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https://www.readbyqxmd.com/read/28081317/hormone-therapy-in-hypospadias-surgery-a-survey-on-the-current-practice-in-turkey
#1
Gülnur Göllü Bahadır, Ergun Ergün, Onur Telli, Farid Khanmammadov, Ahmet Murat Çakmak
BACKGROUND/AIM: Nowadays surgical intervention is possible in smaller phalluses and younger children with hypospadias disease. Different hormone treatments with different doses, modalities, indications, and treatment times come along with some disputes. The aim of this study is to evaluate the management approaches in hypospadias surgery of surgeons in regards to hormone preparations. MATERIALS AND METHODS: Questionnaires were sent via e-mail to 110 actively working pediatric surgeons and urologists...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28065788/western-dietary-pattern-increases-whereas-prudent-dietary-pattern-decreases-risk-of-incident-diverticulitis-in-a-prospective-cohort-study
#2
Lisa L Strate, Brieze R Keeley, Yin Cao, Kana Wu, Edward L Giovannucci, Andrew T Chan
BACKGROUND & AIMS: Dietary fiber is implicated as a risk factor for diverticulitis. Analyses of dietary patterns may provide information on risk beyond those of individual foods or nutrients. We examined whether major dietary patterns are associated with risk of incident diverticulitis. METHODS: We performed a prospective cohort study of 46,295 men who were free of diverticulitis and known diverticulosis in 1986 (baseline) using data from the Health Professionals Follow-up Study...
January 5, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28064338/-unknown-title
#3
V J Lund, Y Darby, J Rimmer, M Amin, S Husain
INTRODUCTION: Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disease characterized by recurrent epistaxis, mucocutaneous telangiectasia and visceral arteriovenous malformations. The nosebleeds can be life-threatening and in these circumstances, radical treatment is required. METHODS: Since 1994, closure of the nose has been undertaken to prevent severe nasal bleeding in patients meeting specific selection criteria. Outcome data collected on this cohort pre- and post-operatively is available for analysis...
January 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28052291/yogurt-containing-lactobacillus-gasseri-mitigates-aspirin-induced-small-bowel-injuries-a-prospective-randomized-double-blind-placebo-controlled-trial
#4
Takayoshi Suzuki, Aya Masui, Jun Nakamura, Hirokazu Shiozawa, Jun Aoki, Hirohiko Nakae, Shingo Tsuda, Jin Imai, Ozawa Hideki, Masashi Matsushima, Tetsuya Mine, Akira Tamura, Toshihiro Ohtsu, Yukio Asami, Atsushi Takagi
BACKGROUND: Although there is evidence about the beneficial effects of probiotics, their effects on aspirin-induced small bowel injuries have not been well examined. We evaluated the effects of the probiotic Lactobacillus gasseri OLL2716 (LG) on aspirin-induced small intestinal lesions, such as ulcers, erosions, reddened lesions, and bleeding. SUMMARY: This study enrolled 64 patients who received aspirin for more than 1 month and provided written informed consent to be part of the study...
