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JOURNAL ARTICLE
Ada Wai Tung Fung, Allen Ting Chun Lee, Suk Ling Ma, Linda Chiu Wa Lam
BACKGROUND: Early cognitive deficits commonly seen in older people have not been well defined and managed in primary care. The objectives are (1) to develop and validate a new risk score to estimate the risk of dementia in Chinese older population; and (2) to evaluate the use of risk score in conjunction with cognitive screening in detecting early cognitive deficits in community older people. METHODS: A development cohort of 306 cognitive healthy older adults aged 60 or above were followed for 6 years...
March 21, 2024: BMC Geriatrics
#22
JOURNAL ARTICLE
Daniel J Battillo, Mary-Margaret E Remchak, Ankit M Shah, Steven K Malin
CONTEXT: Relative hypoglycemia (RH) is linked to sympathetic responses that can alter vascular function in individuals with type 2 diabetes. However, less is known about the role of RH on hemodynamics or metabolic insulin sensitivity in prediabetes. OBJECTIVE: Determine if RH alters peripheral endothelial function or central hemodynamics to a greater extent in those with prediabetes (PD) versus normoglycemia (NG). METHODS: Seventy adults with obesity were classified using ADA criteria as PD (n=34 (28F); HbA1c=6...
March 16, 2024: Journal of Clinical Endocrinology and Metabolism
#23
JOURNAL ARTICLE
Shanzay Haider, Melissa M Parker, Elbert S Huang, Richard W Grant, Howard H Moffet, Neda Laiteerapong, Rajesh K Jain, Jennifer Y Liu, Kasia J Lipska, Andrew J Karter
BACKGROUND: To examine the willingness of older patients to take less diabetes medication (de-intensify) and to identify characteristics associated with willingness to de-intensify treatment. METHODS: Survey conducted in 2019 in an age-stratified, random sample of older (65-100 years) adults with diabetes on glucose-lowering medications in the Kaiser Permanente Northern California Diabetes Registry. We classified survey responses to the question: "I would be willing to take less medication for my diabetes" as willing, neutral, or unwilling to de-intensify...
March 12, 2024: Journal of the American Geriatrics Society
#24
JOURNAL ARTICLE
Hongyi Yang, Maobin Kuang, Jiajun Qiu, Shiming He, Changhui Yu, Guotai Sheng, Yang Zou
BACKGROUND: Prediabetes is a high-risk state for diabetes, and numerous studies have shown that the body mass index (BMI) and triglyceride-glucose (TyG) index play significant roles in risk prediction for blood glucose metabolism. This study aims to evaluate the relative importance of BMI combination with TyG index (TyG-BMI) in predicting the recovery from prediabetic status to normal blood glucose levels. METHODS: A total of 25,397 prediabetic subjects recruited from 32 regions across China...
March 8, 2024: Lipids in Health and Disease
#25
JOURNAL ARTICLE
Smriti Rastogi, Narsingh Verma, Gourav S Raghuwanshi, Virendra Atam, Dileep Kumar Verma
AIMS: This study aimed to investigate the impact of time-restricted meal intake (TRM) on anthropometric and biochemical parameters in patients with type 2 diabetes mellitus (T2DM). METHODS: A total of 400 patients diagnosed with T2DM were selected from the Endocrinology Department at King George's Medical University (KGMU), Lucknow, based on the American Diabetes Association (ADA) guidelines and specific criteria. A total of 127 patients were lost to follow-up, resulting in 273 patients who completed the study...
