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https://www.readbyqxmd.com/read/28532449/the-factor-structures-and-correlates-of-ptsd-in-post-conflict-timor-leste-an-analysis-of-the-harvard-trauma-questionnaire
#1
Alvin Kuowei Tay, Mohammed Mohsin, Susan Rees, Zachary Steel, Natalino Tam, Zelia Soares, Jessica Baker, Derrick Silove
BACKGROUND: Post-traumatic stress disorder (PTSD) is the most widely assessed form of mental distress in cross-cultural studies conducted amongst populations exposed to mass conflict and displacement. Nevertheless, there have been longstanding concerns about the universality of PTSD as a diagnostic category when applied across cultures. One approach to examining this question is to assess whether the same factor structure can be identified in culturally diverse populations as has been described in populations of western societies...
May 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28529561/serum-immunoreactivity-of-cancer-testis-antigen-oy-tes-1-and-its-tissues-expression-in-glioma
#2
Xisheng Li, Jun Yan, Rong Fan, Bin Luo, Qingmei Zhang, Yongda Lin, Sufang Zhou, Guorong Luo, Xiaoxun Xie, Shaowen Xiao
OY-TES-1 is a member of the cancer/testis antigen family that is expressed in healthy testis tissue and certain types of cancerous tissue. The present study aimed to analyze the expression pattern of OY-TES-1 and serum anti-OY-TES-1 antibody concentration in patients with glioma. OY-TES-1 mRNA was detected in 28/36 (78%) of glioma cases using conventional reverse transcription polymerase chain reaction (RT-PCR) analysis. RT-quantitative-PCR revealed that OY-TES-1 was expressed at a higher level in glioma tissues compared with normal adult tissues (with the exception of testis tissue)...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28511359/occurrence-of-chemical-contaminants-in-peri-urban-agricultural-irrigation-waters-and-assessment-of-their-phytotoxicity-and-crop-productivity
#3
Anna Margenat, Víctor Matamoros, Sergi Díez, Núria Cañameras, Jordi Comas, Josep M Bayona
Water scarcity and water pollution have increased the pressure on water resources worldwide. This pressure is particularly important in highly populated areas where water demand exceeds the available natural resources. In this regard, water reuse has emerged as an excellent water source alternative for peri-urban agriculture. Nevertheless, it must cope with the occurrence of chemical contaminants, ranging from trace elements (TEs) to organic microcontaminants. In this study, chemical contaminants (i.e., 15 TEs, 34 contaminants of emerging concern (CECs)), bulk parameters, and nutrients from irrigation waters and crop productivity (Lycopersicon esculentum Mill...
May 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28503772/refractory-thoracic-endometriosis-syndrome-with-bilateral-hemothorax
#4
Lannah L Lua, Kevin Tran, Jyoti Desai
Thoracic endometriosis syndrome (TES) is a rare disorder presenting with catamenial pneumothorax, hemothorax, hemoptysis or pulmonary nodules. Bilateral involvement is uncommon, and only a very few cases have been reported in the literature. We report a case of bilateral catamenial hemothorax in a patient with recurrent thoracic endometriosis. Despite multiple surgical interventions, the patient continued to develop hemopneumothorax coinciding with menses. Remission was finally achieved with the addition of gonadotropin-releasing hormone agonist, highlighting the effectiveness of postoperative adjuvant hormone therapy and supporting a combined surgical and medical approach in the treatment of TES in patients who desire future fertility...
May 15, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28498935/the-association-of-changes-in-dna-methylation-with-temperature-dependent-sex-determination-in-cucumber
#5
Yun-Song Lai, Xiaohui Zhang, Wei Zhang, Di Shen, Haiping Wang, Yudong Xia, Yang Qiu, Jiangping Song, Chenchen Wang, Xixiang Li
Cucumber (Cucumis sativus L.) is characterized by its diverse and flexible sexual types. Here, we evaluated the effect of low temperature (LT) exposure on cucumber femaleness under short-day conditions. Shoot apices were subjected to whole-genome bisulfate sequencing (WGBS), mRNA-seq, and sRNA-seq. The results showed that temperature had a substantial and global impact on transposable element (TE)-related small RNA-directed DNA methylation (RdDM) mechanisms, resulting in large amounts of CHH-type cytosine demethylation...
