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Magnesium supplementation

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https://www.readbyqxmd.com/read/29319266/gitelman-syndrome-presenting-during-pregnancy-with-adverse-foetal-outcome
#1
N Nand, A R Deshmukh, R Mathur, V Chauhan, Brijlal
Gitelman syndrome (GS) is a rare autosomal recessive salt-losing tubulopathy. The incidence of Gitelman syndrome is 25 cases in 1 million among western population. This patient presented with loose stool, vomiting and sudden onset quadriparesis. Investigations revealed hypokalaemia, metabolic acidosis, hypomagnesaemia, hypocalciuria, hypermagnesuria. Symptoms and hypokalemia improved after starting oral magnesium and potassium supplements. But the patient again presented with symptomatic hypokalemia and delivered a still born foetus with hydrocephalus...
October 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29316608/vitamin-and-mineral-supplement-use-among-korean-adults-baseline-data-from-the-trace-element-study-of-korean-adults-in-yeungnam-area
#2
Minkyeong Kim, Yujin Lee, Kyong Park
Although dietary supplement use is believed to improve health status, the efficacy and safety of its use remains controversial. This study aimed to investigate the contribution of consumption of vitamin and mineral supplements (VMS) to the total micronutrient intake. Study participants (n = 586) were selected from the ongoing prospective cohort study of the Korean population, and baseline information on current use of dietary supplements, types of supplements, frequency of use, dosage, duration, and brand name was collected...
January 6, 2018: Nutrients
https://www.readbyqxmd.com/read/29316405/magnesium-zinc-calcium-vitamin-d-co-supplementation-improves-glycemic-control-and-markers-of-cardio-metabolic-risk-in-gestational-diabetes-a-randomized-double-blind-placebo-controlled-trial
#3
Maryam Karamali, Shahla Bahramimoghadam, Fateme Sharifzadeh, Zatollah Asemi
To the best our knowledge, data on the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk in gestational diabetes mellitus (GDM) are scarce. The purpose of this study was to establish the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk of GDM patients. Sixty patients with GDM, aged 18-40 years old were randomised into two groups to intake either magnesium-zinc-calcium-vitamin D co-supplements or placebo (n=30 each group) for 6 weeks in a randomized, double-blind, placebo-controlled trial...
January 9, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29258537/gender-differences-and-typical-nutrition-concerns-of-the-diets-of-preschool-children-the-results-of-the-first-stage-of-an-intervention-study
#4
Sylwia Merkiel-Pawłowska, Wojciech Chalcarz
BACKGROUND: Nutrition in children has an important influence on health both in childhood and adulthood. Actions aimed at improving children's nutrition are essential, not only to the children and their families, but also to the whole society. The aim of the study was to present the results of nutrient intake before starting a nutrition and physical activity intervention programme, to investigate gender differences in nutrient intake and to discuss whether the preschoolers' nutrient intake is similar to the intake of their peers from other countries...
December 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29248801/plasma-magnesium-is-inversely-associated-with-epstein-barr-virus-load-in-peripheral-blood-and-burkitt-lymphoma-in-uganda
#5
Ravell Juan, Isaac Otim, Hadijah Nabalende, Ismail D Legason, Steven J Reynolds, Martin D Ogwang, Christopher M Ndugwa, Vickie Marshall, Denise Whitby, James J Goedert, Eric A Engels, Kishor Bhatia, Michael J Lenardo, Sam M Mbulaiteye
BACKGROUND: Epstein-Barr virus (EBV) causes endemic Burkitt lymphoma (eBL). EBV control was improved by magnesium (Mg2+) supplementation in XMEN, an X-linked genetic disease associated with Mg2+ deficiency, high circulating EBV levels (viral loads), and EBV-related lymphomas. We, therefore, investigated the relationship between Mg2+ levels and EBV levels and eBL in Uganda. METHODS: Plasma Mg2+ was measured in 45 women with low or high circulating EBV levels, 40 pediatric eBL cases, and 79 healthy children...