2017: Digestion
https://www.readbyqxmd.com/read/28045313/parental-knowledge-and-practices-regarding-their-children-s-oral-health-in-kuwait
#5
L Alyahya
AIM: The purpose of this study is to assess the knowledge and practices of parents toward their children's oral health in Kuwait. MATERIALS AND METHODS: Study Design: A cross-sectional study was conducted among 300 parents who visited five dental specialty centers in Kuwait. Data were collected through a self-administered questionnaire. STATISTICS: The statistical analysis was performed using SPSS software (version 21; Inc., Chicago IL, USA)...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28042393/current-state-of-practice-for-colonic-diverticular-bleeding-in-37-hospitals-in-japan-a-multicenter-questionnaire-study
#6
Ryota Niikura, Naoyoshi Nagata, Hisashi Doyama, Ryosuke Ota, Naoki Ishii, Katsuhiro Mabe, Tsutomu Nishida, Takuto Hikichi, Kazuki Sumiyama, Jun Nishikawa, Toshio Uraoka, Shu Kiyotoki, Mitsuhiro Fujishiro, Kazuhiko Koike
AIM: To clarify the current state of practice for colonic diverticular bleeding (CDB) in Japan. METHODS: We conducted multicenter questionnaire surveys of the practice for CDB including clinical settings (8 questions), diagnoses (8 questions), treatments (7 questions), and outcomes (4 questions) in 37 hospitals across Japan. The answers were compared between hospitals with high and low number of inpatient beds to investigate which factor influenced the answers. RESULTS: Endoscopists at all 37 hospitals answered the questions, and the mean number of endoscopists at these hospitals was 12...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28036117/gingivitis-and-lifestyle-influences-on-hs-crp-and-il6-in-adolescents
#7
Vinay Pitchika, Elisabeth Thiering, Isabel Metz, Katrin Rothmaier, Anja Willenberg, Reinhard Hickel, Marie Standl, Thomas Kocher, Joachim Heinrich, Jan Kühnisch
AIM: This cross-sectional study was repeated at two time points and investigated the influence of gingivitis, smoking and body mass index (BMI) on the systemic inflammatory markers high-sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL6) in 10- and 15-year-olds. MATERIALS AND METHODS: The study sample of two birth cohorts, i.e., GINIplus and LISAplus, from the Munich centre consisted of 806 and 846 subjects who were evaluated at 10- and 15-year follow-ups, respectively...
December 30, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28035689/oral-health-of-children-with-attention-deficit-hyperactivity-disorder
#8
Yvonne C Y Chau, Kelly Y C Lai, Colman P J McGrath, Cynthia K Y Yiu
This study assessed and compared oral health and oral-health behaviours among children with and without attention deficit hyperactivity disorder (ADHD). The study included 31 children, 12-18 yr of age, with ADHD and 31 age- and gender-matched children without ADHD. Clinical data were recorded by a trained and calibrated examiner for caries, traumatic dental injuries, periodontal health, tooth wear, and salivary function. A questionnaire was also given to parents or caregivers about the oral health habits and behaviours of these children...
December 30, 2016: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/28031049/clinical-and-radiological-features-driving-patient-selection-for-antiangiogenic-therapy-in-non-small-cell-lung-cancer-nsclc
#9
Cesare Gridelli, Andrea Camerini, Giovanni Pappagallo, Angelo Pennella, Michele Anzidei, Massimo Bellomi, Roberta Buosi, Rosario Francesco Grasso
BACKGROUND: The use of antiangiogenic therapy in non-small cell lung cancer (NSCLC) requires thorough evaluation of patient characteristics in order to avoid potential safety issues, particularly pulmonary haemorrhage (PH). The aim of this consensus by a panel of experts was to identify important criteria for the selection of patients with NSCLC who would benefit from antiangiogenic therapy. METHODS: Radiologists and oncologists were selected for the expert panel...
December 28, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/28026074/measurement-properties-of-the-haem-a-qol-in-haemophilia-clinical-trials
#10
S von Mackensen, A Eldar-Lissai, P Auguste, S Krishnan, R von Maltzahn, R Yu, K W Wyrwich
INTRODUCTION: Patients with haemophilia on long-acting prophylactic treatment may experience an improvement in health-related quality of life (HRQoL) through reductions in breakthrough bleeds and associated complications, including long-term joint damage, compared with episodic treatment. AIM: This analysis examined clinical trial data to understand the psychometric characteristics (reliability, validity and sensitivity to change over time) of the Haem-A-QoL Questionnaire in adult males with haemophilia...
December 27, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28008192/the-long-term-results-and-changing-patterns-of-biological-valves-at-the-mitral-position-in-contemporary-practice-in-japan
#11
Tomonobu Abe, Hideki Ito, Masato Mutsuga, Kazuro Fujimoto, Sachie Terazawa, Yuji Narita, Hideki Oshima, Akihiko Usui
Mitral valve surgery has changed with the wide acceptance of mitral valve repair. The aim of this study is to obtain the long-term results of patients who underwent mitral valve replacement (MVR) using a biological prosthesis in contemporary practice in Japan. From January 1990 to December 2013, 76 patients underwent MVR using a biological prosthesis with or without concomitant surgery. Data were obtained by means of a questionnaire and a telephone interview. The mean follow-up period was 4.26 years. The etiologies of the patients included dilated cardiomyopathy (DCM) (n=20 [26...
