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https://www.readbyqxmd.com/read/28814050/segmental-contributions-to-sagittal-plane-whole-body-angular-momentum-when-using-powered-compared-to-passive-ankle-foot-prostheses-on-ramps
#1
Nathaniel T Pickle, Anne K Silverman, Jason M Wilken, Nicholas P Fey
Understanding the effects of an assistive device on dynamic balance is crucial, particularly for robotic leg prostheses. Analyses of dynamic balance commonly evaluate the range of whole-body angular momentum (H). However, the contributions of individual body segments to overall H throughout gait may yield futher insights, specifically for people with transtibial amputation using powered prostheses. We evaluated segment contributions to H using Statistical Parametric Mapping to assess the effects of prosthesis type (powered vs passive) and ramp angle on segmental coordination...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813856/quantifying-the-benefit-of-the-kinetic-crutch-tip
#2
Fatemeh Rasouli, David Huizenga, Tim Hess, Ismet Handzic, Kyle B Reed
This research focuses on the difference between the Kinetic Crutch Tip (KCT) and a Standard Rubber Tip. Additionally, the effect of KCT stiffness on the crutch gait cycle and the reaction forces were investigated. This study also examined the maximum backward angle that a crutch is able to move forward without any external forces as well as the ratio of positive to negative horizontal forces were considered. The results were obtained in two ways: one by having subjects walk on the crutches and another to reduce the variability of human walking by measuring the resulting motion only using weights attached to the crutch tip...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813842/using-wearable-physiological-sensors-to-predict-energy-expenditure
#3
Kimberly A Ingraham, Daniel P Ferris, C David Remy
Lower-limb assistive robotic devices are often evaluated by measuring a reduction in the user's energy cost. Using indirect calorimetry to estimate energy cost is poorly suited for real-time estimation and long-term collection. The goal of this study was to use data from wearable sensors to predict energy cost with better temporal resolution and less variability than breath measurements. We collected physiological data (heart rate, electrodermal activity, skin temperature) and mechanical data (EMG, accelerometry) from three healthy subjects walking on a treadmill at various speeds on level ground, inclined, and backwards...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28759977/effects-of-progressive-backward-body-weight-suppoted-treadmill-training-on-gait-ability-in-chronic-stroke-patients-a-randomized-controlled-trial
#4
Kyung Hun Kim, Kyoung Bo Lee, Young-Hyeon Bae, Shirley S M Fong, Suk Min Lee
BACKGROUND AND OBJETIVE: A stroke patient with hemiplegic gait is generally described as being slow and asymmetric. Body weight-supported treadmill training and backward gait training are recent additions to therapeutic gait trainings that may help improve gait in stroke patient with hemiplegic gait. Therefore, we examined the effect of progressive backward body weight-supported treadmill training on gait in chronic stroke patients with hemiplegic gait. METHODS: Thirty subjects were divided to the experimental and control groups...
July 25, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28754624/dynamics-of-dimeric-kinesins-limping-effect-of-longitudinal-force-effects-of-neck-linker-extension-and-mutation-and-comparison-between-kinesin-1-and-kinesin-2
#5
Si-Kao Guo, Peng-Ye Wang, Ping Xie
Conventional kinesin (kinesin-1) can walk on microtubule filaments in an asymmetric hand-over-hand manner, exhibiting a marked alternation in the mean dwell time in successive steps. Here, we study computationally the asymmetric stepping dynamics of the kinesin-1 homodimer, revealing its origin and providing quantitative explanations of the available experimental data. The alternation in the mean dwell time in successive steps arises from the alternation in the mechanochemical coupling ratio, which is in turn caused by the alternation in the slight variation of the stretched neck linker length...
July 25, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28750748/flash-lag-effects-in-biological-motion-interact-with-body-orientation-and-action-familiarity
#6
Junzhu Su, Hongjing Lu
The ability to localize moving joints of a person in action is crucial for interacting with other people in the environment. However, it remains unclear how the visual system encodes the position of joints in a moving body. We used a paradigm based on a well-known phenomenon, the flash-lag effect, to investigate the mechanisms underlying joint localization in bodily movements. We first found that observers perceived a strong flash-lag effect in biological motion: when a briefly-flashed dot was presented physically in perfect alignment with a continuously moving limb, the flash dot was perceived to lag behind the position of the moving joint...
July 24, 2017: Vision Research
https://www.readbyqxmd.com/read/28746485/an-interview-with-steven-j-lindauer
#7
Steven J Lindauer
There are so many compliments to Dr. Steven Lindauer that is hard for one to figure where to start from… Well, travelling backwards in time, all the way to the year 2000, I went to Virginia to study English at Virginia Commonwealth University (VCU), in Richmond, Virginia, USA. During my daily walks to the English school, I used to pass by the School of Dentistry, where the Department of Orthodontics was. That was the place where my very first "contact" with the VCU happened. In 2015, 15 years later, I had the pleasure to go back to the VCU and spend two days with Dr...
