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Injury burden

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https://www.readbyqxmd.com/read/29661290/factors-affecting-the-caloric-and-protein-intake-over-time-in-critically-ill-trauma-patients
#1
Tobias Haltmeier, Kenji Inaba, Beat Schnüriger, Stefano Siboni, Elizabeth Benjamin, Lydia Lam, Damon Clark, Demetrios Demetriades
BACKGROUND: Major trauma leads to increased nutritional requirements. However, little is known about the actual amount of calories and protein administered and the factors affecting the intake over time in critically ill trauma patients. METHODS: Prospective study including 100 trauma patients admitted to the Los Angeles County + University of Southern California Medical Center intensive care unit between March 2014 and October 2014. Inclusion criteria were age > 16 y, surgery at admission, and no oral nutrition...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29659841/incidence-and-mortality-from-adverse-effects-of-medical-treatment-in-the-uk-1990-2013-levels-trends-patterns-and-comparisons
#2
Raimundas Lunevicius, Juanita A Haagsma
Objective: To present an update on incidence and mortality from adverse effects (AEs) of medical treatment in the UK, its four countries and nine English regions between 1990 and 2013. Design: Descriptive epidemiological study on AEs of medical treatment. AEs are shown as a single cause-of-injury category from the Global Burden of Disease (GBD) 2013 study. Data sources: The GBD 2013 interactive data visualisation tools 'Epi Visualisation' and 'GBD Compare'...
April 12, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29658057/combined-effects-of-rat-schwann-cells-and-17%C3%AE-estradiol-in-a-spinal-cord-injury-model
#3
Zeinab Namjoo, Fateme Moradi, Roya Aryanpour, Abbas Piryaei, Mohammad Taghi Joghataei, Yusef Abbasi, Amir Hosseini, Sajad Hassanzadeh, Fatemeh Ranjbar Taklimie, Cordian Beyer, Adib Zendedel
Spinal cord injury (SCI) is a devastating traumatic event which burdens the affected individuals and the health system. Schwann cell (SC) transplantation is a promising repair strategy after SCI. However, a large number of SCs do not survive following transplantation. Previous studies demonstrated that 17β-estradiol (E2) protects different cell types and reduces tissue damage in SCI experimental animal model. In the current study, we evaluated the protective potential of E2 on SCs in vitro and investigated whether the combination of hormonal and SC therapeutic strategy has a better effect on the outcome after SCI...
April 15, 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29653245/improved-clinical-documentation-leads-to-superior-reportale-outcomes-an-accurate-representation-of-patient-s-clinical-status
#4
Adel Elkbuli, Steven Godelman, Ashley Miller, Dessy Boneva, Eileen Bernal, Shaikh Hai, Mark McKenney
INTRODUCTION: Clinical documentation can be an underappreciated. Trauma Centers (TCs) are now routinely evaluated for quality performance. TCs with poor documentation may not accurately reflect actual injury burden or comorbidities and can impact accuracy of mortality measures. Markers exist to adjust crude death rates for injury severity: observed over expected deaths (O/E) adjust for injury; Case Mix Index (CMI) reflects disease burden, and Severity of Illness (SOI) measures organ dysfunction...
April 10, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29651394/the-healing-effect-of-sesame-oil-camphor-and-honey-on-second-degree-burn-wounds-in-rat
#5
Reza Vaghardoost, Seyed GholamReza Mousavi Majd, Hamid Tebyanian, Hamid Babavalian, Leila Malaei, Mitra Niazi, Ali Javdani
BACKGROUND: Many studies were carried out to improve sophisticated dressings to accelerate healing processes and reduce the microbial burden in burn wounds. This study evaluated the healing effect of herbal ointment containing extract of sesame oil, camphor and honey on second degree burn wounds in rats in comparison with daily dressing oil vaseline. METHODS: Forty rats were randomly assigned to two equal groups. A deep second degree burn was formed on the back of each rat with using a standard burning technique...
January 2018: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29648957/asthma-among-household-youth-on-racial-minority-operated-farms-united-states-2008
#6
Girija Syamlal, Kitty Hendricks, Jacek M Mazurek
OBJECTIVES: Youth on farms are at risk for injuries and illnesses, including asthma, which continues to disproportionately affect minority groups. METHODS: For this study, the 2008 Minority Farm Operator Childhood Agricultural Injury Survey (M-CAIS) data were used to estimate the prevalence of asthma among youth aged 0-19 years living on racial minority-operated farms. Youth were considered to have a lifetime diagnosis of asthma based on an affirmative response to the question "Has he/she ever been diagnosed as having asthma by a health professional?" RESULTS: In 2008, of the estimated 37,400 youth (0-19 years) who lived on racial minority operated farms, 11% had asthma...
