keyword
MENU ▼
Read by QxMD icon Read
search

Neurocognitive function

keyword
https://www.readbyqxmd.com/read/29774174/outpatient-interventions-that-may-enhance-the-care-of-a-patient-with-co-existing-moyamoya-and-down-syndromes
#1
Anita Lwanga, Waldo Herrera, Katya Cruz Madrid, Antony Irungu
Moyamoya vasculopathy is a condition of chronic, progressive occlusion of the distal internal carotid arteries and the Circle of Willis. The resultant ischemia produces compensatory angiogenesis and the growth of a network of collateral blood vessels, which on angiography resemble a "puff of smoke" or "moyamoya" in Japanese. The objective of this case report is to describe the clinical course of a patient with Down and moyamoya syndromes and to enlighten clinicians about strategies that can be taken to enhance the care of similar patients...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29773664/cognitive-development-and-quality-of-life-associated-with-bpd-in-10-year-olds-born-preterm
#2
Sudhir Sriram, Michael D Schreiber, Michael E Msall, Karl C K Kuban, Robert M Joseph, T Michael O' Shea, Elizabeth N Allred, Alan Leviton
OBJECTIVES: To compare neurocognitive, language, executive function, academic achievement, neurologic and behavioral outcomes, and quality of life at age 10 years in children born extremely preterm who developed bronchopulmonary dysplasia (BPD) to children who did not develop BPD. METHODS: The Extremely Low Gestational Age Newborns study population included 863 children born extremely preterm whose BPD status before discharge was known had an IQ (Differential Ability Scales II [DAS II]) assessment at 10 years...
May 17, 2018: Pediatrics
https://www.readbyqxmd.com/read/29772816/alpha-mannosidosis-therapeutic-strategies
#3
REVIEW
Maria Rachele Ceccarini, Michela Codini, Carmela Conte, Federica Patria, Samuela Cataldi, Matteo Bertelli, Elisabetta Albi, Tommaso Beccari
Alpha-mannosidosis (α-mannosidosis) is a rare lysosomal storage disorder with an autosomal recessive inheritance caused by mutations in the gene encoding for the lysosomal α-d-mannosidase. So far, 155 variants from 191 patients have been identified and in part characterized at the biochemical level. Similarly to other lysosomal storage diseases, there is no relationship between genotype and phenotype in alpha-mannosidosis. Enzyme replacement therapy is at the moment the most effective therapy for lysosomal storage disease, including alpha-mannosidosis...
May 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29772485/neurocognitive-dysfunction-in-subjects-at-clinical-high-risk-for-psychosis-a-meta-analysis
#4
Wei Zheng, Qing-E Zhang, Dong-Bin Cai, Chee H Ng, Gabor S Ungvari, Yu-Ping Ning, Yu-Tao Xiang
Findings of neurocognitive dysfunction in subjects at Clinical High Risk for Psychosis (CHR-P) have been controversial. This meta-analysis systematically examined studies of neurocognitive functions using the MATRICS Consensus Cognitive Battery (MCCB) in CHR-P. An independent literature search of both English and Chinese databases was conducted by two reviewers. Standardized mean difference (SMD) was calculated using a random effects model to evaluate the effect size of the meta-analytic results. Six case-control studies (n = 396) comparing neurocognitive functions between CHR-P subjects (n = 197) and healthy controls (n = 199) using the MCCB were identified; 4 (66...
May 5, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29771819/sharing-as-a-model-for-understanding-division
#5
Alexa Ellis, Xiaosu Hu, Craig E Smith, Pamela E Davis-Kean, Ioulia Kovelman
Emerging research suggests that children's ability to divide is the best predictor of later arithmetic development. Although division is typically taught around grade 3, children much younger than this practice division when sharing and allocating resources (e.g. sharing food). To test the hypothesis that social sharing abilities are linked to the emergence of complex numerical division abilities, we examined sharing and division abilities in adults and children. The first study used functional near infrared spectroscopy to examine the neurocognitive bases of division in adults (N=28; age range: 18-23 years) during a task that evaluated their judgment of proportions in the context of sharing, as well as traditional numerical division tasks...
