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https://www.readbyqxmd.com/read/27904566/the-characteristics-of-pre-diabetic-patients-associated-with-body-composition-and-cardiovascular-disease-risk-factors-in-the-iranian-population
#1
Zahra Gholi, Motahar Heidari-Beni, Awat Feizi, Bijan Iraj, Gholamreza Askari
BACKGROUND: Different populations have shown various patterns of association between impaired fasting glucose (IFG) and body composition parameters and risk factors of cardiovascular disease (CVD). The current study aimed at investigating the differences between persons with prediabetes and healthy people in terms of CVD risk factors including body composition parameters, blood pressure, and lipid profile in a sample of the Iranian population. MATERIALS AND METHODS: In a case-control setting, a sample containing 386 (193 prediabetic subjects and 193 normal subjects) of the first-degree relatives of diabetic patients aged 35-55 years were investigated...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27899314/preeclampsia-and-the-risk-of-cataract-extraction-in-life
#2
Nathalie Auger, Marc-André Rhéaume, Gilles Paradis, Jessica Healy-Profitós, Ada Hsieh, William D Fraser
BACKGROUND: Pregnancy-related risk factors for cataract are understudied, including the possibility that preeclampsia increases the risk of cataract later in life. OBJECTIVE: To evaluate the long term risk of cataract extraction following a preeclamptic pregnancy STUDY DESIGN: We carried out a historic cohort study of 1,108,541 women who delivered at least one infant in any hospital in the province of Quebec, Canada between 1989 and 2013, including 64,350 with preeclampsia and 5,732 with cataract extractions...
November 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27881363/association-between-prediabetes-and-risk-of-cardiovascular-disease-and-all-cause-mortality-systematic-review-and-meta-analysis
#3
Yuli Huang, Xiaoyan Cai, Weiyi Mai, Meijun Li, Yunzhao Hu
OBJECTIVES:  To evaluate associations between different definitions of prediabetes and the risk of cardiovascular disease and all cause mortality. DESIGN:  Meta-analysis of prospective cohort studies. DATA SOURCES:  Electronic databases (PubMed, Embase, and Google Scholar). SELECTION CRITERIA:  Prospective cohort studies from general populations were included for meta-analysis if they reported adjusted relative risks with 95% confidence intervals for associations between the risk of composite cardiovascular disease, coronary heart disease, stroke, all cause mortality, and prediabetes...
November 23, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27879353/2016-health-care-education-presidential-address-if-dsme-were-a-pill-would-you-prescribe-it
#4
Margaret A Powers
This address was delivered by Margaret A. Powers, PhD, RD, CDE, President, Health Care & Education, of the American Diabetes Association (ADA), at the ADA's 76th Scientific Sessions in New Orleans, LA, on 11 June 2016. Dr. Powers conducts research and has a clinical practice as a registered dietitian and diabetes educator at the International Diabetes Center at Park Nicollet in Minneapolis. Her research focuses on improving diabetes outcomes including factors that affect the clinical, psychosocial, and behavioral aspects of diabetes...
December 2016: Diabetes Care
https://www.readbyqxmd.com/read/27877071/the-sweet-spots-study-a-real-world-interpretation-of-the-2012-american-diabetes-association-position-statement-regarding-individualized-a1c-targets
#5
Nella Bieszk, Michael Grabner, Wenhui Wei, Nicole G Bonine, Judith J Stephenson
OBJECTIVE: To evaluate awareness of the 2012 American Diabetes Association (ADA) Position Statement among physicians and assess its effects on patient-centered glycated hemoglobin (A1C) goals in the management of type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: The Summarizing Real-World Individualized TrEatmEnT GoalS and Potential SuppOrT Systems in Type 2 Diabetes (SWEET SPOTS) study used the HealthCore claims database to identify T2D patients, stratified by risk, and their treating physicians to assess primary care physician and endocrinologist awareness of the 2012 ADA Position Statement...
