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https://www.readbyqxmd.com/read/29289537/early-postpartum-metabolic-syndrome-in-women-with-or-without-gestational-diabetes-results-from-life-after-gestational-diabetes-ahvaz-cohort-study
#1
Sedigheh Nouhjah, Hajieh Shahbazian, Nahid Shahbazian, Shayesteh Jahanfar, Alireza Jahanshahi, Bahman Cheraghian, Zeinab Dehghan Mohammadi, Niloofar Ghodrati, Sousan Houshmandi
AIMS: This study aimed to determine the prevalence rate of metabolic syndrome and its potential risk factors, 6-12 weeks postpartum in women with GDM compared to women with normal glucose tolerance. METHODS: LAGAs is an ongoing population-based prospective cohort study that started in March 2015 in Ahvaz, Iran. During 11 months of study progression, 176 women with GDM pregnancy and 86 healthy women underwent a fasting glucose test, 75-g OGTT and fasting lipid tests at 6-12 weeks postpartum...
December 22, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29192743/can-pancreatic-cancer-be-detected-by-adrenomedullin-in-patients-with-new-onset-diabetes-the-pacanod-cohort-study-protocol
#2
Laura Antolino, Mara La Rocca, Federico Todde, Elena Catarinozzi, Paolo Aurello, Lucilla Bollanti, Giovanni Ramacciato, Francesco D'Angelo
INTRODUCTION: Pancreatic cancer is a leading cause of cancer-related death. Its diagnosis is often delayed and patients are frequently found to have unresectable disease. Patients diagnosed with new-onset diabetes have an 8-fold risk of harboring pancreatic cancer. Adrenomedullin has been claimed to mediate diabetes in pancreatic cancer. New screening tools are needed to develop an early diagnosis protocol. METHODS: Patients aged 45-75 years within 2 years of first fulfilling the ADA criteria for diabetes will be prospectively enrolled in this study...
November 29, 2017: Tumori
https://www.readbyqxmd.com/read/29054261/development-and-validation-of-various-phenotyping-algorithms-for-diabetes-mellitus-using-data-from-electronic-health-records
#3
Santiago Esteban, Manuel Rodríguez Tablado, Francisco E Peper, Yamila S Mahumud, Ricardo I Ricci, Karin S Kopitowski, Sergio A Terrasa
BACKGROUND AND OBJECTIVE: Recent progression towards precision medicine has encouraged the use of electronic health records (EHRs) as a source for large amounts of data, which is required for studying the effect of treatments or risk factors in more specific subpopulations. Phenotyping algorithms allow to automatically classify patients according to their particular electronic phenotype thus facilitating the setup of retrospective cohorts. Our objective is to compare the performance of different classification strategies (only using standardized problems, rule-based algorithms, statistical learning algorithms (six learners) and stacked generalization (five versions)), for the categorization of patients according to their diabetic status (diabetics, not diabetics and inconclusive; Diabetes of any type) using information extracted from EHRs...
December 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28832911/different-strategies-for-diagnosing-gestational-diabetes-to-improve-maternal-and-infant-health
#4
REVIEW
Diane Farrar, Lelia Duley, Therese Dowswell, Debbie A Lawlor
BACKGROUND: Gestational diabetes mellitus (GDM) is carbohydrate intolerance resulting in hyperglycaemia with onset or first recognition during pregnancy. If untreated, perinatal morbidity and mortality may be increased. Accurate diagnosis allows appropriate treatment. Use of different tests and different criteria will influence which women are diagnosed with GDM. This is an update of a review published in 2011 and 2015. OBJECTIVES: To evaluate and compare different testing strategies for diagnosis of gestational diabetes mellitus to improve maternal and infant health while assessing their impact on healthcare service costs...
