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Foot amputation

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https://www.readbyqxmd.com/read/29443819/chronic-osteomyelitis-with-staphylococcus-aureus-deformation-in-submicron-canaliculi-of-osteocytes-a-case-report
#1
Karen L de Mesy Bentley, Ashlee MacDonald, Edward M Schwarz, Irvin Oh
CASE: A patient presenting with an infected diabetic foot ulcer and Staphylococcus aureus chronic osteomyelitis was studied to validate the clinical importance of bacterial colonization of osteocytic-canalicular networks, as we recently reported in a mouse model. We utilized transmission electron microscopy to describe the deformation of S. aureus, from round cocci to rod-shaped bacteria, in the submicron osteocytic-canalicular networks of amputated bone tissue. CONCLUSION: To our knowledge, this is the first evidence of S...
February 14, 2018: JBJS Case Connector
https://www.readbyqxmd.com/read/29439130/limb-and-person-level-risk-factors-for-lower-limb-amputation-in-the-prospective-seattle-diabetic-foot-study
#2
Edward J Boyko, Amber D Seelig, Jessie H Ahroni
OBJECTIVE: Diabetes is the leading cause of nontraumatic lower-limb amputations in the U.S., but no research has prospectively examined associations between limb-specific measurements and amputation risk among patients without foot ulcer. We investigated amputation risk by limb in relation to the same limb- and person-level factors. RESEARCH DESIGN AND METHODS: We conducted a 22-year prospective study among 1,461 male patients with diabetes without foot ulcer (mean age 62...
February 8, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29437636/outcomes-following-limb-salvage-after-combat-hindfoot-injury-are-inferior-to-delayed-amputation-at-five-years
#3
P M Bennett, T Stevenson, I D Sargeant, A Mountain, J G Penn-Barwell
OBJECTIVES: The surgical challenge with severe hindfoot injuries is one of technical feasibility, and whether the limb can be salvaged. There is an additional question of whether these injuries should be managed with limb salvage, or whether patients would achieve a greater quality of life with a transtibial amputation. This study aims to measure functional outcomes in military patients sustaining hindfoot fractures, and identify injury features associated with poor function. METHODS: Follow-up was attempted in all United Kingdom military casualties sustaining hindfoot fractures...
February 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29437061/mid-term-follow-up-of-patients-with-hindfoot-arthrodesis-with-retrograde-compression-intramedullary-nail-in-charcot-neuroarthropathy-of-the-hindfoot
#4
M Chraim, S Krenn, H M Alrabai, H-J Trnka, P Bock
AIMS: Hindfoot arthrodesis with retrograde intramedullary nailing has been described as a surgical strategy to reconstruct deformities of the ankle and hindfoot in patients with Charcot arthropathy. This study presents case series of Charcot arthropathy patients treated with two different retrograde intramedullary straight compression nails in order to reconstruct the hindfoot and assess the results over a mid-term follow-up. PATIENTS AND METHODS: We performed a retrospective analysis of 18 consecutive patients and 19 operated feet with Charcot arthropathy who underwent a hindfoot arthrodesis using a retrograde intramedullary compression nail...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29434753/smoking-increases-the-risk-of-diabetic-foot-amputation-a-meta-analysis
#5
Min Liu, Wei Zhang, Zhaoli Yan, Xiangzhen Yuan
Accumulating evidence suggests that smoking is associated with diabetic foot amputation. However, the currently available results are inconsistent and controversial. Therefore, the present study performed a meta-analysis to systematically review the association between smoking and diabetic foot amputation and to investigate the risk factors of diabetic foot amputation. Public databases, including PubMed and Embase, were searched prior to 29th February 2016. The heterogeneity was assessed using the Cochran's Q statistic and the I 2 statistic, and odds ratio (OR) and 95% confidence interval (CI) were calculated and pooled appropriately...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29430981/the-diabetic-foot-attack-tis-too-late-to-retreat
#6
Prashanth R J Vas, Michael Edmonds, Venu Kavarthapu, Hisham Rashid, Raju Ahluwalia, Christian Pankhurst, Nikolaos Papanas
The "diabetic foot attack" is one of the most devastating presentations of diabetic foot disease, typically presenting as an acutely inflamed foot with rapidly progressive skin and tissue necrosis, at times associated with significant systemic symptoms. Without intervention, it may escalate over hours to limb-threatening proportions and poses a high amputation risk. There are only best practice approaches but no international protocols to guide management. Immediate recognition of a typical infected diabetic foot attack, predominated by severe infection, with prompt surgical intervention to debride all infected tissue alongside broad-spectrum antibiotic therapy is vital to ensure both limb and patient survival...
