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Magnesium supplementation

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https://www.readbyqxmd.com/read/29773176/effects-of-zinc-magnesium-and-chromium-supplementation-on-cardiometabolic-risk-in-adults-with-metabolic-syndrome-a-double-blind-placebo-controlled-randomised-trial
#1
Ha-Na Kim, Se-Hong Kim, Young-Mi Eun, Sang-Wook Song
The prevalence of metabolic syndrome (MetS) has been increasing rapidly worldwide. The activities of zinc, magnesium and chromium have a potential association with MetS; therefore, we investigated the effects of zinc, magnesium and chromium supplements on metabolic risk factors in adults with MetS. In this double-blind, placebo controlled randomised study, 32 adults with MetS were included in the zinc, magnesium, and chromium-administered group (n = 16) or the placebo group (n = 16) and received either 300 mg magnesium, 600 μg chromium and 36 mg zinc per day or placebo over a 24-week period...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29769070/serum-magnesium-levels-and-risk-of-coronary-artery-disease-mendelian-randomisation-study
#2
Susanna C Larsson, Stephen Burgess, Karl Michaëlsson
BACKGROUND: Observational studies have shown that serum magnesium levels are inversely associated with risk of cardiovascular disease, but whether this association is causal is unknown. We conducted a Mendelian randomisation study to investigate whether serum magnesium levels may be causally associated with coronary artery disease (CAD). METHODS: This Mendelian randomisation analysis is based on summary-level data from the CARDIoGRAMplusC4D consortium's 1000 Genomes-based genome-wide association meta-analysis of 48 studies with a total of 60,801 CAD cases and 123,504 non-cases...
May 17, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29765771/reduction-in-nephrotoxicities-using-short-hydration-for-chemotherapy-containing-cisplatin-a-consecutive-analysis-of-467-patients-with-thoracic-malignancies
#3
Midori Tanaka, Hidehito Horinouchi, Yasushi Goto, Shintaro Kanda, Yutaka Fujiwara, Hiroshi Nokihara, Noboru Yamamoto, Yuichiro Ohe
Background: Conventional hydration (CH) in chemotherapy containing cisplatin (CDDP) has been recommended to prevent renal toxicity. Although an increasing number of studies have demonstrated the feasibility of short hydration (SH), few large studies have reported the superiority of SH, compared with CH, in terms of nephrotoxicities. Methods: We conducted a consecutive retrospective analysis of 467 patients who had been treated with chemotherapy including CDDP. Statistical analyses were performed to evaluate the risk factors for nephrotoxicities...
2018: ESMO Open
https://www.readbyqxmd.com/read/29759248/qualitative-and-quantitative-analysis-of-human-nails-to-find-correlation-between-nutrients-and-vitamin-d-deficiency-using-libs-and-icp-aes
#4
M A Almessiere, R Altuwiriqi, M A Gondal, R K AlDakheel, H F Alotaibi
In this work, we analysed human fingernails of people who suffer from vitamin D deficiency using the laser-induced breakdown spectroscopy(LIBS) and inductively coupled plasma atomic emission spectroscopy (ICP-AES)techniques. The measurements have been conducted on 71 nail samples collected randomly from volunteers of different genders and ages ranged between 20 and 50 years. The main aim of this study is to find the correlation between vitamin D deficiency and the intensity of some dominated lines in the LIBS spectra...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29753479/production-of-calcium-and-magnesium-enriched-caseins-and-caseinates-by-an-ecofriendly-technology
#5
Félix-André Masson, Sergey Mikhaylin, Laurent Bazinet
Finding new green ways of producing proteins has never been of such critical public interest, both to meet consumers' needs and to preserve the environment. Milk proteins are among the most attractive protein types due to their high nutritional value and attractive functional properties. In this work, the separation of caseins by conventional chemical acidification was compared with electrodialysis with bipolar membrane coupled to an ultrafiltration module (EDBM-UF), a green process that allows the precipitation of caseins by H+ generated in situ by the bipolar membrane and, simultaneously, the production of a separated NaOH stream from OH- electrogenerated by the bipolar membrane...