August 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28556176/lixisenatide-a-once-daily-prandial-glucagon-like-peptide-1-receptor-agonist-for-the-treatment-of-adults-with-type-2-diabetes
#5
REVIEW
Jennifer M Trujillo, Jennifer Goldman
Lixisenatide, a short-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA), has been available in Europe since 2013 and was recently approved in the United States for the treatment of type 2 diabetes (T2D) as an adjunct to diet and exercise. The objective of this systematic review is to describe the pharmacology, pharmacokinetics, safety, and efficacy of lixisenatide in patients with T2D. We conducted a search of the EMBASE database, limited to human studies with abstracts available in English. Published conference abstracts, limited to the American Diabetes Association (ADA) and the European Association for the Study of Diabetes meetings in 2015, as well as abstracts presented at the ADA meeting in 2016, were also screened...
August 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28459036/consensus-statement-on-dose-modifications-of-antidiabetic-agents-in-patients-with-hepatic-impairment
#6
REVIEW
Kalyan Kumar Gangopadhyay, Parminder Singh
Liver disease is an important cause of mortality in type 2 diabetes mellitus (T2DM). It is estimated that diabetes is the most common cause of liver disease in the United States. Virtually, entire spectrum of liver disease is seen in T2DM including abnormal liver enzymes, nonalcoholic fatty liver disease, cirrhosis, hepatocellular carcinoma, and acute liver failure. The treatment of diabetes mellitus (DM) in cirrhotic patients has particular challenges as follows: (1) about half the patients have malnutrition; (2) patients already have advanced liver disease when clinical DM is diagnosed; (3) most of the oral antidiabetic agents (ADAs) are metabolized in the liver; (4) patients often have episodes of hypoglycemia...
March 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28440515/-interpretation-of-the-international-joint-statement-on-metabolic-surgery-in-the-treatment-algorithm-for-type-2-diabetes
#7
Peng Zhang, Chengzhu Zheng
Along with the soaring prevalence of obesity and type 2 diabetes mellitus (T2DM) globally, metabolic and bariatric surgery (MBS) has been rapidly developing into a major surgical subspecialty. However, the indications, benefits and potential risks of MBS are still controversial so far. In September 2015, the 2nd Diabetes Surgery Summit (DSS-II() was successfully convened, and later on an international joint statement on metabolic surgery in the treatment algorithm for T2DM was released based upon the consensus reached in DSS-II(, aiming to serve as a new global clinical guideline...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28404514/postpartum-glucose-testing-related-factors-and-progression-to-abnormal-glucose-tolerance-in-a-rural-population-with-a-known-history-of-gestational-diabetes
#8
Haydeh Ghajari, Sedigheh Nouhjah, Hajieh Shahbazian, Rohollah Valizadeh, Noorollah Tahery
AIMS: Gestational diabetes is a strong risk factor for postpartum progression to glucose intolerance. The aims of the study were to determine rate of postpartum glucose testing , its related factors and rate of progression to glucose intolerance in women who underwent postpartum glucose testing after pregnancy that complicated by gestational diabetes. MATERIALS: this is a retrospective study and women with gestational diabetes who received prenatal care during 2005-2015 in 3 rural health centers of Khuramshahr (southwestern of Iran) were enrolled...
April 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28279547/performance-of-a-random-glucose-case-finding-strategy-to-detect-undiagnosed-diabetes
#9
Michael E Bowen, Lei Xuan, Ildiko Lingvay, Ethan A Halm
INTRODUCTION: Random glucose <200 mg/dL is associated with undiagnosed diabetes but not included in screening guidelines. This study describes a case-finding approach using non-diagnostic random glucose values to identify individuals in need of diabetes testing and compares its performance to current screening guidelines. METHODS: In 2015, cross-sectional data from non-fasting adults without diagnosed diabetes or prediabetes (N=7,161) in the 2007-2012 National Health and Nutrition Examination Surveys were analyzed...