February 1, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29414988/laboratory-and-community-based-health-outcomes-in-people-with-transtibial-amputation-using-crossover-and-energy-storing-prosthetic-feet-a-randomized-crossover-trial
#7
Sara J Morgan, Cody L McDonald, Elizabeth G Halsne, Sarah M Cheever, Rana Salem, Patricia A Kramer, Brian J Hafner
Contemporary prosthetic feet are generally optimized for either daily or high-level activities. Prosthesis users, therefore, often require multiple prostheses to participate in activities that span a range of mobility. Crossover feet (XF) are designed to increase the range of activities that can be performed with a single prosthesis. However, little evidence exists to guide clinical prescription of XF relative to traditional energy storing feet (ESF). The objective of this study was to assess the effects of XF and ESF on health outcomes in people with transtibial amputation...
2018: PloS One
https://www.readbyqxmd.com/read/29413782/the-role-of-negative-pressure-wound-therapy-in-salvaging-a-six-year-old-child-s-crushed-foot-a-case-report
#8
Dimitrios Begkas, John Michelarakis, Hristos Mirtsios, Panagiotis Deimedes, Dimitrios Bougiouklis
Crushed extremity is an infrequent injury in children and represents a major challenge for the orthopaedic surgeon. Sometimes the decision making process, whether to amputate or save a limb, is very difficult. Several scoring systems have been developed in order to determine the fate of crushed extremities, but they are not always predictive when patients are children. In the past few years, advances in bone and soft tissue reconstruction techniques have improved outcomes, even in the most extreme cases. Negative Pressure Wound Therapy has become an accepted option in the treatment of crushed limbs...
February 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29412312/burden-of-disease-from-lower-limb-amputations-attributable-to-diabetes-mellitus-in-santa-catarina-state-brazil-2008-2013
#9
Kadine Priscila Bender Dos Santos, Soraia Cristina Tonon da Luz, Luis Mochizuki, Eleonora d'Orsi
The objective was to estimate the burden of disease from lower limb amputations attributable to diabetes mellitus in Santa Catarina State, Brazil, from 2008 to 2013. A descriptive epidemiological study was performed by calculating disability-adjusted life years (DALY). Burden of disease was high, more than 8,000 DALY in men and women. Disability accounted for 93% of DALY and mortality for 7.5%. The burden in men was 5,580.6 DALY, almost double that in women (2,894.8), and the share of the years lost due to disability (YLD) component in men pushed this rate to 67...
February 5, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29410772/the-abrupt-temperature-changes-in-the-plantar-skin-thermogram-of-the-diabetic-patient-looking-in-to-prevent-the-insidious-ulcers
#10
REVIEW
Francisco-J Renero-C
Background: One of the complications of the diabetes mellitus is the amputation of the lower limbs. This complication may be developed after an insidious ulcer, that may be raised by the peripheral neuropathy or the ischaemic limb, and that the ulcer get infected. That is, to develop an ulcer, in the diabetic patient, three factors should be taken into the account, the autonomic nervous system, the blood supply and the inmune system. Methods: In this work, the thermogram is used to identify regions on the plantar skin with blood supply deficiencies and the behaviour of the thermoregulation process...
