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Systemic esclerosis

Jorge Rojas-Serrano, Helga Codina-Velásquez, Gabriel Medrano-Ramírez, J Abraham Simón, Olga Vera-Lastra, Janitzia Vázquez-Mellado
OBJECTIVE: To determine the cumulative incidence of severe organ involvement in Mexican patients with systemic sclerosis (SS) and diffuse scleroderma at 3 years from the onset of SS symptoms, and to compare itwith the cumulative incidence observed in a cohort of white patients with SS. PATIENTS AND METHOD: Patients with SS and diffuse scleroderma were evaluated within the first 2 years from the onset of SS symptoms and were included. An estimation of the cumulative incidence of severe involvement to the skin, kidney, heart, lungs, and gastrointestinal track at 3 years from the onset of SS symptoms was carried out...
January 2008: Reumatología Clinica
S Otero, J Batlle, I Bonaventura, Ll Brieva, E Bufill, A Cano, O Carmona, A Escartín, M Marco, E Moral, E Munteis, C Nos, I Pericot, H Perkal, Ll Ramió-Torrentà, C Ramo-Tello, A Saiz, J Sastre-Garriga, M Tintoré, J Vaqué, X Montalban
INTRODUCTION: The first epidemiological studies on multiple sclerosis (MS) around the world pictured a north to south latitudinal gradient that led to the first genetic and environmental pathogenic hypothesis. MS incidence seems to be increasing during the past 20 years based on recent data from prospective studies performed in Europe, America and Asia. This phenomenon could be explained by a better case ascertainment as well as a change in causal factors. The few prospective studies in our area together with the increase in the disease in other regions, justifies an epidemiological MS project in order to describe the incidence and temporal trends of MS...
May 16, 2010: Revista de Neurologia
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