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Magnesium supplementation

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https://www.readbyqxmd.com/read/28074329/dietary-adequacy-of-egyptian-children-with-autism-spectrum-disorder-compared-to-healthy-developing-children
#1
Nagwa A Meguid, Mona Anwar, Geir Bjørklund, Adel Hashish, Salvatore Chirumbolo, Maha Hemimi, Eman Sultan
Although the etiology and pathology of autism spectrum disorder (ASD) is still poorly understood, a number of environmental, anthropological, neurobiological and genetic factors have been related to the pathophysiology of ASD, even the impact of oxidative stress response related to the environment and nutrition intake. Usual recommended dietary habits are based on the combination of behavioral and dietary or nutraceutical interventions together with pharmacotherapy. Investigations about a reliable relationship between diet and ASD are still lacking...
January 10, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28073210/the-importance-of-citrates-in-treatment-and-prophylaxis-of-calcium-oxalate-urinary-stones
#2
Michele Barbera, Andreas Tsirgiotis, Mauro Barbera, Quintino Paola
About 10% of the people is the subject of an episode of kidney stones during their lifetime, about 70% of these people undergoes relapses. About 80% of the urinary stones contains calcium, of wich 80% is formed of calcium oxalate, in pure form or associated with calcium phosphate. Therefore we can saythat in most cases (about 65%) the urinary stones are composedof calcium oxalate. Use of supplements of potassium citrate and magnesium citrate can help in the prevention of kidney stones of calcium oxalate, but mostly they can be used in the days before a shockwaves lithotripsy treatment to make the stones more fragile to the effect of the shock waves...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28070078/atr-ft-ir-and-nir-auto-correlation-spectroscopic-analysis-of-powder-blending-uniformity-of-low-content-magnesium-stearate-and-potato-starch
#3
Yusuke Hattori, Makoto Otsuka
Here, we report on near-infrared and ATR/FT-IR spectroscopic measurements of magnesium stearate and potato starch powder blends. In the pharmaceutical and food industries, magnesium stearate is commonly used as a supplement in powder blends or granules for the purpose of lubrication and to minimize aggregation and adherence. However, excessive blending of magnesium stearate (MgSt) may lead to unwanted effects, and more particularly during the manufacturing of products. Upon blending, the IR bands due to both CH symmetric and anti-symmetric stretching modes decreased and displayed a frequency shift to higher wavenumber as the blending duration increased...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/28062462/increasing-growth-yield-and-decreasing-acetylation-in-escherichia-coli-by-optimizing-the-carbon-to-magnesium-ratio-in-peptide-based-media
#4
David G Christensen, James S Orr, Christopher V Rao, Alan J Wolfe
: Complex media are routinely used to cultivate diverse bacteria. However, this complexity can obscure the factors that govern cell growth. While studying protein acetylation in buffered tryptone broth supplemented with glucose (TB7/glucose), we observed that Escherichia coli did not fully consume glucose prior to stationary phase. However, when we supplemented this medium with magnesium, the glucose was completely consumed during exponential growth with concomitant increases in cell number and biomass but reduced cell size...