2018: Diabetic Foot & Ankle
https://www.readbyqxmd.com/read/29409267/uncontrolled-diabetes-as-a-potential-risk-factor-in-tibiotalocalcaneal-fusion-using-a-retrograde-intramedullary-nail
#11
Moses Lee, Woo Jin Choi, Seung Hwan Han, Jinyoung Jang, Jin Woo Lee
BACKGROUND: Tibiotalocalcaneal (TTC) fusion using a retrograde intramedullary (IM) nail is an effective salvage option for terminal-stage hindfoot problems. However, as many patients who receive TTC fusion bear unfavorable medical comorbidities, the risk of nonunion, infection and other complications increases. This study was performed to identify the factors influencing outcomes after TTC fusion using a retrograde IM nail. METHODS: Between September 2008 and February 2012, 34 consecutive patients received TTC fusion using a retrograde IM nail for limb salvage...
July 22, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409204/correction-of-ankle-and-hind-foot-deformity-in-charcot-neuroarthropathy-using-a-retrograde-hind-foot-nail-the-kings-experience
#12
N Vasukutty, H Jawalkar, A Anugraha, R Chekuri, R Ahluwalia, V Kavarthapu
BACKGROUND: Corrective fusion for the unstable deformed hind foot and mid foot in Charcot Neuroarthropathy (CN) is quite challenging and is best done in tertiary centres under the supervision of multidisciplinary teams. METHODS: We present a follow up to our initial report with a series of 42 hind foot corrections in 40 patients from a tertiary level teaching hospital in the United Kingdom. The mean patient age was 59 (33-82). 17 patients had type1diabetes mellitus, 23 had type 2...
April 28, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29400252/first-results-concerning-the-safety-walking-and-satisfaction-with-an-innovative-microprocessor-controlled-four-axes-prosthetic-foot
#13
Andreas Hahn, Ivana Sreckovic, Sebastian Reiter, Milana Mileusnic
BACKGROUND: The microprocessor-controlled foot Meridium is a prosthetic component with adjustable stance-phase characteristics. OBJECTIVES: To investigate subjects' and prosthetists' perception of safety, walking, and satisfaction during first routine fittings. STUDY DESIGN: Multicenter, prospective, observational cohort study. METHODS: Data regarding demographics, fitting process, safety, daily life activities, and satisfaction were obtained through questionnaires...
February 1, 2018: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/29393805/development-of-shared-decision-making-resources-to-help-inform-difficult-healthcare-decisions-an-example-focused-on-dysvascular-partial-foot-and-transtibial-amputations
#14
Matthew Quigley, Michael P Dillon, Stefania Fatone
BACKGROUND: Shared decision making is a consultative process designed to encourage patient participation in decision making by providing accurate information about the treatment options and supporting deliberation with the clinicians about treatment options. The process can be supported by resources such as decision aids and discussion guides designed to inform and facilitate often difficult conversations. As this process increases in use, there is opportunity to raise awareness of shared decision making and the international standards used to guide the development of quality resources for use in areas of prosthetic/orthotic care...
February 1, 2018: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/29390881/efficacy-of-cellular-therapy-for-diabetic-foot-ulcer-a-meta-analysis-of-randomized-controlled-clinical-trials
#15
Ye Zhang, Hong Deng, Zhouping Tang
Diabetes mellitus is a widely spread chronic disease with growing incidence worldwide, and diabetic foot ulcer is one of the most serious complications of diabetes. Cellular therapy has shown promise in the management of diabetic foot ulcer in many preclinical experiments and clinical researches. Here, we performed a meta-analysis to evaluate the efficacy and safety of cellular therapy in the management of diabetic foot ulcer. We systematically searched PubMed, MEDLINE, EMBASE, and Cochrane Library databases from inception to May 2017 for randomized controlled trials assessing the efficacy of cellular therapy in diabetic foot ulcer, and a meta-analysis was conducted...