December 2016: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28005253/diverging-conclusions-from-the-same-meta-analysis-in-drug-safety-source-of-data-primary-versus-secondary-takes-a-toll
#12
Guillermo Prada-Ramallal, Bahi Takkouche, Adolfo Figueiras
INTRODUCTION: Meta-analyses of observational studies represent an important tool for assessing efficacy and safety in the pharmacoepidemiologic field. The data from the individual studies are either primary (i.e., collected through interviews or self-administered questionnaires) or secondary (i.e., collected from databases that were established for other purposes). So far, the origin of the data (primary vs. secondary) has not been systematically assessed as a source of heterogeneity in pharmacoepidemiologic meta-analyses...
December 22, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27998672/quantitation-of-bleeding-symptoms-in-a-national-registry-of-patients-with-inherited-platelet-disorders
#13
Shoshana Revel-Vilk, Chana Richter, Tal Ben-Ami, Joanne Yacobovich, Shraga Aviner, Ayelet Ben-Barak, Amir Asher Kuperman, Shira Ben-Barak, Chaim Kaplinsky, Hagit Miskin, Hannah Tamary, Gili Kenet
BACKGROUND: Inherited platelet deficiency and/or dysfunction may be more common in the general population than has previously been appreciated. In 2013 the Israeli Inherited Platelet Disorder (IPD) Registry was established. METHODS: Clinical and laboratory data were collected to pre-specified registration forms. The study protocol was approved by the local hospital ethics committees. RESULTS: To date we have included in the registry 89 patients (male 52%) from 79 families...
December 17, 2016: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/27996999/-real-life-clinical-management-of-nonvalvular-atrial-fibrillation-results-from-the-italian-epidemiological-survey-experience-on-the-use-of-rivaroxaban
#14
Paolo Colonna, Fabrizio Ammirati
BACKGROUND: Atrial fibrillation-related stroke prevention with anticoagulant drugs is currently evolving towards the introduction into clinical practice of the new oral anticoagulants, including rivaroxaban. Our aim was to evaluate in a real-life setting the characteristics and management of patients with nonvalvular atrial fibrillation to whom Italian doctors decided to prescribe rivaroxaban. METHODS: Between January and February 2014, a group of 95 physicians collected aggregate retrospective data, through an online questionnaire, on 1127 patients with nonvalvular atrial fibrillation receiving rivaroxaban...
November 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27995007/direct-new-oral-anticoagulants-follow-up-guidelines-and-bleeding-complications-in-general-practice-a-survey-of-swiss-general-internal-medicine-practitioners
#15
Thomas C Sauter, Carlo Melis, Wolf E Hautz, Meret E Ricklin, Aristomenis K Exadaktylos
BACKGROUND: The present study investigated how much Swiss general internal medicine practitioners (GPs) know about new direct oral anticoagulants (NOACs), particularly the relevant guidelines, follow-up tests, dosing adjustments, indications and complications. We conducted a paper-based survey of GPs, performed in Bern, Switzerland. Our questionnaire assessed the physicians' preference for NOACs rather than vitamin K antagonists (VKA), prevalence and choice of NOAC, clinical follow-up including follow-up blood testing, and bleeding complications...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27956157/ibrutinib-for-patients-with-rituximab-refractory-waldenstr%C3%A3-m-s-macroglobulinaemia-innovate-an-open-label-substudy-of-an-international-multicentre-phase-3-trial
#16
Meletios A Dimopoulos, Judith Trotman, Alessandra Tedeschi, Jeffrey V Matous, David Macdonald, Constantine Tam, Olivier Tournilhac, Shuo Ma, Albert Oriol, Leonard T Heffner, Chaim Shustik, Ramón García-Sanz, Robert F Cornell, Carlos Fernández de Larrea, Jorge J Castillo, Miquel Granell, Marie-Christine Kyrtsonis, Veronique Leblond, Argiris Symeonidis, Efstathios Kastritis, Priyanka Singh, Jianling Li, Thorsten Graef, Elizabeth Bilotti, Steven Treon, Christian Buske
BACKGROUND: In the era of widespread rituximab use for Waldenström's macroglobulinaemia, new treatment options for patients with rituximab-refractory disease are an important clinical need. Ibrutinib has induced durable responses in previously treated patients with Waldenström's macroglobulinaemia. We assessed the efficacy and safety of ibrutinib in a population with rituximab-refractory disease. METHODS: This multicentre, open-label substudy was done at 19 sites in seven countries in adults aged 18 years and older with confirmed Waldenström's macroglobulinaemia, refractory to rituximab and requiring treatment...