May 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28727159/children-with-heavy-prenatal-alcohol-exposure-exhibit-atypical-gait-characteristics
#8
Tenille C Taggart, Roger W Simmons, Jennifer D Thomas, Edward P Riley
BACKGROUND: Impaired motor function in children with histories of prenatal exposure to alcohol has been previously reported but, to date, no studies using quantitatively-based analyses have been performed to assess gait in these children. METHODS: Gait of children with (n = 18) or without (n = 26) prenatal alcohol exposure was assessed using an electronically instrumented walkway. Children completed blocks of trials traversing the walkway with different combinations of walking condition (increased, self-paced, and decreased cadence) and direction (forward and backward)...
July 20, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28714798/foot-rollover-temporal-parameters-during-walking-straight-ahead-and-stepping-over-obstacles-obese-and-non-obese-postmenopausal-women
#9
David Silva, Ronaldo Gabriel, Helena Moreira, João Abrantes, Aurélio Faria
The aim of this study was to compare the temporal foot rollover data between walking straight ahead and stepping over obstacles for obese and non-obese postmenopausal women. Plantar pressure data were collected from 67 women. The initial, final, and duration of contact of 10 foot areas were measured. Both limbs of both groups showed a longer foot contact duration on the obstacle task. Significant temporal differences were found for both groups between straight ahead and crossing obstacles on the initial, final, and duration of contact for several foot areas...
July 17, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28694171/repeated-dose-28-day-oral-toxicity-study-of-deae-dextran-in-mice-an-advancement-in-safety-chemotherapeutics
#10
Anita K Bakrania, Bhavesh C Variya, Prem Madan, Snehal S Patel
Cancer has emerged as a global threat with challenges for safe chemotherapeutics. Most of the currently available anti-cancer drugs exhibit significant toxicity. Amongst novel agents, interferons have exhibited anti-proliferative and cytoprotective roles. However, due to stability drawbacks of interferons, we have identified an interferon inducer DEAE-Dextran, which resolves the stability issues. Based on the previous history of toxicity pertaining to the current chemotherapeutic agents, it is equally essential to determine the safety of DEAE-Dextran...
July 8, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28692837/influence-of-gait-mode-and-body-orientation-on-following-a-walking-avatar
#11
L Rens A Meerhoff, Harjo J de Poel, Tim W D Jowett, Chris Button
Regulating distance with a moving object or person is a key component of human movement and of skillful interpersonal coordination. The current set of experiments aimed to assess the role of gait mode and body orientation on distance regulation using a cyclical locomotor tracking task in which participants followed a virtual leader. In the first experiment, participants moved in the backward-forward direction while the body orientation of the virtual leader was manipulated (i.e., facing towards, or away from the follower), hence imposing an incongruence in gait mode between leader and follower...
July 7, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28667363/which-patient-reported-factors-predict-referral-to-spinal-surgery-a-cohort-study-among-4987-chronic-low-back-pain-patients
#12
Johanna M van Dongen, Miranda L van Hooff, Maarten Spruit, Marinus de Kleuver, Raymond W J G Ostelo
PURPOSE: It is unknown which chronic low back pain (CLBP) patients are typically referred to spinal surgery. The present study, therefore, aimed to explore which patient-reported factors are predictive of spinal surgery referral among CLBP patients. METHODS: CLBP patients were consecutively recruited from a Dutch orthopedic hospital specialized in spine care (n = 4987). The outcome of this study was referral to spinal surgery (yes/no), and was assessed using hospital records...
June 30, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28647194/prediction-of-6-minute-walk-performance-in-patients-with-peripheral-artery-disease
#13
Xi Chen, Julie A Stoner, Polly S Montgomery, Ana I Casanegra, Federico Silva-Palacios, Sixia Chen, Amanda E Janitz, Andrew W Gardner
BACKGROUND: Peripheral artery disease (PAD) is a highly prevalent disease that impairs walking ability. Walking tests, such as the 6-minute walk test (6MWT) and 4-meter walk test, are commonly used to assess exercise endurance and ambulatory function over a short distance, respectively. The 6MWT performance is predictive of PAD severity and disease outcomes, but it is not feasible in many clinical settings because it requires a long walkway to serve as the test route and lengthens clinic visits...
