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https://www.readbyqxmd.com/read/28432128/do-the-microbiota-influence-vaccines-and-protective-immunity-to-pathogens-issues-of-sovereignty-federalism-and-points-testing-in-the-prokaryotic-and-eukaryotic-spaces-of-the-host-microbial-superorganism
#1
Andrew J Macpherson
In contrast to live attenuated vaccines, which are designed to induce immunity through a time-limited bloom in systemic tissues, the microbiota is a persistent feature of body surfaces, especially the intestine. The immune responses to the microbiota are idiosyncratic depending on the niche intimacy of different taxa and generally adapt the host to avoid overgrowth and maintain mutualism rather than to eliminate the organisms of that taxon. Both the microbiota and the host have so much molecular cross talk controlling each other, that the prokaryotic and the eukaryotic spaces of the host-microbial superorganism are federal rather than sovereign...
April 21, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28429996/are-athletes-doping-related-attitudes-predicted-by-their-perceptions-of-coaches-confrontation-efficacy
#2
Philip Sullivan, Parmida Razavi
BACKGROUND: The coaching process is complex and dynamic. Coaches are known to affect athlete attitudes indirectly, through athletes' perceptions and interpretations. This process has been verified with a variety of ethical behaviors. OBJECTIVES: The current study investigated the relationships between athletes' perceived doping confrontation efficacy of their coaches and athlete's anti-doping attitudes. METHODS: A sample of athletes (N = 96) completed a version of the Doping Confrontation Efficacy Scale that was modified to assess their perception of their coaches' anti-doping confrontation efficacy, and the PEAS (Performance Enhancing Attitude Scale), which assessed their performance-enhancing attitudes...
April 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28413941/psychobiological-protective-factors-modifying-the-association-between-age-and-sexual-health-in-men-findings-from-the-men-s-health-40-study
#3
Andreas Walther, Fiona Mahler, Rudolf Debelak, Ulrike Ehlert
Sexual health severely decreases with age. For males older than 40 years, erectile dysfunction (ED) is the most common sexual disorder. Although physical and psychological risk factors for ED have been identified, protective factors are yet to be determined. To date, no study has examined endocrine and psychosocial factors in parallel with regard to their modifying effect on the age-related increase in ED. Two hundred and seventy-one self-reporting healthy men aged between 40 and 75 years provided both psychometric data on sexual function and a set of potential psychosocial protective factors, and saliva samples for the analysis of steroid hormones and proinflammatory cytokines...
May 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28411413/sexual-intimacy-in-couples-is-associated-with-longer-telomere-length
#4
Tomás Cabeza de Baca, Elissa S Epel, Theodore F Robles, Michael Coccia, Amanda Gilbert, Eli Puterman, Aric A Prather
High-quality relationships have been shown to be beneficial for physical and mental health. This study examined overall relationship satisfaction and perceived stress as well as daily reports of partner support, partner conflict, and physical intimacy obtained over the course of one week in a sample of 129 high and low stress mothers. Telomere length was examined in whole blood, as well as the two cell subpopulations: peripheral blood mononuclear cells (PBMCs) and granulocytes. Telomerase activity was measured in PBMCs...
March 25, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28411144/management-of-sexuality-intimacy-and-menopause-symptoms-sims-in-ovarian-cancer-patients-expert-review
#5
REVIEW
Margaret Whicker, Jonathan Black, Gary Altwerger, Gulden Menderes, Jacqueline Feinberg, Elena Ratner
Issues of sexuality, intimacy, and early menopause significantly impact the quality of life of patients following the diagnosis and treatment of ovarian cancer. These are undertreated problems. Successful treatment requires the provider's awareness of the problem, ability to identify it, and willingness to treat it. Unfortunately many providers do not address these issues in the pre-treatment or perioperative period. Furthermore, patients do not often alert their providers to their symptoms. While systemic hormone therapy may improve many of the issues, they are not appropriate for all patients given their action on estrogen receptors...
April 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28405738/evaluation-of-mir-506-and-mir-4316-expression-in-early-and-non-invasive-diagnosis-of-colorectal-cancer
#6
Paweł Krawczyk, Tomasz Powrózek, Tomasz Olesiński, Adam Dmitruk, Joanna Dziwota, Dariusz Kowalski, Janusz Milanowski
PURPOSE: Examination of the entire colon by colonoscopy remains the golden standard for screening of colorectal cancer (CRC). However, patients are reluctant to perform invasive colonoscopies because of interference with their intimacy. Therefore, the potential use of non-invasive analysis of microRNAs expression in liquid biopsy as a novel biomarker for early CRC has investigated in several studies. In this study, we analyzed the expression of two novel microRNAs: miR-506 and miR-4316, which have never been examined in CRC...