2016: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/27870552/glycemic-predictors-of-insulin-independence-after-total-pancreatectomy-with-islet-auto-transplantation
#6
Michael Quartuccio, Erica Hall, Vikesh Singh, Martin A Makary, Kenzo Hirose, Niraj Desai, Christi Walsh, Daniel Warren, Zhaoli Sun, Ellen Stein, Rita R Kalyani
CONTEXT: Total pancreatectomy with islet auto transplantation (TPIAT) is a treatment for medically refractory chronic pancreatitis that can prevent postsurgical diabetes in a subset of patients. Predictors of insulin independence are needed for appropriate patient selection and counseling. OBJECTIVE: To explore glycemic predictors of insulin independence after TPIAT. DESIGN: A prospective cohort of patients undergoing TPIAT from 2011-2016...
November 21, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27863979/comparative-prognostic-performance-of-definitions-of-prediabetes-a-prospective-cohort-analysis-of-the-atherosclerosis-risk-in-communities-aric-study
#7
Bethany Warren, James S Pankow, Kunihiro Matsushita, Naresh M Punjabi, Natalie R Daya, Morgan Grams, Mark Woodward, Elizabeth Selvin
BACKGROUND: No consensus on definitions of prediabetes exists among international organisations. Analysis of associations with different definitions and clinical complications can inform the comparative value of different prediabetes definitions. We compared the risk of future outcomes across different prediabetes definitions based on fasting glucose concentration, HbA1c, and 2 h glucose concentration during over two decades of follow-up in the community-based Atherosclerosis Risk in Communities (ARIC) study...
November 15, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27859570/diabetes-incidence-and-prevalence-in-hong-kong-china-during-2006-2014
#8
J Quan, T K Li, H Pang, C H Choi, S C Siu, S Y Tang, N M Wat, J Woo, J M Johnston, G M Leung
AIMS: To estimate recent secular changes in the incidence and prevalence of diabetes and pre-diabetes among Hong Kong Chinese adults, and thus show possible future trends for developing mainland China. METHODS: Based on a complete census of the public sector health records of 6.4 million people from 2006 to 2014, diabetes cases were ascertained using different methods including the World Health Organization (WHO) 2011 guidelines (HbA1c , fasting plasma glucose and glucose tolerance test), American Diabetes Association (ADA) 2015 guidelines (plus random plasma glucose), and additionally recorded diagnosis codes and medication dispensation...
November 12, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27832749/type-2-diabetes-compromises-the-value-of-non-invasively-measured-augmentation-index-in-predicting-the-severity-of-coronary-artery-disease-a-hospital-based-observational-study
#9
Sijing Wu, Yujie Zhou, Yueping Li, Yuyang Liu, Dongmei Shi, Xiaoli Liu, Wei Liu, Yi Yu, Shuo Jia
BACKGROUND: Central hemodynamic indices have been demonstrated to correlate with coronary artery disease (CAD). However, in the context of type 2 diabetes mellitus (DM), this correlation has not been fully illustrated. Therefore, this study was employed to investigate the impact of DM on the correlation between aortic augmentation index and the severity of coronary artery disease. METHODS: In this study, we analyzed 197 patients who underwent coronary angiography at Anzhen Hospital from September 2015 to January 2016...
November 10, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27792698/-prevalence-of-impaired-fasting-glucose-in-a-working-population-of-spanish-mediterranean-area-influence-of-sociodemographic-variables-and-healthy-habits
#10
Ángel Arturo López-González, Zoe Manzanero, Ma Teófila Vicente-Herrero, Sheila García-Agudo, María Gil-Llinás, Francisco Moreno-Morcillo
INTRODUCTION: The impaired fasting glucose (IFG) is an intermediate clinical situation between normal glucose and type 2 diabetes, it is known that 25% of people with IFG progress to type 2 diabetes. METHODS: Descriptive study in 60,798 Spanish workers. The IFG was determined using the American Diabetes Association (ADA) criteria: 100-125 mg/dl and the World Health Organization (WHO) criteria: 110-125 mg/dl. The influence of sociodemographic variables (age, sex, social class, studies class) and healthy habits (tobacco, alcohol consumption, physical activity, feeding) were evaluated in the IFG prevalence...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27788477/effect-of-dietary-supplementation-of-padauk-pterocarpus-soyauxii-leaf-on-high-fat-diet-streptozotocin-induced-diabetes-in-rats-brain-and-platelets
#11
Jamiyu A Saliu, Ganiyu Oboh, Olasunkanmi S Omojokun, João B T Rocha, Maria R Schetinger, Jessie Guterries, Naiara Stefanello, Fabiano Carvalho, Roberta Schmatz, Vera M Morsch, Aline Boligon
BACKGROUND: This study investigated the effects of Padauk leaf on brain malondialdehyde (MDA) content, acetylcholinesterase (AChE) activities, ectonucleotidases and adenosine deaminase (ADA) activities in the platelet of high fat diet and streptozotocin (STZ)-induced diabetic rats. METHODS: The animals were divided into six groups (n=7): normal control rats; diabetic rats+high fat diet (HFD); diabetic rats+HFD+Metformin; diabetic rats+HFD+acarbose; diabetic rats+HFD+10% Padauk leaf; normal rats+basal diet+10% Padauk leaf...