February 2024: Curēus
#26
JOURNAL ARTICLE
Yohhei Hamada, Matteo Quartagno, Irwin Law, Farihah Malik, Frank Adae Bonsu, Ifedayo M O Adetifa, Yaw Adusi-Poku, Umberto D'Alessandro, Adedapo Olufemi Bashorun, Vikarunnessa Begum, Dina Bisara Lolong, Tsolmon Boldoo, Themba Dlamini, Simon Donkor, Bintari Dwihardiani, Saidi Egwaga, Muhammad N Farid, Anna Marie Celina G Garfin, Donna Mae G Gaviola, Mohammad Mushtuq Husain, Farzana Ismail, Mugagga Kaggwa, Deus V Kamara, Samuel Kasozi, Kruger Kaswaswa, Bruce Kirenga, Eveline Klinkenberg, Zuweina Kondo, Adebola Lawanson, David Macheque, Ivan Manhiça, Llang Bridget Maama-Maime, Sayoki Mfinanga, Sizulu Moyo, James Mpunga, Thuli Mthiyane, Dyah Erti Mustikawati, Lindiwe Mvusi, Hoa Binh Nguyen, Hai Viet Nguyen, Lamria Pangaribuan, Philip Patrobas, Mahmudur Rahman, Mahbubur Rahman, Mohammed Sayeedur Rahman, Thato Raleting, Pandu Riono, Nunurai Ruswa, Elizeus Rutebemberwa, Mugabe Frank Rwabinumi, Mbazi Senkoro, Ahmad Raihan Sharif, Welile Sikhondze, Charalambos Sismanidis, Tugsdelger Sovd, Turyahabwe Stavia, Sabera Sultana, Oster Suriani, Albertina Martha Thomas, Kristina Tobing, Martie Van der Walt, Simon Walusimbi, Mohammad Mostafa Zaman, Katherine Floyd, Andrew Copas, Ibrahim Abubakar, Molebogeng X Rangaka
Tuberculosis (TB) and non-communicable diseases (NCD) share predisposing risk factors. TB-associated NCD might cluster within households affected with TB requiring shared prevention and care strategies. We conducted an individual participant data meta-analysis of national TB prevalence surveys to determine whether NCD cluster in members of households with TB. We identified eligible surveys that reported at least one NCD or NCD risk factor through the archive maintained by the World Health Organization and searching in Medline and Embase from 1 January 2000 to 10 August 2021, which was updated on 23 March 2023...
2024: PLOS Glob Public Health
#27
REVIEW
Eleni Rebelos, Ioanna A Anastasiou, Anastasios Tentolouris, Nikolaos Papanas, Edward Jude
Diabetic neuropathy is a common complication of diabetes; yet its pathophysiology is still incompletely understood and until today, there is no specific treatment against it. In the two 2023 large congresses on diabetes (American Diabetes Association, ADA, European Association for the Study of Diabetes, EASD), several high-level studies have been presented. They have attempted to delineate the pathophysiology of DN, the characteristics of affected patients, and future potential treatments. We herein review the presented studies on diabetic neuropathy at these diabetes congresses and discuss the needs for future research on this topic...
February 28, 2024: International Journal of Lower Extremity Wounds
#28
JOURNAL ARTICLE
Ainur Donayeva, Ainur Amanzholkyzy, Ibrahim Abdelazim, Meirambek Kurmangazin, Zaituna Khamidullina, Madina Kurmanalina, Aigul Sumanova, Zhanara Shabanbayeva, Zhenisbek Baubekov, Bauyrzhan Bissaliyev, Gulnara Gubasheva, Ihab Samaha
Vitamin D receptor (VDR) expression in the female reproductive tract explains the regulatory role of vitamin D on inflammatory cytokine and prostaglandin (PGD) synthesis. This study aimed to evaluate the effect of vitamin D on adolescents' primary dysmenorrhea and the relationship between Vit. D and adolescents' primary dysmenorrhea. Eighty-five adolescents were included in the current study. After a detailed evaluation, pelvic sonography was performed for all participants to rule out any pelvic pathology. Blood samples were collected to measure thyroid stimulating hormone (TSH), prolactin, glycosylated hemoglobin (HbA1C), and 25-hydroxyvitamin D (25[OH]D)...
November 2023: Journal of Medicine and Life
#29
JOURNAL ARTICLE
Nasser Aljehani, Suliman Alghnam, Ada Alqunaibet, Shehana Alwahabi, Husein Reka, Rimah Almohammed, Abdullah Almaghrabi, Shabab Alghamdi
BACKGROUND: Noncommunicable diseases (NCDs) are a leading threat to population health in Saudi Arabia. Addressing NCDs is a priority for health-care transformation, and understanding the current disease prevalence is crucial. The prevalence in other settings is unknown because studies have relied on data from households or public health-care institutions. This study aims to investigate the prevalence and predictors of diabetes in the privately insured population. MATERIALS AND METHODS: This retrospective study explored the prevalence and predictors of diabetes in beneficiaries aged 15 years or older who sought medical care in 2022...
