND OBJECTIVE: To compare immediate and delayed vitrectomy for the management of vitreous hemorrhage (VH) due to proliferative diabetic retinopathy (PDR). PATIENTS AND METHODS: Retrospective review of 134 eyes receiving vitrectomy for non-clearing, PDR-associated VH. Primary outcome was area under the vision curve (AUC) in patients receiving immediate (< 30 days) versus delayed (> 30 days) vitrectomy with endolaser. RESULTS: Forty-six eyes were included, with 17 undergoing immediate (< 30 days) vitrectomy with endolaser and 29 undergoing delayed (> 30 days) vitrectomy with endolaser...
January 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/26679062/visual-recovery-after-autologous-retinal-pigment-epithelium-and-choroidal-patch-in-a-patient-with-choroidal-neovascularization-secondary-to-angioid-streaks-long-term-results
#16
Barbara Parolini, Micol Alkabes, Andrea Baldi, Sajish Pinackatt
PURPOSE: To describe a successfully treated case of autologous retinal pigment epithelium and choroidal patch in a patient with choroidal neovascularization secondary to angioid streaks. METHODS: A 53-year-old man with angioid streaks and a subfoveal choroidal neovascularization underwent autologous retinal pigment epithelium and choroid transplantation. Lensectomy, pars plana vitrectomy, 200° peripheral temporal retinotomy, isolation of the patch, endolaser, and silicone oil tamponade 1,000 cts were performed...
October 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/26656086/intraoperative-optical-coherence-tomography-in-macula-involving-rhegmatogenous-retinal-detachment-repair-with-pars-plana-vitrectomy-and-perfluoron
#17
O Toygar, C D Riemann
PurposeTo investigate microanatomical relationships during surgical repair of macula involving retinal detachment with pars plana vitrectomy (PPV) and perfluoron (PFO) with a microscope-integrated intraoperative optical coherence tomography (iOCT) device.Patients and methodsThis consecutive case series included nine eyes of nine patients with macula involving retinal detachment operated by a single surgeon at the Cincinnati Eye Institute. All patients underwent PPV, PFO injection, endolaser, and air-fluid exchange...
January 2016: Eye
https://www.readbyqxmd.com/read/26646832/delayed-boston-keratoprosthesis-exchange-due-to-a-preceding-vitreoretinal-surgery-with-intraoperative-choroidal-detachment
#18
María Isabel Relimpio López, María Gessa Sorroche, Antonio Manuel Garrido Hermosilla, Teresa Laborda Guirao, Francisco Espejo Arjona, Enrique Rodríguez de la Rúa Franch
PURPOSE: The aim is to describe the main characteristics of an anterior/posterior segment surgery and how to resolve intraoperative complications. Setting/Venue: The anterior and posterior segment surgical video was created at the Department of Ophthalmology, Virgin Macarena University Hospital, Seville, Spain. METHODS: We present the case of a male with Stevens-Johnson syndrome and severe limbal deficiency who needed a Boston type 1 keratoprosthesis, reaching a visual acuity of 0...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/26611845/surgical-challenges-and-outcomes-of-rhegmatogenous-retinal-detachment-in-albinism
#19
M K Sinha, J Chhablani, B S Shah, R Narayanan, S Jalali
PURPOSE: To report the outcomes and surgical difficulties during rhegmatogenous retinal detachment (RRD) repair in patients with albinism. METHODS: Retrospective analysis of 10 eyes of 9 patients with albinism that underwent RRD repair was performed. Collected data included demographic details, preoperative examination details, surgical procedure, surgical difficulties, anatomical, and visual outcomes. Outcome measures were retinal reattachment and visual acuity at the last follow-up...
March 2016: Eye
https://www.readbyqxmd.com/read/26604668/lowered-intraocular-pressure-in-a-glaucoma-patient-after-intravitreal-injection-of-ocriplasmin
#20
Michael McClintock, Mathew W MacCumber
We report the case of a glaucoma patient who received a single intravitreal injection of 125 µg ocriplasmin for vitreomacular traction in the right eye. The patient had bilateral advanced glaucoma and had previously undergone an implantation of an Ahmed glaucoma valve in the right eye and trabeculectomy in both eyes. The patient was using three topical ophthalmic intraocular pressure (IOP)-lowering medications on the day of injection. Baseline uncorrected Snellen visual acuity was 20/80-1 and IOP was 19 mmHg...
2015: Clinical Ophthalmology
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