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https://www.readbyqxmd.com/read/29218759/impact-of-pain-and-functional-impairment-in-us-adults-with-haemophilia-patient-reported-outcomes-and-musculoskeletal-evaluation-in-the-pain-functional-impairment-and-quality-of-life-p-fiq-study
#1
C L Kempton, M Recht, A Neff, M Wang, T W Buckner, A Soni, D Quon, M Witkop, L Boggio, R Z Gut, D L Cooper
INTRODUCTION: Standardized and disease-specific patient-reported outcome (PRO) instruments assessing pain, functional impairment and health-related quality of life (HRQoL) in people with haemophilia (PWH) have been used in studies, but infrequently in comprehensive care settings for individual assessment or treatment planning. AIM: To assess the impact of pain and functional impairment on HRQoL in PWH. METHODS: P-FiQ enrolled 381 adult PWH with a history of joint pain/bleeding and included 5 PROs and a clinical joint evaluation (Hemophilia Joint Health Score v2...
December 8, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29214383/evaluation-of-the-effectiveness-and-patients-contentment-with-transanal-haemorrhoidal-artery-dearterialisation-and-mucopexy-thd-for-treatment-of-haemorrhoidal-disease-a-6-year-study
#2
Qurat Ul Ain, Yasir Bashir, Emmanuel Eguare
INTRODUCTION: With high incidence of haemorrhoidal disease and significant complication rates of traditional haemorrhoidectomy procedures, transanal haemorrhoidal artery ligation and mucopexy (THD) emerges as a minimally invasive procedure with superior results. However, it is crucial that effectiveness of results and patient satisfaction be gauged based on post-operative experience, symptomology and recurrence. AIM: Our aim is to provide a long-term analysis of efficacy and patient's satisfaction for the procedure, for the largest patient population, in correlation to presenting symptoms and degree of haemorrhoids...
December 6, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29209208/the-clinical-pharmacokinetics-and-pharmacodynamics-of-warfarin-when-combined-with-compound-danshen-a-case-study-for-combined-treatment-of-coronary-heart-diseases-with-atrial-fibrillation
#3
Chunxiao Lv, Changxiao Liu, Zhuhua Yao, Xiumei Gao, Lanjun Sun, Jia Liu, Haibo Song, Ziqiang Li, Xi Du, Jinxia Sun, Yanfen Li, Kui Ye, Ruihua Wang, Yuhong Huang
Warfarin is used as anticoagulant and Compound Danshen prescription (CDP) is able to promote blood circulation. The combination might produce a synergic effect for patients of coronary heart diseases (CHDs) with atrial fibrillation (AF). Whether the combination increases the bleeding risk of warfarin is unclear, so the effects of Compound Danshen dripping pill (CDDP) on the pharmacokinetics (PK) and pharmacodynamics (PD) profiles of warfarin was investigated in patients. The dose and blood concentrations of warfarin, the four indicators of blood coagulation, prothrombin time, activated partial thromboplatin time, thrombin time, fibrinogen, and international normalized ratio value were compared when with and without CDDP treatment...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29204979/treatment-of-spontaneous-subarachnoid-hemorrhage-and-self-reported-neuropsychological-performance-at-6-months-results-of-a-prospective-clinical-pilot-study-on-good-grade-patients
#4
Elisabeth Bründl, Petra Schödel, Sylvia Bele, Martin Proescholdt, Judith Scheitzach, Florian Zeman, Alexander Brawanski, Karl-Michael Schebesch
AIM: Limited focus has been placed on neuropsychological patient profiles after spontaneous subarachnoid hemorrhage (sSAH). We conducted a prospective controlled study in good-grade sSAH patients to evaluate the time course of treatment-specific differences in cognitive processing after sSAH. MATERIAL AND METHODS: 26 consecutive sSAH patients were enrolled (drop out n=5). 9 patients received endovascular aneurysm occlusion (EV), 6 patients were treated microsurgically (MS), and 6 patients with perimesencephalic SAH (pSAH) underwent standardized intensive medical care...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29198583/substitution-urethroplasty-with-closure-versus-nonclosure-of-the-buccal-mucosa-graft-harvest-site-a-randomized-controlled-trial-with-a-detailed-analysis-of-oral-pain-and-morbidity
#5
Armin Soave, Roland Dahlem, Hans O Pinnschmidt, Michael Rink, Jessica Langetepe, Oliver Engel, Luis A Kluth, Birte Loechelt, Philip Reiss, Sascha A Ahyai, Margit Fisch
BACKGROUND: Optimal surgical management of the buccal mucosa harvest site in patients with urethral stricture disease during buccal mucosa graft urethroplasty (BMGU) remains controversial. OBJECTIVE: To analyze in detail intensity and quality of pain as well as oral morbidity following closure (C) versus nonclosure (NC) of the donor site. DESIGN, SETTING, AND PARTICIPANTS: Randomized controlled trial on 135 patients treated with BMGU between October 15, 2014 and December 18, 2015...
