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https://www.readbyqxmd.com/read/29227034/the-clinical-course-of-late-life-bipolar-disorder-looking-back-and-forward
#1
Annemiek Dols, Nicole Korten, Hannie Comijs, Sigfried Schouws, Moniek van Dijk, Ursula Klumpers, Aartjan Beekman, Ralph Kupka, Max Stek
OBJECTIVES: Little is known about the course of late-life bipolar disorder (LLBD). First, we studied patients with LLBD retrospectively with regard to age at first mood episode, onset polarity, predominant polarity and episode density and its associations with other clinical variables. Next, we examined prospectively the clinical course and its associated factors. METHODS: Data were used from a dynamic cohort (Dutch Older Bipolars [DOBi]) including 101 patients with LLBD (mean age of 68...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29227012/superior-anti-suicidal-effects-of-electroconvulsive-therapy-in-unipolar-disorder-and-bipolar-depression
#2
Chih-Sung Liang, Chi-Hsiang Chung, Pei-Shen Ho, Chia-Kuang Tsai, Wu-Chien Chien
OBJECTIVES: Electroconvulsive therapy (ECT) has long been believed to reduce suicidal tendencies in patients with affective disorders; however, ECT recipients, who constitute the most severely ill and suicidal patients, are not eligible to participate in head-to-head randomized controlled trials. Large-scale studies are required to investigate the anti-suicidal effects of ECT vs psychopharmacotherapy. METHODS: A nationwide retrospective cohort study design was used...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29225345/common-variants-at-2q11-2-8q21-3-and-11q13-2-are-associated-with-major-mood-disorders
#3
Xiao Xiao, Lu Wang, Chuang Wang, Ti-Fei Yuan, Dongsheng Zhou, Fanfan Zheng, Lingyi Li, Maria Grigoroiu-Serbanescu, Masashi Ikeda, Nakao Iwata, Atsushi Takahashi, Yoichiro Kamatani, Michiaki Kubo, Martin Preisig, Zoltán Kutalik, Enrique Castelao, Giorgio Pistis, Najaf Amin, Cornelia M van Duijn, Andreas J Forstner, Jana Strohmaier, Julian Hecker, Thomas G Schulze, Bertram Müller-Myhsok, Andreas Reif, Philip B Mitchell, Nicholas G Martin, Peter R Schofield, Sven Cichon, Markus M Nöthen, Hong Chang, Xiong-Jian Luo, Yiru Fang, Yong-Gang Yao, Chen Zhang, Marcella Rietschel, Ming Li
Bipolar disorder (BPD) and major depressive disorder (MDD) are primary major mood disorders. Recent studies suggest that they share certain psychopathological features and common risk genes, but unraveling the full genetic architecture underlying the risk of major mood disorders remains an important scientific task. The public genome-wide association study (GWAS) data sets offer the opportunity to examine this topic by utilizing large amounts of combined genetic data, which should ultimately allow a better understanding of the onset and development of these illnesses...
December 11, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29223913/prevalence-of-childhood-trauma-and-correlations-between-childhood-trauma-suicidal-ideation-and-social-support-in-patients-with-depression-bipolar-disorder-and-schizophrenia-in-southern-china
#4
Peng Xie, Kai Wu, Yingjun Zheng, Yangbo Guo, Yuling Yang, Jianfei He, Yi Ding, Hongjun Peng
BACKGROUND: Childhood trauma has long-term adverse effects on physical and psychological health. Previous studies demonstrated that suicide and mental disorders were related to childhood trauma. In China, there is insufficient research available on childhood trauma in patients with mental disorders. METHODS: Outpatients were recruited from a psychiatric hospital in southern China, and controls were recruited from local communities. The demographic questionnaire, the Childhood Trauma Questionnaire-Short Form (CTQ-SF), and the Social Support Rating Scale (SSRS) were completed by all participants, and the Self-rating Idea of Suicide Scale (SIOSS) were completed only by patients...
