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https://www.readbyqxmd.com/read/29792653/editorial-comment-the-protective-effect-of-papaverine-and-alprostadil-in-rat-testes-after-ischemia-and-reperfusion-injury
#1
EDITORIAL
Fernando Lorenzini
No abstract text is available yet for this article.
May 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29788990/impact-of-anticoagulation-and-vasoactive-medication-on-regained-radial-artery-patency-after-catheterization-a-case-control-study
#2
C Rammos, A Burghardt, J Lortz, O Azizy, R A Jánosi, M Steinmetz, T Rassaf
BACKGROUND: Radial artery access is the primary approach for coronary interventions due to higher safety profile in comparison to femoral access. Radial artery occlusion (RAO) is the main complication of transradial catheterization that can lead to severe symptoms and a permanent artery occlusion. The incidence of RAO after transradial access ranges from 5 to 38% and data regarding treatment is scarce. Whether anticoagulation and vasoactive medication provides an additional benefit in recovery of radial artery patency (RAP) after catheterization has not been investigated in detail...
May 22, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29769055/one-visceral-artery-may-be-enough-successful-pancreatectomy-in-a-patient-with-total-occlusion-of-the-celiac-and-superior-mesenteric-arteries
#3
Evangelos Tagkalos, Florian Jungmann, Hauke Lang, Stefan Heinrich
BACKGROUND: The anatomic variations of the visceral arteries are not uncommon. The liver arterial blood supply shows 50% variability between humans, with the most common anatomy being one hepatic artery arising from the celiac trunk and one pancreatico-duodenal arcade between the celiac trunk and the superior mesenteric artery. Occlusion of one artery are mostly asymptomatic but may become clinically relevant when surgery of the liver, bile duct or the pancreas is required. If these pathologies are not reversible, an oncologic pancreatic head resection cannot be performed...
May 16, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29751719/-panax-notoginseng-extract-combined-with-alprostadil-in-treatment-of-arteriosclerosis-obliterans-meta-analysis
#4
(no author information available yet)
To evaluate the clinical efficacy of Panax notoginseng extract combined with alprostadil in the treatment of arteriosclerosis occlusion and investigate its effects on the degree of atherosclerosis. CNKI, Wanfang, VIP journal database, Chinese biomedical literature database(CBM), PubMed, the Cochrane Library and Science Citation Index(SCI) database were searched between inception to December 2017 for relevant studies. Two researchers independently screened and extracted the literature in strict accordance with the inclusion criteria and exclusion criteria...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29728334/intracoronary-infusion-of-alprostadil-and-nitroglycerin-with-targeted-perfusion-microcatheter-in-stemi-patients-with-coronary-slow-flow-phenomenon
#5
Xincheng Sheng, Song Ding, Heng Ge, Yujun Sun, Lingcong Kong, Jie He, Jun Pu, Ben He
BACKGROUND: The treating aims of ST-segment elevation myocardial infarction (STEMI) are vessels recanalization and coronary flow restoration. Coronary slow flow phenomenon (CSFP) is one of the common complications in STEMI patients after percutaneous coronary intervention (PCI) and leads to a higher incidence of adverse clinical outcomes. Alprostadil is a kind of liposomal prostaglandin E1 with beneficial effects on vasodilation, platelet disaggregation and fibrinolysis. But it still remains unclear that whether alprostadil can improve the coronary perfusion in STEMI patients with CSFP after PCI...