May 16, 2018: Neuroreport
https://www.readbyqxmd.com/read/29771285/increased-dolutegravir-peak-concentrations-in-people-living-with-hiv-aged-60-and-over-and-analysis-of-sleep-quality-and-cognition
#6
Emilie R Elliot, Xinzhu Wang, Suveer Singh, Bryony Simmons, Jaime H Vera, Robert F Miller, Colin Fitzpatrick, Graeme Moyle, Myra McClure, Marta Boffito
Background: Demographic data show an increasingly aging HIV population worldwide. Recent concerns over dolutegravir-related neuropsychiatric toxicity have emerged, particularly amongst older HIV patients. We describe the pharmacokinetics (PK) of dolutegravir (DTG) 50mg once daily in people living with HIV (PLWH) aged 60 and older. Additionally, to address the call for prospective neuropsychiatric toxicodynamic data, we evaluate changes in sleep quality and cognitive function after switching to abacavir (ABC)/lamivudine (3TC)/DTG, over 6 months in this population...
May 16, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29770225/quality-of-life-of-irradiated-brain-tumor-survivors-treated-with-donepezil-or-placebo-results-of-the-wfu-ccop-research-base-protocol-91105
#7
Michelle J Naughton, L Douglas Case, Ann Peiffer, Michael Chan, Volker Stieber, Dennis Moore, Steven Falchuk, James Piephoff, William Edenfield, Jeffrey Giguere, Monica Loghin, Edward G Shaw, Stephen R Rapp
Background: The health-related quality of life (HRQL) and fatigue of brain cancer survivors treated with donepezil or placebo for cognitive symptoms after radiation therapy were examined. Methods: One hundred ninety-eight patients who completed >30 Gy fractionated whole or partial brain irradiation at least 6 months prior to enrollment were randomized to either placebo or donepezil (5 mg for 6 weeks followed by 10 mg for 18 weeks) in a phase 3 trial. A neurocognitive battery, the Functional Assessment of Cancer Therapy-Brain (FACT-Br) and the Functional Assessment of Chronic Illness Therapy (FACIT)-fatigue, was administered at baseline, 12 weeks, and 24 weeks...
May 2018: Neuro-oncology Practice
https://www.readbyqxmd.com/read/29768190/a-bayesian-model-comparison-approach-to-test-the-specificity-of-visual-integration-impairment-in-schizophrenia-or-psychosis
#8
Tyler B Grove, Beier Yao, Savanna A Mueller, Merranda McLaughlin, Vicki L Ellingrod, Melvin G McInnis, Stephan F Taylor, Patricia J Deldin, Ivy F Tso
Impaired visual integration is well documented in schizophrenia and related to functional outcomes. However, it is unclear if this deficit is specific to schizophrenia, or characteristic of psychosis more broadly. To address this question, this study used a Bayesian model comparison approach to examine the evidence of three grouping models of visual integration performance in 116 individuals with schizophrenia (SZ), schizoaffective disorder (SA), bipolar disorder (BD) with or without a history of prominent psychosis (BDP+ and BDP-, respectively), or no psychiatric diagnosis (healthy controls; HC)...
May 7, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29762177/neuropsychological-phenotypes-among-men-with-and-without-hiv-disease-in-the-multicenter-aids-cohort-study
#9
Samantha A Molsberry, Yu Cheng, Lawrence Kingsley, Lisa Jacobson, Andrew J Levine, Eileen Martin, Eric N Miller, Cynthia A Munro, Ann Ragin, Ned Sacktor, James T Becker
OBJECTIVE: Mild forms of HIV-associated neurocognitive disorder (HAND) remain prevalent in the combination anti-retroviral therapy (cART) era. This study's objective was to identify neuropsychological subgroups within the Multicenter AIDS Cohort Study (MACS) based on the participant-based latent structure of cognitive function and to identify factors associated with subgroups. DESIGN: The MACS is a four-site longitudinal study of the natural and treated history of HIV disease among gay and bisexual men...
