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https://www.readbyqxmd.com/read/28330415/novel-detection-of-placental-insufficiency-by-magnetic-resonance-imaging-in-the-nonhuman-primate
#1
Jamie O Lo, Victoria H J Roberts, Matthias C Schabel, Xiaojie Wang, Terry K Morgan, Zheng Liu, Colin Studholme, Christopher D Kroenke, Antonio E Frias
The placenta is a vital organ necessary for healthy fetal development. Placental insufficiency creates an in utero environment where the fetus is at risk of insufficient oxygen or nutrient exchange. This is primarily caused by impairment of either maternal or fetal circulation or vascular thrombosis such as placental infarction. As a result of placental dysfunction, affected fetuses may be growth restricted, neurologically impaired, and at risk of increased morbidity and mortality. In a cohort of 4 pregnant Rhesus macaques, we describe antenatal detection of naturally occurring intrauterine growth restriction (IUGR) and aberrant fetal neurodevelopment in 1 animal...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28328535/the-assessment-of-labor-a-brief-history
#2
Wayne R Cohen, Emanuel A Friedman
In the 1930s, investigators in the US, Germany and Switzerland made the first attempts to quantify the course of labor in a clinically meaningful way. They emphasized the rupture of membranes as a pivotal event governing labor progress. Attention was also placed on the total number of contractions as a guide to normality. Beginning in the 1950s, Friedman determined that changes in cervical dilatation and fetal station over time were the most useful parameters for the assessment of labor progress. He showed all normal labors had similar patterns of dilatation and descent, differing only in the durations and slopes of their component parts...
March 22, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28320495/parent-infant-skin-to-skin-contact-following-birth-history-benefits-and-challenges
#3
Jessie Marie Hubbard, Kindsey Rae Gattman
It is a practice with strong roots in nature and has a significant influence on health outcomes, particularly for at-risk newborns in low-resource settings. In this comprehensive review, benefits of SSC for newborns, mothers, and fathers after vaginal and cesarean births are discussed as well as the benefits of SSC observed for infants in the NICU. Barriers to SSC practice implementation are discussed, and proposed solutions and recommendations are offered. By understanding the many benefits of SSC and strategies for implementation, health care providers can best support and promote this high-quality, evidence-based practice with mothers, newborns, and their families...
March 1, 2017: Neonatal Network: NN
https://www.readbyqxmd.com/read/28282770/using-a-multifaceted-quality-improvement-initiative-to-reverse-the-rising-trend-of-cesarean-births
#4
Dotun Ogunyemi, Sara McGlynn, Anne Ronk, Patricia Knudsen, Tonyie Andrews-Johnson, Angeline Raczkiewicz, Andrew Jovanovski, Sangeeta Kaur, Mark Dykowski, Mark Redman, Ray Bahado-Singh
PURPOSE: National efforts exist to safely reduce the rate of cesarean delivery, a major source of increased morbidity and healthcare costs. This is a report of a quality improvement study targeting reduction of primary cesarean deliveries. MATERIALS AND METHODS: From March 2014 to March 2016, interventions included a nested case-control review of local risk factors, provider and patient education, multidisciplinary reviews based on published guidelines with feedback, provider report cards, commitment to labor duration guidelines, and a focus on natural labor...
February 28, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28279445/a-comprehensive-analysis-of-continuous-epidural-analgesia-s-effect-on-labor-and-neonates-in-maternal-hypertensive-disorder-patients
#5
Bin Han, Mingjun Xu
BACKGROUND: Maternal hypertensive disorder is one of the most common and severe medical complications during pregnancy. Epidural analgesia administration is widely used during labor process. AIM: To evaluate the potential advantage or disadvantage of continuous epidural analgesia's on labor and neonates for maternal hypertensive disorder patients comprehensively. METHODS: We have retrospectively analyzed 232 patients who diagnosed as maternal hypertensive disorder in our hospital since 2015...