May 9, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29747386/zinc-magnesium-selenium-and-depression-a-review-of-the-evidence-potential-mechanisms-and-implications
#6
REVIEW
Jessica Wang, Phoebe Um, Barbra A Dickerman, Jianghong Liu
Micronutrient deficiency and depression are major global health problems. Here, we first review recent empirical evidence of the association between several micronutrients—zinc, magnesium, selenium—and depression. We then present potential mechanisms of action and discuss the clinical implications for each micronutrient. Collectively, empirical evidence most strongly supports a positive association between zinc deficiency and the risk of depression and an inverse association between zinc supplementation and depressive symptoms...
May 9, 2018: Nutrients
https://www.readbyqxmd.com/read/29740897/intracellular-free-magnesium-concentration-in-healthy-horses
#7
J C Winter, G Sponder, R Merle, J R Aschenbach, H Gehlen
Equine metabolic syndrome (EMS) is a worldwide disease in horses that parallels human diabetes mellitus type 2. In both diseases, patients show an altered peripheral insulin sensitivity as a key feature. In humans, multiple studies have demonstrated the beneficial effect of magnesium supplementation on insulin sensitivity. However, serum magnesium levels vary and are therefore not a reliable indicator of the patients' magnesium status. Determining the intracellular free magnesium concentration appears to be a more sensitive diagnostic indicator...
May 9, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29738504/changes-of-blood-pressure-and-hemodynamic-parameters-after-oral-magnesium-supplementation-in-patients-with-essential-hypertension-an-intervention-study
#8
Nikolina Banjanin, Goran Belojevic
The objective of this study was to examine the changes of blood pressure and hemodynamic parameters after oral magnesium supplementation in patients with essential hypertension. The single-arm non-blinded intervention study comprised 48 patients (19 men; 29 women) whose antihypertensive therapy was not changed for at least one month. The participants were asked to consume (daily at home) 300 mg of oral magnesium-oxide supplementation product for one month and to have their blood pressure and hemodynamic parameters (thoracic fluid content, stroke volume, stroke index, cardiac output, cardiac index, acceleration index, left cardiac work index and systemic vascular resistance index, heart rate) measured in the hospital before and after the intervention...
May 8, 2018: Nutrients
https://www.readbyqxmd.com/read/29733462/current-and-potential-therapeutic-strategies-for-the-management-of-vascular-calcification-in-patients-with-chronic-kidney-disease-including-those-on-dialysis
#9
REVIEW
Irene Ruderman, Stephen G Holt, Tim D Hewitson, Edward R Smith, Nigel D Toussaint
Patients with CKD have accelerated vascular stiffening contributing significantly to excess cardiovascular morbidity and mortality. Much of the arterial stiffening is thought to involve vascular calcification (VC), but the pathogenesis of this phenomenon is complex, resulting from a disruption of the balance between promoters and inhibitors of calcification in a uremic milieu, along with derangements in calcium and phosphate metabolic pathways. Management of traditional cardiovascular risk factors to reduce VC may be influential but has not been shown to significantly improve mortality...
May 7, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29731763/magnesium-increases-homoeologous-crossover-frequency-during-meiosis-in-zip4-ph1-gene-mutant-wheat-wild-relative-hybrids
#10
María-Dolores Rey, Azahara C Martín, Mark Smedley, Sadiye Hayta, Wendy Harwood, Peter Shaw, Graham Moore
Wild relatives provide an important source of useful traits in wheat breeding. Wheat and wild relative hybrids have been widely used in breeding programs to introduce such traits into wheat. However, successful introgression is limited by the low frequency of homoeologous crossover (CO) between wheat and wild relative chromosomes. Hybrids between wheat carrying a 70 Mb deletion on chromosome 5B ( ph1b ) and wild relatives, have been exploited to increase the level of homoeologous CO, allowing chromosome exchange between their chromosomes...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29728338/carotenoid-production-in-sugarcane-juice-and-synthetic-media-supplemented-with-nutrients-by-rhodotorula-rubra-l02
#11
Mariana de Paula Bonadio, Lidyane Aline de Freita, Márcia Justino Rossini Mutton
In order for the use of biological carotenoids to become feasible, it is necessary to have adequate low cost sources and improved methods of cultivation. The aim of this study was to evaluate the effect of supplementation with nitrogen, phosphorus, zinc, and magnesium, on the biomass and carotenoid volumetric production by yeast Rhodotorula rubra L02 using a complex medium (sugarcane juice) and synthetic media (sucrose and maltose) as substrates. The experimental design used for each substrate was randomized in blocks with 16 treatments and 3 repetitions...