January 6, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28056273/-study-on-the-contribution-rate-of-follow-up-formula-to-the-nutrient-intake-of-infants-and-young-children-aged-7-24-months-in-china
#5
H Z Li, H X Jia, D Liang, T T Deng, L T Niu, J H Han
Objective: To determine the contribution of follow-up formula (FUF) to the nutrient intake of 7-24-month-old infants and young children. Methods: The cluster random sampling method and the convenience sampling method were used in combination, and geographic and economic factors were taken into consideration. Four areas of China (Beijing, Hebei, Guangxi, Guangdong) were selected, with 120 infants chosen from each of these areas (half of which were 7-12 months old, and half were 13-24 months old). A dietary survey was completed by a continuous 24-hour weighing method over two days...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28053581/optimization-of-formulation-and-processing-of-moringa-oleifera-and-spirulina-complex-tablets
#6
Yi Zheng, Fan Zhu, Dan Lin, Jun Wu, Yichao Zhou, Bohn Mark
Objective: To prepare a more comprehensive nutrition, more balanced proportion of natural nutritional supplement tablets with Moringa oleifera leaves and spirulina the two nutrients which have complementary natural food ingredients. Method: On the basis of research M. oleifera leaves with spirulina nutrient composition was determined on M. oleifera leaves and spirulina ratio of raw materials, and the choice of microcrystalline cellulose, sodium salt of caboxy methyl cellulose(CMC),magnesium stearate excipient, through single factor and orthogonal experiment, selecting the best formula tablets prepared by powder direct compression technology, for preparation of M...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28039534/hypomagnesemia-and-increased-risk-of-new-onset-diabetes-mellitus-after-transplantation-in-pediatric-renal-transplant-recipients
#7
Wesley Hayes, Sheila Boyle, Adrian Carroll, Detlef Bockenhauer, Stephen D Marks
BACKGROUND: New-onset diabetes after transplantation (NODAT) is a significant co-morbidity following kidney transplantation. Lower post-transplant serum magnesium levels have been found to be an independent risk factor for NODAT in adult kidney transplant recipients. METHODS: We undertook a retrospective analysis of risk factors for NODAT in pediatric renal transplant recipients at our institution with the aim of determining if hypomagnesemia confers a significant risk of developing NODAT in this patient population...
December 30, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28033128/renal-function-of-cyclin-m2-mg2-transporter-maintains-blood-pressure
#8
Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki
OBJECTIVES: Epidemiological studies have shown that magnesium intake/excretion is inversely correlated with blood pressure (BP), and artificial supplementation of magnesium was able to prevent hypertension. However, there has been no molecular genetic study showing the importance of magnesium homeostasis in BP regulation. METHODS: We analyzed magnesium content and BP of mice lacking genes encoding cyclin M (CNNM) Mg transporter family proteins. RESULTS: Systemic heterozygotes and the kidney-specific homozygotes for Cnnm2-deficient alleles are both viable and show hypomagnesemia, indicating the important function of CNNM2 in maintaining magnesium homeostasis in the kidney...
December 28, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/28019093/creatine-and-creatine-forms-intended-for-sports-nutrition
#9
REVIEW
Susanne Andres, Rainer Ziegenhagen, Iris Trefflich, Sophie Pevny, Katharina Schultrich, Hans Braun, Wilhelm Schänzer, Karen Ildico Hirsch-Ernst, Bernd Schäfer, Alfonso Lampen
Creatine is a popular ergogenic supplement in sports nutrition. Yet, supplementation of creatine occasionally caused adverse effects such as gastrointestinal complaints, muscle cramps and an increase in body weight. Creatine monohydrate has already been evaluated by different competent authorities and several have come to the conclusion that a daily intake of 3 g creatine per person is unlikely to pose safety concerns, focusing on healthy adults with exclusion of pregnant and breastfeeding women. Possible vulnerable subgroups were also discussed in relation to the safety of creatine...
December 25, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28007671/magnesium-based-interventions-for-normal-kidney-function-and-chronic-kidney-disease
#10
Ziad A Massy, Ionut Nistor, Mugurel Apetrii, Vincent M Brandenburg, Jordi Bover, Pieter Evenepoel, David Goldsmith, Sandro Mazzaferro, Pablo Urena-Torres, Marc G Vervloet, Mario Cozzolino, Adrian Covic, On Behalf Of Ckd-Mbd Working Group Of Era-Edta
Magnesium (Mg) is one of the most important cations in the body, playing an essential role in biological systems as co-factor for more than 300 essential enzymatic reactions. In the general population, low levels of Mg are associated with a high risk of cardio-vascular disease (CVD). Despite the accumulating literature data, the effect of Mg administration on mortality in chronic kidney disease (CKD) patients has never been investigated as a primary end-point. We conducted a systematic search of studies assessing the benefits and harms of Mg in CKD (stages 1 to 5 and 5D), and considered all randomized controlled trials (RCTs) and quasi-RCTs evaluating Mg-based interventions in CKD...
