Hong Xue, Hongyu Zhou, Qiliang Lou, Putao Yuan, Zhenhua Feng, Li Qiao, Jiateng Zhang, Hongwei Xie, Yang Shen, Qingliang Ma, Shiyu Wang, Boya Zhang, Huali Ye, Jiao Cheng, Xuewu Sun, Peihua Shi
Osteoarthritis is the most prevalent degenerative joint disease reported worldwide. Conventional treatment strategies mainly focus on medication and involve surgical joint replacement. The use of these therapies is limited by gastrointestinal complications and the lifespan of joint prostheses. Hence, safe and efficacious drugs are urgently needed to impede the osteoarthritis progression. Urolithin B, a metabolite of ellagic acid in the gut, exhibits anti-inflammatory and antioxidant properties; however, its role in osteoarthritis remains unclear...
March 11, 2024: Food & Function