November 30, 2017: European Urology
https://www.readbyqxmd.com/read/29198540/severity-and-features-of-epistaxis-in-children-with-a-mucocutaneous-bleeding-disorder
#6
Eva Stokhuijzen, Catherine I Segbefia, Tina T Biss, Dewi S Clark, Paula D James, Jim Riddel, Victor S Blanchette, Margaret L Rand
OBJECTIVE: To use standardized bleeding questionnaires to compare the severity and patterns of epistaxis in children with a mucocutaneous bleeding disorder and control children. STUDY DESIGN: The epistaxis sections of the Pediatric Bleeding Questionnaire (PBQ) administered to pediatric patients with von Willebrand disease or a platelet function disorder and healthy control children were reviewed. Scores and features of epistaxis (frequency, duration, onset, site, seasonal correlation, and need for medical/surgical intervention) were recorded...
November 30, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29198061/development-and-pilot-testing-of-pharao-a-decision-support-system-for-pharmacological-risk-assessment-in-the-elderly
#7
Ylva Böttiger, Kari Laine, Tuomas Korhonen, Janne Lähdesmäki, Tero Shemeikka, Margaretha Julander, Maria Edlert, Marine L Andersson
PURPOSE: The aims of this study are to describe the development of PHARAO (Pharmacological Risk Assessment Online), a decision support system providing a risk profile for adverse events, associated with combined effects of multiple medicines, and to present data from a pilot study, testing the use, functionality, and acceptance of the PHARAO system in a clinical setting. METHODS: About 1400 substances were scored in relation to their risk to cause any of nine common and/or serious adverse effects...
December 2, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29193938/-knowledge-behavior-and-perception-of-oral-health-in-patients-with-type-2-diabetes
#8
Gabriela García-Morales, Denny Kennia Barrera-Lagunas
BACKGROUND: Periodontal disease occurs severely in patients with diabetes, also causes high blood glucose. The objective of this article was to determine knowledge, behavior and perception of oral health in patients with type 2 diabetes. METHODS: Cross-sectional study performed at the Unidad de Medicina Familiar No. 26 in Acapulco, Guerrero, México; 376 patients with type 2 diabetes were included. Sociodemographic questionnaire, knowledge, behavior and perception of oral health was applied...
September 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29175227/does-testosterone-treatment-increase-anger-expression-in-a-population-of-transgender-men
#9
Giovanna Motta, Chiara Crespi, Valentina Mineccia, Paolo Riccardo Brustio, Chiara Manieri, Fabio Lanfranco
BACKGROUND: The acquisition of phenotypic male features in transmen with gender dysphoria requires testosterone treatment. The suppression of menses is 1 of the most desired effects. The relation between testosterone levels and human aggressive behavior has been described. However, the effects of testosterone on anger expression have been poorly investigated in trans-persons. AIM: To assess the effects of testosterone treatment on anger expression in transmen using a validated self-report questionnaire (Spielberger's State-Trait Anger Expression Inventory-2 [STAXI-2])...
November 23, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29175136/the-liquid-facelift-first-hands-on-experience-with-facial-water-jet-assisted-liposuction-as-an-additive-technique-for-rhytidectomy-a-case-series-of-25-patients
#10
Kai O Kaye, Sonja Kästner, Felix J Paprottka, Phillipp Gonser
OBJECTIVE: Recently, water jet-assisted liposuction (WAL) was successfully applied by several other authors to remove fat and induce skin contraction in nonfacial body areas. Extending the range of indications for this new method, the authors of this article report on their first experience with its use in facial contouring, fat harvesting, and hydrodissection of the facial skin flap in rhytidectomy in a case series of 25 patients. METHODS: Twenty-five patients (median age: 56 years) had facelift surgery under sedation, and the WAL technique was used for facial contouring, fat harvesting for facial lipotransfer, and hydrodissection of the facial skin flap...