2018: Journal of Agromedicine
https://www.readbyqxmd.com/read/29644869/pearls-and-pitfalls-in-imaging-of-blunt-traumatic-thoracic-aortic-injury-a-pictorial-review
#7
Neeral R Patel, Elizabeth Dick, Nicola Batrick, Michael Jenkins, Elika Kashef
Blunt thoracic aortic injury (TAI) occurs most frequently as a sequelae of high impact deceleration such as high velocity road traffic accidents and falls from height. The burden of mortality and morbidity is high, however advances in pre-hospital care, diagnostic imaging and endovascular therapies have improved outcomes in this group of patients. Emergent treatment depends on accurate, early diagnosis by the radiologist. It is therefore of paramount importance that radiologists are familiar with both the direct (intimal flap, pseudoaneurysm, aortic contour irregularity and contrast extravasation) and indirect (periaortic haematoma) imaging findings of TAI...
April 12, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29629987/markedly-deranged-injury-site-metabolism-and-impaired-functional-recovery-in-acute-spinal-cord-injury-patients-with-fever
#8
Mathew J Gallagher, Argyro Zoumprouli, Isaac Phang, Jan M Schwab, Marcel A Kopp, Thomas Liebscher, Marios C Papadopoulos, Samira Saadoun
OBJECTIVES: To characterize the effect of fever after acute, traumatic spinal cord injury on injury site metabolism and patient outcome. DESIGN: Longitudinal cohort study. In 44 patients (London cohort), we determined the effect of fever on intrathecal injury site metabolism by analyzing 1,767 hours of intraspinal pressure and 759 hours of microdialysis data. We also determined the effect of fever burden, computed for the first 2 weeks in hospital, on neurologic outcome...
April 6, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29628742/risk-of-violence-related-injury-from-alcohol-consumption-and-its-burden-to-society-in-latin-america-and-the-caribbean
#9
Cheryl J Cherpitel, Yu Ye, Maristela Monteiro
Objectives: The risk for violence-related injury from drinking and attributable burden in the Latin American and Caribbean region was explored. Methods: A probability sample of 1024 emergency department patients reporting a violence-related injury was analyzed from 11 countries, using case-crossover fractional polynomial analysis of the number of drinks consumed prior to the event. Results: A dose-response relationship was observed with a six-fold increase in risk (RR=5...
January 2018: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/29628012/blunt-pharyngoesophageal-injuries-current-management-strategies
#10
G Barmparas, P H Navsaria, D Serna-Gallegos, A J Nicol, S Edu, A A Sayari, D R Margulies, E J Ley
BACKGROUND: Blunt pharyngoesophageal injuries pose a management challenge to the trauma surgeon. The purpose of this study was to explore whether these injuries can be managed expectantly without neck exploration. METHODS: The National Trauma Databank datasets 2007-2011 were reviewed for blunt trauma patients who sustained a pharyngeal injury, including an injury to the cervical esophagus. Patients who survived over 24 h and were not transferred from other institutions were divided into two groups based on whether a neck exploration was performed...
April 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29627943/therapeutic-potential-of-vitamin-e-and-its-derivatives-in-traumatic-brain-injury-associated-dementia
#11
Jan Dobrovolny, Martin Smrcka, Julie Bienertova-Vasku
Traumatic brain injury is one of the most common causes for intervention in neurosurgery. Apart from its acute consequence, it can represent a further burden on individuals as well as society by being associated with significant comorbidity-mainly early-onset dementia. Oxidative stress is one of the crucial mechanisms conferring the damage to nervous tissue, and it is believed it could be, to some extent, influenced by dietary composition, largely by antioxidants contained in the diet. Under stressful conditions, cell-derived reactive oxygen species in the brain can induce the formation of lipid peroxides and the shifting of redox homeostasis...
April 7, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29627883/platelet-transfusion-increases-risk-for-acute-respiratory-distress-syndrome-in-non-massively-transfused-blunt-trauma-patients
#12
George Kasotakis, Nichole Starr, Erek Nelson, Bedabrata Sarkar, Peter Ashley Burke, Daniel George Remick, Ronald Gary Tompkins
PURPOSE: While damage control resuscitation is known to confer a survival advantage in severely injured patients, high-ratio blood component therapy should be initiated only in carefully selected trauma patients, due to the morbidity associated with blood product use. With this project, we aim to identify the effect of platelet transfusion in non-massively transfused bluntly injured patients. METHODS: The Glue Grant database was retrospectively queried and severely injured blunt trauma patients who underwent non-massive transfusion were identified...
April 7, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29627841/preeclampsia-as-a-form-of-type-5-cardiorenal-syndrome-an-underrecognized-entity-in-women-s-cardiovascular-health
#13
Janani Rangaswami, Mario Naranjo, Peter A McCullough
BACKGROUND: Preeclampsia is a multisystem vascular disorder of pregnancy that remains a leading cause of maternal and fetal morbidity and mortality. Preeclampsia remains an underrecognized risk factor for future cardiovascular and kidney disease in women and represents the confluence of preexisting vascular risk factors with superimposed endothelial injury from placental mediated anti-angiogenic factors. SUMMARY: This review highlights the close relationship between preeclampsia and future cardiovascular and kidney disease...