April 25, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29703002/embolic-retinal-and-choroidal-vascular-occlusion-after-peribulbar-triamcinolone-injection-a-case-report
#6
Gang Li, Dongdong Xu, Zhirou Hu, Hui Li
RATIONALE: Retinal and choroidal vascular occlusion is a vision-threatening complication of therapeutic injections in the facial region. The early identification and early treatment are necessary to reduce the risk of harm to the patient. PATIENT CONCERNS: We report an extremely rare case of embolic retinal and choroidal vascular occlusion after peribulbar triamcinolone injection in a patient with thyroid-associated ophthalmopathy. DIAGNOSES: Central retinal artery occlusion...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29617080/the-protective-effect-of-papaverine-and-alprostadil-in-rat-testes-after-ischemia-and-reperfusion-injury
#7
Mehmet Ali Karagoz, Omer Gokhan Doluoglu, Hatice Ünverdi, Berkan Resorlu, Mehmet Melih Sunay, Arif Demirbas, Tolga Karakan, Arif Aydin
OBJECTIVE: To investigate the effect of papaverine and alprostadil on testicular torsion-detorsion injury in rats. MATERIALS AND METHODS: A total of 40 male Wistar-Albino rats were used in this study. Four hours of right testicular torsion was applied to each group, excluding sham operated group. The torsion-detorsion (T/D), T/D + papaverine and T/D + alprostadil groups received saline, papaverine and alprostadil at the same time as surgical detorsion, respectively...
February 28, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29578415/-endothelial-dysfunction-and-microscirculation-features-in-patients-with-high-risk-of-development-of-reperfusion-syndrome-in-conditions-of-reconstruction-arterial-operations
#8
А Kolotylo, I Venher, S Kostiv, A Iftodiy
Aim - to study the state of the microcirculatory bed and the endothelial system in patients at risk of developing reperfusion syndrome and suggest methods for their correction. The work included 29 patients with obliterating diseases of the abdominal aorta and lower limb arteries with a high risk of developing reperfusion complications. Two groups of patients were identified. Group I - 8 patients, preoperative preparation include the generally accepted approaches. Group II - 21 patients whose preoperative preparation included, in addition to preparations for improving rheological blood conditions, prolonged epidural anesthesia, intravenous injection of hydroxyethylstarches, korvetin and alprostadil...
February 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29516548/malignant-atrophic-papulosis-with-motor-aphasia-and-intestinal-perforation-a-case-report-and-review-of-published-works
#9
Pan Hu, Zhi Mao, Chao Liu, Xin Hu, Hongjun Kang, Feihu Zhou
Malignant atrophic papulosis (MAP) is a rare type of obliterating vasculopathy that can present as pure cutaneous lesions or a systemic entity affecting multiple organs. Systemic disease, such as gastrointestinal or central nervous system involvement, may predispose the patients to poorer or even fatal outcomes. We present a 30-year-old female patient with systemic manifestation of MAP 10 days after delivery of a full-term pregnancy who subsequently developed motor aphasia and intestinal perforation. The patient was administrated empirical treatment with an antiplatelet, anticoagulant, methylprednisolone sodium succinate and alprostadil...
March 8, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29464656/non-invasive-management-options-for-erectile-dysfunction-when-a-phosphodiesterase-type-5-inhibitor-fails
#10
REVIEW
Mary Lee, Roohollah Sharifi
Phosphodiesterase type 5 inhibitors (PDE5Is) are the drug of choice for medical management of erectile dysfunction (ED). On-demand PDE5Is have an overall efficacy of 60-70% for ED; 30-35% of patients fail to respond to a PDE5I, and 30-50% of non-responders can be salvaged with detailed counseling on proper use and physician follow-up to ensure that the patient has been prescribed an appropriate and full PDE5I clinical trial. True non-responders may be offered intracavernosal injections of erectogenic drugs, intraurethral alprostadil, or surgical insertion of a penile prosthesis...
March 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29429213/-effect-of-acidic-oligosaccharides-on-p-selectin-of-pulmonary-hypertensive-rats-induced-by-monocrotaline
#11
Z Feng, Y Hu, N N An, W J Feng, T Hu, Y J Mao
Objective: To observe the effects of acidic oligosaccharides (AOS) on P-selectin levels in the serum and the pulmonary arteries of pulmonary hypertensive rats induced by monocrotaline. Methods: Sixty healthy adult male Sprague-Dawley rats were randomly divided into control group ( n =10), model group ( n =10), Alprostadil group ( n =10), low-dose AOS group (AOS-L, n =10), medium-dose AOS group (AOS-M, n =10) and high-dose AOS group (AOS-H, n =10). The rat model of pulmonary arterial hypertension was made by a single intraperitoneal injection of monocrotaline(60 mg/kg)...