December 22, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/28003083/gitelman-syndrome-consensus-and-guidance-from-a-kidney-disease-improving-global-outcomes-kdigo-controversies-conference
#11
Anne Blanchard, Detlef Bockenhauer, Davide Bolignano, Lorenzo A Calò, Etienne Cosyns, Olivier Devuyst, David H Ellison, Fiona E Karet Frankl, Nine V A M Knoers, Martin Konrad, Shih-Hua Lin, Rosa Vargas-Poussou
Gitelman syndrome (GS) is a rare, salt-losing tubulopathy characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. The disease is recessively inherited, caused by inactivating mutations in the SLC12A3 gene that encodes the thiazide-sensitive sodium-chloride cotransporter (NCC). GS is usually detected during adolescence or adulthood, either fortuitously or in association with mild or nonspecific symptoms or both. The disease is characterized by high phenotypic variability and a significant reduction in the quality of life, and it may be associated with severe manifestations...
January 2017: Kidney International
https://www.readbyqxmd.com/read/27997264/decrease-in-ionized-and-total-magnesium-blood-concentrations-in-endurance-athletes-following-an-exercise-bout-restores-within-hours-potential-consequences-for-monitoring-and-supplementation
#12
Rieneke Terink, Michael G J Balvers, Maria T Hopman, Renger F Witkamp, Marco Mensink, Jacqueline M T Klein Gunnewiek
Magnesium is essential for optimal sport performance, generating an interest to monitor its status in athletes. However, before measuring magnesium status in blood could become routine, more insight into its diurnal fluctuations and effects of exercise itself is necessary. Therefore, we measured the effect of an acute bout of exercise on ionized (iMg) and total plasma magnesium (tMg) in blood obtained from 18 healthy well-trained endurance athletes (age, 31.1 ± 8.1 yr.; VO2max, 50.9 ± 7.5 ml/kg/min) at multiple time points, and compared this with a resting situation...
December 20, 2016: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/27995107/evaluating-the-effectiveness-of-adding-magnesium-chloride-to-conventional-protocol-of-citrate-alkali-therapy-on-kidney-stone-size
#13
Hassan Niroomand, Amin Ziaee, Keivan Ziaee, Alaleh Gheissari
BACKGROUND: Potassium citrate (K-Cit) is one of the therapeutic solutions broadly used in patients with urolithiasis. However, recent studies have shown that it is not so effective. Therefore, the goal of our study was to evaluate the effect of a combination of K-Cit - MgCl2 oral supplements, on urinary stone size. MATERIALS AND METHODS: This study was performed on 70 asymptomatic urolithiasis cases. The supplements included K-Cit and magnesium chloride (MgCl2), purchased from (Merck Company, Germany)...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27991852/epithelial-magnesium-transport-by-trpm6-is-essential-for-prenatal-development-and-adult-survival
#14
Vladimir Chubanov, Silvia Ferioli, Annika Wisnowsky, David G Simmons, Christin Leitzinger, Claudia Einer, Wenke Jonas, Yuriy Shymkiv, Harald Bartsch, Attila Braun, Banu Akdogan, Lorenz Mittermeier, Ludmila Sytik, Friedrich Torben, Vindi Jurinovic, Emiel Pc van der Vorst, Christian Weber, Önder A Yildirim, Karl Sotlar, Annette Schürmann, Susanna Zierler, Hans Zischka, Alexey G Ryazanov, Thomas Gudermann
Mg(2+) regulates many physiological processes and signalling pathways. However, little is known about the mechanisms underlying the organismal balance of Mg(2+). Capitalizing on a set of newly generated mouse models, we provide an integrated mechanistic model of the regulation of organismal Mg(2+) balance during prenatal development and in adult mice by the ion channel TRPM6. We show that TRPM6 activity in the placenta and yolk sac is essential for embryonic development. In adult mice, TRPM6 is required in the intestine to maintain organismal Mg(2+) balance, but is dispensable in the kidney...
December 19, 2016: ELife
https://www.readbyqxmd.com/read/27990155/dietary-supplement-comprised-of-%C3%AE-carotene-vitamin-c-vitamin-e-and-magnesium-failure-to-prevent-music-induced-temporary-threshold-shift
#15
C G Le Prell, A Fulbright, C Spankovich, S K Griffiths, E Lobarinas, K C M Campbell, P J Antonelli, G E Green, K Guire, J M Miller
This study examined potential prevention of music-induced temporary threshold shift (TTS) in normal-hearing participants. A dietary supplement composed of β-carotene, vitamins C and E, and magnesium was assessed using a randomized, placebo-controlled, double-blind study design. Dosing began 3 days prior to the music exposure with the final dose consumed approximately 30-min pre-exposure. There were no group differences in post-exposure TTS or music-induced decreases in distortion product otoacoustic emission (DPOAE) amplitude...