2024: Journal of Family & Community Medicine
#30
REVIEW
Joseph Henson, Alix Covenant, Andrew P Hall, Louisa Herring, Alex V Rowlands, Thomas Yates, Melanie J Davies
For the first time, the latest American Diabetes Association/European Association for the Study of Diabetes (ADA/EASD) consensus guidelines have incorporated a growing body of evidence linking health outcomes associated with type 2 diabetes to the movement behavior composition over the whole 24-h day. Of particular note, the importance of sleep as a key lifestyle component in the management of type 2 diabetes is promulgated and presented using three key constructs: quantity, quality, and timing (i.e., chronotype)...
March 1, 2024: Diabetes Care
#31
JOURNAL ARTICLE
Milagros Fanny Vera Castro, Charles Elias Assmann, Karine Paula Reichert, Priscila Marquezan Coppetti, Naiara Stefanello, Aniélen Dutra da Silva, Vitor Bastianello Mostardeiro, Loren Borba de Jesus, Marcylene Vieira da Silveira, Adriel Antonio Schirmann, Mateus Fracasso, Roberto Marinho Maciel, Vera Maria Melchiors Morsch, Maria Rosa Chitolina Schetinger
This study evaluated the effect of vitamin D3 (VIT D3 ) supplementation on the enzymatic activities and density of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase), ecto-5-nucleotidase (E-5'-NT), adenosine deaminase (ADA), as well as the density of P2 × 7R, P2Y12R, A1R, A2AR receptors, IL-1β, and oxidative parameters in type 2 diabetic rats. Forty male Wistar rats were fed a high carbohydrate-high fat diet (HCHFD) and received an intraperitoneal injection containing a single dose of streptozotocin (STZ, 35 mg/kg)...
February 17, 2024: Journal of Nutritional Biochemistry
#32
Maria Ada Corich, Michele Niero, Lucia Corich, Elisabetta Ferretti, Paolo De Colle, Stella Bernardi, Giuliano Ceschia, Gianfranco Sanson, Michela Zanetti
BACKGROUND: Coronavirus disease 2019 (COVID-19) has an important impact on the kidney through direct and indirect damage mechanisms. Most previous studies have highlighted lesions caused by this virus in the early segments of the nephron. However, due to the antigenic characteristics of the virus, with almost ubiquitous receptors, and the molecular release it triggers, the distal segments of the nephron could also be affected. METHODS: A 71 year-old-man with respiratory failure while suffering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia presented with typical symptoms of diabetes insipidus after ~20 days of hospitalization...
2024: Access microbiology
#33
JOURNAL ARTICLE
Megan Champion, Gabriel Wills Avila, Angelica E Garcia, Faviola M Álvarez Delgado, Connie A Valdez
BACKGROUND: An FQHC in Denver, Colorado developed and implemented an interprofessional care model to collaboratively manage type 2 diabetes mellitus (T2DM). Utilizing the 340B program, the team protocolized ADA Guidelines to promote the early adoption of first-line medications, glucagon-like peptide1 receptor agonists (GLP1 RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) to improve patient outcomes. OBJECTIVES: To assess the impact of interprofessional collaborative management versus standard care on early initiation of a SGLT2i and/or GLP1 RA as first-line therapies to enhance (1) deprescribing of insulin, (2) reducing overbasalization of insulin through insulin de-escalation, and (3) effectively lowering A1C levels in adult primary care patients with T2DM...
2024: Journal of Primary Care & Community Health
#34
JOURNAL ARTICLE
Mengesh Akale, Tirhas Tadesse, Balew Arega
BACKGROUND: Comprehensive high quality of care is critical in preventing diabetic complications and improving quality of life. This needs compliance with guidelines and focused therapy. There is no data in Ethiopia evaluating the quality of diabetes care using standard guidelines (American diabetic association and international diabetic federation) as a reference. METHODS: A cross-sectional study was conducted at Yekatit 12 Hospital Medical College (YHMC) to assess the process and outcome quality indicators of diabetic patients...
2024: Diabetes, Metabolic Syndrome and Obesity
#35
JOURNAL ARTICLE
Muhammad Adnan, Muhammad Aasim
BACKGROUND: A variety of screening tools and criteria are used for the diagnosis of gestational diabetes mellitus (GDM). As a result, the prevalence rate of GDM varied from 4.41% to 57.90% among studies from Pakistan. Beside this disagreement, similar multi-centric studies, community surveys and pooled evidence were lacking from the country. Therefore, this first systematic review and meta-analysis aimed to measure the overall and subgroup pooled estimates of GDM and explore the methodological variations among studies for any inconsistency...