May 11, 2018: AIDS
https://www.readbyqxmd.com/read/29758392/effects-of-mindfulness-and-psychoeducation-on-working-memory-in-adult-adhd-a-randomised-controlled-fmri-study
#10
Katharina Bachmann, Alexandra P Lam, Peter Sörös, Manuela Kanat, Eliza Hoxhaj, Swantje Matthies, Bernd Feige, Helge Müller, Jale Özyurt, Christiane M Thiel, Alexandra Philipsen
Adult attention-deficit/hyperactivity disorder (ADHD) is a serious mental disorder associated with impaired neurocognitive performance related to working memory function. Recent clinical trials have suggested that mindfulness is a promising intervention in adults with ADHD. We performed a randomised controlled clinical trial to investigate working memory (WM) with an n-back task in adults with ADHD during fMRI before and after an 8-week mindfulness intervention (MAP) compared with psychoeducation (PE). ADHD symptoms were assessed using the self- and observer-rated Conners Adult ADHD Rating Scales (CAARS)...
May 7, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29755326/transient-hypothyroidism-during-lactation-arrests-myelination-in-the-anterior-commissure-of-rats-a-magnetic-resonance-image-and-electron-microscope-study
#11
Federico S Lucia, Jesús Pacheco-Torres, Susana González-Granero, Santiago Canals, María-Jesús Obregón, José M García-Verdugo, Pere Berbel
Thyroid hormone deficiency at early postnatal ages affects the cytoarchitecture and function of neocortical and telencephalic limbic areas, leading to impaired associative memory and in a wide spectrum of neurological and mental diseases. Neocortical areas project interhemispheric axons mostly through the corpus callosum and to a lesser extent through the anterior commissure (AC), while limbic areas mostly project through the AC and hippocampal commissures. Functional magnetic resonance data from children with late diagnosed congenital hypothyroidism and abnormal verbal memory processing, suggest altered ipsilateral and contralateral telencephalic connections...
2018: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29753255/cognition-social-cognition-and-functional-disability-in-early-stage-schizophrenia-a-study-from-southern-india
#12
Matthew M Kurtz, Subhashini Gopal, Sujit John, R Thara
In high-income countries a wealth of studies has revealed cognitive and social cognitive deficits in schizophrenia and a close relationship of these deficits to psychosocial functioning. Studies examining these illness features in middle and low-income countries are rare, particularly in early-stage samples. Sixty adult participants within 5 years of diagnosis with schizophrenia and 53 matched, healthy control were assessed with the MATRICS Consensus Cognitive Battery and the PEAT emotion identification task at study entry, and the WHODAS functioning scale one year later...
April 24, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29752216/primary-and-secondary-variants-of-psychopathy-in-a-volunteer-sample-are-associated-with-different-neurocognitive-mechanisms
#13
Arjun Sethi, Eamon McCrory, Vanessa Puetz, Ferdinand Hoffmann, Annchen R Knodt, Spenser R Radtke, Bartholomew D Brigidi, Ahmad R Hariri, Essi Viding
BACKGROUND: Recent work has indicated that there at least two distinct subtypes of psychopathy. Primary psychopathy is characterized by low anxiety and thought to result from a genetic predisposition, whereas secondary psychopathy is characterized by high anxiety and thought to develop in response to environmental adversity. Primary psychopathy is robustly associated with reduced neural activation to others' emotions and, in particular, distress. However, it has been proposed that the secondary presentation has different neurocognitive correlates...
April 12, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29751845/beneath-the-floor-re-analysis-of-neurodevelopmental-outcomes-in-untreated-hurler-syndrome
#14
Elsa G Shapiro, Chester B Whitley, Julie B Eisengart
BACKGROUND: Hurler syndrome (MPS IH), the severe, neurodegenerative form of type one mucopolysaccharidosis, is associated with rapid neurocognitive decline during toddlerhood and multi-system dysfunction. It is now standardly treated with hematopoietic cell transplantation (HCT), which halts accumulating disease pathology and prevents early death. While norm-based data on developmental functioning in untreated children have previously demonstrated neurocognitive decline, advances in methodology for understanding the cognitive functioning of children with neurodegenerative diseases have highlighted that the previous choice of scores to report results was not ideal...
May 11, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29751051/neurocognitive-effects-of-methylphenidate-in-adults-with-attention-deficit-hyperactivity-disorder-a-meta-analysis
#15
REVIEW
Michelle A Pievsky, Robert E McGrath
PIEVSKY, M. A., and R. E. McGrath. Neurocognitive effects of methylphenidate in adults with attention-deficit/hyperactivity disorder: A meta-analysis…NEUROSCI BIOBEHAV REV 81(1) XXX-XXX, 2017.- This meta-analysis summarized 21 double-blind randomized controlled trials with a mean study duration of 18 days comparing the neurocognitive functioning of adults with attention-deficit/hyperactivity disorder (ADHD) on methylphenidate vs placebo. Effect sizes were weighted using a random-effects model. Scores on neurocognitive measures and tests of driving ability were on average higher on methylphenidate than on placebo, g = ...
