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https://www.readbyqxmd.com/read/28918450/clinical-utility-of-the-asdas-index-in-comparison-with-basdai-in-patients-with-ankylosing-spondylitis-axis-study
#1
Agustí Sellas I Fernandez, Xavier Juanola Roura, Alberto Alonso Ruiz, José Rosas, Julio Medina Luezas, Eduardo Collantes Estevez, Miguel Ángel Abad Hernández, Virginia Carrasco Benitez, Cesar Fisac
The objective of the study was to study the clinical utility of the Ankylosing Spondylitis Disease Activity Score (ASDAS) for the assessment of disease activity in ankylosing spondylitis (AS) patients, compared to the Bath Ankylosing Spondylitis Activity Index (BASDAI). This was a prospective longitudinal observational study in patients with AS (NY-modified criteria) from 23 Spanish centers. Physical and analytical data; global, lumbar, and nocturnal pain; ASDAS, BASDAI and minimally acceptable clinical status (PASS) were collected...
September 16, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28898946/towards-the-understanding-of-antibiotic-occurrence-and-transport-in-groundwater-findings-from-the-baix-fluvi%C3%A3-alluvial-aquifer-ne-catalonia-spain
#2
M Boy-Roura, J Mas-Pla, M Petrovic, M Gros, D Soler, D Brusi, A Menció
Antibiotics are an increasing focus of interest due to their high detection frequency in the environment. However, their presence in water bodies is not regulated by environmental policies. This field study investigates, for the first time, the occurrence, behavior and fate of a selection of 53 antibiotics, including up to 10 chemical groups, in an alluvial aquifer originated from manure application in an agricultural region using hydrogeological, hydrochemical and isotopic approaches. Up to 11 antibiotics were found in groundwater corresponding to 4 different chemical groups: fluoroquinolones, macrolides, quinolones and sulfonamides...
September 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28882616/screening-of-inflammatory-bowel-disease-and-spondyloarthritis-for-referring-patients-between-rheumatology-and-gastroenterology
#3
Jesús Sanz Sanz, Xavier Juanola Roura, Daniel Seoane-Mato, Miguel Montoro, Fernando Gomollón
OBJECTIVE: To define clinical screening criteria for spondyloarthritis (SpA) in patients with inflammatory bowel disease (IBD) and vice versa, which can be used as a reference for referring them to the rheumatology or gastroenterology service. METHOD: Systematic literature review and a two-round Delphi method. The scientific committee and the expert panel were comprised of 2 rheumatologists and 2 gastroenterologists, and 7 rheumatologists and 7 gastroenterologists, respectively...
September 4, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28870640/ivus-findings-in-late-and-very-late-stent-thrombosis-a-comparison-between-bare-metal-and-drug-eluting-stents
#4
Lara Fuentes, Josep Gómez-Lara, Neus Salvatella, Nieves Gonzalo, Felipe Hernández-Hernández, Eduard Fernández-Nofrerias, Ángel Sánchez-Recalde, Fernando Alfonso, Rafael Romaguera, José Luis Ferreiro, Gerard Roura, Luis Teruel, Montserrat Gracida, Ana Lucrecia Marcano, Joan-Antoni Gómez-Hospital, Ángel Cequier
INTRODUCTION AND OBJECTIVES: Stent thrombosis (ST) is a life-threatening complication after stent implantation. Intravascular ultrasound is able to discern most causes of ST. The aim of this study was to compare intravascular ultrasound findings between bare-metal stents (BMS) and drug-eluting stents (DES) in patients with late (31 days to 1 year) or very late ST (> 1 year). METHODS: Of 250 consecutive patients with late or very late ST in 7 Spanish institutions, 114 patients (45...
September 1, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28863429/biotherapies-and-biomarkers-for-cardiovascular-diseases-a-15-year-journey-at-the-icrec-heart-failure-and-cardiac-regeneration-research-laboratory-in-barcelona-spain
#5
Santiago Roura, Carolina Gálvez-Montón, Josep Lupón, Antoni Bayes-Genis
No abstract text is available yet for this article.