February 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29311680/inhibition-of-insulin-resistance-by-pge1-via-autophagy-dependent-fgf21-pathway-in-diabetic-nephropathy
#12
Wei Wei, Xing-Rong An, Shi-Jie Jin, Xiao-Xue Li, Ming Xu
Insulin resistance is a critical process in the initiation and progression of diabetic nephropathy (DN). Alprostadil (Prostaglandin E1, PGE1) had protective effects on renal function. However, it is unknown whether PGE1 inhibited insulin resistance in renal tubule epithelial cells via autophagy, which plays a protective role in DN against insulin resistance. Insulin resistance was induced by palmitic acid (PA) in human HK-2 cells, shown as the decrease of insulin-stimulated AKT phosphorylation, glucose transporter-4 (GLUT4), glucose uptake and enhanced phosphorylation of insulin receptor substrate 1(IRS-1) at site serine 307 (pIRS-1ser307) and downregulated expression of IRS-1...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29277884/penile-glans-necrosis-developing-after-internal-pudendal-arterial-embolization-a-case-report
#13
Tae Nam Kim, Chan Ho Lee, Seung Ryong Baek, Kyung Min Lee, Sangmin Choe, Nam Cheol Park, Hyun Jun Park
Penile glans ischemia or necrosis developing after internal pudendal arterial embolization is very rare; no relevantreport has yet appeared. A 53-year-old male who visited our emergency room because of massive urethral bleedingwas diagnosed with an internal pudendal artery-urethral fistula; he underwent selective embolization of the internalpudendal artery. However, unexpected penile glans ischemic necrosis developed after embolization. We successfullytreated the patients with intravenous infusion of alprostadil, oral pentoxifylline and tadalafil...
March 18, 2018: Urology Journal
https://www.readbyqxmd.com/read/29201206/combined-treatment-of-diabetic-nephropathy-with-alprostadil-and-calcium-dobesilate
#14
Lili Qin, Wenjun Qin, Jianfei Wang, Lin Lin
This study investigated the effects of alprostadil combined with calcium dobesilate on the treatment of diabetic nephropathy. We recruited 80 patients with diabetic nephropathy, who were randomly divided into experimental (n=40) and control (n=40) groups. Patients received high-quality low-protein diabetic diet intervention and subcutaneous injection of insulin to adjust blood glucose, combined with antihypertensive, antiplatelet drugs, and other comprehensive treatments. The control group received alprostadil and the experimental group received alprostadil combined with calcium dobesilate...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29162633/use-of-prostaglandins-in-duct-dependent-congenital-heart-conditions
#15
Yogen Singh, Paraskevi Mikrou
Congenital heart disease (CHD) remains a leading cause of infant mortality, which is even higher in infants with undiagnosed duct-dependent CHDs. Up to 39%-50% of infants with critical CHD are being discharged undiagnosed from the hospital. Infants with duct-dependent critical CHD remain well during the fetal period and may deteriorate when the ductus arteriosus (commonly called 'duct') closes after birth. It is critical to open or maintain ductus arteriosus patent in infants with duct-dependent CHDs. Prostaglandin E1 (alprostadil marketed as 'Prostin VR ') and prostaglandin E2 (dinoprostone) are used to maintain a patent ductus arteriosus and the dose of medication depends on the clinical presentation...
November 21, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29155195/unreliability-of-the-duplex-scan-in-diagnosing-corporeal-venous-occlusive-disease-in-young-healthy-men-with-erectile-deficiency
#16
Giorgio Cavallini, Carlo Maretti
OBJECTIVE: To define the role of cavernosal venous occlusive dysfunction (CVOD) as the only cause of erectile dysfunction (ED). MATERIALS AND METHODS: Patients meeting the CVOD criteria without any risk factors for organic ED were randomized into 2 groups; the end-diastolic velocity (EDV), peak systolic velocity (PSV), and resistive index (RI) of their cavernosal arteries were assessed using color duplex Doppler ultrasound (CDDU) after intracavernous injection (ICI) of 10 µg alprostadil...