December 2017: Cell Transplantation
https://www.readbyqxmd.com/read/29389217/foot-kinetics-and-kinematics-profile-in-type-2-diabetes-mellitus-with-peripheral-neuropathy-a-hospital-based-study-from-south-india
#16
Animesh Hazari, Arun G Maiya, Shivashankara K N
BACKGROUND: A kinetic change in thefoot like altered plantar pressure is the most common etiological risk factor for causing foot ulcers among people with diabetes mellitus. Kinematic alterations in joint angle and spatiotemporal parameters of the gait have also been frequently observed in participants with diabetes peripheral neuropathy. Diabetes peripheral neuropathy is the most common long-term standing complication of type 2 diabetes mellitus. It leads to various micro and macrovascular related complication of the foot...
February 1, 2018: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29386704/negative-pressure-wound-therapy-in-the-management-of-mine-blast-injuries-of-lower-limbs-lessons-learnt-at-a-tertiary-care-center
#17
Sanjay Maurya, N Srinath, P S Bhandari
Background: Mine blast injuries of foot are devastating injuries that result in composite tissue loss or amputations. Negative pressure wound therapy has helped in the management of such combat-related wounds. The aim of this study was to report experiences gained in managing such injuries at a tertiary care center. Methods: 17 combatants who sustained mine blast injuries were included in this study. Severity of foot injury was assessed as per Foot and Ankle Severity Score...
October 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/29384887/a-rare-large-cutaneous-chondroid-syringoma-involving-a-toe-a-case-report
#18
Hui Lu, Li-Feng Chen, Qiang Chen, Hui Shen, Zhenfeng Liu
RATIONALE: Chondroid syringoma (CS) occurs mostly on the face and neck, and rarely occurs in the toe. Malignant CS is invasive, grows quickly, and has a high recurrence rate. The presence of a bilobed CS in 1 toe has never been reported in the literature. PATIENT CONCERNS: A 72-year-old male patient presented with a mass in a third toe of his right foot. The mass had slowly grown in 2 years. He felt mild pain and the mass occupied most of the tip of the toe. DIAGNOSES: Radiographs showed a large soft-tissue mass in the third toe of his right foot without any bone destruction...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29382584/incidence-of-diabetic-foot-ulcer-in-japanese-patients-with-type-2-diabetes-mellitus-the-fukuoka-diabetes-registry
#19
Masanori Iwase, Hiroki Fujii, Udai Nakamura, Toshiaki Ohkuma, Hitoshi Ide, Tamaki Jodai-Kitamura, Akiko Sumi, Yuji Komorita, Masahito Yoshinari, Takanari Kitazono
AIMS: Although diabetic foot ulcer (DFU) is a serious diabetic complication, there have been no large-scale epidemiological studies of DFU in Japan. We prospectively investigated the incidences of DFU and limb amputation, the risk for developing DFU, and mortality in Japanese patients with type 2 diabetes. METHODS: We followed 4,870 participants (mean age, 65 years) with type 2 diabetes attending an outpatient diabetes clinic for a median of 5.3 years (follow-up rate, 97...
January 27, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29381248/association-between-biofilm-and-multi-extensive-drug-resistance-in-diabetic-foot-infection
#20
Aslı Vatan, Nese Saltoglu, Mucahit Yemisen, Ilker Inanc Balkan, Serkan Surme, Tayfur Demiray, Birgul Mete, Fehmi Tabak
PURPOSE: We aimed to determine significant risk factors for biofilm production and to investigate the association between antimicrobial resistance profile and biofilm formation in the bacterial isolates obtained from patients with diabetic foot infection (DFI). METHODS: Demographic, clinical, laboratory and outcome data of 165 patients, prospectively recorded and followed between January 2008 and December 2015 by a multidisciplinary committee, were analysed. Standard microbiological methods were adopted...
January 30, 2018: International Journal of Clinical Practice
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