June 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28860996/prey-capture-ingestion-and-digestion-dynamics-of-octopus-vulgaris-paralarvae-fed-live-zooplankton
#6
Manuel Nande, Pablo Presa, Álvaro Roura, Paul L R Andrews, Montse Pérez
Octopus vulgaris is a species of great interest in research areas such as neurobiology, ethology, and ecology but also a candidate species for aquaculture as a food resource and for alleviating the fishing pressure on its wild populations. This study aimed to characterize the predatory behavior of O. vulgaris paralarvae and to quantify their digestive activity. Those processes were affordable using the video-recording analysis of 3 days post-hatching (dph), mantle-transparent paralarvae feeding on 18 types of live zooplanktonic prey...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28833875/characterization-of-phenolic-compounds-in-green-and-red-oak-leaf-lettuce-cultivars-by-uhplc-dad-esi-qtof-ms-using-ms-e-scan-mode
#7
Gabriela E Viacava, Sara I Roura, Luis A Berrueta, Carmen Iriondo, Blanca Gallo, Rosa M Alonso-Salces
Lettuce (Lactuca sativa) is one of the most popular leafy vegetables in the world and constitutes a major dietary source of phenolic compounds with health promoting properties. In particular, the demand for green and red oak-leaf lettuces have considerably increased in the last years but few data on their polyphenol composition is available. Moreover, the utilization of analytical edge technology can provide new structural information and allow the identification of unknown polyphenols. In the present study the phenolic profiles of green and red oak-leaf lettuce cultivars were exhaustively characterized by ultrahigh performance liquid chromatography (UHPLC) coupled online to diode array detection (DAD), electrospray ionization (ESI) and quadrupole time-of-flight mass spectrometry (QToF/MS), using the MS(E) instrument acquisition mode for recording simultaneously exact masses of precursor and fragment ions...
August 22, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28789915/association-of-general-and-abdominal-obesity-with-hypertension-dyslipidemia-and-prediabetes-in-the-predaps-study
#8
F Javier Sangrós, Jesús Torrecilla, Carolina Giráldez-García, Lourdes Carrillo, José Mancera, Teresa Mur, Josep Franch, Javier Díez, Albert Goday, Rosario Serrano, F Javier García-Soidán, Gabriel Cuatrecasas, Dimas Igual, Ana Moreno, J Manuel Millaruelo, Francisco Carramiñana, Manuel Antonio Ruiz, Francisco Carlos Pérez, Yon Iriarte, Ángela Lorenzo, María González, Beatriz Álvarez, Lourdes Barutell, M Soledad Mayayo, Mercedes Del Castillo, Emma Navarro, Fernando Malo, Ainhoa Cambra, Riánsares López, M Ángel Gutiérrez, Luisa Gutiérrez, Carmen Boente, J Javier Mediavilla, Luis Prieto, Luis Mendo, M José Mansilla, Francisco Javier Ortega, Antonia Borras, L Gabriel Sánchez, J Carlos Obaya, Margarita Alonso, Francisco García, Ángela Trinidad Gutiérrez, Ana M Hernández, Dulce Suárez, J Carlos Álvarez, Isabel Sáenz, F Javier Martínez, Ana Casorrán, Jazmín Ripoll, Alejandro Salanova, M Teresa Marín, Félix Gutiérrez, Jaime Innerárity, M Del Mar Álvarez, Sara Artola, M Jesús Bedoya, Santiago Poveda, Fernando Álvarez, M Jesús Brito, Rosario Iglesias, Francisca Paniagua, Pedro Nogales, Ángel Gómez, José Félix Rubio, M Carmen Durán, Julio Sagredo, M Teresa Gijón, M Ángeles Rollán, Pedro P Pérez, Javier Gamarra, Francisco Carbonell, Luis García-Giralda, J Joaquín Antón, Manuel de la Flor, Rosario Martínez, José Luis Pardo, Antonio Ruiz, Raquel Plana, Ramón Macía, Mercè Villaró, Carmen Babace, José Luis Torres, Concepción Blanco, Ángeles Jurado, José Luis Martín, Jorge Navarro, Gloria Sanz, Rafael