keyword
https://read.qxmd.com/read/38650792/impact-of-clinical-and-sociodemographic-factors-on-quality-of-life-following-coronary-artery-bypass-grafting-a-mixed-methods-study
#1
JOURNAL ARTICLE
Abdulmajeed A Alzahrani, Abdullah K AlAssiri, Khalid E Al-Ebrahim, Zeyad T Ganbou, Meshal M Alsudais, Abdulmajeed M Khafagy
INTRODUCTION: Coronary artery bypass grafting (CABG) is an essential surgical management modality for patients with coronary artery disease. Health-related quality of life (HRQoL) has become important because of the significant decrease in the mortality rate associated with CABG. We aimed to explore the factors that affect the quality of life after CABG. METHODS: This study used a descriptive correlational design to assess the determinants of HRQoL using the 36-item Short Form Health Survey questionnaire (SF-36)...
March 2024: Curēus
https://read.qxmd.com/read/38646481/association-of-rotating-night-shift-work-with-tooth-loss-and-severe-periodontitis-among-permanent-employees-in-japan-a-cross-sectional-study
#2
JOURNAL ARTICLE
Yukihiro Sato, Eiji Yoshioka, Yasuaki Saijo
BACKGROUND: The modern 24/7 society demands night shift work, which is a possible risk factor for chronic diseases. This study aimed to examine the associations of rotating night shift work duration with tooth loss and severe periodontitis. METHODS: This cross-sectional study used data from a self-administered questionnaire survey conducted among 3,044 permanent employees aged 20-64 years through a Japanese web research company in 2023. The duration of rotating night shift work was assessed using a question from the Nurses' Health Study...
2024: PeerJ
https://read.qxmd.com/read/38643977/a-protocol-for-the-conduct-of-a-multicentre-prospective-randomized-superiority-trial-of-surgical-versus-non-surgical-interventions-for-humeral-shaft-fractures
#3
JOURNAL ARTICLE
Marloes Franssen, Juul Achten, Duncan Appelbe, Matthew L Costa, Susan Dutton, James Mason, Jenny Gould, Andrew Gray, Amar Rangan, Warren Sheehan, Harvinder Singh, Stephen E Gwilym
AIMS: Fractures of the humeral shaft represent 3% to 5% of all fractures. The most common treatment for isolated humeral diaphysis fractures in the UK is non-operative using functional bracing, which carries a low risk of complications, but is associated with a longer healing time and a greater risk of nonunion than surgery. There is an increasing trend to surgical treatment, which may lead to quicker functional recovery and lower rates of fracture nonunion than functional bracing. However, surgery carries inherent risk, including infection, bleeding, and nerve damage...
April 22, 2024: Bone & joint open
https://read.qxmd.com/read/38638755/assessment-of-clinical-and-patient-centered-outcomes-in-nonsurgical-periodontal-therapy
#4
JOURNAL ARTICLE
Vyshnavi B Sindhusha, Arvina Rajasekar
Aim  The study was conducted to assess the clinical and patient-centered outcomes among the patients who had undergone nonsurgical periodontal therapy (NSPT). Methodology The participants for this study were 40 individuals with generalized chronic periodontitis. Numerous clinical parameters including clinical attachment level (CAL), probing pocket depth (PPD), plaque index (PI), and gingival index (GI) were evaluated along with the administration of a customized questionnaire before and after three months of therapy to evaluate patient-centered outcomes...
March 2024: Curēus
https://read.qxmd.com/read/38624046/clinical-course-of-patients-with-conservatively-managed-cerebral-cavernous-malformations
#5
JOURNAL ARTICLE
Abel Clemens Adriaan Sandmann, Marinus Abraham Kempeneers, René van den Berg, Dagmar Verbaan, William Peter Vandertop, Jonathan M Coutinho
INTRODUCTION: There is uncertainty whether patients with a cerebral cavernous malformation (CCM) should undergo conservative or surgical treatment, resulting in practice variation among hospitals. Our objective was to report clinical outcomes of patients with primarily conservatively managed CCMs. PATIENTS AND METHODS: This single-center cohort study included consecutive adult CCM patients, diagnosed in 2000-2023, who underwent conservative management as primary treatment strategy...