April 25, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29722851/calcium-magnesium-and-whole-milk-intakes-and-high-aggressive-prostate-cancer-in-the-north-carolina-louisiana-prostate-cancer-project-pcap
#12
Susan E Steck, Omonefe O Omofuma, L Joseph Su, Amanda A Maise, Anna Woloszynska-Read, Candace S Johnson, Hongmei Zhang, Jeannette T Bensen, Elizabeth T H Fontham, James L Mohler, Lenore Arab
Background: Calcium and dairy product intakes have been positively associated with prostate cancer risk. An imbalance in concentrations of calcium and magnesium has been associated with multiple chronic diseases, although few studies have examined the relation with prostate cancer aggressiveness. Objective: The goal of this study was to examine the association between dietary intakes of calcium and magnesium, the calcium-to-magnesium ratio (Ca:Mg), and dairy products and prostate cancer aggressiveness...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29710825/impact-of-a-specific-amino-acid-composition-with-micronutrients-on-well-being-in-subjects-with-chronic-psychological-stress-and-exhaustion-conditions-a-pilot-study
#13
Deborah Armborst, Christine Metzner, Birgit Alteheld, Norman Bitterlich, Daniela Rösler, Roswitha Siener
Chronic work-life stress leads to dysfunction of the hypothalamus⁻pituitary⁻adrenal axis, the autonomic nervous system, and the serotonergic system, with resultant impairment of overall well-being. Aim of the study was to improve perceived stress by a specific amino acid composition with micronutrients in the verum versus placebo group. A total of 59 participants (18⁻65 years) with self-reported perceived chronic stress and exhaustion conditions participated in this randomized, double-blind, placebo-controlled study...
April 29, 2018: Nutrients
https://www.readbyqxmd.com/read/29709832/effect-of-magnesium-supplementation-on-endothelial-function-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
Manije Darooghegi Mofrad, Kurosh Djafarian, Hadis Mozaffari, Sakineh Shab-Bidar
BACKGROUND AND AIMS: Findings of past studies are inconsistent regarding the effects of magnesium (Mg) supplementation on endothelial function (EF). We performed this meta-analysis to examine the effects of magnesium supplementation on flow-mediated dilation (FMD) and carotid intima media thickness (CIMT) as markers of EF. METHODS: Literature searches of English publications in MEDLINE and EMBASE databases were conducted up to November 2017. Results are reported as weighted mean difference (MD) with 95% confidence intervals (CI) using random effects model (DerSimonian-Laird method)...
April 14, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29701137/impact-of-food-pantry-donations-on-diet-of-a-low-income-population
#15
Tamara Y Mousa, Jean H Freeland-Graves
OBJECTIVE: This cross-sectional study assessed the effect of food donations on total nutrient intake of clients of a food pantry in Central Texas. METHODS: Nutrient intakes of total, base and food donation diets were estimated for 112 food pantry recipients using specific questionnaires; and then compared to the dietary reference intakes (DRI) and 2015-2020 US Dietary Guidelines. RESULTS: Food donations accounted for more than half of the client's daily intake of energy, carbohydrates, vitamin B6 , phosphorus, copper and selenium...