December 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29248228/effects-of-magnesium-source-and-monensin-on-nutrient-digestibility-and-mineral-balance-in-lactating-dairy-cows
#6
A W Tebbe, D J Wyatt, W P Weiss
The interaction of monensin and 2 supplemental Mg sources (MgO and MgSO4) on total-tract digestion of minerals and organic nutrients and milk production was evaluated in lactating dairy cattle. Eighteen multiparous Holstein cows (139 ± 35 DIM) were used in a split-plot experiment with 0 or 14 mg/kg diet DM of monensin as the whole-plot treatments and Mg source as split-plot treatments. During the entire experiment (42 d), cows remained on the same monensin treatment but received a different Mg source in each period (21 d) of the Latin square...
December 13, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29243316/effect-of-lactic-acid-bacteria-treated-king-grass-silage-on-the-performance-traits-and-serum-metabolites-in-new-zealand-white-rabbits-oryctolagus-cuniculus
#7
A A Shah, X Yuan, R U Khan, T Shao
This study examined the effects of Lactobacillus plantarum and Pediococcus acidilactici-treated silage of King grass (Pennisetum purpureophoides) on the productive traits and blood biochemistry of New Zealand white (NZW) rabbits. King grass was ensiled without or with L. plantarum (T1), P. acidilactici (T2) and P. acidilactici + L. plantarum (T3). A total of 72 male NZW rabbits (6 weeks) of similar weight and appearance were housed in groups in metallic cages in a completely randomized design. The performance traits, daily feed intake, body weight gain and feed convention ratio were not affected by the silage treatment...
December 15, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29229321/the-role-of-aspirin-heparin-and-other-interventions-in-the-prevention-and-treatment-of-fetal-growth-restriction
#8
REVIEW
Katie M Groom, Anna L David
Fetal growth restriction and related placental pathologies such as preeclampsia, stillbirth, and placental abruption are believed to arise in early pregnancy when inadequate remodeling of the maternal spiral arteries leads to persistent high-resistance and low-flow uteroplacental circulation. The consequent placental ischaemia, reperfusion injury, and oxidative stress are associated with an imbalance in angiogenic/antiangiogenic factors. Many interventions have centered on the prevention and/or treatment of preeclampsia with results pertaining to fetal growth restriction and small-for-gestational-age pregnancy often included as secondary outcomes because of the common pathophysiology...
December 8, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29225900/decreased-magnesium-status-may-mediate-the-increased-cardiovascular-risk-associated-with-calcium-supplementation
#9
EDITORIAL
James J DiNicolantonio, Mark F McCarty, James H O'Keefe
No abstract text is available yet for this article.
2017: Open Heart
https://www.readbyqxmd.com/read/29223451/mineralization-in-newborn-calves-contributes-to-health-improve-the-antioxidant-system-and-reduces-bacterial-infections
#10
Patrícia Glombowsky, Aleksandro S da Silva, Natan M Soldá, Gabriela M Galli, Angelisa H Biazus, Gabriela Campigotto, Nathieli B Bottari, Rejane S Sousa, Maiara C Brisola, Lenita M Stefani, Matheus D Baldissera, Marta L R Leal, Vera M Morsch, Maria Rosa C Schetinger, Gustavo Machado
The first phase of life of dairy calves has elevated mortality indices linked with low immunity and sanitary challenges, mainly bacterial infections are involved in the pathogenesis of diarrhea, the leading cause of death. Also, other important problem is the nutritional deficiencies, such as the mineral deficiency. Thus, the aim of this study was to evaluate whether an intramuscular mineral supplementation based on selenium, copper, potassium, magnesium and phosphorus possess beneficial effects on health of dairy calves...