February 3, 2024: BMC Pregnancy and Childbirth
#36
JOURNAL ARTICLE
Anna K Forbes, William Hinton, Michael D Feher, William Elson, Mark Joy, José M Ordóñez-Mena, Xuejuan Fan, Nicholas I Cole, Debasish Banerjee, Rebecca J Suckling, Simon de Lusignan, Pauline A Swift
BACKGROUND: The cardiovascular and kidney benefits of sodium-glucose co-transporter-2 (SGLT2) inhibitors in people with chronic kidney disease (CKD) are well established. The implementation of updated SGLT2 inhibitor guidelines and prescribing in the real-world CKD population remains largely unknown. METHODS: A cross-sectional study of adults with CKD registered with UK primary care practices in the Oxford-Royal College of General Practitioners Research and Surveillance Centre network on the 31st December 2022 was undertaken...
February 2024: EClinicalMedicine
#37
JOURNAL ARTICLE
Reyof Aljuhani, Merna Adas, Raghad Alnaami, Reham Alshehri, Rahaf Alqarni, Sundus NoorSaeed, Abdulmoein Al-Agha
Objectives We aimed to determine the benefits and drawbacks of real-time continuous glucose monitoring (rtCGM) compared with those of self-monitoring of blood glucose (SMBG) in children and adolescents with type 1 diabetes (T1D) and their impact on glycemic control, hypo- and hyperglycemic episodes, exercise, quality of life, and psychosocial factors. Methodology This quantitative, comparative, cross-sectional study was conducted between July 2022 and March 2023 at the Pediatric Endocrine Outpatient Clinic, King Abdulaziz University Hospital, Saudi Arabia...
January 2024: Curēus
#38
JOURNAL ARTICLE
Mario B Prado, Karen Joy B Adiao
BACKGROUND: Current medications for diabetic neuropathy (DN) recommended by ADA and AAN don't address the pathologic process of denervation among DN patients, hence ancillary treatments such as reactive oxygen scavengers (ROS) may be needed. The purpose of this paper is to summarize the available evidence about the efficacy and safety of alpha-lipoic acid (ALA) and gamma-linolenic acid (GLA) in the management of DN. METHODS: Using the search terms [(alpha lipoic acid or ALA or thioctic acid or thioctacid) or (gamma linolenic acid or GLA)] AND [(Diabetes or Diabetes Mellitus) AND (polyneuropathy or neuropathy or sensorimotor polyneuropathy or radiculopathy)], 11 studies were included in this review and combined meta-analysis...
January 29, 2024: Canadian Journal of Diabetes
#39
JOURNAL ARTICLE
David Rebus, Andrew Iskander, Felicia Deonarine, Asad Almas, Darren Rattigan, Patrick Henn, Kayode Philip Fadahunsi, John O'Donoghue
BACKGROUND: Diabetes is among the most common chronic conditions people live with across the world. While it can be managed to a substantial degree, it can result in significant complications. As such, easy access to accurate tools to aid diabetes management is useful in minimizing these complications. Mobile apps are highly accessible and widely used, but there is a gap in the literature examining their compliance with medical guidelines. OBJECTIVE: The aims of this study are to develop the Analysis of Diabetes Apps (ADA) checklist to evaluate apps' compliance to guidelines set by the International Diabetes Federation (IDF) on the treatment and management of type 2 diabetes; to assess type 2 diabetes apps in the Apple App Store and the Android Google Play Store, and their compliance with international guidelines using the ADA framework; and to compare the novel ADA checklist against both the Mobile App Rating Scale (MARS) tool kit and app ratings for each store...
January 31, 2024: JMIR Research Protocols
#40
JOURNAL ARTICLE
Jan Tuzon, David C Mulkey
BACKGROUND: Uncontrolled blood glucose may lead to serious complications in patients with type two diabetes mellitus (T2DM). Patients may not have the support, motivation, or encouragement to adhere to the lifestyle changes necessary to control their T2DM. LOCAL PROBLEM: More than 75% of the primary care clinic's patients are diagnosed with T2DM, with most patients at the practice site having an average hemoglobin A1c (HbA1c) level of 8.5%. The primary care clinic did not use text messaging to disseminate diabetes self-management education and support (DSMES) as outlined in Standard 4 of the American Diabetic Association's (ADA) clinical practice guideline...
January 31, 2024: Journal of the American Association of Nurse Practitioners
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