April 16, 2024: European Stroke Journal
https://read.qxmd.com/read/38622650/comparison-of-early-patient-reported-outcomes-between-uniportal-thoracoscopic-segmentectomy-and-wedge-resection-for-peripheral-small-sized-non-small-cell-lung-cancer
#6
JOURNAL ARTICLE
Yingzhi Zhao, Wenwu Liu, Xin Gao, Kaixin Zhang, Wei Dai, Xing Wei, Haoqian Zheng, Cheng Lei, Hongfan Yu, Qiuling Shi, Qiang Li, Tianpeng Xie
BACKGROUND: Analysis of patient-reported outcomes (PROs) offers valuable insights into distinguishing the effects of closely related medical procedures from the patient's perspective. In this study we compared symptom burden in patients undergoing uniportal thoracoscopic segmentectomy and wedge resection for peripheral small-sized non-small cell lung cancer (NSCLC). METHODS: This study included patients with peripheral NSCLC from an ongoing longitudinal prospective cohort study (CN-PRO-Lung 3) who underwent segmentectomy or wedge resection with tumor diameter ≤ 2 cm and consolidation tumor ratio (CTR) ≤ 0...
April 15, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38616797/effect-of-female-genital-mutilation-on-sexual-function-in-ibadan-nigeria
#7
JOURNAL ARTICLE
Promise Ifechukwu Okpara, Serap Tekbaş
Objective: Female genital mutilation, which harms women physically and psychologically, also causes serious problems in sexual life that continue throughout life. This study aimed to determine the impact of female genital mutilation on sexual outcomes in Ibadan, Nigeria. Method: This is a cross-sectional descriptive study. A self-administered questionnaire was used to obtain data from 161 women who agreed to participate in the study. After the data were collected, the sample group was divided into two groups those with female genital mutilation (84) and those without (77), and they were compared in terms of sexual outcomes...
2024: International Journal of Sexual Health
https://read.qxmd.com/read/38614387/three-year-outcomes-of-valoctocogene-roxaparvovec-gene-therapy-for-hemophilia-a
#8
JOURNAL ARTICLE
Bella Madan, Margareth C Ozelo, Priyanka Raheja, Emily Symington, Doris V Quon, Andrew D Leavitt, Steven W Pipe, Gillian Lowe, Gili Kenet, Mark T Reding, Jane Mason, Michael Wang, Annette von Drygalski, Robert Klamroth, Susan Shapiro, Hervé Chambost, Amy L Dunn, Johannes Oldenburg, Sheng-Chieh Chou, Flora Peyvandi, Carolyn M Millar, Dane Osmond, Hua Yu, Ebony Dashiell-Aje, Tara M Robinson, Johnny Mahlangu
BACKGROUND: Valoctocogene roxaparvovec transfers a human factor VIII (FVIII) coding sequence into hepatocytes of people with severe hemophilia A to provide bleeding protection. OBJECTIVE: Present 3-year efficacy and safety in the multicenter, open-label, single-arm, phase 3 GENEr8-1 trial. METHODS: GENEr8-1 enrolled 134 adult males with severe hemophilia A who were receiving FVIII prophylaxis. Efficacy endpoints included annualized bleeding rate (ABR), annualized FVIII utilization (AFU), FVIII activity (chromogenic substrate assay; imputed as 1 IU/dL at baseline and 0 IU/dL after discontinuation), and the Haemophilia-Specific Quality of Life Questionnaire for Adults (Haemo-QOL-A)...
April 11, 2024: Journal of Thrombosis and Haemostasis: JTH
https://read.qxmd.com/read/38612667/metabolic-dysregulation-and-its-role-in-postoperative-pain-among-knee-osteoarthritis-patients
#9
JOURNAL ARTICLE
Elena V Tchetina, Kseniya E Glemba, Galina A Markova, Svetlana I Glukhova, Maksim A Makarov, Aleksandr M Lila
UNLABELLED: Knee osteoarthritis (KOA) is characterized by low-grade inflammation, loss of articular cartilage, subchondral bone remodeling, synovitis, osteophyte formation, and pain. Strong, continuous pain may indicate the need for joint replacement in patients with end-stage OA, although postoperative pain (POP) of at least a two-month duration persists in 10-40% of patients with OA. STUDY PURPOSE: The inflammation observed in joint tissues is linked to pain caused by the production of proinflammatory cytokines...
March 29, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38605356/the-effect-of-individuals-oral-hygiene-habits-and-knowledge-levels-on-peri-implant-health-and-disease-a-questionnaire-based-observational-study
#10
JOURNAL ARTICLE
Tuğba Şahin
BACKGROUND: Peri-implant disease and health are associated with microbial dental plaque. Therefore, oral hygiene plays a role in preventing and treating these diseases. This study aimed to determine the relationships among knowledge of peri-implant status, oral hygiene habits, and peri-implant disease and health. METHODS: A total of 144 implants in nonsmokers with controlled systemic disease were included in the study. Peri-implant disease and the conditions of the implants were determined with periodontal indices and radiographs based on the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions and The EFP S3 level clinical practice guideline...