October 24, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27761942/effects-of-advanced-carbohydrate-counting-guided-by-an-automated-bolus-calculator-in-type-1-diabetes-mellitus-stenoabc-a-12-month-randomized-clinical-trial
#12
E Hommel, S Schmidt, D Vistisen, K Neergaard, M Gribhild, T Almdal, K Nørgaard
AIMS: To test whether concomitant use of an automated bolus calculator for people with Type 1 diabetes carrying out advanced carbohydrate counting would induce further improvements in metabolic control. METHODS: We conducted a 12-month, randomized, parallel-group, open-label, single-centre, investigator-initiated clinical study. We enrolled advanced carbohydrate counting-naïve adults with Type 1 diabetes and HbA1c levels 64-100 mmol/mol (8.0-11.3%), who were receiving multiple daily insulin injection therapy...
October 20, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27761351/metabolic-control-in-patients-with-type-2-diabetes-mellitus-in-a-public-hospital-in-peru-a-cross-sectional-study-in-a-low-middle-income-country
#13
Irma Elizabeth Huayanay-Espinoza, Felix Guerra-Castañon, María Lazo-Porras, Ana Castaneda-Guarderas, Nimmy Josephine Thomas, Ana-Lucia Garcia-Guarniz, Augusto A Valdivia-Bustamante, Germán Málaga
OBJECTIVE: The objective of this study was to assess patients' achievement of ADA (American Diabetes Association) guideline recommendations for glycosylated hemoglobin, lipid profile, and blood pressure in a type 2 diabetes mellitus (T2DM) outpatient clinic in a low-middle income country (LMIC) setting. METHODS: This is a descriptive cross-sectional study with 123 ambulatory T2DM patients who are being treated at a public hospital in Lima, Peru. Data was gathered via standardized interviews, clinical surveys, and anthropomorphic measurements for each patient...
2016: PeerJ
https://www.readbyqxmd.com/read/27754018/js-ksh-jsh-chl-01-1-cardio-metabolic-risks-in-hypertension-are-we-different-from-western-societies
#14
Hiroshi Itoh
Many hypertension guidelines have been published mainly from Western countries to standardize the management of hypertension all over the world, however, the significance of hypertension, along with other cardio-metabolic risks, such as obesity, diabetes or dyslipidemia should differ among different races. This paper compares the relevance of hypertension, one of the most important cardio-metabolic risk factors, in Asian and Western societies.1) Low target level of blood pressure control for diabetic hypertensives in JapanIn the Japanese Society of Hypertension Guidelines for the management of Hypertension (JSH2014), the target of blood pressure (BP) control in hypertensive patients with diabetes was set as < 130/80 mmHg...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753885/ish-ada-06-intima-media-thickness-of-the-carotid-bulb-is-associated-with-worsening-of-orthostatic-hypotension-in-patients-with-metabolic-disorder
#15
Yusuke Kobayashi, Hideo Kobayashi, Hiroaki Ishiguro, Keisuke Yatsu, Tetsuya Fujikawa, Satoshi Umemura
OBJECTIVE: Though both carotid bulb and aortic arch are known to play important roles in regulation of blood pressure through modulation in baroreflex function, few studies have investigated the association of carotid bulb atherosclerosis and large arterial stiffness and orthostatic blood pressure change. DESIGN AND METHOD: Patients with metabolic disorder such as hypertension, dyslipidemia and diabetes mellitus underwent measurement of segment-specific carotid intima-media thickness (IMT) (as an index of atherosclerosis of carotid bulb), cardio-ankle vascular index (CAVI) (as an index for large arterial stiffness), heart rate variability (HRV) (as an index of baroreflex function) and sit-to-stand orthostatic blood pressure change (as a simple method for detecting orthostatic hypotension)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27752328/correlation-of-global-risk-assessment-with-cardiovascular-complications-in-patients-with-diabetes-mellitus-living-in-puerto-rico
#16
Efraín Rodríguez-Vigil, Migdalia Rodríguez-Chacón, José J Ruiz Valcarcel