June 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28632102/effect-of-transient-perturbations-of-short-term-memory-on-target-directed-blind-locomotion
#14
Sarah Piekarski, Yves Lajoie, Nicole Paquet
It is difficult to walk without vision to a nearby destination if there is a time delay between watching the destination and walking toward it. Indeed, path deviation occurred when delays were introduced before initiating straight ahead blindfolded walking (R. A. Tyrrell, K. K., Rudolph, B. G., Eggers, & H. W. Leibowitz, 1993 ). The questions are whether the location of a 60-s delay in the walking path and whether performing a cognitive task during the delay influence the accuracy in reaching a previously seen target while walking without vision...
March 2, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28622756/effects-of-implied-motion-and-facing-direction-on-positional-preferences-in-single-object-pictures
#15
Stephen E Palmer, Thomas A Langlois
Palmer, Gardner, and Wickens studied aesthetic preferences for pictures of single objects and found a strong inward bias: Right-facing objects were preferred left-of-center and left-facing objects right-of-center. They found no effect of object motion (people and cars showed the same inward bias as chairs and teapots), but the objects were not depicted as moving. Here we measured analogous inward biases with objects depicted as moving with an implied direction and speed by having participants drag-and-drop target objects into the most aesthetically pleasing position...
July 2017: Perception
https://www.readbyqxmd.com/read/28539149/mobility-and-agility-during-locomotion-in-the-mark-iii-space-suit
#16
Conor R Cullinane, Richard A Rhodes, Leia A Stirling
INTRODUCTION: The Mark III (MIII) space suit assembly (SSAs) implements a multibearing, hard-material hip brief assembly (HBA). We hypothesize that: 1) the MIII HBA restricts operator mobility and agility which manifests in effects to gait parameters; 2) the waist bearing provides rotational motion, partially alleviating the restrictions; and 3) there are resistive, speed-dependent torques associated with the spinning bearings which further diminish mobility and agility. METHODS: A subject (Suited and Unsuited) performed two planetary tasks-walking forward (WF) and backward (WB)...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28512223/kinematics-of-the-lever-arm-swing-in-myosin-vi
#17
Mauro L Mugnai, D Thirumalai
Myosin VI (MVI) is the only known member of the myosin superfamily that, upon dimerization, walks processively toward the pointed end of the actin filament. The leading head of the dimer directs the trailing head forward with a power stroke, a conformational change of the motor domain exaggerated by the lever arm. Using a unique coarse-grained model for the power stroke of a single MVI, we provide the molecular basis for its motility. We show that the power stroke occurs in two major steps. First, the motor domain attains the poststroke conformation without directing the lever arm forward; and second, the lever arm reaches the poststroke orientation by undergoing a rotational diffusion...
May 30, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28474271/can-recovery-foot-placement-affect-older-adults-slip-fall-severity
#18
Shuaijie Wang, Xuan Liu, Anna Lee, Yi-Chung Pai
Following a slip occurred in the overground walking, a fall can be classified into two exclusive categories: feet-forward fall or split fall. The purposes of this study were to investigate whether the placement of the recovery foot would determine the slip types, the likelihood of fall, and the severity associated with each fall. The fall severity was estimated based on the impact velocity of body segments or trunk orientation upon fall arrest. One hundred ninety-five participants experienced a novel, unannounced slip while walking on a 7-m walkway...
August 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28443006/cognitive-resources-necessary-for-motor-control-in-older-adults-are-reduced-by-walking-and-coordination-training
#19
Ben Godde, Claudia Voelcker-Rehage
We examined if physical exercise interventions were effective to reduce cognitive brain resources recruited while performing motor control tasks in older adults. Forty-three older adults (63-79 years of age) participated in either a walking (n = 17) or a motor coordination (n = 15) intervention (1 year, 3 times per week) or were assigned to a control group (n = 11) doing relaxation and stretching exercises. Pre and post the intervention period, we applied functional MRI to assess brain activation during imagery of forward and backward walking and during counting backwards from 100 as control task...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28416189/the-validity-and-reliability-of-the-arabic-version-of-the-japanese-orthopedic-association-back-pain-evaluation-questionnaire-can-we-implement-it-in-saudi-arabia
#20
Saud Mohammed Alfayez, Abdullah Nasser Bin Dous, Abdullah Abdulaziz Altowim, Qais Abdulmohsin Alrabiei, Bandar Obaid Alsubaie, Waleed Mohammad Awwad
BACKGROUND: The Japanese Orthopedic Association designed their back pain evaluation questionnaire (JOABPEQ) which was proven to be feasible, reliable and valid. The questionnaire's validity and reliability were confirmed when it was implemented in patients with different cultural background. Since the JOABPEQ still has not been utilized in any of the Arabic countries, we present the Arabic version with its validity and reliability. METHODS: After ensuring an optimal forward-backward translation of the JOABPEQ, the Arabic version was distributed among 151 patients visiting our clinics from December 2015 to February 2016...
April 13, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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