November 2, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29166183/the-development-of-an-interactive-health-education-model-based-on-the-djuwita-application-for-adolescent-girls
#11
Sri Djuwitaningsih, Setyowati
Alarming incidents of maternal deaths in Indonesia are due to three major causes: bleeding, sepsis, and hypertension, in addition to other non-obstetric causes and unsafe abortions. Adolescent girls contributed to maternal mortality based on early marriage, unwanted pregnancy, and childbirth. Prevention efforts have been taken through government programs and non-governmental organizations, but in practice those were considered ineffective. Thus, a preventative effort in the form of health education should be made, preferably embedded in a popular mobile application that most teenagers would be apt to use...
2017: Comprehensive Child and Adolescent Nursing
https://www.readbyqxmd.com/read/29159505/biochemical-stress-evaluation-after-medial-parapatellar-and-subvastus-approach-in-total-knee-replacement
#12
L Sabatini, G Nicolaci, F Atzori, A Oliva, A Aprato, M Terzolo, A Masse'
INTRODUCTION: Even if different surgical approaches for total knee arthroplasty are well known since decades, the standard medial parapatellar incision remains the most common one; general agreement about significant advantages with minimally invasive techniques is lacking. Furthermore, the surgical stress effect on the organism has always been analyzed through blood inflammatory parameters. This study aim was to compare the standard and subvastus approaches, using the salivary cortisol in particular as measure for systemic surgery-related stress...
November 20, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29139310/pudendal-nerve-injury-impairs-anorectal-function-and-health-related-quality-of-life-measures-%C3%A2-2-years-after-3d-conformal-radiotherapy-for-prostate-cancer
#13
Eng Eric Yeoh, Rochelle Botten, Addolorata Di Matteo, Marcus Tippett, Jonathon Hutton, Robert Fraser, Phillip G Dinning, David Wattchow
PURPOSE: To compare GI symptoms, measures of generic and disease specific health related quality of life (HRQoL), anorectal and pudendal nerve function and anal sphincter morphology between (i) patients ≥2 years after 3D conformal radiotherapy (3D-CRT)±high dose rate (HDR) brachytherapy for carcinoma of the prostate and aged matched patients before radiotherapy and (ii) symptomatic and asymptomatic patients ≥2 years after 3D-CRT ± HDR brachytherapy. MATERIAL AND METHODS: Methodology included: (i) modified LENT-SOMA scales for GI symptoms, (ii) EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires for generic and disease specific HRQoL, (iii) anorectal manometry and terminal motor latency for anorectal and pudendal nerve function and (iv) endorectal ultrasound for anal sphincter morphology...
November 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29138958/predictors-of-depression-in-iranian-women-with-polycystic-ovarian-syndrome
#14
Mojgan Mirghafourvand, Sakineh Mohammad-Alizadeh Charandabi, Tahereh Behroozi Lak, Fatemeh Aliasghari
Depression is a major complication of polycystic ovarian syndrome (PCOS). Lifestyle modification can prevent it. This study aimed to determine the predictors of depression in women with PCOS. This cross-sectional study was conducted on 174 women who attended in infertility clinics in Urmia-Iran, 2015. The data were collected through socio-demographic, Beck Depression Inventory-II and Health Promoting Lifestyle Profile-2 questionnaires. The mean (standard deviation) of total score of the depression was obtained 27...
November 14, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/29124995/peri-implant-soft-tissue-parameters-and-crestal-bone-levels-among-narghile-smokers-and-nonsmokers
#15
Tariq Abduljabbar, Nawaf Al-Hamoudi, Muath AlQunayan, Abdullah AlAhmari, Alwaleed AlMalki, Elham Gholamiazizi, Fahim Vohra
This retrospective convenient sample case-control study investigated the peri-implant soft-tissue inflammatory parameters and crestal bone loss (CBL) among narghile smokers (NS) (Group I) and nonsmoking controls (Group II). Demographic data were collected using a questionnaire. Peri-implant plaque index (PI), bleeding-on-probing (BOP) and pocket-depth (PD) were assessed; and peri-implant CBL was measured on standardized digital bite-wing radiographs. Sample-size was estimated and statistical analysis were done using Mann-Whitney U-test...