Colas, Blanca Cordero, Cristina de Castro, Mercedes Ibáñez, Alicia Monzón, Nuria Porta, María Del Carmen Gómez, Rafael Llanes, J José Rodríguez, Esteban Granero, Manuel Sánchez, Juan Martínez, Patxi Ezkurra, Luis Ávila, Carlos de la Sen, Antonio Rodríguez, Pilar Buil, Paula Gabriel, Pilar Roura, Eduard Tarragó, Xavier Mundet, Remei Bosch, J Carles González, M Isabel Bobé, Manel Mata, Irene Ruiz, Flora López, Marti Birules, Oriol Armengol, Rosa Mar de Miguel, Laura Romera, Belén Benito, Neus Piulats, Beatriz Bilbeny, J José Cabré, Xavier Cos, Ramón Pujol, Mateu Seguí, Carmen Losada, A María de Santiago, Pedro Muñoz, Enrique Regidor
INTRODUCTION AND OBJECTIVES: Some anthropometric measurements show a greater capacity than others to identify the presence of cardiovascular risk factors. This study estimated the magnitude of the association of different anthropometric indicators of obesity with hypertension, dyslipidemia, and prediabetes (altered fasting plasma glucose and/or glycosylated hemoglobin). METHODS: Cross-sectional analysis of information collected from 2022 participants in the PREDAPS study (baseline phase)...
August 5, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28769811/feeding-relationship-between-octopus-vulgaris-cuvier-1797-early-life-cycle-stages-and-their-prey-in-the-western-iberian-upwelling-system-correlation-of-reciprocal-lipid-and-fatty-acid-contents
#9
Sílvia Lourenço, Álvaro Roura, María-José Fernández-Reiriz, Luís Narciso, Ángel F González
Under the influence of the Western Iberian upwelling system, the Iberian Atlantic coast holds important hatcheries and recruitment areas for Octopus vulgaris. Recently identified as an octopus hatchery, the Ría de Vigo harbors an important mesozooplankton community that supports O. vulgaris paralarvae during the first days of their planktonic stage. This study represents a preliminary approach to determine the nutritional link between wild O. vulgaris hatchlings, paralarvae and their zooplankton prey in the Ría de Vigo, by analyzing their lipid class content and fatty acid profiles...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28739838/unravelling-migrants-health-paradoxes-a-transdisciplinary-research-agenda
#10
REVIEW
Maria Roura
The Social Determinants of Health literature has consistently found that a higher socioeconomic status is associated with better health outcomes even after adjusting for traditional risk factors. However, research findings in the field of Migrants' Health suggest that the socioeconomic/health gradient does not always behave as expected for migrants and their descendants. The mismatch of findings in these two long-standing parallel research traditions is exemplified by frequent reports of paradoxical findings in the scientific literature: the healthy migrant paradox, the ethnic density paradox and the diminishing returns paradox...
July 24, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28734501/-idiopathic-normal-pressure-hydrocephalus-high-incidence-in-people-over-80-years-of-age
#11
Josep Maria Aragonès, Jacint Altimiras, Francisco Alonso, Pere Roura, Sebastián Alfonso, Lorena Bajo
INTRODUCTION: Idiopathic normal pressure hydrocephalus is usually observed in adults over 60 years of age. The highest incidence of cases is between 70 and 80 years-old, and it could be under-diagnosed in over 80 year-olds. OBJECTIVE: A description is presented on the overall incidence and age group incidence, the delay in the diagnosis, and main outcomes. PATIENTS AND METHODS: A descriptive study was performed on patients with idiopathic normal pressure hydrocephalus, in the population of Osona County during the years 2010-2015...