January 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/28260290/-the-influence-of-the-intrapartum-inventions-on-the-maternal-and-neonatal-outcomes-of-vaginal-birth-after-cesarean
#6
S W Wu, D He, W Y Zhang
Objective: To investigate the maternal and neonatal outcomes after different intrapartum interventions for vaginal birth after cesarean (Vaginal Birth After Cesarean-section, VBAC). Methods: One hundred and forty three cases in Beijing Obstetrics & Gynecology Hospital, Capital Medical University from January 2015 to November 2016 were selected retrospectively.The relationship between the intrapartum inventions such as induction style, oxytocin usage and spinal analgesia and the maternal and neonatal outcomes such as delivery way, labor time, postpartum hemorrhage and fetal distress were analyzed in pregnant women underwent VBAC...
February 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28246515/efficacy-of-prophylactic-uterine-artery-embolization-before-obstetrical-procedures-with-high-risk-for-massive-bleeding
#7
Heung Kyu Ko, Ji Hoon Shin, Gi Young Ko, Dong Il Gwon, Jin Hyung Kim, Kichang Han, Shin-Wha Lee
OBJECTIVE: To evaluate the safety and efficacy of prophylactic uterine artery embolization (UAE) before obstetrical procedures with high risk for massive bleeding. MATERIALS AND METHODS: A retrospective review of 29 female patients who underwent prophylactic UAE from June 2009 to February 2014 was performed. Indications for prophylactic UAE were as follows: dilatation and curettage (D&C) associated with ectopic pregnancy (cesarean scar pregnancy, n = 9; cervical pregnancy, n = 6), termination of pregnancy with abnormal placentation (placenta previa, n = 8), D&C for retained placenta with vascularity (n = 5), and D&C for suspected gestational trophoblastic disease (n = 1)...
March 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28244302/abdominal-wall-endometriosis-following-cesarean-section-a-study-of-the-growth-rate-of-parietal-endometriosis-implants
#8
Salma Touleimat, Basma Darwish, Maud Vassilieff, Emanuela Stochino Loi, Clotilde Hennetier, Horace Roman
OBJECTIVE: The study aimed to estimate the growth rate of abdominal wall endometriosis (AWE) following Cesarean Section (CS), in order to potentially identify a growth model of endometriosis in vivo. METHODS: This monocentric, retrospective study included 23 patients presenting 26 nodules of post-CS AWE treated by surgical excision. Nodule surface and volume, time-lapse between surgery and AWE as well as the contraception used were noted. A comparison between nodules' features was performed depending on hormonal Vs...
February 27, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28218216/effects-of-previous-laparoscopic-surgical-diagnosis-of-endometriosis-on-pregnancy-outcomes
#9
Hui Li, Hong-Lan Zhu, Xiao-Hong Chang, Yi Li, Yue Wang, Jing Guan, Heng Cui
BACKGROUND: The association between the previous history of endometriosis and obstetric outcomes is still ambiguous. This study aimed to evaluate the effects of previous history of operatively diagnosed endometriosis on pregnancy outcomes. METHODS: A total of 98 primiparous women who had been diagnosed with endometriosis by previous laparoscopic surgery were included in this retrospective cohort study. Pregnancy outcomes were compared between these women (study group) who had a live birth and 300 women without endometriosis (control group) who had a live birth...
February 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28185362/definitive-class-i-human-leukocyte-antigen-expression-in-gestational-placentation-hla-f-hla-e-hla-c-and-hla-g-in-extravillous-trophoblast-invasion-on-placentation-pregnancy-and-parturition
#10
Rinat Hackmon, Lakmini Pinnaduwage, Jianhong Zhang, Stephen J Lye, Daniel E Geraghty, Caroline E Dunk
PROBLEM: The extravillous trophoblasts (EVT) express HLA-C and HLA-G, but HLA-E and HLA-F are the subject of conflicting reports. In this study, we define the HLA expression profile during active EVT placental implantation, pregnancy development, and parturition. METHOD OF STUDY: Immunohistochemistry, q-PCR, and Western blot were used to investigate HLA-C, HLA-E, and HLA-F placental expression across gestation from the early first trimester, late first trimester, second trimester (n=10 in each), preterm gestation (n=6) to elective term cesarean section and term vaginal deliveries (n=12, 38-41 weeks)...