May 12, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28497797/suppression-of-cognitive-function-in-hyperthermia-from-the-viewpoint-of-executive-and-inhibitive-cognitive-processing
#6
Manabu Shibasaki, Mari Namba, Misaki Oshiro, Ryusuke Kakigi, Hiroki Nakata
Climate change has had a widespread impact on humans and natural systems. Heat stroke is a life-threatening condition in severe environments. The execution or inhibition of decision making is critical for survival in a hot environment. We hypothesized that, even with mild heat stress, not only executive processing, but also inhibitory processing may be impaired, and investigated the effectiveness of body cooling approaches on these processes using the Go/No-go task with electroencephalographic event-related potentials...
March 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28496309/effect-of-electromagnetic-fields-and-antioxidants-on-the-trace-element-content-of-rat-teeth
#7
Mehmet Sinan Dogan, Mehmet Cihan Yavas, Yasemin Yavuz, Sait Erdogan, İsmail Yener, İbrahim Simsek, Zeki Akkus, Veysel Eratilla, Abdulsamet Tanik, Mehmet Zulkuf Akdag
The purpose of this study was to examine the possible effect of extremely low-frequency electromagnetic fields (ELF-EMFs), from a high-voltage source, on rat teeth in terms of changes in trace elements (TEs) and the effect of antioxidants (melatonin [MLT] and Ganoderma lucidum [GL]) in counteracting these effects. We used adult male Wistar albino rats with a mean weight of 250-300 g and divided the rats into eight groups. The groups were subjected to an ELF-EMF that was applied with a high-voltage line for 8 hours/day for 26 days (Groups I, II, and III) or 52 days (Groups V, VI, and VII)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28493390/discrimination-of-a-nerve-fiber-that-is-the-origin-of-a-cauda-equina-tumor-using-acetylcholinesterase-staining
#8
Naosuke Kamei, Nobuhiro Tanaka, Koji Arihiro, Kazuyoshi Nakanishi, Shinji Kotaka, Nobuo Adachi, Mitsuo Ochi
Spinal nerve sheath tumors are well known to typically originate from dorsal sensory nerve roots. However, it is difficult to anatomically identify the origin in the case of cauda equina tumors. In this study, we aimed to ascertain whether a cauda equina nerve root removed with a nerve sheath tumor was a motor nerve using acetylcholinesterase (AchE) staining. Nerve rootlet sections removed with tumors were stained for AchE using the AchE Rapid Staining Kit. Additionally, we performed intraoperative motor-evoked potential (MEP) monitoring following either transcranial electrical stimulation (TES) or electrical stimulation of nerve rootlets...
May 11, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28493303/comprehensive-profiling-of-rhizome-associated-alternative-splicing-and-alternative-polyadenylation-in-moso-bamboo-phyllostachys-edulis
#9
Taotao Wang, Huiyuan Wang, Dawei Cai, Yubang Gao, Hangxiao Zhang, Yongsheng Wang, Chentao Lin, Liuyin Ma, Lianfeng Gu
Moso bamboo (Phyllostachys edulis) represents one of the fastest-spreading plants in the world, due in part to their well-developed rhizomes system. However, the post-transcriptional mechanism has not been comprehensively studied for the development of rhizome system in bamboo. We therefore used a combination of single-molecule long-read sequencing technology and polyadenylation site sequencing (PAS-seq) to re-annotate the bamboo genome, and genome-wide identify alternative splicing (AS) and alternative polyadenylation (APA) in the rhizomes system...
May 10, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28492983/target-enrichment-sequencing-in-cultivated-peanut-arachis-hypogaea-l-using-probes-designed-from-transcript-sequences
#10
Ze Peng, Wen Fan, Liping Wang, Dev Paudel, Dante Leventini, Barry L Tillman, Jianping Wang
Enabled by the next generation sequencing, target enrichment sequencing (TES) is a powerful method to enrich genomic regions of interest and to identify sequence variations. The objective of this study was to explore the feasibility of probe design from transcript sequences for TES application in calling sequence variants in peanut, an important allotetraploid crop with a large genome size. In this study, we applied an in-solution hybridization method to enrich DNA sequences of seven peanut genotypes. Our results showed that it is feasible to apply TES with probes designed from transcript sequences in polyploid peanut...