November 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29222850/exploratory-study-of-imagery-rescripting-without-focusing-on-early-traumatic-memories-for-major-depressive-disorder
#5
Fuminori Yamada, Yoichi Hiramatsu, Tomokazu Murata, Yoichi Seki, Mizue Yokoo, Remi Noguchi, Takayuki Shibuya, Mari Tanaka, Rieko Takanashi, Eiji Shimizu
BACKGROUND: Mental imagery has a more powerful impact on our emotions than thinking in words about the same material. Treating intrusive images with imagery rescripting (IR) has been reported for various disorders, including post-traumatic stress disorder, social anxiety disorder, and bipolar disorder. There has been less research about IR as a major depressive disorder (MDD). AIMS: We examined whether IR without focusing on early traumatic memories is effective in MDD...
December 9, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29221697/prevalence-of-mental-health-disorders-in-elderly-u-s-military-veterans-a-meta-analysis-and-systematic-review
#6
Victoria Williamson, Sharon A M Stevelink, Karla Greenberg, Neil Greenberg
OBJECTIVE: Older veterans may be vulnerable to mental health problems. Meta-analytic and systematic review methods sought to determine the prevalence rate of mental health disorders in older military veterans (≥65 years). METHODS: Eleven studies were eligible, and meta-analyses of veteran depression, substance abuse, post-traumatic stress disorder (PTSD), anxiety, dementia, bipolar disorder, and schizophrenia were conducted. RESULTS: Although conducted exclusively with U...
November 8, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29220680/adherence-to-physical-activity-recommendations-and-physical-and-mental-health-risk-in-people-with-severe-mental-illness-in-uganda
#7
Davy Vancampfort, Michel Probst, David Basangwa, Marc De Hert, Inez Myin-Germeys, Ruud van Winkel, Philip B Ward, Simon Rosenbaum, James Mugisha
This study investigated cardio-metabolic risk factors among patients with severe mental illness who do or do not meet the recommendations of 150min per week of physical activity. A secondary aim was to assess whether those that do meet the recommendations report lower levels of mental health symptoms. 107 (60♀) Ugandan in- and outpatients (mean age=34.4 ± 9.7 years) with severe mental illness (depression=7, bipolar disorder=55, schizophrenia=45) completed the Physical Activity Vital Sign (PAVS) method and Brief Symptoms Inventory -18...
November 29, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29217725/atrial-fibrillation-in-patients-with-severe-mental-disorders-and-the-risk-of-stroke-fatal-thromboembolic-events-and-bleeding-a-nationwide-cohort-study
#8
Mette Søgaard, Flemming Skjøth, Jette Nordstrøm Kjældgaard, Torben Bjerregaard Larsen, Søren Pihlkjær Hjortshøj, Sam Riahi
OBJECTIVES: Outcomes of atrial fibrillation (AF) in patients with severe mental disorders are largely unknown. We compared rates of stroke, fatal thromboembolic events and bleeding in patients with AF with and without mental disorders. DESIGN: Nationwide registry-based cohort study. SETTING: Denmark (population 5.6 million), 2000-2015. PARTICIPANTS: Patients with AF with schizophrenia (n=534), severe depression (n=400) or bipolar disease (n=569) matched 1:5 on age, sex and calendar time to patients with AF without mental disorders...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29216484/beliefs-about-the-causes-of-and-treatments-for-depression-and-bipolar-disorder-among-south-koreans
#9
Subin Park, Hyesue Jang, Adrian Furnham, Mina Jeon, Se Jin Park
Public beliefs about psychiatric disorders are important for understanding help-seeking behaviours. We investigated factors that affect South Koreans' beliefs about the causes and treatment of depression and bipolar disorder. We recruited 654 participants aged 15-54 years using an online panel survey. Participants completed two questionnaires: 34 possible causes of and 33 possible treatments for depression and bipolar disorder. For both disorders, the questionnaires about causes revealed four factors: social-environmental, God/fate, heath/lifestyle, and biological; the questionnaires about treatments revealed five factors: self-help/stress management, physical treatment/health management, seeking mental health services, religious help, and resting...