February 10, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28108841/increased-incidence-of-post-term-delivery-and-cesarean-section-after-frozen-thawed-embryo-transfer-during-a-hormone-replacement-cycle
#11
Kazuki Saito, Kenji Miyado, Kenji Yamatoya, Akira Kuwahara, Eisuke Inoue, Mami Miyado, Maki Fukami, Tomonori Ishikawa, Takakazu Saito, Toshiro Kubota, Hidekazu Saito
PURPOSE: This study aimed to clarify the risks of adverse pregnancy outcomes in patients who conceive singletons after frozen embryo transfer (FET) during a hormone replacement cycle and their offspring. METHODS: A retrospective cohort study was conducted in patients who conceived after FET, based on the Japanese-assisted reproductive technology registry for 2013. The perinatal outcomes in cases with live-born singletons achieved through natural ovulatory cycle FET (NC-FET) (n = 6287) or hormone replacement cycle FET (HRC-FET) (n = 10,235) were compared...
January 20, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28046019/indications-for-emergency-intervention-mode-of-delivery-and-the-childbirth-experience
#12
Jonathan E Handelzalts, Avigail Waldman Peyser, Haim Krissi, Sigal Levy, Arnon Wiznitzer, Yoav Peled
BACKGROUND: Although the impact of emergency procedures on the childbirth experience has been studied extensively, a possible association of childbirth experience with indications for emergency interventions has not been reported. OBJECTIVES: To compare the impacts on childbirth experience of 'planned' delivery (elective cesarean section and vaginal delivery) versus 'unplanned' delivery (vacuum extraction or emergency cesarean section); the intervention itself (vacuum extraction versus emergency cesarean section); and indications for intervention (arrest of labor versus risk to the mother or fetus)...
2017: PloS One
https://www.readbyqxmd.com/read/28044379/the-lack-of-natural-processes-of-delivery-and-neonatal-intensive-care-treatment-lead-to-impaired-cytokine-responses-later-in-life
#13
Maria-Viola Martikainen, Leea Keski-Nisula, Hermina Jakupović, Anne M Karvonen, Juha Pekkanen, Maija-Riitta Hirvonen, Marjut Roponen
PROBLEM: Birth-related factors and neonatal treatments could affect the maturation of immune system and thus have lasting effects on immune responses. We investigated the effect of obstetric factors other than being born by cesarean section on immune responses later in life. METHOD OF STUDY: Regulatory, inflammatory, TH1 and TH2 cytokines, and a chemokine were analyzed in unstimulated and Toll-like receptors (TLRs) 2-, 3-, and 4-stimulated PBMCs of teenagers born by cesarean delivery (CD; N=79)...
January 3, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/27940721/weight-change-nomograms-for-the-first-month-after-birth
#14
Ian M Paul, Eric W Schaefer, Jennifer R Miller, Michael W Kuzniewicz, Sherian X Li, Eileen M Walsh, Valerie J Flaherman
OBJECTIVE: Clinicians expect newborns to surpass birth weight by age 10 to 14 days, yet few studies have examined the natural history of weight change in the weeks after birth. We sought to determine the distribution of weight loss and subsequent regain during the first month, the proportion not surpassing birth weight by 14 and 21 days, and whether findings differed by delivery mode. METHODS: For 161 471 singleton neonates delivered at ≥36 weeks' gestation at Kaiser Permanente Northern California Medical Centers between 2009 and 2013 and weighing 2000 to 5000 g at birth, we extracted daily weights from inpatient electronic records and weights from outpatient visits in the first month...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27870738/persistent-pain-after-cesarean-delivery-and-vaginal-delivery-a-prospective-cohort-study
#15
J Petter Kainu, Erja Halmesmäki, Kari T Korttila, P Johanna Sarvela
BACKGROUND: Persistent pain after cesarean delivery and vaginal delivery has been the subject of only a few research articles. The primary outcome of our prospective study was the incidence of persistent pain and its association to mode of delivery. We also studied the nature and intensity of pain after delivery. METHODS: A questionnaire was distributed on postpartum day 2 to 1052 women who had given birth vaginally and to 502 who had undergone cesarean delivery in a tertiary maternity hospital in Helsinki, Finland, in 2010...