December 9, 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27931020/long-term-clinical-course-after-conservative-and-endoscopic-treatment-of-colonic-diverticular-bleeding
#17
Akira Mizuki, Masayuki Tatemichi, Atsushi Nakazawa, Nobuhiro Tsukada, Hiroshi Nagata, Takanori Kanai
BACKGROUND/AIM: What naturally happens to patients after they undergo conservative and endoscopic treatment of colonic diverticular bleeding (CDB) is largely unknown. We retrospectively track the long-term outcome of the recurrence of CDB between patients with endoscopic and conservative treatment. METHODS: The group was divided into 2 groups: patients treated with injection and/or clipping (endoscopic group) and patients in whom such treatment could not be performed (conservative group)...
December 9, 2016: Digestion
https://www.readbyqxmd.com/read/27928900/determining-the-health-related-quality-of-life-in-individuals-with-haemophilia-in-developing-economies-results-from-the-brazilian-population
#18
T Salomon, D G Chaves, S Brener, P R J Martins, J V M Mambrini, S V Peixoto
INTRODUCTION: Several studies show the negative impact of haemophilia in health-related quality of life (HRQOL). This issue is not well explored in developing countries. OBJECTIVES: This cross-sectional study aimed to evaluate the HRQOL and its associated factors in patients with haemophilia A/B in Brazil. Data were collected by questionnaire and in medical records, including a Portuguese version of Haem-A-Qol. RESULTS: Brazilian patients were invited to the study and 175 participants (147 haemophilics A and 28 haemophilics B) were included...
December 8, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27923286/knowledge-and-attitudes-of-female-university-students-on-menstrual-cycle-and-contraception
#19
Márta Szűcs, Tamás Bitó, Csaba Csíkos, Andrea Párducz Szöllősi, Cristian Furau, Iolanda Blidaru, Aleksandra Kapamadzija, Katarina Sedlecky, György Bártfai
Socioeconomic changes, as well as the development of new contraceptive modalities may influence women's preferences in the selection of a method of contraception. The aim of this study was to evaluate the knowledge, opinions and attitudes of female university students regarding the menstrual cycle, sexual health and contraception. A questionnaire-based survey was conducted among 2572 female university students in Hungary, Romania and Serbia, between November 2009 and January 2011. A higher proportion of students of health sciences than students of other faculties had appropriate knowledge of the fertile period within a menstrual cycle: 86...
December 6, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27903265/associations-among-oral-health-related-quality-of-life-subjective-symptoms-clinical-status-and-self-rated-oral-health-in-japanese-university-students-a-cross-sectional-study
#20
Mayu Yamane-Takeuchi, Daisuke Ekuni, Shinsuke Mizutani, Kota Kataoka, Ayano Taniguchi-Tabata, Tetsuji Azuma, Michiko Furuta, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita
BACKGROUND: The present study aimed to elucidate the associations among self-rated oral health, clinical oral health status, oral health behaviors, subjective oral symptoms, and oral health-related quality of life (OHRQoL) in a group of Japanese university students. METHODS: Of 2051 participants, 2027 (98.83%) students received an optional oral examination and answered a questionnaire including items regarding age, sex, self-rated oral health, oral health behaviors, subjective oral symptoms, and OHRQoL [The Oral Health Impact Profile (OHIP)-14]...
November 30, 2016: BMC Oral Health
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