November 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29212563/clinically-relevant-and-simple-immune-system-measure-is-related-to-symptom-burden-in-bipolar-disorder
#10
Ole Köhler-Forsberg, Louisa Sylvia, Thilo Deckersbach, Michael Joshua Ostacher, Melvin McInnis, Dan Iosifescu, Charles Bowden, Susan McElroy, Joseph Calabrese, Michael Thase, Richard Charles Shelton, Mauricio Tohen, James Kocsis, Edward Friedman, Terence Ketter, Andrew Alan Nierenberg
OBJECTIVE: Immunological theories, particularly the sickness syndrome theory, may explain psychopathology in mood disorders. However, no clinical trials have investigated the association between overall immune system markers with a wide range of specific symptoms including potential gender differences. METHODS: We included two similar clinical trials, the lithium treatment moderate-dose use study and clinical and health outcomes initiatives in comparative effectiveness for bipolar disorder study, enrolling 765 participants with bipolar disorder...
December 7, 2017: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/29211117/adaptation-and-validation-of-the-melbourne-decision-making-questionnaire-to-brazilian-portuguese
#11
Charles Cotrena, Laura Damiani Branco, Rochele Paz Fonseca
INTRODUCTION: Decision making (DM) is among the most important abilities for everyday functioning. However, the most widely used measures of DM come from behavioral paradigms, whose ecological validity and standalone use has been criticized in the literature. Though these issues could be addressed by the use of DM questionnaires as a complementary assessment method, no such instruments have been validated for use in Brazilian Portuguese. Therefore, the aim of this study was to conduct the translation and validation of the Melbourne Decision Making Questionnaire (MDMQ) for use in a Brazilian population...
December 4, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/29209876/mentalization-deficit-in-bipolar-patients-during-an-acute-depressive-and-manic-episode-association-with-cognitive-functions
#12
Anna Bodnar, Janusz K Rybakowski
BACKGROUND: A number of studies in bipolar patients have shown a deficit in mentalization (theory of mind), one of the main aspects of social cognition. The aim of current study was to assess both cognitive and affective mentalization in well-defined groups of depressed and manic bipolar patients, compared to healthy control subjects, using a battery of tests measuring mentalization processes. The second aim was to investigate a possible relationship between cognitive and affective mentalization and cognitive functions in bipolar patients during a depressive and manic episode...
December 6, 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29207008/cannabis-use-and-hypomania-in-young-people-a-prospective-analysis
#13
Steven Marwaha, Catherine Winsper, Paul Bebbington, Daniel Smith
Background: Cannabis use in young people is common and associated with psychiatric disorders. However, the prospective link between cannabis use and bipolar disorder symptoms has rarely been investigated. The study hypothesis was that adolescent cannabis use is associated with hypomania in early adulthood via several potential etiological pathways. Methods: Data were used from the Avon Longitudinal Study of Parents and Children, a UK birth cohort study. The prospective link between cannabis use at age 17 and hypomania at age 22-23 years was tested using regression analysis, adjusted for gender, early environmental risk factors, alcohol and drug use, and depression and psychotic symptoms at age 18 years...
November 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29202177/distinctive-neuroanatomical-substrates-for-depression-in-bipolar-disorder-versus-major-depressive-disorder
#14
Koji Matsuo, Kenichiro Harada, Yusuke Fujita, Yasumasa Okamoto, Miho Ota, Hisashi Narita, Benson Mwangi, Carlos A Gutierrez, Go Okada, Masahiro Takamura, Hirotaka Yamagata, Ichiro Kusumi, Hiroshi Kunugi, Takeshi Inoue, Jair C Soares, Shigeto Yamawaki, Yoshifumi Watanabe
No neuroanatomical substrates for distinguishing between depression of bipolar disorder (dBD) and major depressive disorder (dMDD) are currently known. The aim of the current multicenter study was to identify neuroanatomical patterns distinct to depressed patients with the two disorders. Further analysis was conducted on an independent sample to enable generalization of results. We directly compared MR images of these subjects using voxel-based morphometry (VBM) and a support vector machine (SVM) algorithm using 1531 participants...
November 30, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29200575/are-we-overdiagnosing-bipolar-disorder
#15
M S Reddy, Starlin M Vijay, Swetha Reddy
Bipolar disorder (BD) is an established diagnostic entity used by clinicians for over a century. It is distinguished by the distinct manic and depressive episodes with interepisode euthymia. It has an illness course where both recovery and recurrences are a rule and has a good long-term prognosis, as reported earlier by Emil Kraeplin. There is an opinion in the current literature that BD is often underdiagnosed as unipolar depression, and based on that opinion, spectrum concept was introduced. Here, we present 5 cases to highlight that overdiagnosis of BD is also not infrequent and we discuss its reasons and therapeutic implications...