May 10, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28491150/dynamic-silencing-of-somatic-l1-retrotransposon-insertions-reflects-the-developmental-and-cellular-contexts-of-their-genomic-integration
#11
Manoj Kannan, Jingfeng Li, Sarah E Fritz, Kathryn E Husarek, Jonathan C Sanford, Teresa L Sullivan, Pawan Kumar Tiwary, Wenfeng An, Jef D Boeke, David E Symer
BACKGROUND: The ongoing mobilization of mammalian transposable elements (TEs) contributes to natural genetic variation. To survey the epigenetic control and expression of reporter genes inserted by L1 retrotransposition in diverse cellular and genomic contexts, we engineered highly sensitive, real-time L1 retrotransposon reporter constructs. RESULTS: Here we describe different patterns of expression and epigenetic controls of newly inserted sequences retrotransposed by L1 in various somatic cells and tissues including cultured human cancer cells, mouse embryonic stem cells, and tissues of pseudofounder transgenic mice and their progeny...
2017: Mobile DNA
https://www.readbyqxmd.com/read/28490417/accelerating-digital-mental-health-research-from-early-design-and-creation-to-successful-implementation-and-sustainment
#12
David C Mohr, Aaron R Lyon, Emily G Lattie, Madhu Reddy, Stephen M Schueller
Mental health problems are common and pose a tremendous societal burden in terms of cost, morbidity, quality of life, and mortality. The great majority of people experience barriers that prevent access to treatment, aggravated by a lack of mental health specialists. Digital mental health is potentially useful in meeting the treatment needs of large numbers of people. A growing number of efficacy trials have shown strong outcomes for digital mental health treatments. Yet despite their positive findings, there are very few examples of successful implementations and many failures...
May 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28486636/natural-variation-in-the-distribution-and-abundance-of-transposable-elements-across-the-caenorhabditis-elegans-species
#13
K M Laricchia, S Zdraljevic, D E Cook, E C Andersen
Transposons are mobile DNA elements that generate both adaptive and deleterious phenotypic variation thereby driving genome evolution. For these reasons, genomes have mechanisms to regulate transposable element (TE) activity. Approximately 12-16% of the Caenorhabditis elegans genome is composed of TEs, of which the majority are likely inactive. However, most studies of TE activity have been conducted in the laboratory strain N2, which limits our knowledge of the effects of these mobile elements across natural populations...
May 9, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28483707/higher-success-rate-with-transcranial-electrical-stimulation-of-motor-evoked-potentials-using-constant-voltage-stimulation-compared-with-constant-current-stimulation-in-patients-undergoing-spinal-surgery
#14
Hideki Shigematsu, Masahiko Kawaguchi, Hironobu Hayashi, Tsunenori Takatani, Eiichiro Iwata, Masato Tanaka, Akinori Okuda, Yasuhiko Morimoto, Keisuke Masuda, Yuu Tanaka, Yasuhito Tanaka
BACKGROUND CONTEXT: During spine surgery, the spinal cord is electrophysiologically monitored via transcranial electrical stimulation motor evoked potentials (TES-MEP) to prevent injury. TES-MEP involves the use of either constant-current or constant-voltage stimulation; however, there are few comparative data available regarding their ability to adequately elicit compound motor action potentials (CMAPs). We hypothesized that the success rates of TES-MEP recordings would be similar between constant-current and constant-voltage stimulation in patients undergoing spine surgery...
May 5, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28476688/ltr-retrotransposons-in-plants-engines-of-evolution
#15
REVIEW
Leonardo Galindo-González, Corinne Mhiri, Michael K Deyholos, Marie-Angèle Grandbastien
LTR retrotransposons are the most abundant group of transposable elements (TEs) in plants. Among them, Ty1-copia elements can fall close to genes, and therefore influence their expression and evolution. This review aims to examine how LTR retrotransposons, especially Ty1-copia elements, mediate gene evolution. Various stimuli, including polyploidization and biotic and abiotic elicitors, result in the transcription and movement of these retrotransposons, and can facilitate adaptation. The presence of cis-regulatory motifs in the LTRs are central to their stress-mediated responses and are shared with host stress-responsive genes, showing a complex evolutionary history in which TEs provide new regulatory units to genes...