June 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28270715/if-dsme-were-a-pill-would-you-prescribe-it
#10
Margaret A Powers
EDITOR'S NOTE: This address was delivered by Margaret A. Powers, PhD, RD, CDE, President, Health Care & Education, of the American Diabetes Association (ADA), at the ADA's 76th Scientific Sessions in New Orleans, La., on 11 June 2016. Dr. Powers conducts research and has a clinical practice as a registered dietitian and diabetes educator at the International Diabetes Center at Park Nicollet in Minneapolis, Minn. Her research focuses on improving diabetes outcomes, including factors that affect the clinical, psychosocial, and behavioral aspects of diabetes...
February 2017: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/27879353/2016-health-care-education-presidential-address-if-dsme-were-a-pill-would-you-prescribe-it
#11
Margaret A Powers
This address was delivered by Margaret A. Powers, PhD, RD, CDE, President, Health Care & Education, of the American Diabetes Association (ADA), at the ADA's 76th Scientific Sessions in New Orleans, LA, on 11 June 2016. Dr. Powers conducts research and has a clinical practice as a registered dietitian and diabetes educator at the International Diabetes Center at Park Nicollet in Minneapolis. Her research focuses on improving diabetes outcomes including factors that affect the clinical, psychosocial, and behavioral aspects of diabetes...
December 2016: Diabetes Care
https://www.readbyqxmd.com/read/27859570/diabetes-incidence-and-prevalence-in-hong-kong-china-during-2006-2014
#12
J Quan, T K Li, H Pang, C H Choi, S C Siu, S Y Tang, N M S Wat, J Woo, J M Johnston, G M Leung
AIMS: To estimate recent secular changes in the incidence and prevalence of diabetes and pre-diabetes among Hong Kong Chinese adults, and thus show possible future trends for developing mainland China. METHODS: Based on a complete census of the public sector health records of 6.4 million people from 2006 to 2014, diabetes cases were ascertained using different methods including the World Health Organization (WHO) 2011 guidelines (HbA1c , fasting plasma glucose and glucose tolerance test), American Diabetes Association (ADA) 2015 guidelines (plus random plasma glucose), and additionally recorded diagnosis codes and medication dispensation...
November 12, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27832749/type-2-diabetes-compromises-the-value-of-non-invasively-measured-augmentation-index-in-predicting-the-severity-of-coronary-artery-disease-a-hospital-based-observational-study
#13
Sijing Wu, Yujie Zhou, Yueping Li, Yuyang Liu, Dongmei Shi, Xiaoli Liu, Wei Liu, Yi Yu, Shuo Jia
BACKGROUND: Central hemodynamic indices have been demonstrated to correlate with coronary artery disease (CAD). However, in the context of type 2 diabetes mellitus (DM), this correlation has not been fully illustrated. Therefore, this study was employed to investigate the impact of DM on the correlation between aortic augmentation index and the severity of coronary artery disease. METHODS: In this study, we analyzed 197 patients who underwent coronary angiography at Anzhen Hospital from September 2015 to January 2016...
November 10, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27761942/effects-of-advanced-carbohydrate-counting-guided-by-an-automated-bolus-calculator-in-type-1-diabetes-mellitus-stenoabc-a-12-month-randomized-clinical-trial
#14
RANDOMIZED CONTROLLED TRIAL
E Hommel, S Schmidt, D Vistisen, K Neergaard, M Gribhild, T Almdal, K Nørgaard
AIMS: To test whether concomitant use of an automated bolus calculator for people with Type 1 diabetes carrying out advanced carbohydrate counting would induce further improvements in metabolic control. METHODS: We conducted a 12-month, randomized, parallel-group, open-label, single-centre, investigator-initiated clinical study. We enrolled advanced carbohydrate counting-naïve adults with Type 1 diabetes and HbA1c levels 64-100 mmol/mol (8.0-11.3%), who were receiving multiple daily insulin injection therapy...