April 4, 2018: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29625848/seizure-severity-is-correlated-with-severity-of-hypoxic-ischemic-injury-in-abusive-head-trauma
#14
Andra L Dingman, Nicholas V Stence, Brent R O'Neill, Stefan H Sillau, Kevin E Chapman
BACKGROUND: The objective of this study was to characterize hypoxic-ischemic injury and seizures in abusive head trauma. METHODS: We performed a retrospective study of 58 children with moderate or severe traumatic brain injury due to abusive head trauma. Continuous electroencephalograms and magnetic resonance images were scored. RESULTS: Electrographic seizures (51.2%) and hypoxic-ischemic injury (77.4%) were common in our cohort. Younger age was associated with electrographic seizures (no seizures: median age 13...
December 12, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29624091/excess-visceral-adiposity-is-associated-with-diabetic-retinopathy-in-a-multiethnic-asian-cohort-with-longstanding-type-2-diabetes
#15
Angela Moh, Kumari Neelam, Xiao Zhang, Chee Fang Sum, Subramaniam Tavintharan, Keven Ang, Simon Biing Ming Lee, Wern Ee Tang, Su Chi Lim
Purpose/Aim: Diabetic retinopathy (DR) is the most common diabetic microvascular complication, and it typically develops after 10 years of diabetes diagnosis. The primary aim of this study was to evaluate the association between adiposity and DR susceptibility among individuals with longstanding type 2 diabetes mellitus (T2D). MATERIALS AND METHODS: In this cross-sectional study, DR was assessed by fundus photography in 953 T2D subjects. DR prevalence by categories of T2D duration was evaluated...
April 6, 2018: Endocrine Research
https://www.readbyqxmd.com/read/29623603/injury-risk-burden-risk-matrices-and-risk-contours-in-team-sports-a-review-of-principles-practices-and-problems
#16
REVIEW
Colin W Fuller
The aim of this review was to provide insights into and a critical assessment of injury burden, risk matrices and risk contours in the context of team sports. Injury burden is the product of injury incidence and mean severity, and is normally reported as days' absence/1000 player-hours. An important feature of injury burden is that equal values can reflect quite different numerical combinations of injury incidence and severity. The timeframe over which injury burden affects a team depends on the incidence and severity values of the injuries sustained...
April 5, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29620580/do-initial-symptom-factor-scores-predict-subsequent-impairment-following-concussion
#17
Paul E Cohen, Alicia Sufrinko, Robert J Elbin, Michael W Collins, Aaron M Sinnott, Anthony P Kontos
OBJECTIVE: Symptom factors present during the first week following concussion may predict subsequent concussion outcomes and recovery duration. We hypothesized that a high loading on cognitive-fatigue-migraine and somatic factors would be predictive of neurocognitive impairment following concussion. We also hypothesized that the affective factor would be related to vestibular symptoms and impairment. DESIGN: Prospective repeated measures. SETTING: Concussion specialty clinic...
March 28, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29620578/facilitators-and-barriers-to-the-implementation-of-isprint-a-sport-injury-prevention-program-in-junior-high-schools
#18
Sarah A Richmond, Alex Donaldson, Alison Macpherson, William Bridel, Carla van den Berg, Caroline F Finch, Brent Hagel, Carolyn A Emery
OBJECTIVES: Sport injury is the leading cause of hospitalization in Canadian youth and represents a high burden to the health care system. This study aims to describe the facilitators and barriers to implementation of a sport injury prevention program in junior high school physical education (known as iSPRINT), previously shown to reduce the risk of sport-related injury in youth (age, 11-15 years). METHODS: Focus group data were mapped onto constructs from the Consolidated Framework for Implementation Research (CFIR)...
March 29, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29618653/the-inflammasome-potentiates-influenza-staphylococcus-aureus-superinfection-in-mice
#19
Keven M Robinson, Krishnaveni Ramanan, Michelle E Clay, Kevin J McHugh, Matthew J Pilewski, Kara L Nickolich, Catherine Corey, Sruti Shiva, Jieru Wang, John F Alcorn
Secondary bacterial respiratory infections are commonly associated with both acute and chronic lung injury. Influenza complicated by bacterial pneumonia is an effective model to study host defense during pulmonary superinfection due to its clinical relevance. Multiprotein inflammasomes are responsible for IL-1β production in response to infection and drive tissue inflammation. In this study, we examined the role of the inflammasome during viral/bacterial superinfection. We demonstrate that ASC-/- mice are protected from bacterial superinfection and produce sufficient quantities of IL-1β through an apoptosis-associated speck-like protein containing CARD (ASC) inflammasome-independent mechanism...
April 5, 2018: JCI Insight
https://www.readbyqxmd.com/read/29618187/effect-of-alcohol-use-on-emergency-department-length-of-stay-among-minimally-injured-patients-based-on-mechanism-of-injury-multicenter-observational-study
#20
Jeong Ho Park, Ju Ok Park, Young Sun Ro, Sang Do Shin
OBJECTIVE: This study aimed to evaluate the effect of alcohol use on emergency department (ED) length of stay (LOS) among minimally injured patients by mechanism of injury. METHODS: This was a retrospective study of injury surveillance data for injured patients (except poisoning), aged over 18 years, discharged home from the ED, and treated at seven academic EDs in Korea during 2008 to 2012. Patients were divided into alcohol-related and alcohol-unrelated groups based on self-report...
March 2018: Clinical and Experimental Emergency Medicine
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