July 19, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28703578/detection-of-a-subset-of-posttranscriptional-transfer-rna-modifications-in-vivo-with-a-restriction-fragment-length-polymorphism-based-method
#12
Thomas F Wulff, Rafael J Argüello, Marc Molina Jordàn, Helena Roura Frigolé, Glenn Hauquier, Liudmila Filonava, Noelia Camacho, Evelina Gatti, Philippe Pierre, Lluís Ribas de Pouplana, Adrian G Torres
Transfer RNAs (tRNAs) are among the most heavily modified RNA species. Posttranscriptional tRNA modifications (ptRMs) play fundamental roles in modulating tRNA structure and function and are being increasingly linked to human physiology and disease. Detection of ptRMs is often challenging, expensive, and laborious. Restriction fragment length polymorphism (RFLP) analyses study the patterns of DNA cleavage after restriction enzyme treatment and have been used for the qualitative detection of modified bases on mRNAs...
August 8, 2017: Biochemistry
https://www.readbyqxmd.com/read/28699384/preclinical-safety-evaluation-of-allogeneic-ips-cell-based-therapy-in-a-swine-model-of-myocardial-infarction
#13
Carolina Gálvez-Montón, Carolina Soler-Botija, Oriol Iborra-Egea, Idoia Diaz-Guemes, Mercè Martí, Olalla Iglesias-Garcia, Cristina Prat-Vidal, Verónica Crisóstomo, Aida Llucià-Valldeperas, Isaac Perea-Gil, Santiago Roura, Francisco Miguel Sanchez Margallo, Ángel Raya, Antoni Bayés-Genís
The combination of biomatrices and induced pluripotent stem cell (iPSC) derivatives to aid repair and myocardial scar formation may soon become a reality for cardiac regenerative medicine. However, the tumor risk associated to residual undifferentiated cells remains an important safety concern of iPSC-based therapies. This concern is not satisfactorily addressed in xenotransplantation, which require immune suppression of the transplanted animal. Here, we assessed the safety of transplanting undifferentiated iPSC in an allogeneic setting...
July 12, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28679464/linoleic-la-and-linolenic-ala-acid-concentrations-in-follicular-fluid-of-prepubertal-goats-and-their-effect-on-oocyte-in-vitro-maturation-and-embryo-development
#14
Montserrat Roura, María G Catalá, Sandra Soto-Heras, Sondes Hammami, Dolors Izquierdo, Ali Fouladi-Nashta, Maria-Teresa Paramio
In this study we assessed the concentration of linoleic acid (LA) and linolenic acid (ALA) in follicular fluid of prepubertal goats according to follicle size (<3mm or ≥3mm) by gas chromatography and tested the addition of different LA and ALA (LA:ALA) concentration ratios (50:50, 100:50 and 200:50µM) to the IVM medium on embryo development, mitochondrial activity, ATP concentration and relative gene expression (RPL19, ribosomal protein L19; SLC2A1, facilitated glucose transporter 1; ATF4, activating transcription factor 4; GPX1, glutathione peroxidase 1; HSPA5, heat-shock protein family A 70 kDa; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; DNMT1, DNA methyltransferase 1; GCLC, glutamate-cysteine ligase catalytic subunit; SOD1, superoxide dismutase 1)...
July 6, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28666409/end-stage-renal-disease-in-french-guiana-data-from-r-e-i-n-registry-south-american-or-french
#15
Dévi Rita Rochemont, Mohamed Meddeb, Raoul Roura, Cécile Couchoud, Mathieu Nacher, Célia Basurko
BACKGROUND: End-Stage renal disease (ESRD) causes considerable morbidity and mortality, and significantly alters patients' quality of life. There are very few published data on this problem in the French Overseas territories. The development of a registry on end stage renal disease in French Guiana in 2011 allowed to describe the magnitude of this problem in the region for the first time. METHODS: Using data from the French Renal Epidemiology and Information Network registry (R...
June 30, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28649439/mechanisms-of-action-of-sacubitril-valsartan-on-cardiac-remodeling-a-systems-biology-approach
#16
Oriol Iborra-Egea, Carolina Gálvez-Montón, Santiago Roura, Isaac Perea-Gil, Cristina Prat-Vidal, Carolina Soler-Botija, Antoni Bayes-Genis
Sacubitril/Valsartan, proved superiority over other conventional heart failure management treatments, but its mechanisms of action remains obscure. In this study, we sought to explore the mechanistic details for Sacubitril/Valsartan in heart failure and post-myocardial infarction remodeling, using an in silico, systems biology approach. Myocardial transcriptome obtained in response to myocardial infarction in swine was analyzed to address post-infarction ventricular remodeling. Swine transcriptome hits were mapped to their human equivalents using Reciprocal Best (blast) Hits, Gene Name Correspondence, and InParanoid database...