April 11, 2024: BMC Oral Health
https://read.qxmd.com/read/38602588/piroplasmid-infections-among-domestic-dogs-in-the-mountain-city-of-rio-de-janeiro-brazil
#11
JOURNAL ARTICLE
João Pedro Siqueira Palmer, Gilberto Salles Gazêta, Marcos Rogério André, Priscila Alves Fialho, Laís Lisboa Corrêa, José André Lessa Damasceno, Carolina Bistritschan Israel, Rafael Rempto Pereira, Alynne da Silva Barbosa
PURPOSE: The aim of the present study was to analyze the frequency of the piroplasmids in blood from dogs and ticks recovered from these animals in Teresópolis city, located in the mountain region of Rio de Janeiro state, Brazil. In addition to the clinical and hematological profile. METHODS: A total of 400 dogs attended in a veterinary clinic in this city between 2020 and 2021 were included. The blood was collected from the dogs, along with ticks and information on these dogs was obtained through a questionnaire applied to the owners...
April 11, 2024: Acta Parasitologica
https://read.qxmd.com/read/38597789/novel-definition-of-textbook-outcome-in-biliary-system-cancers-and-its-influence-on-patients-survival-and-quality-of-life
#12
JOURNAL ARTICLE
Manar Mikhail Atyah, Li Xu, Zhiying Yang
BACKGROUND: The definition of textbook outcome in biliary system cancers is a developing concept in need of expansion and investigation of its association with survival and quality of life. METHODS: In this original research, we developed a novel "all or none" textbook outcome definition which addresses the rapid recovery of post-surgical indexes, in addition to short-term mortality, hospital re-admission, prolonged stay, surgical margin and postoperative complications...
April 2024: Cancer Medicine
https://read.qxmd.com/read/38594493/impact-of-covid-19-infections-and-vaccination-on-menstrual-cycle-symptoms-in-the-south-of-jordan-a-cross-sectional-study
#13
JOURNAL ARTICLE
Mohammad A Abu-Lubad, Munir A Abu-Helalah, Mohammad S QawaQzeh, Esra'a F Alahmad, Malak M Al-Tamimi, Mohammad K Ruba'I, Sahm H Etoom, Rawan K Alfayoumi, Fatima E Aldaoudeyeh, Ekram A AlAbabneh, Ahlam M Al-Kharabsheh, Hussam Alshraideh
BACKGROUND: Several recent studies have highlighted the need for more evaluation of the impact of COVID-19 infections and vaccines on the reproductive system and menstruation. This study aimed to assess the impact of COVID-19 infection and vaccines on menstrual symptoms. METHODS: A cross-sectional survey utilizing face-to-face interviews from January 1 to 31 March 2022 was conducted in the city of Al-Karak in southern Jordan. The questionnaire included sociodemographic characteristics, medical and reproductive history, the contraceptive method used if any, menstrual cycle (MC) status, previous medical and drug history, and the impact of infection and vaccination on the MC...
April 10, 2024: Journal of the Egyptian Public Health Association
https://read.qxmd.com/read/38589820/the-impact-of-unmet-treatment-need-on-oral-health-related-quality-of-life-a-questionnaire-survey
#14
JOURNAL ARTICLE
Akshata Shetty, Rahul Bhandary, Dhruv Ahuja, Geetu Venugopalan, Enzo Grossi, Guilia Margherita Tartaglia, Shahnawaz Khijmatgar
BACKGROUND: Based on the present global burden of oral diseases, unmet dental needs affect a more significant population worldwide. It is characterised by the need for dental care but receiving delayed or no care. The contributing factors include lack of knowledge about oral health, its consequences, and the availability of dental services. We need to find out the scale of the problem of unmet dental needs for the south Indian population. Therefore, the objective was to determine the relationship between the presence of oral disease and the quality of life-related to oral health using the OHIP-14 tool...
April 8, 2024: BMC Oral Health
https://read.qxmd.com/read/38581329/epidemiological-survey-and-risk-factor-analysis-of-high-risk-human-papillomavirus-in-women-in-longgang-district-shenzhen
#15
JOURNAL ARTICLE
Xiaohong Sun, Xiaojing Sun
OBJECTIVE: The objective of this study was to assess the prevalence of high-risk HPV infection in married women in Longgang District, Shenzhen, and to analyze the distribution of HPV subtypes across different age groups while identifying risk factors associated with HPV infection. METHODS: 1. From January 2018 to December 2020, 209,627 married women in Longgang District were selected as study subjects, using high-risk HPV testing as the primary screening means. HPV 16 or 18 positive directly referred to colposcopy, other types positive continued liquid-based thin-layer cytology (TCT) examination, if ≥ ASCUS, referred to colposcopy, and biopsy if necessary...