December 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27761688/whose-values-whose-risk-exploring-decision-making-about-trial-of-labor-after-cesarean
#16
Sonya Charles, Allison B Wolf
In this article, we discuss decision making during labor and delivery, specifically focusing on decision making around offering women a trial of labor after cesarean section (TOLAC). Many have discussed how humans are notoriously bad at assessing risks and how we often distort the nature of various risks surrounding childbirth. We will build on this discussion by showing that physicians make decisions around TOLAC not only based on distortions of risk, but also based on personal values (i.e. what level of risk are you comfortable with or what types of risks are you willing to take) rather than medical data (or at least medical data alone)...
October 20, 2016: Journal of Medical Humanities
https://www.readbyqxmd.com/read/27619845/congenital-and-perinatal-complications-of-chikungunya-fever-a-latin-american-experience
#17
Jaime R Torres, Luiza H Falleiros-Arlant, Lourdes Dueñas, Jorge Pleitez-Navarrete, Doris M Salgado, José Brea-Del Castillo
BACKGROUND: During the years 2014 and 2015, the Region of the Americas underwent a devastating epidemic of chikungunya virus (CHIKV) of the Asian genotype, resulting in millions of affected individuals. However, epidemiological and clinical information on this experience is scarce. Prior knowledge of congenital and neonatal illness caused by CHIKV is limited and almost exclusively based on data obtained from a single outbreak of the East/Central/South African (ECSA) genotype. The effect of chikungunya fever (CHIKF) on pregnancy outcomes and its consequences for infants born to infected mothers at the peak of the epidemic wave in Latin America are reviewed herein...
October 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27512693/the-effect-of-an-instructional-program-based-on-health-belief-model-in-decreasing-cesarean-rate-among-primiparous-pregnant-mothers
#18
Laleh Hassani, Teamur Aghamolaei, Amin Ghanbarnejad, Sakineh Dadipoor
INTRODUCTION: Although cesarean section has saved many mothers' and infants' lives, the problem is in its increasing prevalence. According to recent statistics, the current rate of cesarean in Iran is in fact 3-4 times as more than the standard rate defined by WHO. Therefore, the present study is aimed to estimate the effect of an instructional program based on health belief model on reducing cesarean rate among primiparous pregnant women. MATERIALS AND METHODS: In this semi-experimental research, 60 primiparous women who had visited Bandar Abbas Healthcare Centers were selected as the subjects...
2016: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/27445443/a-natural-twin-hospital-birth-my-birth-story
#19
Jamie Linn Mueller
In this column, the author describes the vaginal birth of her twin daughters. Despite impending complications in the last weeks of her pregnancy that might have required a cesarean, this mother was committed to doing everything possible to give birth naturally. With the support of her husband as well as the obstetrician and the nurse, she was able to give birth to her daughters vaginally.
2016: Journal of Perinatal Education
https://www.readbyqxmd.com/read/27408218/effect-of-antenatal-expression-of-breast-milk-at-term-in-reducing-breast-feeding-failures
#20
G Singh, R Chouhan, K Sidhu
BACKGROUND: Though breast feeding is natural, during the first 2-3 days, when enough breast milk is not available with mother, she may introduce bottle feeding erroneously for improving nutrition to her baby. We studied the effect of antenatal expression of breast milk at term in reducing breast feeding failure as compared to conventional method of initiation of breast feeding. METHODS: A prospective study was carried out in 180 booked cases at term. Daily expression of breast milk at least once a day after 37 weeks of pregnancy was introduced in randomly selected 90 pregnant ladies...
April 2009: Medical Journal, Armed Forces India
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