May 8, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29750912/ras-signalling-in-energy-metabolism-and-rare-human-diseases
#16
REVIEW
L Dard, N Bellance, D Lacombe, R Rossignol
The RAS pathway is a highly conserved cascade of protein-protein interactions and phosphorylation that is at the heart of signalling networks that govern proliferation, differentiation and cell survival. Recent findings indicate that the RAS pathway plays a role in the regulation of energy metabolism via the control of mitochondrial form and function but little is known on the participation of this effect in RAS-related rare human genetic diseases. Germline mutations that hyperactivate the RAS pathway have been discovered and linked to human developmental disorders that are known as RASopathies...
May 8, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29750366/feasibility-and-acceptability-of-maternal-choline-supplementation-in-heavy-drinking-pregnant-women-a-randomized-double-blind-placebo-controlled-clinical-trial
#17
Sandra W Jacobson, R Colin Carter, Christopher D Molteno, Ernesta M Meintjes, Marjanne Senekal, Nadine M Lindinger, Neil C Dodge, Steven H Zeisel, Christopher P Duggan, Joseph L Jacobson
BACKGROUND: Choline, an essential nutrient, serves as a methyl-group donor for DNA methylation and is a constituent of the neurotransmitter acetylcholine and a precursor to major components of cell membranes. Findings from animal studies suggest that choline supplementation during pregnancy may mitigate adverse effects of prenatal alcohol exposure on growth and neurocognitive function. We conducted a randomized, double-blind exploratory trial to examine feasibility and acceptability of a choline supplementation intervention during pregnancy...
May 11, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29746907/oscillatory-networks-of-high-level-mental-alignment-a-perspective-taking-meg-study
#18
R A Seymour, H Wang, G Rippon, K Kessler
Mentally imagining another's perspective is a high-level social process, reliant on manipulating internal representations of the self in an embodied manner. Recently Wang et al. (2016) showed that theta-band (3-7Hz) brain oscillations within the right temporo-parietal junction (rTPJ) and brain regions coding for motor/body schema contribute to the process of perspective-taking. Using a similar paradigm, we set out to unravel the extended functional brain network in detail. Increasing the angle between self and other perspective was accompanied by longer reaction times and increases in theta power within rTPJ, right lateral pre-frontal cortex (PFC) and right anterior cingulate cortex (ACC)...
May 7, 2018: NeuroImage
https://www.readbyqxmd.com/read/29745028/intellectual-and-academic-outcomes-after-pediatric-liver-transplantation-relationship-with-transplant-related-factors
#19
Soheil Afshar, Melanie Porter, Belinda Barton, Michael Stormon
As survival rates for pediatric liver transplantation continue to increase, research attention is turning towards long-term functional consequences, with particular interest in whether medical and transplant-related factors are implicated in neurocognitive outcomes. The relative importance of different factors is unclear, due to a lack of methodological uniformity, inclusion of differing primary diagnoses, variable transplant policies, and organ availability in different jurisdictions. This cross-sectional, single-site study sought to address various methodological limitations in the literature and the paucity of studies conducted outside of North America and Western Europe by examining the intellectual and academic outcomes of Australian pediatric liver transplant recipients (N = 40)...
May 9, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29744972/are-socio-emotional-and-neurocognitive-functioning-predictors-of-therapeutic-outcomes-for-adults-with-anorexia-nervosa
#20
Anna Oldershaw, Tony Lavender, Ulrike Schmidt
BACKGROUND: Emotional, social, and neurocognitive factors are theorised to maintain anorexia nervosa (AN). Yet whether they predict outcomes or relate to clinical change remains unclear. METHODS: Seventy-one consecutive adult outpatient eating disorder service referrals presenting with AN, who participated in a randomised controlled trial comparing 2 psychotherapies, were assessed for emotional processing, social cognition, and neurocognition pretherapy and posttherapy...
May 10, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
keyword
keyword
113111
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"