May 2, 2017: Gene
https://www.readbyqxmd.com/read/28472469/piwi-interacts-with-chromatin-at-nuclear-pores-and-promiscuously-binds-nuclear-transcripts-in-drosophila-ovarian-somatic-cells
#16
Artem A Ilyin, Sergei S Ryazansky, Semen A Doronin, Oxana M Olenkina, Elena A Mikhaleva, Evgeny Y Yakushev, Yuri A Abramov, Stepan N Belyakin, Anton V Ivankin, Alexey V Pindyurin, Vladimir A Gvozdev, Mikhail S Klenov, Yuri Y Shevelyov
Piwi in a complex with Piwi-interacting RNAs (piRNAs) triggers transcriptional silencing of transposable elements (TEs) in Drosophila ovaries, thus ensuring genome stability. To do this, Piwi must scan the nascent transcripts of genes and TEs for complementarity to piRNAs. The mechanism of this scanning is currently unknown. Here we report the DamID-seq mapping of multiple Piwi-interacting chromosomal domains in somatic cells of Drosophila ovaries. These domains significantly overlap with genomic regions tethered to Nuclear Pore Complexes (NPCs)...
May 2, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28471386/transposable-elements-in-human-cancer-causes-and-consequences-of-deregulation
#17
REVIEW
Sumadi Lukman Anwar, Wahyu Wulaningsih, Ulrich Lehmann
Transposable elements (TEs) comprise nearly half of the human genome and play an essential role in the maintenance of genomic stability, chromosomal architecture, and transcriptional regulation. TEs are repetitive sequences consisting of RNA transposons, DNA transposons, and endogenous retroviruses that can invade the human genome with a substantial contribution in human evolution and genomic diversity. TEs are therefore firmly regulated from early embryonic development and during the entire course of human life by epigenetic mechanisms, in particular DNA methylation and histone modifications...
May 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28469420/in-silico-approach-for-characterization-and-comparison-of-repeats-in-the-genomes-of-oil-and-date-palms
#18
Jaire Alves Ferreira Filho, Lucas Soares de Brito, André Pereira Leão, Alexandre Alonso Alves, Eduardo Fernandes Formighieri, Manoel Teixeira Souza Júnior
Transposable elements (TEs) are mobile genetic elements present in almost all eukaryotic genomes. Due to their typical patterns of repetition, discovery, and characterization, they demand analysis by various bioinformatics software. Probably, as a result of the need for a complex analysis, many genomes publicly available do not have these elements annotated yet. In this study, a de novo and homology-based identification of TEs and microsatellites was performed using genomic data from 3 palm species: Elaeis oleifera (American oil palm, v...
2017: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/28468120/trace-element-concentrations-along-a-gradient-of-urban-pressure-in-forest-and-lawn-soils-of-the-paris-region-france
#19
Ludovic Foti, Florence Dubs, Jacques Gignoux, Jean-Christophe Lata, Thomas Z Lerch, Jérôme Mathieu, François Nold, Naoise Nunan, Xavier Raynaud, Luc Abbadie, Sébastien Barot
The concentration, degree of contamination and pollution of 7 trace elements (TEs) along an urban pressure gradient were measured in 180 lawn and wood soils of the Paris region (France). Iron (Fe), a major element, was used as reference element. Copper (Cu), cadmium (Cd), lead (Pb) and zinc (Zn) were of anthropogenic origin, while arsenic (As), chromium (Cr) and nickel (Ni) were of natural origin. Road traffic was identified as the main source of anthropogenic TEs. In addition, the industrial activity of the Paris region, especially cement plants, was identified as secondary source of Cd...
April 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28466841/arabidopsis-proteins-with-a-transposon-related-domain-act-in-gene-silencing
#20
Yoko Ikeda, Thierry Pélissier, Pierre Bourguet, Claude Becker, Marie-Noëlle Pouch-Pélissier, Romain Pogorelcnik, Magdalena Weingartner, Detlef Weigel, Jean-Marc Deragon, Olivier Mathieu
Transposable elements (TEs) are prevalent in most eukaryotes, and host genomes have devised silencing strategies to rein in TE activity. One of these, transcriptional silencing, is generally associated with DNA methylation and short interfering RNAs. Here we show that the Arabidopsis genes MAIL1 and MAIN define an alternative silencing pathway independent of DNA methylation and short interfering RNAs. Mutants for MAIL1 or MAIN exhibit release of silencing and appear to show impaired condensation of pericentromeric heterochromatin...
May 3, 2017: Nature Communications
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