Teresa Liu-Ambrose, Elizabeth Dao, Rachel A Crockett, Cindy K Barha, Ryan S Falck, John R Best, Ging-Yeuk R Hsiung, Thalia S Field, Kenneth M Madden, Walid A Alkeridy, Narlon C Boa Sorte Silva, Jennifer C Davis, Lisanne F Ten Brinke, Stephanie Doherty, Roger C Tam
BACKGROUND: Subcortical ischemic vascular cognitive impairment (SIVCI) is the most common form of vascular cognitive impairment. Importantly, SIVCI is considered the most treatable form of cognitive impairment in older adults, due to its modifiable risk factors such as hypertension, diabetes mellitus, and hypercholesterolemia. Exercise training is a promising intervention to delay the progression of SIVCI, as it actively targets these cardiometabolic risk factors. Despite the demonstrated benefits of resistance training on cognitive function and emerging evidence suggesting resistance training may reduce the progression of white matter hyperintensities (WMHs), research on SIVCI has predominantly focused on the use of aerobic exercise...
March 18, 2021: Trials