August 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29123383/internal-consistency-and-item-total-correlation-of-patient-reported-outcome-instruments-and-hemophilia-joint-health-score-v2-1-in-us-adult-people-with-hemophilia-results-from-the-pain-functional-impairment-and-quality-of-life-p-fiq-study
#16
Michael Wang, Katharine Batt, Craig Kessler, Anne Neff, Neeraj N Iyer, David L Cooper, Christine L Kempton
Background: The Pain, Functional Impairment, and Quality of Life study was an observational, cross-sectional assessment of the impact of pain on functional impairment and quality of life in adult people with hemophilia (PWH) of any severity in the USA who experience joint pain and/or bleeding. Objective: To assess internal consistency (IC) and item-total correlation (ITC) of assessment tools used in the Pain, Functional Impairment, and Quality of Life study. Methods: Participants completed 5 patient-reported outcome instruments (EQ-5D-5L with visual analog scale, Brief Pain Inventory v2 Short Form [BPI], International Physical Activity Questionnaire [IPAQ], Short Form 36 Health Survey v2 [SF-36v2], and Hemophilia Activities List [HAL]) and underwent an optional physiotherapist-administered musculoskeletal exam (Hemophilia Joint Health Score v2...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29119251/postoperative-complications-and-long-term-functional-outcome-in-children-operated-for-idiopathic-rectal-prolapse
#17
Elin Albertsdottir, Niels Qvist
PURPOSE: The aim of the present study was to evaluate the postoperative complications and the long-term gastrointestinal functional outcome after surgical treatment for rectal prolapse on a strategy with stapled anopexy for short (< 5 cm) prolapse and Delormes procedure for longer (> 5 cm) rectal prolapse. METHODS: A total of 38 patients were included with a postoperative follow-up period ranging from 1 month to 9.1 years. Thirty patients (83%) completed the Rome III questionnaire on gastrointestinal function, with the follow-up period ranging from 2 months to 7 years...
November 8, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29118151/vietnamese-oral-health-beliefs-and-practices-impact-on-the-utilization-of-western-preventive-oral-health-care
#18
Kim Yen T Nguyen, Dianne L Smallidge, Linda D Boyd, Lori Rainchuso
Purpose: Infrequent use of the Western health care by the Vietnamese may be explained by deeply-rooted traditional oral health beliefs and practices unique to the Asian culture. This study investigated Vietnamese oral health beliefs and practices and their relationship to the utilization of Western preventive oral health care services among Vietnamese-Americans.Methods: An exploratory, cross-sectional survey design with a convenience sample of 140 par-ticipants (n = 140) was used for this study. Participants were recruited on site of a Vietnamese-owned business, with questionnaires consisting of 28 questions that were distributed in hard copy by the principal investigator (PI) on multiple occasions and at various times of the day...
February 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29115727/bleeding-score-in-type-1-von-willebrand-disease-patients-using-the-isth-bat-questionnaire
#19
A Pathare, S Al Omrani, F Al Hajri, N Al Obaidani, B Al Balushi, K Al Falahi
BACKGROUND: Bleeding assessment tools have evolved in the last decade to standardize the assessment of the severity of bleeding symptom in a consistent way. In 2010, the International Society on Thrombosis and Hemostasis-Bleeding Assessment Tool (ISTH-BAT) was developed and validated. AIMS: Our aim was to administer ISTH-BAT questionnaire to the Omani patients with type 1 VWD and obtain the bleeding score (BS). We also studied the severity of their bleeding symptoms and correlated it with the BS as well as with the laboratory parameters...
November 8, 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/29109751/the-relation-of-preoperative-stress-and-anxiety-on-patients-satisfaction-after-implant-placement
#20
Houman Khorshidi, Fatemeh Lavaee, Janan Ghapanchi, Ali Golkari, Sara Kholousi
Background: There are some factors which can affect preoperative patient anxiety such as the necessity of procedure, postoperative pain, and patient's conception of his body image. The aim of this study was to assess the relation of patients' preoperative anxiety and postoperative patients' satisfaction in dental implant surgery. Materials and Methods: Dental implants were placed in 40 patients (19 male and 21 female) who were referred to Dental Implant Surgery Department in Imam Reza clinic, during March-December of 2014 in Shiraz...
September 2017: Dental Research Journal
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