December 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29211007/contribution-of-dietary-supplements-to-nutritional-adequacy-in-various-adult-age-groups
#11
Jeffrey B Blumberg, Balz Frei, Victor L Fulgoni, Connie M Weaver, Steven H Zeisel
Many Americans have inadequate intakes of several nutrients. The Dietary Guidelines for Americans 2015-2020 specifically identified vitamins A, C, D and E, calcium, magnesium, iron, potassium, choline and fiber as "underconsumed nutrients". Based on nationally representative data in 10,698 adults from National Health and Nutrition Examination Surveys (NHANES), 2009-2012, assessments were made of age-group differences in the impact of dietary supplements on nutrient intake and inadequacies. Compared to food alone, use of any dietary supplement plus food was associated with significantly (p < 0...
December 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29206907/a-novel-bioactive-derivative-of-eicosapentaenoic-acid-epa-suppresses-intestinal-tumor-development-in-apc%C3%AE-14-mice
#12
Masako Nakanishi, Matthew P Hanley, Ruochen Zha, Yuichi Igarashi, Mark A Hull, Gary Mathias, Frank Sciavolino, James J Grady, Daniel W Rosenberg
Familial adenomatous polyposis (FAP) is a genetic disorder characterized by the development of hundreds of polyps throughout the colon. Without prophylactic colectomy, most individuals with FAP develop colorectal cancer at an early age. Treatment with eicosapentaenoic acid (EPA) in the free fatty acid form (EPA-FFA) has been shown to reduce polyp burden in FAP patients. Since high-purity EPA-FFA is subject to rapid oxidation, a stable form of EPA compound has been developed in the form of magnesium l-lysinate bis-eicosapentaenoate (TP-252)...
December 1, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29198048/magnesium-in-breast-cancer-what-is-its-influence-on-the-progression-of-this-disease
#13
REVIEW
Priscyla Maria Vieira Mendes, Daila Leite Chaves Bezerra, Loanne Rocha Dos Santos, Raísa de Oliveira Santos, Stéfany Rodrigues de Sousa Melo, Jennifer Beatriz Silva Morais, Juliana Soares Severo, Sabas Carlos Vieira, Dilina do Nascimento Marreiro
Breast cancer is a disease of high mortality, characterized by the progressive accumulation of mutations that contribute to the uncontrolled development of breast tissue cells. Literature shows that disturbances in mineral homeostasis, such as magnesium, may interfere with tumor progression. The objective of this study is to provide updated information about magnesium's role in the pathogenesis of breast cancer. A review of literature was carried out from a search for articles in the PubMed and CAPES Periodicals databases published between 1995 and 2016 with the cross-references of the descriptors "magnesium," "breast neoplasms," and "oxidative stress" and the corresponding words in Portuguese...
December 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29196879/the-feasibility-of-physiologically-based-pharmacokinetic-modeling-in-forensic-medicine-illustrated-by-the-example-of-morphine
#14
Nadine Schaefer, Daniel Moj, Thorsten Lehr, Peter H Schmidt, Frank Ramsthaler
In forensic medicine, expert opinion is often required concerning dose and time of intake of a substance, especially in the context of fatal intoxications. In the present case, a 98-year-old man died 4 days after admission to a hospital due to a femur neck fracture following a domestic fall in his retirement home. As he had obtained high morphine doses in the context of palliative therapy and a confusion of his supplemental magnesium tablets with a diuretic by the care retirement home was suspected by the relatives, a comprehensive postmortem examination was performed...
December 1, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29190155/purified-dry-paullinia-cupana-pc-18-extract-for-chemotherapy-induced-fatigue-results-of-two-double-blind-randomized-clinical-trials
#15
Claudia Vaz de Melo Sette, Bárbara Bonaparte Ribas de Alcântara, Jean Henri Maselli Schoueri, Felipe Melo Cruz, Daniel de Iracema Gomes Cubero, Luiz Francisco Pianowski, Luke Joseph Peppone, Fernando Fonseca, Auro Del Giglio
Fatigue is frequent among oncologic patients. Unpurified Paullinia cupana dry extract showed encouraging results for chemotherapy-induced fatigue in our previous studies. We report two randomized, double-blind studies with a standardized dry purified Paullinia cupana extract named PC-18. For both studies, we recruited early breast cancer patients who had an increase in their fatigue scores after their first cycle of adjuvant chemotherapy. In the first study, we compared an oral dose of 37.5 mg of PC-18 twice daily with placebo...