April 12, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28403689/limits-excesses-and-pleasures-practices-and-discourses-of-sex-work-in-a-mexican-rural-community
#7
Rodrigo Parrini, Ana Amuchástegui, Cecilia Garibi
In Tomatlán, a small city on the Mexican Pacific Coast there is a tolerance zone in which a group of sex workers, separated from the rest of the city by a garbage dump, offer their services to local men. The women present themselves materially and symbolically as agents of regulation with respect to male sexuality, itself constructed as overwhelming and insatiable, which, were it not for services provided by the sex workers, would threaten the family-based social order. Through in-depth interviews with 19 sex workers and 5 municipal officials, this paper discusses how the sex gender system results in a series of borders that are both geographical and subjective...
April 13, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28398134/-i-told-her-this-is-your-life-relationship-dynamics-partner-support-and-adherence-to-antiretroviral-therapy-among-south-african-couples
#8
Amy Conroy, Anna Leddy, Mallory Johnson, Thulani Ngubane, Heidi van Rooyen, Lynae Darbes
Despite the important role of social relationships for health and wellbeing, little is known about how primary partners affect adherence to HIV care and treatment. We qualitatively explored how relationship dynamics and partner support influence adherence among couples from KwaZulu-Natal, South Africa. Twenty-four heterosexual couples with at least one HIV-positive partner completed semi-structured interviews on topics including relationship dynamics (intimacy or emotional closeness, communication, violence), experiences with HIV care and treatment and HIV-related social support...
April 11, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28397033/a-grassroots-community-dialogue-on-the-ethics-of-the-care-of-people-with-autism-and-their-families-the-stony-brook-guidelines
#9
Stephen G Post, John Pomeroy, Carla Keirns, Virginia Isaacs Cover, Michael Leverett Dorn
The increased recognition and reported prevalence of autism spectrum disorders (ASD) combined with the associated societal and clinical impact call for a broad grassroots community-based dialogue on treatment related ethical and social issues. In these Stony Brook Guidelines, which were developed during a full year of community dialogue (2010-2011) with affected individuals, families, and professionals in the field, we identify and discuss topics of paramount concern to the ASD constituency: treatment goals and happiness, distributive justice, managing the desperate hopes for a cure, sibling responsibilities, intimacy and sex, diagnostic ethics, and research ethics...
April 10, 2017: HEC Forum: An Interdisciplinary Journal on Hospitals' Ethical and Legal Issues
https://www.readbyqxmd.com/read/28387846/improving-diabetes-related-parent-adolescent-communication-with-individualized-feedback
#10
Dana K K May, Deborah A Ellis, Annmarie Cano, Bassem Dekelbab
To pilot a brief individualized feedback intervention to improve the communication skills of parents with an adolescent with type 1 diabetes.  Parent-adolescent dyads ( N  = 79) discussed a diabetes-related problem, while an interventionist rated the parent's communication skills to give feedback to the parents. Parents were then randomized to a brief feedback session to target person-centered communication skills or an educational session. Dyads discussed another diabetes care problem to assess for change in communication skills...
April 6, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28383929/personality-strengths-in-romantic-relationships-measuring-perceptions-of-benefits-and-costs-and-their-impact-on-personal-and-relational-well-being
#11
Todd B Kashdan, Dan V Blalock, Kevin C Young, Kyla A Machell, Samuel S Monfort, Patrick E McKnight, Patty Ferssizidis
Three studies using samples of people in romantic relationships were conducted to create a new individual difference measure of partner strengths in couples. The 2 perceptions of partner strengths included (1) appreciation of their use and effectiveness and (2) recognition of costs associated with their use. Factor analyses supported 2-factors and we found that greater appreciation of partner strengths predicted greater relationship satisfaction, commitment, investment, intimacy, self-expansion, and support for goal pursuit; recognizing significant costs with partner strengths was inversely related to several outcomes...
April 6, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28379852/unmet-supportive-care-needs-of-men-with-locally-advanced-and-metastatic-prostate-cancer-on-hormonal-treatment-a-mixed-methods-study
#12
Catherine Paterson, Sławomir Grzegorz Kata, Ghulam Nandwani, Debi Das Chaudhury, Ghulam Nabi
BACKGROUND: Men affected by prostate cancer who are undergoing hormone therapy can endure a range of symptoms that can adversely affect quality of life. Little research has been conducted to date, to understand the specific unmet supportive care needs of this patient group within the context of current service delivery. OBJECTIVE: The aim of this study was to understand the experiences of unmet supportive care needs of men affected by prostate cancer on hormone therapy in the United Kingdom...
April 4, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28375758/gender-role-attitudes-relationship-efficacy-and-self-disclosure-in-intimate-relationships
#13
Rebecca M Horne, Matthew D Johnson
Drawing from the intimacy process model and data from 5,042 individuals who remained partnered across Waves 1 and 2 of the German Panel Analysis of Intimate Relationships and Family Dynamics (pairfam), this study examined the contributions of traditional gender role attitudes and relationship efficacy in predicting levels of self-disclosure within an intimate relationship. Independent samples t-tests demonstrated females scored higher than males on self-disclosure and relationship efficacy measures but lower on traditional gender role attitudes...