April 5, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38579290/impact-on-diabetes-control-and-patient-reported-outcomes-of-a-newer-implantable-continuous-glucose-monitoring-system-eversense%C3%A2-cgm-system-a-single-centre-retro-and-prospective-observational-study
#16
JOURNAL ARTICLE
Dimitri Guy Rohner, Lukas Burget, Christoph Henzen, Stefan Fischli
AIMS OF THE STUDY: The Eversense® CGM System is the first and only continuous glucose monitoring system (CGMS) that uses a fully subcutaneous implanted sensor. This study aimed to evaluate effectiveness, safety and patient-reported outcomes in patients using the Eversense® CGM System in a realistic clinical setting, assessed at a single Swiss diabetes centre (Luzerner Kantonsspital) with prolonged follow-up. METHODS: This was a prospective and retrospective observational study that included patients with type 1 diabetes mellitus in whom at least one Eversense® glucose sensor was implanted between 2017 and 2022...
March 20, 2024: Swiss Medical Weekly
https://read.qxmd.com/read/38578507/quality-of-life-after-immune-suppressive-therapy-in-aplastic-anemia
#17
JOURNAL ARTICLE
Iris N Lommerse, Chris Hinnen, Liesbeth M van Vliet, Beke Schubert, Jens Panse, Constantijn J M Halkes, Jennifer M-L Tjon
Acquired aplastic anemia (AA) is a rare form of immune-mediated bone marrow failure, which can result in life-threatening infections or bleeding if left untreated. Treatment consists of either immune suppressive therapy (IST) or allogeneic stem cell transplantation (alloHSCT). While considerable research has been published regarding survival, response rate and toxicity of both treatments, knowledge on the impact on quality of life (QoL) is scarce. We used the recently developed AA-specific QoL questionnaire (QLQ-AA/PNH-54) to evaluate QoL in a single center cohort of AA patients who were successfully treated with IST...
April 5, 2024: Annals of Hematology
https://read.qxmd.com/read/38578181/validity-and-reliability-test-of-the-indonesian-version-of-the-pedhalshort-questionnaire
#18
JOURNAL ARTICLE
Novie Amelia Chozie, Dewi Rosariah Ayu, Bernie Endyarni Medise, Putri Maharani Tristanita Marsubrin, Teny Tjitra Sari, Irene Yuniar, Luh Karunia Wahyuni
INTRODUCTION: The PedHAL questionnaire is employed in measuring the activities of haemophilia children. The PedHALshort was developed in 2022 to determine the most relevant item for the assessment. Haemo-QoL questionnaire assesses the quality of life of haemophilia children. AIM: Determine the validity and reliability of the PedHALshort Indonesia language version compared to the Haemo-QoL in the Indonesian population. METHODS: A cross-sectional study was conducted in Jakarta, Indonesia...
April 5, 2024: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://read.qxmd.com/read/38577073/analysis-of-factors-impacting-postoperative-pain-and-quality-of-life-in-patients-with-mixed-hemorrhoids-a-retrospective-study
#19
JOURNAL ARTICLE
Xiao-Wen Sun, Jing-Yi Xu, Chang-Zhen Zhu, Si-Jia Li, Lu-Jia Jin, Zhi-Dong Zhu
BACKGROUND: Hemorrhoids are among the most common and frequently encountered chronic anorectal diseases in anorectal surgery. They are venous clusters formed by congestion, expansion, and flexion of the venous plexus in the lower part of the rectum. Mixed hemorrhoids bleed easily and recurrently, and this can result in severe anemia. Hence, they may have a negative effect on the health of the patient and surgical treatment is required. Milligan-Morgan hemorrhoidectomy has been widely used since 1937 for the treatment of grade III and IV hemorrhoids...
March 27, 2024: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38576234/self-screening-questionnaire-for-perianal-fistulizing-disease-in-patients-with-crohn-s-disease
#20
JOURNAL ARTICLE
O Seong Kweon, Ben Kang, Yoo Jin Lee, Eun Soo Kim, Sung Kook Kim, Hyun Seok Lee, Yun Jin Chung, Kyeong Ok Kim, Byung Ik Jang
BACKGROUND/AIMS: A poor prognostic factor for Crohn's disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing disease self-screening questionnaire for patients with CD. METHODS: This prospective pilot study was conducted at three tertiary referral centers between January 2019 and May 2020...
April 5, 2024: Korean Journal of Internal Medicine
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