March 2018: Urology
https://www.readbyqxmd.com/read/29073785/preventive-effects-of-alprostadil-against-contrast-induced-nephropathy-inpatients-with-renal-insufficiency-undergoing-percutaneous-coronary-intervention
#17
Shi-Cheng Yang, Nai-Kuan Fu, Jing Zhang, Min Liang, Hong-Liang Cong, Wen-Hua Lin, Feng-Shi Tian, Cheng-Zhi Lu, Ting-Ting Sun, Wen-Ya Zhang, Zhen-Hua Ma
We investigated the preventive effect of alprostadil on contrast-induced nephropathy (CIN) in patients with renal insufficiency undergoing percutaneous coronary intervention (PCI). A total of 300 patients with creatinine clearance (crCl) ≤60 mL/min undergoing PCI were randomly assigned to alprostadil or a control group. The primary end point was the incidence of CIN defined as an increase in serum creatinine (Scr) levels by ≥0.5 mg/dL or≥ 25% after administration of the contrast media within 72 hours...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/29043297/clinical-efficacy-of-alprostadil-combined-with-%C3%AE-lipoic-acid-in-the-treatment-of-elderly-patients-with-diabetic-nephropathy
#18
Yan Hong, Jianyun Peng, Xiaoping Cai, Xiaoru Zhang, Yifei Liao, Lejian Lan
OBJECTIVE: To evaluate the effect and toxicity of alprostadil combined with thioctic acid injection in the treatment of patients with diabetic nephropathy (DN). METHODS: Sixty two patients with DN were included in this study and randomly divided into control group (n=32) and experiment group (n=30). Patients in the control group were given alprostadil 20ug+NS 100ml ivgtt, qd and patients in the experiment group were given alprostadil 20ug+NS 100ml ivgtt combined with thioctic acid injection of 0...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29024304/efficacy-of-alprostadil-in-preventing-contrast-induced-nephropathy-in-patients-undergoing-percutaneous-coronary-intervention-a-multicenter-prospective-randomized-controlled-trial
#19
Min Liang, Shicheng Yang, Naikuan Fu, Chengzhi Lu, Fengshi Tian, Xiaochun Xing, Wenhua Lin, Jingjing Liu
BACKGROUND: The role of alprostadil on the prevention of contrast-induced nephropathy (CIN) still remains controversial. The purpose of this study was to examine the effects of short-term alprostadil on the incidence of CIN in patients undergoing elective percutaneous coronary intervention (PCI). METHODS: A total of 480 patients with coronary heart disease undergoing PCI were enrolled in our study and randomly assigned to two groups. The control group (n = 240) was given only hydration therapy and the alprostadil group (n = 240) received intravenous administration of 20 ug/day (diluted with 100 ml normal saline) from 0...
March 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28967058/topical-alprostadil-vitaros%C3%A2-in-the-treatment-of-erectile-dysfunction-after-non-nerve-sparing-robot-assisted-radical-prostatectomy
#20
Pier Andrea Della Camera, Simone Morselli, Gianmartin Cito, Giovanni Tasso, Nicola Laruccia, Andrea Cocci, Antonio Ruffo, Mauro Gacci, Sergio Serni, Marco Carini, Alessandro Natali
OBJECTIVE: The aim of the study is the evaluation of the efficacy and safety of the treatment with topical alprostadil (Vitaros©) in post-robot assisted radical prostatectomy (RARP) rehabilitation therapy of patients with erectile dysfunction (ED). METHODS: Seventy-four patients were enrolled and underwent non-nerve-sparing RARP. Inclusion criteria: age <75, preoperatively International Index of Erectile Function (IIEF-5) >16, erection hardness score (EHS) ≥2, weekly sexual intercourse ≥1, affirmative answers to Sexual Encounter Profile Question (SEP-Q) 2 and SEP-Q3, Charlson Comorbidity Index (CCI) ≤5, Eastern Cooperative Oncology Group (ECOG) performance status ≤1, no moderate/severe cardiovascular disease...
September 22, 2017: Urologia
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