February 28, 2017: Journal of Social Psychology
https://www.readbyqxmd.com/read/28368275/cryo-electron-microscopy-and-x-ray-crystallography-complementary-approaches-to-structural-biology-and-drug-discovery
#14
Catherine Vénien-Bryan, Zhuolun Li, Laurent Vuillard, Jean Albert Boutin
The invention of the electron microscope has greatly enhanced the view scientists have of small structural details. Since its implementation, this technology has undergone considerable evolution and the resolution that can be obtained for biological objects has been extended. In addition, the latest generation of cryo-electron microscopes equipped with direct electron detectors and software for the automated collection of images, in combination with the use of advanced image-analysis methods, has dramatically improved the performance of this technique in terms of resolution...
April 1, 2017: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/28366259/-different-perspectives-on-end-of-life-support-at-home
#15
REVIEW
Stéphane Tounkara, Emmanuelle Caudron
Hospital at home nursing teams support end-of-life. In the intimacy of the residence, the care fit the evolution of the state of the patient and his expectations. The communication within the team is essential to question the care, including in the ethical plan.
April 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28358543/dispositional-pathways-to-trust-self-esteem-and-agreeableness-interact-to-predict-trust-and-negative-emotional-disclosure
#16
Megan H McCarthy, Joanne V Wood, John G Holmes
Expressing our innermost thoughts and feelings is critical to the development of intimacy (Reis & Shaver, 1988), but also risks negative evaluation and rejection. Past research suggests that people with high self-esteem are more expressive and self-disclosing because they trust that others care for them and will not reject them (Gaucher et al., 2012). However, feeling good about oneself may not always be enough; disclosure may also depend on how we feel about other people. Drawing on the principles of risk regulation theory (Murray et al...
March 30, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28350660/why-women-request-labiaplasty
#17
Sarah C Sorice, Alexander Y Li, Francisco L Canales, Heather J Furnas
BACKGROUND: In recent years, labiaplasty has jumped in popularity, despite opposition to the procedure. In 2007, the American College of Obstetricians and Gynecologists declared the recommendation of cosmetic vaginal procedures to be "untenable," although in 2016 they allowed consideration of labiaplasty in adolescents if symptoms persist. The reasons for labiaplasty requests are not yet fully understood, and physician opposition limits patient access to surgical relief. METHODS: In this prospective study, 50 consecutive patients consulting about labiaplasty were given a questionnaire assessing 11 physical and appearance-related symptoms associated with elongated labia...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28343111/the-intimate-relationship-as-a-site-of-social-protection-partnerships-between-people-who-inject-drugs
#18
Tim Rhodes, Jake Rance, Suzanne Fraser, Carla Treloar
Public health research treats intimate partnerships as sites of risk management, including in the management of HIV and hepatitis C transmission. This risk-infused biomedical approach tends to undermine appreciation of the emotional and socially situated meanings of care in intimate partnerships. In this article we explore qualitative interview accounts of the care enacted in partnerships between people who inject drugs, drawing on a 2014 study of 34 couples and 12 individuals living in two locations of Australia...
May 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28338338/the-strategies-of-heterosexuals-from-large-metropolitan-areas-for-assessing-the-risks-of-exposure-to-hiv-or-other-sexually-transmitted-infections-from-partners-met-online
#19
Karolynn Siegel, Helen-Maria Lekas, Marie Onaga, Rachel Verni, Hamish Gunn
Heterosexuals' use of the Internet for meeting romantic or sexual partners is rapidly increasing, raising concerns about the Internet's potential to facilitate encounters that place individuals at risk for acquiring HIV or other sexually transmitted infections (STIs). For example, online sharing of personal information and self-revelations can foster virtual intimacy, promoting a false sense of familiarity that might accelerate progression to unprotected sex. Therefore, it is critical to understand how those who meet sexual partners online attempt to assess the possible risk of acquiring HIV or STIs posed by having unprotected sex with a new partner and decide whether to use a condom...
March 24, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28331734/the-treatment-approach-and-social-support-needs-for-patients-with-breast-cancer
#20
Pınar Soylar, Metin F Genç
OBJECTIVE: Breast cancer is the most common type of cancer in women both in developed and developing countries. It has a higher mortality rate in low and middle income countries due to the late-stage diagnosis. The principal aim of this study was to investigate what patients with breast cancer did before presenting to Turgut Özal Medical Center and its relationship with late stage diagnosis. The study also aimed to identify the level of patients' perceived social support. MATERIALS AND METHODS: The study included 200 patients with breast cancer who were treated at the chemotherapy unit during 2013 and 2014...
April 2016: Journal of Breast Health (2013)
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