May 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27315803/diabetes-and-impaired-fasting-glucose-prediction-using-anthropometric-indices-in-adults-from-maracaibo-city-venezuela
#15
Valmore Bermúdez, Juan Salazar, Joselyn Rojas, María Calvo, Milagros Rojas, Mervin Chávez-Castillo, Roberto Añez, Mayela Cabrera
To determine the predictive power of various anthropometric indices for the identification of dysglycemic states in Maracaibo, Venezuela. A cross-sectional study with randomized, multi-staged sampling was realized in 2230 adult subjects of both genders who had their body mass index (BMI), waist circumference (WC) and waist-height ratio (WHR) determined. Diagnoses of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) were made following ADA 2015 criteria. ROC curves were used to evaluate the predictive power of each anthropometric parameter...
December 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27222389/the-multifaceted-roles-of-adipose-tissue-therapeutic-targets-for-diabetes-and-beyond-the-2015-banting-lecture
#16
Philipp E Scherer
The Banting Medal for Scientific Achievement is the highest scientific award of the American Diabetes Association (ADA). Given in memory of Sir Frederick Banting, one of the key investigators in the discovery of insulin, the Banting Medal is awarded annually for scientific excellence, recognizing significant long-term contributions to the understanding, treatment, or prevention of diabetes. Philipp E. Scherer, PhD, of the Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, TX, received the prestigious award at the ADA's 75th Scientific Sessions, 5-9 June 2015, in Boston, MA...
June 2016: Diabetes
https://www.readbyqxmd.com/read/27150388/hba1c-measurements-across-different-platforms-exercising-caution-when-making-decisions-regarding-diagnosis
#17
J Cao, D Li, M Steffes, M D Bellin
In 2010, the American Diabetes Association (ADA) endorsed whole-blood HbA1c as a diagnostic test for diabetes mellitus, and selected 6.5% asthe diagnostic criterion for diabetes, and 5.7-6.4% as prediabetes [1]. Implementing this diagnostic standard requires the clinician to assume that HbA1c results are more-or-less equivalent regardless of the methodology employed; however, we were recently faced with the limitation of such an assumption at our institution. In early 2015, HbA1c values were simultaneously measured in five consecutive islet autotransplant recipients on no or low-dose insulin in both a research central laboratory [a secondary reference laboratory for the National Glycohemoglobin Standardization Program (NGSP)] using cation exchange high-performance liquid chromatography (HPLC) on Tosoh G8 (Tosoh Bioscience, Tokyo, Japan) and in our hospital's central chemistry laboratory using immunoassay (Dimension Vista 1500; Siemens Health Diagnostics, Erlangen, Germany)...
May 6, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/26946699/-news-in-diabetology-2015
#18
François R Jornayvaz
The year 2015 was punctuated by numerous events in diabetology. First, the ADA/EASD guidelines have been updated. The pharmacological panel for type 2 diabetes treatment saw the arrival of different new molecules. Two new basal insulins were also approved. Also, cardiovascular safety trials have been published regarding recent antidiabetic drugs. A new insulin pump than can be coupled with a glucosensor was released. Finally, a new unexpected complication of SGLT2 inhibitors treatment was reported, the euglycemic keto-acidosis...
January 13, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/26912968/making-a-meaningful-difference-learning-from-people-practice-and-research
#19
Linda M Delahanty
This article is adapted from the address Ms. Delahanty delivered as the recipient of the American Diabetes Association's (ADA) Outstanding Educator in Diabetes Award for 2015. She delivered the address in June 2015 at the Association's 75th Scientific Sessions in Boston, Mass. A webcast of this speech is available for viewing at the ADA website (http://professional.diabetes.org/webcasts).
February 2016: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/26912967/diabetes-care-and-research-what-should-be-the-next-frontier
#20
David G Marrero
This article is adapted from the address of the American Diabetes Association (ADA) President, Health Care and Education, given in June 2015 at the Association's 75th Scientific Sessions in Boston, Mass. A webcast of this speech is available for viewing at the ADA website (http://professional.diabetes.org/webcasts).
February 2016: Diabetes Spectrum: a Publication of the American Diabetes Association
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