November 30, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29183350/sequential-activation-of-the-akt-pathway-in-human-osteoblasts-treated-with-oscarvit-a-bioactive-product-with-positive-effect-both-on-skeletal-pain-and-mineralization-in-osteoblasts
#16
Tibor Görögh, Elgar S Quabius, Alexander Georgitsis, Markus Hoffmann, Sebastian Lippross
BACKGROUND: Oscarvit (OSC) is an in-house preparation consisting of calcium, magnesium, phosphorus, strontium, Vitamin D, and eggshell membrane hydrolysate containing naturally occurring glycosaminoglycans and sulfated glycoproteins. OSC has been used both in an open-label human study and in vitro in osteoblasts. METHODS: Fifteen patients divided into three groups received oral OSC 0.6 g three times daily for 20 days. The main outcome measures were regional skeletal pain over the treatment period...
November 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29182799/inhaled-magnesium-sulfate-in-the-treatment-of-acute-asthma
#17
REVIEW
Rachel Knightly, Stephen J Milan, Rodney Hughes, Jennifer A Knopp-Sihota, Brian H Rowe, Rebecca Normansell, Colin Powell
BACKGROUND: Asthma exacerbations can be frequent and range in severity from mild to life-threatening. The use of magnesium sulfate (MgSO₄) is one of numerous treatment options available during acute exacerbations. While the efficacy of intravenous MgSO₄ has been demonstrated, the role of inhaled MgSO₄ is less clear. OBJECTIVES: To determine the efficacy and safety of inhaled MgSO₄ administered in acute asthma. SPECIFIC AIMS: to quantify the effects of inhaled MgSO₄ I) in addition to combination treatment with inhaled β₂-agonist and ipratropium bromide; ii) in addition to inhaled β₂-agonist; and iii) in comparison to inhaled β₂-agonist...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29171639/nutritional-supplements-in-depressive-disorders
#18
Mónica Martínez-Cengotitabengoa, Ana González-Pinto
There is increasing evidence about the role of nutrients in mental health. An adequate intake of nutrients contributes to better overall health and mental health in particular. Major depression is a severe mental illness with a high prevalence for which effective treatments exist but not in all cases the patient’s remission is achieved. Therefore, it is increasingly aimed at optimizing the supply of nutrients necessary for adequate brain functioning as adjunctive therapy to antidepressant treatment in depressive disorders...
September 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29169161/digoxin-and-hypermagnesuria
#19
Luca Zanoli, Paolo Lentini, Pasquale Fatuzzo
In a recent issue of Nephron, Abu-Amer et al.[<xref ref-type="bibr" rid="ref1">1</xref>] reported the presence of hypermagnesuria in patients following acute intravenous administration of digoxin and suggested that the Na+/K+-ATPase γ-subunit, which is the pharmacological target of digoxin, can play a role in this process. Hypermagnesuria induced by digoxin may have important clinical consequences, particularly in the presence of inherited and acquired conditions associated with hypermagnesuria and hypomagnesemia...
November 23, 2017: Nephron
https://www.readbyqxmd.com/read/29160809/evaluation-of-dietary-intakes-and-supplement-use-in-paralympic-athletes
#20
Robyn F Madden, Jane Shearer, Jill A Parnell
Dietary intakes and supplement use in Paralympic athletes remains largely unexplored, and specialized recommendations are lacking. The aim of this study was to evaluate nutrient intakes and supplement use in high-performance athletes with physical disabilities using three-day food records and a validated dietary supplement use questionnaire. A secondary aim examined gender differences in nutrient and supplement intakes. Male (n = 18) and female (n = 22) athletes were recruited from nine Paralympic sports through sporting organizations, coaches, and social media...
November 21, 2017: Nutrients
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