May 2016: Audiology and Neurotology. Extra
https://www.readbyqxmd.com/read/27974309/analytical-ingredient-content-and-variability-of-adult-multivitamin-mineral-products-national-estimates-for-the-dietary-supplement-ingredient-database
#16
Karen W Andrews, Janet M Roseland, Pavel A Gusev, Joel Palachuvattil, Phuong T Dang, Sushma Savarala, Fei Han, Pamela R Pehrsson, Larry W Douglass, Johanna T Dwyer, Joseph M Betz, Leila G Saldanha, Regan L Bailey
BACKGROUND: Multivitamin/mineral products (MVMs) are the dietary supplements most commonly used by US adults. During manufacturing, some ingredients are added in amounts exceeding the label claims to compensate for expected losses during the shelf life. Establishing the health benefits and harms of MVMs requires accurate estimates of nutrient intake from MVMs based on measures of actual rather than labeled ingredient amounts. OBJECTIVES: Our goals were to determine relations between analytically measured and labeled ingredient content and to compare adult MVM composition with Recommended Dietary Allowances (RDAs) and Tolerable Upper Intake Levels...
December 14, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27966021/short-hydration-regimen-with-magnesium-supplementation-prevents-cisplatin-induced-nephrotoxicity-in-lung-cancer-a-retrospective-analysis
#17
Teppei Yamaguchi, Sakurako Uozu, Sumito Isogai, Masamichi Hayashi, Yasuhiro Goto, Toru Nakanishi, Kazuyoshi Imaizumi
PURPOSE: The purpose of this study was to evaluate renal function in lung cancer patients who were administered cisplatin with continuous higher-volume hydration (CH) or a short hydration (SH) regimen. METHODS: We retrospectively evaluated patients with lung cancer who were treated with chemotherapy regimens including >50 mg/m(2) of cisplatin between August 2007 and March 2015. Between August 2007 and December 2012, patients received a continuous higher-volume hydration regimen without magnesium (Mg) supplementation (CH group), and after May 2013, patients received a short hydration regimen with Mg supplementation (SH group)...
December 13, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27939858/a-quick-reference-on-magnesium
#18
REVIEW
Shane W Bateman
This article serves as a quick reference on the distribution, handling, and supplementation of magnesium. It also lists the manifestations and causes of magnesium deficit and provides criteria for the diagnosis of a magnesium deficit.
December 8, 2016: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/27933574/-long-term-hrv-analysis-shows-stress-reduction-by-magnesium-intake
#19
Elmar Wienecke, Claudia Nolden
BACKGROUND: Mental pressure and stress represent an ever-increasing socio-political challenge. The heart rate variability (HRV) measurement, which has its origin in the cardiac function diagnosis, gives information on the neurovegetative activity. A low HRV shows an imbalance of the sympathetic and parasympathetic efferents and thus is an indicator of stress. METHOD: A randomized, controlled, two-armed parallel study with 100 participants and a period of 90 days was performed...
December 2016: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/27929695/secondhand-smoke-exposure-illness-severity-and-resource-utilization-in-pediatric-emergency-department-patients-with-respiratory-illnesses
#20
Ashley L Merianos, Cinnamon A Dixon, E Melinda Mahabee-Gittens
OBJECTIVE: Hospital-based data reveal that children who have secondhand smoke exposure (SHSe) experience severe respiratory illnesses and greater resource utilization. Our objective was to assess the relationship between SHSe and illness severity/resource utilization among children presenting to the pediatric emergency department (PED) with three common respiratory conditions - asthma, bronchiolitis, and pneumonia. METHODS: A retrospective review of a yearlong consecutive sample of PED patients with SHSe status documentation and asthma, bronchiolitis, or pneumonia diagnoses was performed...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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