2017: NPJ Systems Biology and Applications
https://www.readbyqxmd.com/read/28625274/beneficial-effects-of-melatonin-on-in-vitro-embryo-production-from-juvenile-goat-oocytes
#17
Sandra Soto-Heras, Montserrat Roura, Maria G Catalá, Irene Menéndez-Blanco, Dolors Izquierdo, Ali A Fouladi-Nashta, Maria T Paramio
Melatonin is a universal antioxidant that improves in vitro embryo production in several species. The aims of this study were to determine the melatonin concentration in the ovarian follicular fluid (FF) of juvenile goats and the effect of melatonin during in vitro maturation (IVM) on embryo development. The FF melatonin concentration was 0.57--1.07×10-9 M, increasing with follicular diameter. Oocytes were matured, fertilised and cultured under conventional conditions. Blastocyst development, embryo quality and levels of reactive oxygen species (ROS) and reduced glutathione were assessed...
June 19, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28620315/you-are-what-you-eat-a-genomic-analysis-of-the-gut-microbiome-of-captive-and-wild-octopus-vulgaris-paralarvae-and-their-zooplankton-prey
#18
Álvaro Roura, Stephen R Doyle, Manuel Nande, Jan M Strugnell
The common octopus (Octopus vulgaris) is an attractive species for aquaculture, however, several challenges inhibit sustainable commercial production. Little is known about the early paralarval stages in the wild, including diet and intestinal microbiota, which likely play a significant role in development and vitality of this important life stage. High throughput sequencing was used to characterize the gastrointestinal microbiome of wild O. vulgaris paralarvae collected from two different upwelling regions off the coast of North West Spain (n = 41) and Morocco (n = 35)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28596735/diet-composition-and-variability-of-wild-octopus-vulgaris-and-alloteuthis-media-cephalopoda-paralarvae-a-metagenomic-approach
#19
Lorena Olmos-Pérez, Álvaro Roura, Graham J Pierce, Stéphane Boyer, Ángel F González
The high mortality of cephalopod early stages is the main bottleneck to grow them from paralarvae to adults in culture conditions, probably because the inadequacy of the diet that results in malnutrition. Since visual analysis of digestive tract contents of paralarvae provides little evidence of diet composition, the use of molecular tools, particularly next generation sequencing (NGS) platforms, offers an alternative to understand prey preferences and nutrient requirements of wild paralarvae. In this work, we aimed to determine the diet of paralarvae of the loliginid squid Alloteuthis media and to enhance the knowledge of the diet of recently hatched Octopus vulgaris paralarvae collected in different areas and seasons in an upwelling area (NW Spain)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28557183/extracellular-vesicles-do-not-contribute-to-higher-circulating-levels-of-soluble-lrp1-in-idiopathic-dilated-cardiomyopathy
#20
Santiago Roura, Carolina Gálvez-Montón, David de Gonzalo-Calvo, Ana Gámez Valero, Paloma Gastelurrutia, Elena Revuelta-López, Cristina Prat-Vidal, Carolina Soler-Botija, Aida Llucià-Valldeperas, Isaac Perea-Gil, Oriol Iborra-Egea, Francesc E Borràs, Josep Lupón, Vicenta Llorente-Cortés, Antoni Bayes-Genis
Idiopathic dilated cardiomyopathy (IDCM) is a frequent cause of heart transplantation. Potentially valuable blood markers are being sought, and low-density lipoprotein receptor-related protein 1 (LRP1) has been linked to the underlying molecular basis of the disease. This study compared circulating levels of soluble LRP1 (sLRP1) in IDCM patients and healthy controls and elucidated whether sLRP1 is exported out of the myocardium through extracellular vesicles (EVs) to gain a better understanding of the pathogenesis of the disease...
May 29, 2017: Journal of Cellular and Molecular Medicine
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