April 27, 2018: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/29683958/kidney-protective-effect-of-magnesium-supplementation-in-cisplatin-containing-chemotherapy-for-pediatric-cancer-a-retrospective-study
#16
Motohiro Matsui, Yuya Saito, Shoko Yamaoka, Yuichi Yokokawa, Yoshihiko Morikawa, Atsushi Makimoto, Yuki Yuza
In total, 158 chemotherapy courses containing cisplatin for 37 pediatric cases of newly diagnosed cancer were divided into 2 groups depending on whether magnesium (Mg) supplementation was administered (Mg+: 92 courses) or not (Mg-: 66 courses). Renal impairment was defined as grade 2 or higher creatinine elevation (CE) after each chemotherapy course. The incidence of CE in the Mg+ was significantly lower than in the Mg- (9.8% vs. 22.7%; P=0.025). Multivariate analysis revealed that Mg supplementation significantly reduced the incidence of CE (odds ratio, 0...
April 20, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29679349/timeline-bioavailability-of-magnesium-compounds-in-hours-which-magnesium-compound-works-best
#17
Nazan Uysal, Servet Kizildag, Zeynep Yuce, Guven Guvendi, Sevim Kandis, Basar Koc, Aslı Karakilic, Ulas M Camsari, Mehmet Ates
Magnesium is an element of great importance functioning because of its association with many cellular physiological functions. The magnesium content of foods is gradually decreasing due to food processing, and magnesium supplementation for healthy living has become increasingly popular. However, data is very limited on the bioavailability of various magnesium preparations. The aim of this study is to investigate the bioavailability of five different magnesium compounds (magnesium sulfate, magnesium oxide, magnesium acetyl taurate, magnesium citrate, and magnesium malate) in different tissues...
April 21, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29672725/down-regulated-expression-of-magnesium-transporter-genes-following-a-high-magnesium-diet-attenuates-sciatic-nerve-crush-injury
#18
Ying-Ju Chen, Fu-Chou Cheng, Chun-Jung Chen, Hong-Lin Su, Meei-Ling Sheu, Jason Sheehan, Hung-Chuan Pan
BACKGROUND: Magnesium supplementation has potential for use in nerve regeneration. The expression of some magnesium transporter genes is reflective of the intracellular magnesium levels. OBJECTIVE: To assess the expression of various magnesium transporter genes as they relate to neurological alterations in a sciatic nerve injury model. METHODS: Sciatic nerve injury was induced in rats, which were then fed either basal or high magnesium diets...
April 17, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29663176/serum-magnesium-and-risk-of-incident-heart-failure-in-older-men-the-british-regional-heart-study
#19
Sasiwarang Goya Wannamethee, Olia Papacosta, Lucy Lennon, Peter H Whincup
To examine the association between serum magnesium and incident heart failure (HF) in older men and investigate potential pathways including cardiac function, inflammation and lung function. Prospective study of 3523 men aged 60-79 years with no prevalent HF or myocardial infarction followed up for a mean period of 15 years, during which 268 incident HF cases were ascertained. Serum magnesium was inversely associated with many CVD risk factors including prevalent atrial fibrillation, lung function (FEV1 ) and markers of inflammation (IL-6), endothelial dysfunction (vWF) and cardiac dysfunction [NT-proBNP and cardiac troponin T (cTnT)]...
April 17, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29660401/intravenous-fosfomycin-for-pulmonary-exacerbation-of-cystic-fibrosis-real-life-experience-of-a-large-adult-cf-centre
#20
G Spoletini, M Kennedy, L Flint, T Graham, C Etherington, N Shaw, P Whitaker, M Denton, I Clifton, D Peckham
BACKGROUND: The increased prevalence of multi-drug resistant strains of P.aeruginosa and allergic reactions among adult patients with cystic fibrosis (CF) limits the number of antibiotics available to treat pulmonary exacerbations. Fosfomycin, a unique broad spectrum bactericidal antibiotic, might offer an alternative therapeutic option in such cases. AIM: To describe the clinical efficacy, safety and tolerability of intravenous fosfomycin in combination with a second anti-pseudomonal antibiotic to treat pulmonary exacerbations in adult patients with CF...
April 13, 2018: Pulmonary Pharmacology & Therapeutics
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