OBJECTIVE: The objective of this study was to assess the current relationship between certain demographics and chemical factors, and the risk of cardiovascular complications, within a Puerto Rican population with diabetes mellitus. RESEARCH DESIGN AND METHODS: A total of 2075 patients with diabetes mellitus were retrospectively evaluated to determine the influence of certain demographics and chemical variables on the appearance of cardiovascular complications. A group of demographic and laboratory variables were analyzed...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27733159/moderate-intensity-statin-therapy-seems-ineffective-in-primary-cardiovascular-prevention-in-patients-with-type-2-diabetes-complicated-by-nephropathy-a-multicenter-prospective-8%C3%A2-years-follow-up-study
#17
Ferdinando Carlo Sasso, Nadia Lascar, Antonella Ascione, Ornella Carbonara, Luca De Nicola, Roberto Minutolo, Teresa Salvatore, Maria Rosaria Rizzo, Plinio Cirillo, Giuseppe Paolisso, Raffaele Marfella
BACKGROUND: Although numerous studies and metanalysis have shown the beneficial effect of statin therapy in CVD secondary prevention, there is still controversy such the use of statins for primary CVD prevention in patients with DM. The purpose of this study was to evaluate the occurrence of total major adverse cardio-vascular events (MACE) in a cohort of patients with type 2 diabetes complicated by nephropathy treated with statins, in order to verify real life effect of statin on CVD primary prevention...
October 13, 2016: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/27694000/neuroprotective-effects-of-quercetin-on-memory-and-anxiogenic-like-behavior-in-diabetic-rats-role-of-ectonucleotidases-and-acetylcholinesterase-activities
#18
Roberto M Maciel, Fabiano B Carvalho, Ayodeji A Olabiyi, Roberta Schmatz, Jessié M Gutierres, Naiara Stefanello, Daniela Zanini, Michelle M Rosa, Cinthia M Andrade, Maribel A Rubin, Maria Rosa Schetinger, Vera Maria Morsch, Cristiane C Danesi, Sonia T A Lopes
The present study investigated the protective effect of quercetin (Querc) on memory, anxiety-like behavior and impairment of ectonucleotidases and acetylcholinesterase (AChE) activities in brain of streptozotocin-induced diabetic rats (STZ-diabetes). The type 1 diabetes mellitus was induced by an intraperitoneal injection of 70mg/kg of streptozotocin (STZ), diluted in 0.1M sodium-citrate buffer (pH 4.5). Querc was dissolved in 25% ethanol and administered by gavage at the doses of 5, 25 and 50mg/kg once a day during 40days...
September 29, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27660696/evidence-for-current-diagnostic-criteria-of-diabetes-mellitus
#19
REVIEW
Ritesh Kumar, Lakshmana Perumal Nandhini, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Muthupillai Vivekanadan
Diabetes mellitus is a non-communicable metabolic derangement afflicting several millions of individuals globally. It is associated with several micro and macrovascular complications and is also a leading cause of mortality. The unresolved issue is that of definition of the diagnostic threshold for diabetes. The World Health Organization and the American Diabetes Association (ADA) have laid down several diagnostic criteria for diagnosing diabetes and prediabetes based on the accumulating body of evidence.This review has attempted to analyse the scientific evidence supporting the justification of these differing criteria...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27660119/2016-presidential-address-diabetes-at-212%C3%A2-confronting-the-invisible-disease
#20
Desmond Schatz
This address was delivered by Desmond Schatz, MD, President, Medicine & Science, of the American Diabetes Association (ADA), at the Association's 76th Scientific Sessions in New Orleans, LA, on 12 June 2016. Dr. Schatz is Professor and Associate Chairman of Pediatrics, Medical Director of the University of Florida Diabetes Institute, and Director of the Clinical Research Center at the University of Florida, Gainesville, FL. A physician-scientist, he has been involved in type 1 diabetes research since the mid-1980s and has published over 300 articles and book chapters...
October 2016: Diabetes Care
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