September 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29199810/ketamine-as-treatment-for-depression
#16
Tero Taiminen
Ketamine infusions administered intravenously 1 to 3 times per week are the quickest and most effective treatment for depression. Short-course ketamine medication is established treatment both for unipolar depression and depressive episodes of bipolar affective disorder. Ketamine is suitable for initiating the treatment for treatment-resistant depression, alleviation of suicidal tendencies, and treatment of depressive patients suffering from simultaneous pain. The safety of prolonged treatment with ketamine is not known to sufficient degree...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29199760/effectivity-and-cost-effectivity-of-the-maintenance-electroconvulsive-therapy-a-mirror-naturalistic-analysis
#17
Albert Cosculluela, Jesús Cobo, Erika Martínez-Amorós, Montse Paños, Angel M Santiago, Sara Crivillés, María Camposo, Joan C Oliva, Albert Granero, Diego J Palao
INTRODUCTION: Maintenance Electroconvulsive Therapy (mECT) is a biological long-term treatment in which patients receive ECT on periods from 2 to 4 weeks, during a variable period of time, usually for more than 6 months. Recent studies showed the efficacy of mECT in prevention of relapse and recurrences. Our study wants to demostrate the effectivity and cost-effectivity of this therapy in the naturalistic conditions of our area. METHODOLOGY: HASH(0x43253c0) DESIGN: Retrospective longitudinal study, with mirror analysis in naturalistic conditions...
November 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29197196/analysis-of-the-prevalence-of-mental-disorders-in-psoriasis-the-relevance-of-psychiatric-assessment-in-dermatology
#18
Bárbara Roque Ferreira, José Luís Pio-Abreu, José Pedro Reis, Américo Figueiredo
BACKGROUND: The boundary between Dermatology and Psychiatry has increasing recognition. Psoriasis is a common psychophysiological skin disease with a major impact on patient's quality of life and a paradigmatic example of a pathology in that boundary. Studies are needed to exactly point out the prevalence of specific psychopathology and mental disorders associated with psoriasis. This work intends to analyse the prevalence of psychopathology and psychiatric comorbidities in patients with psoriasis...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29197116/biological-systems-are-a-common-link-between-alcohol-use-disorder-and-co-occurring-psychiatric-and-medical-conditions
#19
Sarah L Hagerty, Jarrod M Ellingson, Kent E Hutchison
Alcohol use disorder (AUD) commonly co-occurs with other psychiatric and medical conditions. For example, individuals with AUD are nearly four-times more likely to have Major Depressive Disorder (MDD), six-times more likely to have Bipolar Disorder, and twice as likely to be diagnosed with Post Traumatic Stress Disorder (PTSD) (Kessler et al., 2003). Additionally, medical conditions are commonly comorbid with AUD, and heavy, chronic alcohol use is a risk factor for a host of wide-ranging medical disorders (Rehm et al...
December 2, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29196072/social-involvement-issues-in-patients-with-becker-muscular-dystrophy-a-questionnaire-survey-of-subjects-from-a-patient-registry
#20
Madoka Mori-Yoshimura, Yukio Mizuno, Sumiko Yoshida, Narihiro Minami, Naohiro Yonemoto, Fumi Takeuchi, Ichizo Nishino, Miho Murata, Shin'ichi Takeda, Yuji Takahashi, En Kimura
BACKGROUND: Little is known about the relationship between Becker Muscular Dystrophy (BMD) and developmental problems, school life, employment, and mental problems. We aimed to clarify whether BMD is a risk factor for developmental disorders, problematic behavior, psychiatric diseases, and other social difficulties in school life and employment. METHODS: Adults with genetically or immunohistochemically confirmed BMD from the Registry of Muscular Dystrophy in Japan (REMUDY) were asked to complete a questionnaire regarding patient history, school life, employment, and mental problems...
November 29, 2017: Brain & Development
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